TY  - JOUR
A1  - Goldmann, Daniela
A1  - Mahlstedt, S.
A1  - Janietz, Dietmar
A1  - Busch, P.
A1  - Schmidt, C.
A1  - Stracke, A.
A1  - Wendorff, Joachim Heinz
T1  - Mesomorphic donor-acceptor twin molecules with covalently linked sheet-like pentaalkyne and nitrofluorenone subunits
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Stracke, A.
A1  - Bayer, A.
A1  - Zimmermann, S.
A1  - Wendorff, Joachim Heinz
A1  - Wirges, Werner
A1  - Bauer-Gogonea, Simona
A1  - Bauer, Siegfried
A1  - Gerhard, Reimund
T1  - Relaxation behaviour of electrically induced polar orientation and of optically induced non-polar orientation in an azo-chromophore side group polymer
Y1  - 1999
SN  - 0022-3727
ER  - 
TY  - JOUR
A1  - Oda, Masao
A1  - Nothofer, Heinz-Georg
A1  - Lieser, G.
A1  - Scherf, Ullrich
A1  - Meskers, S. C. J.
A1  - Neher, Dieter
T1  - Circularly-polarized electroluminescence from liquid-crystalline chiral polyfluorenes
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Oda, Masao
A1  - Meskers, S. C. J.
A1  - Nothofer, Heinz-Georg
A1  - Scherf, Ullrich
A1  - Neher, Dieter
T1  - Chiroptical properties of chiral-substituted polyfluorenes
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Sianova, D.
A1  - Zen, Achmad
A1  - Nothofer, Heinz-Georg
A1  - Asawapirom, Udom
A1  - Scherf, Ullrich
A1  - Hagen, R.
A1  - Bieringer, Thomas
A1  - Kostromine, S.
A1  - Neher, Dieter
T1  - Photoaddressable alignment layers for fluorescent polymers in polarized electroluminescence devices
Y1  - 2002
ER  - 
TY  - GEN
A1  - Heinz, Wolfgang S.
T1  - Militär und Transition zur Demokratie in Lateinamerika : ein Rück- und Ausblick
T1  - Military and transition to democracy in Latin America
N2  - Since the beginning of the 1970s a lot of countries in Latin America has been starting the transition to democracy. The article analyses the role played by the military in this process, especially the effects of civildemocratic governments – sometimes failing in – gaining power over the military. It is described how and why the army occasionally kept their independence from the civil power and how this influenced the consolidation of democracy.
KW  - Lateinamerika
KW  - Militär
KW  - Übergang
KW  - zivil-militärische Beziehungen
KW  - Demokratie
KW  - Latin America
KW  - military
KW  - transition
KW  - civil-military relations
KW  - democracy
Y1  - 2005
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-48299
ER  - 
TY  - JOUR
A1  - Nettels, Daniel
A1  - Müller-Späth, Sonja
A1  - Küster, Frank
A1  - Hofmann, Hagen
A1  - Haenni, Domminik
A1  - Rüegger, Stefan
A1  - Reymond, Luc
A1  - Hoffmann, Armin S.
A1  - Kubelka, Jan
A1  - Heinz, Benjamin
A1  - Gast, Klaus
A1  - Best, Robert B.
A1  - Schuler, Benjamin
T1  - Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins
N2  - We used single-molecule FRET in combination with other biophysical methods and molecular simulations to investigate the effect of temperature on the dimensions of unfolded proteins. With singlemolecule FRET, this question can be addressed even under nearnative conditions, where most molecules are folded, allowing us to probe a wide range of denaturant concentrations and temperatures. We find a compaction of the unfolded state of a small cold shock protein with increasing temperature in both the presence and the absence of denaturant, with good agreement between the results from single-molecule FRET and dynamic light scattering. Although dissociation of denaturant from the polypeptide chain with increasing temperature accounts for part of the compaction, the results indicate an important role for additional temperaturedependent interactions within the unfolded chain. The observation of a collapse of a similar extent in the extremely hydrophilic, intrinsically disordered protein prothymosin suggests that the hydrophobic effect is not the sole source of the underlying interactions. Circular dichroism spectroscopy and replica exchange molecular dynamics simulations in explicit water show changes in secondary structure content with increasing temperature and suggest a contribution of intramolecular hydrogen bonding to unfolded state collapse.
Y1  - 2009
UR  - http://www.pnas.org/content/106/49/20740.full.pdf+html
SN  - 0027-8424
ER  - 
TY  - JOUR
A1  - Heinz, S.
A1  - Jung, I.
A1  - Stegmann, Christian
T1  - Systematic studies of the Richardson-Lucy deconvolution algorithm
 applied to VHE gamma data
JF  - ASTROPARTICLE PHYSICS
N2  - The Richardson-Lucy deconvolution algorithm was applied to astronomical images in the very high-energy regime with photon energies above 100 GeV. Through a systematic study with respect to source significance, background level and source morphology we were able to derive optimal deconvolution parameters. The results presented show that deconvolution makes it possible to study structural details well below the angular resolution of the very high-energy gamma-ray experiment. (C) 2012 Elsevier B.V. All rights reserved.
KW  - Very high energy gamma-ray astronomy
KW  - Deconvolution
Y1  - 2012
U6  - https://doi.org/10.1016/j.astropartphys.2012.05.013
SN  - 0927-6505
VL  - 36
IS  - 1
SP  - 146
EP  - 150
PB  - ELSEVIER SCIENCE BV
CY  - AMSTERDAM
ER  - 
TY  - JOUR
A1  - de Vera, Jean-Pierre Paul
A1  - Böttger, Ute
A1  - de la Torre Nötzel, Rosa
A1  - Sanchez, Francisco J.
A1  - Grunow, Dana
A1  - Schmitz, Nicole
A1  - Lange, Caroline
A1  - Hübers, Heinz-Wilhelm
A1  - Billi, Daniela
A1  - Baque, Mickael
A1  - Rettberg, Petra
A1  - Rabbow, Elke
A1  - Reitz, Günther
A1  - Berger, Thomas
A1  - Möller, Ralf
A1  - Bohmeier, Maria
A1  - Horneck, Gerda
A1  - Westall, Frances
A1  - Jänchen, Jochen
A1  - Fritz, Jörg
A1  - Meyer, Cornelia
A1  - Onofri, Silvano
A1  - Selbmann, Laura
A1  - Zucconi, Laura
A1  - Kozyrovska, Natalia
A1  - Leya, Thomas
A1  - Foing, Bernard
A1  - Demets, Rene
A1  - Cockell, Charles S.
A1  - Bryce, Casey
A1  - Wagner, Dirk
A1  - Serrano, Paloma
A1  - Edwards, Howell G. M.
A1  - Joshi, Jasmin Radha
A1  - Huwe, Björn
A1  - Ehrenfreund, Pascale
A1  - Elsaesser, Andreas
A1  - Ott, Sieglinde
A1  - Meessen, Joachim
A1  - Feyh, Nina
A1  - Szewzyk, Ulrich
A1  - Jaumann, Ralf
A1  - Spohn, Tilman
T1  - Supporting Mars exploration BIOMEX in Low Earth Orbit and further astrobiological studies on the Moon using Raman and PanCam technology
JF  - Planetary and space science
N2  - The Low Earth Orbit (LEO) experiment Biology and Mars Experiment (BIOMEX) is an interdisciplinary and international space research project selected by ESA. The experiment will be accommodated on the space exposure facility EXPOSE-R2 on the International Space Station (ISS) and is foreseen to be launched in 2013. The prime objective of BIOMEX is to measure to what extent biomolecules, such as pigments and cellular components, are resistant to and able to maintain their stability under space and Mars-like conditions. The results of BIOMEX will be relevant for space proven biosignature definition and for building a biosignature data base (e.g. the proposed creation of an international Raman library). The library will be highly relevant for future space missions such as the search for life on Mars. The secondary scientific objective is to analyze to what extent terrestrial extremophiles are able to survive in space and to determine which interactions between biological samples and selected minerals (including terrestrial, Moon- and Mars analogs) can be observed under space and Mars-like conditions. In this context, the Moon will be an additional platform for performing similar experiments with negligible magnetic shielding and higher solar and galactic irradiation compared to LEO. Using the Moon as an additional astrobiological exposure platform to complement ongoing astrobiological LEO investigations could thus enhance the chances of detecting organic traces of life on Mars. We present a lunar lander mission with two related objectives: a lunar lander equipped with Raman and PanCam instruments which can analyze the lunar surface and survey an astrobiological exposure platform. This dual use of testing mission technology together with geo- and astrobiological analyses will significantly increase the science return, and support the human preparation objectives. It will provide knowledge about the Moon's surface itself and, in addition, monitor the stability of life-markers, such as cells, cell components and pigments, in an extraterrestrial environment with much closer radiation properties to the surface of Mars. The combination of a Raman data base of these data together with data from LEO and space simulation experiments, will lead to further progress on the analysis and interpretation of data that we will obtain from future Moon and Mars exploration missions.
KW  - Moon
KW  - Mars
KW  - Low Earth Orbit
KW  - Astrobiology
KW  - Instrumentation
KW  - Spectroscopy
KW  - Biosignature
Y1  - 2012
U6  - https://doi.org/10.1016/j.pss.2012.06.010
SN  - 0032-0633
VL  - 74
IS  - 1
SP  - 103
EP  - 110
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - de Almeida, U. Barres
A1  - Becherini, Yvonne
A1  - Becker, J.
A1  - Behera, B.
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Buesching, I.
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Charbonnier, A.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Clapson, A. C.
A1  - Coignet, G.
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gallant, Y. A.
A1  - Gast, H.
A1  - Gerard, L.
A1  - Gerbig, D.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goret, P.
A1  - Goering, D.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hampf, D.
A1  - Hauser, M.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hoffmann, A.
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - de Jager, O. C.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Keogh, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, D.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Moderski, R.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nekrassov, D.
A1  - Nguyen, N.
A1  - Nicholas, B.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Arribas, M. Paz
A1  - Pedaletti, G.
A1  - Pelletier, G.
A1  - Petrucci, P. -O.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raue, M.
A1  - Rayner, S. M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Ruppel, J.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schoeck, F. M.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Vialle, J. P.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
A1  - Aleksic, J.
A1  - Antonelli, L. A.
A1  - Antoranz, P.
A1  - Backes, Michael
A1  - Barrio, J. A.
A1  - Bastieri, D.
A1  - Becerra Gonzalez, J.
A1  - Bednarek, W.
A1  - Berdyugin, A.
A1  - Berger, K.
A1  - Bernardini, E.
A1  - Biland, A.
A1  - Blanch Bigas, O.
A1  - Bock, R. K.
A1  - Boller, A.
A1  - Bonnoli, G.
A1  - Tridon, D. Borla
A1  - Braun, I.
A1  - Bretz, T.
A1  - Canellas, A.
A1  - Carmona, E.
A1  - Carosi, A.
A1  - Colin, P.
A1  - Colombo, E.
A1  - Contreras, J. L.
A1  - Cortina, J.
A1  - Cossio, L.
A1  - Covino, S.
A1  - Dazzi, F.
A1  - De Angelis, A.
A1  - De Cea del Pozo, E.
A1  - De Lotto, B.
A1  - Delgado Mendez, C.
A1  - Diago Ortega, A.
A1  - Doert, M.
A1  - Dominguez, A.
A1  - Prester, Dijana Dominis
A1  - Dorner, D.
A1  - Doro, M.
A1  - Elsaesser, D.
A1  - Ferenc, D.
A1  - Fonseca, M. V.
A1  - Font, L.
A1  - Fruck, C.
A1  - Garcia Lopez, R. J.
A1  - Garczarczyk, M.
A1  - Garrido, D.
A1  - Giavitto, G.
A1  - Godinovic, N.
A1  - Hadasch, D.
A1  - Haefner, D.
A1  - Herrero, A.
A1  - Hildebrand, D.
A1  - Hoehne-Moench, D.
A1  - Hose, J.
A1  - Hrupec, D.
A1  - Huber, B.
A1  - Jogler, T.
A1  - Klepser, S.
A1  - Kraehenbuehl, T.
A1  - Krause, J.
A1  - La Barbera, A.
A1  - Lelas, D.
A1  - Leonardo, E.
A1  - Lindfors, E.
A1  - Lombardi, S.
A1  - Lopez, M.
A1  - Lorenz, E.
A1  - Makariev, M.
A1  - Maneva, G.
A1  - Mankuzhiyil, N.
A1  - Mannheim, K.
A1  - Maraschi, L.
A1  - Mariotti, M.
A1  - Martinez, M.
A1  - Mazin, D.
A1  - Meucci, M.
A1  - Miranda, J. M.
A1  - Mirzoyan, R.
A1  - Miyamoto, H.
A1  - Moldon, J.
A1  - Moralejo, A.
A1  - Munar, P.
A1  - Nieto, D.
A1  - Nilsson, K.
A1  - Orito, R.
A1  - Oya, I.
A1  - Paneque, D.
A1  - Paoletti, R.
A1  - Pardo, S.
A1  - Paredes, J. M.
A1  - Partini, S.
A1  - Pasanen, M.
A1  - Pauss, F.
A1  - Perez-Torres, M. A.
A1  - Persic, M.
A1  - Peruzzo, L.
A1  - Pilia, M.
A1  - Pochon, J.
A1  - Prada, F.
A1  - Moroni, P. G. Prada
A1  - Prandini, E.
A1  - Puljak, I.
A1  - Reichardt, I.
A1  - Reinthal, R.
A1  - Rhode, W.
A1  - Ribo, M.
A1  - Rico, J.
A1  - Ruegamer, S.
A1  - Saggion, A.
A1  - Saito, K.
A1  - Saito, T. Y.
A1  - Salvati, M.
A1  - Satalecka, K.
A1  - Scalzotto, V.
A1  - Scapin, V.
A1  - Schultz, C.
A1  - Schweizer, T.
A1  - Shayduk, M.
A1  - Shore, S. N.
A1  - Sillanpaa, A.
A1  - Sitarek, J.
A1  - Sobczynska, D.
A1  - Spanier, F.
A1  - Spiro, S.
A1  - Stamerra, A.
A1  - Steinke, B.
A1  - Storz, J.
A1  - Strah, N.
A1  - Suric, T.
A1  - Takalo, L.
A1  - Takami, H.
A1  - Tavecchio, F.
A1  - Temnikov, P.
A1  - Terzic, T.
A1  - Tescaro, D.
A1  - Teshima, M.
A1  - Thom, M.
A1  - Tibolla, O.
A1  - Torres, D. F.
A1  - Treves, A.
A1  - Vankov, H.
A1  - Vogler, P.
A1  - Wagner, R. M.
A1  - Weitzel, Q.
A1  - Zabalza, V.
A1  - Zandanel, F.
A1  - Zanin, R.
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bouvier, A.
A1  - Bradbury, S. M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cannon, A.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Duke, C.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Finley, J. P.
A1  - Finnegan, G.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Godambe, S.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Huan, H.
A1  - Hui, C. M.
A1  - Kaaret, P.
A1  - Karlsson, N.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - LeBohec, S.
A1  - Maier, G.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nunez, P. D.
A1  - Ong, R. A.
A1  - Orr, M.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pichel, A.
A1  - Pohl, Martin
A1  - Prokoph, H.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Rose, H. J.
A1  - Ruppel, J.
A1  - Schroedter, M.
A1  - Sembroski, G. H.
A1  - Sentuerk, G. D.
A1  - Telezhinsky, Igor O.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Thibadeau, S.
A1  - Varlotta, A.
A1  - Vassiliev, V. V.
A1  - Vivier, M.
A1  - Wakely, S. P.
A1  - Weekes, T. C.
A1  - Williams, D. A.
A1  - Zitzer, B.
A1  - de Almeida, U. Barres
A1  - Cara, M.
A1  - Casadio, C.
A1  - Cheung, C. C.
A1  - McConville, W.
A1  - Davies, F.
A1  - Doi, A.
A1  - Giovannini, G.
A1  - Giroletti, M.
A1  - Hada, K.
A1  - Hardee, P.
A1  - Harris, D. E.
A1  - Junor, W.
A1  - Kino, M.
A1  - Lee, N. P.
A1  - Ly, C.
A1  - Madrid, J.
A1  - Massaro, F.
A1  - Mundell, C. G.
A1  - Nagai, H.
A1  - Perlman, E. S.
A1  - Steele, I. A.
A1  - Walker, R. C.
A1  - Wood, D. L.
T1  - The 2010 very high energy gamma-ray flare and 10 years ofmulti-wavelength oservations of M 87
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - The giant radio galaxy M 87 with its proximity (16 Mpc), famous jet, and very massive black hole ((3-6) x 10(9) M-circle dot) provides a unique opportunity to investigate the origin of very high energy (VHE; E > 100 GeV) gamma-ray emission generated in relativistic outflows and the surroundings of supermassive black holes. M 87 has been established as a VHE gamma-ray emitter since 2006. The VHE gamma-ray emission displays strong variability on timescales as short as a day. In this paper, results from a joint VHE monitoring campaign on M 87 by the MAGIC and VERITAS instruments in 2010 are reported. During the campaign, a flare at VHE was detected triggering further observations at VHE (H.E.S.S.), X-rays (Chandra), and radio (43 GHz Very Long Baseline Array, VLBA). The excellent sampling of the VHE gamma-ray light curve enables one to derive a precise temporal characterization of the flare: the single, isolated flare is well described by a two-sided exponential function with significantly different flux rise and decay times of tau(rise)(d) = (1.69 +/- 0.30) days and tau(decay)(d) = (0.611 +/- 0.080) days, respectively. While the overall variability pattern of the 2010 flare appears somewhat different from that of previous VHE flares in 2005 and 2008, they share very similar timescales (similar to day), peak fluxes (Phi(>0.35 TeV) similar or equal to (1-3) x 10(-11) photons cm(-2) s(-1)), and VHE spectra. VLBA radio observations of 43 GHz of the inner jet regions indicate no enhanced flux in 2010 in contrast to observations in 2008, where an increase of the radio flux of the innermost core regions coincided with a VHE flare. On the other hand, Chandra X-ray observations taken similar to 3 days after the peak of the VHE gamma-ray emission reveal an enhanced flux from the core (flux increased by factor similar to 2; variability timescale <2 days). The long-term (2001-2010) multi-wavelength (MWL) light curve of M 87, spanning from radio to VHE and including data from Hubble Space Telescope, Liverpool Telescope, Very Large Array, and European VLBI Network, is used to further investigate the origin of the VHE gamma-ray emission. No unique, common MWL signature of the three VHE flares has been identified. In the outer kiloparsec jet region, in particular in HST-1, no enhanced MWL activity was detected in 2008 and 2010, disfavoring it as the origin of the VHE flares during these years. Shortly after two of the three flares (2008 and 2010), the X-ray core was observed to be at a higher flux level than its characteristic range (determined from more than 60 monitoring observations: 2002-2009). In 2005, the strong flux dominance of HST-1 could have suppressed the detection of such a feature. Published models for VHE gamma-ray emission from M 87 are reviewed in the light of the new data.
KW  - galaxies: active
KW  - galaxies: individual (M 87)
KW  - galaxies: jets
KW  - galaxies: nuclei
KW  - gamma rays: galaxies
KW  - radiation mechanisms: non-thermal
Y1  - 2012
U6  - https://doi.org/10.1088/0004-637X/746/2/151
SN  - 0004-637X
VL  - 746
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O&rsquo
A1  - C., 
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M-H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C-C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - de Ona Wilhelmi, E.
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J-P
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H-S
T1  - Search for very-high-energy gamma-ray emission from Galactic globular
 clusters with HESS
JF  - ASTRONOMY & ASTROPHYSICS
N2  - Context. Globular clusters (GCs) are established emitters of high-energy (HE, 100 MeV < E < 100 GeV) gamma-ray radiation which could originate from the cumulative emission of the numerous millisecond pulsars (msPSRs) in the clusters&rsquo; cores or from inverse Compton (IC) scattering of relativistic leptons accelerated in the GC environment. These stellar clusters could also constitute a new class of sources in the very-high-energy (VHE, E > 100 GeV) gamma-ray regime, judging from the recent detection of a signal from the direction of Terzan 5 with the H.E.S.S. telescope array. Aims. To search for VHE gamma-ray sources associated with other GCs, and to put constraints on leptonic emission models, we systematically analyzed the observations towards 15 GCs taken with the H. E. S. S. array of imaging atmospheric Cherenkov telescopes. Methods. We searched for point-like and extended VHE gamma-ray emission from each GC in our sample and also performed a stacking analysis combining the data from all GCs to investigate the hypothesis of a population of faint emitters. Assuming IC emission as the origin of the VHE gamma-ray signal from the direction of Terzan 5, we calculated the expected gamma-ray flux from each of the 15 GCs, based on their number of millisecond pulsars, their optical brightness and the energy density of background photon fields. Results. We did not detect significant VHE gamma-ray emission from any of the 15 GCs in either of the two analyses. Given the uncertainties related to the parameter determinations, the obtained flux upper limits allow to rule out the simple IC/msPSR scaling model for NGC6388 and NGC7078. The upper limits derived from the stacking analyses are factors between 2 and 50 below the flux predicted by the simple leptonic scaling model, depending on the assumed source extent and the dominant target photon fields. Therefore, Terzan 5 still remains exceptional among all GCs, as the VHE gamma-ray emission either arises from extra-ordinarily efficient leptonic processes, or from a recent catastrophic event, or is even unrelated to the GC itself.
KW  - globular clusters: general
KW  - radiation mechanisms: non-thermal
KW  - pulsars: general
KW  - gamma rays: general
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201220719
SN  - 0004-6361
VL  - 551
PB  - EDP SCIENCES S A
CY  - LES ULIS CEDEX A
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Behera, B.
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foester, A.
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goeing, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Hauser, M.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, Markus
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. S.
T1  - HESS discovery of VHE gamma-rays from the quasar PKS 1510-089
JF  - Astronomy and astrophysics : an international weekly journal
N2  - The quasar PKS 1510-089 (z = 0.361) was observed with the H.E.S.S. array of imaging atmospheric Cherenkov telescopes during high states in the optical and GeV bands, to search for very high energy (VHE, defined as E >= 0.1 TeV) emission. VHE gamma-rays were detected with a statistical significance of 9.2 standard deviations in 15.8 h of H. E. S. S. data taken during March and April 2009. A VHE integral flux of I(0.15 TeV < E < 1.0TeV) = (1.0 +/- 0.2(stat) +/- 0.2(sys)) x 10(-11) cm(-2) s(-1) is measured. The best-fit power law to the VHE data has a photon index of G = 5.4 +/- 0.7(stat) +/- 0.3(sys). The GeV and optical light curves show pronounced variability during the period of H.E.S.S. observations. However, there is insufficient evidence to claim statistically significant variability in the VHE data. Because of its relatively high redshift, the VHE flux from PKS 1510-089 should suffer considerable attenuation in the intergalactic space due to the extragalactic background light (EBL). Hence, the measured gamma-ray spectrum is used to derive upper limits on the opacity due to EBL, which are found to be comparable with the previously derived limits from relatively-nearby BL Lac objects. Unlike typical VHE-detected blazars where the broadband spectrum is dominated by nonthermal radiation at all wavelengths, the quasar PKS 1510-089 has a bright thermal component in the optical to UV frequency band. Among all VHE detected blazars, PKS 1510-089 has the most luminous broad line region. The detection of VHE emission from this quasar indicates a low level of gamma - gamma absorption on the internal optical to UV photon field.
KW  - gamma rays: galaxies
KW  - quasars: individual: PKS 1510-089
KW  - infrared: diffuse background
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201321135
SN  - 0004-6361
VL  - 554
IS  - 6
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fussling, Matthias
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M. -H.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nekrassov, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Awilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
T1  - Search for Photon-Linelike Signatures from Dark Matter Annihilations with H.E.S.S.
JF  - Physical review letters
N2  - Gamma-ray line signatures can be expected in the very-high-energy (E-gamma > 100 GeV) domain due to self-annihilation or decay of dark matter (DM) particles in space. Such a signal would be readily distinguishable from astrophysical gamma-ray sources that in most cases produce continuous spectra that span over several orders of magnitude in energy. Using data collected with the H. E. S. S. gamma-ray instrument, upper limits on linelike emission are obtained in the energy range between similar to 500 GeV and similar to 25 TeV for the central part of the Milky Way halo and for extragalactic observations, complementing recent limits obtained with the Fermi-LAT instrument at lower energies. No statistically significant signal could be found. For monochromatic gamma-ray line emission, flux limits of (2 x 10(-7)-2 x 10(-5)) m(-2)s(-1)sr(-1) and (1 x 10(-8)- 2 x 10(-6)) m(-2)s(-1)sr(-1) are obtained for the central part of the Milky Way halo and extragalactic observations, respectively. For a DM particle mass of 1 TeV, limits on the velocity- averaged DM annihilation cross section <sigma upsilon >(chi chi ->gamma gamma) reach similar to 10(-27)cm(3)s(-1), based on the Einasto parametrization of the Galactic DM halo density profile. DOI: 10.1103/PhysRevLett.110.041301
Y1  - 2013
U6  - https://doi.org/10.1103/PhysRevLett.110.041301
SN  - 0031-9007
VL  - 110
IS  - 4
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Behera, B.
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O&rsquo
A1  - C., 
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fussling, Matthias
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Kolitzus, D.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
A1  - Pelat, D.
T1  - Discovery of TeV gamma-ray emission from PKS 0447-439 and derivation of
 an upper limit on its redshift
JF  - ASTRONOMY & ASTROPHYSICS
N2  - Very high-energy gamma-ray emission from PKS 0447-439 was detected with the H. E. S. S. Cherenkov telescope array in December 2009. This blazar is one of the brightest extragalactic objects in the Fermi bright source list and has a hard spectrum in the MeV to GeV range. In the TeV range, a photon index of 3.89 +/- 0.37 (stat) +/- 0.22 (sys) and a flux normalisation at 1 TeV, phi(1) (TeV) = (3.5 +/- 1.1(stat) +/- 0.9(sys)) x 10(-13) cm(-2) s(-1) TeV-1 were found. The detection with H. E. S. S. triggered observations in the X-ray band with the Swift and RXTE telescopes. Simultaneous UV and optical data from Swift UVOT and data from the optical telescopes ATOM and ROTSE are also available. The spectrum and light curve measured with H. E. S. S. are presented and compared to the multi-wavelength data at lower energies. A rapid flare is seen in the Swift XRT and RXTE data, together with a flux variation in the UV band, at a time scale of the order of one day. A firm upper limit of z < 0.59 on the redshift of PKS 0447-439 is derived from the combined Fermi-LAT and H. E. S. S. data, given the assumptions that there is no upturn in the intrinsic spectrum above the Fermi-LAT energy range and that absorption on the extragalactic background light (EBL) is not weaker than the lower limit provided by current models. The spectral energy distribution is well described by a simple one-zone synchrotron self-Compton scenario, if the redshift of the source is less than z less than or similar to 0.4.
KW  - galaxies: active
KW  - BL Lacertae objects: individual: PKS 0447-439
KW  - radiation mechanisms: non-thermal
KW  - gamma rays: galaxies
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201321108
SN  - 0004-6361
VL  - 552
IS  - 4
PB  - EDP SCIENCES S A
CY  - LES ULIS CEDEX A
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, Markus
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Kolitzus, D.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Oakes, L.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
T1  - HESS observations of the binary system PSR B1259-63/LS 2883 around the 2010/2011 periastron passage
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Aims. We present very high energy (VHE; E > 100 GeV) data from the gamma-ray binary system PSR B1259-63/LS 2883 taken around its periastron passage on 15th of December 2010 with the High Energy Stereoscopic System (H. E. S. S.) of Cherenkov Telescopes. We aim to search for a possible TeV counterpart of the GeV flare detected by the Fermi LAT. In addition, we aim to study the current periastron passage in the context of previous observations taken at similar orbital phases, testing the repetitive behaviour of the source.
 Methods. Observations at VHEs were conducted with H.E.S.S. from 9th to 16th of January 2011. The total dataset amounts to similar to 6 h of observing time. The data taken around the 2004 periastron passage were also re-analysed with the current analysis techniques in order to extend the energy spectrum above 3 TeV to fully compare observation results from 2004 and 2011.
 Results. The source is detected in the 2011 data at a significance level of 11.5 sigma revealing an averaged integral flux above 1 TeV of (1.01 +/- 0.18(stat) +/- 0.20(sys)) x 10(-12) cm(-2) s(-1). The differential energy spectrum follows a power-law shape with a spectral index Gamma = 2.92 +/- 0.30(stat) +/- 0.20(sys) and a flux normalisation at 1 TeV of N-0 = (1.95 +/- 0.32(stat) +/- 0.39(sys)) x 10(-12) TeV-1 cm(-2) s(-1). The measured light curve does not show any evidence for variability of the source on the daily scale. The re-analysis of the 2004 data yields results compatible with the published ones. The differential energy spectrum measured up to similar to 10 TeV is consistent with a power law with a spectral index Gamma = 2.81 +/- 0.10(stat) +/- 0.20(sys) and a flux normalisation at 1 TeV of N-0 = (1.29 +/- 0.08(stat) +/- 0.26(sys)) x 10(-12) TeV-1 cm(-2) s(-1).
 Conclusions. The measured integral flux and the spectral shape of the 2011 data are compatible with the results obtained around previous periastron passages. The absence of variability in the H.E.S.S. data indicates that the GeV flare observed by Fermi LAT in the time period covered also by H.E.S.S. observations originates in a different physical scenario than the TeV emission. Moreover, the comparison of the new results to the results from the 2004 observations made at a similar orbital phase provides a stronger evidence of the repetitive behaviour of the source.
KW  - gamma rays: general
KW  - pulsars: individual: PSR B1259-63
KW  - X-rays: binaries
KW  - stars: individual: LS 2883
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201220612
SN  - 0004-6361
VL  - 551
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - CHAP
A1  - Völler, Heinz
A1  - Salzwedel, Annett
A1  - Reibis, Rona Katharina
A1  - Kaminski, S.
A1  - Buhlert, Hermann
A1  - Eichler, Sarah
A1  - Wegscheider, Karl
T1  - Age and fitness level are strongest limitations of exercise capacity during inpatient cardiac rehabilitation
T2  - European heart journal
Y1  - 2014
SN  - 0195-668X
SN  - 1522-9645
VL  - 35
SP  - 899
EP  - 899
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Roehrig, B.
A1  - Nosper, M.
A1  - Linck-Eleftheriadis, S.
A1  - Strandt, G.
A1  - Salzwedel, Annett
A1  - Völler, Heinz
T1  - Method of the assessment of patients Outcome in cardiac rehabilitation by means of quality indicators - a description of the method
JF  - Die Rehabilitation : Zeitschrift für Praxis und Forschung in der Rehabilitation
N2  - Introduction: Cardiac rehabilitation is designed for patients suffering from cardiovascular diseases or functional disabilities. The aim of a cardiac rehabilitation is to improve overall physical health, psychological well-being, physical function, the ability to participate in social life and help patients to change their habits. Regarding the heterogeneity of these aims measuring of the effect of cardiac rehabilitation is still a challenge. This study recommends a concept to assess the effects of cardiac rehabilitation regarding the individual change of relevant quality indicators.
 Methods: With EVA-Reha; cardiac rehabilitation the Medical Advisory Service of Statutory Health Insurance Funds in Rhineland-Palatinate, Alzey (MDK Rheinland-Pfalz) developed a software to collect data set including sociodemographic and diagnostic data and also the results of specific assessments. The project was funded by the Techniker Krankenkasse, Hamburg, and supported by participating rehabilitation centers. From 01. July 2010 to 30. June 2011 1309 patients (age 71.5 years, 76.1% men) from 13 rehabilitation centers were consecutively enrolled. 13 quality indicators in 3 scales were developed for evaluation of cardiac rehabilitation: 1) cardiovascular risk factors (blood pressure, LDL cholesterol, triglycerides), 2) exercise capacity (resting heart rate, maximal exercise capacity, maximal walking distance, heart failure [NYHA classification], and angina pectoris [CCS classification]) and 3) subjective health (IRES-24: pain, somatic health, psychological wellbeing and depression as well as anxiety on the HADS). The study was prospective; data of patients were assessed at entry and discharge of rehabilitation. To measure the success of rehabilitation each parameter was graded in severity classes at entry and discharge. For each of the 13 quality indicators changes of severity class were rated in a rating matrix. For indicators without a requirement for medical care neither at entry nor at discharge no rating was performed.
 Results: The grading into severity classes as well as the minimal important differences were given for the 13 quality indicators. The result of rehabilitation can be demonstrated in suitable form by means of rating of the 13 quality indicators according to a clinical population. The rating model differs well between clinically changed and unchanged patients for the quality indicators.
 Conclusion: The result of cardiac rehabilitation can be assessed with 13 quality indicators measured at entry and discharge of the rehabilitation program. If a change into a more favorable category at the end of rehabilitation could be achieved it was counted as a success. The 13 quality indicators can be used to assess the individual result as well as the result of a population - e.g. all patients of a clinic in a specific time period. In addition, the assessment and rating of relevant quality indicators can be used for comparisons of rehabilitation centers.
KW  - cardiac rehabilitation
KW  - quality indicator
KW  - outcome
KW  - success
KW  - quality management
Y1  - 2014
U6  - https://doi.org/10.1055/s-0033-1341457
SN  - 0034-3536
SN  - 1439-1309
VL  - 53
IS  - 1
SP  - 31
EP  - 37
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Garbusow, Maria
A1  - Schad, Daniel
A1  - Sommer, Christian
A1  - Juenger, Elisabeth
A1  - Sebold, Miriam
A1  - Friedel, Eva
A1  - Wendt, Jean
A1  - Kathmann, Norbert
A1  - Schlagenhauf, Florian
A1  - Zimmermann, Ulrich S.
A1  - Heinz, Andreas
A1  - Huys, Quentin J. M.
A1  - Rapp, Michael A.
T1  - Pavlovian-to-instrumental transfer in alcohol dependence: a pilot study
JF  - Neuropsychobiology : international journal of experimental and clinical research in biological psychiatry, pharmacopsychiatry, Biological Psychology/Pharmacopsychology and Pharmacoelectroencephalography
N2  - Background: Pavlovian processes are thought to play an important role in the development, maintenance and relapse of alcohol dependence, possibly by influencing and usurping ongoing thought and behavior. The influence of pavlovian stimuli on ongoing behavior is paradigmatically measured by pavlovian-to-instrumental transfer (PIT) tasks. These involve multiple stages and are complex. Whether increased PIT is involved in human alcohol dependence is uncertain. We therefore aimed to establish and validate a modified PIT paradigm that would be robust, consistent and tolerated by healthy controls as well as by patients suffering from alcohol dependence, and to explore whether alcohol dependence is associated with enhanced PIT. Methods: Thirty-two recently detoxified alcohol-dependent patients and 32 age- and gender-matched healthy controls performed a PIT task with instrumental go/no-go approach behaviors. The task involved both pavlovian stimuli associated with monetary rewards and losses, and images of drinks. Results: Both patients and healthy controls showed a robust and temporally stable PIT effect. Strengths of PIT effects to drug-related and monetary conditioned stimuli were highly correlated. Patients more frequently showed a PIT effect, and the effect was stronger in response to aversively conditioned CSs (conditioned suppression), but there was no group difference in response to appetitive CSs. Conclusion: The implementation of PIT has favorably robust properties in chronic alcohol-dependent patients and in healthy controls. It shows internal consistency between monetary and drug-related cues. The findings support an association of alcohol dependence with an increased propensity towards PIT.
KW  - Pavlovian-to-instrumental transfer
KW  - Alcohol dependence
KW  - Human
Y1  - 2014
U6  - https://doi.org/10.1159/000363507
SN  - 0302-282X
SN  - 1423-0224
VL  - 70
IS  - 2
SP  - 111
EP  - 121
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Schad, Daniel
A1  - Juenger, Elisabeth
A1  - Sebold, Miriam
A1  - Garbusow, Maria
A1  - Bernhardt, Nadine
A1  - Javadi, Amir-Homayoun
A1  - Zimmermann, Ulrich S.
A1  - Smolka, Michael N.
A1  - Heinz, Andreas
A1  - Rapp, Michael A.
A1  - Huys, Quentin J. M.
T1  - Processing speed enhances model-based over model-free reinforcement learning in the presence of high working memory functioning
JF  - Frontiers in psychology
N2  - Theories of decision-making and its neural substrates have long assumed the existence of two distinct and competing valuation systems, variously described as goal-directed vs. habitual, or, more recently and based on statistical arguments, as model-free vs. model-based reinforcement-learning. Though both have been shown to control choices, the cognitive abilities associated with these systems are under ongoing investigation. Here we examine the link to cognitive abilities, and find that individual differences in processing speed covary with a shift from model-free to model-based choice control in the presence of above-average working memory function. This suggests shared cognitive and neural processes; provides a bridge between literatures on intelligence and valuation; and may guide the development of process models of different valuation components. Furthermore, it provides a rationale for individual differences in the tendency to deploy valuation systems, which may be important for understanding the manifold neuropsychiatric diseases associated with malfunctions of valuation.
KW  - decision-making
KW  - reward
KW  - cognitive abilities
KW  - model-based and model-free learning
KW  - fluid intelligence
KW  - habitual and goal-directed system
Y1  - 2014
U6  - https://doi.org/10.3389/fpsyg.2014.01450
SN  - 1664-1078
VL  - 5
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - CHAP
A1  - Schad, Daniel
A1  - Juenger, Elisabeth
A1  - Sebold, Miriam
A1  - Garbusow, Maria
A1  - Bernhart, Nadine
A1  - Javadi, Amir Homayoun
A1  - Zimmermann, Ulrich S.
A1  - Smolka, Michael N.
A1  - Heinz, Andreas
A1  - Rapp, Michael A.
A1  - Huys, Quentin J. M.
T1  - Smart goals, slow habits? Individual differences in processing speed and working memory capacity moderate the balance between habitual and goal-directed choice behavior
T2  - Cognitive processing : international quarterly of cognitive science
Y1  - 2014
SN  - 1612-4782
SN  - 1612-4790
VL  - 15
IS  - 1
SP  - S62
EP  - S62
PB  - Springer
CY  - Heidelberg
ER  -