TY - JOUR A1 - Sticher, Heike A1 - Czepluch, Christine A1 - Mätzener, Flurina A1 - Wilmes, Stefanie A1 - Hadert, Sandra A1 - Frank, Ulrike A1 - Mäder, Mark T1 - Dekanülierungsmanagment bei Patienten mit respiratorischen Beeinträchtigungen und Dysphagie Y1 - 2011 ER - TY - JOUR A1 - Westermann, Antje A1 - Stadie, Nicole A1 - Frank, Ulrike T1 - Messung der Atem-Schluck-Koordination während normalem Schluck und unter Anwendung des Mendelsohn- Manövers Y1 - 2011 ER - TY - JOUR A1 - Düsterhöft, Stefanie A1 - Frank, Ulrike T1 - Das PNF-Konzept Anwendung in der orofacialen Therapie Y1 - 2011 ER - TY - JOUR A1 - Frank, Ulrike T1 - Wie viel Schlucken ist normal? Normdaten in der Diagnostik und Therapie bei Dysphagie Y1 - 2012 ER - TY - JOUR A1 - Jäckel, Annemarie A1 - Frank, Ulrike T1 - Effekte des Mendelsohn Manövers auf die Atem-Schluck-Koordination : eine Untersuchung der intra- individuellen Variation bei gesunden Erwachsenen Y1 - 2012 ER - TY - JOUR A1 - Schindler, Wencke A1 - Frank, Ulrike T1 - Wasserschlucktests in der klinischen Dysphagiediagnostik : Einzelschluckvolumen als Prädikator für die sequentielle Schluckrate? Y1 - 2012 ER - TY - CHAP A1 - Frombach, Janna A1 - Rancan, Fiorenza A1 - Fleige, Emanuel A1 - Haag, Rainer A1 - Schumacher, Frank A1 - Kleuser, Burkhard A1 - Yamamoto, Kenji A1 - Rühl, Eckart A1 - Blume-Peytavi, Ulrike A1 - Vogt, Annika T1 - Skin penetration and dexamethasone release from polymer nanoparticles in ex vivo human skin T2 - The journal of investigative dermatology Y1 - 2015 SN - 0022-202X SN - 1523-1747 VL - 135 SP - S52 EP - S52 PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Mueller-Nordhorn, Jacqueline A1 - Muckelbauer, Rebecca A1 - Englert, Heike A1 - Grittner, Ulrike A1 - Berger, Hendrike A1 - Sonntag, Frank A1 - Völler, Heinz A1 - Prugger, Christof A1 - Wegscheider, Karl A1 - Katus, Hugo A. A1 - Willich, Stefan N. T1 - Longitudinal association between body mass index and health-related quality of life JF - PLoS one N2 - Objective: Health-related quality of life (HRQoL) is an important outcome in individuals with a high risk for cardiovascular diseases. We investigated the association of HRQoL and body mass index (BMI) as an indicator for obesity. Design: Secondary longitudinal analysis of the ORBITAL study, an intervention study which included high-risk cardiovascular primary care patients with hypercholesterolemia and an indication for statin therapy. Methods: HRQoL was determined with the generic Short Form (SF)-12 health status instrument. Body weight and height were assessed at baseline and at months 6, 12, 18, 24, 30, and 36. We used a linear and a linear mixed-effects regression model to investigate the association between BMI and SF-12 summary scores at baseline as well as between change in BMI and SF-12 summary scores over 3 years. We adjusted for age, sex, smoking status, and in the longitudinal analysis also for the study arm and its interaction term with time. Results: Of the 7640 participants who completed the baseline questionnaire, 6726 participants (mean age: 61 years) were analyzed. The baseline BMI was inversely associated with physical and mental SF-12 summary scores (beta [95% CI] per 1 kg/ m(2) : -0.36 [-0.41; -0.30] and -0.05 [-0.11; -0.00], respectively). A significant association between the change in BMI and physical SF-12 summary scores over time was only present in women (-0.18 [-0.27; -0.09]) and only in obese participants (-0.19 [-0.29; -0.10]). A change in BMI was directly associated with mental SF-12 summary scores (0.12 [0.06; 0.19]) in the total population. Conclusion: Increases in BMI were associated with decreases in physical HRQoL, particularly in obese individuals and in women. In contrast, the mental HRQoL seemed to increase with increasing BMI over time. Thus, body weight management with respect to the HRQoL should be evaluated differentially by sex and body weight status. Y1 - 2014 U6 - https://doi.org/10.1371/journal.pone.0093071 SN - 1932-6203 VL - 9 IS - 3 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Frank, Ulrike T1 - Sehen hilft Lernen: sEMG Biofeedback in der Dysphagietherapie JF - Spektrum Patholinguistik (Band 10) - Schwerpunktthema: Panorama Patholinguistik: Sprachwissenschaft trifft Sprachtherapie Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-405081 SN - 1866-9085 IS - 10 SP - 73 EP - 89 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Bykova, Ksenia A1 - Frank, Ulrike T1 - Scale for an Assessment of Risk of Aspiration, oder SARA: Aspirationsscreening für Kinder mit Cerebralparese in Russland JF - Spektrum Patholinguistik (Band 10) - Schwerpunktthema: Panorama Patholinguistik: Sprachwissenschaft trifft Sprachtherapie Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-405160 SN - 1866-9085 IS - 10 SP - 115 EP - 121 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Wilzek, Alexa A1 - Frank, Ulrike A1 - van den Engl-Hoek, Lenie A1 - Huckabee, Maggie-Lee T1 - Normdatenerhebung für den »Test of Mastication and Swallowing Solids« für Kinder und Jugendliche im Altersbereich von 4 bis 14 Jahren JF - Spektrum Patholinguistik (Band 10) - Schwerpunktthema: Panorama Patholinguistik: Sprachwissenschaft trifft Sprachtherapie Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-405195 SN - 1866-9085 IS - 10 SP - 123 EP - 129 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Balzer, Julia A1 - Ebert, Susanne A1 - Frank, Ulrike T1 - When life gives you lemons... Der Einfluss visueller Stimuli auf Schluckfrequenz und Speichelproduktion JF - Spektrum Patholinguistik (Band 10) - Schwerpunktthema: Panorama Patholinguistik: Sprachwissenschaft trifft Sprachtherapie Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-405204 SN - 1866-9085 IS - 10 SP - 131 EP - 140 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Kaps, Hella A1 - Frank, Ulrike A1 - Huckabee, Maggie-Lee T1 - Test of Masticating and Swallowing Solids (TOMASS) BT - Normdatenerhebung an in Deutschland lebenden Erwachsenen im Alter von 20 bis 94 Jahren JF - Spektrum Patholinguistik (Band 10) - Schwerpunktthema: Panorama Patholinguistik: Sprachwissenschaft trifft Sprachtherapie Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-405223 SN - 1866-9085 IS - 10 SP - 141 EP - 156 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Müller, Nina A1 - Beer, Carola de A1 - Frank, Ulrike T1 - Ist die therapeutische Mundpflege bei Dysphagiepatient*innen verschwendete Zeit? BT - ein narrativer Review zu Effekten der Mundpflege auf die Pneumoniehäufigkeit und Ableitung einer Handlungsempfehlung BT - a narrative review on the effects of oral care on pneumonia risk and guidelines for an effective and structured approach JF - Sprache, Stimme, Gehör : Zeitschrift für Kommunikationsstörungen N2 - Aspirationspneumonien sind eine häufige Todesursache bei Dysphagiepatient*innen. In diesem Beitrag wird durch die Evaluation relevanter Studien die Frage untersucht, ob die therapeutische Mundpflege bei Dysphagiepatient*innen zur Verringerung des Pneumonierisikos beitragen kann. Zudem wird auf dieser Grundlage eine Handlungsempfehlung für die Umsetzung der Mundpflege entwickelt. Die ausgewählten Studien zeigen, dass die Mundpflege einen positiven Effekt auf das Pneumonie-Risiko von Dysphagiepatient*innen hat. Sie sollte auf den Grundsätzen Einfachheit, Sicherheit, Arbeitskräfteentlastung, Wirksamkeit, Universalität, Wirtschaftlichkeit und vollständige Mundpflege aller Teile der Mundhöhle beruhen und nimmt weniger als fünf Minuten täglich ein. Sie bereitet durch die taktile Stimulation auf die anschließende Dysphagie-Therapie vor und ist somit sinnvoll investierte Therapiezeit. N2 - Aspiration pneumonia is a common cause of death in dysphagia patients. In this review, we investigate whether a structured oral care approach can help to reduce pneumonia risk in dysphagic patients. In addition, guidelines for the implementation of oral care on the basis of the analyzed studies are presented. Oral care has positive effects on the risk of pneumonia in dysphagia patients. Oral care should be based on the principles of simplicity, safety, efficiency and effectiveness, universality and economy and it should include all parts of the oral cavity. Effective oral care takes less than five minutes a day. The tactile stimulation prepares the patient for dysphagia therapy and can be considered wisely-invested time. T2 - Is oral care for dysphagic patients wasted time? KW - oral care KW - dysphagia KW - pneumonia KW - Therapeutische Mundpflege KW - Dysphagie KW - Pneumonie Y1 - 2022 U6 - https://doi.org/10.1055/a-1714-1587 SN - 0342-0477 SN - 1439-1260 VL - 46 IS - 03 SP - 150 EP - 155 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Tan, Sarah A1 - Düring, Sarah A1 - Wilde, Alina A1 - Hamburger, Lara A1 - Fritzsche, Tom A1 - Felsing, Ulrike A1 - Lauer, Norina A1 - Corsten, Sabine A1 - Ostermann, Frank A1 - Nonn, Kerstin A1 - Nerz, Verena A1 - Neumann, Sandra A1 - Zauke, Svenja A1 - Sandrieser, Patricia A1 - Steinberg, Romy Simone A1 - Thurmann, Anika A1 - Dörr, Fiona A1 - Bilda, Kerstin A1 - Kluth, Alicia A1 - Lemire-Tremblay, Marilyne A1 - Jamey, Kevin A1 - Dalla Bella, Simone A1 - Falk, Simone A1 - Kleingünther, Constanze A1 - Gabler, Katrin A1 - Elligsen, Chiara A1 - Weiland, Katharina A1 - Wiehe, Lea A1 - Wahl, Michael A1 - Binczyk, Sarah A1 - Staebel, Cornelia A1 - Jung, Stefanie A1 - Eikerling, Maren A1 - Czok, Clara A1 - Sallat, Stephan A1 - Collasius, Valerie A1 - Grahovac, Tena ED - Tan, Sarah ED - Düring, Sarah ED - Wilde, Alina ED - Hamburger, Lara ED - Fritzsche, Tom T1 - Spektrum Patholinguistik Band 16. Schwerpunktthema: Schnittstelle Alltag: Transfer und Teilhabe in der Sprachtherapie N2 - Das 16. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Schnittstelle Alltag: Transfer und Teilhabe in der Sprachtherapie« fand am 19.11.2022 als Online-Veranstaltung statt. Das Herbsttreffen wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl), seit 2021 vom Deutschen Bundesverband für akademische Sprachtherapie und Logopädie (dbs) in Kooperation mit der Universität Potsdam durchgeführt. Der vorliegende Tagungsband beinhaltet die Vorträge zum Schwerpunktthema sowie die Posterpräsentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis. N2 - The Sixteenth Autumn Meeting Patholinguistics with its main topic »Interface everyday life: Transfer and participation in speech/language therapy« took place online on the 19th of November 2022. This annual meeting has been organised since 2007 by the Association for Patholinguistics (vpl), since 2021 by the German Federal Association for Academic Speech/Language Therapy and Logopaedics (dbs) in cooperation with the University of Potsdam. The present proceedings feature the presentations on the main topic as well as articles from the poster session covering a broad range of areas in research and practice of speech/language therapy. T3 - Spektrum Patholinguistik - 16 KW - Patholinguistik KW - Sprachtherapie KW - Transfer KW - Teilhabe KW - patholinguistics KW - speech/language therapy KW - transfer KW - participation Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-590433 SN - 978-3-86956-559-0 SN - 1866-9433 SN - 1869-3822 IS - 16 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Ette, Ottmar A1 - Knobloch, Eberhard A1 - Schwarz, Oliver A1 - Werner, Petra A1 - Suckow, Christian A1 - Jobst, Anne A1 - Schmuck, Thomas A1 - Ringmacher, Manfred A1 - Tintemann, Ute A1 - Leitner, Ulrike A1 - Holl, Frank A1 - Panwitz, Sebastian A1 - Péaud, Laura A1 - Holtz, Bärbel A1 - Folkerts, Menso A1 - Päßler, Ulrich A1 - Roba, Bill ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - HiN : Alexander von Humboldt im Netz = Ingo Schwarz zum 65. Geburtstag T2 - HIN : Alexander von Humboldt im Netz ; international review for Humboldtian studies N2 - Inhalt: Alexander von Humboldt-Forschungsstelle: Ingo Schwarz zum 65. Geburtstag Ottmar Ette: Findung und Erfindung einer Leserschaft. Neuere Editionsprojekte zu Alexander von Humboldt als Grundlage und Herausforderung künftigen Forschens Eberhard Knobloch: Alexandre de Humboldt et le Marquis de Laplace Oliver Schwarz: Alexander von Humboldt als astronomischer Arbeiter, Diskussionspartner und Ideengeber Petra Werner: Innenwelten und bleiche Gärten. Alexander von Humboldt untertage und in der Caripe-Höhle Christian Suckow: Alexander von Humboldt in Ust’-Kamenogorsk Anne Jobst: Neue Briefe Christian Gottfried Ehrenbergs an Alexander von Humboldt Thomas Schmuck: Humboldt, Baer und die Evolution Manfred Ringmacher: Zwei Briefe auf Guaraní in Alexander von Humboldts Handschrift Ute Tintemann: Julius Klaproths Mithridates-Projekt, Alexander von Humboldt und das Verlagshaus Cotta Ulrike Leitner: „Ja! Wenn Berlin Bonn wäre!“ Friedrich Rückerts Berufung nach Berlin Frank Holl: „Zur Freiheit bestimmt“ – Alexander von Humboldts Blick auf die Kulturen der Welt Sebastian Panwitz: Das Humboldt-Mendelssohn-Haus Jägerstraße 22. Ein Quellenfund Laura Péaud: Du Mexique à l‘Oural : l‘expertise humboldtienne au service du politique Bärbel Holtz: „Cicerone“ des Königs? Alexander von Humboldt und Friedrich Wilhelm III. Menso Folkerts: Ein unerwartetes Zusammentreffen in Sanssouci. Alexander von Humboldt und Karl Ludwig Hencke an der Tafel Friedrich Wilhelms IV. Ulrich Päßler: Preußens Mann in Washington. Fünf Briefe Friedrich von Gerolts an Alexander von Humboldt (1858/1859) Bill Roba: German-Iowan Strategies in Celebrating the Centennial of Alexander von Humboldt’s Birth Regina Mikosch: Ingo Schwarz‘ Veröffentlichungen zur Alexander von Humboldt Über die Autoren T3 - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies - XV.2014, 29 KW - Humboldt KW - Alexander von Humboldt KW - Humboldt-Forschung KW - Universität Potsdam KW - BBAW KW - Brief KW - Briefwechsel KW - Editionsprojekte KW - Reisemanuskripte KW - Reisetagebücher KW - amerikanische Reisetagebücher KW - Marquis de Laplace KW - Laplace KW - Astronomie KW - Caripe KW - untertage KW - Höhlenforschung KW - Ust'-Kamenogorsk KW - Christian Gottfried Ehrenberg KW - Baer KW - Evolution KW - Guaraní KW - Julius Klaproth KW - Mithriades KW - Cotta KW - Bonn KW - Berlin KW - Friedrich Rückert KW - Kulturen der Welt KW - Freiheit KW - Sklaverei KW - Abolitionismus KW - Mendelssohn KW - Jägerstraße 22 KW - Mexiko KW - Mexico KW - Neu-Spanien KW - Nouvelle Espagne KW - Oural KW - Ural KW - Politik KW - Friedrich Wilhelm III. KW - Preußen KW - Sanssouci KW - Karl Ludwig Hencke KW - Friedrich Wilhelm IV. KW - Washington D.C. KW - Friedrich von Gerolt KW - Iowa KW - Hundertjahr-Feier KW - Gedenkfeier KW - US-Rezeption KW - Ingo Schwarz Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-85033 SN - 1617-5239 SN - 2568-3543 VL - XV IS - 29 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Iven, Claudia A1 - Hansen, Bernd A1 - Anders, Kristina A1 - Starke, Andreas A1 - Richardt, Kirsten A1 - Prüß, Holger A1 - El Meskioui, Martina A1 - Haase, Tobias A1 - Mahlberg, Lea A1 - Wiehe, Lea A1 - de Beer, Carola A1 - Niepelt Karampamapa, Rebekka A1 - Hofmann, Andrea A1 - Stadie, Nicole A1 - Hanne, Sandra A1 - Thomson, Jenny A1 - Schäfer, Blanca A1 - Huttenlauch, Clara A1 - Wartenburger, Isabell A1 - Weiland, Katharina A1 - Wirsam, Anke A1 - Hartung, Julia A1 - Wahl, Michael A1 - Unger, Julia A1 - Buschmann, Anke A1 - Seefeld, Martin A1 - Bethge, Anita A1 - Fieder, Nora A1 - Rahman, Rasha Abdel A1 - Nousair, Iman A1 - Klassert, Annegret A1 - Wellmann, Caroline A1 - Verbree, Rahel A1 - van Rij, Jacolien A1 - Sprenger, Simone A1 - Mähl, Anna Luisa A1 - Schneider, Kathleen A1 - Kutz, Anne A1 - Kaps, Hella A1 - Frank, Ulrike A1 - Brekeller, Sophie A1 - Ryll, Katja ED - Breitenstein, Sarah ED - Burmester, Juliane ED - Yetim, Özlem ED - Fritzsche, Tom T1 - Spektrum Patholinguistik Band 12. Schwerpunktthema: Weg(e) mit dem Stottern: Therapie und Selbsthilfe für Kinder und Erwachsene T2 - Spektrum Patholinguistik N2 - Das 12. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Weg(e) mit dem Stottern: Therapie und Selbsthilfe für Kinder und Erwachsene« fand am 24.11.2018 in Potsdam statt. Das Herbsttreffen wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Der vorliegende Tagungsband beinhaltet die Vorträge zum Schwerpunktthema sowie Beiträge der Posterpräsentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis. N2 - The Twelfth Autumn Meeting Patholinguistics (Herbsttreffen Patholinguistik) with its main topic »Away/A way with stuttering: Therapy and self-help for children and adults« took place in Potsdam on November 24 2018. This annual meeting has been organised since 2007 by the Association for Patholinguistics (Verband für Patholinguistik e.V./vpl). The present proceedings contain all talks on the main topic as well as contributions from the poster session covering a broad range of areas in speech/language therapy research and practice. T3 - Spektrum Patholinguistik - 12 KW - Patholinguistik KW - Sprachtherapie KW - Stottern KW - Redeflussstörungen KW - Selbsthilfe KW - patholinguistics KW - speech/language therapy KW - stuttering KW - fluency disorder KW - self-help Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-437002 SN - 978-3-86956-479-1 SN - 1866-9085 SN - 1866-9433 IS - 12 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Frank, Ulrike A1 - Radtke, Julia A1 - Nienstedt, Julie Cläre A1 - Pötter-Nerger, Monika A1 - Schönwald, Beate A1 - Buhmann, Carsten A1 - Gerloff, Christian A1 - Niessen, Almut A1 - Flügel, Till A1 - Koseki, Jana-Christiane A1 - Pflug, Christina T1 - Dysphagia screening in Parkinson's Disease BT - a diagnostic accuracy cross-sectional study investigating the applicability of the Gugging Swallowing Screen (GUSS) JF - Neurogastroenterology and motility N2 - Background Simple water-swallowing screening tools are not predictive of aspiration and dysphagia in patients with Parkinson's Disease (PD). We investigated the diagnostic accuracy of a multi-texture screening tool, the Gugging Swallowing Screen (GUSS) to identify aspiration and dysphagia/penetration in PD patients compared to flexible endoscopic evaluation of swallowing (FEES). Methods Swallowing function was evaluated in 51 PD participants in clinical 'on-medication' state with the GUSS and a FEES examination according to standardized protocols. Inter-rater reliability and convergent validity were determined and GUSS- and FEES-based diet recommendations were compared. Key Results Inter-rater reliability of GUSS ratings was high (r(s) = 0.8; p < 0.001). Aspiration was identified by the GUSS with a sensitivity of 50%, and specificity of 51.35% (PPV 28%, NPV 73%, LR+ 1.03, LR- 0.97), dysphagia/penetration was identified with 72.97% sensitivity and 35.71% specificity (PPV 75%, NPV 33.33%, LR+ 1.14, LR- 0.76). Agreement between GUSS- and FEES-based diet recommendations was low (r(s) = 0.12, p = 0.42) with consistent NPO (Nil per Os) allocation by GUSS and FEES in only one participant. Conclusions and Inferences The multi-texture screening tool GUSS in its current form, although applicable with good inter-rater reliability, does not detect aspiration in PD patients with acceptable accuracy. Modifications of the GUSS parameters "coughing," "voice change" and "delayed swallowing" might enhance validity. The GUSS' diet recommendations overestimate the need for oral intake restriction in PD patients and should be verified by instrumental swallowing examination. KW - aspiration KW - dysphagia KW - FEES KW - Gugging Swallowing Screen KW - Parkinson' s disease Y1 - 2021 U6 - https://doi.org/10.1111/nmo.14034 SN - 1350-1925 SN - 1365-2982 VL - 33 IS - 5 PB - Wiley CY - Hoboken ER - TY - GEN A1 - Frank, Ulrike A1 - Radtke, Julia A1 - Nienstedt, Julie Cläre A1 - Pötter-Nerger, Monika A1 - Schönwald, Beate A1 - Buhmann, Carsten A1 - Gerloff, Christian A1 - Niessen, Almut A1 - Flügel, Till A1 - Koseki, Jana-Christiane A1 - Pflug, Christina T1 - Dysphagia screening in Parkinson's Disease BT - a diagnostic accuracy cross-sectional study investigating the applicability of the Gugging Swallowing Screen (GUSS) T2 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Background Simple water-swallowing screening tools are not predictive of aspiration and dysphagia in patients with Parkinson's Disease (PD). We investigated the diagnostic accuracy of a multi-texture screening tool, the Gugging Swallowing Screen (GUSS) to identify aspiration and dysphagia/penetration in PD patients compared to flexible endoscopic evaluation of swallowing (FEES). Methods Swallowing function was evaluated in 51 PD participants in clinical 'on-medication' state with the GUSS and a FEES examination according to standardized protocols. Inter-rater reliability and convergent validity were determined and GUSS- and FEES-based diet recommendations were compared. Key Results Inter-rater reliability of GUSS ratings was high (r(s) = 0.8; p < 0.001). Aspiration was identified by the GUSS with a sensitivity of 50%, and specificity of 51.35% (PPV 28%, NPV 73%, LR+ 1.03, LR- 0.97), dysphagia/penetration was identified with 72.97% sensitivity and 35.71% specificity (PPV 75%, NPV 33.33%, LR+ 1.14, LR- 0.76). Agreement between GUSS- and FEES-based diet recommendations was low (r(s) = 0.12, p = 0.42) with consistent NPO (Nil per Os) allocation by GUSS and FEES in only one participant. Conclusions and Inferences The multi-texture screening tool GUSS in its current form, although applicable with good inter-rater reliability, does not detect aspiration in PD patients with acceptable accuracy. Modifications of the GUSS parameters "coughing," "voice change" and "delayed swallowing" might enhance validity. The GUSS' diet recommendations overestimate the need for oral intake restriction in PD patients and should be verified by instrumental swallowing examination. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 854 KW - aspiration KW - dysphagia KW - FEES KW - Gugging Swallowing Screen KW - Parkinson' s disease Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-569625 SN - 1866-8364 IS - 5 ER - TY - BOOK A1 - Nasdala, Gerhard A1 - Möbus, Frank A1 - Stockhorst, Stefanie A1 - Mälzig, Ulrike T1 - Wege nach Weimar : Beiträge der Studentenkolloquien im Rahmen des Modellprojekts Weimarer Klassik und Jenaer Romantik 1996/97 T3 - Veröffentlichungen des Studienprogramms Weimarer Klassik und Jenaer Romantik Y1 - 2001 SN - 3-932289-57-9 VL - 1 PB - Litblockín CY - Fernwald ER - TY - JOUR A1 - Schirrmeister, Lutz A1 - Meyer, Hanno A1 - Andreev, Andrei A1 - Wetterich, Sebastian A1 - Kienast, Frank A1 - Bobrov, Anatoly A1 - Fuchs, Margret A1 - Sierralta, Melanie A1 - Herzschuh, Ulrike T1 - Late Quaternary paleoenvironmental records from the Chatanika River valley near Fairbanks (Alaska) JF - Quaternary science reviews : the international multidisciplinary research and review journal N2 - Perennially-frozen deposits are considered as excellent paleoenvironmental archives similar to lacustrine, deep marine, and glacier records because of the long-term and good preservation of fossil records under stable permafrost conditions. A permafrost tunnel in the Vault Creek Valley (Chatanika River Valley, near Fairbanks) exposes a sequence of frozen deposits and ground ice that provides a comprehensive set of proxies to reconstruct the late Quaternary environmental history of Interior Alaska. The multi-proxy approach includes different dating techniques (radiocarbon-accelerator mass spectrometry [AMS C-14], optically stimulated luminescence [OSL], thorium/uranium radioisotope disequilibria [Th-230/U]), as well as methods of sedimentology, paleoecology, hydrochemistry, and stable isotope geochemistry of ground ice. The studied sequence consists of 36-m-thick late Quaternary deposits above schistose bedrock. Main portions of the sequence accumulated during the early and middle Wisconsin periods. The lowermost unit A consists of about 9-m-thick ice-bonded fluvial gravels with sand and peat lenses. A late Sangamon (MIS 5a) age of unit A is assumed. Spruce forest with birch, larch, and some shrubby alder dominated the vegetation. High presence of Sphagnum spores and Cyperaceae pollen points to mires in the Vault Creek Valley. The overlying unit B consists of 10-m-thick alternating fluvial gravels, loess-like silt, and sand layers, penetrated by small ice wedges. OSL dates support a stadial early Wisconsin (MIS 4) age of unit B. Pollen and plant macrofossil data point to spruce forests with some birch interspersed with wetlands around the site. The following unit C is composed of 15-m-thick ice-rich loess-like and organic-rich silt with fossil bones and large ice wedges. Unit C formed during the interstadial mid-Wisconsin (MIS 3) and stadial late Wisconsin (MIS 2) as indicated by radiocarbon ages. Post-depositional slope processes significantly deformed both, ground ice and sediments of unit C. Pollen data show that spruce forests and wetlands dominated the area. The macrofossil remains of Picea, Larix, and Alnus incana ssp. tenuifolia also prove the existence of boreal coniferous forests during the mid-Wisconsin interstadial, which were replaced by treeless tundra-steppe vegetation during the late Wisconsin stadial. Unit C is discordantly overlain by the 2-m-thick late Holocene deposits of unit D. The pollen record of unit D indicates boreal forest vegetation similar to the modern one. The permafrost record from the Vault Creek tunnel reflects more than 90 ka of periglacial landscape dynamics triggered by fluvial and eolian accumulation, and formation of ice-wedge polygons and post depositional deformation by slope processes. The record represents a typical Wisconsin valley-bottom facies in Central Alaska. (C) 2016 Elsevier Ltd. All rights reserved. KW - Permafrost KW - Interior Alaska KW - Loess KW - Cryolithology KW - Geochronology KW - Paleoecology KW - Landscape dynamics Y1 - 2016 U6 - https://doi.org/10.1016/j.quascirev.2016.02.009 SN - 0277-3791 VL - 147 SP - 259 EP - 278 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Ketelhut, Kerstin A1 - Bittmann, Frank A1 - Scheffler, Christiane A1 - Morgenstern, Ulrike T1 - Vergleichsuntersuchung über Körpermaße und motorische Fähigkeiten bei Kindern Y1 - 2003 ER - TY - GEN A1 - Tian, Fang A1 - Herzschuh, Ulrike A1 - Mischke, Steffen A1 - Schlütz, Frank T1 - What drives the recent intensified vegetation degradation in Mongolia BT - Climate change or human activity? T2 - The Holocene N2 - This study examines the course and driving forces of recent vegetation change in the Mongolian steppe. A sediment core covering the last 55years from a small closed-basin lake in central Mongolia was analyzed for its multi-proxy record at annual resolution. Pollen analysis shows that highest abundances of planted Poaceae and highest vegetation diversity occurred during 1977-1992, reflecting agricultural development in the lake area. A decrease in diversity and an increase in Artemisia abundance after 1992 indicate enhanced vegetation degradation in recent times, most probably because of overgrazing and farmland abandonment. Human impact is the main factor for the vegetation degradation within the past decades as revealed by a series of redundancy analyses, while climate change and soil erosion play subordinate roles. High Pediastrum (a green algae) influx, high atomic total organic carbon/total nitrogen (TOC/TN) ratios, abundant coarse detrital grains, and the decrease of C-13(org) and N-15 since about 1977 but particularly after 1992 indicate that abundant terrestrial organic matter and nutrients were transported into the lake and caused lake eutrophication, presumably because of intensified land use. Thus, we infer that the transition to a market economy in Mongolia since the early 1990s not only caused dramatic vegetation degradation but also affected the lake ecosystem through anthropogenic changes in the catchment area. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 418 KW - central Mongolia KW - grain size KW - human impact KW - lake eutrophication KW - pollen KW - vegetation degradation Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-404201 ER - TY - JOUR A1 - Opitz, Stephan A1 - Wünnemann, Bernd A1 - Aichner, Bernhard A1 - Dietze, Elisabeth A1 - Hartmann, Kai A1 - Herzschuh, Ulrike A1 - IJmker, Janneke A1 - Lehmkuhl, Frank A1 - Li, Shijie A1 - Mischke, Steffen A1 - Plotzki, Anna A1 - Stauch, Georg A1 - Diekmann, Bernhard T1 - Late Glacial and Holocene development of Lake Donggi Cona, north-eastern Tibetan Plateau, inferred from sedimentological analysis JF - Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences N2 - Sediments of Lake Donggi Cona on the northeastern Tibetan Plateau were studied to infer changes in the lacustrine depositional environment, related to climatic and non-climatic changes during the last 19 kyr. The lake today fills a 30x8 km big and 95 m deep tectonic basin, associated with the Kunlun Fault. The study was conducted on a sediment-core transect through the lake basin, in order to gain a complete picture of spatio-temporal environmental change. The recovered sediments are partly finely laminated and are composed of calcareous muds with variable amounts of carbonate micrite, organic matter, detrital silt and clay. On the basis of sedimentological, geochemical, and mineralogical data up to five lithological units (LU) can be distinguished that document distinct stages in the development of the lake system. The onset of the lowermost LU with lacustrine muds above basal sands indicates that lake level was at least 39 m below the present level and started to rise after 19 ka, possibly in response to regional deglaciation. At this time, the lacustrine environment was characterized by detrital sediment influx and the deposition of siliciclastic sediment. In two sediment cores, upward grain-size coarsening documents a lake-level fall after 13 cal ka BP, possibly associated with the late-glacial Younger Dryas stadial. From 11.5 to 4.3 cal ka BP, grain-size fining in sediment cores from the profundal coring sites and the onset of lacustrine deposition at a litoral core site (2 m water depth) in a recent marginal bay of Donggi Cona document lake-level rise during the early to mid-Holocene to at least modern level. In addition, high biological productivity and pronounced precipitation of carbonate micrites are consistent with warm and moist climate conditions related to an enhanced influence of summer monsoon. At 4.3 cal ka BP the lake system shifted from an aragonite- to a calcite-dominated system, indicating a change towards a fully open hydrological lake system. The younger clay-rich sediments are moreover non-laminated and lack any diagenetic sulphides, pointing to fully ventilated conditions, and the prevailing absence of lake stratification. This turning point in lake history could imply either a threshold response to insolation-forced climate cooling or a response to a non-climatic trigger, such as an erosional event or a tectonic pulse that induced a strong earthquake, which is difficult to decide from our data base. KW - China KW - Monsoon KW - Paleolimnology KW - Multi-site study KW - Aragonite KW - XRF KW - XRD KW - Sedimentology Y1 - 2012 U6 - https://doi.org/10.1016/j.palaeo.2012.04.013 SN - 0031-0182 VL - 337 IS - 23 SP - 159 EP - 176 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tian, Fang A1 - Herzschuh, Ulrike A1 - Mischke, Steffen A1 - Schluetz, Frank T1 - What drives the recent intensified vegetation degradation in Mongolia - Climate change or human activity? JF - The Holocene : an interdisciplinary journal focusing on recent environmental change N2 - This study examines the course and driving forces of recent vegetation change in the Mongolian steppe. A sediment core covering the last 55years from a small closed-basin lake in central Mongolia was analyzed for its multi-proxy record at annual resolution. Pollen analysis shows that highest abundances of planted Poaceae and highest vegetation diversity occurred during 1977-1992, reflecting agricultural development in the lake area. A decrease in diversity and an increase in Artemisia abundance after 1992 indicate enhanced vegetation degradation in recent times, most probably because of overgrazing and farmland abandonment. Human impact is the main factor for the vegetation degradation within the past decades as revealed by a series of redundancy analyses, while climate change and soil erosion play subordinate roles. High Pediastrum (a green algae) influx, high atomic total organic carbon/total nitrogen (TOC/TN) ratios, abundant coarse detrital grains, and the decrease of C-13(org) and N-15 since about 1977 but particularly after 1992 indicate that abundant terrestrial organic matter and nutrients were transported into the lake and caused lake eutrophication, presumably because of intensified land use. Thus, we infer that the transition to a market economy in Mongolia since the early 1990s not only caused dramatic vegetation degradation but also affected the lake ecosystem through anthropogenic changes in the catchment area. KW - central Mongolia KW - grain size KW - human impact KW - lake eutrophication KW - pollen KW - vegetation degradation Y1 - 2014 U6 - https://doi.org/10.1177/0959683614540958 SN - 0959-6836 SN - 1477-0911 VL - 24 IS - 10 SP - 1206 EP - 1215 PB - Sage Publ. CY - London ER -