Self-Assembly into multicompartment micelles and selective solubilization by Hydrophilic-Lipophilic-Fluorophilic block copolymers

  • Amphiphilic linear ternary block copolymers (ABC) were synthesized in three consecutive steps by the reversible addition fragmentation chain transfer (RAFT) method. Using oligo(ethylene oxide) monomethyl ether acrylate, benzyl acrylate, and 1H,1H-perfluorobutyl acrylate monomers, the triblock copolymers consist of a hydrophilic (A), a lipophilic (B), and a fluorophilic (C) block. The block sequence of the triphilic copolymers was varied systematically to provide all possible variations: ABC, ACB, and BAC. All blocks have glass transition temperatures below 0 degrees C. Self-assembly into spherical micellar aggregates was observed in aqueous solution, where hydrophobic cores undergo local phase separation into various ultrastructures as shown by cryogenic transmission electron microscopy (cryo-TEM). Selective solubilization of substantial quantities of hydrocarbon and fluorocarbon low molar mass compounds by the lipophilic and fluorophilic block, respectively, is demonstrated.

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Author:Jean-Noel Marsat, Matthias Heydenreich, Erich Kleinpeter, Hans V. Berlepsch, Christoph Boettcher, André LaschewskyORCiDGND
ISSN:0024-9297 (print)
Parent Title (English):Macromolecules : a publication of the American Chemical Society
Publisher:American Chemical Society
Place of publication:Washington
Document Type:Article
Year of first Publication:2011
Year of Completion:2011
Release Date:2017/03/26
First Page:2092
Last Page:2105
Funder:Deutsche Forschungsgemeinschaft [LA611/5, B01000/8]
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
Peer Review:Referiert