TY  - JOUR
A1  - Frodl, Thomas
A1  - Janowitz, Deborah
A1  - Schmaal, Lianne
A1  - Tozzi, Leonardo
A1  - Dobrowolny, Henrik
A1  - Stein, Dan J.
A1  - Veltman, Dick J.
A1  - Wittfeld, Katharina
A1  - van Erp, Theo G. M.
A1  - Jahanshad, Neda
A1  - Block, Andrea
A1  - Hegenscheid, Katrin
A1  - Voelzke, Henry
A1  - Lagopoulos, Jim
A1  - Hatton, Sean N.
A1  - Hickie, Ian B.
A1  - Frey, Eva Maria
A1  - Carballedo, Angela
A1  - Brooks, Samantha J.
A1  - Vuletic, Daniella
A1  - Uhlmann, Anne
A1  - Veer, Ilya M.
A1  - Walter, Henrik
A1  - Schnell, Knut
A1  - Grotegerd, Dominik
A1  - Arolt, Volker
A1  - Kugel, Harald
A1  - Schramm, Elisabeth
A1  - Konrad, Carsten
A1  - Zurowski, Bartosz
A1  - Baune, Bernhard T.
A1  - van der Wee, Nic J. A.
A1  - van Tol, Marie-Jose
A1  - Penninx, Brenda W. J. H.
A1  - Thompson, Paul M.
A1  - Hibar, Derrek P.
A1  - Dannlowski, Udo
A1  - Grabe, Hans J.
T1  - Childhood adversity impacts on brain subcortical structures relevant to depression
JF  - Journal of psychiatric research
N2  - Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of the present study was to investigate whether childhood adversity is associated with subcortical volumes and how it interacts with a diagnosis of MDD and sex. Within the ENIGMA-MDD network, nine university partner sites, which assessed childhood adversity and magnetic resonance imaging in patients with MDD and controls, took part in the current joint mega-analysis. In this largest effort world-wide to identify subcortical brain structure differences related to childhood adversity, 3036 participants were analyzed for subcortical brain volumes using FreeSurfer. A significant interaction was evident between childhood adversity, MDD diagnosis, sex, and region. Increased exposure to childhood adversity was associated with smaller caudate volumes in females independent of MDD. All subcategories of childhood adversity were negatively associated with caudate volumes in females - in particular emotional neglect and physical neglect (independently from age, ICV, imaging site and MDD diagnosis). There was no interaction effect between childhood adversity and MDD diagnosis on subcortical brain volumes. Childhood adversity is one of the contributors to brain structural abnormalities. It is associated with subcortical brain abnormalities that are relevant to psychiatric disorders such as depression. (C) 2016 Published by Elsevier Ltd.
KW  - Depression
KW  - Childhood adversity
KW  - MRI
KW  - Caudate
KW  - Hippocampus
KW  - ENIGMA
Y1  - 2016
U6  - https://doi.org/10.1016/j.jpsychires.2016.11.010
SN  - 0022-3956
SN  - 1879-1379
VL  - 86
SP  - 58
EP  - 65
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Arnison, Paul G.
A1  - Bibb, Mervyn J.
A1  - Bierbaum, Gabriele
A1  - Bowers, Albert A.
A1  - Bugni, Tim S.
A1  - Bulaj, Grzegorz
A1  - Camarero, Julio A.
A1  - Campopiano, Dominic J.
A1  - Challis, Gregory L.
A1  - Clardy, Jon
A1  - Cotter, Paul D.
A1  - Craik, David J.
A1  - Dawson, Michael
A1  - Dittmann-Thünemann, Elke
A1  - Donadio, Stefano
A1  - Dorrestein, Pieter C.
A1  - Entian, Karl-Dieter
A1  - Fischbach, Michael A.
A1  - Garavelli, John S.
A1  - Goeransson, Ulf
A1  - Gruber, Christian W.
A1  - Haft, Daniel H.
A1  - Hemscheidt, Thomas K.
A1  - Hertweck, Christian
A1  - Hill, Colin
A1  - Horswill, Alexander R.
A1  - Jaspars, Marcel
A1  - Kelly, Wendy L.
A1  - Klinman, Judith P.
A1  - Kuipers, Oscar P.
A1  - Link, A. James
A1  - Liu, Wen
A1  - Marahiel, Mohamed A.
A1  - Mitchell, Douglas A.
A1  - Moll, Gert N.
A1  - Moore, Bradley S.
A1  - Mueller, Rolf
A1  - Nair, Satish K.
A1  - Nes, Ingolf F.
A1  - Norris, Gillian E.
A1  - Olivera, Baldomero M.
A1  - Onaka, Hiroyasu
A1  - Patchett, Mark L.
A1  - Piel, Jörn
A1  - Reaney, Martin J. T.
A1  - Rebuffat, Sylvie
A1  - Ross, R. Paul
A1  - Sahl, Hans-Georg
A1  - Schmidt, Eric W.
A1  - Selsted, Michael E.
A1  - Severinov, Konstantin
A1  - Shen, Ben
A1  - Sivonen, Kaarina
A1  - Smith, Leif
A1  - Stein, Torsten
A1  - Suessmuth, Roderich D.
A1  - Tagg, John R.
A1  - Tang, Gong-Li
A1  - Truman, Andrew W.
A1  - Vederas, John C.
A1  - Walsh, Christopher T.
A1  - Walton, Jonathan D.
A1  - Wenzel, Silke C.
A1  - Willey, Joanne M.
A1  - van der Donk, Wilfred A.
T1  - Ribosomally synthesized and post-translationally modified peptide natural products overview and recommendations for a universal nomenclature
JF  - Natural product reports : a journal of current developments in bio-organic chemistry
N2  - This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed.
Y1  - 2013
U6  - https://doi.org/10.1039/c2np20085f
SN  - 0265-0568
VL  - 30
IS  - 1
SP  - 108
EP  - 160
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Stein, S.
A1  - Friedrich, A. M.
A1  - Newman, A.
T1  - Dependence of possible characteristic earthquakes on spatial sampling: Illustration for the Wasatch seismic zone, Utah
Y1  - 2005
SN  - 0895-0695
ER  - 
TY  - BOOK
A1  - Riemenschneider, Dieter
A1  - Sarkowsky, K.
A1  - Stroh, S.
A1  - Schulze-Engler, F.
A1  - Matzke, C.
A1  - Meier, A.
A1  - Wegner, M.
A1  - Stein, Mark
A1  - Fischer, J.
A1  - Riemenschneider, K.
T1  - Postcolonial theory : the emergence of a critical discourse ; a selected and annotated bibliography
T3  - ZAA Studies : language literature culture
Y1  - 2004
SN  - 3-86057-746-8
VL  - 17
PB  - Stauffenburg-Verl.
CY  - Tübingen
ER  - 
TY  - JOUR
A1  - Essl, Franz
A1  - Dawson, Wayne
A1  - Kreft, Holger
A1  - Pergl, Jan
A1  - Pysek, Petr
A1  - van Kleunen, Mark
A1  - Weigelt, Patrick
A1  - Mang, Thomas
A1  - Dullinger, Stefan
A1  - Lenzner, Bernd
A1  - Moser, Dietmar
A1  - Maurel, Noelie
A1  - Seebens, Hanno
A1  - Stein, Anke
A1  - Weber, Ewald
A1  - Chatelain, Cyrille
A1  - Inderjit, 
A1  - Genovesi, Piero
A1  - Kartesz, John
A1  - Morozova, Olga
A1  - Nishino, Misako
A1  - Nowak, Pauline M.
A1  - Pagad, Shyama
A1  - Shu, Wen-sheng
A1  - Winter, Marten
T1  - Drivers of the relative richness of naturalized and invasive plant species on Earth
JF  - AoB PLANTS
N2  - Biological invasions are a defining feature of the Anthropocene, but the factors that determine the spatially uneven distribution of alien plant species are still poorly understood. Here, we present the first global analysis of the effects of biogeographic factors, the physical environment and socio-economy on the richness of naturalized and invasive alien plants. We used generalized linear mixed-effects models and variation partitioning to disentangle the relative importance of individual factors, and, more broadly, of biogeography, physical environment and socio-economy. As measures of the magnitude of permanent anthropogenic additions to the regional species pool and of species with negative environmental impacts, we calculated the relative richness of naturalized (= RRN) and invasive (= RRI) alien plant species numbers adjusted for the number of native species in 838 terrestrial regions. Socio-economic factors (per-capita gross domestic product (GDP), population density, proportion of agricultural land) were more important in explaining RRI (similar to 50 % of the explained variation) than RRN (similar to 40 %). Warm-temperate and (sub)tropical regions have higher RRN than tropical or cooler regions. We found that socio-economic pressures are more relevant for invasive than for naturalized species richness. The expectation that the southern hemisphere is more invaded than the northern hemisphere was confirmed only for RRN on islands, but not for mainland regions nor for RRI. On average, islands have similar to 6-fold RRN, and >3-fold RRI compared to mainland regions. Eighty-two islands (=26 % of all islands) harbour more naturalized alien than native plants. Our findings challenge the widely held expectation that socio-economic pressures are more relevant for plant naturalization than for invasive plants. To meet international biodiversity targets and halt the detrimental consequences of plant invasions, it is essential to disrupt the connection between socio-economic development and plant invasions by improving pathway management, early detection and rapid response.
KW  - Alien species richness
KW  - biogeography
KW  - invasion stages
KW  - islands
KW  - pressures
KW  - vascular plants
Y1  - 2019
U6  - https://doi.org/10.1093/aobpla/plz051
SN  - 2041-2851
VL  - 11
IS  - 5
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Lev, L.
A1  - Almogi-Labin, Ahuva
A1  - Mischke, Steffen
A1  - Ito, E.
A1  - Ben-Avraham, Zvi
A1  - Stein, M.
T1  - Paleohydrology of Lake Kinneret during the Heinrich event H2
JF  - Palaeogeography, palaeoclimatology, palaeoecology : an international journal for the geo-sciences
N2  - During the last glacial period lake Kinneret (the Sea of Galilee) fluctuated between high and low water levels reflecting the hydrological conditions of the lake watershed. Here, we focus on the hydrology of the lake after its retreat from the last glacial MIS2 (similar to 27-25 ka BP) highest stand of similar to 170 m below mean sea level (m bsl) to the low stand of similar to 214 m bsl at similar to 24-21 ka BP. The limnological-hydrological history of this time interval is recovered from trench and borehole that were dug and drilled in the southwestern shore of the lake at Ohalo-II archeological site. Cyprideis torosa (Ostracoda) recovered from the trench yielded elemental, Sr-87/Sr-86 and delta O-18 isotope data that provide information on the shore environment during the low stand period. The Sr-87/Sr-86 and Sr/Ca ratios in the ostracods, varying between similar to 0.70789 and similar to 0.70815 and 0.0017 and 0.0030, respectively indicate contributions of waters from the last glacial lake and regional runoff. The increase in the Sr-87/Sr-86 ratios reflects the decreasing effect of the last glacial Lake Kinneret waters and enhanced contribution of local runoff that washed down dried mountain soils that were previously developed during the wet and vegetated glacial. The lake retreat at similar to 24 ka BP coincided with the Heinrich event H2 at the northern Atlantic. H2 was expressed by severe aridity in Lake Kinneret-Dead Sea watershed. The limnological-hydrological change at post H2 was accompanied by 2% decrease in the delta O-18 value from -2% to -4% reflecting the change in the composition of the east Mediterranean rain sources.
 The last glacial lake Sr-87/Sr-86 ratio is similar to the Tiberias Spa saline waters and distinctly different from the modern Lake Kinneret fresh waters: Sr-87/Sr-86 similar to 0.70785 compared to similar to 0.70760, respectively. This difference is explained by enhanced contribution of Ca-chloride brines with high Sr-87/Sr-86 values to the last glacial lake and reduced Jordan River contribution due to cold freezing conditions at its headwaters, while the modern Lake Kinneret is more affected by low Sr-87/Sr-86 freshwater from the Jordan watershed.
KW  - Ostracods
KW  - Lake Kinneret
KW  - Paleolimnology
KW  - Paleohydrology
KW  - Sr-87/Sr-86
KW  - delta O-18
Y1  - 2014
U6  - https://doi.org/10.1016/j.palaeo.2014.01.005
SN  - 0031-0182
SN  - 1872-616X
VL  - 396
SP  - 183
EP  - 193
PB  - Elsevier
CY  - Amsterdam
ER  -