TY - CHAP A1 - Borowski, Andreas A1 - Glowinski, Ingrid A1 - Frister, Jonas A1 - Höttecke, Dietmar A1 - Buth, Katrin A1 - Koenen, Jenna A1 - Masanek, Nicole A1 - Reichwein, Wilko A1 - Scholten, Nina A1 - Sprenger, Sandra A1 - Stender, Peter A1 - Wöhlke, Carina A1 - Komorek, Michael A1 - Freckmann, Janine A1 - Hofmann, Josefine A1 - Niesel, Verena A1 - Richter, Chris A1 - Mehlmann, Nelli A1 - Bikner-Ahsbahs, Angelika A1 - Unverricht, Katja A1 - Schanze, Sascha A1 - Bittorf, Robert Marten A1 - Meier, Monique A1 - Grospietsch, Finja A1 - Mayer, Jürgen A1 - Gimbel, Katharina A1 - Ziepprecht, Kathrin A1 - Hofmann, Judith A1 - Kramer, Charlotte A1 - Müller, Britta-Kornelia A1 - Rohde, Andreas A1 - Zühlsdorf, Felix A1 - Winkler, Iris A1 - Laging, Ralf A1 - Peter, Carina A1 - Schween, Michael A1 - Härle, Gerhard A1 - Busse, Beatrix A1 - Mahner, Sebastian A1 - Köstler, Verena A1 - Kufner, Sabrina A1 - Mägdefrau, Jutta A1 - Müller, Christian A1 - Beck, Christina A1 - Kriehuber, Eva A1 - Boch, Florian A1 - Engl, Anna-Teresa A1 - Helzel, Andreas A1 - Pickert, Tina A1 - Reiter, Christian A1 - Blasini, Bettina A1 - Nerdel, Claudia A1 - Lewalter, Doris A1 - Schiffhauer, Silke A1 - Richter-Gebert, Jürgen A1 - Bannert, Maria A1 - Maahs, Mirjam A1 - Reißner, Maria A1 - Ungar, Patrizia A1 - von Wachter, Jana-Kristin A1 - Hellmann, Katharina A1 - Zaki, Katja A1 - Pohlenz, Philipp ED - Glowinski, Ingrid ED - Borowski, Andreas ED - Gillen, Julia ED - Schanze, Sascha ED - von Meien, Joachim T1 - Kohärenz in der universitären Lehrerbildung T1 - Coherence in teacher education at university BT - Vernetzung von Fachwissenschaft, Fachdidaktik und Bildungswissenschaften BT - linking studies in content knowledge, pedagogical content knowledge and pedagogical knowledge in teacher education N2 - One area that is supported by the project “Qualitätsoffensive Lehrerbildung” (funded by BMBF) is the improvement of collaboration and coordination between studies in the discipline, studies in pedagogical content knowledge, and studies in pedagogical knowledge during teacher education at university. Aiming a better coordination among these three parts of teacher education at university, many of the supported projects have designed and realized university-specific approaches. This conference proceedings volume comprises contributions by 15 of these projects. Seven of those were introduced and discussed in workshops on the occasion of two cross-regional project-conferences in Hannover and Potsdam. Overall, the contributions give a theoretically funded as well as a practice-oriented overview of current approaches and concepts to achieve a better connection between study units concerning studies in content knowledge, pedagogical content knowledge and pedagogical knowledge in teacher education. The volume presents university projects, which take effect on different levels (at the level of curriculum and content, at a collegiate level, at the level of structural conditions of universities). The different approaches are described in a way that they can provide a basis for transfer to other subjects or further universities. The contributions are aimed at teacher educators as well as other actors working in the field of teaching- and quality development at universities. All of them can take transferable ideas and impulses from the described concepts and formats. N2 - Eine verbesserte Zusammenarbeit und Abstimmung von Fachwissenschaft, Fachdidaktik, Bildungswissenschaften und schulpraktischen Lernorten ist einer der Förderbereiche der „Qualitätsoffensive Lehrerbildung“. Zahlreiche der geförderten Projekte haben für dieses Handlungsfeld im Bereich Vernetzung von Fachwissenschaft, Fachdidaktik und Bildungswissenschaften hochschulspezifische Maßnahmen konzipiert und umgesetzt. Der vorliegende Tagungsband beinhaltet Beiträge von 15 entsprechenden Projekten, von denen sieben anlässlich von zwei standortübergreifenden Projekt-Tagungen in Hannover und Potsdam vorgestellt und in Workshops diskutiert wurden. Insgesamt geben die Beiträge einen theoretisch fundierten und gleichzeitig praxisorientierten Überblick über aktuelle Ansätze und Konzepte zur besseren Vernetzung fachwissenschaftlicher, fachdidaktischer und bildungswissenschaftlicher Studienanteile im Lehramtsstudium. Dargestellt werden Projektarbeiten der Hochschulen, die auf verschiedenen Ebenen wirksam werden (curricular-inhaltliche Ebene, kollegiale Ebene, hochschul-strukturelle Ebene). Die Maßnahmen sind so beschrieben, dass sie als Grundlage für einen Transfer auf andere Fächer bzw. andere Standorte genutzt werden können. Die Beiträge richten sich an alle Lehrenden im Bereich der Lehramtsbildung sowie sonstige Akteure im Bereich der Lehr- und Qualitätsentwicklung an den Universitäten. Sie alle können den beschriebenen Konzepten und Umsetzungsformaten transferierbare Ideen und Impulse entnehmen. KW - Professionswissen KW - universitäre Lehrerbildung KW - Vernetzung Fachwissenschaft KW - Fachdidaktik KW - Bildungswissenschaft KW - Lehramtsstudium KW - teacher education KW - professional knowledge KW - content knowledge KW - pedagogical content knowledge Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-414267 SN - 978-3-86956-438-8 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Krah, Markus A1 - Thulin, Mirjam A1 - Faierstein, Morris M. A1 - Drori, Danielle A1 - Coors, Maria A1 - Schramm, Netta A1 - Driver, Cory A1 - Holzman, Gitit A1 - Zuckermann, Ghil‘ad A1 - Fishbane, Eitan P. A1 - Gruenbaum, Caroline A1 - Schirrmeister, Sebastian A1 - Ferrari, Francesco A1 - Stemberger, Günter A1 - Schmölz-Häberlein, Michaela A1 - Müller, Judith A1 - Schulz, Michael Karl A1 - Meyer, Thomas A1 - Artwińska, Anna A1 - Walter, Simon ED - Krah, Markus ED - Thulin, Mirjam ED - Pick, Bianca T1 - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien = Transformative Translations in Jewish History and Culture BT - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e. V. N2 - PaRDeS, die Zeitschrift der Vereinigung für Jüdische Studien e. V., erforscht die fruchtbare kulturelle Vielfalt des Judentums sowie ihre Berührungspunkte zur nichtjüdischen Umwelt in unterschiedlichen Bereichen. Daneben dient die Zeitschrift als Forum zur Positionierung der Fächer Jüdische Studien und ­Judaistik innerhalb des wissenschaftlichen Diskurses sowie zur Diskussion ihrer historischen und gesellschaftlichen Verantwortung. N2 - PaRDeS, the journal of the German Association for Jewish Studies, aims at exploring the fruitful and multifarious cultures of Judaism as well as their relations to their environment within diverse areas of research. In addition, the journal promotes Jewish Studies within academic discourse and reflects on its historic and social responsibilities. T3 - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. - 25 KW - Jüdische Studien KW - Übersetzungen KW - Bibel KW - Hebräisch KW - Jiddisch KW - Jewish Studies KW - Translations KW - Bible KW - Hebrew KW - Yiddish Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-432621 SN - 978-3-86956-468-5 SN - 1614-6492 SN - 1862-7684 IS - 25 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Askin, Elif A1 - Emmerich-Fritsche, Angelika A1 - Goppel, Anna A1 - Hemmerling, Mario A1 - Kapaun, Nina A1 - Lohmann, Georg A1 - Müller, Sebastian A1 - Niederberger, Andreas A1 - Pabel, Katharina A1 - Putzer, Max A1 - Roth-Isigkeit, David A1 - Seidler, Christoph A1 - Tiedemann, Paul A1 - Vasel, J. Justus A1 - Weiß, Norman T1 - MenschenRechtsMagazin : Informationen | Meinungen | Analysen N2 - Aus dem Inhalt: - Themenschwerpunkt: Menschenrechte und Staatsbürgerschaft - Gibt es Menschenrechte ohne Bürgerschaft? - Menschenwürde und Staatsbürgerschaft - Die General Comments des Menschenrechtsausschusses der Vereinten Nationen – ein Beitrag zur Rechtsentwicklung im Völkerrecht - Politische Selbstbestimmung als Menschenrecht und im Völkerrecht - Libyen und der von außen unterstützte Systemwechsel T3 - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen - 17.2012/2 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62122 SN - 1434-2820 VL - 17 IS - 2 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Pipek, Volkmar A1 - Stevens, Gunnar A1 - Veith, Michael A1 - Müller, Claudia A1 - Draxler, Sebastian T1 - Jede Software ist "Social" JF - Analyse Sozialer Netzwerke und Social Software Y1 - 2010 SN - 978-3-940019-26-4 SP - 199 EP - 233 PB - GITO CY - Berlin ER - TY - JOUR A1 - Muller, K. R. A1 - Ratsch, G. A1 - Sonnenburg, S. A1 - Mika, Sebastian A1 - Grimm, M. A1 - Heinrich, N. T1 - Classifying 'drug-likeness' with kernel-based learning methods N2 - In this article we report about a successful application of modern machine learning technology, namely Support Vector Machines, to the problem of assessing the 'drug-likeness' of a chemical from a given set of descriptors of the Substance. We were able to drastically improve the recent result by Byvatov et al. (2003) on this task and achieved an error rate of about 7% on unseen compounds using Support Vector Machines. We see a very high potential of such machine learning techniques for a variety of computational chemistry problems that occur in the drug discovery and drug design process Y1 - 2005 SN - 1549-9596 ER - TY - JOUR A1 - Walter, Juliane K. A1 - Rückert, Christine A1 - Voss, Martin A1 - Müller, Sebastian L. A1 - Piontek, Joerg A1 - Gast, Klaus A1 - Blasig, Ingolf E. T1 - The oligomerization of the coiled coil-domain of occluddin is redox sensitive N2 - The transmembrane tight junction protein occludin is sensitive to oxidative stress. Occludin oligomerizes; however, its function in the tight junction is unknown. The cytosolic C-terminal tail contains a coiled coil-domain and forms dimers contributing to the oligomerization. The regulation of the oligomerization remains unclear. As the domain area contains sulfhydryl residues, we tested the hypothesis that the dimerization of the coiled coil-domain depends on these residues. We showed that the dimerization is modulated by the thiol concentration in the low-millimolar range, which is relevant both for physiological and pathophysiological conditions. Masking the sulfhydryl residues in the fragment by covalent binding of 4-vinyl pyridine prevented the dimerization but did not affect its helical structure and cylindric shape. The data demonstrate, for the first time, that disulfide bridge formation of murine cystein 408 is involved in the dimerization. This process is redox-sensitive but the secondary structure of the domain is not. It is concluded that the dimerization of occludin may play a regulatory role in the tight junction assembly under physiological and pathological conditions. Y1 - 2009 UR - http://www3.interscience.wiley.com/cgi-bin/issn?DESCRIPTOR=PRINTISSN&VALUE=0077-8923 U6 - https://doi.org/10.1111/j.1749-6632.2009.04058.x SN - 0077-8923 ER - TY - JOUR A1 - Fabian, Benjamin A1 - Kunz, Steffen A1 - Konnegen, Marcel A1 - Müller, Sebastian A1 - Günther, Oliver T1 - Access control for semantic data federations in industrial product-lifecycle management JF - Computers in industry : an international, application oriented research journal N2 - Information integration across company borders becomes increasingly important for the success of product lifecycle management in industry and complex supply chains. Semantic technologies are about to play a crucial role in this integrative process. However, cross-company data exchange requires mechanisms to enable fine-grained access control definition and enforcement, preventing unauthorized leakage of confidential data across company borders. Currently available semantic repositories are not sufficiently equipped to satisfy this important requirement. This paper presents an infrastructure for controlled sharing of semantic data between cooperating business partners. First, we motivate the need for access control in semantic data federations by a case study in the industrial service sector. Furthermore, we present an architecture for controlling access to semantic repositories that is based on our newly developed SemForce security service. Finally, we show the practical feasibility of this architecture by an implementation and several performance experiments. KW - Access control KW - Data federation KW - Information integration KW - Product lifecycle management KW - Semantic data Y1 - 2012 U6 - https://doi.org/10.1016/j.compind.2012.08.015 SN - 0166-3615 VL - 63 IS - 9 SP - 930 EP - 940 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Zien, Alexander A1 - Rätsch, Gunnar A1 - Mika, Sebastian A1 - Schölkopf, Bernhard A1 - Lengauer, Thomas A1 - Müller, Klaus-Robert T1 - Engineering support vector machine kernels that recognize translation initiation sites Y1 - 2000 SN - 1367-4803 ER - TY - JOUR A1 - Rätsch, Gunnar A1 - Schölkopf, B. A1 - Smola, Alexander J. A1 - Mika, Sebastian A1 - Onoda, T. A1 - Müller, Klaus-Robert T1 - Robust ensemble learning Y1 - 2000 SN - 0-262-19448-1 ER - TY - BOOK A1 - Rätsch, Gunnar A1 - Schölkopf, B. A1 - Mika, Sebastian A1 - Müller, Klaus-Robert T1 - SVM and boosting : one class T3 - GMD-Report Y1 - 2000 VL - 119 PB - GMD-Forschungszentrum Informationstechnik CY - Sankt Augustin ER - TY - JOUR A1 - Rätsch, Gunnar A1 - Schölkopf, B. A1 - Smola, Alexander J. A1 - Müller, Klaus-Robert A1 - Mika, Sebastian T1 - V-Arc : ensemble learning in the preence of outliers Y1 - 2000 ER - TY - JOUR A1 - Mika, Sebastian A1 - Rätsch, Gunnar A1 - Weston, J. A1 - Schölkopf, B. A1 - Smola, Alexander J. A1 - Müller, Klaus-Robert T1 - Invariant feature extraction and classification in kernel spaces Y1 - 2000 ER - TY - JOUR A1 - Rätsch, Gunnar A1 - Schölkopf, B. A1 - Smola, Alexander J. A1 - Mika, Sebastian A1 - Onoda, T. A1 - Müller, Klaus-Robert T1 - Robust ensemble learning for data analysis Y1 - 2000 ER - TY - BOOK A1 - Scherbaum, Frank A1 - Mzhavanadze, Nana A1 - Arom, Simha A1 - Rosenzweig, Sebastian A1 - Müller, Meinard ED - Scherbaum, Frank T1 - Tonal Organization of the Erkomaishvili Dataset: Pitches, Scales, Melodies and Harmonies T3 - Computational Analysis Of Traditional Georgian Vocal Music N2 - In this study we examine the tonal organization of a series of recordings of liturgical chants, sung in 1966 by the Georgian master singer Artem Erkomaishvili. This dataset is the oldest corpus of Georgian chants from which the time synchronous F0-trajectories for all three voices have been reliably determined (Müller et al. 2017). It is therefore of outstanding importance for the understanding of the tuning principles of traditional Georgian vocal music. The aim of the present study is to use various computational methods to analyze what these recordings can contribute to the ongoing scientific dispute about traditional Georgian tuning systems. Starting point for the present analysis is the re-release of the original audio data together with estimated fundamental frequency (F0) trajectories for each of the three voices, beat annotations, and digital scores (Rosenzweig et al. 2020). We present synoptic models for the pitch and the harmonic interval distributions, which are the first of such models for which the complete Erkomaishvili dataset was used. We show that these distributions can be very compactly be expressed as Gaussian mixture models, anchored on discrete sets of pitch or interval values for the pitch and interval distributions, respectively. As part of our study we demonstrate that these pitch values, which we refer to as scale pitches, and which are determined as the mean values of the Gaussian mixture elements, define the scale degrees of the melodic sound scales which build the skeleton of Artem Erkomaishvili’s intonation. The observation of consistent pitch bending of notes in melodic phrases, which appear in identical form in a group of chants, as well as the observation of harmonically driven intonation adjustments, which are clearly documented for all pure harmonic intervals, demonstrate that Artem Erkomaishvili intentionally deviates from the scale pitch skeleton quite freely. As a central result of our study, we proof that this melodic freedom is always constrained by the attracting influence of the scale pitches. Deviations of the F0-values of individual note events from the scale pitches at one instance of time are compensated for in the subsequent melodic steps. This suggests a deviation-compensation mechanism at the core of Artem Erkomaishvili’s melody generation, which clearly honors the scales but still allows for a large degree of melodic flexibility. This model, which summarizes all partial aspects of our analysis, is consistent with the melodic scale models derived from the observed pitch distributions, as well as with the melodic and harmonic interval distributions. In addition to the tangible results of our work, we believe that our work has general implications for the determination of tuning models from audio data, in particular for non-tempered music. T3 - Computational Analysis Of Traditional Georgian Vocal Music - 1 KW - computational ethnomusicology KW - traditional Georgian music KW - Georgian chant KW - Artem Erkomaishvili KW - musical scales KW - computergestützte Musikethnologie KW - traditionelle Georgische Musik KW - Georgische liturgische Gesänge KW - Artem Erkomaishvili KW - musikalische Tonleitern Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-476141 SN - 2702-2641 IS - 1 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Fabian, Benjamin A1 - Kunz, Steffen A1 - Müller, Sebastian A1 - Günther, Oliver T1 - Secure federation of semantic information services JF - Decision support systems : DSS ; the international journal N2 - fundamental challenge for product-lifecycle management in collaborative value networks is to utilize the vast amount of product information available from heterogeneous sources in order to improve business analytics, decision support, and processes. This becomes even more challenging if those sources are distributed across multiple organizations. Federations of semantic information services, combining service-orientation and semantic technologies, provide a promising solution for this problem. However, without proper measures to establish information security, companies will be reluctant to join an information federation, which could lead to serious adoption barriers. Following the design science paradigm, this paper presents general objectives and a process for designing a secure federation of semantic information services. Furthermore, new as well as established security measures are discussed. Here, our contributions include an access-control enforcement system for semantic information services and a process for modeling access-control policies across organizations. In addition, a comprehensive security architecture is presented. An implementation of the architecture in the context of an application scenario and several performance experiments demonstrate the practical viability of our approach. KW - Information federation KW - Service orientation KW - Semantic web KW - Information security Y1 - 2013 U6 - https://doi.org/10.1016/j.dss.2012.05.049 SN - 0167-9236 VL - 55 IS - 1 SP - 385 EP - 398 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Müller, Sebastian A1 - Zech, Alraune A1 - Hesse, Falk T1 - ogs5py: APython-APIfor theOpenGeoSys5 Scientific Modeling Package JF - Groundwater : journal of the Association of Ground-Water Scientists and Engineers, a division of the National Ground Water Association N2 - High-performance numerical codes are an indispensable tool for hydrogeologists when modeling subsurface flow and transport systems. But as they are written in compiled languages, like C/C++ or Fortran, established software packages are rarely user-friendly, limiting a wider adoption of such tools. OpenGeoSys (OGS), an open-source, finite-element solver for thermo-hydro-mechanical-chemical processes in porous and fractured media, is no exception. Graphical user interfaces may increase usability, but do so at a dramatic reduction of flexibility and are difficult or impossible to integrate into a larger workflow. Python offers an optimal trade-off between these goals by providing a highly flexible, yet comparatively user-friendly environment for software applications. Hence, we introduceogs5py, a Python-API for the OpenGeoSys 5 scientific modeling package. It provides a fully Python-based representation of an OGS project, a large array of convenience functions for users to interact with OGS and connects OGS to the scientific and computational environment of Python. Y1 - 2021 U6 - https://doi.org/10.1111/gwat.13017 SN - 0017-467X SN - 1745-6584 VL - 59 IS - 1 SP - 117 EP - 122 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Müller, Sebastian T1 - Menschenrechtsmonitoring BT - unabhängiger Menschenrechtsschutz und sinnvolle Ergänzung zu den gerichtlichen Verfahren JF - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen N2 - Inhalt: I. Einleitung II. Was ist Menschenrechtsmonitoring? Eine begriffliche Analyse III. Wie ergänzt Menschenrechtsmonitoring bestehende Beschwerdemechanismen zum Schutz der Menschenrechte? IV. Ausblick: Grenzen und Zukunft des Menschenrechtsmonitoring V. Fazit Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-63907 SN - 1434-2820 VL - 17 IS - 2 SP - 211 EP - 226 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Köslin-Findeklee, Fabian A1 - Rizi, Vajiheh Safavi A1 - Becker, Martin A. A1 - Parra-Londono, Sebastian A1 - Arif, Muhammad A1 - Balazadeh, Salma A1 - Müller-Röber, Bernd A1 - Kunze, Reinhard A1 - Horst, Walter J. T1 - Transcriptomic analysis of nitrogen starvation- and cultivar-specific leaf senescence in winter oilseed rape (Brassica napus L.) JF - Plant science : an international journal of experimental plant biology N2 - High nitrogen (N) efficiency, characterized by high grain yield under N limitation, is an important agricultural trait in Brassica napus L. cultivars related to delayed senescence of older leaves during reproductive growth (a syndrome called stay-green). The aim of this study was thus to identify genes whose expression is specifically altered during N starvation-induced leaf senescence and that can be used as markers to distinguish cultivars at early stages of senescence prior to chlorophyll loss. To this end, the transcriptomes of leaves of two B. napus cultivars differing in stay-green characteristics and N efficiency were analyzed 4 days after the induction of senescence by either N starvation, leaf shading or detaching. In addition to N metabolism genes, N starvation mostly (and specifically) repressed genes related to photosynthesis, photorespiration and cell-wall structure, while genes related to mitochondrial electron transport and flavonoid biosynthesis were predominately up-regulated. A kinetic study over a period of 12 days with four B. napus cultivars differing in their stay-green characteristics confirmed the cultivar-specific regulation of six genes in agreement with their senescence behavior: the senescence regulator ANAC029, the anthocyanin synthesis-related genes ANS and DFR-like1, the ammonium transporter AMT1:4, the ureide transporter UPSS, and SPS1 involved in sucrose biosynthesis. The identified genes represent markers for the detection of cultivar-specific differences in N starvation-induced leaf senescence and can thus be employed as valuable tools in B. napus breeding. (C) 2015 Elsevier Ireland Ltd. All rights reserved. KW - Brassica napus KW - Genotypic differences KW - Leaf senescence KW - Molecular marker KW - N efficiency KW - Stay-green Y1 - 2015 U6 - https://doi.org/10.1016/j.plantsci.2014.11.018 SN - 0168-9452 VL - 233 SP - 174 EP - 185 PB - Elsevier CY - Clare ER - TY - JOUR A1 - Omranian, Nooshin A1 - Klie, Sebastian A1 - Müller-Röber, Bernd A1 - Nikoloski, Zoran T1 - Network-based segmentation of biological multivariate time series JF - PLoS one N2 - Molecular phenotyping technologies (e.g., transcriptomics, proteomics, and metabolomics) offer the possibility to simultaneously obtain multivariate time series (MTS) data from different levels of information processing and metabolic conversions in biological systems. As a result, MTS data capture the dynamics of biochemical processes and components whose couplings may involve different scales and exhibit temporal changes. Therefore, it is important to develop methods for determining the time segments in MTS data, which may correspond to critical biochemical events reflected in the coupling of the system's components. Here we provide a novel network-based formalization of the MTS segmentation problem based on temporal dependencies and the covariance structure of the data. We demonstrate that the problem of partitioning MTS data into k segments to maximize a distance function, operating on polynomially computable network properties, often used in analysis of biological network, can be efficiently solved. To enable biological interpretation, we also propose a breakpoint-penalty (BP-penalty) formulation for determining MTS segmentation which combines a distance function with the number/length of segments. Our empirical analyses of synthetic benchmark data as well as time-resolved transcriptomics data from the metabolic and cell cycles of Saccharomyces cerevisiae demonstrate that the proposed method accurately infers the phases in the temporal compartmentalization of biological processes. In addition, through comparison on the same data sets, we show that the results from the proposed formalization of the MTS segmentation problem match biological knowledge and provide more rigorous statistical support in comparison to the contending state-of-the-art methods. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0062974 SN - 1932-6203 VL - 8 IS - 5 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Balazadeh, Salma A1 - Schildhauer, Joerg A1 - Araujo, Wagner L. A1 - Munne-Bosch, Sergi A1 - Fernie, Alisdair R. A1 - Proost, Sebastian A1 - Humbeck, Klaus A1 - Müller-Röber, Bernd T1 - Reversal of senescence by N resupply to N-starved Arabidopsis thaliana: transcriptomic and metabolomic consequences JF - Journal of experimental botany N2 - Leaf senescence is a developmentally controlled process, which is additionally modulated by a number of adverse environmental conditions. Nitrogen shortage is a well-known trigger of precocious senescence in many plant species including crops, generally limiting biomass and seed yield. However, leaf senescence induced by nitrogen starvation may be reversed when nitrogen is resupplied at the onset of senescence. Here, the transcriptomic, hormonal, and global metabolic rearrangements occurring during nitrogen resupply-induced reversal of senescence in Arabidopsis thaliana were analysed. The changes induced by senescence were essentially in keeping with those previously described; however, these could, by and large, be reversed. The data thus indicate that plants undergoing senescence retain the capacity to sense and respond to the availability of nitrogen nutrition. The combined data are discussed in the context of the reversibility of the senescence programme and the evolutionary benefit afforded thereby. Future prospects for understanding and manipulating this process in both Arabidopsis and crop plants are postulated. KW - Arabidopsis KW - gene expression KW - metabolomics KW - nitrogen limitation KW - senescence KW - transcriptome Y1 - 2014 U6 - https://doi.org/10.1093/jxb/eru119 SN - 0022-0957 SN - 1460-2431 VL - 65 IS - 14 SP - 3975 EP - 3992 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Proost, Sebastian A1 - Van Bel, Michiel A1 - Vaneechoutte, Dries A1 - Van de Peer, Yves A1 - Inze, Dirk A1 - Müller-Röber, Bernd A1 - Vandepoele, Klaas T1 - PLAZA 3.0: an access point for plant comparative genomics JF - Nucleic acids research N2 - Comparative sequence analysis has significantly altered our view on the complexity of genome organization and gene functions in different kingdoms. PLAZA 3.0 is designed to make comparative genomics data for plants available through a user-friendly web interface. Structural and functional annotation, gene families, protein domains, phylogenetic trees and detailed information about genome organization can easily be queried and visualized. Compared with the first version released in 2009, which featured nine organisms, the number of integrated genomes is more than four times higher, and now covers 37 plant species. The new species provide a wider phylogenetic range as well as a more in-depth sampling of specific clades, and genomes of additional crop species are present. The functional annotation has been expanded and now comprises data from Gene Ontology, MapMan, UniProtKB/Swiss-Prot, PlnTFDB and PlantTFDB. Furthermore, we improved the algorithms to transfer functional annotation from well-characterized plant genomes to other species. The additional data and new features make PLAZA 3.0 (http://bioinformatics.psb.ugent.be/plaza/) a versatile and comprehensible resource for users wanting to explore genome information to study different aspects of plant biology, both in model and non-model organisms. Y1 - 2015 U6 - https://doi.org/10.1093/nar/gku986 SN - 0305-1048 SN - 1362-4962 VL - 43 IS - D1 SP - D974 EP - D981 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Omidbakhshfard, Mohammad Amin A1 - Proost, Sebastian A1 - Fujikura, Ushio A1 - Müller-Röber, Bernd T1 - Growth-Regulating Factors (GRFs): A Small Transcription Factor Family with Important Functions in Plant Biology JF - Molecular plant N2 - Growth-regulating factors (GRFs) are plant-specific transcription factors that were originally identified for their roles in stem and leaf development, but recent studies highlight them to be similarly important for other central developmental processes including flower and seed formation, root development, and the coordination of growth processes under adverse environmental conditions. The expression of several GRFs is controlled by microRNA miR396, and the GRF-miRNA396 regulatory module appears to be central to several of these processes. In addition, transcription factors upstream of GRFs and miR396 have been discovered, and gradually downstream target genes of GRFs are being unraveled. Here, we review the current knowledge of the biological functions performed by GRFs and survey available molecular data to illustrate how they exert their roles at the cellular level. KW - abiotic stress KW - chromatin remodeling KW - flower development KW - growth regulation KW - leaf development KW - miRNA Y1 - 2015 U6 - https://doi.org/10.1016/j.molp.2015.01.013 SN - 1674-2052 SN - 1752-9867 VL - 8 IS - 7 SP - 998 EP - 1010 PB - Cell Press CY - Cambridge ER - TY - JOUR A1 - Read, Betsy A. A1 - Kegel, Jessica A1 - Klute, Mary J. A1 - Kuo, Alan A1 - Lefebvre, Stephane C. A1 - Maumus, Florian A1 - Mayer, Christoph A1 - Miller, John A1 - Monier, Adam A1 - Salamov, Asaf A1 - Young, Jeremy A1 - Aguilar, Maria A1 - Claverie, Jean-Michel A1 - Frickenhaus, Stephan A1 - Gonzalez, Karina A1 - Herman, Emily K. A1 - Lin, Yao-Cheng A1 - Napier, Johnathan A1 - Ogata, Hiroyuki A1 - Sarno, Analissa F. A1 - Shmutz, Jeremy A1 - Schroeder, Declan A1 - de Vargas, Colomban A1 - Verret, Frederic A1 - von Dassow, Peter A1 - Valentin, Klaus A1 - Van de Peer, Yves A1 - Wheeler, Glen A1 - Dacks, Joel B. A1 - Delwiche, Charles F. A1 - Dyhrman, Sonya T. A1 - Glöckner, Gernot A1 - John, Uwe A1 - Richards, Thomas A1 - Worden, Alexandra Z. A1 - Zhang, Xiaoyu A1 - Grigoriev, Igor V. A1 - Allen, Andrew E. A1 - Bidle, Kay A1 - Borodovsky, M. A1 - Bowler, C. A1 - Brownlee, Colin A1 - Cock, J. Mark A1 - Elias, Marek A1 - Gladyshev, Vadim N. A1 - Groth, Marco A1 - Guda, Chittibabu A1 - Hadaegh, Ahmad A1 - Iglesias-Rodriguez, Maria Debora A1 - Jenkins, J. A1 - Jones, Bethan M. A1 - Lawson, Tracy A1 - Leese, Florian A1 - Lindquist, Erika A1 - Lobanov, Alexei A1 - Lomsadze, Alexandre A1 - Malik, Shehre-Banoo A1 - Marsh, Mary E. A1 - Mackinder, Luke A1 - Mock, Thomas A1 - Müller-Röber, Bernd A1 - Pagarete, Antonio A1 - Parker, Micaela A1 - Probert, Ian A1 - Quesneville, Hadi A1 - Raines, Christine A1 - Rensing, Stefan A. A1 - Riano-Pachon, Diego Mauricio A1 - Richier, Sophie A1 - Rokitta, Sebastian A1 - Shiraiwa, Yoshihiro A1 - Soanes, Darren M. A1 - van der Giezen, Mark A1 - Wahlund, Thomas M. A1 - Williams, Bryony A1 - Wilson, Willie A1 - Wolfe, Gordon A1 - Wurch, Louie L. T1 - Pan genome of the phytoplankton Emiliania underpins its global distribution JF - Nature : the international weekly journal of science N2 - Coccolithophores have influenced the global climate for over 200 million years(1). These marine phytoplankton can account for 20 per cent of total carbon fixation in some systems(2). They form blooms that can occupy hundreds of thousands of square kilometres and are distinguished by their elegantly sculpted calcium carbonate exoskeletons (coccoliths), rendering them visible from space(3). Although coccolithophores export carbon in the form of organic matter and calcite to the sea floor, they also release CO2 in the calcification process. Hence, they have a complex influence on the carbon cycle, driving either CO2 production or uptake, sequestration and export to the deep ocean(4). Here we report the first haptophyte reference genome, from the coccolithophore Emiliania huxleyi strain CCMP1516, and sequences from 13 additional isolates. Our analyses reveal a pan genome (core genes plus genes distributed variably between strains) probably supported by an atypical complement of repetitive sequence in the genome. Comparisons across strains demonstrate that E. huxleyi, which has long been considered a single species, harbours extensive genome variability reflected in different metabolic repertoires. Genome variability within this species complex seems to underpin its capacity both to thrive in habitats ranging from the equator to the subarctic and to form large-scale episodic blooms under a wide variety of environmental conditions. Y1 - 2013 U6 - https://doi.org/10.1038/nature12221 SN - 0028-0836 SN - 1476-4687 VL - 499 IS - 7457 SP - 209 EP - 213 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Schweppe, Robert A1 - Thober, Stephan A1 - Müller, Sebastian A1 - Kelbling, Matthias A1 - Kumar, Rohini A1 - Attinger, Sabine A1 - Samaniego, Luis T1 - MPR 1.0: a stand-alone multiscale parameter regionalization tool for improved parameter estimation of land surface models JF - Geoscientific model development : an interactive open access journal of the European Geosciences Union N2 - Distributed environmental models such as land surface models (LSMs) require model parameters in each spatial modeling unit (e.g., grid cell), thereby leading to a high-dimensional parameter space. One approach to decrease the dimensionality of the parameter space in these models is to use regularization techniques. One such highly efficient technique is the multiscale parameter regionalization (MPR) framework that translates high-resolution predictor variables (e.g., soil textural properties) into model parameters (e.g., porosity) via transfer functions (TFs) and upscaling operators that are suitable for every modeled process. This framework yields seamless model parameters at multiple scales and locations in an effective manner. However, integration of MPR into existing modeling workflows has been hindered thus far by hard-coded configurations and non-modular software designs. For these reasons, we redesigned MPR as a model-agnostic, stand-alone tool. It is a useful software for creating graphs of NetCDF variables, wherein each node is a variable and the links consist of TFs and/or upscaling operators. In this study, we present and verify our tool against a previous version, which was implemented in the mesoscale hydrologic model (mHM; https://www.ufz.de/mhm, last access: 16 January 2022). By using this tool for the generation of continental-scale soil hydraulic parameters applicable to different models (Noah-MP and HTESSEL), we showcase its general functionality and flexibility. Further, using model parameters estimated by the MPR tool leads to significant changes in long-term estimates of evapotranspiration, as compared to their default parameterizations. For example, a change of up to 25 % in long-term evapotranspiration flux is observed in Noah-MP and HTESSEL in the Mississippi River basin. We postulate that use of the stand-alone MPR tool will considerably increase the transparency and reproducibility of the parameter estimation process in distributed (environmental) models. It will also allow a rigorous uncertainty estimation related to the errors of the predictors (e.g., soil texture fields), transfer function and its parameters, and remapping (or upscaling) algorithms. Y1 - 2022 U6 - https://doi.org/10.5194/gmd-15-859-2022 SN - 1991-959X SN - 1991-9603 VL - 15 IS - 2 SP - 859 EP - 882 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Diluiso, Francesca A1 - Walk, Paula A1 - Manych, Niccolo A1 - Cerutti, Nicola A1 - Chipiga, Vladislav A1 - Workman, Annabelle A1 - Ayas, Ceren A1 - Cui, Ryna Yiyun A1 - Cui, Diyang A1 - Song, Kaihui A1 - Banisch, Lucy A. A1 - Moretti, Nikolaj A1 - Callaghan, Max W. A1 - Clarke, Leon A1 - Creutzig, Felix A1 - Hilaire, Jerome A1 - Jotzo, Frank A1 - Kalkuhl, Matthias A1 - Lamb, William F. A1 - Löschel, Andreas A1 - Müller-Hansen, Finn A1 - Nemet, Gregory F. A1 - Oei, Pao-Yu A1 - Sovacool, Benjamin K. A1 - Steckel, Jan Christoph A1 - Thomas, Sebastian A1 - Wiseman, John A1 - Minx, Jan C. T1 - Coal transitions - part 1 BT - a systematic map and review of case study learnings from regional, national, and local coal phase-out experiences JF - Environmental research letters N2 - A rapid coal phase-out is needed to meet the goals of the Paris Agreement, but is hindered by serious challenges ranging from vested interests to the risks of social disruption. To understand how to organize a global coal phase-out, it is crucial to go beyond cost-effective climate mitigation scenarios and learn from the experience of previous coal transitions. Despite the relevance of the topic, evidence remains fragmented throughout different research fields, and not easily accessible. To address this gap, this paper provides a systematic map and comprehensive review of the literature on historical coal transitions. We use computer-assisted systematic mapping and review methods to chart and evaluate the available evidence on historical declines in coal production and consumption. We extracted a dataset of 278 case studies from 194 publications, covering coal transitions in 44 countries and ranging from the end of the 19th century until 2021. We find a relatively recent and rapidly expanding body of literature reflecting the growing importance of an early coal phase-out in scientific and political debates. Previous evidence has primarily focused on the United Kingdom, the United States, and Germany, while other countries that experienced large coal declines, like those in Eastern Europe, are strongly underrepresented. An increasing number of studies, mostly published in the last 5 years, has been focusing on China. Most of the countries successfully reducing coal dependency have undergone both demand-side and supply-side transitions. This supports the use of policy approaches targeting both demand and supply to achieve a complete coal phase-out. From a political economy perspective, our dataset highlights that most transitions are driven by rising production costs for coal, falling prices for alternative energies, or local environmental concerns, especially regarding air pollution. The main challenges for coal-dependent regions are structural change transformations, in particular for industry and labor. Rising unemployment is the most largely documented outcome in the sample. Policymakers at multiple levels are instrumental in facilitating coal transitions. They rely mainly on regulatory instruments to foster the transitions and compensation schemes or investment plans to deal with their transformative processes. Even though many models suggest that coal phase-outs are among the low-hanging fruits on the way to climate neutrality and meeting the international climate goals, our case studies analysis highlights the intricate political economy at work that needs to be addressed through well-designed and just policies. KW - climate change mitigation KW - coal transitions KW - evidence synthesis KW - political economy KW - systematic map Y1 - 2021 U6 - https://doi.org/10.1088/1748-9326/ac1b58 SN - 1748-9326 VL - 16 IS - 11 PB - Institute of Physics Publishing (IOP) CY - Bristol ER - TY - JOUR A1 - Omranian, Nooshin A1 - Kleessen, Sabrina A1 - Tohge, Takayuki A1 - Klie, Sebastian A1 - Basler, Georg A1 - Müller-Röber, Bernd A1 - Fernie, Alisdair R. A1 - Nikoloski, Zoran T1 - Differential metabolic and coexpression networks of plant metabolism JF - Trends in plant science N2 - Recent analyses have demonstrated that plant metabolic networks do not differ in their structural properties and that genes involved in basic metabolic processes show smaller coexpression than genes involved in specialized metabolism. By contrast, our analysis reveals differences in the structure of plant metabolic networks and patterns of coexpression for genes in (non)specialized metabolism. Here we caution that conclusions concerning the organization of plant metabolism based on network-driven analyses strongly depend on the computational approaches used. KW - plant specialized metabolism KW - metabolic networks KW - gene coexpression KW - differential network analysis Y1 - 2015 U6 - https://doi.org/10.1016/j.tplants.2015.02.002 SN - 1360-1385 VL - 20 IS - 5 SP - 266 EP - 268 PB - Elsevier CY - London ER - TY - JOUR A1 - Zech, Christina A1 - Stein, Monika A1 - Haberer, Anke A1 - Böhne, Alexander A1 - Müller-Röber, Bernd A1 - Heinig, Angela A1 - Raehse, Sebastian T1 - Portal = Existenzgründung: Ein Sprung ins kalte Wasser BT - Die Potsdamer Universitätszeitung N2 - Aus dem Inhalt: Existenzgründung: Ein Sprung ins kalte Wasser -Bernd Walz über Wettbewerbsfähigkeit und Nachwuchsförderung -Gertrud Lehnert über Mode bei Marcel Proust -Juniorprofessor Jens Eisert über Quanteninformation T3 - Portal: Das Potsdamer Universitätsmagazin - 03-04/2003 Y1 - 2003 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-501536 SN - 1618-6893 VL - 2003 ER - TY - JOUR A1 - Kirchhecker, Sarah A1 - Tröger-Müller, Steffen A1 - Bake, Sebastian A1 - Antonietti, Markus A1 - Taubert, Andreas A1 - Esposito, Davido T1 - Renewable pyridinium ionic liquids from the continuous hydrothermal decarboxylation of furfural-amino acid derived pyridinium zwitterions JF - Green chemistry N2 - Fully renewable pyridinium ionic liquids were synthesised via the hydrothermal decarboxylation of pyridinium zwitterions derived from furfural and amino acids in flow. The functionality of the resulting ionic liquid (IL) can be tuned by choice of different amino acids as well as different natural carboxylic acids as the counterions. A representative member of this new class of ionic liquids was successfully used for the synthesis of ionogels and as a solvent for the Heck coupling. Y1 - 2015 U6 - https://doi.org/10.1039/c5gc00913h SN - 1463-9262 SN - 1463-9270 VL - 8 IS - 17 SP - 4151 EP - 4156 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Kirchhecker, Sarah A1 - Tröger-Müller, Steffen A1 - Bake, Sebastian A1 - Antonietti, Markus A1 - Taubert, Andreas A1 - Esposito, Davide T1 - Renewable pyridinium ionic liquids from the continuous hydrothermal decarboxylation of furfural-amino acid derived pyridinium zwitterions JF - Green chemistry : an international journal and green chemistry resource N2 - Fully renewable pyridinium ionic liquids were synthesised via the hydrothermal decarboxylation of pyridinium zwitterions derived from furfural and amino acids in flow. The functionality of the resulting ionic liquid (IL) can be tuned by choice of different amino acids as well as different natural carboxylic acids as the counter-ions. A representative member of this new class of ionic liquids was successfully used for the synthesis of ionogels and as a solvent for the Heck coupling. Y1 - 2015 U6 - https://doi.org/10.1039/c5gc00913h SN - 1463-9262 SN - 1463-9270 VL - 17 IS - 8 SP - 4151 EP - 4156 PB - Royal Society of Chemistry CY - Cambridge ER - TY - GEN A1 - Kirchhecker, Sarah A1 - Tröger-Müller, Steffen A1 - Bake, Sebastian A1 - Antonietti, Markus A1 - Taubert, Andreas A1 - Esposito, Davido T1 - Renewable pyridinium ionic liquids from the continuous hydrothermal decarboxylation of furfural-amino acid derived pyridinium zwitterions N2 - Fully renewable pyridinium ionic liquids were synthesised via the hydrothermal decarboxylation of pyridinium zwitterions derived from furfural and amino acids in flow. The functionality of the resulting ionic liquid (IL) can be tuned by choice of different amino acids as well as different natural carboxylic acids as the counterions. A representative member of this new class of ionic liquids was successfully used for the synthesis of ionogels and as a solvent for the Heck coupling. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 198 Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-81390 ER - TY - JOUR A1 - Kyriakos, Konstantinos A1 - Philipp, Martine A1 - Adelsberger, Joseph A1 - Jaksch, Sebastian A1 - Berezkin, Anatoly V. A1 - Lugo, Dersy M. A1 - Richtering, Walter A1 - Grillo, Isabelle A1 - Miasnikova, Anna A1 - Laschewsky, André A1 - Müller-Buschbaum, Peter A1 - Papadakis, Christine M. T1 - Cononsolvency of water/methanol mixtures for PNIPAM and PS-b-PNIPAM: pathway of aggregate formation investigated using time-resolved SANS JF - Macromolecules : a publication of the American Chemical Society N2 - We investigate the cononsolvency effect of poly(N-isopropylacrylamide) (PNIPAM) in mixtures of water and methanol. Two systems are studied: micellar solutions of polystyrene-b-poly(N-isopropylacrylamide) (PS-b-PNIPAM) diblock copolymers and, as a reference, solutions of PNIPAM homopolymers, both at a concentration of 20 mg/mL in DO. Using a stopped-flow instrument, fully deuterated methanol was rapidly added to these solutions at volume fractions between 10 and 20%. Time-resolved turbidimetry revealed aggregate formation within 10-100 s. The structural changes on mesoscopic length scales were followed by time-resolved small-angle neutron scattering (TR-SANS) with a time resolution of 0.1 s. In both systems, the pathway of the aggregation depends on the content of deuterated methanol; however, it is fundamentally different for homopolymer and diblock copolymer solutions: In the former, very large aggregates (>150 nm) are formed within the dead time of the setup, gradient appears at their surface in the late stages. In contrast, the growth of the aggregates in the latter system features different regimes, and the final aggregate size is 50 nm, thus much smaller than for the homopolymer. For the diblock copolymer, the time dependence of the aggregate radius can be described by two models: In the initial stage, the diffusion-limited coalescence model describes the data well; however, the resulting coalescence time is unreasonably high. In the late stage, a logarithmic coalescence model based on an energy barrier which is proportional to the aggregate radius is successfully applied. and a concentration Y1 - 2014 U6 - https://doi.org/10.1021/ma501434e SN - 0024-9297 SN - 1520-5835 VL - 47 IS - 19 SP - 6867 EP - 6879 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Müller, Sebastian A1 - Schüler, Lennart A1 - Zech, Alraune A1 - Heße, Falk T1 - GSTools v1.3: a toolbox for geostatistical modelling in Python JF - Geoscientific model development : an interactive open access journal of the European Geosciences Union N2 - Geostatistics as a subfield of statistics accounts for the spatial correlations encountered in many applications of, for example, earth sciences. Valuable information can be extracted from these correlations, also helping to address the often encountered burden of data scarcity. Despite the value of additional data, the use of geostatistics still falls short of its potential. This problem is often connected to the lack of user-friendly software hampering the use and application of geostatistics. We therefore present GSTools, a Python-based software suite for solving a wide range of geostatistical problems. We chose Python due to its unique balance between usability, flexibility, and efficiency and due to its adoption in the scientific community. GSTools provides methods for generating random fields; it can perform kriging, variogram estimation and much more. We demonstrate its abilities by virtue of a series of example applications detailing their use. Y1 - 2022 U6 - https://doi.org/10.5194/gmd-15-3161-2022 SN - 1991-959X SN - 1991-9603 VL - 15 IS - 7 SP - 3161 EP - 3182 PB - Copernicus CY - Göttingen ER - TY - GEN A1 - Thieken, Annegret A1 - Bessel, Tina A1 - Kienzler, Sarah A1 - Kreibich, Heidi A1 - Müller, Meike A1 - Pisi, Sebastian A1 - Schröter, Kai T1 - The flood of June 2013 in Germany BT - how much do we know about its impacts? T2 - National Hazards Earth System Science N2 - In June 2013, widespread flooding and consequent damage and losses occurred in Central Europe, especially in Germany. This paper explores what data are available to investigate the adverse impacts of the event, what kind of information can be retrieved from these data and how well data and information fulfil requirements that were recently proposed for disaster reporting on the European and international levels. In accordance with the European Floods Directive (2007/60/EC), impacts on human health, economic activities (and assets), cultural heritage and the environment are described on the national and sub-national scale. Information from governmental reports is complemented by communications on traffic disruptions and surveys of flood-affected residents and companies. Overall, the impacts of the flood event in 2013 were manifold. The study reveals that flood-affected residents suffered from a large range of impacts, among which mental health and supply problems were perceived more seriously than financial losses. The most frequent damage type among affected companies was business interruption. This demonstrates that the current scientific focus on direct (financial) damage is insufficient to describe the overall impacts and severity of flood events. The case further demonstrates that procedures and standards for impact data collection in Germany are widely missing. Present impact data in Germany are fragmentary, heterogeneous, incomplete and difficult to access. In order to fulfil, for example, the monitoring and reporting requirements of the Sendai Framework for Disaster Risk Reduction 2015–2030 that was adopted in March 2015 in Sendai, Japan, more efforts on impact data collection are needed. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-97207 ER - TY - GEN A1 - Thieken, Annegret A1 - Kienzler, Sarah A1 - Kreibich, Heidi A1 - Kuhlicke, Christian A1 - Kunz, Michael A1 - Mühr, Bernhard A1 - Müller, Meike A1 - Otto, Antje A1 - Petrow, Theresia A1 - Pisi, Sebastian A1 - Schröter, Kai T1 - Review of the flood risk management system in Germany after the major flood in 2013 N2 - Widespread flooding in June 2013 caused damage costs of €6 to 8 billion in Germany, and awoke many memories of the floods in August 2002, which resulted in total damage of €11.6 billion and hence was the most expensive natural hazard event in Germany up to now. The event of 2002 does, however, also mark a reorientation toward an integrated flood risk management system in Germany. Therefore, the flood of 2013 offered the opportunity to review how the measures that politics, administration, and civil society have implemented since 2002 helped to cope with the flood and what still needs to be done to achieve effective and more integrated flood risk management. The review highlights considerable improvements on many levels, in particular (1) an increased consideration of flood hazards in spatial planning and urban development, (2) comprehensive property-level mitigation and preparedness measures, (3) more effective flood warnings and improved coordination of disaster response, and (4) a more targeted maintenance of flood defense systems. In 2013, this led to more effective flood management and to a reduction of damage. Nevertheless, important aspects remain unclear and need to be clarified. This particularly holds for balanced and coordinated strategies for reducing and overcoming the impacts of flooding in large catchments, cross-border and interdisciplinary cooperation, the role of the general public in the different phases of flood risk management, as well as a transparent risk transfer system. Recurring flood events reveal that flood risk management is a continuous task. Hence, risk drivers, such as climate change, land-use changes, economic developments, or demographic change and the resultant risks must be investigated at regular intervals, and risk reduction strategies and processes must be reassessed as well as adapted and implemented in a dialogue with all stakeholders. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 294 KW - August 2002 flood KW - Central Europe KW - Floods Directive KW - June 2013 flood KW - governance KW - risk management cycle Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-100600 SN - 1866-8372 ER - TY - JOUR A1 - Thieken, Annegret A1 - Bessel, Tina A1 - Kienzler, Sarah A1 - Kreibich, Heidi A1 - Müller, Meike A1 - Pisi, Sebastian A1 - Schröter, Kai T1 - The flood of June 2013 in Germany BT - how much do we know about its impacts? JF - National Hazards Earth System Science N2 - In June 2013, widespread flooding and consequent damage and losses occurred in Central Europe, especially in Germany. This paper explores what data are available to investigate the adverse impacts of the event, what kind of information can be retrieved from these data and how well data and information fulfil requirements that were recently proposed for disaster reporting on the European and international levels. In accordance with the European Floods Directive (2007/60/EC), impacts on human health, economic activities (and assets), cultural heritage and the environment are described on the national and sub-national scale. Information from governmental reports is complemented by communications on traffic disruptions and surveys of flood-affected residents and companies. Overall, the impacts of the flood event in 2013 were manifold. The study reveals that flood-affected residents suffered from a large range of impacts, among which mental health and supply problems were perceived more seriously than financial losses. The most frequent damage type among affected companies was business interruption. This demonstrates that the current scientific focus on direct (financial) damage is insufficient to describe the overall impacts and severity of flood events. The case further demonstrates that procedures and standards for impact data collection in Germany are widely missing. Present impact data in Germany are fragmentary, heterogeneous, incomplete and difficult to access. In order to fulfil, for example, the monitoring and reporting requirements of the Sendai Framework for Disaster Risk Reduction 2015–2030 that was adopted in March 2015 in Sendai, Japan, more efforts on impact data collection are needed. Y1 - 2016 U6 - https://doi.org/10.5194/nhess-16-1519-2016 IS - 16 SP - 1519 EP - 1540 PB - Copernicus Publications CY - Göttingen ER - TY - BOOK A1 - Thieken, Annegret A1 - Bessel, Tina A1 - Callsen, Ines A1 - Falter, Daniela A1 - Hasan, Issa A1 - Kienzler, Sarah A1 - Kox, Thomas A1 - Kreibich, Heidi A1 - Kuhlicke, Christian A1 - Kunz, Michael A1 - Matthias, Max A1 - Meyer, Volker A1 - Mühr, Bernhard A1 - Müller, Meike A1 - Otto, Antje A1 - Pech, Ina A1 - Petrow, Theresia A1 - Pisi, Sebastian A1 - Rother, Karl-Heinz A1 - Schröter, Kai T1 - Das Hochwasser im Juni 2013 BT - Bewährungsprobe für das Hochwasserrisikomanagement in Deutschland T3 - Schriftenreihe des DKKV ; 53 Y1 - 2015 SN - 978-3-933181-62-6 PB - Deutsches Komitee Katastrophenvorsorge CY - Bonn ER - TY - JOUR A1 - Müller, Meike A1 - Bessel, Tina A1 - Pisi, Sebastian A1 - Kreibich, Heidi A1 - Thieken, Annegret T1 - Auswirkungen und Schäden JF - Das Hochwasser im Juni 2013 : Bewährungsprobe für das Hochwasserrisikomanagement in Deutschland Y1 - 2015 SN - 978-3-933181-62-6 SP - 31 EP - 45 ER - TY - JOUR A1 - Thieken, Annegret A1 - Kienzler, Sarah A1 - Kreibich, Heidi A1 - Kuhlicke, Christian A1 - Kunz, Michael A1 - Mühr, Bernhard A1 - Müller, Meike A1 - Otto, Antje A1 - Petrow, Theresia A1 - Pisi, Sebastian A1 - Schröter, Kai T1 - Review of the flood risk management system in Germany after the major flood in 2013 JF - Ecology and society : E&S ; a journal of integrative science for resilience and sustainability N2 - Widespread flooding in June 2013 caused damage costs of €6 to 8 billion in Germany, and awoke many memories of the floods in August 2002, which resulted in total damage of €11.6 billion and hence was the most expensive natural hazard event in Germany up to now. The event of 2002 does, however, also mark a reorientation toward an integrated flood risk management system in Germany. Therefore, the flood of 2013 offered the opportunity to review how the measures that politics, administration, and civil society have implemented since 2002 helped to cope with the flood and what still needs to be done to achieve effective and more integrated flood risk management. The review highlights considerable improvements on many levels, in particular (1) an increased consideration of flood hazards in spatial planning and urban development, (2) comprehensive property-level mitigation and preparedness measures, (3) more effective flood warnings and improved coordination of disaster response, and (4) a more targeted maintenance of flood defense systems. In 2013, this led to more effective flood management and to a reduction of damage. Nevertheless, important aspects remain unclear and need to be clarified. This particularly holds for balanced and coordinated strategies for reducing and overcoming the impacts of flooding in large catchments, cross-border and interdisciplinary cooperation, the role of the general public in the different phases of flood risk management, as well as a transparent risk transfer system. Recurring flood events reveal that flood risk management is a continuous task. Hence, risk drivers, such as climate change, land-use changes, economic developments, or demographic change and the resultant risks must be investigated at regular intervals, and risk reduction strategies and processes must be reassessed as well as adapted and implemented in a dialogue with all stakeholders. KW - August 2002 flood KW - Central Europe KW - Floods Directive KW - governance KW - June 2013 flood KW - risk management cycle Y1 - 2016 U6 - https://doi.org/10.5751/ES-08547-210251 SN - 1708-3087 SN - 1195-5449 VL - 21 IS - 2 PB - Resilience Alliance CY - Wolfville, NS ER - TY - JOUR A1 - Thieken, Annegret A1 - Otto, Antje A1 - Pisi, Sebastian A1 - Petrow, Theresia A1 - Kreibich, Heidi A1 - Kuhlicke, Christian A1 - Schröter, Kai A1 - Kienzler, Sarah A1 - Müller, Meike T1 - Schlussfolgerungen und Empfehlungen JF - Das Hochwasser im Juni 2013 : Bewährungsprobe für das Hochwasserrisikomanagement in Deutschland Y1 - 2015 SN - 978-3-933181-62-6 SP - 184 EP - 196 PB - Deutsches Komitee Katastrophenvorsorge CY - Bonn ER - TY - JOUR A1 - Lai, Huagui A1 - Luo, Jincheng A1 - Zwirner, Yannick A1 - Olthof, Selina A1 - Wieczorek, Alexander A1 - Ye, Fangyuan A1 - Jeangros, Quentin A1 - Yin, Xinxing A1 - Akhundova, Fatima A1 - Ma, Tianshu A1 - He, Rui A1 - Kothandaraman, Radha K. A1 - Chin, Xinyu A1 - Gilshtein, Evgeniia A1 - Muller, Andre A1 - Wang, Changlei A1 - Thiesbrummel, Jarla A1 - Siol, Sebastian A1 - Prieto, Jose Marquez A1 - Unold, Thomas A1 - Stolterfoht, Martin A1 - Chen, Cong A1 - Tiwari, Ayodhya N. A1 - Zhao, Dewei A1 - Fu, Fan T1 - High-performance flexible all-Perovskite tandem solar cells with reduced V-OC-deficit in wide-bandgap subcell JF - Advanced energy materials N2 - Among various types of perovskite-based tandem solar cells (TSCs), all-perovskite TSCs are of particular attractiveness for building- and vehicle-integrated photovoltaics, or space energy areas as they can be fabricated on flexible and lightweight substrates with a very high power-to-weight ratio. However, the efficiency of flexible all-perovskite tandems is lagging far behind their rigid counterparts primarily due to the challenges in developing efficient wide-bandgap (WBG) perovskite solar cells on the flexible substrates as well as their low open-circuit voltage (V-OC). Here, it is reported that the use of self-assembled monolayers as hole-selective contact effectively suppresses the interfacial recombination and allows the subsequent uniform growth of a 1.77 eV WBG perovskite with superior optoelectronic quality. In addition, a postdeposition treatment with 2-thiopheneethylammonium chloride is employed to further suppress the bulk and interfacial recombination, boosting the V-OC of the WBG top cell to 1.29 V. Based on this, the first proof-of-concept four-terminal all-perovskite flexible TSC with a power conversion efficiency of 22.6% is presented. When integrating into two-terminal flexible tandems, 23.8% flexible all-perovskite TSCs with a superior V-OC of 2.1 V is achieved, which is on par with the V-OC reported on the 28% all-perovskite tandems grown on the rigid substrate. KW - all-perovskite tandems KW - flexible tandem solar cells KW - perovskite KW - V OC-deficit KW - wide-bandgap Y1 - 2022 U6 - https://doi.org/10.1002/aenm.202202438 SN - 1614-6832 SN - 1614-6840 VL - 12 IS - 45 PB - Wiley-VCH CY - Weinheim ER -