TY  - JOUR
A1  - Beye, Martin
A1  - Öberg, Henrik
A1  - Xin, Hongliang
A1  - Dakovski, Georgi L.
A1  - Föhlisch, Alexander
A1  - Gladh, Jorgen
A1  - Hantschmann, Markus
A1  - Hieke, Florian
A1  - Kaya, Sarp
A1  - Kühn, Danilo
A1  - LaRue, Jerry
A1  - Mercurio, Giuseppe
A1  - Minitti, Michael P.
A1  - Mitra, Ankush
A1  - Moeller, Stefan P.
A1  - Ng, May Ling
A1  - Nilsson, Anders
A1  - Nordlund, Dennis
A1  - Norskov, Jens
A1  - Öström, Henrik
A1  - Ogasawara, Hirohito
A1  - Persson, Mats
A1  - Schlotter, William F.
A1  - Sellberg, Jonas A.
A1  - Wolf, Martin
A1  - Abild-Pedersen, Frank
A1  - Pettersson, Lars G. M.
A1  - Wurth, Wilfried
T1  - Chemical Bond Activation Observed with an X-ray Laser
JF  - The journal of physical chemistry letters
N2  - The concept of bonding and antibonding orbitals is fundamental in chemistry. The population of those orbitals and the energetic difference between the two reflect the strength of the bonding interaction. Weakening the bond is expected to reduce this energetic splitting, but the transient character of bond-activation has so far prohibited direct experimental access. Here we apply time-resolved soft X-ray spectroscopy at a free electron laser to directly observe the decreased bonding antibonding splitting following bond-activation using an ultrashort optical laser pulse.
Y1  - 2016
U6  - https://doi.org/10.1021/acs.jpclett.6b01543
SN  - 1948-7185
VL  - 7
SP  - 3647
EP  - 3651
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Engeser, Stefan
A1  - Rheinberg, Falko
A1  - Moeller, Matthias
T1  - Achievement motive imagery in German schoolbooks : a pilot study testing McClelland's hypothesis
N2  - McClelland [McClelland, D.C. (1961). The achieving society. Princeton, NJ: Van Nostrand] observed that the amount of achievement imagery in children's books predicted the economic development of societies. He argued that achievement imagery is an indicator of a motivational climate, and when children grow up in a society that emphasizes the striving for achievement, they will be more economically productive later on. We tested McClelland's hypothesis by coding school textbooks for achievement imagery from two German federal states (Baden-Wurttemberg and Bremen) with pronounced differences in economic and educational conditions. As expected, the schoolbooks from the state with the more advantageous conditions contained more achievement imagery.
Y1  - 2009
UR  - http://www.sciencedirect.com/science/journal/00926566
U6  - https://doi.org/10.1016/j.jrp.2008.12.001
SN  - 0092-6566
ER  - 
TY  - JOUR
A1  - Hertrampf, Torsten
A1  - Ledwig, C.
A1  - Kulling, Sabine
A1  - Molzberger, Almut
A1  - Moeller, Frank J.
A1  - Zierau, Oliver
A1  - Vollmer, Günter
A1  - Moors, Stefan
A1  - Degen, Gisela H.
A1  - Diel, Patrick
T1  - Responses of estrogen sensitive tissues in female Wistar rats to pre- and postnatal isoflavone exposure
N2  - Effects of isoflavones on estrogen sensitive tissues are discussed controversially This study was designed to investigate tissue specific effects of an isoflavone exposure through different periods of life in female Wistar rats and to compare the effects of genistein (GEN) to those of mixed dietary isoflavones, GEN and daidzein (DAI). One group received an isoflavone-free diet (IDD). another was fed an isoflavone-rich diet (IRD) and the third group an IDD supplemented with GEN (GEN(d)) prior to mating. throughout pregnancy and up to weaning The offspring were kept on the respective diets during growth. puberty and adulthood The weight of the uterus, the height of the uterine and vaginal epithelium, the bone mineral density of the tibia, and the expression of the estrogen sensitive gene CaBP9K in the liver were determined. At d21, the uterine weight, the uterine epithelium and the expression of CaBP9K in the liver were significantly stimulated in GEN(d) animals compared to IDD and IRD Interestingly, bone mineral density was increased in GEN(d) and in IRD animals Around puberty (d50) neither uterine wet weights nor trabecular bone density differed significantly among the isoflavone groups and the IDD control. At d80 nosignificant differences in uterine weight were observed among IDD. GEN(d) and IRD animals. However, bone mineral density was increased in GEN(d) and IRD animals In summary, Our results demonstrate that lifelong dietary exposure to isoflavones can affect estrogen sensitive tissues, apparently in a tissue selective manner With respect to health risk and benefit our data indicate that an increased bone mineral density can be achieved by lifelong exposure to an IRD. which, in contrast to GEN supplementation, does not seem to stimulate the proliferation of the uterine epithelium
Y1  - 2009
UR  - http://www.sciencedirect.com/science/journal/03784274
U6  - https://doi.org/10.1016/j.toxlet.2009.08.019
SN  - 0378-4274
ER  - 
TY  - JOUR
A1  - Schildknecht, Stefan
A1  - Pape, Regina
A1  - Meiser, Johannes
A1  - Karreman, Christiaan
A1  - Strittmatter, Tobias
A1  - Odermatt, Meike
A1  - Cirri, Erica
A1  - Friemel, Anke
A1  - Ringwald, Markus
A1  - Pasquarelli, Noemi
A1  - Ferger, Boris
A1  - Brunner, Thomas
A1  - Marx, Andreas
A1  - Moeller, Heiko M.
A1  - Hiller, Karsten
A1  - Leist, Marcel
T1  - Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP+ by Transporter-Independent Export of the Intermediate MPDP+
JF  - Antioxidants & redox signaling
N2  - Aims: 1-Methyl-4-phenyl-tetrahydropyridine (MPTP) is among the most widely used neurotoxins for inducing experimental parkinsonism. MPTP causes parkinsonian symptoms in mice, primates, and humans by killing a subpopulation of dopaminergic neurons. Extrapolations of data obtained using MPTP-based parkinsonism models to human disease are common; however, the precise mechanism by which MPTP is converted into its active neurotoxic metabolite, 1-methyl-4-phenyl-pyridinium (MPP+), has not been fully elucidated. In this study, we aimed to address two unanswered questions related to MPTP toxicology: (1) Why are MPTP-converting astrocytes largely spared from toxicity? (2) How does MPP+ reach the extracellular space? Results: In MPTP-treated astrocytes, we discovered that the membrane-impermeable MPP+, which is generally assumed to be formed inside astrocytes, is almost exclusively detected outside of these cells. Instead of a transporter-mediated export, we found that the intermediate, 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+), and/or its uncharged conjugate base passively diffused across cell membranes and that MPP+ was formed predominately by the extracellular oxidation of MPDP+ into MPP+. This nonenzymatic extracellular conversion of MPDP+ was promoted by O-2, a more alkaline pH, and dopamine autoxidation products. Innovation and Conclusion: Our data indicate that MPTP metabolism is compartmentalized between intracellular and extracellular environments, explain the absence of toxicity in MPTP-converting astrocytes, and provide a rationale for the preferential formation of MPP+ in the extracellular space. The mechanism of transporter-independent extracellular MPP+ formation described here indicates that extracellular genesis of MPP+ from MPDP is a necessary prerequisite for the selective uptake of this toxin by catecholaminergic neurons.
Y1  - 2015
U6  - https://doi.org/10.1089/ars.2015.6297
SN  - 1523-0864
SN  - 1557-7716
VL  - 23
IS  - 13
SP  - 1001
EP  - 1016
PB  - Liebert
CY  - New Rochelle
ER  - 
TY  - JOUR
A1  - Kubin, Markus
A1  - Kern, Jan
A1  - Gul, Sheraz
A1  - Kroll, Thomas
A1  - Chatterjee, Ruchira
A1  - Loechel, Heike
A1  - Fuller, Franklin D.
A1  - Sierra, Raymond G.
A1  - Quevedo, Wilson
A1  - Weniger, Christian
A1  - Rehanek, Jens
A1  - Firsov, Anatoly
A1  - Laksmono, Hartawan
A1  - Weninger, Clemens
A1  - Alonso-Mori, Roberto
A1  - Nordlund, Dennis L.
A1  - Lassalle-Kaiser, Benedikt
A1  - Glownia, James M.
A1  - Krzywinski, Jacek
A1  - Moeller, Stefan
A1  - Turner, Joshua J.
A1  - Minitti, Michael P.
A1  - Dakovski, Georgi L.
A1  - Koroidov, Sergey
A1  - Kawde, Anurag
A1  - Kanady, Jacob S.
A1  - Tsui, Emily Y.
A1  - Suseno, Sandy
A1  - Han, Zhiji
A1  - Hill, Ethan
A1  - Taguchi, Taketo
A1  - Borovik, Andrew S.
A1  - Agapie, Theodor
A1  - Messinger, Johannes
A1  - Erko, Alexei
A1  - Föhlisch, Alexander
A1  - Bergmann, Uwe
A1  - Mitzner, Rolf
A1  - Yachandra, Vittal K.
A1  - Yano, Junko
A1  - Wernet, Philippe
T1  - Soft x-ray absorption spectroscopy of metalloproteins and high-valent metal-complexes at room temperature using free-electron lasers
JF  - Structural dynamics
N2  - X-ray absorption spectroscopy at the L-edge of 3d transition metals provides unique information on the local metal charge and spin states by directly probing 3d-derived molecular orbitals through 2p-3d transitions. However, this soft x-ray technique has been rarely used at synchrotron facilities for mechanistic studies of metalloenzymes due to the difficulties of x-ray-induced sample damage and strong background signals from light elements that can dominate the low metal signal. Here, we combine femtosecond soft x-ray pulses from a free-electron laser with a novel x-ray fluorescence-yield spectrometer to overcome these difficulties. We present L-edge absorption spectra of inorganic high-valent Mn complexes (Mn similar to 6-15 mmol/l) with no visible effects of radiation damage. We also present the first L-edge absorption spectra of the oxygen evolving complex (Mn4CaO5) in Photosystem II (Mn < 1 mmol/l) at room temperature, measured under similar conditions. Our approach opens new ways to study metalloenzymes under functional conditions. (C) 2017 Author(s).
Y1  - 2017
U6  - https://doi.org/10.1063/1.4986627
SN  - 2329-7778
VL  - 4
PB  - American Institute of Physics
CY  - Melville
ER  - 
TY  - JOUR
A1  - Kroll, Thomas
A1  - Kern, Jan
A1  - Kubin, Markus
A1  - Ratner, Daniel
A1  - Gul, Sheraz
A1  - Fuller, Franklin D.
A1  - Löchel, Heike
A1  - Krzywinski, Jacek
A1  - Lutman, Alberto
A1  - Ding, Yuantao
A1  - Dakovski, Georgi L.
A1  - Moeller, Stefan
A1  - Turner, Joshua J.
A1  - Alonso-Mori, Roberto
A1  - Nordlund, Dennis L.
A1  - Rehanek, Jens
A1  - Weniger, Christian
A1  - Firsov, Alexander
A1  - Brzhezinskaya, Maria
A1  - Chatterjee, Ruchira
A1  - Lassalle-Kaiser, Benedikt
A1  - Sierra, Raymond G.
A1  - Laksmono, Hartawan
A1  - Hill, Ethan
A1  - Borovik, Andrew S.
A1  - Erko, Alexei
A1  - Föhlisch, Alexander
A1  - Mitzner, Rolf
A1  - Yachandra, Vittal K.
A1  - Yano, Junko
A1  - Wernet, Philippe
A1  - Bergmann, Uwe
T1  - X-ray absorption spectroscopy using a self-seeded soft X-ray free-electron laser
JF  - Optics express : the international electronic journal of optics
N2  - X-ray free electron lasers (XFELs) enable unprecedented new ways to study the electronic structure and dynamics of transition metal systems. L-edge absorption spectroscopy is a powerful technique for such studies and the feasibility of this method at XFELs for solutions and solids has been demonstrated. However, the required x-ray bandwidth is an order of magnitude narrower than that of self-amplified spontaneous emission (SASE), and additional monochromatization is needed. Here we compare L-edge x-ray absorption spectroscopy (XAS) of a prototypical transition metal system based on monochromatizing the SASE radiation of the linac coherent light source (LCLS) with a new technique based on self-seeding of LCLS. We demonstrate how L-edge XAS can be performed using the self-seeding scheme without the need of an additional beam line monochromator. We show how the spectral shape and pulse energy depend on the undulator setup and how this affects the x-ray spectroscopy measurements. (C) 2016 Optical Society of America
Y1  - 2016
U6  - https://doi.org/10.1364/OE.24.022469
SN  - 1094-4087
VL  - 24
SP  - 22469
EP  - 22480
PB  - Optical Society of America
CY  - Washington
ER  - 
TY  - JOUR
A1  - Eckert, Sebastian
A1  - Norell, Jesper
A1  - Miedema, Piter S.
A1  - Beye, Martin
A1  - Fondell, Mattis
A1  - Quevedo, Wilson
A1  - Kennedy, Brian
A1  - Hantschmann, Markus
A1  - Pietzsch, Annette
A1  - van Kuiken, Benjamin
A1  - Ross, Matthew
A1  - Minitti, Michael P.
A1  - Moeller, Stefan P.
A1  - Schlotter, William F.
A1  - Khalil, Munira
A1  - Odelius, Michael
A1  - Föhlisch, Alexander
T1  - Untersuchung unabhängiger N‐H‐ und N‐C‐Bindungsverformungen auf ultrakurzen Zeitskalen mit resonanter inelastischer Röntgenstreuung
JF  - Angewandte Chemie
N2  - Die Femtosekundendynamik nach resonanten Photoanregungen mit optischen und Röntgenpulsen ermöglicht eine selektive Verformung von chemischen N‐H‐ und N‐C‐Bindungen in 2‐Thiopyridon in wässriger Lösung. Die Untersuchung der orbitalspezifischen elektronischen Struktur und ihrer Dynamik auf ultrakurzen Zeitskalen mit resonanter inelastischer Röntgenstreuung an der N1s‐Resonanz am Synchrotron und dem Freie‐Elektronen‐Laser LCLS in Kombination mit quantenchemischen Multikonfigurationsberechnungen erbringen den direkten Nachweis dieser kontrollierten photoinduzierten Molekülverformungen und ihrer ultrakurzen Zeitskala.
KW  - Photochemie
KW  - Protonierung
KW  - RIXS (resonante inelastische Röntgenstreuung)
KW  - Selektiver Bindungsbruch
KW  - Stickstoff
Y1  - 2017
U6  - https://doi.org/10.1002/ange.201700239
SN  - 1521-3757
SN  - 1521-3773
VL  - 129
IS  - 22
SP  - 6184
EP  - 6188
ER  - 
TY  - JOUR
A1  - Eckert, Sebastian
A1  - Norell, Jesper
A1  - Miedema, Piter S.
A1  - Beye, Martin
A1  - Fondell, Mattis
A1  - Quevedo, Wilson
A1  - Kennedy, Brian
A1  - Hantschmann, Markus
A1  - Pietzsch, Annette
A1  - Van Kuiken, Benjamin E.
A1  - Ross, Matthew
A1  - Minitti, Michael P.
A1  - Moeller, Stefan P.
A1  - Schlotter, William F.
A1  - Khalil, Munira
A1  - Odelius, Michael
A1  - Föhlisch, Alexander
T1  - Ultrafast Independent N-H and N-C Bond Deformation Investigated with Resonant Inelastic X-Ray Scattering
JF  - Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker ; International edition
N2  - The femtosecond excited-state dynamics following resonant photoexcitation enable the selective deformation of N-H and N-C chemical bonds in 2-thiopyridone in aqueous solution with optical or X-ray pulses. In combination with multiconfigurational quantum-chemical calculations, the orbital-specific electronic structure and its ultrafast dynamics accessed with resonant inelastic X-ray scattering at the N 1s level using synchrotron radiation and the soft X-ray free-electron laser LCLS provide direct evidence for this controlled photoinduced molecular deformation and its ultrashort time-scale.
KW  - nitrogen
KW  - photochemistry
KW  - protonation
KW  - RIXS (resonant inelastic X-ray scattering)
KW  - selective bond cleavage
Y1  - 2017
U6  - https://doi.org/10.1002/anie.201700239
SN  - 1433-7851
SN  - 1521-3773
VL  - 56
SP  - 6088
EP  - 6092
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Jay, Raphael M.
A1  - Norell, Jesper
A1  - Eckert, Sebastian
A1  - Hantschmann, Markus
A1  - Beye, Martin
A1  - Kennedy, Brian
A1  - Quevedo, Wilson
A1  - Schlotter, William F.
A1  - Dakovski, Georgi L.
A1  - Minitti, Michael P.
A1  - Hoffmann, Matthias C.
A1  - Mitra, Ankush
A1  - Moeller, Stefan P.
A1  - Nordlund, Dennis
A1  - Zhang, Wenkai
A1  - Liang, Huiyang W.
A1  - Kunnus, Kristian
A1  - Kubicek, Katharina
A1  - Techert, Simone A.
A1  - Lundberg, Marcus
A1  - Wernet, Philippe
A1  - Gaffney, Kelly
A1  - Odelius, Michael
A1  - Föhlisch, Alexander
T1  - Disentangling Transient Charge Density and Metal-Ligand Covalency in Photoexcited Ferricyanide with Femtosecond Resonant Inelastic Soft X-ray Scattering
JF  - The journal of physical chemistry letters
N2  - Soft X-ray spectroscopies are ideal probes of the local valence electronic structure of photocatalytically active metal sites. Here, we apply the selectivity of time resolved resonant inelastic X-ray scattering at the iron L-edge to the transient charge distribution of an optically excited charge-transfer state in aqueous ferricyanide. Through comparison to steady-state spectra and quantum chemical calculations, the coupled effects of valence-shell closing and ligand-hole creation are experimentally and theoretically disentangled and described in terms of orbital occupancy, metal-ligand covalency, and ligand field splitting, thereby extending established steady-state concepts to the excited-state domain. pi-Back-donation is found to be mainly determined by the metal site occupation, whereas the ligand hole instead influences sigma-donation. Our results demonstrate how ultrafast resonant inelastic X-ray scattering can help characterize local charge distributions around catalytic metal centers in short-lived charge-transfer excited states, as a step toward future rationalization and tailoring of photocatalytic capabilities of transition-metal complexes.
Y1  - 2018
U6  - https://doi.org/10.1021/acs.jpclett.8b01429
SN  - 1948-7185
VL  - 9
IS  - 12
SP  - 3538
EP  - 3543
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Eckert, Sebastian
A1  - Beye, Martin
A1  - Pietzsch, Annette
A1  - Quevedo, Wilson
A1  - Hantschmann, Markus
A1  - Ochmann, Miguel
A1  - Ross, Matthew
A1  - Minitti, Michael P.
A1  - Turner, Joshua J.
A1  - Moeller, Stefan P.
A1  - Schlotter, William F.
A1  - Dakovski, Georgi L.
A1  - Khalil, Munira
A1  - Huse, Nils
A1  - Föhlisch, Alexander
T1  - Principles of femtosecond X-ray/optical cross-correlation with X-ray induced transient optical reflectivity in solids
JF  - Applied physics letters
N2  - The discovery of ultrafast X-ray induced optical reflectivity changes enabled the development of X-ray/optical cross correlation techniques at X-ray free electron lasers worldwide. We have now linked through experiment and theory the fundamental excitation and relaxation steps with the transient optical properties in finite solid samples. Therefore, we gain a thorough interpretation and an optimized detection scheme of X-ray induced changes to the refractive index and the X-ray/optical cross correlation response. (C) 2015 AIP Publishing LLC.
Y1  - 2015
U6  - https://doi.org/10.1063/1.4907949
SN  - 0003-6951
SN  - 1077-3118
VL  - 106
IS  - 6
PB  - American Institute of Physics
CY  - Melville
ER  - 
TY  - JOUR
A1  - Schreck, Simon
A1  - Beye, Martin
A1  - Sellberg, Jonas A.
A1  - McQueen, Trevor
A1  - Laksmono, Hartawan
A1  - Kennedy, Brian
A1  - Eckert, Sebastian
A1  - Schlesinger, Daniel
A1  - Nordlund, Dennis
A1  - Ogasawara, Hirohito
A1  - Sierra, Raymond G.
A1  - Segtnan, Vegard H.
A1  - Kubicek, Katharina
A1  - Schlotter, William F.
A1  - Dakovski, Georgi L.
A1  - Moeller, Stefan P.
A1  - Bergmann, Uwe
A1  - Techert, Simone
A1  - Pettersson, Lars G. M.
A1  - Wernet, Philippe
A1  - Bogan, Michael J.
A1  - Harada, Yoshihisa
A1  - Nilsson, Anders
A1  - Föhlisch, Alexander
T1  - Reabsorption of soft x-ray emission at high x-ray free-electron laserfluences
JF  - Physical review letters
N2  - We report on oxygen K-edge soft x-ray emission spectroscopy from a liquid water jet at the Linac Coherent Light Source. We observe significant changes in the spectral content when tuning over a wide range of incident x-ray fluences. In addition the total emission yield decreases at high fluences. These modifications result from reabsorption of x-ray emission by valence-excited molecules generated by the Auger cascade. Our observations have major implications for future x-ray emission studies at intense x-ray sources. We highlight the importance of the x-ray pulse length with respect to the core-hole lifetime.
Y1  - 2014
U6  - https://doi.org/10.1103/PhysRevLett.113.153002
SN  - 0031-9007
SN  - 1079-7114
VL  - 113
IS  - 15
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - GEN
A1  - Eckert, Sebastian
A1  - Norell, Jesper
A1  - Miedema, Piter S.
A1  - Beye, Martin
A1  - Fondell, Mattis
A1  - Quevedo, Wilson
A1  - Kennedy, Brian
A1  - Hantschmann, Markus
A1  - Pietzsch, Annette
A1  - van Kuiken, Benjamin E.
A1  - Ross, Matthew
A1  - Minitti, Michael P.
A1  - Moeller, Stefan P.
A1  - Schlotter, William F.
A1  - Khalil, Munira
A1  - Odelius, Michael
A1  - Föhlisch, Alexander
T1  - Untersuchung unabhängiger N‐H‐ und N‐C‐Bindungsverformungen auf ultrakurzen Zeitskalen mit resonanter inelastischer Röntgenstreuung
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Die Femtosekundendynamik nach resonanten Photoanregungen mit optischen und Röntgenpulsen ermöglicht eine selektive Verformung von chemischen N‐H‐ und N‐C‐Bindungen in 2‐Thiopyridon in wässriger Lösung. Die Untersuchung der orbitalspezifischen elektronischen Struktur und ihrer Dynamik auf ultrakurzen Zeitskalen mit resonanter inelastischer Röntgenstreuung an der N1s‐Resonanz am Synchrotron und dem Freie‐Elektronen‐Laser LCLS in Kombination mit quantenchemischen Multikonfigurationsberechnungen erbringen den direkten Nachweis dieser kontrollierten photoinduzierten Molekülverformungen und ihrer ultrakurzen Zeitskala.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1121 
KW  - Photochemie
KW  - Protonierung
KW  - RIXS (resonante inelastische Röntgenstreuung)
KW  - Selektiver Bindungsbruch
KW  - Stickstoff
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-436688
SN  - 1866-8372
IS  - 1121
ER  - 
TY  - GEN
A1  - Eckert, Sebastian
A1  - Norell, Jesper
A1  - Miedema, Piter S.
A1  - Beye, Martin
A1  - Fondell, Mattis
A1  - Quevedo, Wilson
A1  - Kennedy, Brian
A1  - Hantschmann, Markus
A1  - Pietzsch, Annette
A1  - van Kuiken, Benjamin E.
A1  - Ross, Matthew
A1  - Minitti, Michael P.
A1  - Moeller, Stefan P.
A1  - Schlotter, William F.
A1  - Khalil, Munira
A1  - Odelius, Michael
A1  - Föhlisch, Alexander
T1  - Ultrafast Independent N-H and N-C Bond Deformation Investigated with Resonant Inelastic X-Ray Scattering
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - The femtosecond excited-state dynamics following resonant photoexcitation enable the selective deformation of N-H and N-C chemical bonds in 2-thiopyridone in aqueous solution with optical or X-ray pulses. In combination with multiconfigurational quantum-chemical calculations, the orbital-specific electronic structure and its ultrafast dynamics accessed with resonant inelastic X-ray scattering at the N 1s level using synchrotron radiation and the soft X-ray free-electron laser LCLS provide direct evidence for this controlled photoinduced molecular deformation and its ultrashort time-scale.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1115 
KW  - nitrogen
KW  - photochemistry
KW  - protonation
KW  - RIXS (resonant inelastic X-ray scattering)
KW  - selective bond cleavage
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-436873
SN  - 1866-8372
IS  - 1115
ER  - 
TY  - GEN
A1  - de Vera, Jean-Pierre Paul
A1  - Alawi, Mashal
A1  - Backhaus, Theresa
A1  - Baque, Mickael
A1  - Billi, Daniela
A1  - Boettger, Ute
A1  - Berger, Thomas
A1  - Bohmeier, Maria
A1  - Cockell, Charles
A1  - Demets, Rene
A1  - de la Torre Noetzel, Rosa
A1  - Edwards, Howell
A1  - Elsaesser, Andreas
A1  - Fagliarone, Claudia
A1  - Fiedler, Annelie
A1  - Foing, Bernard
A1  - Foucher, Frederic
A1  - Fritz, Jörg
A1  - Hanke, Franziska
A1  - Herzog, Thomas
A1  - Horneck, Gerda
A1  - Hübers, Heinz-Wilhelm
A1  - Huwe, Björn
A1  - Joshi, Jasmin Radha
A1  - Kozyrovska, Natalia
A1  - Kruchten, Martha
A1  - Lasch, Peter
A1  - Lee, Natuschka
A1  - Leuko, Stefan
A1  - Leya, Thomas
A1  - Lorek, Andreas
A1  - Martinez-Frias, Jesus
A1  - Meessen, Joachim
A1  - Moritz, Sophie
A1  - Moeller, Ralf
A1  - Olsson-Francis, Karen
A1  - Onofri, Silvano
A1  - Ott, Sieglinde
A1  - Pacelli, Claudia
A1  - Podolich, Olga
A1  - Rabbow, Elke
A1  - Reitz, Günther
A1  - Rettberg, Petra
A1  - Reva, Oleg
A1  - Rothschild, Lynn
A1  - Garcia Sancho, Leo
A1  - Schulze-Makuch, Dirk
A1  - Selbmann, Laura
A1  - Serrano, Paloma
A1  - Szewzyk, Ulrich
A1  - Verseux, Cyprien
A1  - Wadsworth, Jennifer
A1  - Wagner, Dirk
A1  - Westall, Frances
A1  - Wolter, David
A1  - Zucconi, Laura
T1  - Limits of life and the habitability of Mars
BT  - the ESA space experiment BIOMEX on the ISS
T2  - Astrobiology
N2  - BIOMEX (BIOlogy and Mars EXperiment) is an ESA/Roscosmos space exposure experiment housed within the exposure facility EXPOSE-R2 outside the Zvezda module on the International Space Station (ISS). The design of the multiuser facility supports-among others-the BIOMEX investigations into the stability and level of degradation of space-exposed biosignatures such as pigments, secondary metabolites, and cell surfaces in contact with a terrestrial and Mars analog mineral environment. In parallel, analysis on the viability of the investigated organisms has provided relevant data for evaluation of the habitability of Mars, for the limits of life, and for the likelihood of an interplanetary transfer of life (theory of lithopanspermia). In this project, lichens, archaea, bacteria, cyanobacteria, snow/permafrost algae, meristematic black fungi, and bryophytes from alpine and polar habitats were embedded, grown, and cultured on a mixture of martian and lunar regolith analogs or other terrestrial minerals. The organisms and regolith analogs and terrestrial mineral mixtures were then exposed to space and to simulated Mars-like conditions by way of the EXPOSE-R2 facility. In this special issue, we present the first set of data obtained in reference to our investigation into the habitability of Mars and limits of life. This project was initiated and implemented by the BIOMEX group, an international and interdisciplinary consortium of 30 institutes in 12 countries on 3 continents. Preflight tests for sample selection, results from ground-based simulation experiments, and the space experiments themselves are presented and include a complete overview of the scientific processes required for this space experiment and postflight analysis. The presented BIOMEX concept could be scaled up to future exposure experiments on the Moon and will serve as a pretest in low Earth orbit.
KW  - EXPOSE-R2
KW  - BIOMEX
KW  - Habitability
KW  - Limits of life
KW  - Extremophiles
KW  - Mars
Y1  - 2019
U6  - https://doi.org/10.1089/ast.2018.1897
SN  - 1531-1074
SN  - 1557-8070
VL  - 19
IS  - 2
SP  - 145
EP  - 157
PB  - Liebert
CY  - New Rochelle
ER  -