Evaluation of the Accuracy of the LumiraDx INR Test Using Patients in Receipt of Phenprocoumon Anticoagulation Therapy
- Background: The LumiraDx INR Test is a new point-of-care diagnostic test designed to analyze fingerstick blood samples. The test was assessed in patients receiving phenprocoumon (NCT04074980). Methods: Venous plasma international normalized ratio (INR) was measured using the LumiraDx INR Test. LumiraDx INR Test-ascertained capillary whole blood INR was compared with venous plasma INR measured using the IL ACL Elite Pro and Sysmex CS-5100 reference instruments. Results: A total of 102 patients receiving phenprocoumon were recruited. The INR results from venous plasma and capillary whole blood that were analyzed on the LumiraDx INR Test correlated well with those measured using the IL ACL Elite Pro (plasma: n = 25, r = 0.981; capillary blood: n = 74, r = 0.949) and the Sysmex CS-5100 (n = 73, r = 0.950). Conclusions: The LumiraDx INR Test showed high accuracy in analyzing venous plasma and capillary whole blood from patients receiving phenprocoumon.
| Author details: | Heinz VöllerORCiDGND, Karen Heyne |
|---|---|
| DOI: | https://doi.org/10.1097/POC.0000000000000207 |
| ISSN: | 1533-029X |
| ISSN: | 1533-0303 |
| Title of parent work (English): | Point of care : the journal of near-patient testing & technology |
| Publisher: | Lippincott Williams & Wilkins |
| Place of publishing: | Philadelphia |
| Publication type: | Article |
| Language: | English |
| Date of first publication: | 2020/09/01 |
| Publication year: | 2020 |
| Release date: | 2023/01/25 |
| Tag: | LumiraDx INR Test; LumiraDx Platform; international normalized ratio; oral anticoagulation; phenprocoumon; point-of-care; vitamin K antagonist therapy |
| Volume: | 19 |
| Issue: | 3 |
| Number of pages: | 5 |
| First page: | 72 |
| Last Page: | 76 |
| Funding institution: | LumiraDx UK Ltd, Dumyat Business Park, Alloa, UK |
| Organizational units: | Humanwissenschaftliche Fakultät / Strukturbereich Kognitionswissenschaften / Department Sport- und Gesundheitswissenschaften |
| DDC classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Peer review: | Referiert |
| Publishing method: | Open Access / Bronze Open-Access |
