TY - JOUR A1 - Bordihn, Henning A1 - Mitrana, Victor A1 - Paun, Andrei A1 - Paun, Mihaela T1 - Hairpin completions and reductions BT - semilinearity properties JF - Natural computing : an innovative journal bridging biosciences and computer sciences ; an international journal N2 - This paper is part of the investigation of some operations on words and languages with motivations coming from DNA biochemistry, namely three variants of hairpin completion and three variants of hairpin reduction. Since not all the hairpin completions or reductions of semilinear languages remain semilinear, we study sufficient conditions for semilinear languages to preserve their semilinearity property after applying the non-iterated hairpin completion or hairpin reduction. A similar approach is then applied to the iterated variants of these operations. Along these lines, we define the hairpin reduction root of a language and show that the hairpin reduction root of a semilinear language is not necessarily semilinear except the universal language. A few open problems are finally discussed. KW - DNA hairpin formation KW - Hairpin completions KW - Hairpin reductions KW - Semilinearity property Y1 - 2020 U6 - https://doi.org/10.1007/s11047-020-09797-0 SN - 1572-9796 VL - 20 IS - 2 SP - 193 EP - 203 PB - Springer Science + Business Media B.V. CY - Dordrecht ER - TY - JOUR A1 - Schneider, Jan Niklas A1 - Brick, Timothy R. A1 - Dziobek, Isabel T1 - Distance to the neutral face predicts arousal ratings of dynamic facial expressions in individuals with and without Autism Spectrum Disorder JF - Frontiers in psychology N2 - Arousal is one of the dimensions of core affect and frequently used to describe experienced or observed emotional states. While arousal ratings of facial expressions are collected in many studies it is not well understood how arousal is displayed in or interpreted from facial expressions. In the context of socioemotional disorders such as Autism Spectrum Disorder, this poses the question of a differential use of facial information for arousal perception. In this study, we demonstrate how automated face-tracking tools can be used to extract predictors of arousal judgments. We find moderate to strong correlations among all measures of static information on one hand and all measures of dynamic information on the other. Based on these results, we tested two measures, average distance to the neutral face and average facial movement speed, within and between neurotypical individuals (N = 401) and individuals with autism (N = 19). Distance to the neutral face was predictive of arousal in both groups. Lower mean arousal ratings were found for the autistic group, but no difference in correlation of the measures and arousal ratings could be found between groups. Results were replicated in an high autistic traits group. The findings suggest a qualitatively similar perception of arousal for individuals with and without autism. No correlations between valence ratings and any of the measures could be found, emphasizing the specificity of our tested measures. Distance and speed predictors share variability and thus speed should not be discarded as a predictor of arousal ratings. KW - arousal KW - face tracking KW - facial expression KW - autism KW - perception KW - perception differences KW - measure development Y1 - 2020 U6 - https://doi.org/10.3389/fpsyg.2020.577494 SN - 1664-1078 VL - 11 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Luther, Laura A1 - Tiberius, Victor A1 - Brem, Alexander T1 - User experience (UX) in business, management, and psychology BT - a bibliometric mapping of the current state of research JF - Multimodal technologies and interaction : open access journal N2 - User Experience (UX) describes the holistic experience of a user before, during, and after interaction with a platform, product, or service. UX adds value and attraction to their sole functionality and is therefore highly relevant for firms. The increased interest in UX has produced a vast amount of scholarly research since 1983. The research field is, therefore, complex and scattered. Conducting a bibliometric analysis, we aim at structuring the field quantitatively and rather abstractly. We employed citation analyses, co-citation analyses, and content analyses to evaluate productivity and impact of extant research. We suggest that future research should focus more on business and management related topics. KW - bibliometric analysis KW - co-citation analysis KW - co-occurrence analysis KW - citation analysis KW - user experience KW - UX Y1 - 2020 U6 - https://doi.org/10.3390/mti4020018 SN - 2414-4088 VL - 4 IS - 2 PB - MDPI CY - Basel ER - TY - JOUR A1 - Lucke, Ulrike A1 - Hafer, Jörg A1 - Hartmann, Niklas T1 - Strategieentwicklung in der Hochschule als partizipativer Prozess BT - Beispiele und Erkenntnisse JF - Potsdamer Beiträge zur Hochschulforschung N2 - Die Setzung strategischer Ziele sowie die Zuordnung und Umsetzung dazugehörender Maßnahmen sind ein wesentliches Element, um die Innovationsfähigkeit von Organisationen zu erhalten. In den vergangenen Jahren ist auch an Hochschulen die Strategiebildung deutlich vorangetrieben worden. Dies betrifft verschiedene Handlungsfelder, und es werden verschiedene Ansätze verfolgt. Der vorliegende Beitrag greift am Beispiel der Universität Potsdam drei in den vergangenen Jahren adressierte Strategiebereiche heraus: IT, E-Learning und Forschungsdaten. Die damit verbundenen Prozesse waren in unterschiedlichem Maß von Partizipation geprägt. Die gesammelten Erfahrungen werden reflektiert, und es werden Empfehlungen für Strategieentwicklungsprozesse abgeleitet. KW - Innovation KW - Strategie KW - Partizipation KW - IT-Infrastruktur KW - E-Learning KW - Forschungsdatenmanagement Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-492764 SN - 978-3-86956-498-2 SN - 2192-1075 SN - 2192-1083 IS - 6 SP - 99 EP - 117 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Hempel, Sabrina A1 - Adolphs, Julian A1 - Landwehr, Niels A1 - Willink, Dilya A1 - Janke, David A1 - Amon, Thomas T1 - Supervised machine learning to assess methane emissions of a dairy building with natural ventilation JF - Applied Sciences N2 - A reliable quantification of greenhouse gas emissions is a basis for the development of adequate mitigation measures. Protocols for emission measurements and data analysis approaches to extrapolate to accurate annual emission values are a substantial prerequisite in this context. We systematically analyzed the benefit of supervised machine learning methods to project methane emissions from a naturally ventilated cattle building with a concrete solid floor and manure scraper located in Northern Germany. We took into account approximately 40 weeks of hourly emission measurements and compared model predictions using eight regression approaches, 27 different sampling scenarios and four measures of model accuracy. Data normalization was applied based on median and quartile range. A correlation analysis was performed to evaluate the influence of individual features. This indicated only a very weak linear relation between the methane emission and features that are typically used to predict methane emission values of naturally ventilated barns. It further highlighted the added value of including day-time and squared ambient temperature as features. The error of the predicted emission values was in general below 10%. The results from Gaussian processes, ordinary multilinear regression and neural networks were least robust. More robust results were obtained with multilinear regression with regularization, support vector machines and particularly the ensemble methods gradient boosting and random forest. The latter had the added value to be rather insensitive against the normalization procedure. In the case of multilinear regression, also the removal of not significantly linearly related variables (i.e., keeping only the day-time component) led to robust modeling results. We concluded that measurement protocols with 7 days and six measurement periods can be considered sufficient to model methane emissions from the dairy barn with solid floor with manure scraper, particularly when periods are distributed over the year with a preference for transition periods. Features should be normalized according to median and quartile range and must be carefully selected depending on the modeling approach. KW - greenhouse gas KW - on-farm evaluation KW - emission factor KW - regression KW - ensemble methods KW - gradient boosting KW - random forest KW - neural networks KW - support vector machines Y1 - 2020 U6 - https://doi.org/10.3390/app10196938 SN - 2076-3417 VL - 10 IS - 19 PB - MDPI CY - Basel ER - TY - JOUR A1 - Strickroth, Sven A1 - Kiy, Alexander T1 - E-Assessment etablieren BT - Auf dem Weg zu (dezentralen) E-Klausuren JF - Potsdamer Beiträge zur Hochschulforschung N2 - Elektronische Lernstandserhebungen, sogenannte E-Assessments, bieten für Lehrende und Studierende viele Vorteile z. B. hinsichtlich schneller Rückmeldungen oder kompetenzorientierter Fragenformate, und ermöglichen es, unabhängig von Ort und Zeit Prüfungen zu absolvieren. In diesem Beitrag werden die Einführung von summativen Lernstandserhebungen, sogenannter E-Klausuren, am Beispiel der Universität Potsdam, der Aufbau einer länderübergreifenden Initiative für E-Assessment sowie technische Möglichkeiten für dezentrale elektronische Klausuren vorgestellt. Dabei werden der aktuelle Stand, die Ziele und die gewählte stufenweise Umsetzungsstrategie der Universität Potsdam skizziert. Darauf aufbauend folgt eine Beschreibung des Vorgehens, der Kooperationsmöglichkeiten für den Wissens- und Erfahrungsaustausch sowie Herausforderungen der E-Assessment- Initiative. Abschließend werden verschiedene E-Klausurformen und technische Möglichkeiten zur Umsetzung komplexer Prüfungsumgebungen klassifiziert sowie mit ihren charakteristischen Vor- und Nachteilen diskutiert und eine integrierte Lösung vorgeschlagen. KW - E-Assessment KW - Elektronisches Prüfen KW - E-Klausuren KW - Digitalisierung Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-493036 SN - 978-3-86956-498-2 SN - 2192-1075 SN - 2192-1083 IS - 6 SP - 257 EP - 272 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Lucke, Ulrike A1 - Strickroth, Sven T1 - Digitalisierung in Lehre und Studium BT - Eine hochschulweite Perspektive JF - Potsdamer Beiträge zur Hochschulforschung N2 - Das größte der fächerübergreifenden Projekte im Potsdamer Projekt Qualitätspakt Lehre hatte die flächendeckende Etablierung von digitalen Medien als einen integralen Bestandteil von Lehre und Studium zum Gegenstand. Im Teilprojekt E-Learning in Studienbereichen (eLiS) wurden dafür Maßnahmen in den Feldern Organisations-, technische und Inhaltsentwicklung zusammengeführt. Der vorliegende Beitrag präsentiert auf Basis von Ausgangslage und Zielsetzungen die Ergebnisse rund um die Digitalisierung von Lehre und Studium an der Universität Potsdam. Exemplarisch werden fünf Dienste näher vorgestellt, die inzwischen größtenteils in den Regelbetrieb der Hochschule übergegangen sind: die Videoplattform Media.UP, die mobile App Reflect.UP, die persönliche Lernumgebung Campus. UP, das Self-Service-Portal Cook.UP und das Anzeigesystem Freiraum.UP. Dabei wird jeweils ein technischer Blick „unter die Haube“ verbunden mit einer Erläuterung der Nutzungsmöglichkeiten, denen eine aktuelle Einschätzung von Lehrenden und Studierenden der Hochschule gegenübergestellt wird. Der Beitrag schließt mit einer Einbettung der vorgestellten Entwicklungen in einen größeren Kontext und einem Ausblick auf die weiterhin anstehenden Aufgaben. KW - Digitale Medien KW - E-Learning KW - Persönliche Lernumgebung KW - E-Portfolio KW - Mobile App KW - IT-Infrastruktur Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-493024 SN - 978-3-86956-498-2 SN - 2192-1075 SN - 2192-1083 IS - 6 SP - 235 EP - 255 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Dug, Mehmed A1 - Weidling, Stefan A1 - Sogomonyan, Egor A1 - Jokic, Dejan A1 - Krstić, Miloš T1 - Full error detection and correction method applied on pipelined structure using two approaches JF - Journal of circuits, systems and computers N2 - In this paper, two approaches are evaluated using the Full Error Detection and Correction (FEDC) method for a pipelined structure. The approaches are referred to as Full Duplication with Comparison (FDC) and Concurrent Checking with Parity Prediction (CCPP). Aforementioned approaches are focused on the borderline cases of FEDC method which implement Error Detection Circuit (EDC) in two manners for the purpose of protection of combinational logic to address the soft errors of unspecified duration. The FDC approach implements a full duplication of the combinational circuit, as the most complex and expensive implementation of the FEDC method, and the CCPP approach implements only the parity prediction bit, being the simplest and cheapest technique, for soft error detection. Both approaches are capable of detecting soft errors in the combinational logic, with single faults being injected into the design. On the one hand, the FDC approach managed to detect and correct all injected faults while the CCPP approach could not detect multiple faults created at the output of combinational circuit. On the other hand, the FDC approach leads to higher power consumption and area increase compared to the CCPP approach. KW - Fault tolerance KW - FEDC KW - EDC Y1 - 2020 U6 - https://doi.org/10.1142/S0218126620502187 SN - 0218-1266 SN - 1793-6454 VL - 29 IS - 13 PB - World Scientific CY - Singapore ER - TY - JOUR A1 - Li, Yuanqing A1 - Breitenreiter, Anselm A1 - Andjelkovic, Marko A1 - Chen, Junchao A1 - Babic, Milan A1 - Krstić, Miloš T1 - Double cell upsets mitigation through triple modular redundancy JF - Microelectronics Journal N2 - A triple modular redundancy (TMR) based design technique for double cell upsets (DCUs) mitigation is investigated in this paper. This technique adds three extra self-voter circuits into a traditional TMR structure to enable the enhanced error correction capability. Fault-injection simulations show that the soft error rate (SER) of the proposed technique is lower than 3% of that of TMR. The implementation of this proposed technique is compatible with the automatic digital design flow, and its applicability and performance are evaluated on an FIFO circuit. KW - Triple modular redundancy (TMR) KW - Double cell upsets (DCUs) Y1 - 2019 U6 - https://doi.org/10.1016/j.mejo.2019.104683 SN - 0026-2692 SN - 1879-2391 VL - 96 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Kuentzer, Felipe A. A1 - Krstić, Miloš T1 - Soft error detection and correction architecture for asynchronous bundled data designs JF - IEEE transactions on circuits and systems N2 - In this paper, an asynchronous design for soft error detection and correction in combinational and sequential circuits is presented. The proposed architecture is called Asynchronous Full Error Detection and Correction (AFEDC). A custom design flow with integrated commercial EDA tools generates the AFEDC using the asynchronous bundled-data design style. The AFEDC relies on an Error Detection Circuit (EDC) for protecting the combinational logic and fault-tolerant latches for protecting the sequential logic. The EDC can be implemented using different detection methods. For this work, two boundary variants are considered, the Full Duplication with Comparison (FDC) and the Partial Duplication with Parity Prediction (PDPP). The AFEDC architecture can handle single events and timing faults of arbitrarily long duration as well as the synchronous FEDC, but additionally can address known metastability issues of the FEDC and other similar synchronous architectures and provide a more practical solution for handling the error recovery process. Two case studies are developed, a carry look-ahead adder and a pipelined non-restoring array divider. Results show that the AFEDC provides equivalent fault coverage when compared to the FEDC while reducing area, ranging from 9.6% to 17.6%, and increasing energy efficiency, which can be up to 6.5%. KW - circuit Faults KW - latches KW - Fault tolerance KW - Fault tolerant systems KW - timing KW - clocks KW - transient analysis KW - asynchrounous design KW - soft errors KW - transient Faults KW - bundled data KW - click controller KW - self-checking KW - concurrent checking KW - DMR KW - TMR Y1 - 2020 U6 - https://doi.org/10.1109/TCSI.2020.2998911 SN - 1549-8328 SN - 1558-0806 VL - 67 IS - 12 SP - 4883 EP - 4894 PB - Institute of Electrical and Electronics Engineers CY - New York ER - TY - JOUR A1 - Fandiño, Jorge A1 - Lifschitz, Vladimir A1 - Lühne, Patrick A1 - Schaub, Torsten H. T1 - Verifying tight logic programs with Anthem and Vampire JF - Theory and practice of logic programming N2 - This paper continues the line of research aimed at investigating the relationship between logic programs and first-order theories. We extend the definition of program completion to programs with input and output in a subset of the input language of the ASP grounder gringo, study the relationship between stable models and completion in this context, and describe preliminary experiments with the use of two software tools, anthem and vampire, for verifying the correctness of programs with input and output. Proofs of theorems are based on a lemma that relates the semantics of programs studied in this paper to stable models of first-order formulas. Y1 - 2020 U6 - https://doi.org/10.1017/S1471068420000344 SN - 1471-0684 SN - 1475-3081 VL - 20 IS - 5 SP - 735 EP - 750 PB - Cambridge Univ. Press CY - Cambridge [u.a.] ER - TY - JOUR A1 - Cabalar, Pedro A1 - Fandiño, Jorge A1 - Garea, Javier A1 - Romero, Javier A1 - Schaub, Torsten H. T1 - Eclingo BT - a solver for epistemic logic programs JF - Theory and practice of logic programming N2 - We describe eclingo, a solver for epistemic logic programs under Gelfond 1991 semantics built upon the Answer Set Programming system clingo. The input language of eclingo uses the syntax extension capabilities of clingo to define subjective literals that, as usual in epistemic logic programs, allow for checking the truth of a regular literal in all or in some of the answer sets of a program. The eclingo solving process follows a guess and check strategy. It first generates potential truth values for subjective literals and, in a second step, it checks the obtained result with respect to the cautious and brave consequences of the program. This process is implemented using the multi-shot functionalities of clingo. We have also implemented some optimisations, aiming at reducing the search space and, therefore, increasing eclingo 's efficiency in some scenarios. Finally, we compare the efficiency of eclingo with two state-of-the-art solvers for epistemic logic programs on a pair of benchmark scenarios and show that eclingo generally outperforms their obtained results. KW - Answer Set Programming KW - Epistemic Logic Programs KW - Non-Monotonic KW - Reasoning KW - Conformant Planning Y1 - 2020 U6 - https://doi.org/10.1017/S1471068420000228 SN - 1471-0684 SN - 1475-3081 VL - 20 IS - 6 SP - 834 EP - 847 PB - Cambridge Univ. Press CY - New York ER - TY - JOUR A1 - Bordihn, Henning A1 - Vaszil, György T1 - Reversible parallel communicating finite automata systems JF - Acta informatica N2 - We study the concept of reversibility in connection with parallel communicating systems of finite automata (PCFA in short). We define the notion of reversibility in the case of PCFA (also covering the non-deterministic case) and discuss the relationship of the reversibility of the systems and the reversibility of its components. We show that a system can be reversible with non-reversible components, and the other way around, the reversibility of the components does not necessarily imply the reversibility of the system as a whole. We also investigate the computational power of deterministic centralized reversible PCFA. We show that these very simple types of PCFA (returning or non-returning) can recognize regular languages which cannot be accepted by reversible (deterministic) finite automata, and that they can even accept languages that are not context-free. We also separate the deterministic and non-deterministic variants in the case of systems with non-returning communication. We show that there are languages accepted by non-deterministic centralized PCFA, which cannot be recognized by any deterministic variant of the same type. KW - Finite automata KW - Reversibility KW - Systems of parallel communicating KW - automata Y1 - 2021 U6 - https://doi.org/10.1007/s00236-021-00396-9 SN - 0001-5903 SN - 1432-0525 VL - 58 IS - 4 SP - 263 EP - 279 PB - Springer CY - Berlin ; Heidelberg ; New York, NY ER - TY - JOUR A1 - Bordihn, Henning A1 - Holzer, Markus T1 - On the number of active states in finite automata JF - Acta informatica N2 - We introduce a new measure of descriptional complexity on finite automata, called the number of active states. Roughly speaking, the number of active states of an automaton A on input w counts the number of different states visited during the most economic computation of the automaton A for the word w. This concept generalizes to finite automata and regular languages in a straightforward way. We show that the number of active states of both finite automata and regular languages is computable, even with respect to nondeterministic finite automata. We further compare the number of active states to related measures for regular languages. In particular, we show incomparability to the radius of regular languages and that the difference between the number of active states and the total number of states needed in finite automata for a regular language can be of exponential order. Y1 - 2021 U6 - https://doi.org/10.1007/s00236-021-00397-8 SN - 0001-5903 SN - 1432-0525 VL - 58 IS - 4 SP - 301 EP - 318 PB - Springer CY - Berlin ; Heidelberg [u.a.] ER - TY - JOUR A1 - Kreowsky, Philipp A1 - Stabernack, Christian Benno T1 - A full-featured FPGA-based pipelined architecture for SIFT extraction JF - IEEE access : practical research, open solutions / Institute of Electrical and Electronics Engineers N2 - Image feature detection is a key task in computer vision. Scale Invariant Feature Transform (SIFT) is a prevalent and well known algorithm for robust feature detection. However, it is computationally demanding and software implementations are not applicable for real-time performance. In this paper, a versatile and pipelined hardware implementation is proposed, that is capable of computing keypoints and rotation invariant descriptors on-chip. All computations are performed in single precision floating-point format which makes it possible to implement the original algorithm with little alteration. Various rotation resolutions and filter kernel sizes are supported for images of any resolution up to ultra-high definition. For full high definition images, 84 fps can be processed. Ultra high definition images can be processed at 21 fps. KW - Field programmable gate arrays KW - Convolution KW - Signal processing KW - algorithms KW - Kernel KW - Image resolution KW - Histograms KW - Feature extraction KW - Scale-invariant feature transform (SIFT) KW - field-programmable gate array KW - (FPGA) KW - image processing KW - computer vision KW - parallel processing KW - architecture KW - real-time KW - hardware architecture Y1 - 2021 U6 - https://doi.org/10.1109/ACCESS.2021.3104387 SN - 2169-3536 VL - 9 SP - 128564 EP - 128573 PB - Inst. of Electr. and Electronics Engineers CY - New York, NY ER - TY - JOUR A1 - Bauer, Chris A1 - Herwig, Ralf A1 - Lienhard, Matthias A1 - Prasse, Paul A1 - Scheffer, Tobias A1 - Schuchhardt, Johannes T1 - Large-scale literature mining to assess the relation between anti-cancer drugs and cancer types JF - Journal of translational medicine N2 - Background: There is a huge body of scientific literature describing the relation between tumor types and anti-cancer drugs. The vast amount of scientific literature makes it impossible for researchers and physicians to extract all relevant information manually. Methods: In order to cope with the large amount of literature we applied an automated text mining approach to assess the relations between 30 most frequent cancer types and 270 anti-cancer drugs. We applied two different approaches, a classical text mining based on named entity recognition and an AI-based approach employing word embeddings. The consistency of literature mining results was validated with 3 independent methods: first, using data from FDA approvals, second, using experimentally measured IC-50 cell line data and third, using clinical patient survival data. Results: We demonstrated that the automated text mining was able to successfully assess the relation between cancer types and anti-cancer drugs. All validation methods showed a good correspondence between the results from literature mining and independent confirmatory approaches. The relation between most frequent cancer types and drugs employed for their treatment were visualized in a large heatmap. All results are accessible in an interactive web-based knowledge base using the following link: . Conclusions: Our approach is able to assess the relations between compounds and cancer types in an automated manner. Both, cancer types and compounds could be grouped into different clusters. Researchers can use the interactive knowledge base to inspect the presented results and follow their own research questions, for example the identification of novel indication areas for known drugs. KW - Literature mining KW - Anti-cancer drugs KW - Tumor types KW - Word embeddings KW - Database Y1 - 2021 U6 - https://doi.org/10.1186/s12967-021-02941-z SN - 1479-5876 VL - 19 IS - 1 PB - BioMed Central CY - London ER - TY - JOUR A1 - Huang, Yizhen A1 - Richter, Eric A1 - Kleickmann, Thilo A1 - Wiepke, Axel A1 - Richter, Dirk T1 - Classroom complexity affects student teachers’ behavior in a VR classroom JF - Computers & education : an international journal N2 - Student teachers often struggle to keep track of everything that is happening in the classroom, and particularly to notice and respond when students cause disruptions. The complexity of the classroom environment is a potential contributing factor that has not been empirically tested. In this experimental study, we utilized a virtual reality (VR) classroom to examine whether classroom complexity affects the likelihood of student teachers noticing disruptions and how they react after noticing. Classroom complexity was operationalized as the number of disruptions and the existence of overlapping disruptions (multidimensionality) as well as the existence of parallel teaching tasks (simultaneity). Results showed that student teachers (n = 50) were less likely to notice the scripted disruptions, and also less likely to respond to the disruptions in a comprehensive and effortful manner when facing greater complexity. These results may have implications for both teacher training and the design of VR for training or research purpose. This study contributes to the field from two aspects: 1) it revealed how features of the classroom environment can affect student teachers' noticing of and reaction to disruptions; and 2) it extends the functionality of the VR environment-from a teacher training tool to a testbed of fundamental classroom processes that are difficult to manipulate in real-life. KW - Augmented and virtual reality KW - Simulations KW - Improving classroom KW - teaching KW - Media in education KW - Pedagogical issues Y1 - 2021 U6 - https://doi.org/10.1016/j.compedu.2020.104100 SN - 0360-1315 SN - 1873-782X VL - 163 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Hawro, Tomasz A1 - Przybylowicz, Katarzyna A1 - Spindler, Max A1 - Hawro, Marlena A1 - Steć, Michał A1 - Altrichter, Sabine A1 - Weller, Karsten A1 - Magerl, Markus A1 - Reidel, Ulrich A1 - Alarbeed, Ezzat A1 - Alraboni, Ola A1 - Maurer, Marcus A1 - Metz, Martin T1 - The characteristics and impact of pruritus in adult dermatology patients BT - a prospective, cross-sectional study JF - Journal of the American Academy of Dermatology N2 - Background: Pruritus often accompanies chronic skin diseases, exerting considerable burden on many areas of patient functioning; this burden and the features of pruritus remain insufficiently characterized. Objective: To investigate characteristics, including localization patterns, and burden of pruritus in patients with chronic dermatoses. Methods: We recruited 800 patients with active chronic skin diseases. We assessed pruritus intensity, localization, and further characteristics. We used validated questionnaires to assess quality of life, work productivity and activity impairment, anxiety, depression, and sleep quality. Results: Nine out of every 10 patients had experienced pruritus throughout their disease and 73% in the last 7 days. Pruritus often affected the entire body and was not restricted to skin lesions. Patients with moderate to severe pruritus reported significantly more impairment to their sleep quality and work productivity, and they were more depressed and anxious than control individuals and patients with mild or no pruritus. Suicidal ideations were highly prevalent in patients with chronic pruritus (18.5%) and atopic dermatitis (11.8%). Conclusions: Pruritus prevalence and intensity are very high across all dermatoses studied; intensity is linked to impairment in many areas of daily functioning. Effective treatment strategies are urgently required to treat pruritus and the underlying skin disease. ( J Am Acad Dermatol 2021;84:691-700.) KW - activity KW - anxiety KW - depression KW - pruritus KW - quality of life KW - sleep quality KW - suicidal ideations KW - work productivity Y1 - 2021 U6 - https://doi.org/10.1016/J.JAAD.2020.08.035 SN - 0190-9622 SN - 1097-6787 VL - 84 IS - 3 SP - 691 EP - 700 PB - Elsevier CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Middelanis, Robin A1 - Willner, Sven N. A1 - Otto, Christian A1 - Kuhla, Kilian A1 - Quante, Lennart A1 - Levermann, Anders T1 - Wave-like global economic ripple response to Hurricane Sandy JF - Environmental research letters : ERL / Institute of Physics N2 - Tropical cyclones range among the costliest disasters on Earth. Their economic repercussions along the supply and trade network also affect remote economies that are not directly affected. We here simulate possible global repercussions on consumption for the example case of Hurricane Sandy in the US (2012) using the shock-propagation model Acclimate. The modeled shock yields a global three-phase ripple: an initial production demand reduction and associated consumption price decrease, followed by a supply shortage with increasing prices, and finally a recovery phase. Regions with strong trade relations to the US experience strong magnitudes of the ripple. A dominating demand reduction or supply shortage leads to overall consumption gains or losses of a region, respectively. While finding these repercussions in historic data is challenging due to strong volatility of economic interactions, numerical models like ours can help to identify them by approaching the problem from an exploratory angle, isolating the effect of interest. For this, our model simulates the economic interactions of over 7000 regional economic sectors, interlinked through about 1.8 million trade relations. Under global warming, the wave-like structures of the economic response to major hurricanes like the one simulated here are likely to intensify and potentially overlap with other weather extremes. KW - supply chains KW - Hurricane Sandy KW - economic ripples KW - extreme weather KW - impacts KW - loss propagation KW - natural disasters Y1 - 2021 U6 - https://doi.org/10.1088/1748-9326/ac39c0 SN - 1748-9326 VL - 16 IS - 12 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Quante, Lennart A1 - Willner, Sven N. A1 - Middelanis, Robin A1 - Levermann, Anders T1 - Regions of intensification of extreme snowfall under future warming JF - Scientific reports N2 - Due to climate change the frequency and character of precipitation are changing as the hydrological cycle intensifies. With regards to snowfall, global warming has two opposing influences; increasing humidity enables intense snowfall, whereas higher temperatures decrease the likelihood of snowfall. Here we show an intensification of extreme snowfall across large areas of the Northern Hemisphere under future warming. This is robust across an ensemble of global climate models when they are bias-corrected with observational data. While mean daily snowfall decreases, both the 99th and the 99.9th percentiles of daily snowfall increase in many regions in the next decades, especially for Northern America and Asia. Additionally, the average intensity of snowfall events exceeding these percentiles as experienced historically increases in many regions. This is likely to pose a challenge to municipalities in mid to high latitudes. Overall, extreme snowfall events are likely to become an increasingly important impact of climate change in the next decades, even if they will become rarer, but not necessarily less intense, in the second half of the century. Y1 - 2021 U6 - https://doi.org/10.1038/s41598-021-95979-4 SN - 2045-2322 VL - 11 IS - 1 PB - Macmillan Publishers Limited, part of Springer Nature CY - Berlin ER -