TY  - GEN
A1  - Püschel, Gerhard Paul
A1  - Nath, Annegret
A1  - Jungermann, Kurt
T1  - Increase of urate formation by stimulation of sympathetic hepatic nerves, circulating noradrenaline and glucagon inthe perfused rat liver
N2  - In the isolated rat liver perfused in situ stimulation of the nerve bundles around the portal vein and the hepatic artery caused an increase of urate formation that was inhibited by the α1-blocker prazosine and the xanthine oxidase inhibitor allopurinol. Moreover, nerve stimulation increased glucose and lactate output and decreased perfusion flow. Infusion of noradrenaline had similar effects. Compared to nerve stimulation infusion of glucagon led to a less pronounced increase of urate formation and a twice as large increase in glucose output but a decrease in lactate release without affecting the flow rate. Insulin had no effect on any of the parameters studied.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 038 
KW  - Urate
KW  - Allantoin
KW  - Hepatic nerve
KW  - Catecholamine
KW  - Glucagon
Y1  - 1987
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16728
ER  - 
TY  - GEN
A1  - Werner, John S.
A1  - Donnelly, Seaneen K.
A1  - Kliegl, Reinhold
T1  - Aging and human macular pigment density : appended with translations from the work of Max Schultze and Ewald Hering
N2  - The optical density of human macular pigment was measured for 50 observers ranging in age from 10 to 90 years. The psychophysical method required adjusting the radiance of a 1°, monochromatic light (400–550 nm) to minimize flicker (15 Hz) when presented in counterphase with a 460 nm standard. This test stimulus was presented superimposed on a broad-band, short-wave background. Macular pigment density was determined by comparing sensitivity under these conditions for the fovea, where macular pigment is maximal, and 5° temporally. This difference spectrum, measured for 12 observers, matched Wyszecki and Stiles's standard density spectrum for macular pigment. To study variation in macular pigment density for a larger group of observers, measurements were made at only selected spectral points (460, 500 and 550 nm). The mean optical density at 460 nm for the complete sample of 50 subjects was 0.39. Substantial individual differences in density were found (ca. 0.10–0.80), but this variation was not systematically related to age.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - paper 037 
KW  - Macular pigment
KW  - Color vision Aging
Y1  - 1987
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16836
ER  -