TY  - JOUR
A1  - Katagiri, Yohei
A1  - Hasegawa, Junko
A1  - Fujikura, Ushio
A1  - Hoshino, Rina
A1  - Matsunaga, Sachihiro
A1  - Tsukaya, Hirokazu
T1  - The coordination of ploidy and cell size differs between cell layers in
leaves
JF  - Development : Company of Biologists
N2  - Growth and developmental processes are occasionally accompanied by multiple rounds of DNA replication, known as endoreduplication. Coordination between endoreduplication and cell size regulation often plays a crucial role in proper organogenesis and cell differentiation. Here, we report that the level of correlation between ploidy and cell volume is different in the outer and inner cell layers of leaves of Arabidopsis thaliana using a novel imaging technique. Although there is a well-known, strong correlation between ploidy and cell volume in pavement cells of the epidermis, this correlation was extremely weak in palisade mesophyll cells. Induction of epidermis cell identity based on the expression of the homeobox gene ATML1 in mesophyll cells enhanced the level of correlation between ploidy and cell volume to near that of wild-type epidermal cells. We therefore propose that the correlation between ploidy and cell volume is regulated by cell identity.
KW  - Endoreduplication
KW  - Ploidy
KW  - Cell volume
KW  - Mesophyll tissue
KW  - Epidermis
KW  - ATML1
Y1  - 2016
U6  - https://doi.org/10.1242/dev.130021
SN  - 0950-1991
SN  - 1477-9129
VL  - 143
SP  - 1120
EP  - 1125
PB  - Company of Biologists Limited
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Tsukaya, Hirokazu
A1  - Byrne, Mary E.
A1  - Horiguchi, Gorou
A1  - Sugiyama, Munetaka
A1  - Van Lijsebettens, Mieke
A1  - Lenhard, Michael
T1  - How do 'housekeeping' genes control organogenesis?-unexpected new findings on the role of housekeeping genes in cell and organ differentiation
JF  - Journal of plant research
N2  - In recent years, an increasing number of mutations in what would appear to be 'housekeeping genes' have been identified as having unexpectedly specific defects in multicellular organogenesis. This is also the case for organogenesis in seed plants. Although it is not surprising that loss-of-function mutations in 'housekeeping' genes result in lethality or growth retardation, it is surprising when (1) the mutant phenotype results from the loss of function of a 'housekeeping' gene and (2) the mutant phenotype is specific. In this review, by defining housekeeping genes as those encoding proteins that work in basic metabolic and cellular functions, we discuss unexpected links between housekeeping genes and specific developmental processes. In a surprising number of cases housekeeping genes coding for enzymes or proteins with functions in basic cellular processes such as transcription, post-transcriptional modification, and translation affect plant development.
KW  - Development
KW  - Housekeeping genes
KW  - Post-transcriptional modification
KW  - RNAPII
KW  - Pre-mRNA splicing
KW  - Ribosome
KW  - 3 '-end processing
KW  - Transcription
KW  - Translation
Y1  - 2013
U6  - https://doi.org/10.1007/s10265-012-0518-2
SN  - 0918-9440
VL  - 126
IS  - 1
SP  - 3
EP  - 15
PB  - Springer
CY  - Tokyo
ER  -