TY - JOUR A1 - Felser, Claudia A1 - Jessen, Anna T1 - Correlative coordination and variable subject-verb agreement in German JF - Languages : open access journal N2 - Coordinated subjects often show variable number agreement with the finite verb, but linguistic approaches to this phenomenon have rarely been informed by systematically collected data. We report the results from three experiments investigating German speakers' agreement preferences with complex subjects joined by the correlative conjunctions sowohl horizontal ellipsis als auch ('both horizontal ellipsis and'), weder horizontal ellipsis noch ('neither horizontal ellipsis nor') or entweder horizontal ellipsis oder ('either horizontal ellipsis or'). We examine to what extent conjunction type and a conjunct's relative proximity to the verb affect the acceptability and processibility of singular vs. plural agreement. Experiment 1 was an untimed acceptability rating task, Experiment 2 a timed sentence completion task, and Experiment 3 was a self-paced reading task. Taken together, our results show that number agreement with correlative coordination in German is primarily determined by a default constraint triggering plural agreement, which interacts with linear order and semantic factors. Semantic differences between conjunctions only affected speakers' agreement preferences in the absence of processing pressure but not their initial agreement computation. The combined results from our offline and online experimental measures of German speakers' agreement preferences suggest that the constraints under investigation do not only differ in their relative weighting but also in their relative timing during agreement computation. KW - correlative coordination KW - subject– verb agreement KW - German Y1 - 2021 U6 - https://doi.org/10.3390/languages6020067 SN - 2226-471X VL - 6 IS - 2 PB - MDPI CY - Basel ER - TY - JOUR A1 - Tofelde, Stefanie A1 - Bufe, Aaron A1 - Turowski, Jens M. T1 - Hillslope Sediment Supply Limits Alluvial Valley Width JF - AGU Advances N2 - River-valley morphology preserves information on tectonic and climatic conditions that shape landscapes. Observations suggest that river discharge and valley-wall lithology are the main controls on valley width. Yet, current models based on these observations fail to explain the full range of cross-sectional valley shapes in nature, suggesting hitherto unquantified controls on valley width. In particular, current models cannot explain the existence of paired terrace sequences that form under cyclic climate forcing. Paired river terraces are staircases of abandoned floodplains on both valley sides, and hence preserve past valley widths. Their formation requires alternating phases of predominantly river incision and predominantly lateral planation, plus progressive valley narrowing. While cyclic Quaternary climate changes can explain shifts between incision and lateral erosion, the driving mechanism of valley narrowing is unknown. Here, we extract valley geometries from climatically formed, alluvial river-terrace sequences and show that across our dataset, the total cumulative terrace height (here: total valley height) explains 90%–99% of the variance in valley width at the terrace sites. This finding suggests that valley height, or a parameter that scales linearly with valley height, controls valley width in addition to river discharge and lithology. To explain this valley-width-height relationship, we reformulate existing valley-width models and suggest that, when adjusting to new boundary conditions, alluvial valleys evolve to a width at which sediment removal from valley walls matches lateral sediment supply from hillslope erosion. Such a hillslope-channel coupling is not captured in current valley-evolution models. Our model can explain the existence of paired terrace sequences under cyclic climate forcing and relates valley width to measurable field parameters. Therefore, it facilitates the reconstruction of past climatic and tectonic conditions from valley topography. Y1 - 2022 U6 - https://doi.org/10.1029/2021AV000641 SN - 2576-604X PB - American Geophysical Union (AGU); Wiley CY - Hoboken, New Jersey, USA ER - TY - JOUR A1 - Park, Jaeheung A1 - Stolle, Claudia A1 - Yamazaki, Yosuke A1 - Rauberg, Jan A1 - Michaelis, Ingo A1 - Olsen, Nils T1 - Diagnosing low-/mid-latitude ionospheric currents using platform magnetometers BT - CryoSat-2 and GRACE-FO JF - Earth, planets and space N2 - Electric currents flowing in the terrestrial ionosphere have conventionally been diagnosed by low-earth-orbit (LEO) satellites equipped with science-grade magnetometers and long booms on magnetically clean satellites. In recent years, there are a variety of endeavors to incorporate platform magnetometers, which are initially designed for navigation purposes, to study ionospheric currents. Because of the suboptimal resolution and significant noise of the platform magnetometers, however, most of the studies were confined to high-latitude auroral regions, where magnetic field deflections from ionospheric currents easily exceed 100 nT. This study aims to demonstrate the possibility of diagnosing weak low-/mid-latitude ionospheric currents based on platform magnetometers. We use navigation magnetometer data from two satellites, CryoSat-2 and the Gravity Recovery and Climate Experiment Follow-On (GRACE-FO), both of which have been intensively calibrated based on housekeeping data and a high-precision geomagnetic field model. Analyses based on 8 years of CryoSat-2 data as well as similar to 1.5 years of GRACE-FO data reproduce well-known climatology of inter-hemispheric field-aligned currents (IHFACs), as reported by previous satellite missions dedicated to precise magnetic observations. Also, our results show that C-shaped structures appearing in noontime IHFAC distributions conform to the shape of the South Atlantic Anomaly. The F-region dynamo currents are only partially identified in the platform magnetometer data, possibly because the currents are weaker than IHFACs in general and depend significantly on altitude and solar activity. Still, this study evidences noontime F-region dynamo currents at the highest altitude (717 km) ever reported. We expect that further data accumulation from continuously operating missions may reveal the dynamo currents more clearly during the next solar maximum. KW - Platform magnetometers KW - CryoSat-2 KW - GRACE-FO KW - Inter-hemispheric KW - field-aligned currents KW - F-region dynamo currents Y1 - 2020 U6 - https://doi.org/10.1186/s40623-020-01274-3 SN - 1343-8832 SN - 1880-5981 VL - 72 IS - 1 PB - Springer CY - New York ER - TY - JOUR A1 - Miklashevsky, Alex A1 - Fischer, Martin H. A1 - Lindemann, Oliver T1 - Spatial-numerical associations without a motor response? Grip force says ‘Yes’ JF - Acta Psychologica N2 - In numerical processing, the functional role of Spatial-Numerical Associations (SNAs, such as the association of smaller numbers with left space and larger numbers with right space, the Mental Number Line hypothesis) is debated. Most studies demonstrate SNAs with lateralized responses, and there is little evidence that SNAs appear when no response is required. We recorded passive holding grip forces in no-go trials during number processing. In Experiment 1, participants performed a surface numerical decision task (“Is it a number or a letter?”). In Experiment 2, we used a deeper semantic task (“Is this number larger or smaller than five?”). Despite instruction to keep their grip force constant, participants' spontaneous grip force changed in both experiments: Smaller numbers led to larger force increase in the left than in the right hand in the numerical decision task (500–700 ms after stimulus onset). In the semantic task, smaller numbers again led to larger force increase in the left hand, and larger numbers increased the right-hand holding force. This effect appeared earlier (180 ms) and lasted longer (until 580 ms after stimulus onset). This is the first demonstration of SNAs with passive holding force. Our result suggests that (1) explicit motor response is not a prerequisite for SNAs to appear, and (2) the timing and strength of SNAs are task-dependent. (216 words). KW - SNARC KW - Mental number line KW - Number processing KW - Embodied cognition KW - Grip force KW - Motor system Y1 - 2022 U6 - https://doi.org/10.1016/j.actpsy.2022.103791 SN - 1873-6297 VL - 231 SP - 1 EP - 17 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Drago, Claudia A1 - Pawlak, Julia A1 - Weithoff, Guntram T1 - Biogenic aggregation of small microplastics alters their ingestion by a common freshwater micro-invertebrate JF - Frontiers in Environmental Science N2 - In recent years, increasing concerns have been raised about the environmental risk of microplastics in freshwater ecosystems. Small microplastics enter the water either directly or accumulate through disintegration of larger plastic particles. These particles might then be ingested by filter-feeding zooplankton, such as rotifers. Particles released into the water may also interact with the biota through the formation of aggregates, which might alter the uptake by zooplankton. In this study, we tested for size-specific aggregation of polystyrene microspheres and their ingestion by a common freshwater rotifer Brachionus calyciflorus. The ingestion of three sizes of polystyrene microspheres (MS) 1-, 3-, and 6-mu m was investigated. Each MS size was tested in combination with three different treatments: MS as the sole food intake, MS in association with food algae and MS aggregated with biogenic matter. After 72 h incubation in pre-filtered natural river water, the majority of the 1-mu m spheres occurred as aggregates. The larger the particles, the higher the relative number of single particles and the larger the aggregates. All particles were ingested by the rotifer following a Type-II functional response. The presence of algae did not influence the ingestion of the MS for all three sizes. The biogenic aggregation of microspheres led to a significant size-dependent alteration in their ingestion. Rotifers ingested more microspheres (MS) when exposed to aggregated 1- and 3-mu m MS as compared to single spheres, whereas fewer aggregated 6-mu m spheres were ingested. This indicates that the small particles when aggregated were in an effective size range for Brachionus, while the aggregated larger spheres became too large to be efficiently ingested. These observations provide the first evidence of a size- and aggregation-dependent feeding interaction between microplastics and rotifers. Microplastics when aggregated with biogenic particles in a natural environment can rapidly change their size-dependent availability. The aggregation properties of microplastics should be taken into account when performing experiments mimicking the natural environment. KW - microplastics ingestion KW - Brachionus calyciflorus KW - aggregation KW - microplastics KW - polystyrene KW - functional response Y1 - 2020 U6 - https://doi.org/10.3389/fenvs.2020.574274 SN - 2296-665X VL - 8 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Lindner, Nadja A1 - Moeller, Korbinian A1 - Hildebrandt, Frauke A1 - Hasselhorn, Marcus A1 - Lonnemann, Jan T1 - Children's use of egocentric reference frames in spatial language is related to their numerical magnitude understanding JF - Frontiers in Psychology N2 - Numerical magnitude information is assumed to be spatially represented in the form of a mental number line defined with respect to a body-centred, egocentric frame of reference. In this context, spatial language skills such as mastery of verbal descriptions of spatial position (e.g., in front of, behind, to the right/left) have been proposed to be relevant for grasping spatial relations between numerical magnitudes on the mental number line. We examined 4- to 5-year-old’s spatial language skills in tasks that allow responses in egocentric and allocentric frames of reference, as well as their relative understanding of numerical magnitude (assessed by a number word comparison task). In addition, we evaluated influences of children’s absolute understanding of numerical magnitude assessed by their number word comprehension (montring different numbers using their fingers) and of their knowledge on numerical sequences (determining predecessors and successors as well as identifying missing dice patterns of a series). Results indicated that when considering responses that corresponded to the egocentric perspective, children’s spatial language was associated significantly with their relative numerical magnitude understanding, even after controlling for covariates, such as children’s SES, mental rotation skills, and also absolute magnitude understanding or knowledge on numerical sequences. This suggests that the use of egocentric reference frames in spatial language may facilitate spatial representation of numbers along a mental number line and thus seem important for preschoolers’ relative understanding of numerical magnitude. KW - spatial language KW - frames of reference KW - numerical development KW - mental number line KW - preschool children Y1 - 2022 U6 - https://doi.org/10.3389/fpsyg.2022.943191 SN - 1664-1078 SP - 1 EP - 13 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Ogunkola, Moses Olalekan A1 - Guiraudie-Capraz, Gaelle A1 - Féron, François A1 - Leimkühler, Silke T1 - The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells JF - Biomolecules N2 - Sulfur is an important element that is incorporated into many biomolecules in humans. The incorporation and transfer of sulfur into biomolecules is, however, facilitated by a series of different sulfurtransferases. Among these sulfurtransferases is the human mercaptopyruvate sulfurtransferase (MPST) also designated as tRNA thiouridine modification protein (TUM1). The role of the human TUM1 protein has been suggested in a wide range of physiological processes in the cell among which are but not limited to involvement in Molybdenum cofactor (Moco) biosynthesis, cytosolic tRNA thiolation and generation of H2S as signaling molecule both in mitochondria and the cytosol. Previous interaction studies showed that TUM1 interacts with the L-cysteine desulfurase NFS1 and the Molybdenum cofactor biosynthesis protein 3 (MOCS3). Here, we show the roles of TUM1 in human cells using CRISPR/Cas9 genetically modified Human Embryonic Kidney cells. Here, we show that TUM1 is involved in the sulfur transfer for Molybdenum cofactor synthesis and tRNA thiomodification by spectrophotometric measurement of the activity of sulfite oxidase and liquid chromatography quantification of the level of sulfur-modified tRNA. Further, we show that TUM1 has a role in hydrogen sulfide production and cellular bioenergetics. KW - Moco biosynthesis KW - sulfite oxidase KW - cytosolic tRNA thiolation KW - 5-methoxycarbonylmethyl-2-thiouridine KW - H2S biosynthesis KW - cellular bioenergetics Y1 - 2023 U6 - https://doi.org/10.3390/biom13010144 SN - 2218-273X VL - 13 SP - 1 EP - 23 PB - MDPI CY - Basel, Schweiz ET - 1 ER - TY - JOUR A1 - Bertelmann, Roland A1 - Mittermaier, Bernhard A1 - Kostädt, Peter T1 - Transform2Open BT - Kostenmonitoring, Kriterien, Kompetenzen und Prozesse der Open-Access-Transformation Y1 - 2022 U6 - https://doi.org/10.48440/os.helmholtz.054 PB - Helmholtz Open Science Office CY - Potsdam ER - TY - JOUR A1 - Rezori, Roman Enzio von A1 - Buchallik, Friederike A1 - Warschburger, Petra T1 - Validation of the German Benefit Finding Scale for youth with chronic conditions JF - Child and adolescent psychiatry and mental health N2 - Background Benefit finding, defined as perceiving positive life changes resulting from adversity and negative life stressors, gains growing attention in the context of chronic illness. The study aimed at examining the psychometric properties of the Benefit Finding Scale for Children (BFSC) in a sample of German youth facing chronic conditions. Methods A sample of adolescents with various chronic conditions (N = 304; 12 – 21years) completed the 10-item BFSC along with measures of intra- and interpersonal resources, coping strategies, and health-related quality of life (hrQoL). The total sample was randomly divided into two subsamples for conducting exploratory and confirmatory factor analyses (EFA/CFA). Results EFA revealed that the BFSC scores had a one-dimensional factor structure. CFA verified the one-dimensional factor structure with an acceptable fit. The BFSC exhibited acceptable internal consistency (α = 0.87 – 0.88) and construct validity. In line with our hypotheses, benefit finding was positively correlated with optimism, self-esteem, self-efficacy, sense of coherence, and support seeking. There were no correlations with avoidance, wishful thinking, emotional reaction, and hrQoL. Sex differences in benefit finding were not consistent across subsamples. Benefit finding was also positively associated with age, disease severity, and social status. Conclusions The BFSC is a psychometrically sound instrument to assess benefit finding in adolescents with chronic illness and may facilitate further research on positive adaptation processes in adolescents, irrespective of their specific diagnosis. KW - Measure validation KW - Chronic conditions KW - Resilience KW - Coping skills and adjustment KW - Youth Y1 - 2022 U6 - https://doi.org/10.1186/s13034-021-00438-7 SN - 1753-2000 VL - 16 SP - 1 EP - 8 PB - Biomed Central CY - London ER - TY - JOUR A1 - Marggraf, Lara Christin A1 - Lindecke, Oliver A1 - Voigt, Christian C. A1 - Pētersons, Gunārs A1 - Voigt-Heucke, Silke Luise T1 - Nathusius’ bats, Pipistrellus nathusii, bypass mating opportunities of their own species, but respond to foraging heterospecifics on migratory transit flights JF - Frontiers in Ecology and Evolution N2 - In late summer, migratory bats of the temperate zone face the challenge of accomplishing two energy-demanding tasks almost at the same time: migration and mating. Both require information and involve search efforts, such as localizing prey or finding potential mates. In non-migrating bat species, playback studies showed that listening to vocalizations of other bats, both con-and heterospecifics, may help a recipient bat to find foraging patches and mating sites. However, we are still unaware of the degree to which migrating bats depend on con-or heterospecific vocalizations for identifying potential feeding or mating opportunities during nightly transit flights. Here, we investigated the vocal responses of Nathusius’ pipistrelle bats, Pipistrellus nathusii, to simulated feeding and courtship aggregations at a coastal migration corridor. We presented migrating bats either feeding buzzes or courtship calls of their own or a heterospecific migratory species, the common noctule, Nyctalus noctula. We expected that during migratory transit flights, simulated feeding opportunities would be particularly attractive to bats, as well as simulated mating opportunities which may indicate suitable roosts for a stopover. However, we found that when compared to the natural silence of both pre-and post-playback phases, bats called indifferently during the playback of conspecific feeding sounds, whereas P. nathusii echolocation call activity increased during simulated feeding of N. noctula. In contrast, the call activity of P. nathusii decreased during the playback of conspecific courtship calls, while no response could be detected when heterospecific call types were broadcasted. Our results suggest that while on migratory transits, P. nathusii circumnavigate conspecific mating aggregations, possibly to save time or to reduce the risks associated with social interactions where aggression due to territoriality might be expected. This avoidance behavior could be a result of optimization strategies by P. nathusii when performing long-distance migratory flights, and it could also explain the lack of a response to simulated conspecific feeding. However, the observed increase of activity in response to simulated feeding of N. noctula, suggests that P. nathusii individuals may be eavesdropping on other aerial hawking insectivorous species during migration, especially if these occupy a slightly different foraging niche. KW - playback KW - phonotaxis KW - bats KW - acoustic communication KW - animal migration KW - eavesdropping KW - echolocation KW - Pipistrellus nathusii Y1 - 2023 U6 - https://doi.org/10.3389/fevo.2022.908560 SN - 2296-701X SP - 1 EP - 10 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Dörfler, Thomas T1 - Die Sanktionsausschüsse zwischen Macht und Regeln T1 - Sanctions Committees Caught between Power and Rules JF - Vereinte Nationen : Zeitschrift für die Vereinten Nationen und ihre Sonderorganisationen N2 - Sanktionen sind ein wichtiges Instrument des UN-Sicherheitsrats zur Erhaltung des Weltfriedens. Viele zentrale Entscheidungen, wie etwa die Listung und Entlistung terrorverdächtiger Personen, werden fernab der Öffentlichkeit in Sanktionsausschüssen getroffen. Die Einsetzung dieser Ausschüsse hat die Entscheidungsdynamiken im Rat erheblich verändert. N2 - Sanctions are an important instrument of the United Nations Security Council to maintain international peace and security. The Council, however, transfers many decisions, such as the listing and delisting of individuals suspected of supporting terrorism, to its subsidiary sanctions committees, mostly beyond public scrutiny. The article explores, how the creation of sanctions committees has changed decision-making dynamics, how committee members can be committed to rules and what this might imply for Germany’s future role on the Council. KW - Al-Qaida KW - Iran KW - Sanktionen KW - Sicherheitsrat KW - Sudan KW - UN Security Council KW - Terrorismus KW - sanctions committee Y1 - 2018 SN - 0042-384X SN - 2366-6773 VL - 66 IS - 2 SP - 62 EP - 66 PB - BWV CY - Berlin ER - TY - JOUR A1 - Kühne, Franziska A1 - Fauth, Henriette A1 - Destina Sevde, Ay-Bryson A1 - Visser, Leonie N.C. A1 - Weck, Florian T1 - Communicating the diagnosis of cancer or depression: Results of a randomized controlled online study using video vignettes JF - Cancer Medicine N2 - Background Communicating a diagnosis is highly important, yet complex, especially in the context of cancer and mental disorders. The aim was to explore the communication style of an oncologist vs. psychotherapist in an online study. Methods Patients (N = 136: 65 cancer, 71 depression) were randomly assigned to watch a standardized video vignette with one of two communication styles (empathic vs. unempathic). Outcome measures of affectivity, information recall, communication skills, empathy and trust were applied. Results Regardless of diagnosis, empathic communication was associated with the perception of a significantly more empathic (p < 0.001, η2partial = 0.08) and trustworthy practitioner (p = 0.014, η2partial = 0.04) with better communication skills (p = 0.013, η2partial = 0.05). Cancer patients reported a larger decrease in positive affect (p < 0.001, η2partial = 0.15) and a larger increase in negative affect (p < 0.001, η2partial = 0.14) from pre- to post-video than depressive patients. Highly relevant information was recalled better in both groups (p < 0.001, d = 0.61–1.06). Conclusions The results highlight the importance of empathy while communicating both a diagnosis of cancer and a mental disorder. Further research should focus on the communication of a mental disorder in association with cancer. KW - consultation KW - mental health KW - oncology KW - psycho-oncology KW - skills Y1 - 2021 U6 - https://doi.org/10.1002/cam4.4396 SN - 2045-7634 VL - 10 SP - 9012 EP - 9021 PB - Wiley CY - Hoboken, New Jersey, USA ET - 24 ER - TY - JOUR A1 - Minnes, Mark T1 - Más allá de la oscuridad BT - las "Soledades" de Góngora y el pirateo del lenguaje épico durante la primera globalización moderna BT - Góngora’s Soledades and the pirating of epic language during the first modern phase of globalization JF - RILCE : revista de filología hispánica obalización moderna N2 - En los últimos años, la crítica ha vuelto a enfatizar el vínculo de la escritura gongorina la épica y los subgéneros denominados “heroicos” (Mercedes Blanco, Jesús Ponce Cárdenas). Esta nueva perspectiva significa un cambio importante respecto a la recepción del poeta instaurada por la Generación del 27 y en particular por Dámaso Alonso. Limitándose a las Soledades de Góngora, el presente artículo explora las consecuencias de este nuevo paradigma, más allá de un Góngora puramente lírico. Metodológicamente, proponemos dejar atrás la dialéctica idealista o marxista de forma-contenido (la ideología de la forma de Fredric Jameson), por considerarla un enfoque anacrónico en el caso de Góngora. Sin embargo, encontramos un acercamiento filológico viable en el compromiso de la forma del temprano Barthes, que trata de esquivar la dialéctica de forma-contenido y volver a un gesto de escritura (écriture). La hipótesis del presente artículo sería, pues, que no se ha reflexionado suficientemente sobre el gesto de la escritura gongorina en las Soledades: una escritura que piratea el lenguaje épico. N2 - In recent years, literary criticism has begun to emphasize the linkage between Góngoras way of writing and epic or the so-called ‘heroic’ set of subgenres (Mercedes Blanco, Jesús Ponce Cárdenas). This new angle implies a considerable shift in perspective compared to the reception of Góngora by the Generación del 27 and especially Dámaso Alonso. Limiting itself to the Soledades, the present article explores the consequences of this new paradigm, beyond Góngora as a mere ‘lyricist’. From a methodological point of view, we will not rely on the idealist or Marxist dialectic of form and content (the ‘ideology of form’ of Fredric Jameson), which we consider an anachronism when referring to Góngora. Instead, the early Roland Barthes provides an alternative by suggesting the ‘commitment to form’ and attempting to escape the dialectic of form and content through a ‘gesture’ of écriture. Thus, the present article postulates that not enough critical attention has been paid to the ‘gesture’ of Góngoras writing (écriture) in the Soledades: a writing that pirates the language of epic. T2 - Beyond obscurity KW - Luis de Gongora KW - Literary Genres KW - Criticism and Style KW - Semantics of KW - Space KW - Globalization KW - Luis de Góngora KW - Géneros literarios KW - Crítica y estilística KW - Semántica espacial KW - Globaización Y1 - 2020 U6 - https://doi.org/10.15581/008.36.1.387-406 SN - 0213-2370 SN - 2174-0917 VL - 36 IS - 1 SP - 387 EP - 406 PB - Ediciones Universidad de Navarra CY - Pamplona ER - TY - JOUR A1 - Endesfelder, Stefanie A1 - Weichelt, Ulrike A1 - Strauß, Evelyn A1 - Schlör, Anja A1 - Sifringer, Marco A1 - Scheuer, Till A1 - Bührer, Christoph A1 - Schmitz, Thomas T1 - Neuroprotection by caffeine in hyperoxia-induced neonatal brain injury JF - International journal of molecular sciences N2 - Sequelae of prematurity triggered by oxidative stress and free radical-mediated tissue damage have coined the term “oxygen radical disease of prematurity”. Caffeine, a potent free radical scavenger and adenosine receptor antagonist, reduces rates of brain damage in preterm infants. In the present study, we investigated the effects of caffeine on oxidative stress markers, anti-oxidative response, inflammation, redox-sensitive transcription factors, apoptosis, and extracellular matrix following the induction of hyperoxia in neonatal rats. The brain of a rat pups at postnatal Day 6 (P6) corresponds to that of a human fetal brain at 28–32 weeks gestation and the neonatal rat is an ideal model in which to investigate effects of oxidative stress and neuroprotection of caffeine on the developing brain. Six-day-old Wistar rats were pre-treated with caffeine and exposed to 80% oxygen for 24 and 48 h. Caffeine reduced oxidative stress marker (heme oxygenase-1, lipid peroxidation, hydrogen peroxide, and glutamate-cysteine ligase catalytic subunit (GCLC)), promoted anti-oxidative response (superoxide dismutase, peroxiredoxin 1, and sulfiredoxin 1), down-regulated pro-inflammatory cytokines, modulated redox-sensitive transcription factor expression (Nrf2/Keap1, and NFκB), reduced pro-apoptotic effectors (poly (ADP-ribose) polymerase-1 (PARP-1), apoptosis inducing factor (AIF), and caspase-3), and diminished extracellular matrix degeneration (matrix metalloproteinases (MMP) 2, and inhibitor of metalloproteinase (TIMP) 1/2). Our study affirms that caffeine is a pleiotropic neuroprotective drug in the developing brain due to its anti-oxidant, anti-inflammatory, and anti-apoptotic properties. KW - anti-oxidative response KW - caffeine KW - hyperoxia KW - oxidative stress KW - preterm infants KW - developing brain Y1 - 2017 U6 - https://doi.org/10.3390/ijms18010187 SN - 1422-0067 SN - 1661-6596 VL - 18 PB - Molecular Diversity Preservation International CY - Basel ER - TY - JOUR A1 - Reeg, Jette A1 - Strigl, Lea A1 - Jeltsch, Florian T1 - Agricultural buffer zone thresholds to safeguard functional bee diversity BT - Insights from a community modeling approach JF - Ecology and Evolution N2 - Wild bee species are important pollinators in agricultural landscapes. However, population decline was reported over the last decades and is still ongoing. While agricultural intensification is a major driver of the rapid loss of pollinating species, transition zones between arable fields and forest or grassland patches, i.e., agricultural buffer zones, are frequently mentioned as suitable mitigation measures to support wild bee populations and other pollinator species. Despite the reported general positive effect, it remains unclear which amount of buffer zones is needed to ensure a sustainable and permanent impact for enhancing bee diversity and abundance. To address this question at a pollinator community level, we implemented a process-based, spatially explicit simulation model of functional bee diversity dynamics in an agricultural landscape. More specifically, we introduced a variable amount of agricultural buffer zones (ABZs) at the transition of arable to grassland, or arable to forest patches to analyze the impact on bee functional diversity and functional richness. We focused our study on solitary bees in a typical agricultural area in the Northeast of Germany. Our results showed positive effects with at least 25% of virtually implemented agricultural buffer zones. However, higher amounts of ABZs of at least 75% should be considered to ensure a sufficient increase in Shannon diversity and decrease in quasi-extinction risks. These high amounts of ABZs represent effective conservation measures to safeguard the stability of pollination services provided by solitary bee species. As the model structure can be easily adapted to other mobile species in agricultural landscapes, our community approach offers the chance to compare the effectiveness of conservation measures also for other pollinator communities in future. KW - agricultural landscape KW - buffer zones KW - community model KW - functional traits KW - solitary bees KW - spatially explicit Y1 - 2022 U6 - https://doi.org/10.1002/ece3.8748 SN - 2045-7758 VL - 12 SP - 1 EP - 17 PB - Wiley Online Library CY - Hoboken, New Jersey, USA ET - 3 ER - TY - JOUR A1 - Kaunath, Vera A1 - Eccard, Jana T1 - Light Attraction in Carabid Beetles BT - Comparison Among Animals From the Inner City and a Dark Sky Reserve JF - Frontiers in Ecology and Evolution N2 - Artificial light at night (ALAN) is altering the behaviour of nocturnal animals in a manifold of ways. Nocturnal invertebrates are particularly affected, due to their fatal attraction to ALAN. This selective pressure has the potential to reduce the strength of the flight-to-light response in insects, as shown recently in a moth species. Here we investigated light attraction of ground beetles (Coleoptera: Carabidae).We compared among animals (three genera) from a highly light polluted (HLP) grassland in the centre of Berlin and animals collected at a low-polluted area in a Dark Sky Reserve (DSR), captured using odour bait. In an arena setting tested at night time, HLP beetles (n = 75 across all genera) showed a reduced attraction towards ALAN. Tested during daytime, HLP beetles were less active in an open field test (measured as latency to start moving), compared to DSR (n = 143). However, we did not observe a reduced attraction towards ALAN within the species most common at both sides, Calathus fuscipes (HLP = 37, DSR = 118 individuals) indicating that not all species may be equally affected by ALAN. Reduced attraction to ALAN in urban beetles may either be a result of phenotypic selection in each generation removing HLP individuals that are attracted to light, or an indication for ongoing evolutionary differentiation among city and rural populations in their light response. Reduced attraction to light sources may directly enhance survival and reproductive success of urban individuals. However, decrease in mobility may negatively influence dispersal, reproduction and foraging success, highlighting the selective pressure that light pollution may have on fitness, by shaping and modifying the behaviour of insects. KW - light pollution KW - artificial light at night (ALAN) KW - Carabidae beetles KW - environmental change KW - Illuminance KW - solar powered light-emitting diode Y1 - 2022 U6 - https://doi.org/10.3389/fevo.2022.751288 SN - 2296-701X N1 - VK and JE designed the experimental set up and research question. VK performed the animal trapping, experiments and hence, data collection, and organizing of the database. Both authors performed the statistical analyses and contributed to discussion, manuscript revision, read, and approved the submitted version. VL - 10 PB - Frontiers Media CY - Lausanne, Schweiz ER - TY - JOUR A1 - Faber, Eike T1 - Zweimal Kyros BT - die homonymen Perserfürsten und der Kampf um die Macht im Spiegel der Werke des Xenophon (Kyropädie, Anabasis) JF - Potestas : revista de estudios del mundo clásico e historia del arte N2 - «Kyros» taucht als Fürstenname dreimal in der Überlieferung des Perserreiches auf. Der Historiker Xenophon von Athen (427–ca. 355 v. Chr.) hat in seinen Schriften über zwei Träger dieses Namens berichtet und sie durchaus unterschiedlich bewertet: Kyros II. («der Große»), Mehrer des Reiches, sowie ein Jahrhundert später Kyros, Sohn des Dareios und jüngerer Bruder des Perserkönigs Artaxerxes II. Der ältere Kyros ist namengebender Protagonist eines Fürstenspiegels (der Kyropädie), wird also grundsätzlich positiv und als ein Vorbild für andere dargestellt. Am erfolglosen Kampf des jüngeren Kyros um die Krone des Perserreichs hatte Xenophon als Offizier griechischer Söldner selbst teilgenommen. Aus dem Vergleich von Darstellung und Bewertung der beiden Fürsten lassen sich die Ansprüche Xenophons an einen idealen Herrscher ableiten, was hier unternommen werden soll. Zugleich ermöglichen diese Ergebnisse, Xenophon als Historiker und politischen Denker in der zeitgenössischen Debatte um die beste Staatsform einzubetten. N2 - «Cyrus» as the name of a prince occurs thrice in the annals of the Persian Empire. e historian Xenophon of Athens (427–about 355 BC) wrote about two bearers of that name: Cyrus II. («the Great») and, roughly a century later, the younger Cyrus, son of Darius II. and younger brother of Artaxerxes II., the Persian king. e older Cyrus gives his name to a mirror of princes (the Cyrupaedia) and is portrayed positively and as an inspiration to others. Xenophon himself had been an officer in the failed attempt of the younger Cyrus to win the Persian throne by military force. By comparing the way Xenophon depicts and judges both princes, we can deduct what our historian expected of an ideal ruler. ese expectations place Xenophon in the wide contemporary spectrum of opinions on the best constitution (monarchy, oligarchy, democracy). KW - Herodot KW - Xenophon von Athen KW - Kyros II KW - griechische Geschichtsschreibung KW - Altorientalische Monarchie KW - Herodotus KW - Xenophon of Athens KW - Cyrus II KW - Greek Historiography KW - Oriental/Persian Monarchy Y1 - 2016 UR - https://www.e-revistes.uji.es/index.php/potestas/article/view/2308 U6 - https://doi.org/10.6035/potestas.2015.8.2 SN - 1888-9867 SN - 2340-499X IS - 8 SP - 37 EP - 56 PB - Universitat Jaume I CY - Castellón ER - TY - JOUR A1 - Faber, Eike T1 - Macht der Rhetorik - Rhetorik der Macht BT - zum athenischen Epitaphios JF - Potestas : revista de estudios del mundo clásico e historia del arte N2 - ie athenische Totenrede (epitaphios logos) spielte eine Schlüsselrolle bei der Konstruktion des idealisierten Selbstbildes des demokratischen Athen (5./4. Jh.v.Chr.). Dieser Aufsatz zeigt auf, dass die beiden bekanntesten Beispiele für das rhetorische Genre, die Rede des Perikes auf die Gefallenen bei Thukydides und die Rede des Sokrates im platonischen Dialog Menexenos, tatsächlich scharfe Kritik an der Instituton der Totenrede und an der demokratischen Polis an sich üben, obwohl beide Texte für sich betrachtet gemeinhin als affirmativ verstanden werden. N2 - The epitaphios logos played an integral part in the construction of an idealised self-image of democratic Athens (5th / 4th century BC). This paper shows that two famous examples of this rhetorical genre, the orations of Pericles (in the History of the Peloponnesian War by Thucydides) and Socrates (in the Platonic dialogue Menexenos), generally regarded as affirmative, are very critical of the institution and the democratic polis as such. KW - Athen KW - politische Rhetorik KW - Platon KW - Thukydides KW - Athens KW - political rhetoric Y1 - 2009 UR - https://www.e-revistes.uji.es/index.php/potestas/article/view/112 SN - 1888-9867 SN - 2340-499X VL - 2 IS - 2 SP - 117 EP - 132 PB - Universitat Jaume CY - Castellón ER - TY - JOUR A1 - Kaiser, Michaela A1 - Brenne, Andreas T1 - Ästhetik - Normativität - Diversität BT - zum kunstpädagogischen Umgang mit Diversität JF - Individuelle Förderung - Heterogenität und Handlungsperspektiven in der Schule Y1 - 2022 UR - https://elibrary.utb.de/doi/book/10.36198/9783838559193 SN - 978-3-8385-5919-3 SN - 978-3-8252-5919-8 U6 - https://doi.org/10.36198/9783838559193 SP - 249 EP - 259 PB - Waxmann CY - Stuttgart ER - TY - JOUR A1 - Liebe, Thomas A1 - Dordevic, Milos A1 - Kaufmann, Jörn A1 - Avetisyan, Araks A1 - Skalej, Martin A1 - Müller, Notger Germar T1 - Investigation of the functional pathogenesis of mild cognitive impairment by localisation-based locus coeruleus resting-state fMRI JF - Human Brain Mapping N2 - Dementia as one of the most prevalent diseases urges for a better understanding of the central mechanisms responsible for clinical symptoms, and necessitates improvement of actual diagnostic capabilities. The brainstem nucleus locus coeruleus (LC) is a promising target for early diagnosis because of its early structural alterations and its relationship to the functional disturbances in the patients. In this study, we applied our improved method of localisation-based LC resting-state fMRI to investigate the differences in central sensory signal processing when comparing functional connectivity (fc) of a patient group with mild cognitive impairment (MCI, n = 28) and an age-matched healthy control group (n = 29). MCI and control participants could be differentiated in their Mini-Mental-State-Examination (MMSE) scores (p < .001) and LC intensity ratio (p = .010). In the fMRI, LC fc to anterior cingulate cortex (FDR p < .001) and left anterior insula (FDR p = .012) was elevated, and LC fc to right temporoparietal junction (rTPJ, FDR p = .012) and posterior cingulate cortex (PCC, FDR p = .021) was decreased in the patient group. Importantly, LC to rTPJ connectivity was also positively correlated to MMSE scores in MCI patients (p = .017). Furthermore, we found a hyperactivation of the left-insula salience network in the MCI patients. Our results and our proposed disease model shed new light on the functional pathogenesis of MCI by directing to attentional network disturbances, which could aid new therapeutic strategies and provide a marker for diagnosis and prediction of disease progression. KW - attention KW - locus coeruleus KW - mild cognitive impairment KW - resting-state fMRI Y1 - 2022 U6 - https://doi.org/10.1002/hbm.26039 SN - 1097-0193 VL - 43 SP - 5630 EP - 5642 PB - Wiley CY - New York, NY, USA ET - 18 ER -