TY  - JOUR
A1  - Kiefer, Thomas
A1  - Krahl, Dorothea
A1  - Osthoff, Kathrin
A1  - Thuss-Patience, Peter
A1  - Bunse, Jörg
A1  - Adam, Ulrich
A1  - Jansen, Marc H.
A1  - Ott, Rudolf
A1  - Pfitzmann, Robert
A1  - Pross, Matthias
A1  - Kohlmann, Thomas
A1  - Daeschlein, Georg
A1  - Buhlert, Hermann
A1  - Völler, Heinz
A1  - Hirt, Carsten
T1  - Importance of Pancreatic Enzyme Replacement Therapy after Surgery of Cancer of the Esophagus or the Esophagogastric Junction
JF  - Nutrition and cancer : an international journal
N2  - After surgical treatment of cancer of the esophagus or the esophagogastric junction we observed steatorrhea, which is so far seldom reported. We analyzed all patients treated in our rehabilitation clinic between 2011 and 2014 and focused on the impact of surgery on digestion of fat. Reported steatorrhea was anamnestic, no pancreatic function test was made. Here we show the results from 51 patients. Twenty-three (45%) of the patients reported steatorrhea. Assuming decreased pancreatic function pancreatic enzyme replacement therapy (PERT) was started or modified during the rehabilitation stay (in the following called STEA(+)). These patients were compared with the patients without steatorrhea and without PERT (STEA(-)). Maximum weight loss between surgery and rehabilitation start was 18 kg in STEA(+) patient and 15.3 kg in STEA(-) patients. STEA(+) patients gained more weight under PERT during the rehabilitation phase (3 wk) than STEA(-) patients without PERT (+1.0 kg vs. -0.3 kg, P = 0.032). We report for the first time, that patients after cancer related esophageal surgery show anamnestic signs of exocrine pancreas insufficiency and need PERT to gain body weight.
Y1  - 2017
U6  - https://doi.org/10.1080/01635581.2017.1374419
SN  - 0163-5581
SN  - 1532-7914
VL  - 70
IS  - 1
SP  - 69
EP  - 72
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Wick, Kristin
A1  - Leeger-Aschmann, Claudia S.
A1  - Monn, Nico D.
A1  - Radtke, Thomas
A1  - Ott, Laura V.
A1  - Rebholz, Cornelia E.
A1  - Cruz, Sergio
A1  - Gerber, Natalie
A1  - Schmutz, Einat A.
A1  - Puder, Jardena J.
A1  - Munsch, Simone
A1  - Kakebeeke, Tanja H.
A1  - Jenni, Oskar G.
A1  - Granacher, Urs
A1  - Kriemler, Susi
T1  - Interventions to Promote Fundamental Movement Skills in Childcare and Kindergarten: A Systematic Review and Meta-Analysis
JF  - Sports medicine
N2  - Background Proficiency in fundamental movement skills (FMS) lays the foundation for being physically active and developing more complex motor skills. Improving these motor skills may provide enhanced opportunities for the development of a variety of perceptual, social, and cognitive skills. Objective The objective of this systematic review and meta-analysis was to assess the effects of FMS interventions on actual FMS, targeting typically developing young children. Method Searches in seven databases (CINAHL, Embase, MEDLINE, PsycINFO, PubMed, Scopus, Web of Science) up to August 2015 were completed. Trials with children (aged 2-6 years) in childcare or kindergarten settings that applied FMS-enhancing intervention programs of at least 4 weeks and meeting the inclusion criteria were included. Standardized data extraction forms were used. Risk of bias was assessed using a standard scoring scheme (Effective Public Health Practice Project-Quality Assessment Tool for Quantitative Studies [EPHPP]). We calculated effects on overall FMS, object control and locomotor subscales (OCS and LMS) by weighted standardized mean differences (SMDbetween) using random-effects models. Certainty in training effects was evaluated using GRADE (Grading of Recommendations Assessment, Development, and Evaluation System). Results Thirty trials (15 randomized controlled trials and 15 controlled trials) involving 6126 preschoolers (aged 3.3-5.5 years) revealed significant differences among groups in favor of the intervention group (INT) with small-to-large effects on overall FMS (SMDbetween 0.46), OCS (SMDbetween 1.36), and LMS (SMDbetween 0.94). Our certainty in the treatment estimates based on GRADE is very low. Conclusions Although there is relevant effectiveness of programs to improve FMS proficiency in healthy young children, they need to be interpreted with care as they are based on low-quality evidence and immediate post-intervention effects without long-term follow-up.
Y1  - 2017
U6  - https://doi.org/10.1007/s40279-017-0723-1
SN  - 0112-1642
SN  - 1179-2035
VL  - 47
SP  - 2045
EP  - 2068
PB  - Springer
CY  - Northcote
ER  -