TY - JOUR A1 - Khudair, Mohammed A1 - Marcuzzi, Anna A1 - Ng, Kwok A1 - Tempest, Gavin Daniel A1 - Bartoš, František A1 - Peric, Ratko A1 - Maier, Maximilian A1 - Beccia, Flavia A1 - Boccia, Stefania A1 - Brandes, Mirko A1 - Cardon, Greet A1 - Carlin, Angela A1 - Castagna, Carolina A1 - Chaabene, Helmi A1 - Chalkley, Anna A1 - Ciaccioni, Simone A1 - Cieślińska-Świder, Joanna A1 - Čingienė, Vilma A1 - Cortis, Cristina A1 - Corvino, Chiara A1 - de Geus, Eco J. C. A1 - Di Baldassarre, Angela A1 - Di Credico, Andrea A1 - Drid, Patrik A1 - Tarazaga, Rosa Ma Fernández A1 - Gallè, Francesca A1 - Sánchez, Esther Garcia A1 - Gebremariam, Mekdes A1 - Ghinassi, Barbara A1 - Goudas, Marios A1 - Hayes, Grainne A1 - Honorio, Samuel A1 - Izzicupo, Pascal A1 - Jahre, Henriette A1 - Jelsma, Judith A1 - Juric, Petra A1 - Kolovelonis, Athanasios A1 - Kongsvold, Atle A1 - Kouidi, Evangelia A1 - Mansergh, Fiona A1 - Masanovic, Bojan A1 - Mekonnen, Teferi A1 - Mork, Paul Jarle A1 - Murphy, Marie A1 - O'Hara, Kelly A1 - Torun, Ayse Ozbil A1 - Palumbo, Federico A1 - Popovic, Stevo A1 - Prieske, Olaf A1 - Puharic, Zrinka A1 - Ribeiro, José Carlos A1 - Rumbold, Penny Louise Sheena A1 - Sandu, Petru A1 - Soric, Maroje A1 - Stavnsbo, Mette A1 - Syrmpas, Ioannis A1 - van der Ploeg, Hidde P. A1 - Van Hoye, Aurélie A1 - Vilela, Sofia A1 - Woods, Catherine A1 - Wunsch, Kathrin A1 - Caprinica, Laura A1 - MacDonncha, Ciaran A1 - Ling, Fiona Chun Man T1 - DE-PASS Best Evidence Statement (BESt): modifiable determinants of physical activity and sedentary behaviour in children and adolescents aged 5-19 years-a protocol for systematic review and meta-analysis JF - BMJ open N2 - Introduction Physical activity among children and adolescents remains insufficient, despite the substantial efforts made by researchers and policymakers. Identifying and furthering our understanding of potential modifiable determinants of physical activity behaviour (PAB) and sedentary behaviour (SB) is crucial for the development of interventions that promote a shift from SB to PAB. The current protocol details the process through which a series of systematic literature reviews and meta-analyses (MAs) will be conducted to produce a best-evidence statement (BESt) and inform policymakers. The overall aim is to identify modifiable determinants that are associated with changes in PAB and SB in children and adolescents (aged 5-19 years) and to quantify their effect on, or association with, PAB/SB. Methods and analysis A search will be performed in MEDLINE, SportDiscus, Web of Science, PsychINFO and Cochrane Central Register of Controlled Trials. Randomised controlled trials (RCTs) and controlled trials (CTs) that investigate the effect of interventions on PAB/SB and longitudinal studies that investigate the associations between modifiable determinants and PAB/SB at multiple time points will be sought. Risk of bias assessments will be performed using adapted versions of Cochrane's RoB V.2.0 and ROBINS-I tools for RCTs and CTs, respectively, and an adapted version of the National Institute of Health's tool for longitudinal studies. Data will be synthesised narratively and, where possible, MAs will be performed using frequentist and Bayesian statistics. Modifiable determinants will be discussed considering the settings in which they were investigated and the PAB/SB measurement methods used. Ethics and dissemination No ethical approval is needed as no primary data will be collected. The findings will be disseminated in peer-reviewed publications and academic conferences where possible. The BESt will also be shared with policy makers within the DE-PASS consortium in the first instance. Systematic review registration CRD42021282874. KW - public health KW - health policy KW - community child health Y1 - 2022 U6 - https://doi.org/10.1136/bmjopen-2021-059202 SN - 2044-6055 VL - 12 IS - 9 PB - BMJ Publishing Group CY - London ER -