TY - JOUR A1 - Chromik, Jonas A1 - Klopfenstein, Sophie Anne Ines A1 - Pfitzner, Bjarne A1 - Sinno, Zeena-Carola A1 - Arnrich, Bert A1 - Balzer, Felix A1 - Poncette, Akira-Sebastian T1 - Computational approaches to alleviate alarm fatigue in intensive care medicine: a systematic literature review JF - Frontiers in digital health N2 - Patient monitoring technology has been used to guide therapy and alert staff when a vital sign leaves a predefined range in the intensive care unit (ICU) for decades. However, large amounts of technically false or clinically irrelevant alarms provoke alarm fatigue in staff leading to desensitisation towards critical alarms. With this systematic review, we are following the Preferred Reporting Items for Systematic Reviews (PRISMA) checklist in order to summarise scientific efforts that aimed to develop IT systems to reduce alarm fatigue in ICUs. 69 peer-reviewed publications were included. The majority of publications targeted the avoidance of technically false alarms, while the remainder focused on prediction of patient deterioration or alarm presentation. The investigated alarm types were mostly associated with heart rate or arrhythmia, followed by arterial blood pressure, oxygen saturation, and respiratory rate. Most publications focused on the development of software solutions, some on wearables, smartphones, or headmounted displays for delivering alarms to staff. The most commonly used statistical models were tree-based. In conclusion, we found strong evidence that alarm fatigue can be alleviated by IT-based solutions. However, future efforts should focus more on the avoidance of clinically non-actionable alarms which could be accelerated by improving the data availability. KW - alarm fatigue KW - alarm management KW - alarm optimisation KW - intensive care unit KW - IT system KW - patient monitoring KW - ICU KW - critical care Y1 - 2022 U6 - https://doi.org/10.3389/fdgth.2022.843747 SN - 2673-253X VL - 4 PB - Frontiers Media CY - Lausanne ER -