Arsenic-containing hydrocarbons are toxic in the in vivo model Drosophila melanogaster
- Arsenic-containing hydrocarbons (AsHC) constitute one group of arsenolipids that have been identified in seafood. In this first in vivo toxicity study for AsHCs, we show that AsHCs exert toxic effects in Drosophila melanogaster in a concentration range similar to that of arsenite. In contrast to arsenite, however, AsHCs cause developmental toxicity in the late developmental stages of Drosophila melanogaster. This work illustrates the need for a full characterisation of the toxicity of AsHCs in experimental animals to finally assess the risk to human health related to the presence of arsenolipids in seafood.
| Author details: | Sören MeyerGND, Jacqueline Schulz, Astrid Jeibmann, Mojtaba S. Taleshi, Franziska EbertORCiDGND, Kevin Francesconi, Tanja SchwerdtleORCiDGND |
|---|---|
| ISSN: | 1756-5901 |
| Title of parent work (English): | Metallomics |
| Publisher: | The Royal Society of Chemistry |
| Place of publishing: | Cambridge |
| Editor(s): | Tanja Schwerdtle |
| Publication type: | Article |
| Language: | English |
| Date of first publication: | 2014/09/29 |
| Publication year: | 2014 |
| Release date: | 2015/05/13 |
| Tag: | arsenolipids present; cod-liver; fatty-acids; fish; identification; oil; rp-hplc |
| Number of pages: | 5 |
| First page: | 2010 |
| Last Page: | 2014 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| DDC classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
| Peer review: | Referiert |
| Publishing method: | Open Access |
| Grantor: | RSC |
| License (English): |  Creative Commons - Namensnennung 3.0 Unported |
| External remark: | Zweitveröffentlichung in der Schriftenreihe Postprints der Universität Potsdam : Humanwissenschaftliche Reihe ; 183 |
