Scope and limitations of the Heck-Matsuda-coupling of phenol diazonium salts and styrenes a protecting-group economic synthesis of phenolic stilbenes
- 4-Phenol diazonium salts undergo Pd-catalyzed Heck reactions with various styrenes to 4'-hydroxy stilbenes. In almost all cases higher yields and fewer side products were observed, compared to the analogous 4-methoxy benzene diazonium salts. In contrast, the reaction fails completely with 2- and 3-phenol diazonium salts. For these substitution patterns the methoxy-substituted derivatives are superior.
| Author details: | Bernd SchmidtORCiDGND, Nelli Elizarov, René BergerGND, Frank Hoelter |
|---|---|
| DOI: | https://doi.org/10.1039/c3ob40420j |
| ISSN: | 1477-0520 |
| Title of parent work (English): | Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry |
| Publisher: | Royal Society of Chemistry |
| Place of publishing: | Cambridge |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2013 |
| Publication year: | 2013 |
| Release date: | 2017/03/26 |
| Volume: | 11 |
| Issue: | 22 |
| Number of pages: | 18 |
| First page: | 3674 |
| Last Page: | 3691 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
