TY  - JOUR
A1  - Sicilia, T.
A1  - Bub, Achim
A1  - Rechkemmer, G.
A1  - Kraemer, K.
A1  - Hoppe, P. P.
A1  - Kulling, Sabine E.
T1  - Novel lycopene metabolites are detectable in plasma of preruminant calves after lycopene supplementation
N2  - Appropriate animal models such as preruminant calves are necessary to study the complex physiological functions of carotenoids and to relate them to possible health effects in humans. In this study, the bioavailability and metabolism of lycopene from 2 dietary supplements were compared. LycoVit (R) containing synthetic lycopene and Lyc-O- Mato (R) containing natural tomato oleoresin were administered to 2 groups of preruminant calves (each n = 8) for 14 d in daily doses of 15 mg of lycopene. Plasma was analyzed for carotenoids before the intervention period, directly after, and each day for 5 d after the end of the intervention. All-trans and 5-cis lycopene, and 3 lycopene metabolites not previously found in calf plasma were detected. These metabolites contributed 52% of the total lycopene content measured at the end of the intervention period. Based on spectroscopic data, they might be hydrogenation products, which are formed from all-trans and/or 5-cis lycopene. In the LycoVit group, total lycopene concentrations were similar to 300% higher (286 +/- 89 nmol/L) than in the Lyc-O-Mato group (72 33 nmol/L) (P < 0.001). This indicates that, unlike in humans, lycopene from LycoVit and Lyc-O-Mato does not have equal bioavailabilities in preruminant calves. Therefore, the preruminant calf may not be a suitable animal model with which to study the biological and physiological effects of lycopene
Y1  - 2005
SN  - 0022-3166
ER  - 
TY  - JOUR
A1  - Garofalo, F.
A1  - Foti, S.
A1  - Hollender, F.
A1  - Bard, Pierre-Yves
A1  - Cornou, C.
A1  - Cox, B. R.
A1  - Ohrnberger, Matthias
A1  - Sicilia, D.
A1  - Asten, M.
A1  - Di Giulio, G.
A1  - Forbriger, T.
A1  - Guillier, B.
A1  - Hayashi, K.
A1  - Martin, A.
A1  - Matsushima, Satoru
A1  - Mercerat, D.
A1  - Poggi, V.
A1  - Yamanaka, H.
T1  - InterPACIFIC project: Comparison of invasive and non-invasive methods for seismic site characterization. Part I: Intra-comparison of surface wave methods
JF  - Soil Dynamics and Earthquake Engineering
N2  - The main scope of the InterPACIFIC (Intercomparison of methods for site parameter and velocity profile characterization) project is to assess the reliability of in-hole and surface-wave methods, used for estimating shear wave velocity. Three test-sites with different subsurface conditions were chosen: a soft soil, a stiff soil and a rock outcrop. This paper reports the surface-wave methods results. Specifically 14 teams of expert users analysed the same experimental surface-wave datasets, consisting of both passive and active data. Each team adopted their own strategy to retrieve the dispersion curve and the shear-wave velocity profile at each site. Despite different approaches, the dispersion curves are quite in agreement with each other. Conversely, the shear-wave velocity profiles show a certain variability that increases in correspondence of major stratigraphic interfaces. This larger variability is mainly due to non-uniqueness of the solution and lateral variability. As expected, the observed variability in V-s,V-30 estimatesis small, as solution non-uniqueness plays a limited role. (C) 2015 Elsevier Ltd. All rights reserved.
KW  - Surface-wave methods
KW  - Dispersion curve
KW  - Inversion
KW  - V-s,V-30
KW  - Site characterization
KW  - MASW
KW  - Microtremors
KW  - Rayleigh waves
KW  - Geophysical methods
Y1  - 2016
U6  - https://doi.org/10.1016/j.soildyn.2015.12.010
SN  - 0267-7261
SN  - 1879-341X
VL  - 82
SP  - 222
EP  - 240
PB  - Elsevier
CY  - Oxford
ER  -