TY  - JOUR
A1  - Wittig, Alice
A1  - Miranda, Fabio Malcher
A1  - Hölzer, Martin
A1  - Altenburg, Tom
A1  - Bartoszewicz, Jakub Maciej
A1  - Beyvers, Sebastian
A1  - Dieckmann, Marius Alfred
A1  - Genske, Ulrich
A1  - Giese, Sven Hans-Joachim
A1  - Nowicka, Melania
A1  - Richard, Hugues
A1  - Schiebenhoefer, Henning
A1  - Schmachtenberg, Anna-Juliane
A1  - Sieben, Paul
A1  - Tang, Ming
A1  - Tembrockhaus, Julius
A1  - Renard, Bernhard Y.
A1  - Fuchs, Stephan
T1  - CovRadar
BT  - continuously tracking and filtering SARS-CoV-2 mutations for genomic surveillance
JF  - Bioinformatics
N2  - The ongoing pandemic caused by SARS-CoV-2 emphasizes the importance of genomic surveillance to understand the evolution of the virus, to monitor the viral population, and plan epidemiological responses. Detailed analysis, easy visualization and intuitive filtering of the latest viral sequences are powerful for this purpose. We present CovRadar, a tool for genomic surveillance of the SARS-CoV-2 Spike protein. CovRadar consists of an analytical pipeline and a web application that enable the analysis and visualization of hundreds of thousand sequences. First, CovRadar extracts the regions of interest using local alignment, then builds a multiple sequence alignment, infers variants and consensus and finally presents the results in an interactive app, making accessing and reporting simple, flexible and fast.
Y1  - 2022
U6  - https://doi.org/10.1093/bioinformatics/btac411
SN  - 1367-4803
SN  - 1367-4811
VL  - 38
IS  - 17
SP  - 4223
EP  - 4225
PB  - Oxford Univ. Press
CY  - Oxford
ER  -