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Design, preparation and assessment of surface-immobilised tetraphenylethenes for biosensing applications
- Tetraphenylethene (TPE) shows a significant increase of fluorescence intensity when the rotational freedom of its phenyl groups is restricted. This special property allows the use of TPE in sensor applications, which have been previously described for the liquid phase only. However, some applications utilising arrays require the immobilisation of TPE dyes on solid surfaces. In this work, we synthesised and investigated the fluorescence behaviour of TPE derivatives on silica particles and quartz slides and suggest ways to employ the dye's properties in solid phase biosensor applications. 2014 Published by Elsevier B.V.
| Author details: | Johannes Brennecke, Christopher J. Ochs, Aicha Boudhar, Bastien Reux, Gomathy Sandhya Subramanian, Martin J. Lear, Dieter Trau, Jonathan Hobley |
|---|---|
| DOI: | https://doi.org/10.1016/j.apsusc.2014.04.061 |
| ISSN: | 0169-4332 |
| ISSN: | 1873-5584 |
| Title of parent work (English): | Applied surface science : a journal devoted to applied physics and chemistry of surfaces and interfaces |
| Publisher: | Elsevier |
| Place of publishing: | Amsterdam |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2014 |
| Publication year: | 2014 |
| Release date: | 2017/03/27 |
| Tag: | Microparticles Reagentless assay; Tetraphenylethene Bioassay Fluorescent dye |
| Volume: | 307 |
| Number of pages: | 7 |
| First page: | 475 |
| Last Page: | 481 |
| Funding institution: | National University of Singapore (NUS) [R397000154112, R397000150592]; National Research Foundation Singapore (SMART Scholars fund) [S900074]; A-STAR Joint Council Offic [10/03/FG/06/04]; Studienstiftung des deutschen Volkes and the Agency for Science, Technology and Research (A*Star) |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
