TY - JOUR A1 - Mikolaj, Michal A1 - Güntner, Andreas A1 - Brunini, Claudio A1 - Wziontek, Hartmut A1 - Gende, Mauricio A1 - Schröder, Stephan A1 - Cassino, Augusto M. A1 - Pasquare, Alfredo A1 - Reich, Marvin A1 - Hartmann, Anne A1 - Oreiro, Fernando Ariel A1 - Pendiuk, Jonathan A1 - Guarracino, Luis A1 - Antokoletz, Ezequiel D. T1 - Hydrometeorological and gravity signals at the Argentine-German Geodetic Observatory (AGGO) in La Plata JF - Earth system science data N2 - The Argentine-German Geodetic Observatory (AGGO) is one of the very few sites in the Southern Hemisphere equipped with comprehensive cutting-edge geodetic instrumentation. The employed observation techniques are used for a wide range of geophysical applications. The data set provides gravity time series and selected gravity models together with the hydrometeorological monitoring data of the observatory. These parameters are of great interest to the scientific community, e.g. for achieving accurate realization of terrestrial and celestial reference frames. Moreover, the availability of the hydrometeorological products is beneficial to inhabitants of the region as they allow for monitoring of environmental changes and natural hazards including extreme events. The hydrological data set is composed of time series of groundwater level, modelled and observed soil moisture content, soil temperature, and physical soil properties and aquifer properties. The meteorological time series include air temperature, humidity, pressure, wind speed, solar radiation, precipitation, and derived reference evapotranspiration. These data products are extended by gravity models of hydrological, oceanic, La Plata estuary, and atmospheric effects. The quality of the provided meteorological time series is tested via comparison to the two closest WMO (World Meteorological Organization) sites where data are available only in an inferior temporal resolution. The hydrological series are validated by comparing the respective forward-modelled gravity effects to independent gravity observations reduced up to a signal corresponding to local water storage variation. Most of the time series cover the time span between April 2016 and November 2018 with either no or only few missing data points. The data set is available at https://doi.org/10.588/GFZ.5.4.2018.001 (Mikolaj et al., 2018). Y1 - 2019 U6 - https://doi.org/10.5194/essd-11-1501-2019 SN - 1866-3508 SN - 1866-3516 VL - 11 IS - 4 SP - 1501 EP - 1513 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Sechi, Antonio A1 - Freitas, Joana M. G. A1 - Wünnemann, Patrick A1 - Töpel, Alexander A1 - Paschoalin, Rafaella Takehara A1 - Ullmann, Sabrina A1 - Schröder, Ricarda A1 - Aydin, Gülcan A1 - Rütten, Stephan A1 - Böker, Alexander A1 - Zenke, Martin A1 - Pich, Andrij T1 - Surface-Grafted Nanogel Arrays Direct Cell Adhesion and Motility JF - Advanced materials interfaces N2 - It has long been appreciated that material chemistry and topology profoundly affect cell adhesion and migration. Here, aqueous poly(N- isopropyl acrylamide) nanogels are designed, synthesized and printed in form of colloidal arrays on glass substrates using wrinkled polydimethylsiloxane templates. Using low-temperature plasma treatment, nanogels are chemically grafted onto glass supports thus leading to highly stable nanogel layers in cell culture media. Liquid cell atomic force microscopy investigations show that surface-grafted nanogels retain their swelling behavior in aqueous media and that extracellular matrix protein coating do not alter their stability and topography. It is demonstrated that surface-grafted nanogels could serve as novel substrates for the analysis of cell adhesion and migration. Nanogels influence size, speed, and dynamics of focal adhesions and cell motility forcing cells to move along highly directional trajectories. Moreover, modulation of nanogel state or spacing serves as an effective tool for regulation of cell motility. It is suggested that nanogel arrays deposited on solid surfaces could be used to provide a precise and tunable system to understand and control cell migration. Additionally, such nanogel arrays will contribute to the development of implantable systems aimed at supporting and enhancing cell migration during, for instance, wound healing and tissue regeneration. Y1 - 2016 U6 - https://doi.org/10.1002/admi.201600455 SN - 2196-7350 VL - 3 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Klann-Delius, Gisela A1 - Kauschke, Christina A1 - Glück, Christian W. A1 - Schröder, Astrid A1 - Lorenz, Antje A1 - Domahs, Frank A1 - Grande, Marion A1 - Domahs, Ulrike A1 - Frankenberg, Jenny v. A1 - Wahl, Michael A1 - De Kok, Dörte A1 - Stadie, Nicole A1 - Machleb, Franziska A1 - Manz, Katrin A1 - Frank, Ulrike A1 - Sperlich, Kathrin A1 - Vauth, Friederike A1 - Hampel, Pamela A1 - Mäder, Mark A1 - Sticher, Heike A1 - Bethmann, Anja A1 - Fischenich, Andrea A1 - Scheich, Henning A1 - Brechmann, André A1 - Peschke, Claudia A1 - Ziegler, Wolfram A1 - Kappes, Juliane A1 - Baumgärtner, Annette A1 - Sonntag, Kristin A1 - Bartels, Luise A1 - Heide, Judith A1 - Meinunger, André A1 - Burchert, Frank A1 - Bohn, Christiane A1 - Kliegl, Reinhold A1 - Gottal, Stephanie A1 - Berendes, Karin A1 - Grabherr, Britta A1 - Schneeberg, Jennifer A1 - Wittler, Marion A1 - Ptok, Martin A1 - Sallat, Stephan ED - Wahl, Michael ED - Michael, Judith ED - Hanne, Sandra T1 - Spektrum Patholinguistik = Schwerpunktthema: der Erwerb von Lexikon und Semantik: Meilensteine, Störungen und Therapie ; Tagungsband zum 1. Herbsttreffen Patholinguistik, 24. November 2007 N2 - Der vorliegende Tagungsband enthält alle Beiträge des 1. Herbsttreffens Patholinguistik, das am 24.11.2007 an der Universität Potsdam stattgefunden hat. Sowohl die drei Hauptvorträge zum Thema „Der Erwerb von Lexikon und Semantik – Meilensteine, Störungen und Therapie“ als auch die Kurzvorträge promovierter Patholinguisten sind ausführlich dokumentiert. Außerdem enthält der Tagungsband die Abstracts der präsentierten Poster. N2 - These proceedings contain the contributions presented at the “1st Herbsttreffen Patholinguistik” that took place on November 24, 2007 at the University of Potsdam. Three main lectures focused on "The acquisition of lexicon and semantics - milestones, impairments, and intervention". In addition, the proceedings contain short presentations on patholinguistic research and the abstracts of the presented posters. T3 - Spektrum Patholinguistik - 1 KW - Patholinguistik KW - Spracherwerb KW - Sprachtherapie KW - lexikalisch-semantische Störungen KW - Sprachentwicklungsstörung (SES) KW - patholinguistics KW - language acquisition KW - speech and language therapy KW - impairments of lexicon and semantics KW - specific language impairment (SLI) Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-18688 SN - 1869-3822 SN - 1866-9433 IS - 1 PB - Universitätsverlag Potsdam CY - Potsdam ER -