TY  - JOUR
A1  - Engel, Tilman
A1  - Schraplau, Anne
A1  - Wochatz, Monique
A1  - Kopinski, Stephan
A1  - Sonnenburg, Dominik
A1  - Schomöller, Anne
A1  - Risch, Lucie
A1  - Kaplick, Hannes
A1  - Mayer, Frank
T1  - Feasability of An Eccentric Isokinetic Protocol to Induce Trunk Muscle Damage: A Pilot Study
JF  - Sports Medicine International Open
N2  - Eccentric exercise is discussed as a treatment option for clinical populations, but specific responses in terms of muscle damage and systemic inflammation after repeated loading of large muscle groups have not been conclusively characterized. Therefore, this study tested the feasibility of an isokinetic protocol for repeated maximum eccentric loading of the trunk muscles. Nine asymptomatic participants (5 f/4 m; 34±6 yrs; 175±13 cm; 76±17 kg) performed three isokinetic 2-minute all-out trunk strength tests (1x concentric (CON), 2x eccentric (ECC1, ECC2), 2 weeks apart; flexion/extension, 60°/s, ROM 55°). Outcomes were peak torque, torque decline, total work, and indicators of muscle damage and inflammation (over 168 h). Statistics were done using the Friedman test (Dunn’s post-test). For ECC1 and ECC2, peak torque and total work were increased and torque decline reduced compared to CON. Repeated ECC bouts yielded unaltered torque and work outcomes. Muscle damage markers were highest after ECC1 (soreness 48 h, creatine kinase 72 h; p<0.05). Their overall responses (area under the curve) were abolished post-ECC2 compared to post-ECC1 (p<0.05). Interleukin-6 was higher post-ECC1 than CON, and attenuated post-ECC2 (p>0.05). Interleukin-10 and tumor necrosis factor-α were not detectable. All markers showed high inter-individual variability. The protocol was feasible to induce muscle damage indicators after exercising a large muscle group, but the pilot results indicated only weak systemic inflammatory responses in asymptomatic adults.
KW  - exercise
KW  - eccentric
KW  - muscle fatigue
KW  - trunk muscles
KW  - isokinetics
KW  - repeated bout effect
KW  - inflammation
KW  - exercise induced muscle damage
KW  - interleukin-6
KW  - internleukin-10
KW  - tumor necrosis factor-α
Y1  - 2021
U6  - https://doi.org/10.1055/a-1757-6724
SN  - 2367-1890
VL  - 6
SP  - E9
EP  - E17
PB  - Thieme
CY  - Stuttgart
ET  - 1
ER  - 
TY  - CHAP
A1  - Scharhag, Jürgen
A1  - Hotzkow, Kristin
A1  - Kopinski, Stephan
A1  - Barche, Martin
A1  - Mayer, Frank
T1  - Echocardiographic 3d speckle tracking values on cardiac wall motion in elite adult, adolescent and pediatric athletes
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2012
SN  - 0195-9131
VL  - 44
SP  - 241
EP  - 241
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - CHAP
A1  - Engel, Tilman
A1  - Kopinski, Stephan
A1  - Carlsohn, Anja
A1  - Cassel, Michael
A1  - Mayer, Frank
T1  - Correlation of sonographic subcutaneous adipose tissue measurements with air displacement plethysmography and calipermetry
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2014
SN  - 0195-9131
SN  - 1530-0315
VL  - 46
IS  - 5
SP  - 539
EP  - 539
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  -