Alkyne-X modification of polypeptoids
- Poly(N-propargyl glycine) (PNPG) can be readily prepared by ring-opening polymerization of N-propargyl glycine N-carboxyanhydride (NCA) and modified using various addition reactions such as copper catalyzed [3+2] cycloaddition of azide, radical (photo-)addition of thiol, nucleophilic addition of ethylene oxide, and thermal induced cross-linking. It is demonstrated that PNPG can serve as a modular platform to produce a bibliography of novel functional polypeptoid or pseudopeptide materials, including polypeptoid ionic liquids and graft copolymers.
| Author details: | Christian Secker, Joshua W. Robinson, Helmut SchlaadORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1016/j.eurpolymj.2014.08.028 |
| ISSN: | 0014-3057 |
| ISSN: | 1873-1945 |
| Title of parent work (English): | European polymer journal |
| Publisher: | Elsevier |
| Place of publishing: | Oxford |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2015 |
| Publication year: | 2015 |
| Release date: | 2017/03/27 |
| Tag: | Click chemistry; NCA; Polypeptoid; Post-polymerization modification |
| Volume: | 62 |
| Number of pages: | 6 |
| First page: | 394 |
| Last Page: | 399 |
| Funding institution: | Max Planck Society |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
