TY  - JOUR
A1  - Taal, H. Rob
A1  - St Pourcain, Beate
A1  - Thiering, Elisabeth
A1  - Das, Shikta
A1  - Mook-Kanamori, Dennis O.
A1  - Warrington, Nicole M.
A1  - Kaakinen, Marika
A1  - Kreiner-Moller, Eskil
A1  - Bradfield, Jonathan P.
A1  - Freathy, Rachel M.
A1  - Geller, Frank
A1  - Guxens, Monica
A1  - Cousminer, Diana L.
A1  - Kerkhof, Marjan
A1  - Timpson, Nicholas J.
A1  - Ikram, M. Arfan
A1  - Beilin, Lawrence J.
A1  - Bonnelykke, Klaus
A1  - Buxton, Jessica L.
A1  - Charoen, Pimphen
A1  - Chawes, Bo Lund Krogsgaard
A1  - Eriksson, Johan
A1  - Evans, David M.
A1  - Hofman, Albert
A1  - Kemp, John P.
A1  - Kim, Cecilia E.
A1  - Klopp, Norman
A1  - Lahti, Jari
A1  - Lye, Stephen J.
A1  - McMahon, George
A1  - Mentch, Frank D.
A1  - Mueller-Nurasyid, Martina
A1  - O'Reilly, Paul F.
A1  - Prokopenko, Inga
A1  - Rivadeneira, Fernando
A1  - Steegers, Eric A. P.
A1  - Sunyer, Jordi
A1  - Tiesler, Carla
A1  - Yaghootkar, Hanieh
A1  - Breteler, Monique M. B.
A1  - Debette, Stephanie
A1  - Fornage, Myriam
A1  - Gudnason, Vilmundur
A1  - Launer, Lenore J.
A1  - van der Lugt, Aad
A1  - Mosley, Thomas H.
A1  - Seshadri, Sudha
A1  - Smith, Albert V.
A1  - Vernooij, Meike W.
A1  - Blakemore, Alexandra I. F.
A1  - Chiavacci, Rosetta M.
A1  - Feenstra, Bjarke
A1  - Fernandez-Banet, Julio
A1  - Grant, Struan F. A.
A1  - Hartikainen, Anna-Liisa
A1  - van der Heijden, Albert J.
A1  - Iniguez, Carmen
A1  - Lathrop, Mark
A1  - McArdle, Wendy L.
A1  - Molgaard, Anne
A1  - Newnham, John P.
A1  - Palmer, Lyle J.
A1  - Palotie, Aarno
A1  - Pouta, Annneli
A1  - Ring, Susan M.
A1  - Sovio, Ulla
A1  - Standl, Marie
A1  - Uitterlinden, Andre G.
A1  - Wichmann, H-Erich
A1  - Vissing, Nadja Hawwa
A1  - DeCarli, Charles
A1  - van Duijn, Cornelia M.
A1  - McCarthy, Mark I.
A1  - Koppelman, Gerard H.
A1  - Estivill, Xavier
A1  - Hattersley, Andrew T.
A1  - Melbye, Mads
A1  - Bisgaard, Hans
A1  - Pennell, Craig E.
A1  - Widen, Elisabeth
A1  - Hakonarson, Hakon
A1  - Smith, George Davey
A1  - Heinrich, Joachim
A1  - Jarvelin, Marjo-Riitta
A1  - Jaddoe, Vincent W. V.
A1  - Adair, Linda S.
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - van Beijsterveldt, Toos
A1  - Bergen, Nienke
A1  - Benke, Kelly
A1  - Berry, Diane J.
A1  - Bradfield, Jonathan P.
A1  - Charoen, Pimphen
A1  - Coin, Lachlan
A1  - Cousminer, Diana L.
A1  - Das, Shikta
A1  - Davis, Oliver S. P.
A1  - Elliott, Paul
A1  - Evans, David M.
A1  - Feenstra, Bjarke
A1  - Flexeder, Claudia
A1  - Frayling, Tim
A1  - Freathy, Rachel M.
A1  - Gaillard, Romy
A1  - Geller, Frank
A1  - Groen-Blokhuis, Maria
A1  - Goh, Liang-Kee
A1  - Guxens, Monica
A1  - Haworth, Claire M. A.
A1  - Hadley, Dexter
A1  - Hebebrand, Johannes
A1  - Hinney, Anke
A1  - Hirschhorn, Joel N.
A1  - Holloway, John W.
A1  - Holst, Claus
A1  - Hottenga, Jouke Jan
A1  - Horikoshi, Momoko
A1  - Huikari, Ville
A1  - Hypponen, Elina
A1  - Iniguez, Carmen
A1  - Kaakinen, Marika
A1  - Kilpelainen, Tuomas O.
A1  - Kirin, Mirna
A1  - Kowgier, Matthew
A1  - Lakka, Hanna-Maaria
A1  - Lange, Leslie A.
A1  - Lawlor, Debbie A.
A1  - Lehtimaki, Terho
A1  - Lewin, Alex
A1  - Lindgren, Cecilia
A1  - Lindi, Virpi
A1  - Maggi, Reedik
A1  - Marsh, Julie
A1  - Middeldorp, Christel
A1  - Millwood, Iona
A1  - Mook-Kanamori, Dennis O.
A1  - Murray, Jeffrey C.
A1  - Nivard, Michel
A1  - Nohr, Ellen Aagaard
A1  - Ntalla, Ioanna
A1  - Oken, Emily
A1  - O'Reilly, Paul F.
A1  - Palmer, Lyle J.
A1  - Panoutsopoulou, Kalliope
A1  - Pararajasingham, Jennifer
A1  - Prokopenko, Inga
A1  - Rodriguez, Alina
A1  - Salem, Rany M.
A1  - Sebert, Sylvain
A1  - Siitonen, Niina
A1  - Sovio, Ulla
A1  - St Pourcain, Beate
A1  - Strachan, David P.
A1  - Sunyer, Jordi
A1  - Taal, H. Rob
A1  - Teo, Yik-Ying
A1  - Thiering, Elisabeth
A1  - Tiesler, Carla
A1  - Uitterlinden, Andre G.
A1  - Valcarcel, Beatriz
A1  - Warrington, Nicole M.
A1  - White, Scott
A1  - Willemsen, Gonneke
A1  - Yaghootkar, Hanieh
A1  - Zeggini, Eleftheria
A1  - Boomsma, Dorret I.
A1  - Cooper, Cyrus
A1  - Estivill, Xavier
A1  - Gillman, Matthew
A1  - Grant, Struan F. A.
A1  - Hakonarson, Hakon
A1  - Hattersley, Andrew T.
A1  - Heinrich, Joachim
A1  - Hocher, Berthold
A1  - Jaddoe, Vincent W. V.
A1  - Jarvelin, Marjo-Riitta
A1  - Lakka, Timo A.
A1  - McCarthy, Mark I.
A1  - Melbye, Mads
A1  - Mohlke, Karen L.
A1  - Dedoussis, George V.
A1  - Ong, Ken K.
A1  - Pearson, Ewan R.
A1  - Pennell, Craig E.
A1  - Price, Thomas S.
A1  - Power, Chris
A1  - Raitakari, Olli T.
A1  - Saw, Seang-Mei
A1  - Scherag, Andre
A1  - Simell, Olli
A1  - Sorensen, Thorkild I. A.
A1  - Timpson, Nicholas J.
A1  - Widen, Elisabeth
A1  - Wilson, James F.
A1  - Ang, Wei
A1  - van Beijsterveldt, Toos
A1  - Bergen, Nienke
A1  - Benke, Kelly
A1  - Berry, Diane J.
A1  - Bradfield, Jonathan P.
A1  - Charoen, Pimphen
A1  - Coin, Lachlan
A1  - Cousminer, Diana L.
A1  - Das, Shikta
A1  - Elliott, Paul
A1  - Evans, David M.
A1  - Frayling, Tim
A1  - Freathy, Rachel M.
A1  - Gaillard, Romy
A1  - Groen-Blokhuis, Maria
A1  - Guxens, Monica
A1  - Hadley, Dexter
A1  - Hottenga, Jouke Jan
A1  - Huikari, Ville
A1  - Hypponen, Elina
A1  - Kaakinen, Marika
A1  - Kowgier, Matthew
A1  - Lawlor, Debbie A.
A1  - Lewin, Alex
A1  - Lindgren, Cecilia
A1  - Marsh, Julie
A1  - Middeldorp, Christel
A1  - Millwood, Iona
A1  - Mook-Kanamori, Dennis O.
A1  - Nivard, Michel
A1  - O'Reilly, Paul F.
A1  - Palmer, Lyle J.
A1  - Prokopenko, Inga
A1  - Rodriguez, Alina
A1  - Sebert, Sylvain
A1  - Sovio, Ulla
A1  - St Pourcain, Beate
A1  - Standl, Marie
A1  - Strachan, David P.
A1  - Sunyer, Jordi
A1  - Taal, H. Rob
A1  - Thiering, Elisabeth
A1  - Tiesler, Carla
A1  - Uitterlinden, Andre G.
A1  - Valcarcel, Beatriz
A1  - Warrington, Nicole M.
A1  - White, Scott
A1  - Willemsen, Gonneke
A1  - Yaghootkar, Hanieh
A1  - Boomsma, Dorret I.
A1  - Estivill, Xavier
A1  - Grant, Struan F. A.
A1  - Hakonarson, Hakon
A1  - Hattersley, Andrew T.
A1  - Heinrich, Joachim
A1  - Jaddoe, Vincent W. V.
A1  - Jarvelin, Marjo-Riitta
A1  - McCarthy, Mark I.
A1  - Pennell, Craig E.
A1  - Power, Chris
A1  - Timpson, Nicholas J.
A1  - Widen, Elisabeth
A1  - Ikram, M. Arfan
A1  - Fornage, Myriam
A1  - Smith, Albert V.
A1  - Seshadri, Sudha
A1  - Schmidt, Reinhold
A1  - Debette, Stephanie
A1  - Vrooman, Henri A.
A1  - Sigurdsson, Sigurdur
A1  - Ropele, Stefan
A1  - Coker, Laura H.
A1  - Longstreth, W. T.
A1  - Niessen, Wiro J.
A1  - DeStefano, Anita L.
A1  - Beiser, Alexa
A1  - Zijdenbos, Alex P.
A1  - Struchalin, Maksim
A1  - Jack, Clifford R.
A1  - Nalls, Mike A.
A1  - Au, Rhoda
A1  - Hofman, Albert
A1  - Gudnason, Haukur
A1  - van der Lugt, Aad
A1  - Harris, Tamara B.
A1  - Meeks, William M.
A1  - Vernooij, Meike W.
A1  - van Buchem, Mark A.
A1  - Catellier, Diane
A1  - Gudnason, Vilmundur
A1  - Windham, B. Gwen
A1  - Wolf, Philip A.
A1  - van Duijn, Cornelia M.
A1  - Mosley, Thomas H.
A1  - Schmidt, Helena
A1  - Launer, Lenore J.
A1  - Breteler, Monique M. B.
A1  - DeCarli, Charles
T1  - Common variants at 12q15 and 12q24 are associated with infant head circumference
JF  - Nature genetics
N2  - To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.
Y1  - 2012
U6  - https://doi.org/10.1038/ng.2238
SN  - 1061-4036
VL  - 44
IS  - 5
SP  - 532
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Wuttke, Matthias
A1  - Li, Yong
A1  - Li, Man
A1  - Sieber, Karsten B.
A1  - Feitosa, Mary F.
A1  - Gorski, Mathias
A1  - Tin, Adrienne
A1  - Wang, Lihua
A1  - Chu, Audrey Y.
A1  - Hoppmann, Anselm
A1  - Kirsten, Holger
A1  - Giri, Ayush
A1  - Chai, Jin-Fang
A1  - Sveinbjornsson, Gardar
A1  - Tayo, Bamidele O.
A1  - Nutile, Teresa
A1  - Fuchsberger, Christian
A1  - Marten, Jonathan
A1  - Cocca, Massimiliano
A1  - Ghasemi, Sahar
A1  - Xu, Yizhe
A1  - Horn, Katrin
A1  - Noce, Damia
A1  - Van der Most, Peter J.
A1  - Sedaghat, Sanaz
A1  - Yu, Zhi
A1  - Akiyama, Masato
A1  - Afaq, Saima
A1  - Ahluwalia, Tarunveer Singh
A1  - Almgren, Peter
A1  - Amin, Najaf
A1  - Arnlov, Johan
A1  - Bakker, Stephan J. L.
A1  - Bansal, Nisha
A1  - Baptista, Daniela
A1  - Bergmann, Sven
A1  - Biggs, Mary L.
A1  - Biino, Ginevra
A1  - Boehnke, Michael
A1  - Boerwinkle, Eric
A1  - Boissel, Mathilde
A1  - Böttinger, Erwin
A1  - Boutin, Thibaud S.
A1  - Brenner, Hermann
A1  - Brumat, Marco
A1  - Burkhardt, Ralph
A1  - Butterworth, Adam S.
A1  - Campana, Eric
A1  - Campbell, Archie
A1  - Campbell, Harry
A1  - Canouil, Mickael
A1  - Carroll, Robert J.
A1  - Catamo, Eulalia
A1  - Chambers, John C.
A1  - Chee, Miao-Ling
A1  - Chee, Miao-Li
A1  - Chen, Xu
A1  - Cheng, Ching-Yu
A1  - Cheng, Yurong
A1  - Christensen, Kaare
A1  - Cifkova, Renata
A1  - Ciullo, Marina
A1  - Concas, Maria Pina
A1  - Cook, James P.
A1  - Coresh, Josef
A1  - Corre, Tanguy
A1  - Sala, Cinzia Felicita
A1  - Cusi, Daniele
A1  - Danesh, John
A1  - Daw, E. Warwick
A1  - De Borst, Martin H.
A1  - De Grandi, Alessandro
A1  - De Mutsert, Renee
A1  - De Vries, Aiko P. J.
A1  - Degenhardt, Frauke
A1  - Delgado, Graciela
A1  - Demirkan, Ayse
A1  - Di Angelantonio, Emanuele
A1  - Dittrich, Katalin
A1  - Divers, Jasmin
A1  - Dorajoo, Rajkumar
A1  - Eckardt, Kai-Uwe
A1  - Ehret, Georg
A1  - Elliott, Paul
A1  - Endlich, Karlhans
A1  - Evans, Michele K.
A1  - Felix, Janine F.
A1  - Foo, Valencia Hui Xian
A1  - Franco, Oscar H.
A1  - Franke, Andre
A1  - Freedman, Barry I.
A1  - Freitag-Wolf, Sandra
A1  - Friedlander, Yechiel
A1  - Froguel, Philippe
A1  - Gansevoort, Ron T.
A1  - Gao, He
A1  - Gasparini, Paolo
A1  - Gaziano, J. Michael
A1  - Giedraitis, Vilmantas
A1  - Gieger, Christian
A1  - Girotto, Giorgia
A1  - Giulianini, Franco
A1  - Gogele, Martin
A1  - Gordon, Scott D.
A1  - Gudbjartsson, Daniel F.
A1  - Gudnason, Vilmundur
A1  - Haller, Toomas
A1  - Hamet, Pavel
A1  - Harris, Tamara B.
A1  - Hartman, Catharina A.
A1  - Hayward, Caroline
A1  - Hellwege, Jacklyn N.
A1  - Heng, Chew-Kiat
A1  - Hicks, Andrew A.
A1  - Hofer, Edith
A1  - Huang, Wei
A1  - Hutri-Kahonen, Nina
A1  - Hwang, Shih-Jen
A1  - Ikram, M. Arfan
A1  - Indridason, Olafur S.
A1  - Ingelsson, Erik
A1  - Ising, Marcus
A1  - Jaddoe, Vincent W. V.
A1  - Jakobsdottir, Johanna
A1  - Jonas, Jost B.
A1  - Joshi, Peter K.
A1  - Josyula, Navya Shilpa
A1  - Jung, Bettina
A1  - Kahonen, Mika
A1  - Kamatani, Yoichiro
A1  - Kammerer, Candace M.
A1  - Kanai, Masahiro
A1  - Kastarinen, Mika
A1  - Kerr, Shona M.
A1  - Khor, Chiea-Chuen
A1  - Kiess, Wieland
A1  - Kleber, Marcus E.
A1  - Koenig, Wolfgang
A1  - Kooner, Jaspal S.
A1  - Korner, Antje
A1  - Kovacs, Peter
A1  - Kraja, Aldi T.
A1  - Krajcoviechova, Alena
A1  - Kramer, Holly
A1  - Kramer, Bernhard K.
A1  - Kronenberg, Florian
A1  - Kubo, Michiaki
A1  - Kuhnel, Brigitte
A1  - Kuokkanen, Mikko
A1  - Kuusisto, Johanna
A1  - La Bianca, Martina
A1  - Laakso, Markku
A1  - Lange, Leslie A.
A1  - Langefeld, Carl D.
A1  - Lee, Jeannette Jen-Mai
A1  - Lehne, Benjamin
A1  - Lehtimaki, Terho
A1  - Lieb, Wolfgang
A1  - Lim, Su-Chi
A1  - Lind, Lars
A1  - Lindgren, Cecilia M.
A1  - Liu, Jun
A1  - Liu, Jianjun
A1  - Loeffler, Markus
A1  - Loos, Ruth J. F.
A1  - Lucae, Susanne
A1  - Lukas, Mary Ann
A1  - Lyytikainen, Leo-Pekka
A1  - Magi, Reedik
A1  - Magnusson, Patrik K. E.
A1  - Mahajan, Anubha
A1  - Martin, Nicholas G.
A1  - Martins, Jade
A1  - Marz, Winfried
A1  - Mascalzoni, Deborah
A1  - Matsuda, Koichi
A1  - Meisinger, Christa
A1  - Meitinger, Thomas
A1  - Melander, Olle
A1  - Metspalu, Andres
A1  - Mikaelsdottir, Evgenia K.
A1  - Milaneschi, Yuri
A1  - Miliku, Kozeta
A1  - Mishra, Pashupati P.
A1  - Program, V. A. Million Veteran
A1  - Mohlke, Karen L.
A1  - Mononen, Nina
A1  - Montgomery, Grant W.
A1  - Mook-Kanamori, Dennis O.
A1  - Mychaleckyj, Josyf C.
A1  - Nadkarni, Girish N.
A1  - Nalls, Mike A.
A1  - Nauck, Matthias
A1  - Nikus, Kjell
A1  - Ning, Boting
A1  - Nolte, Ilja M.
A1  - Noordam, Raymond
A1  - Olafsson, Isleifur
A1  - Oldehinkel, Albertine J.
A1  - Orho-Melander, Marju
A1  - Ouwehand, Willem H.
A1  - Padmanabhan, Sandosh
A1  - Palmer, Nicholette D.
A1  - Palsson, Runolfur
A1  - Penninx, Brenda W. J. H.
A1  - Perls, Thomas
A1  - Perola, Markus
A1  - Pirastu, Mario
A1  - Pirastu, Nicola
A1  - Pistis, Giorgio
A1  - Podgornaia, Anna I.
A1  - Polasek, Ozren
A1  - Ponte, Belen
A1  - Porteous, David J.
A1  - Poulain, Tanja
A1  - Pramstaller, Peter P.
A1  - Preuss, Michael H.
A1  - Prins, Bram P.
A1  - Province, Michael A.
A1  - Rabelink, Ton J.
A1  - Raffield, Laura M.
A1  - Raitakari, Olli T.
A1  - Reilly, Dermot F.
A1  - Rettig, Rainer
A1  - Rheinberger, Myriam
A1  - Rice, Kenneth M.
A1  - Ridker, Paul M.
A1  - Rivadeneira, Fernando
A1  - Rizzi, Federica
A1  - Roberts, David J.
A1  - Robino, Antonietta
A1  - Rossing, Peter
A1  - Rudan, Igor
A1  - Rueedi, Rico
A1  - Ruggiero, Daniela
A1  - Ryan, Kathleen A.
A1  - Saba, Yasaman
A1  - Sabanayagam, Charumathi
A1  - Salomaa, Veikko
A1  - Salvi, Erika
A1  - Saum, Kai-Uwe
A1  - Schmidt, Helena
A1  - Schmidt, Reinhold
A1  - Ben Schottker, 
A1  - Schulz, Christina-Alexandra
A1  - Schupf, Nicole
A1  - Shaffer, Christian M.
A1  - Shi, Yuan
A1  - Smith, Albert V.
A1  - Smith, Blair H.
A1  - Soranzo, Nicole
A1  - Spracklen, Cassandra N.
A1  - Strauch, Konstantin
A1  - Stringham, Heather M.
A1  - Stumvoll, Michael
A1  - Svensson, Per O.
A1  - Szymczak, Silke
A1  - Tai, E-Shyong
A1  - Tajuddin, Salman M.
A1  - Tan, Nicholas Y. Q.
A1  - Taylor, Kent D.
A1  - Teren, Andrej
A1  - Tham, Yih-Chung
A1  - Thiery, Joachim
A1  - Thio, Chris H. L.
A1  - Thomsen, Hauke
A1  - Thorleifsson, Gudmar
A1  - Toniolo, Daniela
A1  - Tonjes, Anke
A1  - Tremblay, Johanne
A1  - Tzoulaki, Ioanna
A1  - Uitterlinden, Andre G.
A1  - Vaccargiu, Simona
A1  - Van Dam, Rob M.
A1  - Van der Harst, Pim
A1  - Van Duijn, Cornelia M.
A1  - Edward, Digna R. Velez
A1  - Verweij, Niek
A1  - Vogelezang, Suzanne
A1  - Volker, Uwe
A1  - Vollenweider, Peter
A1  - Waeber, Gerard
A1  - Waldenberger, Melanie
A1  - Wallentin, Lars
A1  - Wang, Ya Xing
A1  - Wang, Chaolong
A1  - Waterworth, Dawn M.
A1  - Bin Wei, Wen
A1  - White, Harvey
A1  - Whitfield, John B.
A1  - Wild, Sarah H.
A1  - Wilson, James F.
A1  - Wojczynski, Mary K.
A1  - Wong, Charlene
A1  - Wong, Tien-Yin
A1  - Xu, Liang
A1  - Yang, Qiong
A1  - Yasuda, Masayuki
A1  - Yerges-Armstrong, Laura M.
A1  - Zhang, Weihua
A1  - Zonderman, Alan B.
A1  - Rotter, Jerome I.
A1  - Bochud, Murielle
A1  - Psaty, Bruce M.
A1  - Vitart, Veronique
A1  - Wilson, James G.
A1  - Dehghan, Abbas
A1  - Parsa, Afshin
A1  - Chasman, Daniel I.
A1  - Ho, Kevin
A1  - Morris, Andrew P.
A1  - Devuyst, Olivier
A1  - Akilesh, Shreeram
A1  - Pendergrass, Sarah A.
A1  - Sim, Xueling
A1  - Boger, Carsten A.
A1  - Okada, Yukinori
A1  - Edwards, Todd L.
A1  - Snieder, Harold
A1  - Stefansson, Kari
A1  - Hung, Adriana M.
A1  - Heid, Iris M.
A1  - Scholz, Markus
A1  - Teumer, Alexander
A1  - Kottgen, Anna
A1  - Pattaro, Cristian
T1  - A catalog of genetic loci associated with kidney function from analyses of a million individuals
JF  - Nature genetics
N2  - Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.
Y1  - 2019
U6  - https://doi.org/10.1038/s41588-019-0407-x
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 6
SP  - 957
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - INPR
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A1  - Zech, Alraune
A1  - Zhao, A.
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A1  - Zietara, K.
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T1  - Introducing the CTA concept
T2  - Astroparticle physics
N2  - The Cherenkov Telescope Array (CTA) is a new observatory for very high-energy (VHE) gamma rays. CTA has ambitions science goals, for which it is necessary to achieve full-sky coverage, to improve the sensitivity by about an order of magnitude, to span about four decades of energy, from a few tens of GeV to above 100 TeV with enhanced angular and energy resolutions over existing VHE gamma-ray observatories. An international collaboration has formed with more than 1000 members from 27 countries in Europe, Asia, Africa and North and South America. In 2010 the CTA Consortium completed a Design Study and started a three-year Preparatory Phase which leads to production readiness of CTA in 2014. In this paper we introduce the science goals and the concept of CTA, and provide an overview of the project.
KW  - TeV gamma-ray astronomy
KW  - Air showers
KW  - Cherenkov Telescopes
Y1  - 2013
U6  - https://doi.org/10.1016/j.astropartphys.2013.01.007
SN  - 0927-6505
SN  - 1873-2852
VL  - 43
IS  - 2
SP  - 3
EP  - 18
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
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A1  - Blanch Bigas, O.
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A1  - Lavalley, C.
A1  - Le Flour, T.
A1  - Le Padellec, A.
A1  - Lenain, J. -P.
A1  - Lessio, L.
A1  - Lieunard, B.
A1  - Lindfors, E.
A1  - Liolios, A.
A1  - Lohse, T.
A1  - Lombardi, S.
A1  - Lopatin, A.
A1  - Lorenz, E.
A1  - Lubinski, P.
A1  - Luz, O.
A1  - Lyard, E.
A1  - Maccarone, M. C.
A1  - Maccarone, T.
A1  - Maier, G.
A1  - Majumdar, P.
A1  - Maltezos, S.
A1  - Malkiewicz, P.
A1  - Mana, C.
A1  - Manalaysay, A.
A1  - Maneva, G.
A1  - Mangano, A.
A1  - Manigot, P.
A1  - Marin, J.
A1  - Mariotti, M.
A1  - Markoff, S.
A1  - Martinez, G.
A1  - Martinez, M.
A1  - Mastichiadis, A.
A1  - Matsumoto, H.
A1  - Mattiazzo, S.
A1  - Mazin, D.
A1  - McComb, T. J. L.
A1  - McCubbin, N.
A1  - McHardy, I.
A1  - Medina, C.
A1  - Melkumyan, D.
A1  - Mendes, A.
A1  - Mertsch, P.
A1  - Meucci, M.
A1  - Michalowski, J.
A1  - Micolon, P.
A1  - Mineo, T.
A1  - Mirabal, N.
A1  - Mirabel, F.
A1  - Miranda, J. M.
A1  - Mirzoyan, R.
A1  - Mizuno, T.
A1  - Moal, B.
A1  - Moderski, R.
A1  - Molinari, E.
A1  - Monteiro, I.
A1  - Moralejo, A.
A1  - Morello, C.
A1  - Mori, K.
A1  - Motta, G.
A1  - Mottez, F.
A1  - Moulin, Emmanuel
A1  - Mukherjee, R.
A1  - Munar, P.
A1  - Muraishi, H.
A1  - Murase, K.
A1  - Murphy, A. Stj.
A1  - Nagataki, S.
A1  - Naito, T.
A1  - Nakamori, T.
A1  - Nakayama, K.
A1  - Naumann, C. L.
A1  - Naumann, D.
A1  - Nayman, P.
A1  - Nedbal, D.
A1  - Niedzwiecki, A.
A1  - Niemiec, J.
A1  - Nikolaidis, A.
A1  - Nishijima, K.
A1  - Nolan, S. J.
A1  - Nowak, N.
A1  - O'Brien, P. T.
A1  - Ochoa, I.
A1  - Ohira, Y.
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A1  - Ong, R. A.
A1  - Orito, R.
A1  - Orr, M.
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A1  - Otero, L.
A1  - Otte, A. N.
A1  - Ovcharov, E.
A1  - Oya, I.
A1  - Ozieblo, A.
A1  - Paiano, S.
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A1  - Paoletti, R.
A1  - Papyan, G.
A1  - Paredes, J. M.
A1  - Pareschi, G.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pedaletti, G.
A1  - Pepato, A.
A1  - Persic, M.
A1  - Petrucci, P. O.
A1  - Peyaud, B.
A1  - Piechocki, W.
A1  - Pita, S.
A1  - Pivato, G.
A1  - Platos, L.
A1  - Platzer, R.
A1  - Pogosyan, L.
A1  - Pohl, Martin
A1  - Pojmanski, G.
A1  - Ponz, J. D.
A1  - Potter, W.
A1  - Prandini, E.
A1  - Preece, R.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quel, E.
A1  - Quirrenbach, A.
A1  - Rajda, P.
A1  - Rando, R.
A1  - Rataj, M.
A1  - Raue, M.
A1  - Reimann, C.
A1  - Reimann, O.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Renner, S.
A1  - Reymond, J. -M.
A1  - Rhode, W.
A1  - Ribo, M.
A1  - Ribordy, M.
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A1  - Rieger, F.
A1  - Ringegni, P.
A1  - Ripken, J.
A1  - Ristori, P.
A1  - Rivoire, S.
A1  - Rob, L.
A1  - Rodriguez, S.
A1  - Roeser, U.
A1  - Romano, Patrizia
A1  - Romero, G. E.
A1  - Rosier-Lees, S.
A1  - Rovero, A. C.
A1  - Roy, F.
A1  - Royer, S.
A1  - Rudak, B.
A1  - Rulten, C. B.
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A1  - Russo, F.
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A1  - Saito, K.
A1  - Saito, T.
A1  - Sakaki, N.
A1  - Salazar, E.
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A1  - Sanchez Conde, M. A.
A1  - Santangelo, Andrea
A1  - Santos, E. M.
A1  - Sanuy, A.
A1  - Sapozhnikov, L.
A1  - Sarkar, S.
A1  - Scalzotto, V.
A1  - Scapin, V.
A1  - Scarcioffolo, M.
A1  - Schanz, T.
A1  - Schlenstedt, S.
A1  - Schlickeiser, R.
A1  - Schmidt, T.
A1  - Schmoll, J.
A1  - Schroedter, M.
A1  - Schultz, C.
A1  - Schultze, J.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schweizer, T.
A1  - Seiradakis, J.
A1  - Selmane, S.
A1  - Seweryn, K.
A1  - Shayduk, M.
A1  - Shellard, R. C.
A1  - Shibata, T.
A1  - Sikora, M.
A1  - Silk, J.
A1  - Sillanpaa, A.
A1  - Sitarek, J.
A1  - Skole, C.
A1  - Smith, N.
A1  - Sobczynska, D.
A1  - Sofo Haro, M.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Spiga, D.
A1  - Spyrou, S.
A1  - Stamatescu, V.
A1  - Stamerra, A.
A1  - Starling, R. L. C.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steiner, S.
A1  - Stergioulas, N.
A1  - Sternberger, R.
A1  - Stinzing, F.
A1  - Stodulski, M.
A1  - Straumann, U.
A1  - Suarez, A.
A1  - Suchenek, M.
A1  - Sugawara, R.
A1  - Sulanke, K. H.
A1  - Sun, S.
A1  - Supanitsky, A. D.
A1  - Sutcliffe, P.
A1  - Szanecki, M.
A1  - Szepieniec, T.
A1  - Szostek, A.
A1  - Szymkowiak, A.
A1  - Tagliaferri, G.
A1  - Tajima, H.
A1  - Takahashi, H.
A1  - Takahashi, K.
A1  - Takalo, L.
A1  - Takami, H.
A1  - Talbot, R. G.
A1  - Tam, P. H.
A1  - Tanaka, M.
A1  - Tanimori, T.
A1  - Tavani, M.
A1  - Tavernet, J. -P.
A1  - Tchernin, C.
A1  - Tejedor, L. A.
A1  - Telezhinsky, Igor O.
A1  - Temnikov, P.
A1  - Tenzer, C.
A1  - Terada, Y.
A1  - Terrier, R.
A1  - Teshima, M.
A1  - Testa, V.
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A1  - Tokarz, M.
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A1  - Vallania, P.
A1  - Vallejo, G.
A1  - van der Walt, J.
A1  - van Eldik, C.
A1  - Vandenbroucke, J.
A1  - Vankov, H.
A1  - Vasileiadis, G.
A1  - Vassiliev, V. V.
A1  - Vegas, I.
A1  - Venter, L.
A1  - Vercellone, S.
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A1  - Vogler, P.
A1  - Vollhardt, A.
A1  - Volpe, F.
A1  - Von Gunten, H. P.
A1  - Vorobiov, S.
A1  - Wagner, S.
A1  - Wagner, R. M.
A1  - Wagner, B.
A1  - Wakely, S. P.
A1  - Walter, P.
A1  - Walter, R.
A1  - Warwick, R.
A1  - Wawer, P.
A1  - Wawrzaszek, R.
A1  - Webb, N.
A1  - Wegner, P.
A1  - Weinstein, A.
A1  - Weitzel, Q.
A1  - Welsing, R.
A1  - Wetteskind, H.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wilkinson, M. I.
A1  - Williams, D. A.
A1  - Winde, M.
A1  - Wischnewski, R.
A1  - Wisniewski, L.
A1  - Wolczko, A.
A1  - Wood, M.
A1  - Xiong, Q.
A1  - Yamamoto, T.
A1  - Yamaoka, K.
A1  - Yamazaki, R.
A1  - Yanagita, S.
A1  - Yoffo, B.
A1  - Yonetani, M.
A1  - Yoshida, A.
A1  - Yoshida, T.
A1  - Yoshikoshi, T.
A1  - Zabalza, V.
A1  - Zagdanski, A.
A1  - Zajczyk, A.
A1  - Zdziarski, A.
A1  - Zech, Alraune
A1  - Zietara, K.
A1  - Ziolkowski, P.
A1  - Zitelli, V.
A1  - Zychowski, P.
T1  - Design concepts for the Cherenkov Telescope Array CTA an advanced facility for ground-based high-energy gamma-ray astronomy
JF  - Experimental astronomy : an international journal on astronomical instrumentation and data analysis
N2  - Ground-based gamma-ray astronomy has had a major breakthrough with the impressive results obtained using systems of imaging atmospheric Cherenkov telescopes. Ground-based gamma-ray astronomy has a huge potential in astrophysics, particle physics and cosmology. CTA is an international initiative to build the next generation instrument, with a factor of 5-10 improvement in sensitivity in the 100 GeV-10 TeV range and the extension to energies well below 100 GeV and above 100 TeV. CTA will consist of two arrays (one in the north, one in the south) for full sky coverage and will be operated as open observatory. The design of CTA is based on currently available technology. This document reports on the status and presents the major design concepts of CTA.
KW  - Ground based gamma ray astronomy
KW  - Next generation Cherenkov telescopes
KW  - Design concepts
Y1  - 2011
U6  - https://doi.org/10.1007/s10686-011-9247-0
SN  - 0922-6435
SN  - 1572-9508
VL  - 32
IS  - 3
SP  - 193
EP  - 316
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Ikram, M. Arfan
A1  - Fornage, Myriam
A1  - Smith, Albert V.
A1  - Seshadri, Sudha
A1  - Schmidt, Reinhold
A1  - Debette, Stephanie
A1  - Vrooman, Henri A.
A1  - Sigurdsson, Sigurdur
A1  - Ropele, Stefan
A1  - Taal, H. Rob
A1  - Mook-Kanamori, Dennis O.
A1  - Coker, Laura H.
A1  - Longstreth, W. T.
A1  - Niessen, Wiro J.
A1  - DeStefano, Anita L.
A1  - Beiser, Alexa
A1  - Zijdenbos, Alex P.
A1  - Struchalin, Maksim
A1  - Jack, Clifford R.
A1  - Rivadeneira, Fernando
A1  - Uitterlinden, Andre G.
A1  - Knopman, David S.
A1  - Hartikainen, Anna-Liisa
A1  - Pennell, Craig E.
A1  - Thiering, Elisabeth
A1  - Steegers, Eric A. P.
A1  - Hakonarson, Hakon
A1  - Heinrich, Joachim
A1  - Palmer, Lyle J.
A1  - Jarvelin, Marjo-Riitta
A1  - McCarthy, Mark I.
A1  - Grant, Struan F. A.
A1  - St Pourcain, Beate
A1  - Timpson, Nicholas J.
A1  - Smith, George Davey
A1  - Sovio, Ulla
A1  - Nalls, Mike A.
A1  - Au, Rhoda
A1  - Hofman, Albert
A1  - Gudnason, Haukur
A1  - van der Lugt, Aad
A1  - Harris, Tamara B.
A1  - Meeks, William M.
A1  - Vernooij, Meike W.
A1  - van Buchem, Mark A.
A1  - Catellier, Diane
A1  - Jaddoe, Vincent W. V.
A1  - Gudnason, Vilmundur
A1  - Windham, B. Gwen
A1  - Wolf, Philip A.
A1  - van Duijn, Cornelia M.
A1  - Mosley, Thomas H.
A1  - Schmidt, Helena
A1  - Launer, Lenore J.
A1  - Breteler, Monique M. B.
A1  - DeCarli, Charles
A1  - Adair, Linda S.
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - vanBeijsterveldt, Toos
A1  - Bergen, Nienke
A1  - Benke, Kelly
A1  - Berry, Diane J.
A1  - Coin, Lachlan
A1  - Davis, Oliver S. P.
A1  - Elliott, Paul
A1  - Flexeder, Claudia
A1  - Frayling, Tim
A1  - Gaillard, Romy
A1  - Groen-Blokhuis, Maria
A1  - Goh, Liang-Kee
A1  - Haworth, Claire M. A.
A1  - Hadley, Dexter
A1  - Hebebrand, Johannes
A1  - Hinney, Anke
A1  - Hirschhorn, Joel N.
A1  - Holloway, John W.
A1  - Holst, Claus
A1  - Hottenga, Jouke Jan
A1  - Horikoshi, Momoko
A1  - Huikari, Ville
A1  - Hypponen, Elina
A1  - Kilpelainen, Tuomas O.
A1  - Kirin, Mirna
A1  - Kowgier, Matthew
A1  - Lakka, Hanna-Maaria
A1  - Lange, Leslie A.
A1  - Lawlor, Debbie A.
A1  - Lehtimaki, Terho
A1  - Lewin, Alex
A1  - Lindgren, Cecilia
A1  - Lindi, Virpi
A1  - Maggi, Reedik
A1  - Marsh, Julie
A1  - Middeldorp, Christel
A1  - Millwood, Iona
A1  - Murray, Jeffrey C.
A1  - Nivard, Michel
A1  - Nohr, Ellen Aagaard
A1  - Ntalla, Ioanna
A1  - Oken, Emily
A1  - Panoutsopoulou, Kalliope
A1  - Pararajasingham, Jennifer
A1  - Rodriguez, Alina
A1  - Salem, Rany M.
A1  - Sebert, Sylvain
A1  - Siitonen, Niina
A1  - Strachan, David P.
A1  - Teo, Yik-Ying
A1  - Valcarcel, Beatriz
A1  - Willemsen, Gonneke
A1  - Zeggini, Eleftheria
A1  - Boomsma, Dorret I.
A1  - Cooper, Cyrus
A1  - Gillman, Matthew
A1  - Hocher, Berthold
A1  - Lakka, Timo A.
A1  - Mohlke, Karen L.
A1  - Dedoussis, George V.
A1  - Ong, Ken K.
A1  - Pearson, Ewan R.
A1  - Price, Thomas S.
A1  - Power, Chris
A1  - Raitakari, Olli T.
A1  - Saw, Seang-Mei
A1  - Scherag, Andre
A1  - Simell, Olli
A1  - Sorensen, Thorkild I. A.
A1  - Wilson, James F.
T1  - Common variants at 6q22 and 17q21 are associated with intracranial volume
JF  - Nature genetics
N2  - During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our genome-wide association study (GWAS) in 8,175 community-dwelling elderly persons did not reveal any associations at genome-wide significance (P < 5 x 10(-8)) for brain volume. In contrast, intracranial volume was significantly associated with two loci: rs4273712 (P = 3.4 x 10(-11)), a known height-associated locus on chromosome 6q22, and rs9915547 (P = 1.5 x 10(-12)), localized to the inversion on chromosome 17q21. We replicated the associations of these loci with intracranial volume in a separate sample of 1,752 elderly persons (P = 1.1 x 10(-3) for 6q22 and 1.2 x 10(-3) for 17q21). Furthermore, we also found suggestive associations of the 17q21 locus with head circumference in 10,768 children (mean age of 14.5 months). Our data identify two loci associated with head size, with the inversion at 17q21 also likely to be involved in attaining maximal brain size.
Y1  - 2012
U6  - https://doi.org/10.1038/ng.2245
SN  - 1061-4036
VL  - 44
IS  - 5
SP  - 539
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Martinez Gonzalez, M. J.
A1  - Pastor Yabar, A.
A1  - Lagg, A.
A1  - Asensio Ramos, A.
A1  - Collados Vera, M.
A1  - Solanki, S. K.
A1  - Balthasar, H.
A1  - Berkefeld, T.
A1  - Denker, Carsten
A1  - Doerr, H. P.
A1  - Feller, A.
A1  - Franz, M.
A1  - González Manrique, Sergio Javier
A1  - Hofmann, A.
A1  - Kneer, F.
A1  - Kuckein, Christoph
A1  - Louis, R.
A1  - von der Lühe, O.
A1  - Nicklas, H.
A1  - Orozco, D.
A1  - Rezaei, R.
A1  - Schlichenmaier, R.
A1  - Schmidt, D.
A1  - Schmidt, W.
A1  - Sigwarth, M.
A1  - Sobotka, M.
A1  - Soltau, D.
A1  - Staude, J.
A1  - Strassmeier, Klaus G.
A1  - Verma, Meetu
A1  - Waldman, T.
A1  - Volkmer, R.
T1  - Inference of magnetic fields in the very quiet Sun
JF  - Journal of geophysical research : Earth surface
N2  - Context. Over the past 20 yr, the quietest areas of the solar surface have revealed a weak but extremely dynamic magnetism occurring at small scales (<500 km), which may provide an important contribution to the dynamics and energetics of the outer layers of the atmosphere. Understanding this magnetism requires the inference of physical quantities from high-sensitivity spectro-polarimetric data with high spatio-temporal resolution. Aims. We present high-precision spectro-polarimetric data with high spatial resolution (0.4") of the very quiet Sun at 1.56 mu m obtained with the GREGOR telescope to shed some light on this complex magnetism. Methods. We used inversion techniques in two main approaches. First, we assumed that the observed profiles can be reproduced with a constant magnetic field atmosphere embedded in a field-free medium. Second, we assumed that the resolution element has a substructure with either two constant magnetic atmospheres or a single magnetic atmosphere with gradients of the physical quantities along the optical depth, both coexisting with a global stray-light component. Results. Half of our observed quiet-Sun region is better explained by magnetic substructure within the resolution element. However, we cannot distinguish whether this substructure comes from gradients of the physical parameters along the line of sight or from horizontal gradients (across the surface). In these pixels, a model with two magnetic components is preferred, and we find two distinct magnetic field populations. The population with the larger filling factor has very weak (similar to 150 G) horizontal fields similar to those obtained in previous works. We demonstrate that the field vector of this population is not constrained by the observations, given the spatial resolution and polarimetric accuracy of our data. The topology of the other component with the smaller filling factor is constrained by the observations for field strengths above 250 G: we infer hG fields with inclinations and azimuth values compatible with an isotropic distribution. The filling factors are typically below 30%. We also find that the flux of the two polarities is not balanced. From the other half of the observed quiet-Sun area similar to 50% are two-lobed Stokes V profiles, meaning that 23% of the field of view can be adequately explained with a single constant magnetic field embedded in a non-magnetic atmosphere. The magnetic field vector and filling factor are reliable inferred in only 50% based on the regular profiles. Therefore, 12% of the field of view harbour hG fields with filling factors typically below 30%. At our present spatial resolution, 70% of the pixels apparently are non-magnetised.
KW  - Sun: atmosphere
KW  - Sun: magnetic fields
KW  - techniques: polarimetric
KW  - methods: observational
Y1  - 2016
U6  - https://doi.org/10.1051/0004-6361/201628449
SN  - 1432-0746
VL  - 596
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Verma, Meetu
A1  - Denker, Carsten
A1  - Balthasar, H.
A1  - Kuckein, Christoph
A1  - González Manrique, Sergio Javier
A1  - Sobotka, M.
A1  - Gonzalez, N. Bello
A1  - Hoch, S.
A1  - Diercke, Andrea
A1  - Kummerow, Philipp
A1  - Berkefeld, T.
A1  - Collados Vera, M.
A1  - Feller, A.
A1  - Hofmann, A.
A1  - Kneer, F.
A1  - Lagg, A.
A1  - Löhner-Böttcher, J.
A1  - Nicklas, H.
A1  - Pastor Yabar, A.
A1  - Schlichenmaier, R.
A1  - Schmidt, D.
A1  - Schmidt, W.
A1  - Schubert, M.
A1  - Sigwarth, M.
A1  - Solanki, S. K.
A1  - Soltau, D.
A1  - Staude, J.
A1  - Strassmeier, Klaus G.
A1  - Volkmer, R.
A1  - von der Lühe, O.
A1  - Waldmann, T.
T1  - Horizontal flow fields in and around a small active region The transition period between flux emergence and decay
JF  - Polymers
N2  - Context. The solar magnetic field is responsible for all aspects of solar activity. Thus, emergence of magnetic flux at the surface is the first manifestation of the ensuing solar activity. Aims. Combining high-resolution and synoptic observations aims to provide a comprehensive description of flux emergence at photospheric level and of the growth process that eventually leads to a mature active region. Methods. The small active region NOAA 12118 emerged on 2014 July 17 and was observed one day later with the 1.5-m GREGOR solar telescope on 2014 July 18. High-resolution time-series of blue continuum and G-band images acquired in the blue imaging channel (BIC) of the GREGOR Fabry-Perot Interferometer (GFPI) were complemented by synoptic line-of-sight magnetograms and continuum images obtained with the Helioseismic and Magnetic Imager (HMI) onboard the Solar Dynamics Observatory (SDO). Horizontal proper motions and horizontal plasma velocities were computed with local correlation tracking (LCT) and the differential affine velocity estimator (DAVE), respectively. Morphological image processing was employed to measure the photometric and magnetic area, magnetic flux, and the separation profile of the emerging flux region during its evolution. Results. The computed growth rates for photometric area, magnetic area, and magnetic flux are about twice as high as the respective decay rates. The space-time diagram using HMI magnetograms of five days provides a comprehensive view of growth and decay. It traces a leaf-like structure, which is determined by the initial separation of the two polarities, a rapid expansion phase, a time when the spread stalls, and a period when the region slowly shrinks again. The separation rate of 0.26 km s(-1) is highest in the initial stage, and it decreases when the separation comes to a halt. Horizontal plasma velocities computed at four evolutionary stages indicate a changing pattern of inflows. In LCT maps we find persistent flow patterns such as outward motions in the outer part of the two major pores, a diverging feature near the trailing pore marking the site of upwelling plasma and flux emergence, and low velocities in the interior of dark pores. We detected many elongated rapidly expanding granules between the two major polarities, with dimensions twice as large as the normal granules.
KW  - Sun: photosphere
KW  - Sun: magnetic fields
KW  - techniques: image processing
KW  - methods: data analysis
Y1  - 2016
U6  - https://doi.org/10.1051/0004-6361/201628380
SN  - 1432-0746
VL  - 596
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Balthasar, H.
A1  - Gömöry, P.
A1  - González Manrique, Sergio Javier
A1  - Kuckein, Christoph
A1  - Kavka, J.
A1  - Kucera, A.
A1  - Schwartz, P.
A1  - Vaskova, R.
A1  - Berkefeld, T.
A1  - Collados Vera, M.
A1  - Denker, Carsten
A1  - Feller, A.
A1  - Hofmann, A.
A1  - Lagg, A.
A1  - Nicklas, H.
A1  - Suarez, D.
A1  - Pastor Yabar, A.
A1  - Rezaei, R.
A1  - Schlichenmaier, R.
A1  - Schmidt, D.
A1  - Schmidt, W.
A1  - Sigwarth, M.
A1  - Sobotka, M.
A1  - Solanki, S. K.
A1  - Soltau, D.
A1  - Staude, J.
A1  - Strassmeier, Klaus G.
A1  - Volkmer, R.
A1  - von der Lühe, O.
A1  - Waldmann, T.
T1  - Spectropolarimetric observations of an arch filament system with the GREGOR solar telescope
JF  - Astronomische Nachrichten = Astronomical notes
N2  - Arch filament systems occur in active sunspot groups, where a fibril structure connects areas of opposite magnetic polarity, in contrast to active region filaments that follow the polarity inversion line. We used the GREGOR Infrared Spectrograph (GRIS) to obtain the full Stokes vector in the spectral lines SiI lambda 1082.7 nm, He I lambda 1083.0 nm, and Ca I lambda 1083.9 nm. We focus on the near-infrared calcium line to investigate the photospheric magnetic field and velocities, and use the line core intensities and velocities of the helium line to study the chromospheric plasma. The individual fibrils of the arch filament system connect the sunspot with patches of magnetic polarity opposite to that of the spot. These patches do not necessarily coincide with pores, where the magnetic field is strongest. Instead, areas are preferred not far from the polarity inversion line. These areas exhibit photospheric downflows of moderate velocity, but significantly higher downflows of up to 30 km s(-1) in the chromospheric helium line. Our findings can be explained with new emerging flux where the matter flows downward along the field lines of rising flux tubes, in agreement with earlier results. (C) 2016 WILEY-VCH Verlag GmbH& Co. KGaA, Weinheim
KW  - Sun: filaments
KW  - Sun: photosphere
KW  - techniques: polarimetric
KW  - techniques: spectroscopic
Y1  - 2016
U6  - https://doi.org/10.1002/asna.201612432
SN  - 0004-6337
SN  - 1521-3994
VL  - 337
SP  - 1050
EP  - 1056
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Gonzalez Manrique, Sergio Javier
A1  - Kuckein, Christoph
A1  - Pastor Yabar, A.
A1  - Collados Vera, M.
A1  - Denker, Carsten
A1  - Fischer, C. E.
A1  - Gömöry, P.
A1  - Diercke, Andrea
A1  - Gonzalez, N. Bello
A1  - Schlichenmaier, R.
A1  - Balthasar, H.
A1  - Berkefeld, T.
A1  - Feller, A.
A1  - Hoch, S.
A1  - Hofmann, A.
A1  - Kneer, F.
A1  - Lagg, A.
A1  - Nicklas, H.
A1  - Orozco Suarez, D.
A1  - Schmidt, D.
A1  - Schmidt, W.
A1  - Sigwarth, M.
A1  - Sobotka, M.
A1  - Solanki, S. K.
A1  - Soltau, D.
A1  - Staude, J.
A1  - Strassmeier, Klaus G.
A1  - Verma, Meetu
A1  - Volkmer, R.
A1  - von der Lühe, O.
A1  - Waldmann, T.
T1  - Fitting peculiar spectral profiles in He I 10830 angstrom absorption features
JF  - Astronomische Nachrichten = Astronomical notes
N2  - The new generation of solar instruments provides better spectral, spatial, and temporal resolution for a better understanding of the physical processes that take place on the Sun. Multiple-component profiles are more commonly observed with these instruments. Particularly, the He i 10830 triplet presents such peculiar spectral profiles, which give information on the velocity and magnetic fine structure of the upper chromosphere. The purpose of this investigation is to describe a technique to efficiently fit the two blended components of the He i 10830 triplet, which are commonly observed when two atmospheric components are located within the same resolution element. The observations used in this study were taken on 2015 April 17 with the very fast spectroscopic mode of the GREGOR Infrared Spectrograph (GRIS) attached to the 1.5-m GREGOR solar telescope, located at the Observatorio del Teide, Tenerife, Spain. We apply a double-Lorentzian fitting technique using Levenberg-Marquardt least-squares minimization. This technique is very simple and much faster than inversion codes. Line-of-sight Doppler velocities can be inferred for a whole map of pixels within just a few minutes. Our results show sub-and supersonic downflow velocities of up to 32 km s(-1) for the fast component in the vicinity of footpoints of filamentary structures. The slow component presents velocities close to rest. (C) 2016 WILEY-VCH Verlag GmbH& Co. KGaA, Weinheim
KW  - Sun: chromosphere
KW  - methods: data analysis
KW  - techniques: spectroscopic
KW  - line: profiles
Y1  - 2016
U6  - https://doi.org/10.1002/asna.201512433
SN  - 0004-6337
SN  - 1521-3994
VL  - 337
SP  - 1057
EP  - 1063
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Verma, Meetu
A1  - Denker, Carsten
A1  - Böhm, F.
A1  - Balthasar, H.
A1  - Fischer, C. E.
A1  - Kuckein, Christoph
A1  - Gonzalez, N. Bello
A1  - Berkefeld, T.
A1  - Collados Vera, M.
A1  - Diercke, Andrea
A1  - Feller, A.
A1  - Gonzalez Manrique, Sergio Javier
A1  - Hofmann, A.
A1  - Lagg, A.
A1  - Nicklas, H.
A1  - Orozco Suarez, D.
A1  - Pator Yabar, A.
A1  - Rezaei, R.
A1  - Schlichenmaier, R.
A1  - Schmidt, D.
A1  - Schmidt, W.
A1  - Sigwarth, M.
A1  - Sobotka, M.
A1  - Solanki, S. K.
A1  - Soltau, D.
A1  - Staude, J.
A1  - Strassmeier, Klaus G.
A1  - Volkmer, R.
A1  - von der Lühe, O.
A1  - Waldmann, T.
T1  - Flow and magnetic field properties in the trailing sunspots of active region NOAA 12396
JF  - Astronomische Nachrichten = Astronomical notes
N2  - Improved measurements of the photospheric and chromospheric three-dimensional magnetic and flow fields are crucial for a precise determination of the origin and evolution of active regions. We present an illustrative sample of multi-instrument data acquired during a two-week coordinated observing campaign in August 2015 involving, among others, the GREGOR solar telescope (imaging and near-infrared spectroscopy) and the space missions Solar Dynamics Observatory (SDO) and Interface Region Imaging Spectrograph (IRIS). The observations focused on the trailing part of active region NOAA 12396 with complex polarity inversion lines and strong intrusions of opposite polarity flux. The GREGOR Infrared Spectrograph (GRIS) provided Stokes IQUV spectral profiles in the photospheric Si i.1082.7 nm line, the chromospheric He I lambda 1083.0 nm triplet, and the photospheric Ca I lambda 1083.9 nm line. Carefully calibrated GRIS scans of the active region provided maps of Doppler velocity and magnetic field at different atmospheric heights. We compare quick-look maps with those obtained with the " Stokes Inversions based on Response functions" (SIR) code, which furnishes deeper insight into the magnetic properties of the region. We find supporting evidence that newly emerging flux and intruding opposite polarity flux are hampering the formation of penumbrae, i.e., a penumbra fully surrounding a sunspot is only expected after cessation of flux emergence in proximity to the sunspots. (C) 2016 WILEY-VCH Verlag GmbH& Co.KGaA, Weinheim
KW  - Sun: magnetic fields
KW  - sunspots
KW  - methods: data analysis
KW  - techniques: polarimetric
KW  - techniques: spectroscopic
Y1  - 2016
U6  - https://doi.org/10.1002/asna.201612447
SN  - 0004-6337
SN  - 1521-3994
VL  - 337
SP  - 1090
EP  - 1098
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - GEN
A1  - Gorski, Mathias
A1  - Jung, Bettina
A1  - Li, Yong
A1  - Matias-Garcia, Pamela R.
A1  - Wuttke, Matthias
A1  - Coassin, Stefan
A1  - Thio, Chris H. L.
A1  - Kleber, Marcus E.
A1  - Winkler, Thomas W.
A1  - Wanner, Veronika
A1  - Chai, Jin-Fang
A1  - Chu, Audrey Y.
A1  - Cocca, Massimiliano
A1  - Feitosa, Mary F.
A1  - Ghasemi, Sahar
A1  - Hoppmann, Anselm
A1  - Horn, Katrin
A1  - Li, Man
A1  - Nutile, Teresa
A1  - Scholz, Markus
A1  - Sieber, Karsten B.
A1  - Teumer, Alexander
A1  - Tin, Adrienne
A1  - Wang, Judy
A1  - Tayo, Bamidele O.
A1  - Ahluwalia, Tarunveer S.
A1  - Almgren, Peter
A1  - Bakker, Stephan J. L.
A1  - Banas, Bernhard
A1  - Bansal, Nisha
A1  - Biggs, Mary L.
A1  - Boerwinkle, Eric
A1  - Böttinger, Erwin
A1  - Brenner, Hermann
A1  - Carroll, Robert J.
A1  - Chalmers, John
A1  - Chee, Miao-Li
A1  - Chee, Miao-Ling
A1  - Cheng, Ching-Yu
A1  - Coresh, Josef
A1  - de Borst, Martin H.
A1  - Degenhardt, Frauke
A1  - Eckardt, Kai-Uwe
A1  - Endlich, Karlhans
A1  - Franke, Andre
A1  - Freitag-Wolf, Sandra
A1  - Gampawar, Piyush
A1  - Gansevoort, Ron T.
A1  - Ghanbari, Mohsen
A1  - Gieger, Christian
A1  - Hamet, Pavel
A1  - Ho, Kevin
A1  - Hofer, Edith
A1  - Holleczek, Bernd
A1  - Foo, Valencia Hui Xian
A1  - Hutri-Kahonen, Nina
A1  - Hwang, Shih-Jen
A1  - Ikram, M. Arfan
A1  - Josyula, Navya Shilpa
A1  - Kahonen, Mika
A1  - Khor, Chiea-Chuen
A1  - Koenig, Wolfgang
A1  - Kramer, Holly
A1  - Kraemer, Bernhard K.
A1  - Kuehnel, Brigitte
A1  - Lange, Leslie A.
A1  - Lehtimaki, Terho
A1  - Lieb, Wolfgang
A1  - Loos, Ruth J. F.
A1  - Lukas, Mary Ann
A1  - Lyytikainen, Leo-Pekka
A1  - Meisinger, Christa
A1  - Meitinger, Thomas
A1  - Melander, Olle
A1  - Milaneschi, Yuri
A1  - Mishra, Pashupati P.
A1  - Mononen, Nina
A1  - Mychaleckyj, Josyf C.
A1  - Nadkarni, Girish N.
A1  - Nauck, Matthias
A1  - Nikus, Kjell
A1  - Ning, Boting
A1  - Nolte, Ilja M.
A1  - O'Donoghue, Michelle L.
A1  - Orho-Melander, Marju
A1  - Pendergrass, Sarah A.
A1  - Penninx, Brenda W. J. H.
A1  - Preuss, Michael H.
A1  - Psaty, Bruce M.
A1  - Raffield, Laura M.
A1  - Raitakari, Olli T.
A1  - Rettig, Rainer
A1  - Rheinberger, Myriam
A1  - Rice, Kenneth M.
A1  - Rosenkranz, Alexander R.
A1  - Rossing, Peter
A1  - Rotter, Jerome
A1  - Sabanayagam, Charumathi
A1  - Schmidt, Helena
A1  - Schmidt, Reinhold
A1  - Schoettker, Ben
A1  - Schulz, Christina-Alexandra
A1  - Sedaghat, Sanaz
A1  - Shaffer, Christian M.
A1  - Strauch, Konstantin
A1  - Szymczak, Silke
A1  - Taylor, Kent D.
A1  - Tremblay, Johanne
A1  - Chaker, Layal
A1  - van der Harst, Pim
A1  - van der Most, Peter J.
A1  - Verweij, Niek
A1  - Voelker, Uwe
A1  - Waldenberger, Melanie
A1  - Wallentin, Lars
A1  - Waterworth, Dawn M.
A1  - White, Harvey D.
A1  - Wilson, James G.
A1  - Wong, Tien-Yin
A1  - Woodward, Mark
A1  - Yang, Qiong
A1  - Yasuda, Masayuki
A1  - Yerges-Armstrong, Laura M.
A1  - Zhang, Yan
A1  - Snieder, Harold
A1  - Wanner, Christoph
A1  - Boger, Carsten A.
A1  - Kottgen, Anna
A1  - Kronenberg, Florian
A1  - Pattaro, Cristian
A1  - Heid, Iris M.
T1  - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline
T2  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät
N2  - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.
T3  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät - 19 
KW  - acute kidney injury
KW  - end-stage kidney disease
KW  - genome-wide association
KW  - study
KW  - rapid eGFRcrea decline
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-565379
IS  - 19
ER  - 
TY  - JOUR
A1  - Gorski, Mathias
A1  - Jung, Bettina
A1  - Li, Yong
A1  - Matias-Garcia, Pamela R.
A1  - Wuttke, Matthias
A1  - Coassin, Stefan
A1  - Thio, Chris H. L.
A1  - Kleber, Marcus E.
A1  - Winkler, Thomas W.
A1  - Wanner, Veronika
A1  - Chai, Jin-Fang
A1  - Chu, Audrey Y.
A1  - Cocca, Massimiliano
A1  - Feitosa, Mary F.
A1  - Ghasemi, Sahar
A1  - Hoppmann, Anselm
A1  - Horn, Katrin
A1  - Li, Man
A1  - Nutile, Teresa
A1  - Scholz, Markus
A1  - Sieber, Karsten B.
A1  - Teumer, Alexander
A1  - Tin, Adrienne
A1  - Wang, Judy
A1  - Tayo, Bamidele O.
A1  - Ahluwalia, Tarunveer S.
A1  - Almgren, Peter
A1  - Bakker, Stephan J. L.
A1  - Banas, Bernhard
A1  - Bansal, Nisha
A1  - Biggs, Mary L.
A1  - Boerwinkle, Eric
A1  - Böttinger, Erwin
A1  - Brenner, Hermann
A1  - Carroll, Robert J.
A1  - Chalmers, John
A1  - Chee, Miao-Li
A1  - Chee, Miao-Ling
A1  - Cheng, Ching-Yu
A1  - Coresh, Josef
A1  - de Borst, Martin H.
A1  - Degenhardt, Frauke
A1  - Eckardt, Kai-Uwe
A1  - Endlich, Karlhans
A1  - Franke, Andre
A1  - Freitag-Wolf, Sandra
A1  - Gampawar, Piyush
A1  - Gansevoort, Ron T.
A1  - Ghanbari, Mohsen
A1  - Gieger, Christian
A1  - Hamet, Pavel
A1  - Ho, Kevin
A1  - Hofer, Edith
A1  - Holleczek, Bernd
A1  - Foo, Valencia Hui Xian
A1  - Hutri-Kahonen, Nina
A1  - Hwang, Shih-Jen
A1  - Ikram, M. Arfan
A1  - Josyula, Navya Shilpa
A1  - Kahonen, Mika
A1  - Khor, Chiea-Chuen
A1  - Koenig, Wolfgang
A1  - Kramer, Holly
A1  - Kraemer, Bernhard K.
A1  - Kuehnel, Brigitte
A1  - Lange, Leslie A.
A1  - Lehtimaki, Terho
A1  - Lieb, Wolfgang
A1  - Loos, Ruth J. F.
A1  - Lukas, Mary Ann
A1  - Lyytikainen, Leo-Pekka
A1  - Meisinger, Christa
A1  - Meitinger, Thomas
A1  - Melander, Olle
A1  - Milaneschi, Yuri
A1  - Mishra, Pashupati P.
A1  - Mononen, Nina
A1  - Mychaleckyj, Josyf C.
A1  - Nadkarni, Girish N.
A1  - Nauck, Matthias
A1  - Nikus, Kjell
A1  - Ning, Boting
A1  - Nolte, Ilja M.
A1  - O'Donoghue, Michelle L.
A1  - Orho-Melander, Marju
A1  - Pendergrass, Sarah A.
A1  - Penninx, Brenda W. J. H.
A1  - Preuss, Michael H.
A1  - Psaty, Bruce M.
A1  - Raffield, Laura M.
A1  - Raitakari, Olli T.
A1  - Rettig, Rainer
A1  - Rheinberger, Myriam
A1  - Rice, Kenneth M.
A1  - Rosenkranz, Alexander R.
A1  - Rossing, Peter
A1  - Rotter, Jerome
A1  - Sabanayagam, Charumathi
A1  - Schmidt, Helena
A1  - Schmidt, Reinhold
A1  - Schoettker, Ben
A1  - Schulz, Christina-Alexandra
A1  - Sedaghat, Sanaz
A1  - Shaffer, Christian M.
A1  - Strauch, Konstantin
A1  - Szymczak, Silke
A1  - Taylor, Kent D.
A1  - Tremblay, Johanne
A1  - Chaker, Layal
A1  - van der Harst, Pim
A1  - van der Most, Peter J.
A1  - Verweij, Niek
A1  - Voelker, Uwe
A1  - Waldenberger, Melanie
A1  - Wallentin, Lars
A1  - Waterworth, Dawn M.
A1  - White, Harvey D.
A1  - Wilson, James G.
A1  - Wong, Tien-Yin
A1  - Woodward, Mark
A1  - Yang, Qiong
A1  - Yasuda, Masayuki
A1  - Yerges-Armstrong, Laura M.
A1  - Zhang, Yan
A1  - Snieder, Harold
A1  - Wanner, Christoph
A1  - Boger, Carsten A.
A1  - Kottgen, Anna
A1  - Kronenberg, Florian
A1  - Pattaro, Cristian
A1  - Heid, Iris M.
T1  - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline
JF  - Kidney international : official journal of the International Society of Nephrology
N2  - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.
KW  - acute kidney injury
KW  - end-stage kidney disease
KW  - genome-wide association
KW  - study
KW  - rapid eGFRcrea decline
Y1  - 2020
U6  - https://doi.org/10.1016/j.kint.2020.09.030
SN  - 0085-2538
SN  - 1523-1755
VL  - 99
IS  - 4
SP  - 926
EP  - 939
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Aldoretta, E. J.
A1  - St-Louis, N.
A1  - Richardson, N. D.
A1  - Moffat, Anthony F. J.
A1  - Eversberg, T.
A1  - Hill, G. M.
A1  - Shenar, Tomer
A1  - Artigau, E.
A1  - Gauza, B.
A1  - Knapen, J. H.
A1  - Kubat, Jiří
A1  - Kubatova, Brankica
A1  - Maltais-Tariant, R.
A1  - Munoz, M.
A1  - Pablo, H.
A1  - Ramiaramanantsoa, T.
A1  - Richard-Laferriere, A.
A1  - Sablowski, D. P.
A1  - Simon-Diaz, S.
A1  - St-Jean, L.
A1  - Bolduan, F.
A1  - Dias, F. M.
A1  - Dubreuil, P.
A1  - Fuchs, D.
A1  - Garrel, T.
A1  - Grutzeck, G.
A1  - Hunger, T.
A1  - Kuesters, D.
A1  - Langenbrink, M.
A1  - Leadbeater, R.
A1  - Li, D.
A1  - Lopez, A.
A1  - Mauclaire, B.
A1  - Moldenhawer, T.
A1  - Potter, M.
A1  - dos Santos, E. M.
A1  - Schanne, L.
A1  - Schmidt, J.
A1  - Sieske, H.
A1  - Strachan, J.
A1  - Stinner, E.
A1  - Stinner, P.
A1  - Stober, B.
A1  - Strandbaek, K.
A1  - Syder, T.
A1  - Verilhac, D.
A1  - Waldschlaeger, U.
A1  - Weiss, D.
A1  - Wendt, A.
T1  - An extensive spectroscopic time series of three Wolf-Rayet stars - I. The lifetime of large-scale structures in the wind of WR 134
JF  - Monthly notices of the Royal Astronomical Society
N2  - During the summer of 2013, a 4-month spectroscopic campaign took place to observe the variabilities in three Wolf-Rayet stars. The spectroscopic data have been analysed for WR 134 (WN6b), to better understand its behaviour and long-term periodicity, which we interpret as arising from corotating interaction regions (CIRs) in the wind. By analysing the variability of the He ii lambda 5411 emission line, the previously identified period was refined to P = 2.255 +/- 0.008 (s.d.) d. The coherency time of the variability, which we associate with the lifetime of the CIRs in the wind, was deduced to be 40 +/- 6 d, or similar to 18 cycles, by cross-correlating the variability patterns as a function of time. When comparing the phased observational grey-scale difference images with theoretical grey-scales previously calculated from models including CIRs in an optically thin stellar wind, we find that two CIRs were likely present. A separation in longitude of Delta I center dot a parts per thousand integral 90A degrees was determined between the two CIRs and we suggest that the different maximum velocities that they reach indicate that they emerge from different latitudes. We have also been able to detect observational signatures of the CIRs in other spectral lines (C iv lambda lambda 5802,5812 and He i lambda 5876). Furthermore, a DAC was found to be present simultaneously with the CIR signatures detected in the He i lambda 5876 emission line which is consistent with the proposed geometry of the large-scale structures in the wind. Small-scale structures also show a presence in the wind, simultaneously with the larger scale structures, showing that they do in fact co-exist.
KW  - instabilities
KW  - methods: data analysis
KW  - techniques: spectroscopic
KW  - stars: individual: WR 134
KW  - stars: massive
KW  - stars: Wolf-Rayet
Y1  - 2016
U6  - https://doi.org/10.1093/mnras/stw1188
SN  - 0035-8711
SN  - 1365-2966
VL  - 460
SP  - 3407
EP  - 3417
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Srama, Ralf
A1  - Krueger, H.
A1  - Yamaguchi, T.
A1  - Stephan, T.
A1  - Burchell, M.
A1  - Kearsley, A. T.
A1  - Sterken, V.
A1  - Postberg, F.
A1  - Kempf, S.
A1  - Grün, Eberhard
A1  - Altobelli, Nicolas
A1  - Ehrenfreund, P.
A1  - Dikarev, V.
A1  - Horanyi, M.
A1  - Sternovsky, Zoltan
A1  - Carpenter, J. D.
A1  - Westphal, A.
A1  - Gainsforth, Z.
A1  - Krabbe, A.
A1  - Agarwal, Jessica
A1  - Yano, H.
A1  - Blum, J.
A1  - Henkel, H.
A1  - Hillier, J.
A1  - Hoppe, P.
A1  - Trieloff, M.
A1  - Hsu, S.
A1  - Mocker, A.
A1  - Fiege, K.
A1  - Green, S. F.
A1  - Bischoff, A.
A1  - Esposito, F.
A1  - Laufer, R.
A1  - Hyde, T. W.
A1  - Herdrich, G.
A1  - Fasoulas, S.
A1  - Jaeckel, A.
A1  - Jones, G.
A1  - Jenniskens, P.
A1  - Khalisi, E.
A1  - Moragas-Klostermeyer, Georg
A1  - Spahn, Frank
A1  - Keller, H. U.
A1  - Frisch, P.
A1  - Levasseur-Regourd, A. C.
A1  - Pailer, N.
A1  - Altwegg, K.
A1  - Engrand, C.
A1  - Auer, S.
A1  - Silen, J.
A1  - Sasaki, S.
A1  - Kobayashi, M.
A1  - Schmidt, J.
A1  - Kissel, J.
A1  - Marty, B.
A1  - Michel, P.
A1  - Palumbo, P.
A1  - Vaisberg, O.
A1  - Baggaley, J.
A1  - Rotundi, A.
A1  - Roeser, H. P.
T1  - SARIM PLUS-sample return of comet 67P/CG and of interstellar matter
JF  - EXPERIMENTAL ASTRONOMY
N2  - The Stardust mission returned cometary, interplanetary and (probably) interstellar dust in 2006 to Earth that have been analysed in Earth laboratories worldwide. Results of this mission have changed our view and knowledge on the early solar nebula. The Rosetta mission is on its way to land on comet 67P/Churyumov-Gerasimenko and will investigate for the first time in great detail the comet nucleus and its environment starting in 2014. Additional astronomy and planetary space missions will further contribute to our understanding of dust generation, evolution and destruction in interstellar and interplanetary space and provide constraints on solar system formation and processes that led to the origin of life on Earth. One of these missions, SARIM-PLUS, will provide a unique perspective by measuring interplanetary and interstellar dust with high accuracy and sensitivity in our inner solar system between 1 and 2 AU. SARIM-PLUS employs latest in-situ techniques for a full characterisation of individual micrometeoroids (flux, mass, charge, trajectory, composition()) and collects and returns these samples to Earth for a detailed analysis. The opportunity to visit again the target comet of the Rosetta mission 67P/Churyumov-Gerasimeenternko, and to investigate its dusty environment six years after Rosetta with complementary methods is unique and strongly enhances and supports the scientific exploration of this target and the entire Rosetta mission. Launch opportunities are in 2020 with a backup window starting early 2026. The comet encounter occurs in September 2021 and the reentry takes place in early 2024. An encounter speed of 6 km/s ensures comparable results to the Stardust mission.
KW  - Interstellar dust
KW  - Cometary dust
KW  - Churyumov Gerasimenko
KW  - Interplanetary dust
KW  - IMF
KW  - Cosmic vision
KW  - Sample return
KW  - Dust collector
KW  - Mass spectrometry
Y1  - 2012
U6  - https://doi.org/10.1007/s10686-011-9285-7
SN  - 0922-6435
SN  - 1572-9508
VL  - 33
IS  - 2-3
SP  - 723
EP  - 751
PB  - SPRINGER
CY  - DORDRECHT
ER  - 
TY  - JOUR
A1  - Aarts, Alexander A.
A1  - Anderson, Joanna E.
A1  - Anderson, Christopher J.
A1  - Attridge, Peter R.
A1  - Attwood, Angela
A1  - Axt, Jordan
A1  - Babel, Molly
A1  - Bahnik, Stepan
A1  - Baranski, Erica
A1  - Barnett-Cowan, Michael
A1  - Bartmess, Elizabeth
A1  - Beer, Jennifer
A1  - Bell, Raoul
A1  - Bentley, Heather
A1  - Beyan, Leah
A1  - Binion, Grace
A1  - Borsboom, Denny
A1  - Bosch, Annick
A1  - Bosco, Frank A.
A1  - Bowman, Sara D.
A1  - Brandt, Mark J.
A1  - Braswell, Erin
A1  - Brohmer, Hilmar
A1  - Brown, Benjamin T.
A1  - Brown, Kristina
A1  - Bruening, Jovita
A1  - Calhoun-Sauls, Ann
A1  - Callahan, Shannon P.
A1  - Chagnon, Elizabeth
A1  - Chandler, Jesse
A1  - Chartier, Christopher R.
A1  - Cheung, Felix
A1  - Christopherson, Cody D.
A1  - Cillessen, Linda
A1  - Clay, Russ
A1  - Cleary, Hayley
A1  - Cloud, Mark D.
A1  - Cohn, Michael
A1  - Cohoon, Johanna
A1  - Columbus, Simon
A1  - Cordes, Andreas
A1  - Costantini, Giulio
A1  - Alvarez, Leslie D. Cramblet
A1  - Cremata, Ed
A1  - Crusius, Jan
A1  - DeCoster, Jamie
A1  - DeGaetano, Michelle A.
A1  - Della Penna, Nicolas
A1  - den Bezemer, Bobby
A1  - Deserno, Marie K.
A1  - Devitt, Olivia
A1  - Dewitte, Laura
A1  - Dobolyi, David G.
A1  - Dodson, Geneva T.
A1  - Donnellan, M. Brent
A1  - Donohue, Ryan
A1  - Dore, Rebecca A.
A1  - Dorrough, Angela
A1  - Dreber, Anna
A1  - Dugas, Michelle
A1  - Dunn, Elizabeth W.
A1  - Easey, Kayleigh
A1  - Eboigbe, Sylvia
A1  - Eggleston, Casey
A1  - Embley, Jo
A1  - Epskamp, Sacha
A1  - Errington, Timothy M.
A1  - Estel, Vivien
A1  - Farach, Frank J.
A1  - Feather, Jenelle
A1  - Fedor, Anna
A1  - Fernandez-Castilla, Belen
A1  - Fiedler, Susann
A1  - Field, James G.
A1  - Fitneva, Stanka A.
A1  - Flagan, Taru
A1  - Forest, Amanda L.
A1  - Forsell, Eskil
A1  - Foster, Joshua D.
A1  - Frank, Michael C.
A1  - Frazier, Rebecca S.
A1  - Fuchs, Heather
A1  - Gable, Philip
A1  - Galak, Jeff
A1  - Galliani, Elisa Maria
A1  - Gampa, Anup
A1  - Garcia, Sara
A1  - Gazarian, Douglas
A1  - Gilbert, Elizabeth
A1  - Giner-Sorolla, Roger
A1  - Glöckner, Andreas
A1  - Göllner, Lars
A1  - Goh, Jin X.
A1  - Goldberg, Rebecca
A1  - Goodbourn, Patrick T.
A1  - Gordon-McKeon, Shauna
A1  - Gorges, Bryan
A1  - Gorges, Jessie
A1  - Goss, Justin
A1  - Graham, Jesse
A1  - Grange, James A.
A1  - Gray, Jeremy
A1  - Hartgerink, Chris
A1  - Hartshorne, Joshua
A1  - Hasselman, Fred
A1  - Hayes, Timothy
A1  - Heikensten, Emma
A1  - Henninger, Felix
A1  - Hodsoll, John
A1  - Holubar, Taylor
A1  - Hoogendoorn, Gea
A1  - Humphries, Denise J.
A1  - Hung, Cathy O. -Y.
A1  - Immelman, Nathali
A1  - Irsik, Vanessa C.
A1  - Jahn, Georg
A1  - Jaekel, Frank
A1  - Jekel, Marc
A1  - Johannesson, Magnus
A1  - Johnson, Larissa G.
A1  - Johnson, David J.
A1  - Johnson, Kate M.
A1  - Johnston, William J.
A1  - Jonas, Kai
A1  - Joy-Gaba, Jennifer A.
A1  - Kappes, Heather Barry
A1  - Kelso, Kim
A1  - Kidwell, Mallory C.
A1  - Kim, Seung Kyung
A1  - Kirkhart, Matthew
A1  - Kleinberg, Bennett
A1  - Knezevic, Goran
A1  - Kolorz, Franziska Maria
A1  - Kossakowski, Jolanda J.
A1  - Krause, Robert Wilhelm
A1  - Krijnen, Job
A1  - Kuhlmann, Tim
A1  - Kunkels, Yoram K.
A1  - Kyc, Megan M.
A1  - Lai, Calvin K.
A1  - Laique, Aamir
A1  - Lakens, Daniel
A1  - Lane, Kristin A.
A1  - Lassetter, Bethany
A1  - Lazarevic, Ljiljana B.
A1  - LeBel, Etienne P.
A1  - Lee, Key Jung
A1  - Lee, Minha
A1  - Lemm, Kristi
A1  - Levitan, Carmel A.
A1  - Lewis, Melissa
A1  - Lin, Lin
A1  - Lin, Stephanie
A1  - Lippold, Matthias
A1  - Loureiro, Darren
A1  - Luteijn, Ilse
A1  - Mackinnon, Sean
A1  - Mainard, Heather N.
A1  - Marigold, Denise C.
A1  - Martin, Daniel P.
A1  - Martinez, Tylar
A1  - Masicampo, E. J.
A1  - Matacotta, Josh
A1  - Mathur, Maya
A1  - May, Michael
A1  - Mechin, Nicole
A1  - Mehta, Pranjal
A1  - Meixner, Johannes
A1  - Melinger, Alissa
A1  - Miller, Jeremy K.
A1  - Miller, Mallorie
A1  - Moore, Katherine
A1  - Möschl, Marcus
A1  - Motyl, Matt
A1  - Müller, Stephanie M.
A1  - Munafo, Marcus
A1  - Neijenhuijs, Koen I.
A1  - Nervi, Taylor
A1  - Nicolas, Gandalf
A1  - Nilsonne, Gustav
A1  - Nosek, Brian A.
A1  - Nuijten, Michele B.
A1  - Olsson, Catherine
A1  - Osborne, Colleen
A1  - Ostkamp, Lutz
A1  - Pavel, Misha
A1  - Penton-Voak, Ian S.
A1  - Perna, Olivia
A1  - Pernet, Cyril
A1  - Perugini, Marco
A1  - Pipitone, R. Nathan
A1  - Pitts, Michael
A1  - Plessow, Franziska
A1  - Prenoveau, Jason M.
A1  - Rahal, Rima-Maria
A1  - Ratliff, Kate A.
A1  - Reinhard, David
A1  - Renkewitz, Frank
A1  - Ricker, Ashley A.
A1  - Rigney, Anastasia
A1  - Rivers, Andrew M.
A1  - Roebke, Mark
A1  - Rutchick, Abraham M.
A1  - Ryan, Robert S.
A1  - Sahin, Onur
A1  - Saide, Anondah
A1  - Sandstrom, Gillian M.
A1  - Santos, David
A1  - Saxe, Rebecca
A1  - Schlegelmilch, Rene
A1  - Schmidt, Kathleen
A1  - Scholz, Sabine
A1  - Seibel, Larissa
A1  - Selterman, Dylan Faulkner
A1  - Shaki, Samuel
A1  - Simpson, William B.
A1  - Sinclair, H. Colleen
A1  - Skorinko, Jeanine L. M.
A1  - Slowik, Agnieszka
A1  - Snyder, Joel S.
A1  - Soderberg, Courtney
A1  - Sonnleitner, Carina
A1  - Spencer, Nick
A1  - Spies, Jeffrey R.
A1  - Steegen, Sara
A1  - Stieger, Stefan
A1  - Strohminger, Nina
A1  - Sullivan, Gavin B.
A1  - Talhelm, Thomas
A1  - Tapia, Megan
A1  - te Dorsthorst, Anniek
A1  - Thomae, Manuela
A1  - Thomas, Sarah L.
A1  - Tio, Pia
A1  - Traets, Frits
A1  - Tsang, Steve
A1  - Tuerlinckx, Francis
A1  - Turchan, Paul
A1  - Valasek, Milan
A1  - Van Aert, Robbie
A1  - van Assen, Marcel
A1  - van Bork, Riet
A1  - van de Ven, Mathijs
A1  - van den Bergh, Don
A1  - van der Hulst, Marije
A1  - van Dooren, Roel
A1  - van Doorn, Johnny
A1  - van Renswoude, Daan R.
A1  - van Rijn, Hedderik
A1  - Vanpaemel, Wolf
A1  - Echeverria, Alejandro Vasquez
A1  - Vazquez, Melissa
A1  - Velez, Natalia
A1  - Vermue, Marieke
A1  - Verschoor, Mark
A1  - Vianello, Michelangelo
A1  - Voracek, Martin
A1  - Vuu, Gina
A1  - Wagenmakers, Eric-Jan
A1  - Weerdmeester, Joanneke
A1  - Welsh, Ashlee
A1  - Westgate, Erin C.
A1  - Wissink, Joeri
A1  - Wood, Michael
A1  - Woods, Andy
A1  - Wright, Emily
A1  - Wu, Sining
A1  - Zeelenberg, Marcel
A1  - Zuni, Kellylynn
T1  - Estimating the reproducibility of psychological science
JF  - Science
N2  - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.
Y1  - 2015
U6  - https://doi.org/10.1126/science.aac4716
SN  - 1095-9203
SN  - 0036-8075
VL  - 349
IS  - 6251
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - JOUR
A1  - Altmann, Thomas
A1  - Törjek, Otto
A1  - Berger, Dieter
A1  - Meyer, Rhonda C.
A1  - Müssig, Carsten
A1  - Schmidt, K. J.
A1  - Sorensen, T. R.
A1  - Weisshaar, Bernd
A1  - Olds-Mitchell, T.
T1  - Establishment of a high-efficiency SNP-based framework marker set for Arabidopsis
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Ijiri, Akira
A1  - Inagaki, Fumio
A1  - Kubo, Yusuke
A1  - Adhikari, Rishi Ram
A1  - Hattori, Shohei
A1  - Hoshino, Tatsuhiko
A1  - Imachi, Hiroyuki
A1  - Kawagucci, Shinsuke
A1  - Morono, Yuki
A1  - Ohtomo, Yoko
A1  - Ono, Shuhei
A1  - Sakai, Sanae
A1  - Takai, Ken
A1  - Toki, Tomohiro
A1  - Wang, David T.
A1  - Yoshinaga, Marcos Y.
A1  - Arnold, Gail L.
A1  - Ashi, Juichiro
A1  - Case, David H.
A1  - Feseker, Tomas
A1  - Hinrichs, Kai-Uwe
A1  - Ikegawa, Yojiro
A1  - Ikehara, Minoru
A1  - Kallmeyer, Jens
A1  - Kumagai, Hidenori
A1  - Lever, Mark Alexander
A1  - Morita, Sumito
A1  - Nakamura, Ko-ichi
A1  - Nakamura, Yuki
A1  - Nishizawa, Manabu
A1  - Orphan, Victoria J.
A1  - Roy, Hans
A1  - Schmidt, Frauke
A1  - Tani, Atsushi
A1  - Tanikawa, Wataru
A1  - Terada, Takeshi
A1  - Tomaru, Hitoshi
A1  - Tsuji, Takeshi
A1  - Tsunogai, Urumu
A1  - Yamaguchi, Yasuhiko T.
A1  - Yoshida, Naohiro
T1  - Deep-biosphere methane production stimulated by geofluids in the Nankai accretionary complex
JF  - Science Advances
Y1  - 2018
U6  - https://doi.org/10.1126/sciadv.aao4631
SN  - 2375-2548
VL  - 4
IS  - 6
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - GEN
A1  - Ijiri, Akira
A1  - Inagaki, Fumio
A1  - Kubo, Yusuke
A1  - Adhikari, Rishi Ram
A1  - Hattori, Shohei
A1  - Hoshino, Tatsuhiko
A1  - Imachi, Hiroyuki
A1  - Kawagucci, Shinsuke
A1  - Morono, Yuki
A1  - Ohtomo, Yoko
A1  - Ono, Shuhei
A1  - Sakai, Sanae
A1  - Takai, Ken
A1  - Toki, Tomohiro
A1  - Wang, David T.
A1  - Yoshinaga, Marcos Y.
A1  - Arnold, Gail L.
A1  - Ashi, Juichiro
A1  - Case, David H.
A1  - Feseker, Tomas
A1  - Hinrichs, Kai-Uwe
A1  - Ikegawa, Yojiro
A1  - Ikehara, Minoru
A1  - Kallmeyer, Jens
A1  - Kumagai, Hidenori
A1  - Lever, Mark Alexander
A1  - Morita, Sumito
A1  - Nakamura, Ko-ichi
A1  - Nakamura, Yuki
A1  - Nishizawa, Manabu
A1  - Orphan, Victoria J.
A1  - Røy, Hans
A1  - Schmidt, Frauke
A1  - Tani, Atsushi
A1  - Tanikawa, Wataru
A1  - Terada, Takeshi
A1  - Tomaru, Hitoshi
A1  - Tsuji, Takeshi
A1  - Tsunogai, Urumu
A1  - Yamaguchi, Yasuhiko T.
A1  - Yoshida, Naohiro
T1  - Deep-biosphere methane production stimulated by geofluids in the Nankai accretionary complex
T2  - Postprints der Universität Potsdam Mathematisch-Naturwissenschaftliche Reihe
N2  - Microbial life inhabiting subseafloor sediments plays an important role in Earth’s carbon cycle. However, the impact of geodynamic processes on the distributions and carbon-cycling activities of subseafloor life remains poorly constrained. We explore a submarine mud volcano of the Nankai accretionary complex by drilling down to 200 m below the summit. Stable isotopic compositions of water and carbon compounds, including clumped methane isotopologues, suggest that ~90% of methane is microbially produced at 16° to 30°C and 300 to 900 m below seafloor, corresponding to the basin bottom, where fluids in the accretionary prism are supplied via megasplay faults. Radiotracer experiments showed that relatively small microbial populations in deep mud volcano sediments (10 2 to 10 3 cells cm −3 ) include highly active hydrogenotrophic methanogens and acetogens. Our findings indicate that subduction-associated fluid migration has stimulated microbial activity in the mud reservoir and that mud volcanoes may contribute more substantially to the methane budget than previously estimated.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 802 
KW  - multiply-substituted isotopologues
KW  - marine subsurface sediments
KW  - carbon isotopic composition
KW  - submarine mud volcano
KW  - intact polar lipids
KW  - fore-arc basin
KW  - subseafloor sediments
KW  - microbial lipids
KW  - Cascadia margin
KW  - organic-acids
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-427002
SN  - 1866-8372
IS  - 802
ER  - 
TY  - JOUR
A1  - Könnecke, Rene
A1  - Follath, R.
A1  - Pontius, N.
A1  - Schlappa, J.
A1  - Eggenstein, F.
A1  - Zeschke, T.
A1  - Bischoff, P.
A1  - Schmidt, J. -S.
A1  - Noll, T.
A1  - Trabant, C.
A1  - Schreck, S.
A1  - Wernet, Ph.
A1  - Eisebitt, S.
A1  - Senf, F.
A1  - Schuessler-Langeheine, Christian
A1  - Erko, A.
A1  - Föhlisch, Alexander
T1  - The confocal plane grating spectrometer at BESSY II
JF  - Journal of electron spectroscopy and related phenomena : the international journal on theoretical and experimental aspects of electron spectroscopy
N2  - At BESSY II a confocal plane grating spectrometer for resonant inelastic X-ray scattering (RIXS) is currently under commissioning. The new endstation operates with a source size of 4 x 1 mu m(2) provided by its dedicated beamline. The RIXS-spectrometer covers an energy range from 50 eV to 1000 eV, providing a resolving power E/Delta E of 5000-15,000. The beamline allows full polarization control and gives a photon flux of up to 7 x 10(14) photons/s/0.1 A/0.1%bandwidth by offering a resolving power E/Delta E of 4000-12,000.
KW  - Resonant inelastic X-ray scattering
KW  - Soft X-ray monochromator
KW  - High transmission micro focus beamline
KW  - Plane grating emission spectrometer
Y1  - 2013
U6  - https://doi.org/10.1016/j.elspec.2012.11.003
SN  - 0368-2048
VL  - 188
SP  - 133
EP  - 139
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Jones, Geraint H.
A1  - Arridge, Christopher S.
A1  - Coates, Andrew J.
A1  - Lewis, Gethyn R.
A1  - Kanani, Sheila
A1  - Wellbrock, Anne
A1  - Young, David T.
A1  - Crary, Frank J.
A1  - Tokar, Robert L.
A1  - Wilson, R. J.
A1  - Hill, Thomas W.
A1  - Johnson, Robert E.
A1  - Mitchell, Donald G.
A1  - Schmidt, Jürgen
A1  - Kempf, Sascha
A1  - Beckmann, Uwe
A1  - Russell, Christopher T.
A1  - Jia, Y. D.
A1  - Dougherty, Michele K.
A1  - Waite, J. Hunter
A1  - Magee, Brian A.
T1  - Fine jet structure of electrically charged grains in Enceladus' plume
N2  - By traversing the plume erupting from high southern latitudes on Saturn's moon Enceladus, Cassini orbiter instruments can directly sample the material therein. Cassini Plasma Spectrometer, CAPS, data show that a major plume component comprises previously-undetected particles of nanometer scales and larger that bridge the mass gap between previously observed gaseous species and solid icy grains. This population is electrically charged both negative and positive, indicating that subsurface triboelectric charging, i.e., contact electrification of condensed plume material may occur through mutual collisions within vents. The electric field of Saturn's magnetosphere controls the jets' morphologies, separating particles according to mass and charge. Fine-scale structuring of these particles' spatial distribution correlates with discrete plume jets' sources, and reveals locations of other possible active regions. The observed plume population likely forms a major component of high velocity nanometer particle streams detected outside Saturn's magnetosphere.
Y1  - 2009
UR  - http://www.agu.org/journals/gl/
U6  - https://doi.org/10.1029/2009gl038284
SN  - 0094-8276
ER  - 
TY  - JOUR
A1  - Arnison, Paul G.
A1  - Bibb, Mervyn J.
A1  - Bierbaum, Gabriele
A1  - Bowers, Albert A.
A1  - Bugni, Tim S.
A1  - Bulaj, Grzegorz
A1  - Camarero, Julio A.
A1  - Campopiano, Dominic J.
A1  - Challis, Gregory L.
A1  - Clardy, Jon
A1  - Cotter, Paul D.
A1  - Craik, David J.
A1  - Dawson, Michael
A1  - Dittmann-Thünemann, Elke
A1  - Donadio, Stefano
A1  - Dorrestein, Pieter C.
A1  - Entian, Karl-Dieter
A1  - Fischbach, Michael A.
A1  - Garavelli, John S.
A1  - Goeransson, Ulf
A1  - Gruber, Christian W.
A1  - Haft, Daniel H.
A1  - Hemscheidt, Thomas K.
A1  - Hertweck, Christian
A1  - Hill, Colin
A1  - Horswill, Alexander R.
A1  - Jaspars, Marcel
A1  - Kelly, Wendy L.
A1  - Klinman, Judith P.
A1  - Kuipers, Oscar P.
A1  - Link, A. James
A1  - Liu, Wen
A1  - Marahiel, Mohamed A.
A1  - Mitchell, Douglas A.
A1  - Moll, Gert N.
A1  - Moore, Bradley S.
A1  - Mueller, Rolf
A1  - Nair, Satish K.
A1  - Nes, Ingolf F.
A1  - Norris, Gillian E.
A1  - Olivera, Baldomero M.
A1  - Onaka, Hiroyasu
A1  - Patchett, Mark L.
A1  - Piel, Jörn
A1  - Reaney, Martin J. T.
A1  - Rebuffat, Sylvie
A1  - Ross, R. Paul
A1  - Sahl, Hans-Georg
A1  - Schmidt, Eric W.
A1  - Selsted, Michael E.
A1  - Severinov, Konstantin
A1  - Shen, Ben
A1  - Sivonen, Kaarina
A1  - Smith, Leif
A1  - Stein, Torsten
A1  - Suessmuth, Roderich D.
A1  - Tagg, John R.
A1  - Tang, Gong-Li
A1  - Truman, Andrew W.
A1  - Vederas, John C.
A1  - Walsh, Christopher T.
A1  - Walton, Jonathan D.
A1  - Wenzel, Silke C.
A1  - Willey, Joanne M.
A1  - van der Donk, Wilfred A.
T1  - Ribosomally synthesized and post-translationally modified peptide natural products overview and recommendations for a universal nomenclature
JF  - Natural product reports : a journal of current developments in bio-organic chemistry
N2  - This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed.
Y1  - 2013
U6  - https://doi.org/10.1039/c2np20085f
SN  - 0265-0568
VL  - 30
IS  - 1
SP  - 108
EP  - 160
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Tobie, G.
A1  - Teanby, N. A.
A1  - Coustenis, A.
A1  - Jaumann, Ralf
A1  - Raulin, E.
A1  - Schmidt, J.
A1  - Carrasco, N.
A1  - Coates, Andrew J.
A1  - Cordier, D.
A1  - De Kok, R.
A1  - Geppert, W. D.
A1  - Lebreton, J. -P.
A1  - Lefevre, A.
A1  - Livengood, T. A.
A1  - Mandt, K. E.
A1  - Mitri, G.
A1  - Nimmo, F.
A1  - Nixon, C. A.
A1  - Norman, L.
A1  - Pappalardo, R. T.
A1  - Postberg, F.
A1  - Rodriguez, S.
A1  - SchuizeMakuch, D.
A1  - Soderblom, J. M.
A1  - Solomonidou, A.
A1  - Stephan, K.
A1  - Stofan, E. R.
A1  - Turtle, E. P.
A1  - Wagner, R. J.
A1  - West, R. A.
A1  - Westlake, J. H.
T1  - Science goals and mission concept for the future exploration of Titan and Enceladus
JF  - Planetary and space science
KW  - Titan
KW  - Enceladus
KW  - Atmosphere
KW  - Surface
KW  - Ocean
KW  - Interior
KW  - Missions
Y1  - 2014
U6  - https://doi.org/10.1016/j.pss.2014.10.002
SN  - 0032-0633
VL  - 104
SP  - 59
EP  - 77
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Schmidt, Robert W.
A1  - Kundic, T.
A1  - Pen, U.-L.
A1  - Wambsganß, Joachim
A1  - Bergeron, L. E.
A1  - Colley, W.
A1  - Corson, C.
A1  - Hastings, N. G.
A1  - Hoyes, T.
A1  - Long, D. C.
A1  - Loomis, K. A.
A1  - Malhotra, S.
A1  - Rhoads, J. E.
A1  - Stanek, K. Z.
T1  - Optical monitoring of the gravitationally lensed quasar Q2237+0305 from APO between June 1995 and January 1998
N2  - We present a data set of images of the gravitationally lensed quasar Q2237+0305, that was obtained at the Apache Point Observatory (APO) between June 1995 and January 1998. Although the images were taken under variable, often poor seeing conditions and with coarse pixel sampling, photometry is possible for the two brighter quasar images A and B with the help of exact quasar image positions from HST observations. We obtain a light curve with 73 data points for each of the images A and B. There is evidence for a long (ga 100 day) brightness peak in image A in 1996 with an amplitude of about 0.4 to 0.5 mag (relative to 1995), which indicates that microlensing has been taking place in the lensing galaxy. Image B does not vary much over the course of the observation period. The long, smooth variation of the light curve is similar to the results from the OGLE monitoring of the system (Wozniak et al. cite{Wozniak00}). Based on observations obtained with the Apache Point Observatory 3.5-meter telescope, which is owned and operated by the Astrophysical Research Consortium.
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Wisotzki, Lutz
A1  - Bacon, R.
A1  - Brinchmann, J.
A1  - Cantalupo, S.
A1  - Richter, Philipp
A1  - Schaye, J.
A1  - Schmidt, Kasper Borello
A1  - Urrutia, Tanya
A1  - Weilbacher, Peter Michael
A1  - Akhlaghi, M.
A1  - Bouche, N.
A1  - Contini, T.
A1  - Guiderdoni, B.
A1  - Herenz, E. C.
A1  - Inami, H.
A1  - Kerutt, Josephine Victoria
A1  - Leclercq, F.
A1  - Marino, R. A.
A1  - Maseda, M.
A1  - Monreal-Ibero, A.
A1  - Nanayakkara, T.
A1  - Richard, J.
A1  - Saust, R.
A1  - Steinmetz, Matthias
A1  - Wendt, Martin
T1  - Nearly all the sky is covered by Lyman-alpha emission around high-redshift galaxies
JF  - Nature : the international weekly journal of science
N2  - Galaxies are surrounded by large reservoirs of gas, mostly hydrogen, that are fed by inflows from the intergalactic medium and by outflows from galactic winds. Absorption-line measurements along the lines of sight to bright and rare background quasars indicate that this circumgalactic medium extends far beyond the starlight seen in galaxies, but very little is known about its spatial distribution. The Lyman-alpha transition of atomic hydrogen at a wavelength of 121.6 nanometres is an important tracer of warm (about 104 kelvin) gas in and around galaxies, especially at cosmological redshifts greater than about 1.6 at which the spectral line becomes observable from the ground. Tracing cosmic hydrogen through its Lyman-a emission has been a long-standing goal of observational astrophysics(1-3), but the extremely low surface brightness of the spatially extended emission is a formidable obstacle. A new window into circumgalactic environments was recently opened by the discovery of ubiquitous extended Lyman-alpha emission from hydrogen around high-redshift galaxies(4,5). Such measurements were previously limited to especially favourable systems(6-8) or to the use of massive statistical averaging(9,10) because of the faintness of this emission. Here we report observations of low-surface-brightness Lyman-alpha emission surrounding faint galaxies at redshifts between 3 and 6. We find that the projected sky coverage approaches 100 per cent. The corresponding rate of incidence (the mean number of Lyman-alpha emitters penetrated by any arbitrary line of sight) is well above unity and similar to the incidence rate of high-column-density absorbers frequently detected in the spectra of distant quasars(11-14). This similarity suggests that most circumgalactic atomic hydrogen at these redshifts has now been detected in emission.
Y1  - 2018
U6  - https://doi.org/10.1038/s41586-018-0564-6
SN  - 0028-0836
SN  - 1476-4687
VL  - 562
IS  - 7726
SP  - 229
EP  - 232
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - CHAP
A1  - Popp, Alexander
A1  - Blaum, Niels
A1  - Domptail, Stephanie
A1  - Herpel, Nicole
A1  - Gröngröft, Alexander
A1  - Hoffman, T. T.
A1  - Jürgens, Norbert
A1  - Milton, Sue
A1  - Nuppenau, Ernst-August
A1  - Rossmanith, Eva
A1  - Schmidt, Michael
A1  - Vogel, Melanie
A1  - Vohland, Katrin
A1  - Jeltsch, Florian
T1  - From satellite imagery to soil-plant interactions
BT  - integrating disciplines and scales in process based simulation models
N2  - Decisions for the conservation of biodiversity and sustainable management of natural resources are typically related to large scales, i.e. the landscape level. However, understanding and predicting the effects of land use and climate change on scales relevant for decision-making requires to include both, large scale vegetation dynamics and small scale processes, such as soil-plant interactions. Integrating the results of multiple BIOTA subprojects enabled us to include necessary data of soil science, botany, socio-economics and remote sensing into a high resolution, process-based and spatially-explicit model. Using an example from a sustainably-used research farm and a communally used and degraded farming area in semiarid southern Namibia we show the power of simulation models as a tool to integrate processes across disciplines and scales.
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-7302
N1  - Interdisziplinäres Zentrum für Musterdynamik und Angewandte Fernerkundung Workshop vom 9. - 10. Februar 2006.

[Poster]
ER  - 
TY  - JOUR
A1  - Christopher Ashwood, Wout Bittremieux
A1  - Bittremieux, Wout
A1  - Deutsch, Eric W.
A1  - Doncheva, Nadezhda T.
A1  - Dorfer, Viktoria
A1  - Gabriels, Ralf
A1  - Gorshkov, Vladimir
A1  - Gupta, Surya
A1  - Jones, Andrew R.
A1  - Käll, Lukas
A1  - Kopczynski, Dominik
A1  - Lane, Lydie
A1  - Lautenbacher, Ludwig
A1  - Legeay, Marc
A1  - Locard-Paulet, Marie
A1  - Mesuere, Bart
A1  - Sachsenberg, Timo
A1  - Salz, Renee
A1  - Samaras, Patroklos
A1  - Schiebenhoefer, Henning
A1  - Schmidt, Tobias
A1  - Schwämmle, Veit
A1  - Soggiu, Alessio
A1  - Uszkoreit, Julian
A1  - Van Den Bossche, Tim
A1  - Van Puyvelde, Bart
A1  - Van Strien, Joeri
A1  - Verschaffelt, Pieter
A1  - Webel, Henry
A1  - Willems, Sander
A1  - Perez-Riverolab, Yasset
A1  - Netz, Eugen
A1  - Pfeuffer, Julianus
T1  - Proceedings of the EuBIC-MS 2020 Developers’ Meeting
JF  - EuPA Open Proteomics
N2  - The 2020 European Bioinformatics Community for Mass Spectrometry (EuBIC-MS) Developers’ meeting was held from January 13th to January 17th 2020 in Nyborg, Denmark. Among the participants were scientists as well as developers working in the field of computational mass spectrometry (MS) and proteomics. The 4-day program was split between introductory keynote lectures and parallel hackathon sessions. During the latter, the participants developed bioinformatics tools and resources addressing outstanding needs in the community. The hackathons allowed less experienced participants to learn from more advanced computational MS experts, and to actively contribute to highly relevant research projects. We successfully produced several new tools that will be useful to the proteomics community by improving data analysis as well as facilitating future research. All keynote recordings are available on https://doi.org/10.5281/zenodo.3890181.
KW  - computational mass spectrometry
KW  - proteomics
KW  - bioinformatics
KW  - spectrum clustering
KW  - phosphoproteomics
KW  - XIC extraction
KW  - proteomics graph networks
KW  - predicted spectra
Y1  - 2020
U6  - https://doi.org/10.1016/j.euprot.2020.11.001
SN  - 2212-9685
VL  - 24
SP  - 1
EP  - 6
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Hegewald, J.
A1  - Schmidt, T.
A1  - Gohs, U.
A1  - Gunther, M.
A1  - Reichelt, R.
A1  - Stiller, Burkhard
A1  - Arndt, K. F.
T1  - Electron beam irradiation of poly(vinyl methyl ether) films : 1. Synthesis and film topography
N2  - Temperature-sensitive hydrogel layers on silicon (Si) substrates were synthesized by electron beam irradiation of spin-coated poly(vinyl methyl ether) (PVME) films. The influences of the used solvent, the polymer concentration, and the spinning velocity on the homogeneity and the thickness of the PVME film were investigated. In the range of concentration c(p) = 1-15 wt% PVME in ethanol solution, homogeneous films with a thickness between d = 50 nm and 1.7 mu m were obtained. The films were cross-linked by electron beam irradiation under inert atmosphere and analyzed by sol-gel- analysis. The results were compared with bulkgels formed by electron beam irradiation of PVME in the dry state. The film topography was analyzed by high-resolution field emission scanning electron microscopy and atomic force microscopy. An islandlike structure in the dry, swollen, and shrunken state of the hydrogel films was observed
Y1  - 2005
SN  - 0743-7463
ER  - 
TY  - JOUR
A1  - Goldmann, Daniela
A1  - Nordsieck, A.
A1  - Janietz, Dietmar
A1  - Frese, T.
A1  - Schmidt, C.
A1  - Wendorff, Joachim Heinz
T1  - Smectic and columnar liquid crystalline phases through charge-transfer interactions
N2  - New heterocyclic electron donors based on. a 1,3,5-triazine nucleus are presented. Three phenyl rings are grafted to the triazine core either via secondary amino groups or by a direct C,C-linkage and a specific number of decyloxy chains is attached to the molecular periphery. The compounds are non-liquid crystalline in their pure states. Lamellar or columnar mesophases are induced by attractive interactions with electron acceptors
Y1  - 2004
SN  - 1058-725X
ER  - 
TY  - JOUR
A1  - Walz, Ariane
A1  - Schmidt, Katja
A1  - Ruiz-Frau, Ana
A1  - Nicholas, Kimberly A.
A1  - Bierry, Adeline
A1  - Lentsch, Aster de Vries
A1  - Dyankov, Apostol
A1  - Joyce, Deirdre
A1  - Liski, Anja H.
A1  - Marba, Nuria
A1  - Rosario, Ines T.
A1  - Scholte, Samantha S. K.
T1  - Sociocultural valuation of ecosystem services for operational ecosystem management: mapping applications by decision contexts in Europe
JF  - Regional environmental change
N2  - Sociocultural valuation (SCV) of ecosystem services (ES) discloses the principles, importance or preferences expressed by people towards nature. Although ES research has increasingly addressed sociocultural values in past years, little effort has been made to systematically review the components of sociocultural valuation applications for different decision contexts (i.e. awareness raising, accounting, priority setting, litigation and instrument design). In this analysis, we investigate the characteristics of 48 different sociocultural valuation applications—characterised by unique combinations of decision context, methods, data collection formats and participants—across ten European case studies. Our findings show that raising awareness for the sociocultural value of ES by capturing people’s perspective and establishing the status quo, was found the most frequent decision context in case studies, followed by priority setting and instrument development. Accounting and litigation issues were not addressed in any of the applications. We reveal that applications for particular decision contexts are methodologically similar, and that decision contexts determine the choice of methods, data collection formats and participants involved. Therefore, we conclude that understanding the decision context is a critical first step to designing and carrying out fit-for-purpose sociocultural valuation of ES in operational ecosystem management.
KW  - Sociocultural valuation
KW  - Ecosystem services
KW  - Local-to-regional scale
KW  - Operational use
Y1  - 2019
U6  - https://doi.org/10.1007/s10113-019-01506-7
SN  - 1436-3798
SN  - 1436-378X
VL  - 19
IS  - 8
SP  - 2245
EP  - 2259
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Qin, Qing
A1  - Heil, T.
A1  - Schmidt, J.
A1  - Schmallegger, Max
A1  - Gescheidt, Georg
A1  - Antonietti, Markus
A1  - Oschatz, Martin
T1  - Electrochemical Fixation of Nitrogen and Its Coupling with Biomass Valorization with a Strongly Adsorbing and Defect Optimized Boron-Carbon-Nitrogen Catalyst
JF  - ACS Applied Energy Materials
N2  - The electrochemical conversion of low-cost precursors into high-value chemicals using renewably generated electricity is a promising approach to build up an environmentally friendly energy cycle, including a storage element. The large-scale implementation of such process can, however, only be realized by the design of cost-effective electrocatalysts with high efficiency and highest stability. Here, we report the synthesis of N and B codoped porous carbons. The constructed B-N motives combine abundant unpaired electrons and frustrated Lewis pairs (FLPs). They result in desirable performance for electrochemical N-2 reduction reaction (NRR) and electrooxidation of 5-hydroxymethylfurfural (HMF) in the absence of any metal cocatalyst. A maximum Faradaic efficiency of 15.2% with a stable NH3 production rate of 21.3 mu g h(-1) mg(-1) is obtained in NRR. Besides, 2,5-furandicarboxylic acid (FDCA) is first obtained by using non-metalbased electrocatalysts at a conversion of 71% and with yield of 57%. Gas adsorption experiments elucidate the relationship between the structure and the ability of the catalysts to activate the substrate molecules. This work opens up deep insights for the rational design of non-metal-based catalysts for potential electrocatalytic applications and the possible enhancement of their activity by the introduction of FLPs and point defects at grain boundaries.
KW  - non-metal catalysis
KW  - porous carbon
KW  - heteroatoms
KW  - N-2 reduction
KW  - HMF oxidation
Y1  - 2019
U6  - https://doi.org/10.1021/acsaem.9b01852
SN  - 2574-0962
VL  - 2
IS  - 11
SP  - 8359
EP  - 8365
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Tötzke, Christian
A1  - Gaiselmann, G.
A1  - Osenberg, M.
A1  - Arlt, T.
A1  - Markötter, H.
A1  - Hilger, A.
A1  - Kupsch, Andreas
A1  - Müller, B. R.
A1  - Schmidt, V.
A1  - Lehnert, W.
A1  - Manke, Ingo
T1  - Influence of hydrophobic treatment on the structure of compressed gas diffusion layers
JF  - Journal of power sources : the international journal on the science and technology of electrochemical energy systems
N2  - Carbon fiber based felt materials are widely used as gas diffusion layer (GDL) in fuel cells. Their transport properties can be adjusted by adding hydrophobic agents such as polytetrafluoroethylene (PTFE). We present a synchrotron X-ray tomographic study on the felt material Freudenberg H2315 with different PIPE finishing. In this study, we analyze changes in microstructure and shape of GDLs at increasing degree of compression which are related to their specific PTFE load. A dedicated compression device mimicking the channel-land pattern of the flowfield is used to reproduce the inhomogeneous compression found in a fuel cell. Transport relevant geometrical parameters such as porosity, pore size distribution and geometric tortuosity are calculated and consequences for media transport discussed. PTFE finishing results in a marked change of shape of compressed GDLs: surface is smoothed and the invasion of GDL fibers into the flow field channel strongly mitigated. Furthermore, the PTFE impacts the microstructure of the compressed GDL. The number of available wide transport paths is significantly increased as compared to the untreated material. These changes improve the transport capacity liquid water through the GDL and promote the discharge of liquid water droplets from the cell. (C) 2016 Elsevier B.V. All rights reserved.
KW  - Gas diffusion layer
KW  - Synchrotron tomography
KW  - Compression
KW  - Hydrophobic treatment
KW  - Water transport
Y1  - 2016
U6  - https://doi.org/10.1016/j.jpowsour.2016.05.118
SN  - 0378-7753
SN  - 1873-2755
VL  - 324
SP  - 625
EP  - 636
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Sachse, Dirk
A1  - Billault, Isabelle
A1  - Bowen, Gabriel J.
A1  - Chikaraishi, Yoshito
A1  - Dawson, Todd E.
A1  - Feakins, Sarah J.
A1  - Freeman, Katherine H.
A1  - Magill, Clayton R.
A1  - McInerney, Francesca A.
A1  - van der Meer, Marcel T. J.
A1  - Polissar, Pratigya
A1  - Robins, Richard J.
A1  - Sachs, Julian P.
A1  - Schmidt, Hanns-Ludwig
A1  - Sessions, Alex L.
A1  - White, James W. C.
A1  - West, Jason B.
A1  - Kahmen, Ansgar
ED  - Jeanloz, R
T1  - Molecular Paleohydrology interpreting the Hydrogen- Isotopic Composition of Lipid Biomarkers from Photosynthesizing Organisms
JF  - Annual review of earth and planetary sciences
JF  - Annual Review of Earth and Planetary Sciences
N2  - Hydrogen-isotopic abundances of lipid biomarkers are emerging as important proxies in the study of ancient environments and ecosystems. A decade ago, pioneering studies made use of new analytical methods and demonstrated that the hydrogen-isotopic composition of individual lipids from aquatic and terrestrial organisms can be related to the composition of their growth (i.e., environmental) water. Subsequently, compound-specific deuterium/hydrogen (D/H) ratios of sedimentary biomarkers have been increasingly used as paleohydrological proxies over a range of geological timescales. Isotopic fractionation observed between hydrogen in environmental water and hydrogen in lipids, however, is sensitive to biochemical, physiological, and environmental influences on the composition of hydrogen available for biosynthesis in cells. Here we review the factors and processes that are known to influence the hydrogen-isotopic compositions of lipids-especially n-alkanes-from photosynthesizing organisms, and we provide a framework for interpreting their D/H ratios from ancient sediments and identify future research opportunities.
KW  - paleoclimate
KW  - paleoclimate proxy
KW  - deuterium
KW  - organic geochemistry
Y1  - 2012
SN  - 978-0-8243-2040-9
U6  - https://doi.org/10.1146/annurev-earth-042711-105535
SN  - 0084-6597
VL  - 40
IS  - 1
SP  - 221
EP  - 249
PB  - Annual Reviews
CY  - Palo Alto
ER  - 
TY  - JOUR
A1  - Pedatella, Nick M.
A1  - Fang, T. -W.
A1  - Jin, Hao
A1  - Sassi, F.
A1  - Schmidt, H.
A1  - Chau, Jorge Luis
A1  - Siddiqui, Tarique Adnan
A1  - Goncharenko, L.
T1  - Multimodel comparison of the ionosphere variability during the 2009 sudden stratosphere warming
JF  - Journal of geophysical research : Space physics
N2  - A comparison of different model simulations of the ionosphere variability during the 2009 sudden stratosphere warming (SSW) is presented. The focus is on the equatorial and low-latitude ionosphere simulated by the Ground-to-topside model of the Atmosphere and Ionosphere for Aeronomy (GAIA), Whole Atmosphere Model plus Global Ionosphere Plasmasphere (WAM+GIP), and Whole Atmosphere Community Climate Model eXtended version plus Thermosphere-Ionosphere-Mesosphere-Electrodynamics General Circulation Model (WACCMX+TIMEGCM). The simulations are compared with observations of the equatorial vertical plasma drift in the American and Indian longitude sectors, zonal mean Fregion peak density (NmF2) from the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) satellites, and ground-based Global Positioning System (GPS) total electron content (TEC) at 75 degrees W. The model simulations all reproduce the observed morning enhancement and afternoon decrease in the vertical plasma drift, as well as the progression of the anomalies toward later local times over the course of several days. However, notable discrepancies among the simulations are seen in terms of the magnitude of the drift perturbations, and rate of the local time shift. Comparison of the electron densities further reveals that although many of the broad features of the ionosphere variability are captured by the simulations, there are significant differences among the different model simulations, as well as between the simulations and observations. Additional simulations are performed where the neutral atmospheres from four different whole atmosphere models (GAIA, HAMMONIA (Hamburg Model of the Neutral and Ionized Atmosphere), WAM, and WACCMX) provide the lower atmospheric forcing in the TIME-GCM. These simulations demonstrate that different neutral atmospheres, in particular, differences in the solar migrating semidiurnal tide, are partly responsible for the differences in the simulated ionosphere variability in GAIA, WAM+GIP, and WACCMX+TIMEGCM.
KW  - ionosphere
KW  - sudden stratosphere warming
Y1  - 2016
U6  - https://doi.org/10.1002/2016JA022859
SN  - 2169-9380
SN  - 2169-9402
VL  - 121
SP  - 7204
EP  - 7225
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Wambsganß, Joachim
A1  - Schmidt, Robert W.
A1  - Colley, W.
A1  - Kundic, T.
A1  - Turner, E. L.
T1  - Microlensing results from APO monitoring of the double quasar Q0957+561A,B between 1995 and 1998
N2  - If the halo of the lensing galaxy 0957+561 is made of massive compact objects (MACHOs), they must affect the lightcurves of the quasar images Q0957+561 A and B differently. We search for this microlensing effect in the double quasar by comparing monitoring data for the two images A and B - obtained with the 3.5m Apache Point Observatory from 1995 to 1998 - with intensive numerical simulations. This way we test whether the halo of the lensing galaxy can be made of MACHOs of various masses. We can exclude a halo entirely made out of MACHOs with masses between 10-6 Msun and 10-2 Msun for quasar sizes of less than 3x 1014 h60-1/2 cm, hereby extending previous limits upwards by one order of magnitude.
Y1  - 2000
ER  - 
TY  - JOUR
A1  - van Rees, Charles B.
A1  - Waylen, Kerry A.
A1  - Schmidt-Kloiber, Astrid
A1  - Thackeray, Stephen J.
A1  - Kalinkat, Gregor
A1  - Martens, Koen
A1  - Domisch, Sami
A1  - Lillebo, Ana
A1  - Hermoso, Virgilio
A1  - Grossart, Hans-Peter
A1  - Schinegger, Rafaela
A1  - Decleer, Kris
A1  - Adriaens, Tim
A1  - Denys, Luc
A1  - Jaric, Ivan
A1  - Janse, Jan H.
A1  - Monaghan, Michael T.
A1  - De Wever, Aaike
A1  - Geijzendorffer, Ilse
A1  - Adamescu, Mihai C.
A1  - Jähnig, Sonja C.
T1  - Safeguarding freshwater life beyond 2020
BT  - recommendations for the new global biodiversity framework from the European experience
JF  - Conservation letters
N2  - Plans are currently being drafted for the next decade of action on biodiversity-both the post-2020 Global Biodiversity Framework of the Convention on Biological Diversity (CBD) and Biodiversity Strategy of the European Union (EU). Freshwater biodiversity is disproportionately threatened and underprioritized relative to the marine and terrestrial biota, despite supporting a richness of species and ecosystems with their own intrinsic value and providing multiple essential ecosystem services. Future policies and strategies must have a greater focus on the unique ecology of freshwater life and its multiple threats, and now is a critical time to reflect on how this may be achieved. We identify priority topics including environmental flows, water quality, invasive species, integrated water resources management, strategic conservation planning, and emerging technologies for freshwater ecosystem monitoring. We synthesize these topics with decades of first-hand experience and recent literature into 14 special recommendations for global freshwater biodiversity conservation based on the successes and setbacks of European policy, management, and research. Applying and following these recommendations will inform and enhance the ability of global and European post-2020 biodiversity agreements to halt and reverse the rapid global decline of freshwater biodiversity.
KW  - climate change
KW  - conservation
KW  - ecosystem services
KW  - rivers
KW  - sustainable
KW  - development goals
KW  - water resources
KW  - wetlands
Y1  - 2020
U6  - https://doi.org/10.1111/conl.12771
SN  - 1755-263X
VL  - 14
IS  - 1
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Spallanzani, Roberta
A1  - Koga, Kenneth T.
A1  - Cichy, Sarah B.
A1  - Wiedenbeck, Michael
A1  - Schmidt, Burkhard C.
A1  - Oelze, Marcus
A1  - Wilke, Max
T1  - Lithium and boron diffusivity and isotopic fractionation in hydrated rhyolitic melts
JF  - Contributions to mineralogy and petrology
N2  - Lithium and boron are trace components of magmas, released during exsolution of a gas phase during volcanic activity. 
In this study, we determine the diffusivity and isotopic fractionation of Li and B in hydrous silicate melts. 
Two glasses were synthesized with the same rhyolitic composition (4.2 wt% water), having different Li and B contents; these were studied in diffusion-couple experiments that were performed using an internally heated pressure vessel, operated at 300 MPa in the temperature range 700-1250 degrees C for durations from 0 s to 24 h. From this we determined activation energies for Li and B diffusion of 57 +/- 4 kJ/mol and 152 +/- 15 kJ/mol with pre-exponential factors of 1.53 x 10(-7) m(2)/s and 3.80 x 10(-8) m(2)/s, respectively.
Lithium isotopic fractionation during diffusion gave beta values between 0.15 and 0.20, whereas B showed no clear isotopic fractionation. 

Our Li diffusivities and isotopic fractionation results differ somewhat from earlier published values, but overall confirm that Li diffusivity increases with water content. Our results on B diffusion show that similarly to Li, B mobility increases in the presence of water. 
By applying the Eyring relation, we confirm that B diffusivity is limited by viscous flow in silicate melts. 

Our results on Li and B diffusion present a new tool for understanding degassing-related processes, offering a potential geospeedometer to measure volcanic ascent rates.
KW  - stable isotopes
KW  - diffusion
KW  - isotopic fractionation
KW  - hydrated silicate
KW  - melts
Y1  - 2022
U6  - https://doi.org/10.1007/s00410-022-01937-2
SN  - 0010-7999
SN  - 1432-0967
VL  - 177
IS  - 8
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Darwall, William
A1  - Bremerich, Vanessa
A1  - De Wever, Aaike
A1  - Dell, Anthony I.
A1  - Freyhof, Joerg
A1  - Gessner, Mark O.
A1  - Grossart, Hans-Peter
A1  - Harrison, Ian
A1  - Irvine, Ken
A1  - Jähnig, Sonja C.
A1  - Jeschke, Jonathan M.
A1  - Lee, Jessica J.
A1  - Lu, Cai
A1  - Lewandowska, Aleksandra M.
A1  - Monaghan, Michael T.
A1  - Nejstgaard, Jens C.
A1  - Patricio, Harmony
A1  - Schmidt-Kloiber, Astrid
A1  - Stuart, Simon N.
A1  - Thieme, Michele
A1  - Tockner, Klement
A1  - Turak, Eren
A1  - Weyl, Olaf
T1  - The alliance for freshwater life
BT  - a global call to unite efforts for freshwater biodiversity science and conservation
JF  - Aquatic Conservation: Marine and Freshwater Ecosystems
N2  - 1. Global pressures on freshwater ecosystems are high and rising. Viewed primarily as a resource for humans, current practices of water use have led to catastrophic declines in freshwater species and the degradation of freshwater ecosystems, including their genetic and functional diversity. Approximately three-quarters of the world's inland wetlands have been lost, one-third of the 28 000 freshwater species assessed for the International Union for Conservation of Nature (IUCN) Red List are threatened with extinction, and freshwater vertebrate populations are undergoing declines that are more rapid than those of terrestrial and marine species. This global loss continues unchecked, despite the importance of freshwater ecosystems as a source of clean water, food, livelihoods, recreation, and inspiration.

2.  The causes of these declines include hydrological alterations, habitat degradation and loss, overexploitation, invasive species, pollution, and the multiple impacts of climate change. Although there are policy initiatives that aim to protect freshwater life, these are rarely implemented with sufficient conviction and enforcement. Policies that focus on the development and management of fresh waters as a resource for people almost universally neglect the biodiversity that they contain.

3. Here we introduce the Alliance for Freshwater Life, a global initiative, uniting specialists in research, data synthesis, conservation, education and outreach, and policymaking. This expert network aims to provide the critical mass required for the effective representation of freshwater biodiversity at policy meetings, to develop solutions balancing the needs of development and conservation, and to better convey the important role freshwater ecosystems play in human well-being. Through this united effort we hope to reverse this tide of loss and decline in freshwater biodiversity. We introduce several short- and medium-term actions as examples for making positive change, and invite individuals, organizations, authorities, and governments to join the Alliance for Freshwater Life.
KW  - biodiversity
KW  - conservation evaluation
KW  - endangered species
KW  - fish
KW  - invertebrates
KW  - macrophytes
Y1  - 2018
U6  - https://doi.org/10.1002/aqc.2958
SN  - 1052-7613
SN  - 1099-0755
VL  - 28
IS  - 4
SP  - 1015
EP  - 1022
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Tucker, Marlee A.
A1  - Boehning-Gaese, Katrin
A1  - Fagan, William F.
A1  - Fryxell, John M.
A1  - Van Moorter, Bram
A1  - Alberts, Susan C.
A1  - Ali, Abdullahi H.
A1  - Allen, Andrew M.
A1  - Attias, Nina
A1  - Avgar, Tal
A1  - Bartlam-Brooks, Hattie
A1  - Bayarbaatar, Buuveibaatar
A1  - Belant, Jerrold L.
A1  - Bertassoni, Alessandra
A1  - Beyer, Dean
A1  - Bidner, Laura
A1  - van Beest, Floris M.
A1  - Blake, Stephen
A1  - Blaum, Niels
A1  - Bracis, Chloe
A1  - Brown, Danielle
A1  - de Bruyn, P. J. Nico
A1  - Cagnacci, Francesca
A1  - Calabrese, Justin M.
A1  - Camilo-Alves, Constanca
A1  - Chamaille-Jammes, Simon
A1  - Chiaradia, Andre
A1  - Davidson, Sarah C.
A1  - Dennis, Todd
A1  - DeStefano, Stephen
A1  - Diefenbach, Duane
A1  - Douglas-Hamilton, Iain
A1  - Fennessy, Julian
A1  - Fichtel, Claudia
A1  - Fiedler, Wolfgang
A1  - Fischer, Christina
A1  - Fischhoff, Ilya
A1  - Fleming, Christen H.
A1  - Ford, Adam T.
A1  - Fritz, Susanne A.
A1  - Gehr, Benedikt
A1  - Goheen, Jacob R.
A1  - Gurarie, Eliezer
A1  - Hebblewhite, Mark
A1  - Heurich, Marco
A1  - Hewison, A. J. Mark
A1  - Hof, Christian
A1  - Hurme, Edward
A1  - Isbell, Lynne A.
A1  - Janssen, Rene
A1  - Jeltsch, Florian
A1  - Kaczensky, Petra
A1  - Kane, Adam
A1  - Kappeler, Peter M.
A1  - Kauffman, Matthew
A1  - Kays, Roland
A1  - Kimuyu, Duncan
A1  - Koch, Flavia
A1  - Kranstauber, Bart
A1  - LaPoint, Scott
A1  - Leimgruber, Peter
A1  - Linnell, John D. C.
A1  - Lopez-Lopez, Pascual
A1  - Markham, A. Catherine
A1  - Mattisson, Jenny
A1  - Medici, Emilia Patricia
A1  - Mellone, Ugo
A1  - Merrill, Evelyn
A1  - Mourao, Guilherme de Miranda
A1  - Morato, Ronaldo G.
A1  - Morellet, Nicolas
A1  - Morrison, Thomas A.
A1  - Diaz-Munoz, Samuel L.
A1  - Mysterud, Atle
A1  - Nandintsetseg, Dejid
A1  - Nathan, Ran
A1  - Niamir, Aidin
A1  - Odden, John
A1  - Oliveira-Santos, Luiz Gustavo R.
A1  - Olson, Kirk A.
A1  - Patterson, Bruce D.
A1  - de Paula, Rogerio Cunha
A1  - Pedrotti, Luca
A1  - Reineking, Bjorn
A1  - Rimmler, Martin
A1  - Rogers, Tracey L.
A1  - Rolandsen, Christer Moe
A1  - Rosenberry, Christopher S.
A1  - Rubenstein, Daniel I.
A1  - Safi, Kamran
A1  - Said, Sonia
A1  - Sapir, Nir
A1  - Sawyer, Hall
A1  - Schmidt, Niels Martin
A1  - Selva, Nuria
A1  - Sergiel, Agnieszka
A1  - Shiilegdamba, Enkhtuvshin
A1  - Silva, Joao Paulo
A1  - Singh, Navinder
A1  - Solberg, Erling J.
A1  - Spiegel, Orr
A1  - Strand, Olav
A1  - Sundaresan, Siva
A1  - Ullmann, Wiebke
A1  - Voigt, Ulrich
A1  - Wall, Jake
A1  - Wattles, David
A1  - Wikelski, Martin
A1  - Wilmers, Christopher C.
A1  - Wilson, John W.
A1  - Wittemyer, George
A1  - Zieba, Filip
A1  - Zwijacz-Kozica, Tomasz
A1  - Mueller, Thomas
T1  - Moving in the Anthropocene
BT  - global reductions in terrestrial mammalian movements
JF  - Science
N2  - Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, we found that movements of mammals in areas with a comparatively high human footprint were on average one-half to one-third the extent of their movements in areas with a low human footprint. We attribute this reduction to behavioral changes of individual animals and to the exclusion of species with long-range movements from areas with higher human impact. Global loss of vagility alters a key ecological trait of animals that affects not only population persistence but also ecosystem processes such as predator-prey interactions, nutrient cycling, and disease transmission.
Y1  - 2018
U6  - https://doi.org/10.1126/science.aam9712
SN  - 0036-8075
SN  - 1095-9203
VL  - 359
IS  - 6374
SP  - 466
EP  - 469
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  -