Scope and limitations of the Heck-Matsuda-coupling of phenol diazonium salts and styrenes: a protecting-group economic synthesis of phenolic stilbenes
- 4-Phenol diazonium salts undergo Pd-catalyzed Heck reactions with various styrenes to 4ï-hydroxy stilbenes. In almost all cases higher yields and fewer side products were observed, compared to the analogous 4-methoxy benzene diazonium salts. In contrast, the reaction fails completely with 2- and 3-phenol diazonium salts. For these substitution patterns the methoxy-substituted derivatives are superior.
| Author details: | Bernd SchmidtORCiDGND, Nelli Elizarov, René BergerGND, Frank Hölter |
|---|---|
| URL: | http://pubs.rsc.org/en/content/articlepdf/2013/ob/c3ob40420j |
| DOI: | https://doi.org/10.1039/C3OB40420J |
| ISSN: | 1477-0520 |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2014 |
| Publication year: | 2014 |
| Release date: | 2017/03/25 |
| Source: | Organic and biomolecular chemistry. - ISSN 1477-0520. - 11 (2013) 22, S. 3674 - 3691 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
