TY - JOUR A1 - Mani, Deepak A1 - Kupsch, Andreas A1 - Müller, Bernd R. A1 - Bruno, Giovanni T1 - Diffraction Enhanced Imaging Analysis with Pseudo-Voigt Fit Function JF - Journal of imaging : open access journal N2 - Diffraction enhanced imaging (DEI) is an advanced digital radiographic imaging technique employing the refraction of X-rays to contrast internal interfaces. This study aims to qualitatively and quantitatively evaluate images acquired using this technique and to assess how different fitting functions to the typical rocking curves (RCs) influence the quality of the images. RCs are obtained for every image pixel. This allows the separate determination of the absorption and the refraction properties of the material in a position-sensitive manner. Comparison of various types of fitting functions reveals that the Pseudo-Voigt (PsdV) function is best suited to fit typical RCs. A robust algorithm was developed in the Python programming language, which reliably extracts the physically meaningful information from each pixel of the image. We demonstrate the potential of the algorithm with two specimens: a silicone gel specimen that has well-defined interfaces, and an additively manufactured polycarbonate specimen. KW - diffraction enhanced imaging KW - analyzer-based imaging KW - X-ray refraction; KW - non-destructive evaluation KW - Pseudo-Voigt fit function KW - Python Y1 - 2022 U6 - https://doi.org/10.3390/jimaging8080206 SN - 2313-433X VL - 8 IS - 8 PB - MDPI CY - Basel ER - TY - JOUR A1 - Olmer, Ruth A1 - Engels, Lena A1 - Usman, Abdulai A1 - Menke, Sandra A1 - Malik, Muhammad Nasir Hayat A1 - Pessler, Frank A1 - Goehring, Gudrun A1 - Bornhorst, Dorothee A1 - Bolten, Svenja A1 - Abdelilah-Seyfried, Salim A1 - Scheper, Thomas A1 - Kempf, Henning A1 - Zweigerdt, Robert A1 - Martin, Ulrich T1 - Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture JF - Stem Cell Reports N2 - Endothelial cells (ECs) are involved in a variety of cellular responses. As multifunctional components of vascular structures, endothelial (progenitor) cells have been utilized in cellular therapies and are required as an important cellular component of engineered tissue constructs and in vitro disease models. Although primary ECs from different sources are readily isolated and expanded, cell quantity and quality in terms of functionality and karyotype stability is limited. ECs derived from human induced pluripotent stem cells (hiPSCs) represent an alternative and potentially superior cell source, but traditional culture approaches and 2D differentiation protocols hardly allow for production of large cell numbers. Aiming at the production of ECs, we have developed a robust approach for efficient endothelial differentiation of hiPSCs in scalable suspension culture. The established protocol results in relevant numbers of ECs for regenerative approaches and industrial applications that show in vitro proliferation capacity and a high degree of chromosomal stability. KW - virus infection KW - progenitor cells KW - in vitro KW - telomere dysfunction KW - cord blood KW - cardiomyogenic differentiation KW - angiogenesis KW - efficient KW - aberrations KW - expression Y1 - 2017 U6 - https://doi.org/10.1016/j.stemcr.2018.03.017 SN - 2213-6711 VL - 10 IS - 5 PB - Springer CY - New York ER - TY - JOUR A1 - Heger, Tina A1 - Nikles, Gabriele A1 - Jacobs, Brooke S. T1 - Differentiation in native as well as introduced ranges BT - germination reflects mean and variance in cover of surrounding vegetation JF - AoB PLANTS N2 - Germination, a crucial phase in the life cycle of a plant, can be significantly influenced by competition and facilitation. The aim of this study was to test whether differences in cover of surrounding vegetation can lead to population differentiation in germination behaviour of an annual grassland species, and if so, whether such a differentiation can be found in the native as well as in the introduced range. We used maternal progeny of Erodium cicutarium previously propagated under uniform conditions that had been collected in multiple populations in the native and two introduced ranges, in populations representing extremes in terms of mean and variability of the cover of surrounding vegetation. In the first experiment, we tested the effect of germination temperature and mean cover at the source site on germination, and found interlinked effects of these factors. In seeds from one of the introduced ranges (California), we found indication for a 2-fold dormancy, hindering germination at high temperatures even if physical dormancy was broken and water was available. This behaviour was less strong in high cover populations, indicating cross-generational facilitating effects of dense vegetation. In the second experiment, we tested whether spatial variation in cover of surrounding vegetation has an effect on the proportion of dormant seeds. Contrary to our expectations, we found that across source regions, high variance in cover was associated with higher proportions of seeds germinating directly after storage. In all three regions, germination seemed to match the local environment in terms of climate and vegetation cover. We suggest that this is due to a combined effect of introduction of preadapted genotypes and local evolutionary processes. KW - Bet-hedging KW - competition KW - eco-evolutionary experience KW - facilitation KW - genetic adaptation KW - physical and physiological dormancy KW - preadaptation Y1 - 2018 U6 - https://doi.org/10.1093/aobpla/ply009 SN - 2041-2851 VL - 10 IS - 1 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Kolyvushko, Oleksandr A1 - Latzke, Juliane A1 - Dahmani, Ismail A1 - Osterrieder, Nikolaus A1 - Chiantia, Salvatore A1 - Azab, Walid T1 - Differentially-charged liposomes interact with alphaherpesviruses and interfere with virus entry JF - Pathogens N2 - Exposure of phosphatidylserine (PS) in the outer leaflet of the plasma membrane is induced by infection with several members of the Alphaherpesvirinae subfamily. There is evidence that PS is used by the equine herpesvirus type 1 (EHV-1) during entry, but the exact role of PS and other phospholipids in the entry process remains unknown. Here, we investigated the interaction of differently charged phospholipids with virus particles and determined their influence on infection. Our data show that liposomes containing negatively charged PS or positively charged DOTAP (N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium) inhibited EHV-1 infection, while neutral phosphatidylcholine (PC) had no effect. Inhibition of infection with PS was transient, decreased with time, and was dose dependent. Our findings indicate that both cationic and anionic phospholipids can interact with the virus and reduce infectivity, while, presumably, acting through different mechanisms. Charged phospholipids were found to have antiviral effects and may be used to inhibit EHV-1 infection. KW - alphaherpesvirus KW - EHV-1 KW - phosphatidylserine KW - inhibition KW - pathogen host KW - interaction Y1 - 2020 U6 - https://doi.org/10.3390/pathogens9050359 SN - 2076-0817 VL - 9 IS - 5 PB - MDPI CY - Basel ER - TY - JOUR A1 - Michaelis, Vivien A1 - Aengenheister, Leonie A1 - Tuchtenhagen, Max A1 - Rinklebe, Jörg A1 - Ebert, Franziska A1 - Schwerdtle, Tanja A1 - Buerki-Thurnherr, Tina A1 - Bornhorst, Julia T1 - Differences and interactions in placental manganese and iron transfer across an in vitro model of human villous trophoblasts JF - International journal of molecular sciences N2 - Manganese (Mn) as well as iron (Fe) are essential trace elements (TE) important for the maintenance of physiological functions including fetal development. However, in the case of Mn, evidence suggests that excess levels of intrauterine Mn are associated with adverse pregnancy outcomes. Although Mn is known to cross the placenta, the fundamentals of Mn transfer kinetics and mechanisms are largely unknown. Moreover, exposure to combinations of TEs should be considered in mechanistic transfer studies, in particular for TEs expected to share similar transfer pathways. Here, we performed a mechanistic in vitro study on the placental transfer of Mn across a BeWo b30 trophoblast layer. Our data revealed distinct differences in the placental transfer of Mn and Fe. While placental permeability to Fe showed a clear inverse dose-dependency, Mn transfer was largely independent of the applied doses. Concurrent exposure of Mn and Fe revealed transfer interactions of Fe and Mn, indicating that they share common transfer mechanisms. In general, mRNA and protein expression of discussed transporters like DMT1, TfR, or FPN were only marginally altered in BeWo cells despite the different exposure scenarios highlighting that Mn transfer across the trophoblast layer likely involves a combination of active and passive transport processes. KW - manganese KW - iron KW - placental transfer KW - TE interactions KW - BeWo b30 KW - trophoblasts Y1 - 2022 U6 - https://doi.org/10.3390/ijms23063296 SN - 1422-0067 VL - 23 IS - 6 PB - MDPI CY - Basel ER - TY - JOUR A1 - Koelman, Liselot A. A1 - Huybrechts, Inge A1 - Biesbroek, Sander A1 - van 't Veer, Pieter A1 - Schulze, Matthias Bernd A1 - Aleksandrova, Krasimira T1 - Dietary choices impact on greenhouse gas emissions BT - determinants and correlates in a sample of adults from Eastern Germany JF - Sustainability / Multidisciplinary Digital Publishing Institute (MDPI) N2 - The present study estimated diet-related greenhouse gas emissions (GHGE) and land use (LU) in a sample of adults, examined main dietary contributors of GHGE, and evaluated socio demographic, lifestyle, and wellbeing factors as potential determinants of high environmental impact. A cross-sectional design based on data collected from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam cohort (2010-2012) was used. Usual diet was assessed using food frequency questionnaires. Diet-related GHGE and LU were calculated using a European-average lifecycle analyses-food-item database (SHARP-ID). Information on potential determinants were collected using self-administered questionnaires. Men (n = 404) and women (n = 401) at an average age of 66.0 +/- 8.4 years were included. Dietary-related energy-adjusted GHGE in men was 6.6 +/- 0.9 and in women was 7.0 +/- 1.1 kg CO2 eq per 2000 kcal. LU in men was 7.8 +/- 1.2 and in women was 7.7 +/- 1.2 m(2)/year per 2000 kcal. Food groups contributing to most GHGE included dairy, meat and non-alcoholic beverages. Among women, being single, having a job, being a smoker and having higher BMI were characteristics associated with higher GHGE, whereas for men these included being married, longer sleeping duration and higher BMI. Further studies are warranted to provide insights into population-specific determinants of sustainable dietary choices. KW - dietary choices KW - environmental impact KW - greenhouse gas emissions KW - land use KW - determinants Y1 - 2022 U6 - https://doi.org/10.3390/su14073854 SN - 2071-1050 VL - 14 IS - 7 PB - MDPI CY - Basel ER - TY - JOUR A1 - Menzel, Juliane A1 - Longree, Alessa A1 - Abraham, Klaus A1 - Schulze, Matthias Bernd A1 - Weikert, Cornelia T1 - Dietary and plasma phospholipid profiles in vegans and omnivores-results from the RBVD study JF - Nutrients N2 - Over the last few years, the vegan diet has become increasingly popular in Germany. It has been proposed that this diet is generally lower in fat, but less is known about the impact on fatty acid (FA) profiles. Therefore, the cross-sectional "Risks and Benefits of a Vegan Diet" (RBVD) study (n = 72) was used to investigate dietary FA intake as well as plasma phospholipid FA in vegans (n = 36) compared to omnivores (n = 36). Vegans had a significantly lower dietary intake of total fat (median 86 g/day, IQR 64-111) in comparison to omnivores (median 104 g/day, IQR 88-143, p = 0.004). Further, vegans had a lower intake of saturated fatty acids (SFA) (p < 0.0001) and monounsaturated fatty acids (MUFA) (p = 0.001) compared to omnivores. Vegans had a higher intake in total polyunsaturated fatty acids (PUFA), omega-3 and omega-6 PUFA compared to omnivores, but without statistical significance after Bonferroni correction. According to plasma phospholipid profiles, relatively lower proportions of SFA (p < 0.0001), total trans fatty acids (TFA) (p = 0.0004) and omega-3-FA (p < 0.0001), but higher proportions of omega-6-FA (p < 0.0001) were observed in vegans. With the exception of omega-3 PUFA, a vegan diet is associated with a more favorable dietary fat intake and more favorable plasma FA profiles and therefore may reduce cardiovascular risk. KW - SFA KW - TFA KW - MUFA KW - PUFA KW - n-3 fatty acid KW - n-6 fatty acid KW - fatty acids KW - vegan diet Y1 - 2022 U6 - https://doi.org/10.3390/nu14142900 SN - 2072-6643 VL - 14 IS - 14 PB - MDPI CY - Basel ER - TY - JOUR A1 - Weyrich, Alexandra A1 - Jeschek, Marie A1 - Schrapers, Katharina T. A1 - Lenz, Dorina A1 - Chung, Tzu Hung A1 - Ruebensam, Kathrin A1 - Yasar, Sermin A1 - Schneemann, Markus A1 - Ortmann, Sylvia A1 - Jewgenow, Katarina A1 - Fickel, Jörns T1 - Diet changes alter paternally inherited epigenetic pattern in male Wild guinea pigs JF - Environmental Epigenetics N2 - Epigenetic modifications, of which DNA methylation is the most stable, are a mechanism conveying environmental information to subsequent generations via parental germ lines. The paternal contribution to adaptive processes in the offspring might be crucial, but has been widely neglected in comparison to the maternal one. To address the paternal impact on the offspring’s adaptability to changes in diet composition, we investigated if low protein diet (LPD) in F0 males caused epigenetic alterations in their subsequently sired sons. We therefore fed F0 male Wild guinea pigs with a diet lowered in protein content (LPD) and investigated DNA methylation in sons sired before and after their father’s LPD treatment in both, liver and testis tissues. Our results point to a ‘heritable epigenetic response’ of the sons to the fathers’ dietary change. Because we detected methylation changes also in the testis tissue, they are likely to be transmitted to the F2 generation. Gene-network analyses of differentially methylated genes in liver identified main metabolic pathways indicating a metabolic reprogramming (‘metabolic shift’). Epigenetic mechanisms, allowing an immediate and inherited adaptation may thus be important for the survival of species in the context of a persistently changing environment, such as climate change. KW - DNA methylation KW - exposure KW - wild mammal species KW - inheritance KW - plasticity KW - adaptation Y1 - 2018 U6 - https://doi.org/10.1093/eep/dvy011 SN - 2058-5888 VL - 4 IS - 2 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Scholz, Carolin A1 - Voigt, Christian C. T1 - Diet analysis of bats killed at wind turbines suggests large-scale losses of trophic interactions JF - Conservation science and practice N2 - Agricultural practice has led to landscape simplification and biodiversity decline, yet recently, energy-producing infrastructures, such as wind turbines, have been added to these simplified agroecosystems, turning them into multi-functional energy-agroecosystems. Here, we studied the trophic interactions of bats killed at wind turbines using a DNA metabarcoding approach to shed light on how turbine-related bat fatalities may possibly affect local habitats. Specifically, we identified insect DNA in the stomachs of common noctule bats (Nyctalus noctula) killed by wind turbines in Germany to infer in which habitats these bats hunted. Common noctule bats consumed a wide variety of insects from different habitats, ranging from aquatic to terrestrial ecosystems (e.g., wetlands, farmland, forests, and grasslands). Agricultural and silvicultural pest insects made up about 20% of insect species consumed by the studied bats. Our study suggests that the potential damage of wind energy production goes beyond the loss of bats and the decline of bat populations. Bat fatalities at wind turbines may lead to the loss of trophic interactions and ecosystem services provided by bats, which may add to the functional simplification and impaired crop production, respectively, in multi-functional ecosystems. KW - bat fatalities KW - biodiversity decline KW - food web KW - green-green dilemma KW - renewable energy KW - wind energy production KW - wind energy-biodiversity conflict Y1 - 2022 U6 - https://doi.org/10.1111/csp2.12744 SN - 2578-4854 VL - 4 IS - 7 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Guljamow, Arthur A1 - Barchewitz, Tino A1 - Große, Rebecca A1 - Timm, Stefan A1 - Hagemann, Martin A1 - Dittmann, Elke T1 - Diel Variations of Extracellular Microcystin Influence the Subcellular Dynamics of RubisCO in Microcystis aeruginosa PCC 7806 JF - Microorganisms : open access journal N2 - The ubiquitous freshwater cyanobacterium Microcystis is remarkably successful, showing a high tolerance against fluctuations in environmental conditions. It frequently forms dense blooms which can accumulate significant amounts of the hepatotoxin microcystin, which plays an extracellular role as an infochemical but also acts intracellularly by interacting with proteins of the carbon metabolism, notably with the CO2 fixing enzyme RubisCO. Here we demonstrate a direct link between external microcystin and its intracellular targets. Monitoring liquid cultures of Microcystis in a diel experiment revealed fluctuations in the extracellular microcystin content that correlate with an increase in the binding of microcystin to intracellular proteins. Concomitantly, reversible relocation of RubisCO from the cytoplasm to the cell’s periphery was observed. These variations in RubisCO localization were especially pronounced with cultures grown at higher cell densities. We replicated these effects by adding microcystin externally to cultures grown under continuous light. Thus, we propose that microcystin may be part of a fast response to conditions of high light and low carbon that contribute to the metabolic flexibility and the success of Microcystis in the field. KW - cyanobacterial bloom KW - Microcystis KW - microcystin KW - RubisCO KW - extracellular signaling Y1 - 2021 U6 - https://doi.org/10.3390/microorganisms9061265 SN - 2076-2607 VL - 9 IS - 6 PB - MDPI CY - Basel ER - TY - JOUR A1 - Weiß, Norman A1 - Lanzl, Theresa T1 - Die wechselvolle Geschichte der Mitgliedschaft Russlands im Europarat JF - Zeitschrift für ausländisches öffentliches Recht und Völkerrecht N2 - Der russische Angriffskrieg auf die Ukraine hat auch die Europäische Menschenrechtsarchitektur ins Wanken gebracht. Der Europarat reagierte schnell und beendete die Mitgliedschaft der Russischen Föderation. Aus diesem Anlass blickt der Beitrag zurück auf die wechselvolle Geschichte der Mitgliedschaft Russlands im Europarat. Seit dem Beitritt vor 26 Jahren haben Konfrontationen die – oftmals kurzen– Phasen der Kooperation überschattet. Das wirft die Frage auf, inwieweit die „Politik des Dialogs“ gegenüber der Russischen Föderation geeignet war, die Menschenrechtslage in Russland zu verbessern. Der Beitrag legt zudem die rechtlichen Grundlagen von Beitritt und Ende der Mitgliedschaft dar und untersucht, wie sich der Ausschluss auf die Anwendbarkeit der Europäischen Menschenrechtskonvention (EMRK) auswirkt. Der Ausschluss Russlands stellt einen Wendepunkt dar. Zwar wird damit ein potenziell gefährlicher Präzedenzfall geschaffen. Jedoch entsteht durch die geschlossene Reaktion der restlichen Mitgliedstaaten auch ein Momentum für Reformen und eine Rückbesinnung auf das Gründungsziel des Europarates – die kollektive Durchsetzung der Menschenrechte. N2 - The Russian war of aggression on Ukraine has also shaken the European human rights architecture. The Council of Europe reacted quickly and terminated the Russian Federation's membership. On this occasion, the article looks back at the chequered history of Russia's membership in the Council of Europe. Since its accession 26 years ago, confrontations have overshadowed the - often brief - phases of cooperation. This raises the question of the extent to which the "policy of dialogue" towards the Russian Federation was suitable for improving the human rights situation in Russia. The article also sets out the legal basis for accession and the end of membership and examines how the exclusion affects the applicability of the European Convention on Human Rights (ECHR). Russia's exclusion represents a turning point. To be sure, it sets a potentially dangerous precedent. However, the united response of the remaining member states also creates momentum for reform and a return to the founding purpose of the Council of Europe - the collective enforcement of human rights. KW - Europarat KW - Russische Föderation KW - Ende der Mitgliedschaft Y1 - 2023 U6 - https://doi.org/10.17104/0044-2348-2022-4-801 SN - 0044-2348 SN - 0172-4770 VL - 82 IS - 4 SP - 801 EP - 829 PB - Nomos CY - Baden-Baden ER - TY - JOUR A1 - Carlà-Uhink, Filippo T1 - Die Tabula Traiana und Drăgans Decebalus: symbolische Auseinandersetzungen zwischen Serbien und Rumänien an der Donau JF - thersites N2 - Since 2004 a giant portrait of the ancient Dacian king Decebalus can be seen by people visiting the Đerdap national park in Serbia or sailing along the Danube. The location is carefully chosen: the ancient king is located on the other side of the river, within the Romanian Parcul Natural Porțile de Fier, but is carved in the rock so to look in the direction from where, at the beginning of the 2nd century CE, the Romans came to move war to him and his people. Not by chance, on the Serbian side of the river and not far away from the sculpture is the Tabula Traiana, a Roman inscription celebrating the opening of the Roman road leading here in 100 CE. This article moves from the role of ancient Rome in the historical cultures and national identities of the two countries facing each other here, Serbia and Romania, in order to explain how the Romans represented a ‘contested identity’ and therefore why, at the end of the 20th century, the Romanian nationalistic millionaire G. C. Drăgan decided to invest a humongous quantity of money in the realization of the sculpture of Decebalus. KW - Trajan KW - Tabula Traiana KW - Iron Gates KW - Serbia KW - Romania KW - Drăgan KW - Thracians KW - Dacians KW - Decebalus Y1 - 2020 U6 - https://doi.org/10.34679/thersites.vol10.101 VL - 2019 IS - 10 SP - 94 EP - 127 ER - TY - JOUR A1 - Trilcke, Peer T1 - Die Spatzen quirilierten auf den Telegraphendrähten BT - Vorwort JF - Fontanes Medien Y1 - 2022 SN - 978-3-11-073323-5 SN - 978-3-11-073810-0 SN - 978-3-11-073330-3 U6 - https://doi.org/10.1515/9783110733235-001 SP - XI EP - XIII PB - de Gruyter CY - Berlin ER - TY - JOUR A1 - Dörfler, Thomas T1 - Die Sanktionsausschüsse zwischen Macht und Regeln T1 - Sanctions Committees Caught between Power and Rules JF - Vereinte Nationen : Zeitschrift für die Vereinten Nationen und ihre Sonderorganisationen N2 - Sanktionen sind ein wichtiges Instrument des UN-Sicherheitsrats zur Erhaltung des Weltfriedens. Viele zentrale Entscheidungen, wie etwa die Listung und Entlistung terrorverdächtiger Personen, werden fernab der Öffentlichkeit in Sanktionsausschüssen getroffen. Die Einsetzung dieser Ausschüsse hat die Entscheidungsdynamiken im Rat erheblich verändert. N2 - Sanctions are an important instrument of the United Nations Security Council to maintain international peace and security. The Council, however, transfers many decisions, such as the listing and delisting of individuals suspected of supporting terrorism, to its subsidiary sanctions committees, mostly beyond public scrutiny. The article explores, how the creation of sanctions committees has changed decision-making dynamics, how committee members can be committed to rules and what this might imply for Germany’s future role on the Council. KW - Al-Qaida KW - Iran KW - Sanktionen KW - Sicherheitsrat KW - Sudan KW - UN Security Council KW - Terrorismus KW - sanctions committee Y1 - 2018 SN - 0042-384X SN - 2366-6773 VL - 66 IS - 2 SP - 62 EP - 66 PB - BWV CY - Berlin ER - TY - JOUR A1 - Wienfort, Monika ED - Wienfort, Monika T1 - Die Preußische Seehandlung im Lexikon im 19. Jahrhundert JF - Die Preußische Seehandlung zwischen Markt, Staat und Kultur : 40 Jahre Stiftung Preußische Seehandlung N2 - Im 19. Jahrhundert waren Konversationslexika, wie der Name schon andeutet, dazu gedacht, die Konversation in Salon und Vereinen mit Informationen zu bereichern. In den einzelnen Artikeln wurde auf Präzision, Genauigkeit und Überprüfbarkeit gesetzt, um der Leserschaft auch ein eigenes Urteil zu ermöglichen. Die „Seehandlungs-Societät in Preußen“ oder „Seehandlung, preußische“, wie sie in deutschen Lexika vorkommt, wandelte sich im 19. Jahrhundert zur Staatsbank. In der ersten Hälfte des 19. Jahrhunderts fielen die Urteile der Lexika meist ablehnend aus: Die Seehandlung erschien als eine wirtschaftspolitisch katastrophale Fehlentwicklung. Eine besondere Rolle spielte der Präsident Christian (von) Rother, der die Seehandlung zum selbständigen Unternehmen gemacht hatte. Der Wandel der allgemeinen Lexika in der zweiten Hälfte des 19. Jahrhunderts veränderte auch die Sicht auf die Seehandlung. Die Geschäfte der Bank wurden positiv hervorgehoben, die Beurteilungen verwiesen auf Statistiken und Bilanzen. Der Fokus rückte von den leitenden Personen der Seehandlung hin zum Kampf um Handelsmonopole und den preußischen Landtag als öffentlichem Forum. Das vernichtende Urteil der ersten Hälfte des 19. Jahrhunderts war einer differenzierten Bewertung der Bankentätigkeit gewichen. N2 - In the 19th century, German Konversationslexika, as the name suggests, were intended to help with conversation in salons and private clubs for an educated public. Precision, accuracy and verifiability were emphasised in the descriptions of these works in order to enable the readership to come to comprehensive conclusions. Eventually, the Seehandlung was transformed into a state bank. During the first half of the 19th century, judgements by the encyclopedias tended to be quite negative, and the Seehandlung was portrayed as an economic-political catastrophe, severely damaging commerce. Particularly frequent reference was made to president Christian Rother, who was mainly responsible for turning the Seehandlung into an independent company. In the second half of the 19th century, public perception was thoroughly altered. By referring to statistics and balance sheets, the characteristics of the bank were emphasized. The focus of many articles shifted away from the leading figures onto the fight against trade monopolies and to the Prussian parliament as decisive actor. The scathing judgement about the Seehandlung of the first half of the 19th century was gradually replaced by a differentiated assessment of the bank’s activity. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-599907 SN - 978-3-86956-562-0 SP - 129 EP - 150 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Wieber, Anja ED - Ambühl, Annemarie T1 - Die palmyrenische Königin Zenobia als Werbeikone für Seife JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien = Transformative Translations in Jewish History and Culture N2 - This article analyses, as an example of the advertising of cosmetic products, a campaign launched by the US-American company “Johnson Soap” for their product, the facial soap “Palmolive”. Examining its ads of 1911 in which certain ancient exempla are employed, it becomes clear that the Palmyrene queen Zenobia and with her the semi-historical Semiramis and the more mythical Dido are aligned to the “1001 Nights” character Scheherazade. Since they are jointly labelled as “historically famous oriental queens” and because of the reference to Zenobia’s white skin, they fall into the fantasy of fair-skinned harem women and evoke thoughts of all the pleasures and comforts of the luxurious Orient. To the modern female customer of 1900 (well steeped in the knowledge of those ancient characters) Zenobia and the other exempla should serve as celebrities worth emulating. Above all they are deemed to be beautiful, and experts in cosmetics which would guarantee the effect of the product they are standing for. A finding that proves to be valid even in an advertising concept of today for the Syrian-German “Zhenobya-soap”. KW - Zenobia KW - classical reception KW - advertising (cosmetics, USA, ca. 1900) KW - orientalism KW - racist subtext KW - Dido KW - Semiramis KW - Scheherazade KW - Cleopatra Y1 - 2020 U6 - https://doi.org/https://doi.org/10.34679/thersites.vol11.169 SN - 2364-7612 VL - 2020 IS - 11 SP - 277 EP - 323 ER - TY - JOUR A1 - Yaldiz, Yunus T1 - Die Muslime Berlins und Brandenburgs BT - Diplomatische Beziehungen, islamische Bauten, Kriegsgefangene, Propaganda im Umfeld des Ersten Weltkriegs JF - Hier geblieben? Brandenburg als Einwanderungsland vom Mittelalter bis heute Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-546843 SN - 978-3-86956-506-4 SP - 177 EP - 192 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Ette, Ottmar ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - Die Listen Alexander von Humboldts BT - Zur Epistemologie einer Wissenschaftspraxis JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Es gibt Hunderte, ja Tausende von Listen und Auflistungen im wissenschaftlichen Schaffen Alexander von Humboldts. Sie fügen sich ein in die diskontinuierliche Schreibweise des preußischen Forschers und sind in vielerlei Hinsicht nicht nur wie seine Schriften selbst als vielsprachig, sondern auch als viellogisch zu bezeichnen. Sie repräsentieren Schreibformen, auf welche Humboldt in seinen Amerikanischen Reisetagebüchern als dem wohl besten Zugang zu seinem Denk-, Schreib- und Wissenschaftsstil, aber auch in seinen gedruckten wissenschaftlichen Abhandlungen häufig zurückgriff. Es sind Listen einer Epistemologie ständiger Erweiterung. Sie markieren den Beginn einer transdisziplinären Wissenschaft, die von ihrer Aktualität nichts verloren hat. In unseren Zeiten ökologischer Katastrophen braucht es ein Denken, das unseren Planeten Erde in all seinen Zusammenhängen und Wechselwirkungen erschließt und Sorge dafür trägt, die verschiedenartigen Einwirkungen der Kulturen der Welt auf die Natur nicht länger zu vernachlässigen. N2 - Il existe des centaines, voire des milliers de listes et de listages dans les travaux scientifiques dʼAlexander von Humboldt. Ils sʼinscrivent dans le style d'écriture discontinu du chercheur prussien et peuvent être décrits à bien des égards non seulement comme multilingues, comme ses écrits eux-mêmes, mais aussi comme polylogiques. Ils représentent des formes dʼécriture que Humboldt a souvent utilisées dans ses carnets de voyage américains, probablement le meilleur accès à son style de pensée, dʼécriture et de recherche, mais aussi dans ses traités scientifiques imprimés. Ce sont des listes dʼune épistémologie en constante expansion. Les listes de Humboldt marquent le début d'une science transdisciplinaire qui n'a rien perdu de son actualité. En ces temps de catastrophes écologiques, nous avons besoin dʼun mode de pensée qui ouvre notre planète Terre dans tous ses contextes et interactions et qui fasse en sorte que les diverses influences des cultures du monde sur la nature ne soient plus négligées. N2 - There are hundreds, even thousands of lists and listings in the scientific work of Alexander von Humboldt. They fit into the discontinuous style of writing of the Prussian researcher and in many respects can be described not only as multilingual, like his writings themselves, but also as polylogical. They represent forms of writing that Humboldt often used in his American Travel Diaries, probably the best access to his style of thinking, writing and research, but also in his printed scientific treatises. They are lists of an epistemology of constant expansion. Humboldtʼs lists mark the beginning of a transdisciplinary science that has lost none of its topicality today. In our times of ecological catastrophes, we need a way of thinking that opens up our planet Earth in all its contexts and interactions and ensures that the various influences of the world's cultures on nature are no longer neglected. KW - Epistemologie der Erweiterung KW - Listen KW - Amerikanische Reisetagebücher KW - Tableau Physique KW - Vues des Cordillères Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-488342 SN - 2568-3543 SN - 1617-5239 VL - XXI IS - 41 SP - 43 EP - 61 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Allgaier-Honal, Recha T1 - Die Laubhütte im Spiegel eines Minhagim-Buches – ein Fragment aus der Genisa Reckendorf JF - Genisa-Blätter IV Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-584882 SN - 978-3-86956-539-2 SP - 61 EP - 72 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Zauke, Svenja A1 - Neumann, Sandra T1 - Die kommunikative Partizipation von Kindern mit Sprachentwicklungsstörungen im Vorschulalter: erste Daten mit dem FOCUS©-34-G JF - Spektrum Patholinguistik 16 N2 - Bei Kindern mit Sprachentwicklungsstörungen (SES) können sich Symptome auf sprachlich-funktionaler Ebene sehr variabel auf die kommunikative Partizipation im Alltag auswirken. Kommunikative Partizipation wird definiert als sprachlich-kommunikatives Teilnehmen an Lebenssituationen, in denen Wissen, Informationen, Ideen oder Gefühle ausgetauscht werden. Der deutschsprachige ‚Fokus auf den Erfolg der Kommunikation für Kinder unter sechs Jahren‘ (FOCUS©-34-G) ist ein evaluierter Fragebogen zur Fremdeinschätzung der kommunikativen Partizipation von Kindern (1;6 bis 5;11 Jahre). Ziel unserer Studie war die Untersuchung der Auswirkungen einer SES auf die kommunikative Partizipation betroffener Kinder im Alter zwischen 2;0 und 4;11 Jahren anhand des FOCUS©-34-G. Eltern von Kindern mit SES füllten den FOCUS©-34-G sowie einen Demografie-Bogen aus. Es konnten erste Daten von 22 Kindern (16 Jungen) im Alter zwischen 2;7 und 3;11 (M = 3;3 Jahre, SD = 0;4 Jahre) erhoben werden. Im FOCUS©-34-G erreichten Kinder mit SES einen Gesamtwert zwischen 54 und 197 (M = 120.55, SD = 40.91) von 238 maximal möglichen Punkten. Diese Ergebnisse zeigen eine eingeschränkte kommunikative Partizipation von Kindern mit SES, die es in einer ICF-CY-orientierten sprachtherapeutischen Intervention zu beachten gilt. Als klinisches Assessmentinstrument kann der FOCUS©-34-G als Kurzversion des FOCUS©-G als geeignet angesehen werden. KW - kommunikative Partizipation KW - Sprachentwicklungsstörung KW - SES KW - ICF-CY KW - Vorschulalter Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-613489 SN - 978-3-86956-559-0 SN - 1866-9433 SN - 1869-3822 IS - 16 SP - 117 EP - 133 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Sancı, Kadir A1 - Kardas, Arhan ED - Kollodzeiski, Ulrike ED - Hafner, Johann Evangelist T1 - Die islamische Speiseordnung BT - Alles ḥalāl oder ḥarām? JF - Du sollst nicht essen: Warum Menschen auf Nahrung verzichten – interdisziplinäre Zugänge Y1 - 2024 SN - 978-3-98740-007-0 SN - 978-3-98740-008-7 U6 - https://doi.org/10.5771/9783987400087 SP - 105 EP - 124 PB - Ergon Verlag CY - Baden-Baden ER - TY - JOUR A1 - Zaruba, Nicole A1 - Gronostaj, Anna A1 - Ahlgrimm, Frederik A1 - Vock, Miriam T1 - Die Entwicklung von Lehrkräfteüberzeugungen im Praxissemester BT - Welche Lerngelegenheiten sind aus Studierendensicht relevant? JF - Professionalisierung in Praxisphasen : Ergebnisse der Lehrerbildungsforschung an der Universität Potsdam (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 2) N2 - Überzeugungen zum Lehren und Lernen sind als Teil der professionellen Kompetenz von Lehrkräften bereits im Lehramtsstudium relevant und haben insbesondere in längeren Praxisphasen Entwicklungspotenzial. Welche Faktoren für die Entwicklung von Überzeugungen in Praxisphasen von Bedeutung sind, ist bislang aber nur unzureichend erforscht. In Interviews haben wir N = 16 Studierende befragt, welche Lerngelegenheiten für die Entwicklung ihrer Überzeugungen im Praxissemester eine Rolle spielten. Dabei konnten wir mittels Inhaltsanalyse vier übergeordnete Faktoren identifizieren: die universitäre Lernbegleitung, die Mentorinnen und Mentoren, die Schülerinnen und Schüler und die Reflexion eigener Unterrichtserfahrungen. Den Faktoren wurden untergeordnete Faktoren (z. B. Hospitationen durch Universitätsdozierende) zugeordnet und es wird dargestellt, warum und unter welchen Umständen diese Lerngelegenheiten für die Entwicklung der Überzeugungen aus Studierendensicht relevant sind. N2 - Beliefs about teaching and learning are part of a teacher’s professional competence. They should, thus, already be considered in teacher preparation as they can evolve, especially in the context of field experience. However, research on the factors that influence the development of teachers’ beliefs during school placement is sparse. We asked N = 16 preservice teachers which learning opportunities they considered relevant for the development of their beliefs in the Praxissemester. Using qualitative content analysis, we identified four main factors: university support, mentors in schools, pupils, and reflection on teaching experiences. We assigned subordinate factors (e. g. accompanying seminars) to the main factors. Subsequently, we describe why and under which circumstances these learning opportunities are relevant for the development of beliefs from the preservice teachers’ point of view. Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-570839 SN - 978-3-86956-508-8 SN - 2626-3556 SN - 2626-4722 IS - 2 SP - 215 EP - 234 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Martini, Annett T1 - Die Buchstabenkrönchen als Erinnerungsanker der Josefsgeschichte BT - Auf den Spuren eines mittelalterlichen Torarollenfragments JF - Genisa-Blätter IV Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-584878 SN - 978-3-86956-539-2 SP - 43 EP - 60 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Reich, Karin ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - Die Beziehungen zwischen Alexander von Humboldt und Hans Christian Ørsted BT - Treffen, Briefwechsel JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Hans Christian Ørsted gehörte zu den bedeutendsten Physikern seiner Zeit, er und Michael Faraday waren die Schöpfer des Elektromagnetismus. Ein erstes Treffen zwischen Alexander von Humboldt und Oersted fand im Frühjahr 1823 in Paris statt. Weitere Treffen folgten in Altona bzw. Hamburg im Jahr 1827, in Berlin 1828, in Berlin und Potsdam 1843 sowie in Kopenhagen 1845. Die erhaltenen Briefe – zwei Briefe von Humboldt an Ørsted sowie zwei Briefentwürfe von Oersted an Humboldt – gewähren weitere Einblicke in das gute Verhältnis, das diese beiden Wissenschaftler miteinander pflegten. Obwohl Ørsted eines der treuesten Mitglieder des Göttinger Magnetischen Vereins war und beste Beziehungen zu Gauß und Weber unterhielt, spielten im „Kosmos“ Ørsteds Beiträge zum Erdmagnetismus keine Rolle, hier wurden nur Ørsteds Beiträge zum Elektromagnetismus gewürdigt. N2 - Hans Christian Ørsted was one of the most famous physicists of his time, he and Michael Faraday founded the new discipline electromagnetism. A first meeting between Alexander von Humboldt and Ørsted took place in Paris in spring 1823. Several other meetings followed, 1827 in Altona respectively Hamburg, 1828 in Berlin, 1843 in Berlin and Potsdam and 1845 in Kopenhagen. The still existing four letters, two letters from Humboldt to Ørsted and two drafts from Ørsted to Humboldt, give an insight into the relationship, the two scientists were on good terms. Though Ørsted was one of the most important members of the Göttinger Magnetic Association and a real friend of Gauss and Weber, Ørsted’s contributions to terrestrial magnetism played no role in the „Kosmos“, there Humboldt admired only Ørsted’s contributions to electromagnetism. N2 - Hans Christian Ørsted était un des plus fameux physiciens de son temps. Lui est Michael Faraday ont établi la nouvelle discipline électromagnétisme. Au printemps de l’année 1823 Alexander von Humboldt et Ørsted se sont rencontrés pour la première fois à Paris. Plusieurs autres rencontres suivaient, à Altona ou à Hambourg en 1827, à Berlin en 1828, à Berlin ou Potsdam en 1843 et à Copenhague en 1845. Les quatre lettres conserves, deux lettres de Humboldt à Ørsted et deux esquisses de Oersted à Humboldt, illustrent la bonne relation entre les deux savants. Quoique Ørsted fût en des membres les plus importants de l’Association Magnétique de Gottingue“ et un ami étroit de Gauss et de Weber, ses contributions au magnétisme terrestre ne jouaient pas de role dans le „Cosmos“, Humboldt n’y admirait que les contributions de Ørsted à l’électromagnétisme. KW - Christian VIII. KW - Copley-Medaille KW - Elektromagnetismus KW - Erdmagnetismus KW - Friedrich Wilhelm IV. KW - Göttinger Magnetischer Verein KW - Humboldtscher Magnetischer Verein KW - Magnetisches Observatorium KW - Orden Pour le Mérite KW - Hans Christian Ørsted Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-592381 SN - 2568-3543 SN - 1617-5239 VL - XXIII IS - 45 SP - 73 EP - 96 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Kraft, Tobias T1 - Die Berliner "Edition Humboldt digital" JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Das Akademienvorhaben „Alexander von Humboldt auf Reisen – Wissenschaft aus der Bewegung“ (AvH-R) hat Anfang 2015 mit einer projektierten Laufzeit von 18 Jahren seine Arbeit an der Berlin-Brandenburgischen Akademie der Wissenschaften aufgenommen. Die Hauptaufgabe von AvH-R besteht in der vollständigen Herausgabe der Humboldt‘schen Manuskripte zum Themenkomplex Reisen an der Schnittstelle von Kultur- und Naturwissenschaften. Die Schriftenreihe des Akademienvorhabens AvH-R läuft unter dem Titel Edition Humboldt und ist hybrid angelegt. Die Printedition der Tagebücher – Edition Humboldt – ist als Lesefassung konzipiert. Die Edition Humboldt digital zielt auf eine möglichst umfassende textorientierte Transkription und Kommentierung der Handschriften sowie auf eine intelligente Nutzung normdateibasierter Webdienste und Informationsangebote. Die ersten Ergebnisse wurden im Herbst 2016 der Öffentlichkeit unter avhr.bbaw.de präsentiert und werden hier zusammengefasst vorgestellt. N2 - The Academy Project „Alexander von Humboldt auf Reisen – Wissenschaft aus der Bewegung [Travelling Humboldt – Science on the Move]“ (AvH-R) started in 2015 at the Berlin Brandenburg Academy of Sciences and Humanities and has a project lifetime of 18 vears. Its main focus is the edition of Humboldt’s manuscripts on the topical complex ‘journeys’ at the intersection of cultural and natural sciences. The project’s series is designed as a hybrid edition under the title Edition Humboldt. Its print version is made for reading, while Edition Humboldt digital offers complete transcriptions, a critical apparatus and the intelligent use of digital components and interfaces. AvH-R’s first results were shown to the public in autumn of 2016 under avhr.bbaw.de and are presented here in a summarized version. N2 - El proyecto de academia „Alexander von Humboldt auf Reisen – Wissenschaft aus der Bewegung [Centro Alejandro de Humboldt – Ciencia en Movimiento]“ (AvH-R) empezó en 2015 en la Academia de Ciencias y Humanidades de Berlín Brandenburgo y tiene una duración estimada de 18 años. Su enfoque principal es la edición de los manuscritos de viaje humboldtianos en la intersección de ciencias naturales y culturales. La edición del proyecto bajo el título de Edition Humboldt tiene un diseño híbrido. Su versión impresa estará hecha para la lectura principalmente, mientras que Edition Humboldt digital ofrecerá transcripciones completas con apendices críticos y el uso inteligente de componentes e interfaces digitales. Los primeros resultados del trabajo de AvH-R se presentaron al público en otoño de 2016 bajo avhr.bbaw.de y son sintetizados aquí para su mayor difusión. KW - Editionsphilologie KW - Akademienvorhaben "Alexander von Humboldt auf Reisen - Wissenschaft aus der Bewegung KW - Nachlass Alexander von Humboldt Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-395747 SN - 1617-5239 SN - 2568-3543 VL - XVIII IS - 34 SP - 3 EP - 16 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Lauer, Norina A1 - Corsten, Sabine T1 - Die Bedeutung von Peers für die soziale Teilhabe von Menschen mit Aphasie JF - Spektrum Patholinguistik 16 N2 - Menschen mit Aphasie erleben erhebliche Einbußen in sozialer Teilhabe und Lebensqualität. Peer-to-Peer-Unterstützung durch Selbsthilfeangebote oder Peer-Befriending-Maßnahmen kann sich positiv auf Partizipation und psychisches Wohlbefinden auswirken. Mit dem Projekt shalk konnte gezeigt werden, dass von Betroffenen geleitete Selbsthilfegruppen maßgeblich zu Selbstwerterleben und verbesserter Lebensqualität der Leitungspersonen und der Gruppenteilnehmenden beitragen können. Um einen Austausch zwischen Betroffenen auch jenseits des Gruppensettings zu ermöglichen, können digitale Medien genutzt werden. Im Projekt PeerPAL wird ein für Menschen mit Aphasie angepasstes digitales soziales Netzwerk (Smartphone-App) zur virtuellen Vernetzung und persönlichen Begegnung entwickelt und evaluiert. Erste Daten weisen darauf hin, dass die Betroffenen die App nutzen können und mit Design und Funktionen zufrieden sind. Auswirkungen auf die Lebensqualität werden aktuell untersucht. Sprachtherapeut:innen nehmen in der Peer-to-Peer-Unterstützung insofern eine zentrale Rolle ein, als dass sie Betroffene in entsprechende Angebote einführen und sie mittels abgestufter Begleitung an die eigenständige Nutzung heranführen. KW - Aphasie KW - Lebensqualität KW - Selbsthilfe KW - Peer-Befriending KW - digitales soziales Netzwerk Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-613404 SN - 978-3-86956-559-0 SN - 1866-9433 SN - 1869-3822 IS - 16 SP - 15 EP - 37 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Grahovac, Tena T1 - Die Basalganglien bei der Lautstärkeverarbeitung JF - Spektrum Patholinguistik 16 N2 - Der neurodegenerativen Erkrankung Morbus Parkinson (MP) liegt der Zerfall von Neuronen in den Basalganglien (BG) zugrunde, der mitunter zu kognitiv-sprachlichen Einschränkungen führt. Dies betrifft beispielsweise die Lautstärkeproduktion und -wahrnehmung. Betroffene sprechen signifikant leiser und weisen eine verringerte Wahrnehmungsspanne für Lautstärke auf. Dieses Wahrnehmungsdefizit und die Tatsache, dass die BG die betroffene neurologische Struktur bei MP sind, lässt eine Beteiligung dieser bei der Lautstärkeverarbeitung von Gesunden vermuten. Um die Rolle der BG bei der Lautstärkeverarbeitung zu untersuchen, wurde eine generalisierte lineare Modellanalyse durchgeführt. Anhand von fMRT-Daten von gesunden Proband*innen, erhoben von Erb et al. (2020), wurde nach linearen Regressionen zwischen den präsentierten Lautstärkewerten und dem BOLD-Signal in acht BG-Regionen gesucht. Hierfür wurden Daten von 63 Proband*innen im Alter zwischen 18 und 78 Jahren (Durchschnitt: 43,4 Jahre) genutzt. Im linken und rechten Putamen angrenzend zum Globus pallidus pars externa war eine positive lineare Regression beobachtbar. Eine negative lineare Regression zeigte sich im Kopf des Nucleus caudatus beider Hemisphären. Teile der BG scheinen somit möglicherweise eine Rolle bei der Verarbeitung von Lautstärke zu spielen. In Bezug auf MP besteht die Möglichkeit, dass ihre neuronale Degeneration mitursächlich für die Wahrnehmungseinschränkungen ist. Dies sowie der Einfluss dieses rezeptiven Lautstärkedefizits auf die produktiven sprachlichen Einschränkungen sollten Gegenstand zukünftiger Untersuchungen sein. Es ist gut möglich, dass die Ursache der produktiven Lautstärkedefizite nicht motorischer, sondern rezeptiver Natur ist. Dies hätte einen großen Einfluss auf künftige sprachtherapeutische Konzepte bei der Behandlung produktiver Sprachstörungen bei MP. KW - Morbus Parkinson KW - Basalganglien KW - Lautstärkeverarbeitung KW - Dysarthrie Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-613599 SN - 978-3-86956-559-0 SN - 1866-9433 SN - 1869-3822 IS - 16 SP - 219 EP - 234 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Partenheimer, Lutz T1 - Die Ansiedlungspolitik der Markgrafen von Brandenburg aus dem Hause der Askanier JF - Hier geblieben? Brandenburg als Einwanderungsland vom Mittelalter bis heute Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-546539 SN - 978-3-86956-506-4 SP - 49 EP - 63 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Bredekamp, Horst T1 - Die Amerikanischen Reisetagebücher BT - ein erster Zugang JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Die Reisetagebücher der Amerika-Reise (1799-1804) stellen ein Kompendium an schriftlichen Einträgen, Tabellen, Diagrammen und Zeichnungen dar, das in der Tradition römischer Papiermuseen des 17. Jhs. steht. Sie können als Mikrokosmen kleiner Kunstkammern aufgefasst werden, in denen Naturobjekte, Kunstwerke und Arbeitsmittel einen gemeinsamen Reflexionsraum bilden. Im Zentrum des vorliegenden Beitrags steht Humboldts Auffassung einer gestalteten Bestimmung von Landschaft vermittels besonders einprägsamer Bildformen. Auf erstaunliche Weise nähert sich Humboldts Ästhetik der Gesamtsicht von Natur Charles Darwins Begriff der natürlichen Schönheit an. In den Reisetagebüchern zeigt sich ein heterogener, von Lebendigkeit zeugender Charakter, der sowohl durch das unterschiedliche Format der einzelnen Hefte, als auch durch die inkonsistente Behandlung des Papiers erreicht wird. Dieser bewegliche Zug setzt sich in zahlreichen Zetteln, Briefen und weiteren Texten fort als ein eigenes Prinzip von Evolution. N2 - The travel diaries of Humboldt’s journey to the Americas (1799-1804) form a corpus of research in the form of written entries, tables, diagrams and sketches and serve as a continuation of the Roman “paper museums” of the 17th century. They can be seen as microcosms of small Kunstkammern (cabinets of curiosity) in which specimens from nature, artworks and working materials are documented and presented together in a common space for reflection and contemplation. The focus of this paper is Humboldt’s conception of a “designed determination” through particularly memorable images and forms. His aesthetic of an overall vision of nature bears a striking similarity to Charles Darwin’s theory of natural beauty. His travel diaries reveal a heterogeneous character, imbued with a vibrancy that is attained through both the various formats of different notebooks, as well as by the inconsistent treatment of the of the booklet’s paper. In the form of countless notes, letters and further texts, this dynamic process establishes the framework for its own principal of evolution. N2 - I Reisetagebücher („diari di viaggio“) scrisse durante il suo viaggio in America del Sud (1799-1804) costituiscono un compendio di annotazioni scritte, tabelle, diagrammi e disegni, che appare legato alla tradizione dei musei cartacei romani del Settecento. Questi diari possono essere considerati delle Kunstkammern in miniatura, in cui oggetti della natura, opere d’arte e strumenti di lavoro formano uno spazio di riflessione comune. Al centro dell’attenzione del presente contributo è l’idea humboldtiana di una determinazione del paesaggio attraverso immagini particolarmente facili da ricordare. In modo sorprendente, la riflessione estetica di Humboldt sul panorama naturale si avvicina all’idea di bellezza della natura di Charles Darwin. I Reisetagebücher mostrano un carattere eterogeneo e vivo, che si manifesta sia nel diverso formato dei quaderni, sia attraverso il trattamento inconsistente della carta. Questa dinamicità continua poi nei numerosi foglietti, nelle lettere, e in altri testi di Humboldt, e costituisce il principio di evoluzione a loro proprio. KW - amerikanische Reisetagebücher KW - Kunstgeschichte KW - Bildwissenschaft KW - Landschaft KW - Charles Darwin Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-88963 SN - 1617-5239 SN - 2568-3543 VL - XVI IS - 31 SP - 26 EP - 42 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Götz, Carmen ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - Die (Un-)Ordnung des Schreibens. Der Index général und die Amerikanischen Reisetagebücher JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Die Amerikanischen Reisetagebücher wurden von Alexander von Humboldt während seines gesamten Lebens genutzt, dabei annotiert, auseinandergenommen und in Teilen an andere Forscher weitergegeben. In seinem letzten Lebensjahrzehnt ließ er diese in jene neun ledernen Bände einbinden, die heute in der Staatsbibliothek zu Berlin – Preußischer Kulturbesitz überliefert sind. Eine der Leitthesen der bisherigen Forschung lautete, dass dabei ihre ursprüngliche Ordnung verlorenging bzw. dass sie in großer Unordnung neu gebunden wurden. In dem Beitrag wird gezeigt, dass diese Leitthese nicht zutrifft. Vielmehr darf von einem weitgehenden Erhalt des ursprünglichen Zustands der Tagebuchbände ausgegangen werden, jenes Zustands, der in dem 1805 in Berlin angefertigten alphabetischen Register zu seinen Manuskripten (Index général) überliefert ist. Analysiert wurden neben dem Index selbst die Materialität der Bän- de, besonders Paginierungssprünge und Schnittkanten. Zudem wurde die bestehende Foliierung kritisch hinterfragt. N2 - The American Travel Journals were used by Alexander von Humboldt throughout his life, annotated, taken apart and passed on in parts to other researchers. In the last decade of his life he had them bound in those nine leather volumes that are now preserved in the Berlin State Library – Prussian Cultural Heritage. Previous research used to uphold the argument that the original order of Humboldt’s texts was lost in the process or that they were rebound in great disorder. The article shows that this argument is misleading. Rather, it can be assumed that the original state of the journal volumes has been largely preserved, based on the information that has survived in the alphabetical index to his manuscripts (Index général) made in Berlin in 1805. In addition to the Index itself, the materiality of the volumes was analyzed, especially pagination gaps and cut edges. Furthermore, the existing foliation was critically examined. N2 - Le Journal de voyage américain a été utilisé par Alexander de Humboldt tout au long de sa vie, annoté, démonté et transmis en partie à d’autres chercheurs. Au cours de la dernière décennie de sa vie, il l’a fait relier dans les neuf volumes en cuir, aujourd’hui conservés à la Staatsbibliothek zu Berlin – Preußischer Kulturbesitz. L’une des thèses principales de la recherche menée jusqu’à présent était que l’ordre d’origine avait été perdu ou qu’ils avaient été reliés dans un grand désordre. L’article montre que cette thèse n’est pas correcte. On peut au contraire partir du principe que les volumes du Journal ont conservé dans une large mesure leur état d’origine, celui qui a été transmis dans l’index alphabétique de ses manuscrits (Index général) établi à Berlin en 1805. En plus de l’index lui-même, l’analyse a porté sur la matérialité des volumes, en particulier sur les sauts de pagination et les bords de coupe. En outre, la foliotation a été examinée de manière critique. KW - Amerikanische Reisetagebücher KW - Index général KW - Paginierung KW - Vollständigkeit KW - Überlieferungszustand KW - Ordnung KW - Unordnung Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-617820 SN - 2568-3543 SN - 1617-5239 VL - XXIV IS - 47 SP - 57 EP - 80 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Rehse, Jessica T1 - Didaktische Potenziale digitaler Spielwelten BT - eine Einleitung JF - „Wir alle treffen Entscheidungen im Leben, aber letztendlich treffen unsere Entscheidungen uns.“ : didaktische Potenziale digitaler Spielwelten Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-485383 SN - 978-3-86956-489-0 SP - 11 EP - 60 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Schweigel, Ulrike A1 - Batsios, Petros A1 - Müller-Taubenberger, Annette A1 - Gräf, Ralph A1 - Grafe, Marianne T1 - Dictyostelium spastin is involved in nuclear envelope dynamics during semi-closed mitosis JF - Nucleus N2 - Dictyostelium amoebae perform a semi-closed mitosis, in which the nuclear envelope is fenestrated at the insertion sites of the mitotic centrosomes and around the central spindle during karyokinesis. During late telophase the centrosome relocates to the cytoplasmic side of the nucleus, the central spindle disassembles and the nuclear fenestrae become closed. Our data indicate that Dictyostelium spastin (DdSpastin) is a microtubule-binding and severing type I membrane protein that plays a role in this process. Its mitotic localization is in agreement with a requirement for the removal of microtubules that would hinder closure of the fenestrae. Furthermore, DdSpastin interacts with the HeH/ LEM-family protein Src1 in BioID analyses as well as the inner nuclear membrane protein Sun1, and shows subcellular co-localizations with Src1, Sun1, the ESCRT component CHMP7 and the IST1-like protein filactin, suggesting that the principal pathway of mitotic nuclear envelope remodeling is conserved between animals and Dictyostelium amoebae. KW - Spastin KW - LEM-domain KW - ESCRT KW - sun1 KW - dictyostelium KW - nuclear envelope KW - mitosis Y1 - 2022 U6 - https://doi.org/10.1080/19491034.2022.2047289 SN - 1949-1034 SN - 1949-1042 VL - 13 IS - 1 SP - 144 EP - 154 PB - Taylor & Francis Group CY - Philadelphia ER - TY - JOUR A1 - Koonce, Michael A1 - Tikhonenko, Irina A1 - Gräf, Ralph T1 - Dictyostelium cell fixation BT - two simple tricks JF - Methods and protocols N2 - We share two simple modifications to enhance the fixation and imaging of relatively small, motile, and rounded model cells. These include cell centrifugation and the addition of trace amounts of glutaraldehyde to existing fixation methods. Though they need to be carefully considered in each context, they have been useful to our studies of the spatial relationships of the microtubule cytoskeletal system. KW - Dictyostelium KW - cell fixation KW - microscopy KW - microtubule KW - cytoskeleton Y1 - 2020 U6 - https://doi.org/10.3390/mps3030047 SN - 2409-9279 VL - 3 IS - 3 PB - MDPI CY - Basel ER - TY - JOUR A1 - Baer, Ella A1 - Bosch, Jannis A1 - Wilbert, Jürgen T1 - Diagnostik internalisierender Probleme im Schulkontext – das Erleben von Kindern in emotional herausfordernden Schulsituationen JF - PSI-Potsdam: Ergebnisbericht zu den Aktivitäten im Rahmen der Qualitätsoffensive Lehrerbildung (2019-2023) (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 3) N2 - Kinder mit internalisierenden Problemen erleben täglich herausfordernde akademische sowie soziale Situationen im Schulkontext. Dabei ist entscheidend, dass Lehrkräfte in der Lage sind diese Kinder zu identifizieren, um pädagogisch adäquat handeln zu können. Aufgrund der nach innen gerichteten Symptome stellt das Erkennen internalisierender Probleme eine große Herausforderung dar. Zur Diagnostik werden vorwiegend standardisierte Fragebögen eingesetzt, welche den Schulkontext sowie spezifische Altersgruppen und die damit einhergehende Veränderlichkeit von Emotionswahrnehmungen der betroffenen Kinder nur unzureichend berücksichtigen. Dieser Beitrag präsentiert die Ergebnisse einer Interviewstudie und diskutiert den Einsatz von Interviews als Methode zur Identifikation emotional relevanter Situationen aus der Perspektive von Kindern. Die Ergebnisse sollen der Ableitung alters- und kontextspezifischer Items dienen, um die Diagnostik internalisierender Schwierigkeiten weiterzuentwickeln. N2 - Children with internalizing problems face challenging academic as well as social situations in the school context. It is crucial that teachers are able to identify these children to act adequately. Due to the inwardly directed symptoms, identifying such problems is a major challenge. Standardized questionnaires, which are predominantly used for diagnosis, do not sufficiently consider the school context as well as specific age groups and the associated variability of emotion perceptions of the affected children. This paper presents the results of an interview study and discusses the use of interviews as a method for identifying emotionally relevant situations from the perspective of children. The results will be used to derive age- and context-specific items to further develop the diagnosis of internalizing difficulties. KW - internalisierende Probleme KW - Diagnostik KW - emotionales Erleben KW - Interviewstudie KW - internalizing problems KW - diagnostics KW - emotional experience KW - interview study Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-616688 SN - 978-3-86956-568-2 SN - 2626-3556 SN - 2626-4722 IS - 3 SP - 131 EP - 141 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Park, Jaeheung A1 - Stolle, Claudia A1 - Yamazaki, Yosuke A1 - Rauberg, Jan A1 - Michaelis, Ingo A1 - Olsen, Nils T1 - Diagnosing low-/mid-latitude ionospheric currents using platform magnetometers BT - CryoSat-2 and GRACE-FO JF - Earth, planets and space N2 - Electric currents flowing in the terrestrial ionosphere have conventionally been diagnosed by low-earth-orbit (LEO) satellites equipped with science-grade magnetometers and long booms on magnetically clean satellites. In recent years, there are a variety of endeavors to incorporate platform magnetometers, which are initially designed for navigation purposes, to study ionospheric currents. Because of the suboptimal resolution and significant noise of the platform magnetometers, however, most of the studies were confined to high-latitude auroral regions, where magnetic field deflections from ionospheric currents easily exceed 100 nT. This study aims to demonstrate the possibility of diagnosing weak low-/mid-latitude ionospheric currents based on platform magnetometers. We use navigation magnetometer data from two satellites, CryoSat-2 and the Gravity Recovery and Climate Experiment Follow-On (GRACE-FO), both of which have been intensively calibrated based on housekeeping data and a high-precision geomagnetic field model. Analyses based on 8 years of CryoSat-2 data as well as similar to 1.5 years of GRACE-FO data reproduce well-known climatology of inter-hemispheric field-aligned currents (IHFACs), as reported by previous satellite missions dedicated to precise magnetic observations. Also, our results show that C-shaped structures appearing in noontime IHFAC distributions conform to the shape of the South Atlantic Anomaly. The F-region dynamo currents are only partially identified in the platform magnetometer data, possibly because the currents are weaker than IHFACs in general and depend significantly on altitude and solar activity. Still, this study evidences noontime F-region dynamo currents at the highest altitude (717 km) ever reported. We expect that further data accumulation from continuously operating missions may reveal the dynamo currents more clearly during the next solar maximum. KW - Platform magnetometers KW - CryoSat-2 KW - GRACE-FO KW - Inter-hemispheric KW - field-aligned currents KW - F-region dynamo currents Y1 - 2020 U6 - https://doi.org/10.1186/s40623-020-01274-3 SN - 1343-8832 SN - 1880-5981 VL - 72 IS - 1 PB - Springer CY - New York ER - TY - JOUR A1 - Wetzel, Maria A1 - Kempka, Thomas A1 - Kühn, Michael T1 - Diagenetic trends of synthetic reservoir sandstone properties assessed by digital rock physics JF - Minerals N2 - Quantifying interactions and dependencies among geometric, hydraulic and mechanical properties of reservoir sandstones is of particular importance for the exploration and utilisation of the geological subsurface and can be assessed by synthetic sandstones comprising the microstructural complexity of natural rocks. In the present study, three highly resolved samples of the Fontainebleau, Berea and Bentheim sandstones are generated by means of a process-based approach, which combines the gravity-driven deposition of irregularly shaped grains and their diagenetic cementation by three different schemes. The resulting evolution in porosity, permeability and rock stiffness is examined and compared to the respective micro-computer tomographic (micro-CT) scans. The grain contact-preferential scheme implies a progressive clogging of small throats and consequently produces considerably less connected and stiffer samples than the two other schemes. By contrast, uniform quartz overgrowth continuously alters the pore space and leads to the lowest elastic properties. The proposed stress-dependent cementation scheme combines both approaches of contact-cement and quartz overgrowth, resulting in granulometric, hydraulic and elastic properties equivalent to those of the respective micro-CT scans, where bulk moduli slightly deviate by 0.8%, 4.9% and 2.5% for the Fontainebleau, Berea and Bentheim sandstone, respectively. The synthetic samples can be further altered to examine the impact of mineral dissolution or precipitation as well as fracturing on various petrophysical correlations, which is of particular relevance for numerous aspects of a sustainable subsurface utilisation. KW - digital core reconstruction KW - micro-CT scan KW - pore-scale KW - cementation KW - permeability-porosity relationship KW - elastic rock properties KW - numerical KW - simulation Y1 - 2021 U6 - https://doi.org/10.3390/min11020151 SN - 2075-163X VL - 11 IS - 2 PB - MDPI CY - Basel ER - TY - JOUR A1 - Rausch, Ann-Kristin A1 - Brockmeyer, Robert A1 - Schwerdtle, Tanja T1 - Development, validation, and application of a multi-method for the determination of mycotoxins, plant growth regulators, tropane alkaloids, and pesticides in cereals by two-dimensional liquid chromatography tandem mass spectrometry JF - Analytical & bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry, Analusis and Quimica analitica N2 - Mycotoxins and pesticides regularly co-occur in agricultural products worldwide. Thus, humans can be exposed to both toxic contaminants and pesticides simultaneously, and multi-methods assessing the occurrence of various food contaminants and residues in a single method are necessary. A two-dimensional high performance liquid chromatography tandem mass spectrometry method for the analysis of 40 (modified) mycotoxins, two plant growth regulators, two tropane alkaloids, and 334 pesticides in cereals was developed. After an acetonitrile/water/formic acid (79:20:1, v/v/v) multi-analyte extraction procedure, extracts were injected into the two-dimensional setup, and an online clean-up was performed. The method was validated according to Commission Decision (EC) no. 657/2002 and document N° SANTE/12682/2019. Good linearity (R2 > 0.96), recovery data between 70-120%, repeatability and reproducibility values < 20%, and expanded measurement uncertainties < 50% were obtained for a wide range of analytes, including very polar substances like deoxynivalenol-3-glucoside and methamidophos. However, results for fumonisins, zearalenone-14,16-disulfate, acid-labile pesticides, and carbamates were unsatisfying. Limits of quantification meeting maximum (residue) limits were achieved for most analytes. Matrix effects varied highly (−85 to +1574%) and were mainly observed for analytes eluting in the first dimension and early-eluting analytes in the second dimension. The application of the method demonstrated the co-occurrence of different types of cereals with 28 toxins and pesticides. Overall, 86% of the samples showed positive findings with at least one mycotoxin, plant growth regulator, or pesticide. KW - 2D-LC-MS/MS KW - Multi-method KW - Mycotoxins KW - Modified mycotoxins KW - Pesticides KW - Cereals Y1 - 2021 U6 - https://doi.org/10.1007/s00216-021-03239-1 SN - 1618-2650 SN - 1618-2642 VL - 413 IS - 11 SP - 3041 EP - 3054 PB - Springer CY - Berlin ER - TY - JOUR A1 - Naliboff, John B. A1 - Glerum, Anne A1 - Brune, Sascha A1 - Péron-Pinvidic, G. A1 - Wrona, Thilo T1 - Development of 3-D rift heterogeneity through fault network evolution JF - Geophysical Research Letters N2 - Observations of rift and rifted margin architecture suggest that significant spatial and temporal structural heterogeneity develops during the multiphase evolution of continental rifting. Inheritance is often invoked to explain this heterogeneity, such as preexisting anisotropies in rock composition, rheology, and deformation. Here, we use high-resolution 3-D thermal-mechanical numerical models of continental extension to demonstrate that rift-parallel heterogeneity may develop solely through fault network evolution during the transition from distributed to localized deformation. In our models, the initial phase of distributed normal faulting is seeded through randomized initial strength perturbations in an otherwise laterally homogeneous lithosphere extending at a constant rate. Continued extension localizes deformation onto lithosphere-scale faults, which are laterally offset by tens of km and discontinuous along-strike. These results demonstrate that rift- and margin-parallel heterogeneity of large-scale fault patterns may in-part be a natural byproduct of fault network coalescence. KW - magma-poor KW - continental lithosphere KW - extension KW - insights KW - margins KW - architecture KW - systems KW - models KW - sea KW - reactivation Y1 - 2019 VL - 47 IS - 13 PB - John Wiley & Sons, Inc. CY - New Jersey ER - TY - JOUR A1 - Franzke, Jochen T1 - Deutschlands Krisenmanagement in der CORONA-Pandemie. BT - Herausforderungen eines föderalen politisch-administrativen Systems JF - Rocznik Integracji Europejskiej JF - Yearbook of European integration KW - CORONA-Krise KW - Deutschland KW - Föderalismus KW - Krisenmanagement KW - Öffentliche Verwaltung Y1 - 2020 U6 - https://doi.org/10.14746/rie.2020.14.21 SN - 1899-6256 VL - 14 SP - 325 EP - 342 PB - Uniwersytet im. Adama Mickiewicza w Poznaniu CY - Poznań ER - TY - JOUR A1 - Bishop, Christopher Allen A1 - Machate, Tina A1 - Henning, Thorsten A1 - Henkel-Oberländer, Janin A1 - Püschel, Gerhard A1 - Weber, Daniela A1 - Grune, Tilman A1 - Klaus, Susanne A1 - Weitkunat, Karolin T1 - Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle JF - Nutrition & Diabetes N2 - Objective: Current data regarding the roles of branched-chain amino acids (BCAA) in metabolic health are rather conflicting, as positive and negative effects have been attributed to their intake. Methods: To address this, individual effects of leucine and valine were elucidated in vivo (C57BL/6JRj mice) with a detailed phenotyping of these supplementations in high-fat (HF) diets and further characterization with in vitro approaches (C2C12 myocytes). Results: Here, we demonstrate that under HF conditions, leucine mediates beneficial effects on adiposity and insulin sensitivity, in part due to increasing energy expenditure-likely contributing partially to the beneficial effects of a higher milk protein intake. On the other hand, valine feeding leads to a worsening of HF-induced health impairments, specifically reducing glucose tolerance/ insulin sensitivity. These negative effects are driven by an accumulation of the valine-derived metabolite 3-hydroxyisobutyrate (3HIB). Higher plasma 3-HIB levels increase basal skeletal muscle glucose uptake which drives glucotoxicity and impairs myocyte insulin signaling. Conclusion: These data demonstrate the detrimental role of valine in an HF context and elucidate additional targetable pathways in the etiology of BCAA-induced obesity and insulin resistance. Y1 - 2022 U6 - https://doi.org/10.1038/s41387-022-00200-8 SN - 2044-4052 VL - 12 IS - 1 PB - Nature Publishing Group CY - London ER - TY - JOUR A1 - Agarwal, Saloni A1 - Hamidizadeh, Mojdeh A1 - Bier, Frank Fabian T1 - Detection of reverse transcriptase LAMP-amplified nucleic acid from oropharyngeal viral swab samples using biotinylated DNA probes through a lateral flow assay JF - Biosensors : open access journal N2 - This study focuses on three key aspects: (a) crude throat swab samples in a viral transport medium (VTM) as templates for RT-LAMP reactions; (b) a biotinylated DNA probe with enhanced specificity for LFA readouts; and (c) a digital semi-quantification of LFA readouts. Throat swab samples from SARS-CoV-2 positive and negative patients were used in their crude (no cleaning or pre-treatment) forms for the RT-LAMP reaction. The samples were heat-inactivated but not treated for any kind of nucleic acid extraction or purification. The RT-LAMP (20 min processing time) product was read out by an LFA approach using two labels: FITC and biotin. FITC was enzymatically incorporated into the RT-LAMP amplicon with the LF-LAMP primer, and biotin was introduced using biotinylated DNA probes, specifically for the amplicon region after RT-LAMP amplification. This assay setup with biotinylated DNA probe-based LFA readouts of the RT-LAMP amplicon was 98.11% sensitive and 96.15% specific. The LFA result was further analysed by a smartphone-based IVD device, wherein the T-line intensity was recorded. The LFA T-line intensity was then correlated with the qRT-PCR Ct value of the positive swab samples. A digital semi-quantification of RT-LAMP-LFA was reported with a correlation coefficient of R2 = 0.702. The overall RT-LAMP-LFA assay time was recorded to be 35 min with a LoD of three RNA copies/µL (Ct-33). With these three advancements, the nucleic acid testing-point of care technique (NAT-POCT) is exemplified as a versatile biosensor platform with great potential and applicability for the detection of pathogens without the need for sample storage, transportation, or pre-processing. KW - RT-LAMP KW - LFA KW - NAAT-LFA KW - semi-quantitative KW - surveillance-based diagnostics Y1 - 2023 U6 - https://doi.org/10.3390/bios13110988 SN - 2079-6374 VL - 13 IS - 11 PB - MDPI CY - Basel ER - TY - JOUR A1 - Rethfeldt, Nina A1 - Brinkmann, Pia A1 - Riebe, Daniel A1 - Beitz, Toralf A1 - Köllner, Nicole A1 - Altenberger, Uwe A1 - Löhmannsröben, Hans-Gerd T1 - Detection of Rare Earth Elements in Minerals and Soils by Laser-Induced Breakdown Spectroscopy (LIBS) Using Interval PLS JF - Minerals N2 - The numerous applications of rare earth elements (REE) has lead to a growing global demand and to the search for new REE deposits. One promising technique for exploration of these deposits is laser-induced breakdown spectroscopy (LIBS). Among a number of advantages of the technique is the possibility to perform on-site measurements without sample preparation. Since the exploration of a deposit is based on the analysis of various geological compartments of the surrounding area, REE-bearing rock and soil samples were analyzed in this work. The field samples are from three European REE deposits in Sweden and Norway. The focus is on the REE cerium, lanthanum, neodymium and yttrium. Two different approaches of data analysis were used for the evaluation. The first approach is univariate regression (UVR). While this approach was successful for the analysis of synthetic REE samples, the quantitative analysis of field samples from different sites was influenced by matrix effects. Principal component analysis (PCA) can be used to determine the origin of the samples from the three deposits. The second approach is based on multivariate regression methods, in particular interval PLS (iPLS) regression. In comparison to UVR, this method is better suited for the determination of REE contents in heterogeneous field samples. View Full-Text KW - LIBS KW - rare earth elements KW - minerals KW - PCA KW - iPLS regression Y1 - 2021 U6 - https://doi.org/10.3390/min11121379 SN - 2075-163X VL - 11 SP - 1 EP - 17 PB - MDPI CY - Basel, Schweiz ER - TY - JOUR A1 - Oesch, Tyler A1 - Weise, Frank A1 - Bruno, Giovanni T1 - Detection and quantification of cracking in concrete aggregate through virtual data fusion of X-ray computed tomography images JF - Materials N2 - In this work, which is part of a larger research program, a framework called "virtual data fusion" was developed to provide an automated and consistent crack detection method that allows for the cross-comparison of results from large quantities of X-ray computed tomography (CT) data. A partial implementation of this method in a custom program was developed for use in research focused on crack quantification in alkali-silica reaction (ASR)-sensitive concrete aggregates. During the CT image processing, a series of image analyses tailored for detecting specific, individual crack-like characteristics were completed. The results of these analyses were then "fused" in order to identify crack-like objects within the images with much higher accuracy than that yielded by any individual image analysis procedure. The results of this strategy demonstrated the success of the program in effectively identifying crack-like structures and quantifying characteristics, such as surface area and volume. The results demonstrated that the source of aggregate has a very significant impact on the amount of internal cracking, even when the mineralogical characteristics remain very similar. River gravels, for instance, were found to contain significantly higher levels of internal cracking than quarried stone aggregates of the same mineralogical type. KW - X-ray computed tomography (CT) KW - concrete KW - alkali-silica reaction (ASR) KW - ASR-sensitive aggregate KW - solubility test KW - specific surface area KW - crack KW - detection KW - automated image processing KW - damage quantification Y1 - 2020 U6 - https://doi.org/10.3390/ma13183921 SN - 1996-1944 VL - 13 IS - 18 PB - MDPI CY - Basel ER - TY - JOUR A1 - Lehr, Christian A1 - Dannowski, Ralf A1 - Kalettka, Thomas A1 - Merz, Christoph A1 - Schröder, Boris A1 - Steidl, Jörg A1 - Lischeid, Gunnar T1 - Detecting dominant changes in irregularly sampled multivariate water quality data sets JF - Hydrology and earth system sciences : HESS N2 - Time series of groundwater and stream water quality often exhibit substantial temporal and spatial variability, whereas typical existing monitoring data sets, e.g. from environmental agencies, are usually characterized by relatively low sampling frequency and irregular sampling in space and/or time. This complicates the differentiation between anthropogenic influence and natural variability as well as the detection of changes in water quality which indicate changes in single drivers. We suggest the new term "dominant changes" for changes in multivariate water quality data which concern (1) multiple variables, (2) multiple sites and (3) long-term patterns and present an exploratory framework for the detection of such dominant changes in data sets with irregular sampling in space and time. Firstly, a non-linear dimension-reduction technique was used to summarize the dominant spatiotemporal dynamics in the multivariate water quality data set in a few components. Those were used to derive hypotheses on the dominant drivers influencing water quality. Secondly, different sampling sites were compared with respect to median component values. Thirdly, time series of the components at single sites were analysed for long-term patterns. We tested the approach with a joint stream water and groundwater data set quality consisting of 1572 samples, each comprising sixteen variables, sampled with a spatially and temporally irregular sampling scheme at 29 sites in northeast Germany from 1998 to 2009. The first four components were interpreted as (1) an agriculturally induced enhancement of the natural background level of solute concentration, (2) a redox sequence from reducing conditions in deep groundwater to post-oxic conditions in shallow groundwater and oxic conditions in stream water, (3) a mixing ratio of deep and shallow groundwater to the streamflow and (4) sporadic events of slurry application in the agricultural practice. Dominant changes were observed for the first two components. The changing intensity of the first component was interpreted as response to the temporal variability of the thickness of the unsaturated zone. A steady increase in the second component at most stream water sites pointed towards progressing depletion of the denitrification capacity of the deep aquifer. Y1 - 2018 U6 - https://doi.org/10.5194/hess-22-4401-2018 SN - 1027-5606 SN - 1607-7938 VL - 22 IS - 8 SP - 4401 EP - 4424 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Studemund-Halévy, Michael T1 - Desperados at Sea JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. JF - PaRDeS : Journal of the Association for Jewish Studies in Germany N2 - Pirates are fortune-seeking fighters at sea. Their exploits fire the imaginations of their victims and admirers, drawing a veil over individuals who rarely bear a real name and pursue their adventurous occupations as buccaneers, filibusters, freebooters, privateers, pirates, or corsairs. Piracy, corsairing, and contraband trade were epidemic among the Egyptians and the Phoenicians, the Greeks and the Vikings, the Spaniards and the Ottomans, the Muslims, and the Christians. And the Jews. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-585796 SN - 978-3-86956-552-1 SN - 1614-6492 SN - 1862-7684 IS - 28 SP - 100 EP - 115 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Lau, Skadi A1 - Gossen, Manfred A1 - Lendlein, Andreas T1 - Designing cardiovascular implants taking in view the endothelial basement membrane JF - International journal of molecular sciences N2 - Insufficient endothelialization of cardiovascular grafts is a major hurdle in vascular surgery and regenerative medicine, bearing a risk for early graft thrombosis. Neither of the numerous strategies pursued to solve these problems were conclusive. Endothelialization is regulated by the endothelial basement membrane (EBM), a highly specialized part of the vascular extracellular matrix. Thus, a detailed understanding of the structure-function interrelations of the EBM components is fundamental for designing biomimetic materials aiming to mimic EBM functions. In this review, a detailed description of the structure and functions of the EBM are provided, including the luminal and abluminal interactions with adjacent cell types, such as vascular smooth muscle cells. Moreover, in vivo as well as in vitro strategies to build or renew EBM are summarized and critically discussed. The spectrum of methods includes vessel decellularization and implant biofunctionalization strategies as well as tissue engineering-based approaches and bioprinting. Finally, the limitations of these methods are highlighted, and future directions are suggested to help improve future design strategies for EBM-inspired materials in the cardiovascular field. KW - endothelial cells KW - bioinstructive implants KW - vascular grafts KW - tissue KW - engineering KW - bioprinting KW - bioinspired materials KW - biological membrane KW - endothelial basement membrane KW - biomaterial Y1 - 2021 U6 - https://doi.org/10.3390/ijms222313120 SN - 1422-0067 VL - 22 IS - 23 PB - MDPI CY - Basel ER - TY - JOUR A1 - Dragičević, Nikolina A1 - Vladova, Gergana A1 - Ullrich, André T1 - Design thinking capabilities in the digital world BT - A bibliometric analysis of emerging trends JF - Frontiers in Education N2 - Recent research suggests that design thinking practices may foster the development of needed capabilities in new digitalised landscapes. However, existing publications represent individual contributions, and we lack a holistic understanding of the value of design thinking in a digital world. No review, to date, has offered a holistic retrospection of this research. In response, in this bibliometric review, we aim to shed light on the intellectual structure of multidisciplinary design thinking literature related to capabilities relevant to the digital world in higher education and business settings, highlight current trends and suggest further studies to advance theoretical and empirical underpinnings. Our study addresses this aim using bibliometric methods—bibliographic coupling and co-word analysis as they are particularly suitable for identifying current trends and future research priorities at the forefront of the research. Overall, bibliometric analyses of the publications dealing with the related topics published in the last 10 years (extracted from the Web of Science database) expose six trends and two possible future research developments highlighting the expanding scope of the design thinking scientific field related to capabilities required for the (more sustainable and human-centric) digital world. Relatedly, design thinking becomes a relevant approach to be included in higher education curricula and human resources training to prepare students and workers for the changing work demands. This paper is well-suited for education and business practitioners seeking to embed design thinking capabilities in their curricula and for design thinking and other scholars wanting to understand the field and possible directions for future research. KW - design thinking KW - digital technologies KW - digital transformation KW - capabilities KW - skills Y1 - 2023 U6 - https://doi.org/10.3389/feduc.2022.1012478 SN - 2504-284X VL - 7 PB - Frontiers CY - Lausanne, Schweiz ER - TY - JOUR A1 - Sagu Tchewonpi, Sorel A1 - Huschek, Gerd A1 - Waldbach Braga, Tess A1 - Rackiewicz, Michal A1 - Homann, Thomas A1 - Rawel, Harshadrai Manilal T1 - Design of Experiment (DoE) for Optimization of HPLC Conditions for the Simultaneous Fractionation of Seven α-Amylase/Trypsin Inhibitors from Wheat (Triticum aestivum L.) JF - Processes : open access journal N2 - Wheat alpha-amylase/trypsin inhibitors remain a subject of interest considering the latest findings showing their implication in wheat-related non-celiac sensitivity (NCWS). Understanding their functions in such a disorder is still unclear and for further study, the need for pure ATI molecules is one of the limiting problems. In this work, a simplified approach based on the successive fractionation of ATI extracts by reverse phase and ion exchange chromatography was developed. ATIs were first extracted from wheat flour using a combination of Tris buffer and chloroform/methanol methods. The separation of the extracts on a C18 column generated two main fractions of interest F1 and F2. The response surface methodology with the Doehlert design allowed optimizing the operating parameters of the strong anion exchange chromatography. Finally, the seven major wheat ATIs namely P01083, P17314, P16850, P01085, P16851, P16159, and P83207 were recovered with purity levels (according to the targeted LC-MS/MS analysis) of 98.2 ± 0.7; 98.1 ± 0.8; 97.9 ± 0.5; 95.1 ± 0.8; 98.3 ± 0.4; 96.9 ± 0.5, and 96.2 ± 0.4%, respectively. MALDI-TOF-MS analysis revealed single peaks in each of the pure fractions and the mass analysis yielded deviations of 0.4, 1.9, 0.1, 0.2, 0.2, 0.9, and 0.1% between the theoretical and the determined masses of P01083, P17314, P16850, P01085, P16851, P16159, and P83207, respectively. Overall, the study allowed establishing an efficient purification process of the most important wheat ATIs. This paves the way for further in-depth investigation of the ATIs to gain more knowledge related to their involvement in NCWS disease and to allow the absolute quantification in wheat samples. KW - wheat KW - α-amylase/trypsin inhibitors KW - fractionation KW - purification KW - reversed-phase chromatography KW - ion-exchange chromatography KW - design of experiment KW - LC–MS/MS KW - MALDI-TOF-MS Y1 - 2022 U6 - https://doi.org/10.3390/pr10020259 SN - 2227-9717 VL - 10 SP - 1 EP - 18 PB - MDPI CY - Basel, Schweiz ET - 2 ER - TY - JOUR A1 - Grum, Marcus A1 - Hiessl, Werner A1 - Maresch, Karl A1 - Gronau, Norbert T1 - Design of a neuronal training modeling language BT - exemplified with the AI-based dynamic GUI adaption JF - AIS-Transactions on enterprise systems N2 - As the complexity of learning task requirements, computer infrastruc- tures and knowledge acquisition for artificial neuronal networks (ANN) is in- creasing, it is challenging to talk about ANN without creating misunderstandings. An efficient, transparent and failure-free design of learning tasks by models is not supported by any tool at all. For this purpose, particular the consideration of data, information and knowledge on the base of an integration with knowledge- intensive business process models and a process-oriented knowledge manage- ment are attractive. With the aim of making the design of learning tasks express- ible by models, this paper proposes a graphical modeling language called Neu- ronal Training Modeling Language (NTML), which allows the repetitive use of learning designs. An example ANN project of AI-based dynamic GUI adaptation exemplifies its use as a first demonstration. KW - AI and business informatics KW - development of AI-based systems KW - AI-based decision support system KW - cooperative AI (human-in-the-loop) KW - process-oriented knowledge acquisition KW - modeling language Y1 - 2021 UR - https://www.aes-journal.com/index.php/ais-tes/article/view/20/18 U6 - https://doi.org/10.30844/aistes.v5i1.20 SN - 1867-7134 VL - 5 IS - 1 PB - GITO-Publ., Verl. für Industrielle Informationstechnik und Organisation CY - Berlin ER - TY - JOUR A1 - Genderjahn, Steffi A1 - Alawi, Mashal A1 - Mangelsdorf, Kai A1 - Horn, Fabian A1 - Wagner, Dirk T1 - Desiccation- and saline-solerant bacteria and archaea in kalahari an sediments JF - Frontiers in microbiology N2 - More than 41% of the Earth’s land area is covered by permanent or seasonally arid dryland ecosystems. Global development and human activity have led to an increase in aridity, resulting in ecosystem degradation and desertification around the world. The objective of the present work was to investigate and compare the microbial community structure and geochemical characteristics of two geographically distinct saline pan sediments in the Kalahari Desert of southern Africa. Our data suggest that these microbial communities have been shaped by geochemical drivers, including water content, salinity, and the supply of organic matter. Using Illumina 16S rRNA gene sequencing, this study provides new insights into the diversity of bacteria and archaea in semi-arid, saline, and low-carbon environments. Many of the observed taxa are halophilic and adapted to water-limiting conditions. The analysis reveals a high relative abundance of halophilic archaea (primarily Halobacteria), and the bacterial diversity is marked by an abundance of Gemmatimonadetes and spore-forming Firmicutes. In the deeper, anoxic layers, candidate division MSBL1, and acetogenic bacteria (Acetothermia) are abundant. Together, the taxonomic information and geochemical data suggest that acetogenesis could be a prevalent form of metabolism in the deep layers of a saline pan. KW - saline pan KW - Kalahari KW - Halobacteria KW - Gemmatimonadetes KW - Firmicutes Y1 - 2018 U6 - https://doi.org/10.3389/fmicb.2018.02082 SN - 1664-302X VL - 9 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Giannatelli, Ada A1 - Tomasini, Alessandra ED - Meinel, Christoph ED - Schweiger, Stefanie ED - Staubitz, Thomas ED - Conrad, Robert ED - Alario Hoyos, Carlos ED - Ebner, Martin ED - Sancassani, Susanna ED - Żur, Agnieszka ED - Friedl, Christian ED - Halawa, Sherif ED - Gamage, Dilrukshi ED - Scott, Jeffrey ED - Kristine Jonson Carlon, May ED - Deville, Yves ED - Gaebel, Michael ED - Delgado Kloos, Carlos ED - von Schmieden, Karen T1 - Descriptors and EU Standards to support the recognition of MOOCs JF - EMOOCs 2023 : Post-Covid Prospects for Massive Open Online Courses - Boost or Backlash? N2 - Digital technologies have enabled a variety of learning offers that opened new challenges in terms of recognition of formal, informal and non-formal learning, such as MOOCs. This paper focuses on how providing relevant data to describe a MOOC is conducive to increase the transparency of information and, ultimately, the flexibility of European higher education. The EU-funded project ECCOE took up these challenges and developed a solution by identifying the most relevant descriptors of a learning opportunity with a view to supporting a European system for micro-credentials. Descriptors indicate the specific properties of a learning opportunity according to European standards. They can provide a recognition framework also for small volumes of learning (micro-credentials) to support the integration of non-formal learning (MOOCs) into formal learning (e.g. institutional university courses) and to tackle skills shortage, upskilling and reskilling by acquiring relevant competencies. The focus on learning outcomes can facilitate the recognition of skills and competences of students and enhance both virtual and physical mobility and employability. This paper presents two contexts where ECCOE descriptors have been adopted: the Politecnico di Milano MOOC platform (Polimi Open Knowledge – POK), which is using these descriptors as the standard information to document the features of its learning opportunities, and the EU-funded Uforest project on urban forestry, which developed a blended training program for students of partner universities whose MOOCs used the ECCOE descriptors. Practice with ECCOE descriptors shows how they can be used not only to detail MOOC features, but also as a compass to design the learning offer. In addition, some rules of thumb can be derived and applied when using specific descriptors. KW - Digitale Bildung KW - Kursdesign KW - MOOC KW - Micro Degree KW - Online-Lehre KW - Onlinekurs KW - Onlinekurs-Produktion KW - digital education KW - e-learning KW - micro degree KW - micro-credential KW - online course creation KW - online course design KW - online teaching Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-623967 SP - 133 EP - 146 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Rancan, Fiorenza A1 - Volkmann, Hildburg A1 - Giulbudagian, Michael A1 - Schumacher, Fabian A1 - Stanko, Jessica Isolde A1 - Kleuser, Burkhard A1 - Blume-Peytavi, Ulrike A1 - Calderon, Marcelo A1 - Vogt, Annika T1 - Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels JF - Pharmaceutics : Molecular Diversity Preservation International N2 - Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin. In this study, we compared the skin penetration of tacrolimus formulated in tNGs with a commercial 0.1% tacrolimus ointment. The penetration of the drug was investigated in ex vivo abdominal and breast skin, while different methods for skin barrier disruption were investigated to improve skin permeability or simulate inflammatory conditions with compromised skin barrier. The amount of penetrated tacrolimus was measured in skin extracts by liquid chromatography tandem-mass spectrometry (LC-MS/MS), whereas the inflammatory markers IL-6 and IL-8 were detected by enzyme-linked immunosorbent assay (ELISA). Higher amounts of tacrolimus penetrated in breast as compared to abdominal skin or in barrier-disrupted as compared to intact skin, confirming that the stratum corneum is the main barrier for tacrolimus skin penetration. The anti-proliferative effect of the penetrated drug was measured in skin tissue/Jurkat cells co-cultures. Interestingly, tNGs exhibited similar anti-proliferative effects as the 0.1% tacrolimus ointment. We conclude that polyglycerol-based nanogels represent an interesting alternative to paraffin-based formulations for the treatment of inflammatory skin conditions. KW - tacrolimus formulation KW - nanogels KW - skin penetration KW - drug delivery KW - human excised skin KW - Jurkat cells Y1 - 2019 U6 - https://doi.org/10.3390/pharmaceutics11080394 SN - 1999-4923 VL - 11 IS - 8 PB - MDPI CY - Basel ER - TY - JOUR A1 - Falkenhagen, Undine A1 - Knöchel, Jane A1 - Kloft, Charlotte A1 - Huisinga, Wilhelm T1 - Deriving mechanism-based pharmacodynamic models by reducing quantitative systems pharmacology models BT - an application to warfarin JF - CPT: Pharmacometrics & Systems Pharmacology N2 - Quantitative systems pharmacology (QSP) models integrate comprehensive qualitative and quantitative knowledge about pharmacologically relevant processes. We previously proposed a first approach to leverage the knowledge in QSP models to derive simpler, mechanism-based pharmacodynamic (PD) models. Their complexity, however, is typically still too large to be used in the population analysis of clinical data. Here, we extend the approach beyond state reduction to also include the simplification of reaction rates, elimination of reactions, and analytic solutions. We additionally ensure that the reduced model maintains a prespecified approximation quality not only for a reference individual but also for a diverse virtual population. We illustrate the extended approach for the warfarin effect on blood coagulation. Using the model-reduction approach, we derive a novel small-scale warfarin/international normalized ratio model and demonstrate its suitability for biomarker identification. Due to the systematic nature of the approach in comparison with empirical model building, the proposed model-reduction algorithm provides an improved rationale to build PD models also from QSP models in other applications. Y1 - 2023 U6 - https://doi.org/10.1002/psp4.12903 SN - 2163-8306 VL - 12 IS - 4 SP - 432 EP - 443 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Ciaccio, Laura Anna A1 - Burchert, Frank A1 - Semenza, Carlo T1 - Derivational morphology in agrammatic aphasia BT - a comparison between prefixed and suffixed words JF - Frontiers in Psychology N2 - Although a relatively large number of studies on acquired language impairments have tested the case of derivational morphology, none of these have specifically investigated whether there are differences in how prefixed and suffixed derived words are impaired. Based on linguistic and psycholinguistic considerations on prefixed and suffixed derived words, differences in how these two types of derivations are processed, and consequently impaired, are predicted. In the present study, we investigated the errors produced in reading aloud simple, prefixed, and suffixed words by three German individuals with agrammatic aphasia (NN, LG, SA). We found that, while NN and LG produced similar numbers of errors with prefixed and suffixed words, SA showed a selective impairment for prefixed words. Furthermore, NN and SA produced more errors specifically involving the affix with prefixed words than with suffixed words. We discuss our findings in terms of relative position of stem and affix in prefixed and suffixed words, as well as in terms of specific properties of prefixes and suffixes. KW - Broca’s aphasia KW - morphological decomposition KW - morphological errors KW - derivation KW - prefixes Y1 - 2019 U6 - https://doi.org/10.3389/fpsyg.2020.01070 SN - 1664-1078 VL - 11 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Meier, Jana A1 - Küth, Simon A1 - Scholl, Daniel A1 - Vogelsang, Christoph A1 - Watson, Christina ED - Mientus, Lukas ED - Klempin, Christiane ED - Nowak, Anna T1 - Der Zyklus von Planung und Reflexion BT - Zusammenhänge zwischen der generischen Unterrichtsplanungsfähigkeit und der Reflexionskompetenz angehender Lehrkräfte JF - Reflexion in der Lehrkräftebildung: Empirisch – Phasenübergreifend – Interdisziplinär (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 4) N2 - Auf der Zeitachse von Zyklusmodellen des Unterrichts wird der Handlungsreflexion eine zentrale Bedeutung zugesprochen: Vor seiner Umsetzung im Unterricht soll das kommende Handeln zunächst in einer antizipierenden Reflexion gedanklich entworfen werden, um seine Erfolgswahrscheinlichkeit zu erhöhen. Nach dem Unterricht soll es einer retrospektiven Reflexion unterzogen werden, in der die Handlungsumsetzung vor dem Hintergrund der Handlungsplanung evaluiert wird und Konsequenzen für künftige Handlungsplanungen gezogen werden. Trotz der Plausibilität dieses postulierten Zusammenhangs von antizipierender und retrospektiver Reflexion steht seine genauere empirische Untersuchung allerdings noch aus. In einer querschnittlichen Onlineerhebung werden diese beiden Reflexionsformen deshalb als generische Unterrichtsplanungsfähigkeit und Reflexionskompetenz spezifiziert, um ihren Zusammenhang mit Hilfe einer Stichprobe von angehenden Lehrkräften (N = 479) aus zwei Universitäten zu explorieren. Die gefundenen schwachen Zusammenhänge werden vor dem Hintergrund der Operationalisierungen und der Testmotivation der Teilnehmenden diskutiert. KW - Lehramtsstudierende KW - Reflexionskompetenz KW - Unterrichtsplanungsfähigkeit KW - Vignetten KW - Zyklusmodell Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-631422 SN - 978-3-86956-566-8 SN - 2626-3556 SN - 2626-4722 IS - 4 SP - 233 EP - 239 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Stottmeister, Ulrich ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - Der Mineraloge August Schmidt und die Entdeckung der Ural-Diamanten 1829 BT - Teil II: Schmidts wissenschaftlicher Diamanten-Beweis und sein weiteres Schicksal im Ural JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Aus Archivfunden und historischen Zeitungsberichten rekonstruiert der Artikel die Lebensspuren von August Schmidt (1802–1832) während seiner Tätigkeit im Ural als Mineraloge und Bergwerksverwalter. Ausführlich werden die von Schmidt angewendeten naturwissenschaftlichen Analysemethoden beschrieben, mit denen ihm der eindeutige Nachweis der ersten gefundenen Ural-Diamanten gelang. Schmidt überbrachte Alexander von Humboldt (1769–1859) einen der Diamanten als Geschenk seines Vorgesetzten, Adolphe Graf von Polier (1795–1830), und erhielt die Gelegenheit, Humboldt seine eigenen Ideen zur technischen Modernisierung und zur Energieeinsparung vorzustellen. Der frühe Tod von August Schmidt, der im Ural Fjodor Fjodorowitsch Schmidt genannt wurde, verhinderte weitgehend die Verwirklichung dieser Ideen und führte durch die Vornamensunterschiede zu gerichtlichen Auseinandersetzungen um seinen Nachlass. N2 - August Schmidt (1802–1832) during his time in the Urals as a mineralogist and mining administrator. The scientific analysis methods used by Schmidt with which he was able to clearly identify the first Ural diamonds found are described in detail. Schmidt presented Alexander von Humboldt (1769–1859) one of the diamonds as a gift from his superior, Adolphe Comte de Polier (1795–1830), and was given the opportunity to present Humboldt his own ideas for technical modernization and energy economy. The early death of August Schmidt, who was called Fyodor Fyodorovich Schmidt in the Urals, largely prevented the realization of these ideas and led to legal disputes over his estate due to the difference in first names. N2 - В статье на основе архивных материалов и исторических газетных сообщений реконструируется жизнь Августа Шмидта (1802–1832 гг.) во время его работы на Урале в качестве минералога и Управляющего рудником. Подробно описаны методы научного анализа, использованные Шмидтом, с помощью которых он смог однозначно идентифицировать первые найденные уральские алмазы. Шмидт передал Александру фон Гумбольдту (1769–1859) один из алмазов в качестве подарка от своего начальника, графа Адольфа Польера (1795–1830), и получил возможность представить Гумбольдту свои собственные идеи по технической модернизации и энергосбережению. Ранняя смерть Августа Шмидта, которого на Урале называли Фёдором Фёдоровичем Шмидтом, во многом помешала реализации этих идей и привела к судебным спорам по делам его наследствa из-за разного написания имени. KW - Diamanten-Identifikation KW - Gespräch mit Humboldt KW - August Schmidt KW - Mineralogie Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-589945 SN - 1617-5239 SN - 2568-3543 VL - XXIII IS - 44 SP - 131 EP - 160 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Reich, Karin ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - Der Humboldt’sche Magnetische Verein im historischen Kontext JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Der Humboldtsche Magnetische Verein (1829–1834) mit seinem Zentrum in Berlin, an dem 4 weitere Stationen mitwirkten, hatte einen Vorläufer, die Societas meteorologica Palatina (1780–1795). Diese verfügte über 17 über die Nordhalbkugel verteilte Stationen, an denen magnetische Beobachtungen durchgeführt wurden. Der Nachfolgeverein mit 61 über den Globus verteilten Stationen war der Göttinger Magnetische Verein (1834–1841). Der Humboldtsche Magnetische Verein war der erste, an dem die Gleichzeitigkeit der Beobachtungen, sog. korrespondierende Beobachtungen, anhand Berliner Zeit eingeführt wurden. Diese Methode wurde in Göttingen, wo Gauß und Weber seit 1834 über ein Magnetisches Observatorium verfügten, übernommen, modifiziert und verbessert, alle 61 angeschlossenen Stationen beobachteten gemäß Göttinger mittlerer Zeit. N2 - The Humboldtian Magnetic Association (1829–1834) with its center in Berlin had 4 further stations which contributed special data. Its predecessor, the Societas meteorologica Palatina (1780–1795), enclosed 17 stations distributed over the northern hemisphere, where magnetical observations took place. The Association which succeeded was the Göttinger magnetic Association (1834–1841); 61 stations collaborated with this Association. The Humboldtian Magnetic Association was the first, where contemporaneity was crucial, the so-called corresponding observations. Gauss and Weber in Göttingen, who were provided with a magnetical observatory since 1834, adopted this method and improved it, all their 61 stations observed according to Göttingen mean time. N2 - L’Association Magnétique de Humboldt (1829–1834) dont le centre était à Berlin avait 4 stations qui collaboraient. Elle avait un prédécesseur, à savoir la Societas meteorologica Palatina (1780–1795) qui disposait de 17 stations distribuées sur l’hémisphère du nord où des observations magnétiques étaient effectuées. Le successeur était l’Association Magnétique de Göttingen (1834–1841) qui disposait de 61 stations distribuées sur le globe. L’Association Magnétique de Humboldt était la première dans laquelle la simultanéité des observations, qui s’appelaient des observations correspondantes, a été introduite en s’appuyant sur le temps de Berlin. Gauss et Weber qui disposaient d’un observatoire magnétique depuis 1834 ont adopté, modifi é et amélioré cette méthode. Toutes leurs 61 stations observaient conformément au temps moyen de Göttingen. KW - Societas meteorologica Palatina KW - Humboldtscher Magnetischer Verein KW - Göttinger Magnetischer Verein KW - Gauß: Allgemeine Theorie des Erdmagnetismus Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-599818 SN - 2568-3543 SN - 1617-5239 VL - XXIV IS - 46 SP - 53 EP - 74 ER - TY - JOUR A1 - Schierl, Petra ED - Ambühl, Annemarie T1 - Der Heldenkörper in Szene gesetzt BT - die Muskeln des Hercules in Epos und Elegie JF - thersites 11: tessellae – Birthday Issue for Christine Walde N2 - Taking its cue from the portrayal of Hercules as muscleman in both films and ancient sculpture this article turns to poetry as a verbal art and examines when and how the hero's body comes into focus in Roman epic and elegy. It is argued that moments of crisis contrasting Hercules’ state in a given situation to his former heroic achievements give rise to representations of his body, while epic fight scenes rather draw attention to the bodies of his inferior opponents. The body is described through references to different body parts, qualified by attributes as masculine in elegiac contexts. A somewhat exotic word as tori suffices to highlight the hero’s muscular body. KW - Hercules KW - Roman epic KW - love elegy KW - body KW - heroism KW - masculinity Y1 - 2020 U6 - https://doi.org/10.34679/thersites.vol11.182 SN - 2364-7612 VL - 2020 IS - 11 SP - 31 EP - 68 ER - TY - JOUR A1 - Neumann, Sandra A1 - Zauke, Svenja T1 - Der FOCUS©-34-G als Fragebogen zur Einschätzung der kommunikativen Partizipation bei Kindern mit sprachlich-kommunikativem Unterstützungsbedarf unter sechs Jahren JF - Spektrum Patholinguistik 16 N2 - Der vorliegende Beitrag stellt die deutsche kurze Version des kommunikativen Partizipationsassessments ‚Fokus auf den Erfolg der Kommunikation für Kinder unter 6 Jahren (FOCUS©-34-G)‘ (Thomas-Stonell et al., 2012a) vor. Es werden die Entwicklung und psychometrische Validierung, Zielsetzung, Durchführung und Auswertung für den konkreten Einsatz in der sprachtherapeutischen Praxis beschrieben. KW - Kommunikative Partizipation KW - ICF-CY KW - Fragebogen KW - Sorgeberechtigte KW - Vorschulalter Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-613441 SN - 978-3-86956-559-0 SN - 1866-9433 SN - 1869-3822 IS - 16 SP - 83 EP - 94 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Reich, Karin A1 - Roussanova, Elena T1 - Der Briefwechsel zwischen Karl Kreil und Alexander von Humboldt, ein wichtiger Beitrag zur Geschichte des Erdmagnetismus JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - The correspondence between Alexander von Humboldt und Karl Kreil was voluminous, it concerned earth magnetism. But only one letter has survived. This letter was written by Kreil on September 3, 1836; one day later Kreil wrote a letter to Carl Friedrich Gauss with nearly the same contents, some sentences are even literally corresponding. Four letters from Kreil to Humboldt were published in the „Annalen der Physik und Chemie“. Some letters were mentioned in the biographical literature dealing with Kreil. These letters show, that the correspondence covered at least the period until 1851 and give information about the intensive relationship between the two scientists. A further interesting source is the library of Humboldt which unfortunately has not survived. The catalogue mentions nine works of Kreil some of them where annotated by Humboldt. This makes it plausible that the contacts even lasted until 1856. N2 - Die Korrespondenz zwischen Alexander von Humboldt und Karl Kreil war umfangreich und betraf den Erdmagnetismus. Aber heute ist nur noch ein einziger Brief im Original bekannt. Dieser Brief, den Kreil am 3. September 1836 Alexander von Humboldt zukommen ließ, stimmt inhaltlich und teilweise wortwörtlich mit dem Brief überein, den Kreil nur einen Tag später, am 4. September 1836, an Carl Friedrich Gauß schickte. Vier Briefe von Kreil an Humboldt wurden in den „Annalen der Physik und Chemie“ publiziert, eine nicht allzu große Anzahl weiterer Briefe an Humboldt wurde in der biographischen Literatur über Kreil und in Briefen Kreils an Koller und Gauß erwähnt. Aber nicht nur die lückenhafte und bruchstückhaft bekannte Korrespondenz zwischen Humboldt und Kreil, die bis 1851 reicht, gibt Aufschluss über die Beziehungen, sondern von besonderer Bedeutung ist des Weiteren der Bestand an Kreiliana in der Bibliothek Humboldts. Es handelt sich um neun Werke Kreils, das letzte aus dem Jahr 1856. Nachweisbare Kontakte zwischen Kreil und Humboldt fanden also mit Sicherheit mindestens bis zu diesem Jahr statt! N2 - La correspondance entre Alexander von Humboldt et Karl Kreil était volumineuse et concernait le magnétisme terrestre. Mais aujourd’hui, une seule lettre originale est encore connue. Kreil a envoyé cette lettre à Humboldt le 3 septembre 1836. C’est partiellement la même lettre – même les phrases coincident parfois – que Kreil a écrite à Carl Friedrich Gauss un jour plus tard. Quatre lettres de Kreil à Humboldt ont été publiées dans les „Annalen der Physik und Chemie“. Quelques lettres sont mentionnées dans la litérature biographique concernant Kreil. Les lettres démontrent que la correspondance peut être attribuée au moins à la période jusque 1851 et révèlent la relation intensive entre les deux savants. La bibliothèque de Humboldt qui malheureusement n’existe plus est une autre source intéressante. Le catalogue mentionne neuf oeuvres de Kreil dont quelques sont annotées par Humboldt. Donc, les contacts existaient vraisemblablement au moins jusque 1856. KW - Humboldt, Alexander von KW - Kreil, Karl KW - Gauß, Carl Friedrich KW - wissenschaftliche Korrespondenz KW - magnetische Beobachtungen in Mailand KW - Prag und Wien KW - Magnetometer von Carl Friedrich Gauß KW - Einfluss des Mondes und der Alpen auf erdmagnetische Kraft Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-98904 SN - 1617-5239 SN - 2568-3543 VL - XVII IS - 33 SP - 52 EP - 73 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Knobloch, Eberhard T1 - Der Briefwechsel zwischen Alexander von Humboldt und Charles Lyell BT - ein Überblick JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Der kurze Aufsatz gibt einen Überblick über den erhaltenen Briefwechsel zwischen A. v. Humboldt und Charles Lyell. Er veröffentlicht darüber hinaus einen undatierten, bisher unbekannten Brief Humboldts an Lyell. Der Brief kann mit Hilfe eines Briefes an Pertz datiert werden. Deshalb wird auch dieser Brief zum ersten Mal vollständig veröffentlicht. N2 - Le court article donne une vue d’ensemble de la correspondance conservée entre A. v. Humboldt et Charles Lyell. En plus, il publie une lettre sans date et inconnue jusqu’aujourd’hui de Humboldt à Lyell qui peut être datée au moyen d’une lettre à Pertz. Pour cette raison, cette lettre est aussi publiée complètement pour la première fois. N2 - The short paper gives a survey of the preserved correspondence between A. v. Humboldt and Charles Lyell. Moreover it publishes an undated, hitherto unknown letter of Humboldt to Lyell that can be dated by means of a letter to Pertz. For that reason this letter is also completely published for the first time. KW - Archiv KW - Briefe KW - Briefedition und -korrespondenz KW - Briefwechsel KW - Charles Lyell KW - von Humboldts Hand Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-84027 SN - 1617-5239 SN - 2568-3543 VL - XV IS - 28 SP - 7 EP - 13 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Marco Figuera, Ramiro A1 - Riedel, Christian A1 - Rossi, Angelo Pio A1 - Unnithan, Vikram T1 - Depth to diameter analysis on small simple craters at the lunar south pole - possible implications for ice harboring JF - Remote sensing N2 - In this paper, we present a study comparing the depth to diameter (d/D) ratio of small simple craters (200-1000 m) of an area between -88.5 degrees to -90 degrees latitude at the lunar south pole containing Permanent Shadowed Regions (PSRs) versus craters without PSRs. As PSRs can reach temperatures of 110 K and are capable of harboring volatiles, especially water ice, we analyzed the relationship of depth versus diameter ratios and its possible implications for harboring water ice. Variations in the d/D ratios can also be caused by other processes such as degradation, isostatic adjustment, or differences in surface properties. The conducted d/D ratio analysis suggests that a differentiation between craters containing PSRs versus craters without PSRs occurs. Thus, a possible direct relation between d/D ratio, PSRs, and water ice harboring might exist. Our results suggest that differences in the target's surface properties may explain the obtained results. The resulting d/D ratios of craters with PSRs can help to select target areas for future In-Situ Resource Utilization (ISRU) missions. KW - craters KW - lunar exploration KW - ice harboring Y1 - 2022 U6 - https://doi.org/10.3390/rs14030450 SN - 2072-4292 VL - 14 IS - 3 PB - MDPI CY - Basel ER - TY - JOUR A1 - Mohr, Bettina T1 - Depressive Erkrankungen bei Aphasie BT - Intensive sprachtherapeutische und multidisziplinäre Behandlungsansätze JF - Spektrum Patholinguistik 15 Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-572330 SN - 978-3-86956-542-2 SN - 1866-9433 SN - 1866-9085 IS - 15 SP - 21 EP - 25 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Boeker, Sonja A1 - Hermanussen, Michael A1 - Scheffler, Christiane T1 - Dental age is an independent marker of biological age JF - Human biology and public health N2 - Background: Biological age markers are a crucial indicator whether children are decelerated in growth tempo. Skeletal maturation is the standard measure. Yet, it relies on exposing children to x-radiation. Dental eruption is a potential, but highly debated, radiation free alternative.  Objectives: We assess the interrelationship between dental eruption and other maturational markers. We hypothesize that dental age correlates with body height and skeletal age. We further evaluate how the three different variables behave in cohorts from differing social backgrounds. Sample and Method: Dental, skeletal and height data from the 1970s to 1990s from Guatemalan boys were converted into standard deviation scores, using external references for each measurement. The boys, aged between 7 and 12, derived from different social backgrounds (middle SES (N = 6529), low-middle SES (N = 736), low SES Ladino (N = 3653) and low SES Maya (N = 4587). Results: Dental age shows only a weak correlation with skeletal age (0.18) and height (0.2). The distinction between cohorts differs according to each of the three measurements. All cohorts differ significantly in height. In skeletal maturation, the middle SES cohort is significantly advanced compared to all other cohorts. The periodically malnourished cohorts of low SES Mayas and Ladinos are significantly delayed in dental maturation compared to the well-nourished low-middle and middle class Ladino children. Conclusion: Dental development is an independent system, that is regulated by different mechanisms than skeletal development and growth. Tooth eruption is sensitive to nutritional status, whereas skeletal age is more sensitive to socioeconomic background. KW - dental eruption KW - biological age KW - skeletal age KW - growth tempo KW - maturation KW - malnutrition Y1 - 2022 U6 - https://doi.org/10.52905/hbph2021.3.24 SN - 2748-9957 VL - 2021 IS - 3, Summer School Supplement PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Spooner, Cameron A1 - Scheck-Wenderoth, Magdalena A1 - Götze, Hans-Jürgen A1 - Ebbing, Jörg A1 - Hetenyi, Gyoergy T1 - Density distribution across the Alpine lithosphere constrained by 3-D gravity modelling and relation to seismicity and deformation JF - Solid earth N2 - The Alpine orogen formed as a result of the collision between the Adriatic and European plates. Significant crustal heterogeneity exists within the region due to the long history of interplay between these plates, other continental and oceanic blocks in the region, and inherited crustal features from earlier orogenies. Deformation relating to the collision continues to the present day. Here, a seismically constrained, 3-D structural and density model of the lithosphere of the Alps and their respective forelands, derived from integrating numerous geoscientific datasets, was adjusted to match the observed gravity field. It is shown that the distribution of seismicity and deformation within the region correlates well to thickness and density changes within the crust, and that the present-day Adriatic crust is both thinner and denser (22.5 km, 2800 kg m(-3) ) than the European crust (27.5 km, 2750 kg m(-3)). Alpine crust derived from each respective plate is found to show the same trend, with zones of Adriatic provenance (Austro-Alpine unit and Southern Alps) found to be denser and those of European provenance (Helvetic zone and Tauern Window) to be less dense. This suggests that the respective plates and related terranes had similar crustal properties to the present-day ones prior to orogenesis. The model generated here is available for open-access use to further discussions about the crust in the region. Y1 - 2019 U6 - https://doi.org/10.5194/se-10-2073-2019 SN - 1869-9510 SN - 1869-9529 VL - 10 IS - 6 SP - 2073 EP - 2088 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Thomas, Jessica E. A1 - Carvalho, Gary R. A1 - Haile, James A1 - Rawlence, Nicolas J. A1 - Martin, Michael D. A1 - Ho, Simon Y. W. A1 - Sigfusson, Arnor P. A1 - Josefsson, Vigfus A. A1 - Frederiksen, Morten A1 - Linnebjerg, Jannie F. A1 - Castruita, Jose A. Samaniego A1 - Niemann, Jonas A1 - Sinding, Mikkel-Holger S. A1 - Sandoval-Velasco, Marcela A1 - Soares, Andre E. R. A1 - Lacy, Robert A1 - Barilaro, Christina A1 - Best, Juila A1 - Brandis, Dirk A1 - Cavallo, Chiara A1 - Elorza, Mikelo A1 - Garrett, Kimball L. A1 - Groot, Maaike A1 - Johansson, Friederike A1 - Lifjeld, Jan T. A1 - Nilson, Goran A1 - Serjeanston, Dale A1 - Sweet, Paul A1 - Fuller, Errol A1 - Hufthammer, Anne Karin A1 - Meldgaard, Morten A1 - Fjeldsa, Jon A1 - Shapiro, Beth A1 - Hofreiter, Michael A1 - Stewart, John R. A1 - Gilbert, M. Thomas P. A1 - Knapp, Michael T1 - Demographic reconstruction from ancient DNA supports rapid extinction of the great auk JF - eLife N2 - The great auk was once abundant and distributed across the North Atlantic. It is now extinct, having been heavily exploited for its eggs, meat, and feathers. We investigated the impact of human hunting on its demise by integrating genetic data, GPS-based ocean current data, and analyses of population viability. We sequenced complete mitochondrial genomes of 41 individuals from across the species' geographic range and reconstructed population structure and population dynamics throughout the Holocene. Taken together, our data do not provide any evidence that great auks were at risk of extinction prior to the onset of intensive human hunting in the early 16th century. In addition, our population viability analyses reveal that even if the great auk had not been under threat by environmental change, human hunting alone could have been sufficient to cause its extinction. Our results emphasise the vulnerability of even abundant and widespread species to intense and localised exploitation. Y1 - 2019 U6 - https://doi.org/10.7554/eLife.47509 SN - 2050-084X VL - 8 PB - eLife Sciences Publications CY - Cambridge ER - TY - JOUR A1 - Hanisch, Xenia ED - Ambühl, Annemarie ED - Carlà-Uhink, Filippo ED - Rollinger, Christian ED - Walde, Christine T1 - Demagogen dichten BT - Antike Szenen als Gegenstand moderner Gedankenexperimente JF - thersites 14 N2 - Manipulative rhetoric is a common issue in ancient sources. As the issue of political populism and rhetoric still attracts a high degree of interest among a wide range of people, the author, a singer-songwriter, attempts to ‘revive’ these ancient sources and to adapt them into a lyrical/musical format for modern audiences, in order to test different strategies of manipulation and gauge the reactions of modern audiences. The following article describes the process of adapting and performing two of these experiments, as well as the results and feedback from audiences. The ancient case studies chosen for this are Thucydides’ description of how Alcibiades lead the Athenians into a fatal expedition to Sicily, and Xenophon’s blames of two public orators for executing Athenian generals after the battle of Arginusae through their manipulative speeches. Y1 - 2022 U6 - https://doi.org/10.34679/thersites.vol14.201 SN - 2364-7612 VL - 2022 IS - 14 SP - 121 EP - 140 ER - TY - JOUR A1 - Schachner, Theresa A1 - Gross, Christoph A1 - Hasl, Andrea A1 - Wangenheim, Florian von A1 - Kowatsch, Tobias T1 - Deliberative and paternalistic interaction styles for conversational agents in digital health BT - procedure and validation through a web-based experiment JF - Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR N2 - Background: Recent years have witnessed a constant increase in the number of people with chronic conditions requiring ongoing medical support in their everyday lives. However, global health systems are not adequately equipped for this extraordinarily time-consuming and cost-intensive development. Here, conversational agents (CAs) can offer easily scalable and ubiquitous support. Moreover, different aspects of CAs have not yet been sufficiently investigated to fully exploit their potential. One such trait is the interaction style between patients and CAs. In human-to-human settings, the interaction style is an imperative part of the interaction between patients and physicians. Patient-physician interaction is recognized as a critical success factor for patient satisfaction, treatment adherence, and subsequent treatment outcomes. However, so far, it remains effectively unknown how different interaction styles can be implemented into CA interactions and whether these styles are recognizable by users. Objective: The objective of this study was to develop an approach to reproducibly induce 2 specific interaction styles into CA-patient dialogs and subsequently test and validate them in a chronic health care context. Methods: On the basis of the Roter Interaction Analysis System and iterative evaluations by scientific experts and medical health care professionals, we identified 10 communication components that characterize the 2 developed interaction styles: deliberative and paternalistic interaction styles. These communication components were used to develop 2 CA variations, each representing one of the 2 interaction styles. We assessed them in a web-based between-subject experiment. The participants were asked to put themselves in the position of a patient with chronic obstructive pulmonary disease. These participants were randomly assigned to interact with one of the 2 CAs and subsequently asked to identify the respective interaction style. Chi-square test was used to assess the correct identification of the CA-patient interaction style. Results: A total of 88 individuals (42/88, 48% female; mean age 31.5 years, SD 10.1 years) fulfilled the inclusion criteria and participated in the web-based experiment. The participants in both the paternalistic and deliberative conditions correctly identified the underlying interaction styles of the CAs in more than 80% of the assessments (X-1(,8)8(2)=38.2; P<.001; phi coefficient r(phi)=0.68). The validation of the procedure was hence successful. Conclusions: We developed an approach that is tailored for a medical context to induce a paternalistic and deliberative interaction style into a written interaction between a patient and a CA. We successfully tested and validated the procedure in a web-based experiment involving 88 participants. Future research should implement and test this approach among actual patients with chronic diseases and compare the results in different medical conditions. This approach can further be used as a starting point to develop dynamic CAs that adapt their interaction styles to their users. KW - conversational agents KW - chatbots KW - human-computer interaction KW - physician-patient relationship KW - interaction styles KW - deliberative KW - interaction KW - paternalistic interaction KW - digital health KW - chronic KW - conditions KW - COPD Y1 - 2021 U6 - https://doi.org/10.2196/22919 SN - 1438-8871 VL - 23 IS - 1 PB - Healthcare World CY - Richmond, Va. ER - TY - JOUR A1 - Ritterbusch, Georg David A1 - Teichmann, Malte Rolf T1 - Defining the metaverse BT - A systematic literature review JF - IEEE Access N2 - The term Metaverse is emerging as a result of the late push by multinational technology conglomerates and a recent surge of interest in Web 3.0, Blockchain, NFT, and Cryptocurrencies. From a scientific point of view, there is no definite consensus on what the Metaverse will be like. This paper collects, analyzes, and synthesizes scientific definitions and the accompanying major characteristics of the Metaverse using the methodology of a Systematic Literature Review (SLR). Two revised definitions for the Metaverse are presented, both condensing the key attributes, where the first one is rather simplistic holistic describing “a three-dimensional online environment in which users represented by avatars interact with each other in virtual spaces decoupled from the real physical world”. In contrast, the second definition is specified in a more detailed manner in the paper and further discussed. These comprehensive definitions offer specialized and general scholars an application within and beyond the scientific context of the system science, information system science, computer science, and business informatics, by also introducing open research challenges. Furthermore, an outlook on the social, economic, and technical implications is given, and the preconditions that are necessary for a successful implementation are discussed. KW - Metaverse KW - Systematics KW - Bibliometrics KW - Augmented reality KW - Taxonomy KW - Semantic Web KW - Second Life KW - Blockchains KW - Economics Y1 - 2023 U6 - https://doi.org/10.1109/ACCESS.2023.3241809 SN - 2169-3536 VL - 11 SP - 12368 EP - 12377 PB - Institute of Electrical and Electronics Engineers CY - New York, NY ER - TY - JOUR A1 - Ziegler, Joceline A1 - Pfitzner, Bjarne A1 - Schulz, Heinrich A1 - Saalbach, Axel A1 - Arnrich, Bert T1 - Defending against Reconstruction Attacks through Differentially Private Federated Learning for Classification of Heterogeneous Chest X-ray Data JF - Sensors N2 - Privacy regulations and the physical distribution of heterogeneous data are often primary concerns for the development of deep learning models in a medical context. This paper evaluates the feasibility of differentially private federated learning for chest X-ray classification as a defense against data privacy attacks. To the best of our knowledge, we are the first to directly compare the impact of differentially private training on two different neural network architectures, DenseNet121 and ResNet50. Extending the federated learning environments previously analyzed in terms of privacy, we simulated a heterogeneous and imbalanced federated setting by distributing images from the public CheXpert and Mendeley chest X-ray datasets unevenly among 36 clients. Both non-private baseline models achieved an area under the receiver operating characteristic curve (AUC) of 0.940.94 on the binary classification task of detecting the presence of a medical finding. We demonstrate that both model architectures are vulnerable to privacy violation by applying image reconstruction attacks to local model updates from individual clients. The attack was particularly successful during later training stages. To mitigate the risk of a privacy breach, we integrated Rényi differential privacy with a Gaussian noise mechanism into local model training. We evaluate model performance and attack vulnerability for privacy budgets ε∈{1,3,6,10}�∈{1,3,6,10}. The DenseNet121 achieved the best utility-privacy trade-off with an AUC of 0.940.94 for ε=6�=6. Model performance deteriorated slightly for individual clients compared to the non-private baseline. The ResNet50 only reached an AUC of 0.760.76 in the same privacy setting. Its performance was inferior to that of the DenseNet121 for all considered privacy constraints, suggesting that the DenseNet121 architecture is more robust to differentially private training. KW - federated learning KW - privacy and security KW - privacy attack KW - X-ray Y1 - 2022 U6 - https://doi.org/10.3390/s22145195 SN - 1424-8220 VL - 22 PB - MDPI CY - Basel, Schweiz ET - 14 ER - TY - JOUR A1 - Kayhan, Ezgi A1 - Matthes, Daniel A1 - Marriott Haresign, Ira A1 - Bánki, Anna A1 - Michel, Christine A1 - Langeloh, Miriam A1 - Wass, Sam A1 - Hoehl, Stefanie T1 - DEEP: A dual EEG pipeline for developmental hyperscanning studies JF - Developmental Cognitive Neuroscience N2 - Cutting-edge hyperscanning methods led to a paradigm shift in social neuroscience. It allowed researchers to measure dynamic mutual alignment of neural processes between two or more individuals in naturalistic contexts. The ever-growing interest in hyperscanning research calls for the development of transparent and validated data analysis methods to further advance the field. We have developed and tested a dual electroencephalography (EEG) analysis pipeline, namely DEEP. Following the preprocessing of the data, DEEP allows users to calculate Phase Locking Values (PLVs) and cross-frequency PLVs as indices of inter-brain phase alignment of dyads as well as time-frequency responses and EEG power for each participant. The pipeline also includes scripts to control for spurious correlations. Our goal is to contribute to open and reproducible science practices by making DEEP publicly available together with an example mother-infant EEG hyperscanning dataset. KW - Developmental hyperscanning KW - Dual EEG analysis KW - Adult-child interaction KW - Phase Locking Value KW - PLV KW - Cross-frequency PLV KW - FieldTrip Y1 - 2022 U6 - https://doi.org/10.1016/j.dcn.2022.101104 SN - 1878-9307 VL - 54 SP - 1 EP - 11 PB - Elsevier CY - Amsterdam, Niederlande ER - TY - JOUR A1 - De Lucia, Marco A1 - Kühn, Michael T1 - DecTree v1.0-chemistry speedup in reactive transport simulations BT - purely data-driven and physics-based surrogates JF - Geoscientific model development : an interactive open access journal of the European Geosciences Union N2 - The computational costs associated with coupled reactive transport simulations are mostly due to the chemical subsystem: replacing it with a pre-trained statistical surrogate is a promising strategy to achieve decisive speedups at the price of small accuracy losses and thus to extend the scale of problems which can be handled. We introduce a hierarchical coupling scheme in which "full-physics" equation-based geochemical simulations are partially replaced by surrogates. Errors in mass balance resulting from multivariate surrogate predictions effectively assess the accuracy of multivariate regressions at runtime: inaccurate surrogate predictions are rejected and the more expensive equation-based simulations are run instead. Gradient boosting regressors such as XGBoost, not requiring data standardization and being able to handle Tweedie distributions, proved to be a suitable emulator. Finally, we devise a surrogate approach based on geochemical knowledge, which overcomes the issue of robustness when encountering previously unseen data and which can serve as a basis for further development of hybrid physics-AI modelling. Y1 - 2021 U6 - https://doi.org/10.5194/gmd-14-4713-2021 SN - 1991-959X SN - 1991-9603 VL - 14 IS - 7 SP - 4713 EP - 4730 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Kluth, Oliver A1 - Stadion, Mandy A1 - Gottmann, Pascal A1 - Aga-Barfknecht, Heja A1 - Jähnert, Markus A1 - Scherneck, Stephan A1 - Vogel, Heike A1 - Krus, Ulrika A1 - Seelig, Anett A1 - Ling, Charlotte A1 - Gerdes, Jantje A1 - Schürmann, Annette T1 - Decreased expression of cilia genes in pancreatic islets as a risk factor for type 2 diabetes in mice and humans JF - Cell reports N2 - An insufficient adaptive beta-cell compensation is a hallmark of type 2 diabetes (T2D). Primary cilia function as versatile sensory antennae regulating various cellular processes, but their role on compensatory beta-cell replication has not been examined. Here, we identify a significant enrichment of downregulated, cilia-annotated genes in pancreatic islets of diabetes-prone NZO mice as compared with diabetes-resistant B6-ob/ob mice. Among 327 differentially expressed mouse cilia genes, 81 human orthologs are also affected in islets of diabetic donors. Islets of nondiabetic mice and humans show a substantial overlap of upregulated cilia genes that are linked to cell-cycle progression. The shRNA-mediated suppression of KIF3A, essential for ciliogenesis, impairs division of MINE beta cells as well as in dispersed primary mouse and human islet cells, as shown by decreased BrdU incorporation. These findings demonstrate the substantial role of cilia-gene regulation on islet function and T2D risk. Y1 - 2019 U6 - https://doi.org/10.1016/j.celrep.2019.02.056 SN - 2211-1247 VL - 26 IS - 11 SP - 3027 EP - 3036 PB - Cell Press CY - Maryland Heights ER - TY - JOUR A1 - Heidler, Maria-Dorothea A1 - Salzwedel, Annett A1 - Jöbges, Michael A1 - Lück, Olaf A1 - Dohle, Christian A1 - Seifert, Michael A1 - von Helden, Andrea A1 - Hollweg, Wibke A1 - Völler, Heinz T1 - Decannulation of tracheotomized patients after long-term mechanical ventilation - results of a prospective multicentric study in German neurological early rehabilitation hospitals JF - BMC Anesthesiology N2 - Background: In the course of neurological early rehabilitation, decannulation is attempted in tracheotomized patients after weaning due to its considerable prognostic significance. We aimed to identify predictors of a successful tracheostomy decannulation. Methods: From 09/2014 to 03/2016, 831 tracheotomized and weaned patients (65.4 +/- 12.9 years, 68% male) were included consecutively in a prospective multicentric observation study. At admission, sociodemographic and clinical data (e.g. relevant neurological and internistic diseases, duration of mechanical ventilation, tracheotomy technique, and nutrition) as well as functional assessments (Coma Recovery Scale-Revised (CRS-R), Early Rehabilitation Barthel Index, Bogenhausener Dysphagia Score) were collected. Complications and the success of the decannulation procedure were documented at discharge. Results: Four hundred seventy patients (57%) were decannulated. The probability of decannulation was significantly negatively associated with increasing age (OR 0.68 per SD = 12.9 years, p < 0.001), prolonged duration of mechanical ventilation (OR 0.57 per 33.2 days, p < 0.001) and complications. An oral diet (OR 3.80; p < 0.001) and a higher alertness at admission (OR 3.07 per 7.18 CRS-R points; p < 0.001) were positively associated. Conclusions: This study identified practically measurable predictors of decannulation, which in the future can be used for a decannulation prognosis and supply optimization at admission in the neurological early rehabilitation clinic. KW - Mechanical ventilation KW - Tracheostomy KW - Decannulation KW - Prognosis Y1 - 2018 U6 - https://doi.org/10.1186/s12871-018-0527-3 SN - 1471-2253 VL - 18 PB - BMC CY - London ER - TY - JOUR A1 - Khudair, Mohammed A1 - Marcuzzi, Anna A1 - Ng, Kwok A1 - Tempest, Gavin Daniel A1 - Bartoš, František A1 - Peric, Ratko A1 - Maier, Maximilian A1 - Beccia, Flavia A1 - Boccia, Stefania A1 - Brandes, Mirko A1 - Cardon, Greet A1 - Carlin, Angela A1 - Castagna, Carolina A1 - Chaabene, Helmi A1 - Chalkley, Anna A1 - Ciaccioni, Simone A1 - Cieślińska-Świder, Joanna A1 - Čingienė, Vilma A1 - Cortis, Cristina A1 - Corvino, Chiara A1 - de Geus, Eco J. C. A1 - Di Baldassarre, Angela A1 - Di Credico, Andrea A1 - Drid, Patrik A1 - Tarazaga, Rosa Ma Fernández A1 - Gallè, Francesca A1 - Sánchez, Esther Garcia A1 - Gebremariam, Mekdes A1 - Ghinassi, Barbara A1 - Goudas, Marios A1 - Hayes, Grainne A1 - Honorio, Samuel A1 - Izzicupo, Pascal A1 - Jahre, Henriette A1 - Jelsma, Judith A1 - Juric, Petra A1 - Kolovelonis, Athanasios A1 - Kongsvold, Atle A1 - Kouidi, Evangelia A1 - Mansergh, Fiona A1 - Masanovic, Bojan A1 - Mekonnen, Teferi A1 - Mork, Paul Jarle A1 - Murphy, Marie A1 - O'Hara, Kelly A1 - Torun, Ayse Ozbil A1 - Palumbo, Federico A1 - Popovic, Stevo A1 - Prieske, Olaf A1 - Puharic, Zrinka A1 - Ribeiro, José Carlos A1 - Rumbold, Penny Louise Sheena A1 - Sandu, Petru A1 - Soric, Maroje A1 - Stavnsbo, Mette A1 - Syrmpas, Ioannis A1 - van der Ploeg, Hidde P. A1 - Van Hoye, Aurélie A1 - Vilela, Sofia A1 - Woods, Catherine A1 - Wunsch, Kathrin A1 - Caprinica, Laura A1 - MacDonncha, Ciaran A1 - Ling, Fiona Chun Man T1 - DE-PASS Best Evidence Statement (BESt): modifiable determinants of physical activity and sedentary behaviour in children and adolescents aged 5-19 years-a protocol for systematic review and meta-analysis JF - BMJ open N2 - Introduction Physical activity among children and adolescents remains insufficient, despite the substantial efforts made by researchers and policymakers. Identifying and furthering our understanding of potential modifiable determinants of physical activity behaviour (PAB) and sedentary behaviour (SB) is crucial for the development of interventions that promote a shift from SB to PAB. The current protocol details the process through which a series of systematic literature reviews and meta-analyses (MAs) will be conducted to produce a best-evidence statement (BESt) and inform policymakers. The overall aim is to identify modifiable determinants that are associated with changes in PAB and SB in children and adolescents (aged 5-19 years) and to quantify their effect on, or association with, PAB/SB. Methods and analysis A search will be performed in MEDLINE, SportDiscus, Web of Science, PsychINFO and Cochrane Central Register of Controlled Trials. Randomised controlled trials (RCTs) and controlled trials (CTs) that investigate the effect of interventions on PAB/SB and longitudinal studies that investigate the associations between modifiable determinants and PAB/SB at multiple time points will be sought. Risk of bias assessments will be performed using adapted versions of Cochrane's RoB V.2.0 and ROBINS-I tools for RCTs and CTs, respectively, and an adapted version of the National Institute of Health's tool for longitudinal studies. Data will be synthesised narratively and, where possible, MAs will be performed using frequentist and Bayesian statistics. Modifiable determinants will be discussed considering the settings in which they were investigated and the PAB/SB measurement methods used. Ethics and dissemination No ethical approval is needed as no primary data will be collected. The findings will be disseminated in peer-reviewed publications and academic conferences where possible. The BESt will also be shared with policy makers within the DE-PASS consortium in the first instance. Systematic review registration CRD42021282874. KW - public health KW - health policy KW - community child health Y1 - 2022 U6 - https://doi.org/10.1136/bmjopen-2021-059202 SN - 2044-6055 VL - 12 IS - 9 PB - BMJ Publishing Group CY - London ER - TY - JOUR A1 - Unceta Gómez, Luis A1 - Carlà-Uhink, Filippo A1 - Freitag, Florian ED - Ambühl, Annemarie ED - Carlà-Uhink, Filippo ED - Rollinger, Christian ED - Walde, Christine T1 - De héroes y efebos. El mundo clásico en la fotografía de desnudo masculino contemporáneo. Entrevista a Carmelo Blázquez JF - thersites 14 N2 - Entrevista a Carmelo Blázquez, fotógrafo especializado en fotografía de desnudo masculino, que trabaja con motivos y modelos procedentes de la Antigüedad grecolatina. Y1 - 2022 U6 - https://doi.org/10.34679/thersites.vol14.208 SN - 2364-7612 VL - 2022 IS - 14 SP - 103 EP - 120 ER - TY - JOUR A1 - Ette, Ottmar T1 - De cómicos e histéricos BT - Una réplica a la sátira sobre eruditos de Daniel Kehlmann N2 - La popularidad de Alejandro de Humboldt ha cambiado profundamente dentro del último cuarto de siglo en la opinión pública de habla alemana. Prueba de esto son no sólo las encuestas televisivas sobre los alemanes más famosos, dentro de las cuales figura en estos momentos Alejandro de Humboldt, o programas de televisión sobre expediciones actuales, en los que continuamente se retoma el nombre de Humboldt; quizás la comprobación más clara de este cambio es el éxito enorme de la novela Die Vermessung der Welt de Daniel Kehlmann. Éxito que sería impensable sin el proceso esbozado más arriba. Ante este trasfondo, estudiar el gran éxito de esta pequeña novela resulta no sólo atractivo, sino además revelador. ¿De qué se trata Die Vermessung der Welt? ¿Cómo se puede explicar el »fenómeno Kehlmann« desde una distancia relativamente mayor? N2 - Wie stark sich im Verlauf des zurückliegenden Vierteljahrhunderts der Bekanntheitsgrad Alexander von Humboldts in der deutschsprachigen Öffentlichkeit verändert hat, zeigen nicht nur Fernsehumfragen zu den berühmtesten Deutschen, in denen Alexander von Humboldt mittlerweile figuriert, oder Fernsehserien, die über aktuelle Expeditionen berichten und auf Humboldts Namen zurückgreifen. Am deutlichsten vielleicht belegt dies der enorme Erfolg von Daniel Kehlmanns Roman Die Vermessung der Welt, der ohne die zuvor skizzierte Entwicklung nicht denkbar gewesen wäre. Es ist vor diesem Hintergrund nicht nur reizvoll, sondern aufschlußreich, sich mit dem großen Erfolg dieses kleinen Romans zu beschäftigen. Worum geht es in Die Vermessung der Welt? Und wie läßt sich das »Phänomen Kehlmann« aus etwas größerer Distanz erklären? N2 - In the last 25 years, Alexander von Humboldt‘s popularity has radically changed in the german-speaking public opinion. Proof of this are not only television surveys about the most famous germans - in which Alexander von Humboldt now regularly figures - or television series about contemporary expeditions, which constantly refer to Humboldt‘s name; perhaps what most clearly verifies this change is the great success of Daniel Kehlmann‘s novel Die Vermessung der Welt. Without the recent developments outlined above, this novel‘s degree of impact would have been unimaginable. To study the great success of this text against this backdrop is not only attractive, but also revealing. What is Die Vermessung der Welt really about? And how can we explain this »Kehlmann phenomenon« from a greater distance? KW - Carl Friedrich Gauß KW - Daniel Kehlmann KW - Die Vermessung der Welt KW - Schwerpunktthema „À propos Kehlmann“ Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62406 SN - 1617-5239 SN - 2568-3543 VL - XIII IS - 25 SP - 41 EP - 45 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Jobe, Jessica Ann Thompson A1 - Li, Tao A1 - Bookhagen, Bodo A1 - Chen, Jie A1 - Burbank, Douglas W. T1 - Dating growth strata and basin fill by combining Al-26/Be-10 burial dating and magnetostratigraphy BT - Constraining active deformation in the Pamir-Tian Shan convergence zone, NW China JF - Lithosphere N2 - Cosmogenic burial dating enables dating of coarse-grained, Pliocene-Pleistocene sedimentary units that are typically difficult to date with traditional methods, such as magnetostratigraphy. In the actively deforming western Tarim Basin in NW China, Pliocene-Pleistocene conglomerates were dated at eight sites, integrating Al-26/Be-10 burial dating with previously published magnetostratigraphic sections. These samples were collected from growth strata on the flanks of growing folds and from sedimentary units beneath active faults to place timing constraints on the initiation of deformation of structures within the basin and on shortening rates on active faults. These new basin-fill and growthstrata ages document the late Neogene and Quaternary growth of the Pamir and Tian Shan orogens between >5 and 1 Ma and delineate the eastward propagation of deformation at rates up to 115 km/m.y. and basinward growth of both mountain belts at rates up to 12 km/m.y. Y1 - 2018 U6 - https://doi.org/10.1130/L727.1 SN - 1941-8264 SN - 1947-4253 VL - 10 IS - 6 SP - 806 EP - 828 PB - American Institute of Physics CY - Boulder ER - TY - JOUR A1 - Kindermann, Liana A1 - Dobler, Magnus A1 - Niedeggen, Daniela A1 - Chimbioputo Fabiano, Ezequiel A1 - Linstädter, Anja T1 - Dataset on woody aboveground biomass, disturbance losses, and wood density from an African savanna ecosystem JF - Data in Brief N2 - This dataset comprises tree inventories and damage assessments performed in Namibia's semi-arid Zambezi Region. Data were sampled in savannas and savanna woodlands along steep gradients of elephant population densities to capture the effects of those (and other) disturbances on individual-level and stand-level aboveground woody biomass (AGB). The dataset contains raw data on dendrometric measures and processed data on specific wood density (SWD), woody aboveground biomass, and biomass losses through disturbance impacts. Allometric proxies (height, canopy diameters, and in adult trees also stem circumferences) were recorded for n = 6,179 tree and shrub individuals. Wood samples were taken for each encountered species to measure specific wood density. These measurements have been used to estimate woody aboveground biomass via established allometric models, advanced through our improved methodologies and workflows that accounted for tree and shrub architecture shaped by disturbance impacts. To this end, we performed a detailed damage assessment on each woody individual in the field. In addition to estimations of standing biomass, our new method also delivered data on biomass losses to different disturbance agents (elephants, fire, and others) on the level of plant individuals and stands. The data presented here have been used within a study published with Ecological Indicators (Kindermann et al., 2022) to evaluate the benefits of our improved methodology in comparison to a standard reference method of aboveground biomass estimations. Additionally, it has been employed in a study on carbon storage and sequestration in vegetation and soils (Sandhage-Hofmann et al., 2021). The raw data of dendrometric measurements can be subjected to other available allometric models for biomass estimation. The processed data can be used to analyze disturbance impacts on woody aboveground biomass, or for regional carbon storage estimates. The data on species-specific wood density can be used for application to other dendrometric datasets to (re-) estimate biomass through allometric models requiring wood density. It can further be used for plant functional trait analyses. KW - Damage assessment KW - Disturbance impacts KW - Disturbance indicator KW - Elephant disturbance KW - Tree allometry KW - Specific wood density KW - Woody aboveground biomass KW - Wood specific gravity Y1 - 2022 U6 - https://doi.org/10.1016/j.dib.2022.108155 SN - 2352-3409 VL - 42 SP - 1 EP - 16 PB - Elsevier CY - Amsterdam, Niederlande ER - TY - JOUR A1 - Baumgart, Lene A1 - Boos, Pauline A1 - Eckstein, Bernd T1 - Datafication and algorithmic contingency BT - how agile organisations deal with technical systems JF - Work organisation, labour & globalisation N2 - In the context of persistent images of self-perpetuated technologies, we discuss the interplay of digital technologies and organisational dynamics against the backdrop of systems theory. Building on the case of an international corporation that, during an agile reorganisation, introduced an AI-based personnel management platform, we show how technical systems produce a form of algorithmic contingency that subsequently leads to the emergence of formal and informal interaction systems. Using the concept of datafication, we explain how these interactions are barriers to the self-perpetuation of data-based decision-making, making it possible to take into consideration further decision factors and complementing the output of the platform. The research was carried out within the scope of the research project ‘Organisational Implications of Digitalisation: The Development of (Post-)Bureaucratic Organisational Structures in the Context of Digital Transformation’ funded by the German Research Foundation (DFG). KW - digitalisation KW - datafication KW - organisation KW - agile KW - technical system KW - systems theory KW - interaction KW - algorithmic contingency KW - machine learning KW - platform Y1 - 2023 U6 - https://doi.org/10.13169/workorgalaboglob.17.1.0061 SN - 1745-641X SN - 1745-6428 VL - 17 IS - 1 SP - 61 EP - 73 PB - Pluto Journals CY - London ER - TY - JOUR A1 - Petrov, Polina A1 - Singer, Leo P. A1 - Coughlin, Michael W. A1 - Kumar, Vishwesh A1 - Almualla, Mouza A1 - Anand, Shreya A1 - Bulla, Mattia A1 - Dietrich, Tim A1 - Foucart, Francois A1 - Guessoum, Nidhal T1 - Data-driven expectations for electromagnetic counterpart searches based on LIGO/Virgo public alerts JF - The astrophysical journal : an international review of spectroscopy and astronomical physics; part 1 N2 - Searches for electromagnetic counterparts of gravitational-wave signals have redoubled since the first detection in 2017 of a binary neutron star merger with a gamma-ray burst, optical/infrared kilonova, and panchromatic afterglow. Yet, one LIGO/Virgo observing run later, there has not yet been a second, secure identification of an electromagnetic counterpart. This is not surprising given that the localization uncertainties of events in LIGO and Virgo's third observing run, O3, were much larger than predicted. We explain this by showing that improvements in data analysis that now allow LIGO/Virgo to detect weaker and hence more poorly localized events have increased the overall number of detections, of which well-localized, gold-plated events make up a smaller proportion overall. We present simulations of the next two LIGO/Virgo/KAGRA observing runs, O4 and O5, that are grounded in the statistics of O3 public alerts. To illustrate the significant impact that the updated predictions can have, we study the follow-up strategy for the Zwicky Transient Facility. Realistic and timely forecasting of gravitational-wave localization accuracy is paramount given the large commitments of telescope time and the need to prioritize which events are followed up. We include a data release of our simulated localizations as a public proposal planning resource for astronomers. Y1 - 2022 U6 - https://doi.org/10.3847/1538-4357/ac366d SN - 1538-4357 VL - 924 IS - 2 PB - Institute of Physics Publ. CY - London ER - TY - JOUR A1 - Schwahn, Kevin A1 - Nikoloski, Zoran T1 - Data reduction approaches for dissecting transcriptional effects on metabolism JF - Frontiers in plant science N2 - The availability of high-throughput data from transcriptomics and metabolomics technologies provides the opportunity to characterize the transcriptional effects on metabolism. Here we propose and evaluate two computational approaches rooted in data reduction techniques to identify and categorize transcriptional effects on metabolism by combining data on gene expression and metabolite levels. The approaches determine the partial correlation between two metabolite data profiles upon control of given principal components extracted from transcriptomics data profiles. Therefore, they allow us to investigate both data types with all features simultaneously without doing preselection of genes. The proposed approaches allow us to categorize the relation between pairs of metabolites as being under transcriptional or post-transcriptional regulation. The resulting classification is compared to existing literature and accumulated evidence about regulatory mechanism of reactions and pathways in the cases of Escherichia coil, Saccharomycies cerevisiae, and Arabidopsis thaliana. KW - E. coil KW - S. cerevisiae KW - A. thaliana KW - partial correlation KW - principal component analysis KW - metabolomics KW - data reduction KW - regulation Y1 - 2018 U6 - https://doi.org/10.3389/fpls.2018.00538 SN - 1664-462X VL - 9 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Puppe, Daniel A1 - Wanner, Manfred A1 - Sommer, Michael T1 - Data on euglyphid testate amoeba densities, corresponding protozoic silicon pools, and selected soil parameters of initial and forested biogeosystems JF - Data in brief N2 - The dataset in the present article provides information on protozoic silicon (Si) pools represented by euglyphid testate amoebae (TA) in soils of initial and forested biogeosystems. Protozoic Si pools were calculated from densities of euglyphid TA shells and corresponding Si contents. The article also includes data on potential annual biosilicification rates of euglyphid TA at the examined sites. Furthermore, data on selected soil parameters (e.g., readily-available Si, soil pH) and site characteristics (e.g., soil groups, climate data) can be found. The data might be interesting for researchers focusing on biological processes in Si cycling in general and euglyphid TA and corresponding protozoic Si pools in particular. KW - Silicon cycling KW - Biogenic silica KW - Terrestrial biogeosystems KW - Biosilicification KW - Euglyphida Y1 - 2018 U6 - https://doi.org/10.1016/j.dib.2018.10.164 SN - 2352-3409 VL - 21 SP - 1697 EP - 1703 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Ullrich, André A1 - Vladova, Gergana A1 - Eigelshoven, Felix A1 - Renz, André T1 - Data mining of scientific research on artificial intelligence in teaching and administration in higher education institutions BT - a bibliometrics analysis and recommendation for future research JF - Discover artificial intelligence N2 - Teaching and learning as well as administrative processes are still experiencing intensive changes with the rise of artificial intelligence (AI) technologies and its diverse application opportunities in the context of higher education. Therewith, the scientific interest in the topic in general, but also specific focal points rose as well. However, there is no structured overview on AI in teaching and administration processes in higher education institutions that allows to identify major research topics and trends, and concretizing peculiarities and develops recommendations for further action. To overcome this gap, this study seeks to systematize the current scientific discourse on AI in teaching and administration in higher education institutions. This study identified an (1) imbalance in research on AI in educational and administrative contexts, (2) an imbalance in disciplines and lack of interdisciplinary research, (3) inequalities in cross-national research activities, as well as (4) neglected research topics and paths. In this way, a comparative analysis between AI usage in administration and teaching and learning processes, a systematization of the state of research, an identification of research gaps as well as further research path on AI in higher education institutions are contributed to research. Y1 - 2022 U6 - https://doi.org/10.1007/s44163-022-00031-7 SN - 2731-0809 VL - 2 PB - Springer CY - Cham ER - TY - JOUR A1 - Schüler, Lennart A1 - Calabrese, Justin M. A1 - Attinger, Sabine T1 - Data driven high resolution modeling and spatial analyses of the COVID-19 pandemic in Germany JF - PLoS one N2 - The SARS-CoV-2 virus has spread around the world with over 100 million infections to date, and currently many countries are fighting the second wave of infections. With neither sufficient vaccination capacity nor effective medication, non-pharmaceutical interventions (NPIs) remain the measure of choice. However, NPIs place a great burden on society, the mental health of individuals, and economics. Therefore the cost/benefit ratio must be carefully balanced and a target-oriented small-scale implementation of these NPIs could help achieve this balance. To this end, we introduce a modified SEIRD-class compartment model and parametrize it locally for all 412 districts of Germany. The NPIs are modeled at district level by time varying contact rates. This high spatial resolution makes it possible to apply geostatistical methods to analyse the spatial patterns of the pandemic in Germany and to compare the results of different spatial resolutions. We find that the modified SEIRD model can successfully be fitted to the COVID-19 cases in German districts, states, and also nationwide. We propose the correlation length as a further measure, besides the weekly incidence rates, to describe the current situation of the epidemic. Y1 - 2021 U6 - https://doi.org/10.1371/journal.pone.0254660 SN - 1932-6203 VL - 16 IS - 8 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Ghassemi, Novid A1 - Opitz, Ben A1 - Brämer, Martin A1 - Gasparjan, David A1 - Sambanis, Michaela A1 - Köster, Hilde A1 - Lücke, Martin A1 - Nordmeier, Volkhard ED - Mientus, Lukas ED - Klempin, Christiane ED - Nowak, Anna T1 - Das „Lehr-Lern-Labor“ als Lehrkonzept zur Förderung einer reflexiven Haltung bei Lehramtsstudent:nnen unterschiedlicher Fächer JF - Reflexion in der Lehrkräftebildung: Empirisch – Phasenübergreifend – Interdisziplinär (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 4) N2 - Eine reflexive Haltung gegenüber der eigenen Lehrtätigkeit gilt als Schlüsselqualifikation in Bezug auf die Professionalisierung von Lehrer:innen in allen Didaktiken (GFD, 2004, S. 4). Das universitäre Seminarformat Lehr-Lern-Labor (LLLS) kann diese Haltung fördern (Rehfeldt et al., 2018). Das Lehrformat eignet sich außerdem zur Steigerung des Professionswissens und der unterrichtlichen Handlungsfähigkeit angehender Lehrer:innen (Rehfeldt et al., 2020; Brämer & Köster, 2021). Dieser Beitrag stellt, neben der grundsätzlichen Konzeption des Seminarformats, dessen Implementierung in vier verschiedenen Fachdidaktiken (Didaktiken des Englischen, der Geschichte, der Physik und Sachunterricht und seine Didaktik) vor. Ein Fokus liegt dabei auf der unterschiedlichen Umsetzung der Reflexionsphasen. KW - Lehr-Lern-Labor-Seminar KW - Physik KW - Englisch KW - Geschichte KW - Sachunterricht Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-631924 SN - 978-3-86956-566-8 SN - 2626-3556 SN - 2626-4722 IS - 4 SP - 389 EP - 396 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Still, Melina T1 - Das Vorsorgeprinzip – ein unterschätzter Bestandteil menschenrechtlicher Klimaklagen? JF - MenschenRechtsMagazin N2 - Das Vorsorgeprinzip ist ein mittlerweile weit verbreiteter und etablierter Grundsatz des internationalen und europäischen Umweltrechts. Demnach sollen auch in Situationen wissenschaftlicher Unsicherheit präventive Maßnahmen ergriffen werden, um schwerwiegende Umweltschäden zu vermeiden. Dieser Beitrag untersucht die Rolle des Vorsorgeprinzips im Zusammenhang mit menschenrechtlichen Klimaklagen, die aufgrund langsamer politischer Fortschritte und erfolgreicher Gerichtsentscheidungen zunehmend an Popularität gewinnen. Zunächst wird ein Überblick über die Entwicklung und den materiellen Gehalt des Vorsorgeprinzips im internationalen und europäischen Recht gegeben. Obwohl das Vorsorgeprinzip seit den 1980er Jahren ein fixer Bestandteil des internationalen Umweltrechts ist, bestehen über dessen genauen Inhalt und Rechtsnatur nach wie vor Kontroversen. Im Unionsrecht wurde das Vorsorgeprinzip insbesondere durch die Rechtsprechung des EuGH konkretisiert. Im nächsten Teil des Beitrags wird beleuchtet, welche Bedeutung der EGMR dem Vorsorgeprinzip in umweltrechtlichen Fällen bisher zugemessen hat. Hierbei steht die Entscheidung Tǎtar gegen Rumänien im Mittelpunkt. Gegenstand dieser Entscheidung war der Goldabbau in der rumänischen Stadt Baia Mare, der unter anderem unter dem Einsatz von Natriumzyanid erfolgte und zu wesentlichen Schadstoffbelastungen führte. Der EGMR bejahte unter Verweis auf das Vorsorgeprinzip eine Verletzung von Art. 8 EMRK, obwohl der Beschwerdeführer die Kausalität zwischen der Schadstoffbelastung und der behaupteten Schädigung nicht nachweisen konnte. Eine Analyse der nachfolgenden Entscheidungen veranschaulicht jedoch, dass sich das Vorsorgeprinzip noch nicht als fixer Bestandteil in der Rechtsprechung des EGMR etablieren konnte. Abschließend wird gezeigt, welchen Beitrag das Vorsorgeprinzip zu der bisher wohl erfolgreichsten Klimaklage „Urgenda“ leistete. Das Vorsorgeprinzip wurde vom niederländischen Höchstgericht in diesem Fall insbesondere herangezogen, um Schutzpflichten aus Art. 2 und Art. 8 EMRK abzuleiten und den staatlichen Ermessenspielraum einzuschränken. N2 - The precautionary principle is a widely adopted and established principle of international and EU environmental law. According to this principle, precautionary measures shall be taken, even in situations of scientific uncertainty to prevent serious (environmental-)harm. This paper examines the role of the precautionary principle in the context of human rights-based climate litigation, which is becoming increasingly popular due to often slow political progress and notable judicial successes. First, an overview of the development and substantive content of the precautionary principle in international and EU law is provided. Although the precautionary principle has been an integral part of international environmental law since the 1980s, there are still controversies about its precise content and legal nature. Regarding EU law, the precautionary principle has been shaped in particular by the case law of the ECJ. In the next part of the paper, the relevance that the ECtHR has attributed to the precautionary principle in environmental law cases so far will be examined. The main focus here is on the decision Tǎtar v. Romania. In the Romanian town Baie Mare, gold mining was carried out using sodium cyanide, among other substances, which led to significant pollution. Talking into account the precautionary principle, the ECtHR ruled that there had been a violation of Art. 8 ECHR, although the complainant was unable to establish causality between the pollution and the alleged injury. However, an analysis of subsequent decisions shows that the precautionary principle has not yet become well-established aspect of ECtHR case law. Finally, the paper hightlights the contribution of the precautionary principle to the most successful climate case until now, "Urgenda”. Particularly, the Dutch Supreme Court used the precautionary principle in this case to derive duties to protect from Art. 2 and Art. 8 ECHR and to limit the state's discretion. T2 - The precautionary principle – an underestimated component of human rights-based climate litigation? Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-587852 SN - 2941-1149 VL - 28 IS - 1 SP - 27 EP - 38 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Gnädig, Susanne A1 - Seidel, Astrid A1 - Siehr, Karl-Heinz A1 - Wienecke, Maik T1 - Das Tagespraktikum im Fokus – Eine Analyse aus fachdidaktischer Sicht JF - Professionalisierung in Praxisphasen : Ergebnisse der Lehrerbildungsforschung an der Universität Potsdam (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 2) N2 - Die fachdidaktischen Tagespraktika (FTP) bilden ein Kernelement im Potsdamer Modell der Lehrerbildung, weist man ihnen doch eine „studienleitende Funktion“ zu. Wie aber realisiert sich diese Funktion in den einzelnen Fächern an der Universität Potsdam und welche Folgen ergeben sich für die Ausbildung der Lehramtsstudierenden ? Zur Beantwortung dieser Frage wurde eine Analyse der Verankerung der FTP in allen Studienordnungen hinsichtlich qualitativer (Inhalte und Ziele, Prüfungsformen, Belegungsvoraussetzungen) und quantitativer (Leistungspunkte, Semesterwochenstunden) Kriterien durchgeführt. Leitfadengestützte Interviews mit verantwortlichen Fachdidaktikerinnen und Fachdidaktikern dienten der Untersuchung der konkreten Umsetzung und der Relevanzzuschreibung. Ziel war es, durch das Zusammenführen beider Zugänge – der realiter existierenden Curricula, der individualisierten Praktiken sowie der subjektiven Überzeugungen – ein Verständnis eben jener „studienleitenden Funktion“ zu erlangen und anschließend Diskussions- und Handlungsfelder für die Weiterentwicklung des FTP herauszuarbeiten. N2 - The teaching internship (FTP) in the bachelor’s degree program has always been one core element of the Potsdam model of teacher education, which is assigned nothing less than a “study guiding function”. But how is this function interpreted and put into practice by the different departments of the University of Potsdam, and what are the consequences for the training of pre-service teachers ? In order to answer these questions, this article examines how the FTP is implemented in the study regulations with regard to qualitative criteria (contents and goals, forms of examination, requirements for enrollment) and quantitative criteria (credit points, workload). It also asks for the relevance of the FTP by conducting guided interviews with responsible lecturers. Combining both approaches – the analysis of existing curricula and the individualized practices as well as the subjective believes of the lecturers – we gain an understanding of the so-called “study guiding function” of the FTP and are thus able to elaborate areas for discussion for the development of the FTP. Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-570742 SN - 978-3-86956-508-8 SN - 2626-3556 SN - 2626-4722 IS - 2 SP - 91 EP - 121 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Ernst, Sebastian A1 - Wienecke, Maik T1 - Das Spiel mit Geschichte(n) – Computerspiele als geschichtskulturelle Erzählungen JF - DIGAREC Series N2 - Computerspiele sind wichtige und zugleich besondere geschichtskulturelle Quellen. Sie prägen in zunehmendem Maße die Vorstellungen, die wir uns von historischen Gesellschaften und Ereignissen machen. Der Geschichtsunterricht, der sich auch die Befähigung zu einem kritischen Umgang mit geschichtskulturellen Angeboten zum Ziel setzt, muss sich entsprechend mit diesen auseinandersetzen. Eine Möglichkeit, wie dies im Rahmen formaler Unterrichtsprozesse und unter Berücksichtigung der Besonderheiten dieses Mediums geschehen kann, ist Thema des folgenden Beitrags. Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-526726 SN - 978-3-86956-511-8 SN - 1867-6219 SN - 1867-6227 IS - 9 SP - 124 EP - 156 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Fuhrhop, Nanna A1 - Peters, Kendra A1 - Schreiber, Niklas T1 - Das Semikolon in Hagar Peeters’ ‚Malva‘ JF - Literarische Grammatik : wie Literatur- und Sprachwissenschaft voneinander profitieren können Y1 - 2023 SN - 978-3-8253-9504-9 SN - 978-3-8253-8608-5 U6 - https://doi.org/10.33675/2023-82538608 IS - 78 SP - 79 EP - 102 PB - Winter CY - Heidelberg ER - TY - JOUR A1 - Müller, Monika T1 - Das Schutzgesuch des Moyses Samuel BT - eine landesgeschichtliche Kommentierung JF - Genisa Blätter III KW - Genisa KW - Jüdische Studien KW - Geniza KW - Jewish Studies KW - Franken KW - Landesgeschichte KW - Ländliches Judentum KW - Franconia KW - Rural Jewry KW - regional history Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-470942 SN - 978-3-86956-470-8 SP - 59 EP - 65 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Rother, Stefanie A1 - Tosch, Frank A1 - Wendland, Mirko A1 - Kludt, Steffen T1 - Das Orientierungspraktikum in spiralcurricularer Perspektive BT - Erste Erkenntnisse der Begleitforschung zu den Schulpraktischen Studien im Potsdamer Modell der Lehrerbildung JF - Professionalisierung in Praxisphasen : Ergebnisse der Lehrerbildungsforschung an der Universität Potsdam (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 2) N2 - Das Orientierungspraktikum (OP)/Integrierte Eingangspraktikum (IEP) ist die erste schulpraktische Phase im Potsdamer Modell der Lehrerbildung. Mit diesem (Hospitations-)Praktikum (im 1. – 2. Fachsemester des Bachelorstudiums) soll der Perspektivwechsel von der Schüler:innen- zur Lehrer:innenrolle angestoßen und der Lehrer:innenberuf, die Institution Schule und der Unterricht durch eine beobachtende Perspektive reflektiert werden. Im Beitrag werden erste Ergebnisse der quantitativen und qualitativen Analyse zum OP/ IEP im Rahmen des PSI-Projekts „Kompetenzerwerb in Schulpraktischen Studien – Spiralcurriculum“ diskutiert. Aus den nachgewiesenen Effekten – u. a. Aktivierung der Reflexionsfähigkeit und Förderung der persönlichen Entwicklung – und den analysierten Bedürfnissen der Studierenden werden abschließend in zwei Diskussionssträngen „Konzeption und Handlungsrahmen“ sowie „Unterstützung und Begleitung“ Empfehlungen formuliert, die wichtige Impulse zur Weiterentwicklung des Praktikums und der begleitenden Lehrveranstaltungen liefern. N2 - The Orientation Work Placement/Integrated Introductory Work Placement is the first phase in the Potsdam Teacher Training Model during which students gain practical in-school experience. The aim of this (work shadowing) work placement (which takes place in the first two semesters of the students’ bachelor studies) is to initiate a change of perspective from the role of the student to that of the teacher, as well as reflection on teaching as a career, school as an institution, and teaching in general. In this paper, we discuss initial findings from the quantitative and qualitative analyses of the Orientation Work Placement/Integrated Introductory Work Placement within the PSI project ‘Competence Acquisition in Professional Studies – Spiral Curriculum’. Recommendations are made based on verified effects – including the activation of reflectivity and the promotion of personal development – and the analysed needs of the students are formulated into to two discussion strands: ‘Conception and Scope for Action’ and ‘Support and Supervision’. These recommendations aim to stimulate the ongoing development of work placements and their accompanying seminars. Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-570728 SN - 978-3-86956-508-8 SN - 2626-3556 SN - 2626-4722 IS - 2 SP - 31 EP - 66 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Beck, Hanno T1 - Das literarische Testament Alexander von Humboldts 1799 JF - HIN : Alexander von Humboldt im Netz ; international review for Humboldtian studies KW - Literarisches Testament KW - neu gelesen Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-70126 SN - 1617-5239 SN - 2568-3543 VL - XIV IS - 27 SP - 87 EP - 95 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Luh, Jürgen ED - Wienfort, Monika T1 - Das Jahr 1772 BT - Friedrich der Große, Polen, Spanien und die Seehandlung JF - Die Preußische Seehandlung zwischen Markt, Staat und Kultur : 40 Jahre Stiftung Preußische Seehandlung N2 - Im Jahr 1772 beschäftigten drei Dinge, die lange Zeit ihre Bedeutung behalten sollten, den preußischen König Friedrich den Großen. Zunächst war dies die Adelsrepublik Polen. Polen beabsichtigte er zusammen mit der Zarin Katharina II. von Russland und Kaiserin Maria Theresia zu zerteilen. Dies geschah am 5. August des Jahres. Der geraubte Landgewinn führte bei Friedrich II. zu wirtschaftlichen Überlegungen. Mit und in den annektierten Gebieten wollte er den preußischen Handel intensivieren, zuvörderst den Salzhandel, und zwar am liebsten mit Spanien, einem Land, mit dem er schon seit geraumer Zeit versuchte, einen Handelsvertrag abzuschließen. Dazu gründete er u. a. die Preußische Seehandlungs-Gesellschaft, die, um sich zu behaupten, verschiedene weitreichende Privilegien erhielt. Ein schneller Erfolg der Bemühungen blieb jedoch aus. Trotz aller gewährten Privilegien florierten die Geschäfte der Seehandlungs-Gesellschaft in den ersten Jahren nach ihrer Gründung nicht in dem erhofften Maß. Zu Lebzeiten des Königs kam auch kein Handelsvertrag mit Spanien zustande. Bis die Seehandlung durch die Vorteile, die sie aus dem annektierten Polen ziehen konnte, profitierte, dauerte es noch einige Jahre. N2 - In 1772, three matters that were to retain their importance for a long time occupied the Prussian King Frederick the Great. First was the noble republic of Poland. He intended to partition Poland together with Tsarina Catherine II of Russia and Empress Maria Theresa. This happened on August 5 of that year. The land gain resulting from this act of robbery led Frederick II. to economic considerations. Based on and with the help of the annexed territory, he wanted to intensify Prussian trade, first of all the salt trade and this preferably with Spain, a country with which he had been trying to conclude a trade treaty for quite some time. For this purpose, he founded, among others, the Prussian Sea Trading Company (Preußische Seehandlung), which, to assert itself, received various far-reaching privileges. However, the efforts were not quickly successful. Despite all the privileges granted, the business of the “Seehandlungs-Gesellschaft” did not flourish to the extent hoped for in the first years after its foundation. During the king's lifetime, no trade agreement with Spain was concluded either. It took some time before the Seehandlung profited from the advantages it could derive from annexed Poland. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-599859 SN - 978-3-86956-562-0 SP - 9 EP - 24 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Panwitz, Sebastian T1 - Das Humboldt-Mendelssohn-Haus Jägerstraße 22 BT - ein Quellenfund JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Das Haus in der Jägerstraße, welches um 1800 die Nummer 22 erhielt, ist bekannt als das Elternhaus der Brüder Wilhelm und Alexander von Humboldt. Ob Alexander von Humboldt hier oder im elterlichen Schloß geboren wurde, ist unklar, da er selbst im Verlauf seines Lebens zu dieser Frage widersprüchliche Angaben machte. Das Rätsel des Geburtsortes bleibt vorerst weiter ungelöst. Es ist aber eine Akte aus Privatbesitz aufgetaucht, die zur Geschichte des Hauses Jägerstraße 22 zahlreiche bislang unbekannte Dokumente enthält. Sebastian Panwitz stellt einen Abschnitt daraus vor. KW - Berlin KW - Jägerstraße 22 Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-84949 SN - 1617-5239 SN - 2568-3543 VL - XV IS - 29 SP - 131 EP - 136 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Bredekamp, Horst A1 - Usenbinz, Kay ED - Wienfort, Monika T1 - Das Gebäude: Teil des Gendarmenplatzes und Relais der Berliner Museen JF - Die Preußische Seehandlung zwischen Markt, Staat und Kultur : 40 Jahre Stiftung Preußische Seehandlung N2 - Der Beitrag widmet sich der Baugeschichte des Gebäudes der Preußischen Seehandlung bis zu seinem Abriss und dem Neubau in den Jahren 1901–1903, um dann die Veränderungen dieses Bauwerkes bis in die Gegenwart zu verfolgen. In einem zweiten Schritt wird versucht, die Stellung dieser Gebäude im urbanen Kontext zu verorten. Der dritte Teil rekonstruiert an Beispielen, welch markanten Beitrag die Preußische Seehandlung für die Berliner Museen und insbesondere für die im Berliner Schloss lozierte Kunstkammer wie auch für das Museum für Naturkunde geleistet hat, indem seine Großsegler Meteor und Princess Louise von ihren Weltreisen jeweils reich beladen mit naturkundlichen und völkerkundlichen Exponaten zurückkamen, die durch Austausch oder Kauf oder auch als Geschenk erworben worden waren. N2 - The article examines the architectural history of the building of the Preußische Seehandlung up to its demolition and new construction in 1901–1903 and then traces the changes of this building up to the present. In a second step, an attempt is made to locate the position of these buildings within their urban context. The third part reconstructs by examples the distinctive contribution of the Preußische Seehandlung to the Berlin museums and in particular to the Kunstkammer located in the Berlin Palace as well as to the Museum für Naturkunde. Its tall ships Meteor and Princess Louise returned from their world voyages richly laden with natural history and ethnological exhibits, which had been acquired by exchange or purchase, or also as gifts. Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-599884 SN - 978-3-86956-562-0 SP - 81 EP - 102 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Kraft, Tobias A1 - Päßler, Ulrich ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - Das Ganze erfassen BT - dem Alexander-von-Humboldt-Forscher Eberhard Knobloch zum 80. Geburtstag JF - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies N2 - Der Wissenschaftshistoriker Eberhard Knobloch beschäftigt sich seit rund zwanzig Jahren mit Leben und Werk Alexander von Humboldts. Er zeigt, dass Humboldts Wissenschaftstheorie vom Naturbild der pythagoreischen Schule inspiriert war, seine wissenschaftliche Methode hingegen dem Vorbild der Himmelsmechanik Laplaces folgte. Humboldt entwickelte aus diesen Quellen ein auf Zahlenverhältnisse und Mittelwerte gegründetes Erkenntnismodell, das wegweisend für die datenbasierten Bio- und Geowissenschaften wurde. Die wechselseitige Verbundenheit der verschiedenen Naturphänomene visualisierte Humboldt in seinem ‚Tableau physique des Andes‘. In mehreren Aufsätzen entschlüsselte Eberhard Knobloch auf anschauliche Weise diesen komplexen Blick ins Ganze der Natur. N2 - The historian of science Eberhard Knobloch has been studying the life and work of Alexander von Humboldt for over twenty years. He has shown that Humboldt’s theory of science was inspired by the Pythagorean School’s view of nature, while his scientific method followed the example of Laplace’s Celestial Mechanics. From these sources, Humboldt developed an epistemological model centered on numerical ratios and averages that led the way for databased life and earth sciences. Humboldt visualized the interconnectedness of the various natural phenomena in his ‘Tableau physique des Andes’. In several essays, Eberhard Knobloch decoded this complex view into the unity of nature in a comprehensible way. N2 - El historiador de la ciencia Eberhard Knobloch lleva unos veinte años estudiando la vida y la obra de Alexander von Humboldt. Ha demostrado que la teoría de la ciencia de Humboldt se inspiraba en la visión de la naturaleza de la Escuela Pitagórica, mientras que su método científico seguía el ejemplo de la Mecánica Celeste de Laplace. A partir de estas fuentes, Humboldt desarrolló un modelo epistemológico centrado en proporciones y promedios numéricos que abrió el camino a las bio- y geociencias basadas en datos. Humboldt visualizó la interconexión de los diversos fenómenos naturales en su “Tableau physique des Andes”. En varios ensayos, Eberhard Knobloch descifró esta compleja visión de la totalidad de la naturaleza de una forma comprensible. KW - Eberhard Knobloch KW - 80. Geburtstag Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-617753 SN - 2568-3543 SN - 1617-5239 VL - XXIV IS - 47 SP - 15 EP - 27 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Hermanns, Jolanda T1 - Das erweiterte Fachwissen für den schulischen Kontext BT - Anwendung des Konstruktes zur Entwicklung von Aufgaben und Lehrformaten in der Organischen Chemie JF - PSI-Potsdam: Ergebnisbericht zu den Aktivitäten im Rahmen der Qualitätsoffensive Lehrerbildung (2019-2023) (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 3) N2 - Das Konstrukt des erweiterten Fachwissens für den schulischen Kontext, welches in der ersten Förderphase von PSI-Potsdam entwickelt wurde, diente als Grundlage für die Entwicklung von Aufgaben, Lehrformate sowie einem Laborpraktikum im Bereich organischer Chemie. Eine Delphi-Studie wurde zur Validierung der Anwendung des Konstruktes auf die organische Chemie durchgeführt. Alle Aufgaben und Lehrformate wurden in Mixed-Methods-Studien evaluiert. Es zeigte sich, dass die Studierenden sowohl die Aufgaben als auch die Lehrformate und das Praktikum als relevant für ihren späteren Beruf als Chemielehrkräfte bewerteten. N2 - The construct school related content knowledge, that was developed in the first phase of PSI-Potsdam, has been used as theoretical basis for the development of tasks, learning formats and a laboratory internship on organic chemistry. A Delphi study to validate the application of the construct on organic chemistry has been conducted. All tasks and learning formats have been evaluated using mixed methods designs. It has been shown that the students rate the tasks as well as the learning formats and the internship as relevant for their future profession as a chemistry teacher. KW - Organische Chemie KW - Fachwissen KW - Lehramtsstudierende KW - Laborpraktikum KW - organic chemistry KW - subject knowledge KW - preservice teachers KW - laboratory internship Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-617617 SN - 978-3-86956-568-2 SN - 2626-3556 SN - 2626-4722 IS - 3 SP - 193 EP - 203 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Malek, Jennifer A1 - Tinnefeld, Anja ED - Mientus, Lukas ED - Klempin, Christiane ED - Nowak, Anna T1 - Das ePortfolio als Reflexionselement – Potenziale, Herausforderungen und Umsetzung der Portfolioarbeit an der Universität zu Köln JF - Reflexion in der Lehrkräftebildung: Empirisch – Phasenübergreifend – Interdisziplinär (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 4) N2 - Portfolioarbeit ist ein gesetzlich verankerter Bestandteil der Lehramtsausbildung in Nordrhein-Westfalen. Über alle Praxisphasen hinweg führen Lehramtsstudierende ein Portfolio und dokumentieren darin ihren individuellen Professionalisierungsweg und reflektieren ihre Studien- und Berufswahl, ihre schulpraktischen Beobachtungen und Erfahrungen sowie ihre individuelle Kompetenzentwicklung. Der vorliegende Beitrag gibt einen Überblick über die Arbeit mit dem ePortfolio in der Lehrkräftebildung an der Universität zu Köln (UzK). Dabei werden zunächst die Potenziale von Portfolioarbeit aufgeführt und Herausforderungen herausgestellt. Im Anschluss erfolgt eine konkrete Erläuterung der Notwendigkeit einer kohärenten Einbindung des ePortfolios in die Seminararbeit und eine kurze Darstellung der Weiterentwicklung im Rahmen des Verbundprojekts ePort.nrw. KW - Lehrkräftebildung KW - Reflexion KW - ePortfolio KW - Kohärenz über die Praxisphasen KW - Eignungs- und Orientierungspraktikum KW - Begleitseminar Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-631361 SN - 978-3-86956-566-8 SN - 2626-3556 SN - 2626-4722 IS - 4 SP - 199 EP - 205 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Wittkowski, Ariane A1 - Tägener, Judith A1 - Konarski, Michael A1 - Prickett, David James T1 - Das Drei-Felder-Konzept des Selbstlernbereichs am Zessko BT - Schreibberatung, Vortragscoaching und Sprachtutorien JF - Potsdamer Beiträge zur Hochschulforschung N2 - Dieser Beitrag erläutert, wie die im Teilprojekt entstandenen Selbstlernangebote (Schreibberatung, Vortragscoaching, Sprachtutorien) über die Laufzeit des Teilprojekts (weiter-)entwickelt wurden und wie Studierende durch die Einführung von neuen, flexibleren Lernformaten (z. B. Einzelberatungen) unterstützt werden. Zudem wird aufgezeigt, wie sich wissenschaftlichen Hilfskräften die Möglichkeit bietet, sich als Schreibberater/ in, Vortragscoach oder Sprachtutor/in weiterzubilden. Somit wird an der Universität Potsdam nicht nur das Selbstlernen, sondern auch Peer Learning gefördert. KW - Selbstlernen KW - Schreibberatung KW - Vortragscoaching KW - Sprachtutorien KW - Peer-Lernberater/innen KW - Tutor/innen KW - Beratung KW - Workshops Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-492789 SN - 978-3-86956-498-2 SN - 2192-1075 SN - 2192-1083 IS - 6 SP - 143 EP - 172 PB - Universitätsverlag Potsdam CY - Potsdam ER -