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Arsenic-containing hydrocarbons are toxic in the in vivo model Drosophila melanogaster

  • Arsenic-containing hydrocarbons (AsHC) constitute one group of arsenolipids that have been identified in seafood. In this first in vivo toxicity study for AsHCs, we show that AsHCs exert toxic effects in Drosophila melanogaster in a concentration range similar to that of arsenite. In contrast to arsenite, however, AsHCs cause developmental toxicity in the late developmental stages of Drosophila melanogaster. This work illustrates the need for a full characterisation of the toxicity of AsHCs in experimental animals to finally assess the risk to human health related to the presence of arsenolipids in seafood.

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Metadaten
Author details:Sören MeyerGND, Jacqueline Schulz, Astrid Jeibmann, Mojtaba S. Taleshi, Franziska EbertORCiDGND, Kevin Francesconi, Tanja SchwerdtleORCiDGND
URN:urn:nbn:de:kobv:517-opus4-76819
Publication series (Volume number):Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (183)
Publication type:Postprint
Language:English
Date of first publication:2014/09/29
Publication year:2014
Publishing institution:Universität Potsdam
Release date:2015/05/13
Tag:arsenolipids present; cod-liver; fatty-acids; fish; identification; oil; rp-hplc
Volume:11
Issue:6
Number of pages:5
First page:2010
Last Page:2014
Source:Metallomics, 2014,6, 2010-2014. DOI: 10.1039/C4MT00249K
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
DDC classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
Peer review:Referiert
Publishing method:Open Access
License (English):License LogoCreative Commons - Namensnennung 3.0 Unported
External remark:Bibliographieeintrag der Originalveröffentlichung/Quelle
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