TY  - JOUR
A1  - Ogunkola, Moses Olalekan
A1  - Guiraudie-Capraz, Gaelle
A1  - Féron, François
A1  - Leimkühler, Silke
T1  - The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells
JF  - Biomolecules
N2  - Sulfur is an important element that is incorporated into many biomolecules in humans. The incorporation and transfer of sulfur into biomolecules is, however, facilitated by a series of different sulfurtransferases. Among these sulfurtransferases is the human mercaptopyruvate sulfurtransferase (MPST) also designated as tRNA thiouridine modification protein (TUM1). The role of the human TUM1 protein has been suggested in a wide range of physiological processes in the cell among which are but not limited to involvement in Molybdenum cofactor (Moco) biosynthesis, cytosolic tRNA thiolation and generation of H2S as signaling molecule both in mitochondria and the cytosol. Previous interaction studies showed that TUM1 interacts with the L-cysteine desulfurase NFS1 and the Molybdenum cofactor biosynthesis protein 3 (MOCS3). Here, we show the roles of TUM1 in human cells using CRISPR/Cas9 genetically modified Human Embryonic Kidney cells. Here, we show that TUM1 is involved in the sulfur transfer for Molybdenum cofactor synthesis and tRNA thiomodification by spectrophotometric measurement of the activity of sulfite oxidase and liquid chromatography quantification of the level of sulfur-modified tRNA. Further, we show that TUM1 has a role in hydrogen sulfide production and cellular bioenergetics.
KW  - Moco biosynthesis
KW  - sulfite oxidase
KW  - cytosolic tRNA thiolation
KW  - 5-methoxycarbonylmethyl-2-thiouridine
KW  - H2S biosynthesis
KW  - cellular bioenergetics
Y1  - 2023
U6  - https://doi.org/10.3390/biom13010144
SN  - 2218-273X
VL  - 13
SP  - 1
EP  - 23
PB  - MDPI
CY  - Basel, Schweiz
ET  - 1
ER  - 
TY  - JOUR
A1  - Marggraf, Lara Christin
A1  - Lindecke, Oliver
A1  - Voigt, Christian C.
A1  - Pētersons, Gunārs
A1  - Voigt-Heucke, Silke Luise
T1  - Nathusius’ bats, Pipistrellus nathusii, bypass mating opportunities of their own species, but respond to foraging heterospecifics on migratory transit flights
JF  - Frontiers in Ecology and Evolution
N2  - In late summer, migratory bats of the temperate zone face the challenge of accomplishing two energy-demanding tasks almost at the same time: migration and mating. Both require information and involve search efforts, such as localizing prey or finding potential mates. In non-migrating bat species, playback studies showed that listening to vocalizations of other bats, both con-and heterospecifics, may help a recipient bat to find foraging patches and mating sites. However, we are still unaware of the degree to which migrating bats depend on con-or heterospecific vocalizations for identifying potential feeding or mating opportunities during nightly transit flights. Here, we investigated the vocal responses of Nathusius’ pipistrelle bats, Pipistrellus nathusii, to simulated feeding and courtship aggregations at a coastal migration corridor. We presented migrating bats either feeding buzzes or courtship calls of their own or a heterospecific migratory species, the common noctule, Nyctalus noctula. We expected that during migratory transit flights, simulated feeding opportunities would be particularly attractive to bats, as well as simulated mating opportunities which may indicate suitable roosts for a stopover. However, we found that when compared to the natural silence of both pre-and post-playback phases, bats called indifferently during the playback of conspecific feeding sounds, whereas P. nathusii echolocation call activity increased during simulated feeding of N. noctula. In contrast, the call activity of P. nathusii decreased during the playback of conspecific courtship calls, while no response could be detected when heterospecific call types were broadcasted. Our results suggest that while on migratory transits, P. nathusii circumnavigate conspecific mating aggregations, possibly to save time or to reduce the risks associated with social interactions where aggression due to territoriality might be expected. This avoidance behavior could be a result of optimization strategies by P. nathusii when performing long-distance migratory flights, and it could also explain the lack of a response to simulated conspecific feeding. However, the observed increase of activity in response to simulated feeding of N. noctula, suggests that P. nathusii individuals may be eavesdropping on other aerial hawking insectivorous species during migration, especially if these occupy a slightly different foraging niche.
KW  - playback
KW  - phonotaxis
KW  - bats
KW  - acoustic communication
KW  - animal migration
KW  - eavesdropping
KW  - echolocation
KW  - Pipistrellus nathusii
Y1  - 2023
U6  - https://doi.org/10.3389/fevo.2022.908560
SN  - 2296-701X
SP  - 1
EP  - 10
PB  - Frontiers
CY  - Lausanne, Schweiz
ER  - 
TY  - JOUR
A1  - Ullrich, Rebecca
A1  - Abramowicz, Isidoro
T1  - Ein unbekannter Piyyut für Schabbat aus Reckendorf
JF  - Genisa-Blätter IV
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-584897
SN  - 978-3-86956-539-2
SP  - 73
EP  - 82
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Smith, Taylor
A1  - Zotta, Ruxandra-Maria
A1  - Boulton, Chris A.
A1  - Lenton, Timothy M.
A1  - Dorigo, Wouter
A1  - Boers, Niklas
T1  - Reliability of resilience estimation based on multi-instrument time series
JF  - Earth System Dynamics
N2  - Many widely used observational data sets are comprised of several overlapping instrument records. While data inter-calibration techniques often yield continuous and reliable data for trend analysis, less attention is generally paid to maintaining higher-order statistics such as variance and autocorrelation. A growing body of work uses these metrics to quantify the stability or resilience of a system under study and potentially to anticipate an approaching critical transition in the system. Exploring the degree to which changes in resilience indicators such as the variance or autocorrelation can be attributed to non-stationary characteristics of the measurement process – rather than actual changes in the dynamical properties of the system – is important in this context. In this work we use both synthetic and empirical data to explore how changes in the noise structure of a data set are propagated into the commonly used resilience metrics lag-one autocorrelation and variance. We focus on examples from remotely sensed vegetation indicators such as vegetation optical depth and the normalized difference vegetation index from different satellite sources. We find that time series resulting from mixing signals from sensors with varied uncertainties and covering overlapping time spans can lead to biases in inferred resilience changes. These biases are typically more pronounced when resilience metrics are aggregated (for example, by land-cover type or region), whereas estimates for individual time series remain reliable at reasonable sensor signal-to-noise ratios. Our work provides guidelines for the treatment and aggregation of multi-instrument data in studies of critical transitions and resilience.
Y1  - 2023
U6  - https://doi.org/10.5194/esd-14-173-2023
SN  - 2190-4987
VL  - 14
SP  - 173
EP  - 183
PB  - Copernicus Publications
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Felsing, Ulrike
T1  - Elternpartizipation: Hand in Hand – wie die Kommunikation zwischen Therapeut:innen und Eltern gelingt
JF  - Spektrum Patholinguistik 16
N2  - Für eine gelingende Kommunikation und Zusammenarbeit zwischen Therapeut:innen und Eltern sind meines Erachtens zwei Aspekte wesentlich: die therapeutische Haltung/innere Einstellung zur Beziehungsgestaltung auf Seiten der Therapeut:innen sowie ihr Wissen und die Fähigkeiten, Eltern ganz pragmatisch in den therapeutischen Prozess einzubinden.
KW  - Elternpartizipation
KW  - Beziehungsgestaltung
KW  - Kommunikation
KW  - Sprachtherapie
KW  - Kindertherapie
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-613395
SN  - 978-3-86956-559-0
SN  - 1866-9433
SN  - 1869-3822
IS  - 16
SP  - 1
EP  - 14
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Singer-Brehm, Elisabeth
T1  - ‚Maise Jeschurun‘
BT  - Die Geschichte einer Ritualmordanklage
JF  - Genisa-Blätter IV
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-584932
SN  - 978-3-86956-539-2
SP  - 129
EP  - 157
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Uličná, Lenka
T1  - Zur Unheil abwendenden Funktion der Genisa
JF  - Genisa-Blätter IV
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-584868
SN  - 978-3-86956-539-2
SP  - 27
EP  - 39
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Cohen-Hattab, Kobi
T1  - Pioneers of Independent Jewish Shipping
BT  - The Emergence of Private Jewish Shipping Companies in Palestine, 1934 – 1939
JF  - PaRDeS : Journal of the Association for Jewish Studies in Germany
JF  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V.
N2  - The birth of the Yishuv’s national shipping company, ZIM was preceded by private enterprise; the sea had not traditionally been a focus of the Zionist movement. In the 1930s, a five-year span of private commercial shipping saw three companies in the Jewish community in Palestine – Palestine Shipping Company, Palestine Maritime Lloyd, and Atid – before shipping was cut short by the outbreak of the Second World War. Despite their brief lifespans and their negligible contribution to general shipping, these companies constituted an important milestone. Their existence helped shift the Yishuv leadership’s attitudes about shipping’s importance for the community and the need for it to be supported by national institutions.
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-585542
SN  - 978-3-86956-552-1
SN  - 1614-6492
SN  - 1862-7684
IS  - 28
SP  - 34
EP  - 50
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Weinmann, Franziska
T1  - Mothers of Seafaring
BT  - Henrietta Diamond and the Question of Female Representation in the Jewish Maritime Realm
JF  - PaRDeS : Journal of the Association for Jewish Studies in Germany
JF  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V.
N2  - The article aims to trace the contribution of Jewish women in the Yishuv’s maritime history. Taking the example of Henrietta Diamond, a founding member and chairperson of the Zebulun Seafaring Society, the article seeks to explore the representation and role of women in a growing Jewish maritime domain from the 1930s to the 1950s. It examines Zionist narratives on the ‘New Jew’ and the Jewish body and studies their relevance for the emerging field of maritime activities in the Yishuv. By contextualizing the work and depiction of Henrietta Diamond, the article sheds new light on the gendered notions that underlay the emergence of the Jewish maritime domain and illustrates the patterns of inclusion and exclusion in it.
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-585563
SN  - 978-3-86956-552-1
SN  - 1614-6492
SN  - 1862-7684
IS  - 28
SP  - 52
EP  - 67
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Ghassemi, Novid
A1  - Opitz, Ben
A1  - Brämer, Martin
A1  - Gasparjan, David
A1  - Sambanis, Michaela
A1  - Köster, Hilde
A1  - Lücke, Martin
A1  - Nordmeier, Volkhard
ED  - Mientus, Lukas
ED  - Klempin, Christiane
ED  - Nowak, Anna
T1  - Das „Lehr-Lern-Labor“ als Lehrkonzept zur Förderung einer reflexiven Haltung bei Lehramtsstudent:nnen unterschiedlicher Fächer
JF  - Reflexion in der Lehrkräftebildung: Empirisch – Phasenübergreifend – Interdisziplinär (Potsdamer Beiträge zur Lehrerbildung und Bildungsforschung ; 4)
N2  - Eine reflexive Haltung gegenüber der eigenen Lehrtätigkeit gilt als Schlüsselqualifikation in Bezug auf die Professionalisierung von Lehrer:innen in allen Didaktiken (GFD, 2004, S. 4). Das universitäre Seminarformat Lehr-Lern-Labor (LLLS) kann diese Haltung fördern (Rehfeldt et al., 2018). Das Lehrformat eignet sich außerdem zur Steigerung des Professionswissens und der unterrichtlichen Handlungsfähigkeit angehender Lehrer:innen (Rehfeldt et al., 2020; Brämer & Köster, 2021). Dieser Beitrag stellt, neben der grundsätzlichen Konzeption des Seminarformats, dessen Implementierung in vier verschiedenen Fachdidaktiken (Didaktiken des Englischen, der Geschichte, der Physik und Sachunterricht und seine Didaktik) vor. Ein Fokus liegt dabei auf der unterschiedlichen Umsetzung der Reflexionsphasen.
KW  - Lehr-Lern-Labor-Seminar
KW  - Physik
KW  - Englisch
KW  - Geschichte
KW  - Sachunterricht
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-631924
SN  - 978-3-86956-566-8
SN  - 2626-3556
SN  - 2626-4722
IS  - 4
SP  - 389
EP  - 396
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  -