TY  - JOUR
A1  - Garcia, A. L.
A1  - Steiniger, J.
A1  - Reich, S. C.
A1  - Weickert, M. O.
A1  - Harsch, I.
A1  - Machowetz, A.
A1  - Mohlig, M.
A1  - Spranger, Joachim
A1  - Rudovich, N. N.
A1  - Meuser, F.
A1  - Doerfer, J.
A1  - Katz, N.
A1  - Speth, M.
A1  - Zunft, Hans-Joachim Franz
A1  - Pfeiffer, Andreas F. H.
A1  - Koebnick, Corinna
T1  - Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance
JF  - Hormone and metabolic research
N2  - The consumption of arabinoxylan, a soluble fibre fraction, has been shown to improve glycemic control in type 2 diabetic subjects. Soluble dietary fibre may modulate gastrointestinal or adipose tissue hormones regulating food intake. The present study investigated the effects of arabinoxylan consumption on serum glucose, insulin, lipids, leptin, adiponectin and resistin in subjects with impaired glucose tolerance. In a randomized, single-blind, controlled, crossover intervention trial, 11 adults consumed white bread rolls as either placebo or supplemented with 15g arabinoxylan for 6 weeks with a 6-week washout period. Fasting serum glucose, insulin, triglycerides, unesterified fatty acids, apolipoprotein A1 and B, adiponectin, resistin and leptin were assessed before and after intervention. Fasting serum glucose, serum triglycerides and apolipoprotein A-1 were significantly lower during arabinoxylan consumption compared to placebo (p = 0.029, p = 0.047; p = 0.029, respectively). No effects of arabinoxylan were observed for insulin, adiponectin, leptin and resistin as well as for apolipoprotein B, and unesterified fatty acids. In conclusion, the consumption of AX in subjects with impaired glucose tolerance improved fasting serum glucose, and triglycerides. However, this beneficial effect was not accompanied by changes in fasting adipokine concentrations.
KW  - dietary fibre
KW  - arabinoxylan
KW  - adiponectin
KW  - resistin
KW  - leptin
Y1  - 2006
U6  - https://doi.org/10.1055/s-2006-955089
SN  - 0018-5043
VL  - 38
IS  - 2
SP  - 761
EP  - 766
PB  - Thieme
CY  - Stuttgart
ER  -