TY - JOUR
A1 - Baumgardt, Iris
T1 - Berufliche Orientierung von Kindern im Grundschulalter
BT - Analyse von ausgewählten Projekten, Unterrichtsmaterialien und Lehrplänen
N2 - Die berufliche Orientierung von Kindern im Grundschulalter ist bislang nur in Ansätzen erforscht. Gleichwohl gibt es berufsorientierende Angebote, die auf verschiedenen Ebenen Grundschulkinder adressieren. Die Untersuchung fokussiert aktuelle Forschungsergebnisse, ausgewählte Initiativen, Kinderbücher, Unterrichtsmaterialien usw. zur beruflichen Orientierung von Kindern. Mit dem Ziel der Entwicklung und Ausdifferenzierung eines facettenreichen beruflichen Selbstkonzeptes von Kindern werden spezifische Forschungs- und Entwicklungspotenziale aufgezeigt.
Y1 - 2022
SN - 978-3-8340-2199-1
SN - 978-3-7639-7188-6
U6 - https://doi.org/10.3278/9783763971886
PB - Schneider Verlag Hohengehren GmbH
CY - Baltmannsweiler
ER -
TY - JOUR
A1 - Taffarello, Denise
A1 - Srinivasan, Raghavan
A1 - Samprogna Mohor, Guilherme
A1 - Bittencourt Guimaraes, Joao Luis
A1 - Calijuri, Maria do Carmo
A1 - Mendiondo, Eduardo Mario
T1 - Modeling freshwater quality scenarios with ecosystem-based adaptation in the headwaters of the Cantareira system, Brazil
JF - Hydrology and earth system sciences : HESS
N2 - Although hydrologic models provide hypothesis testing of complex dynamics occurring at catchments, fresh-water quality modeling is still incipient at many subtropical headwaters. In Brazil, a few modeling studies assess freshwater nutrients, limiting policies on hydrologic ecosystem services. This paper aims to compare freshwater quality scenarios under different land-use and land-cover (LULC) change, one of them related to ecosystem-based adaptation (EbA), in Brazilian headwaters. Using the spatially semi-distributed Soil and Water Assessment Tool (SWAT) model, nitrate, total phosphorous (TP) and sediment were modeled in catchments ranging from 7.2 to 1037 km(2). These head-waters were eligible areas of the Brazilian payment for ecosystem services (PES) projects in the Cantareira water supply system, which had supplied water to 9 million people in the Sao Paulo metropolitan region (SPMR). We considered SWAT modeling of three LULC scenarios: (i) recent past scenario (S1), with historical LULC in 1990; (ii) current land-use scenario (S2), with LULC for the period 2010-2015 with field validation; and (iii) future land-use scenario with PES (S2 + EbA). This latter scenario proposed forest cover restoration through EbA following the river basin plan by 2035. These three LULC scenarios were tested with a selected record of rainfall and evapotranspiration observed in 2006-2014, with the occurrence of extreme droughts. To assess hydrologic services, we proposed the hydrologic service index (HSI), as a new composite metric comparing water pollution levels (WPL) for reference catchments, related to the grey water footprint (greyWF) and water yield. On the one hand, water quality simulations allowed for the regionalization of greyWF at spatial scales under LULC scenarios. According to the critical threshold, HSI identified areas as less or more sustainable catchments. On the other hand, conservation practices simulated through the S2 + EbA scenario envisaged not only additional and viable best management practices (BMP), but also preventive decision-making at the headwaters of water supply systems.
Y1 - 2018
U6 - https://doi.org/10.5194/hess-22-4699-2018
SN - 1027-5606
SN - 1607-7938
VL - 22
IS - 9
SP - 4699
EP - 4723
PB - Copernicus
CY - Göttingen
ER -
TY - JOUR
A1 - Mitic, Kristina
A1 - Grafe, Marianne
A1 - Batsios, Petros
A1 - Meyer, Irene
T1 - Partial Disassembly of the Nuclear Pore Complex Proteins during Semi-Closed Mitosis in Dictyostelium discoideum
JF - Cells
N2 - Dictyostelium cells undergo a semi-closed mitosis, during which the nuclear envelope (NE) persists; however, free diffusion between the cytoplasm and the nucleus takes place. To permit the formation of the mitotic spindle, the nuclear envelope must be permeabilized in order to allow diffusion of tubulin dimers and spindle assembly factors into the nucleus. In Aspergillus, free diffusion of proteins between the cytoplasm and the nucleus is achieved by a partial disassembly of the nuclear pore complexes (NPCs) prior to spindle assembly. In order to determine whether this is also the case in Dictyostelium, we analysed components of the NPC by immunofluorescence microscopy and live cell imaging and studied their behaviour during interphase and mitosis. We observed that the NPCs are absent from the contact area of the nucleoli and that some nucleoporins also localize to the centrosome and the spindle poles. In addition, we could show that, during mitosis, the central FG protein NUP62, two inner ring components and Gle1 depart from the NPCs, while all other tested NUPs remained at the NE. This leads to the conclusion that indeed a partial disassembly of the NPCs takes place, which contributes to permeabilisation of the NE during semi-closed mitosis.
KW - nuclear pore complex
KW - nucleoporins
KW - semi-closed mitosis
KW - centrosome
KW - Dictyostelium
Y1 - 2021
U6 - https://doi.org/10.3390/cells11030407
SN - 2073-4409
VL - 11
IS - 3
PB - MDPI
CY - Basel
ER -
TY - JOUR
A1 - Mattis, Toni
A1 - Beckmann, Tom
A1 - Rein, Patrick
A1 - Hirschfeld, Robert
T1 - First-class concepts
BT - Reified architectural knowledge beyond dominant decompositions
JF - Journal of object technology : JOT / ETH Zürich, Department of Computer Science
N2 - Ideally, programs are partitioned into independently maintainable and understandable modules. As a system grows, its architecture gradually loses the capability to accommodate new concepts in a modular way. While refactoring is expensive and not always possible, and the programming language might lack dedicated primary language constructs to express certain cross-cutting concerns, programmers are still able to explain and delineate convoluted concepts through secondary means: code comments, use of whitespace and arrangement of code, documentation, or communicating tacit knowledge.
Secondary constructs are easy to change and provide high flexibility in communicating cross-cutting concerns and other concepts among programmers. However, such secondary constructs usually have no reified representation that can be explored and manipulated as first-class entities through the programming environment.
In this exploratory work, we discuss novel ways to express a wide range of concepts, including cross-cutting concerns, patterns, and lifecycle artifacts independently of the dominant decomposition imposed by an existing architecture. We propose the representation of concepts as first-class objects inside the programming environment that retain the capability to change as easily as code comments. We explore new tools that allow programmers to view, navigate, and change programs based on conceptual perspectives. In a small case study, we demonstrate how such views can be created and how the programming experience changes from draining programmers' attention by stretching it across multiple modules toward focusing it on cohesively presented concepts. Our designs are geared toward facilitating multiple secondary perspectives on a system to co-exist in symbiosis with the original architecture, hence making it easier to explore, understand, and explain complex contexts and narratives that are hard or impossible to express using primary modularity constructs.
KW - software engineering
KW - modularity
KW - exploratory programming
KW - program
KW - comprehension
KW - remodularization
KW - architecture recovery
Y1 - 2022
U6 - https://doi.org/10.5381/jot.2022.21.2.a6
SN - 1660-1769
VL - 21
IS - 2
SP - 1
EP - 15
PB - ETH Zürich, Department of Computer Science
CY - Zürich
ER -
TY - JOUR
A1 - Marcisz, Katarzyna
A1 - Jassey, Vincent E. J.
A1 - Kosakyan, Anush
A1 - Krashevska, Valentyna
A1 - Lahr, Daniel J. G.
A1 - Lara, Enrique
A1 - Lamentowicz, Lukasz
A1 - Lamentowicz, Mariusz
A1 - Macumber, Andrew
A1 - Mazei, Yuri
A1 - Mitchell, Edward A. D.
A1 - Nasser, Nawaf A.
A1 - Patterson, R. Timothy
A1 - Roe, Helen M.
A1 - Singer, David
A1 - Tsyganov, Andrey N.
A1 - Fournier, Bertrand
T1 - Testate amoeba functional traits and their use in paleoecology
JF - Frontiers in Ecology and Evolution
N2 - This review provides a synthesis of current knowledge on the morphological and functional traits of testate amoebae, a polyphyletic group of protists commonly used as proxies of past hydrological changes in paleoecological investigations from peatland, lake sediment and soil archives. A trait-based approach to understanding testate amoebae ecology and paleoecology has gained in popularity in recent years, with research showing that morphological characteristics provide complementary information to the commonly used environmental inferences based on testate amoeba (morpho-)species data. We provide a broad overview of testate amoeba morphological and functional traits and trait-environment relationships in the context of ecology, evolution, genetics, biogeography, and paleoecology. As examples we report upon previous ecological and paleoecological studies that used trait-based approaches, and describe key testate amoebae traits that can be used to improve the interpretation of environmental studies. We also highlight knowledge gaps and speculate on potential future directions for the application of trait-based approaches in testate amoeba research.
KW - protists
KW - functional traits
KW - morphological traits
KW - ecology
KW - peatlands
KW - lakes
KW - soils
KW - trait-based approaches
Y1 - 2020
U6 - https://doi.org/10.3389/fevo.2020.575966
SN - 2296-701X
VL - 8
PB - Frontiers Media
CY - Lausanne
ER -
TY - JOUR
A1 - Grafe, Marianne
A1 - Hofmann, Phillip
A1 - Batsios, Petros
A1 - Meyer, Irene
A1 - Gräf, Ralph
T1 - In vivo assembly of a Dictyostelium lamin mutant induced by light, mechanical stress, and pH
JF - Cells : open access journal
N2 - We expressedDictyosteliumlamin (NE81) lacking both a functional nuclear localization signal and a CAAX-box for C-terminal lipid modification. This lamin mutant assembled into supramolecular, three-dimensional clusters in the cytosol that disassembled at the onset of mitosis and re-assembled in late telophase, thus mimicking the behavior of the endogenous protein. As disassembly is regulated by CDK1-mediated phosphorylation at serine 122, we generated a phosphomimetic S122E mutant called GFP-NE81-S122E-Delta NLS Delta CLIM. Surprisingly, during imaging, the fusion protein assembled into cytosolic clusters, similar to the protein lacking the phosphomimetic mutation. Clusters disassembled again in the darkness. Assembly could be induced with blue but not green or near ultraviolet light, and it was independent of the fusion tag. Assembly similarly occurred upon cell flattening. Earlier reports and own observations suggested that both blue light and cell flattening could result in a decrease of intracellular pH. Indeed, keeping the cells at low pH also reversibly induced cluster formation. Our results indicate that lamin assembly can be induced by various stress factors and that these are transduced via intracellular acidification. Although these effects have been shown in a phosphomimetic CDK1 mutant of theDictyosteliumlamin, they are likely relevant also for wild-type lamin.
KW - lamin
KW - NE81
KW - Dictyostelium
KW - nuclear envelope
KW - nuclear lamina
Y1 - 2020
U6 - https://doi.org/10.3390/cells9081834
SN - 2073-4409
VL - 9
IS - 8
PB - MDPI
CY - Basel
ER -
TY - JOUR
A1 - Neumann, Bettina
A1 - Wollenberger, Ulla
T1 - Electrochemical biosensors employing natural and artificial heme peroxidases on semiconductors
JF - Sensors
N2 - Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focuses on approaches for the construction of electrochemical biosensors employing natural heme peroxidases as well as various mimics immobilized on semiconducting electrode surfaces. It will outline important advances made so far as well as the novel applications resulting thereof.
KW - electrochemical biosensors
KW - heme
KW - peroxidases
KW - semiconductors
KW - peroxidase mimics
Y1 - 2020
U6 - https://doi.org/10.3390/s20133692
SN - 1424-8220
VL - 20
IS - 13
PB - MDPI
CY - Basel
ER -
TY - JOUR
A1 - Rose, Robert
A1 - Groeger, Lars
A1 - Hölzle, Katharina
T1 - The Emergence of Shared Leadership in Innovation Labs
JF - Frontiers in Psychology
N2 - Implementing innovation laboratories to leverage intrapreneurship are an increasingly popular organizational practice. A typical feature in these creative environments are semi-autonomous teams in which multiple members collectively exert leadership influence, thereby challenging traditional command-and-control conceptions of leadership. An extensive body of research on the team-centric concept of shared leadership has recognized the potential for pluralized leadership structures in enhancing team effectiveness; however, little empirical work has been conducted in organizational contexts in which creativity is key. This study set out to explore antecedents of shared leadership and its influence on team creativity in an innovation lab. Building on extant shared leadership and innovation research, we propose antecedents customary to creative teamwork, that is, experimental culture, task reflexivity, and voice. Multisource data were collected from 104 team members and 49 evaluations of 29 coaches nested in 21 teams working in a prototypical innovation lab. We identify factors specific to creative teamwork that facilitate the emergence of shared leadership by providing room for experimentation, encouraging team members to speak up in the creative process, and cultivating a reflective application of entrepreneurial thinking. We provide specific exemplary activities for innovation lab teams to increase levels of shared leadership.
KW - innovation laboratories
KW - intrapreneurship
KW - team creativity
KW - shared leadership
KW - social network analysis
Y1 - 2021
U6 - https://doi.org/10.3389/fpsyg.2021.685167
SN - 1664-1078
VL - 12
SP - 1
EP - 13
PB - Frontiers in psychology
CY - Lausanne, Schweiz
ER -
TY - JOUR
A1 - Streck, Charlotte
T1 - Who owns REDD+?
BT - carbon markets, carbon rights and entitlements to REDD+ finance
JF - Forests
N2 - The question of who is entitled to benefit from transactions under the United Nations framework to reduce emissions from deforestation and forest degradation (REDD+) remains one of the most controversial issues surrounding cooperative efforts to reduce deforestation in developing countries. REDD+ has been conceived as an international framework to encourage voluntary efforts in developing countries to reduce greenhouse gas emissions and enhance carbon removals from forest activities. It was designed as an international framework under the United Nations Framework Convention on Climate Change (UNFCCC) to enable the generation of emission reductions and removals (ERRs) at the national-and, provisionally, the subnational-level and is, thus, primarily a creature of international law. However, in defining forest carbon ERRs, the international framework competes with national emission trading systems and domestic REDD+ legislation as well as private standards that define units traded on the voluntary carbon market. As results-based and carbon market systems emerge, the question remains: Who can claim participation in REDD+ and voluntary carbon market projects? The existence of different international, national and private standards that value ERRs poses a challenge to countries that participate in REDD+ as well as to communities and private actors participating in voluntary carbon market projects. This paper seeks to clarify the nature and limitation of rights pertaining to REDD+ market transactions. It also links the notion of carbon rights to both carbon markets and government's decision on benefit sharing. Applying a legal lens, this paper helps to understand the various claims and underlying rights to participate in REDD+ transactions and addresses ambiguities that can lead to conflict around REDD+ implementation. The definition of carbon rights and the legal nature of carbon credits depend on local law and differ between countries. However, by categorizing carbon rights, the paper summarizes several legal considerations that are relevant for regulating REDD+ and sharing the financial benefits of transacting ERRs.
KW - REDD plus
KW - REDD+
KW - avoided deforestation
KW - voluntary carbon markets
KW - emissions
KW - trading
KW - carbon rights
KW - benefit sharing
Y1 - 2020
U6 - https://doi.org/10.3390/f11090959
SN - 1999-4907
VL - 11
IS - 9
PB - MDPI
CY - Basel
ER -
TY - JOUR
A1 - Dordevic, Milos
A1 - Hölzer, Sonja
A1 - Russo, Augusta
A1 - García Alanis, José Carlos
A1 - Müller, Notger Germar
T1 - The Role of the Precuneus in Human Spatial Updating in a Real Environment Setting—A cTBS Study
JF - Life
N2 - As we move through an environment, we update positions of our body relative to other objects, even when some objects temporarily or permanently leave our field of view—this ability is termed egocentric spatial updating and plays an important role in everyday life. Still, our knowledge about its representation in the brain is still scarce, with previous studies using virtual movements in virtual environments or patients with brain lesions suggesting that the precuneus might play an important role. However, whether this assumption is also true when healthy humans move in real environments where full body-based cues are available in addition to the visual cues typically used in many VR studies is unclear. Therefore, in this study we investigated the role of the precuneus in egocentric spatial updating in a real environment setting in 20 healthy young participants who underwent two conditions in a cross-over design: (a) stimulation, achieved through applying continuous theta-burst stimulation (cTBS) to inhibit the precuneus and (b) sham condition (activated coil turned upside down). In both conditions, participants had to walk back with blindfolded eyes to objects they had previously memorized while walking with open eyes. Simplified trials (without spatial updating) were used as control condition, to make sure the participants were not affected by factors such as walking blindfolded, vestibular or working memory deficits. A significant interaction was found, with participants performing better in the sham condition compared to real stimulation, showing smaller errors both in distance and angle. The results of our study reveal evidence of an important role of the precuneus in a real-environment egocentric spatial updating; studies on larger samples are necessary to confirm and further investigate this finding.
KW - precuneus
KW - spatial updating
KW - TMS
KW - cTBS
Y1 - 2022
U6 - https://doi.org/10.3390/life12081239
SN - 2075-1729
VL - 12
SP - 1
EP - 13
PB - MDPI
CY - Basel, Schweiz
ET - 8
ER -