TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - de Almeida, U. Barres
A1  - Becherini, Yvonne
A1  - Becker, J.
A1  - Behera, B.
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Buesching, I.
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Charbonnier, A.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Clapson, A. C.
A1  - Coignet, G.
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gallant, Y. A.
A1  - Gast, H.
A1  - Gerard, L.
A1  - Gerbig, D.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goret, P.
A1  - Goering, D.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hampf, D.
A1  - Hauser, M.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hoffmann, A.
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - de Jager, O. C.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Keogh, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, D.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Moderski, R.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nekrassov, D.
A1  - Nguyen, N.
A1  - Nicholas, B.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Arribas, M. Paz
A1  - Pedaletti, G.
A1  - Pelletier, G.
A1  - Petrucci, P. -O.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raue, M.
A1  - Rayner, S. M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Ruppel, J.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Schlickeiser, R.
A1  - Schoeck, F. M.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Vialle, J. P.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
A1  - Aleksic, J.
A1  - Antonelli, L. A.
A1  - Antoranz, P.
A1  - Backes, Michael
A1  - Barrio, J. A.
A1  - Bastieri, D.
A1  - Becerra Gonzalez, J.
A1  - Bednarek, W.
A1  - Berdyugin, A.
A1  - Berger, K.
A1  - Bernardini, E.
A1  - Biland, A.
A1  - Blanch Bigas, O.
A1  - Bock, R. K.
A1  - Boller, A.
A1  - Bonnoli, G.
A1  - Tridon, D. Borla
A1  - Braun, I.
A1  - Bretz, T.
A1  - Canellas, A.
A1  - Carmona, E.
A1  - Carosi, A.
A1  - Colin, P.
A1  - Colombo, E.
A1  - Contreras, J. L.
A1  - Cortina, J.
A1  - Cossio, L.
A1  - Covino, S.
A1  - Dazzi, F.
A1  - De Angelis, A.
A1  - De Cea del Pozo, E.
A1  - De Lotto, B.
A1  - Delgado Mendez, C.
A1  - Diago Ortega, A.
A1  - Doert, M.
A1  - Dominguez, A.
A1  - Prester, Dijana Dominis
A1  - Dorner, D.
A1  - Doro, M.
A1  - Elsaesser, D.
A1  - Ferenc, D.
A1  - Fonseca, M. V.
A1  - Font, L.
A1  - Fruck, C.
A1  - Garcia Lopez, R. J.
A1  - Garczarczyk, M.
A1  - Garrido, D.
A1  - Giavitto, G.
A1  - Godinovic, N.
A1  - Hadasch, D.
A1  - Haefner, D.
A1  - Herrero, A.
A1  - Hildebrand, D.
A1  - Hoehne-Moench, D.
A1  - Hose, J.
A1  - Hrupec, D.
A1  - Huber, B.
A1  - Jogler, T.
A1  - Klepser, S.
A1  - Kraehenbuehl, T.
A1  - Krause, J.
A1  - La Barbera, A.
A1  - Lelas, D.
A1  - Leonardo, E.
A1  - Lindfors, E.
A1  - Lombardi, S.
A1  - Lopez, M.
A1  - Lorenz, E.
A1  - Makariev, M.
A1  - Maneva, G.
A1  - Mankuzhiyil, N.
A1  - Mannheim, K.
A1  - Maraschi, L.
A1  - Mariotti, M.
A1  - Martinez, M.
A1  - Mazin, D.
A1  - Meucci, M.
A1  - Miranda, J. M.
A1  - Mirzoyan, R.
A1  - Miyamoto, H.
A1  - Moldon, J.
A1  - Moralejo, A.
A1  - Munar, P.
A1  - Nieto, D.
A1  - Nilsson, K.
A1  - Orito, R.
A1  - Oya, I.
A1  - Paneque, D.
A1  - Paoletti, R.
A1  - Pardo, S.
A1  - Paredes, J. M.
A1  - Partini, S.
A1  - Pasanen, M.
A1  - Pauss, F.
A1  - Perez-Torres, M. A.
A1  - Persic, M.
A1  - Peruzzo, L.
A1  - Pilia, M.
A1  - Pochon, J.
A1  - Prada, F.
A1  - Moroni, P. G. Prada
A1  - Prandini, E.
A1  - Puljak, I.
A1  - Reichardt, I.
A1  - Reinthal, R.
A1  - Rhode, W.
A1  - Ribo, M.
A1  - Rico, J.
A1  - Ruegamer, S.
A1  - Saggion, A.
A1  - Saito, K.
A1  - Saito, T. Y.
A1  - Salvati, M.
A1  - Satalecka, K.
A1  - Scalzotto, V.
A1  - Scapin, V.
A1  - Schultz, C.
A1  - Schweizer, T.
A1  - Shayduk, M.
A1  - Shore, S. N.
A1  - Sillanpaa, A.
A1  - Sitarek, J.
A1  - Sobczynska, D.
A1  - Spanier, F.
A1  - Spiro, S.
A1  - Stamerra, A.
A1  - Steinke, B.
A1  - Storz, J.
A1  - Strah, N.
A1  - Suric, T.
A1  - Takalo, L.
A1  - Takami, H.
A1  - Tavecchio, F.
A1  - Temnikov, P.
A1  - Terzic, T.
A1  - Tescaro, D.
A1  - Teshima, M.
A1  - Thom, M.
A1  - Tibolla, O.
A1  - Torres, D. F.
A1  - Treves, A.
A1  - Vankov, H.
A1  - Vogler, P.
A1  - Wagner, R. M.
A1  - Weitzel, Q.
A1  - Zabalza, V.
A1  - Zandanel, F.
A1  - Zanin, R.
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bouvier, A.
A1  - Bradbury, S. M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Byrum, K.
A1  - Cannon, A.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Duke, C.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Finley, J. P.
A1  - Finnegan, G.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Godambe, S.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Huan, H.
A1  - Hui, C. M.
A1  - Kaaret, P.
A1  - Karlsson, N.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - LeBohec, S.
A1  - Maier, G.
A1  - McArthur, S.
A1  - McCann, A.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nunez, P. D.
A1  - Ong, R. A.
A1  - Orr, M.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pichel, A.
A1  - Pohl, Martin
A1  - Prokoph, H.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Rose, H. J.
A1  - Ruppel, J.
A1  - Schroedter, M.
A1  - Sembroski, G. H.
A1  - Sentuerk, G. D.
A1  - Telezhinsky, Igor O.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Thibadeau, S.
A1  - Varlotta, A.
A1  - Vassiliev, V. V.
A1  - Vivier, M.
A1  - Wakely, S. P.
A1  - Weekes, T. C.
A1  - Williams, D. A.
A1  - Zitzer, B.
A1  - de Almeida, U. Barres
A1  - Cara, M.
A1  - Casadio, C.
A1  - Cheung, C. C.
A1  - McConville, W.
A1  - Davies, F.
A1  - Doi, A.
A1  - Giovannini, G.
A1  - Giroletti, M.
A1  - Hada, K.
A1  - Hardee, P.
A1  - Harris, D. E.
A1  - Junor, W.
A1  - Kino, M.
A1  - Lee, N. P.
A1  - Ly, C.
A1  - Madrid, J.
A1  - Massaro, F.
A1  - Mundell, C. G.
A1  - Nagai, H.
A1  - Perlman, E. S.
A1  - Steele, I. A.
A1  - Walker, R. C.
A1  - Wood, D. L.
T1  - The 2010 very high energy gamma-ray flare and 10 years ofmulti-wavelength oservations of M 87
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - The giant radio galaxy M 87 with its proximity (16 Mpc), famous jet, and very massive black hole ((3-6) x 10(9) M-circle dot) provides a unique opportunity to investigate the origin of very high energy (VHE; E > 100 GeV) gamma-ray emission generated in relativistic outflows and the surroundings of supermassive black holes. M 87 has been established as a VHE gamma-ray emitter since 2006. The VHE gamma-ray emission displays strong variability on timescales as short as a day. In this paper, results from a joint VHE monitoring campaign on M 87 by the MAGIC and VERITAS instruments in 2010 are reported. During the campaign, a flare at VHE was detected triggering further observations at VHE (H.E.S.S.), X-rays (Chandra), and radio (43 GHz Very Long Baseline Array, VLBA). The excellent sampling of the VHE gamma-ray light curve enables one to derive a precise temporal characterization of the flare: the single, isolated flare is well described by a two-sided exponential function with significantly different flux rise and decay times of tau(rise)(d) = (1.69 +/- 0.30) days and tau(decay)(d) = (0.611 +/- 0.080) days, respectively. While the overall variability pattern of the 2010 flare appears somewhat different from that of previous VHE flares in 2005 and 2008, they share very similar timescales (similar to day), peak fluxes (Phi(>0.35 TeV) similar or equal to (1-3) x 10(-11) photons cm(-2) s(-1)), and VHE spectra. VLBA radio observations of 43 GHz of the inner jet regions indicate no enhanced flux in 2010 in contrast to observations in 2008, where an increase of the radio flux of the innermost core regions coincided with a VHE flare. On the other hand, Chandra X-ray observations taken similar to 3 days after the peak of the VHE gamma-ray emission reveal an enhanced flux from the core (flux increased by factor similar to 2; variability timescale <2 days). The long-term (2001-2010) multi-wavelength (MWL) light curve of M 87, spanning from radio to VHE and including data from Hubble Space Telescope, Liverpool Telescope, Very Large Array, and European VLBI Network, is used to further investigate the origin of the VHE gamma-ray emission. No unique, common MWL signature of the three VHE flares has been identified. In the outer kiloparsec jet region, in particular in HST-1, no enhanced MWL activity was detected in 2008 and 2010, disfavoring it as the origin of the VHE flares during these years. Shortly after two of the three flares (2008 and 2010), the X-ray core was observed to be at a higher flux level than its characteristic range (determined from more than 60 monitoring observations: 2002-2009). In 2005, the strong flux dominance of HST-1 could have suppressed the detection of such a feature. Published models for VHE gamma-ray emission from M 87 are reviewed in the light of the new data.
KW  - galaxies: active
KW  - galaxies: individual (M 87)
KW  - galaxies: jets
KW  - galaxies: nuclei
KW  - gamma rays: galaxies
KW  - radiation mechanisms: non-thermal
Y1  - 2012
U6  - https://doi.org/10.1088/0004-637X/746/2/151
SN  - 0004-637X
VL  - 746
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Behera, B.
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foester, A.
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goeing, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Hauser, M.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, Markus
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. S.
T1  - HESS discovery of VHE gamma-rays from the quasar PKS 1510-089
JF  - Astronomy and astrophysics : an international weekly journal
N2  - The quasar PKS 1510-089 (z = 0.361) was observed with the H.E.S.S. array of imaging atmospheric Cherenkov telescopes during high states in the optical and GeV bands, to search for very high energy (VHE, defined as E >= 0.1 TeV) emission. VHE gamma-rays were detected with a statistical significance of 9.2 standard deviations in 15.8 h of H. E. S. S. data taken during March and April 2009. A VHE integral flux of I(0.15 TeV < E < 1.0TeV) = (1.0 +/- 0.2(stat) +/- 0.2(sys)) x 10(-11) cm(-2) s(-1) is measured. The best-fit power law to the VHE data has a photon index of G = 5.4 +/- 0.7(stat) +/- 0.3(sys). The GeV and optical light curves show pronounced variability during the period of H.E.S.S. observations. However, there is insufficient evidence to claim statistically significant variability in the VHE data. Because of its relatively high redshift, the VHE flux from PKS 1510-089 should suffer considerable attenuation in the intergalactic space due to the extragalactic background light (EBL). Hence, the measured gamma-ray spectrum is used to derive upper limits on the opacity due to EBL, which are found to be comparable with the previously derived limits from relatively-nearby BL Lac objects. Unlike typical VHE-detected blazars where the broadband spectrum is dominated by nonthermal radiation at all wavelengths, the quasar PKS 1510-089 has a bright thermal component in the optical to UV frequency band. Among all VHE detected blazars, PKS 1510-089 has the most luminous broad line region. The detection of VHE emission from this quasar indicates a low level of gamma - gamma absorption on the internal optical to UV photon field.
KW  - gamma rays: galaxies
KW  - quasars: individual: PKS 1510-089
KW  - infrared: diffuse background
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201321135
SN  - 0004-6361
VL  - 554
IS  - 6
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O&rsquo
A1  - C., 
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M-H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C-C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - de Ona Wilhelmi, E.
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J-P
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H-S
T1  - Search for very-high-energy gamma-ray emission from Galactic globular
 clusters with HESS
JF  - ASTRONOMY & ASTROPHYSICS
N2  - Context. Globular clusters (GCs) are established emitters of high-energy (HE, 100 MeV < E < 100 GeV) gamma-ray radiation which could originate from the cumulative emission of the numerous millisecond pulsars (msPSRs) in the clusters&rsquo; cores or from inverse Compton (IC) scattering of relativistic leptons accelerated in the GC environment. These stellar clusters could also constitute a new class of sources in the very-high-energy (VHE, E > 100 GeV) gamma-ray regime, judging from the recent detection of a signal from the direction of Terzan 5 with the H.E.S.S. telescope array. Aims. To search for VHE gamma-ray sources associated with other GCs, and to put constraints on leptonic emission models, we systematically analyzed the observations towards 15 GCs taken with the H. E. S. S. array of imaging atmospheric Cherenkov telescopes. Methods. We searched for point-like and extended VHE gamma-ray emission from each GC in our sample and also performed a stacking analysis combining the data from all GCs to investigate the hypothesis of a population of faint emitters. Assuming IC emission as the origin of the VHE gamma-ray signal from the direction of Terzan 5, we calculated the expected gamma-ray flux from each of the 15 GCs, based on their number of millisecond pulsars, their optical brightness and the energy density of background photon fields. Results. We did not detect significant VHE gamma-ray emission from any of the 15 GCs in either of the two analyses. Given the uncertainties related to the parameter determinations, the obtained flux upper limits allow to rule out the simple IC/msPSR scaling model for NGC6388 and NGC7078. The upper limits derived from the stacking analyses are factors between 2 and 50 below the flux predicted by the simple leptonic scaling model, depending on the assumed source extent and the dominant target photon fields. Therefore, Terzan 5 still remains exceptional among all GCs, as the VHE gamma-ray emission either arises from extra-ordinarily efficient leptonic processes, or from a recent catastrophic event, or is even unrelated to the GC itself.
KW  - globular clusters: general
KW  - radiation mechanisms: non-thermal
KW  - pulsars: general
KW  - gamma rays: general
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201220719
SN  - 0004-6361
VL  - 551
PB  - EDP SCIENCES S A
CY  - LES ULIS CEDEX A
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fuessling, M.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, Markus
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Kolitzus, D.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Oakes, L.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
T1  - HESS observations of the binary system PSR B1259-63/LS 2883 around the 2010/2011 periastron passage
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Aims. We present very high energy (VHE; E > 100 GeV) data from the gamma-ray binary system PSR B1259-63/LS 2883 taken around its periastron passage on 15th of December 2010 with the High Energy Stereoscopic System (H. E. S. S.) of Cherenkov Telescopes. We aim to search for a possible TeV counterpart of the GeV flare detected by the Fermi LAT. In addition, we aim to study the current periastron passage in the context of previous observations taken at similar orbital phases, testing the repetitive behaviour of the source.
 Methods. Observations at VHEs were conducted with H.E.S.S. from 9th to 16th of January 2011. The total dataset amounts to similar to 6 h of observing time. The data taken around the 2004 periastron passage were also re-analysed with the current analysis techniques in order to extend the energy spectrum above 3 TeV to fully compare observation results from 2004 and 2011.
 Results. The source is detected in the 2011 data at a significance level of 11.5 sigma revealing an averaged integral flux above 1 TeV of (1.01 +/- 0.18(stat) +/- 0.20(sys)) x 10(-12) cm(-2) s(-1). The differential energy spectrum follows a power-law shape with a spectral index Gamma = 2.92 +/- 0.30(stat) +/- 0.20(sys) and a flux normalisation at 1 TeV of N-0 = (1.95 +/- 0.32(stat) +/- 0.39(sys)) x 10(-12) TeV-1 cm(-2) s(-1). The measured light curve does not show any evidence for variability of the source on the daily scale. The re-analysis of the 2004 data yields results compatible with the published ones. The differential energy spectrum measured up to similar to 10 TeV is consistent with a power law with a spectral index Gamma = 2.81 +/- 0.10(stat) +/- 0.20(sys) and a flux normalisation at 1 TeV of N-0 = (1.29 +/- 0.08(stat) +/- 0.26(sys)) x 10(-12) TeV-1 cm(-2) s(-1).
 Conclusions. The measured integral flux and the spectral shape of the 2011 data are compatible with the results obtained around previous periastron passages. The absence of variability in the H.E.S.S. data indicates that the GeV flare observed by Fermi LAT in the time period covered also by H.E.S.S. observations originates in a different physical scenario than the TeV emission. Moreover, the comparison of the new results to the results from the 2004 observations made at a similar orbital phase provides a stronger evidence of the repetitive behaviour of the source.
KW  - gamma rays: general
KW  - pulsars: individual: PSR B1259-63
KW  - X-rays: binaries
KW  - stars: individual: LS 2883
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201220612
SN  - 0004-6361
VL  - 551
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Behera, B.
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O&rsquo
A1  - C., 
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fussling, Matthias
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M. -H.
A1  - Grudzinska, M.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Kolitzus, D.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
A1  - Pelat, D.
T1  - Discovery of TeV gamma-ray emission from PKS 0447-439 and derivation of
 an upper limit on its redshift
JF  - ASTRONOMY & ASTROPHYSICS
N2  - Very high-energy gamma-ray emission from PKS 0447-439 was detected with the H. E. S. S. Cherenkov telescope array in December 2009. This blazar is one of the brightest extragalactic objects in the Fermi bright source list and has a hard spectrum in the MeV to GeV range. In the TeV range, a photon index of 3.89 +/- 0.37 (stat) +/- 0.22 (sys) and a flux normalisation at 1 TeV, phi(1) (TeV) = (3.5 +/- 1.1(stat) +/- 0.9(sys)) x 10(-13) cm(-2) s(-1) TeV-1 were found. The detection with H. E. S. S. triggered observations in the X-ray band with the Swift and RXTE telescopes. Simultaneous UV and optical data from Swift UVOT and data from the optical telescopes ATOM and ROTSE are also available. The spectrum and light curve measured with H. E. S. S. are presented and compared to the multi-wavelength data at lower energies. A rapid flare is seen in the Swift XRT and RXTE data, together with a flux variation in the UV band, at a time scale of the order of one day. A firm upper limit of z < 0.59 on the redshift of PKS 0447-439 is derived from the combined Fermi-LAT and H. E. S. S. data, given the assumptions that there is no upturn in the intrinsic spectrum above the Fermi-LAT energy range and that absorption on the extragalactic background light (EBL) is not weaker than the lower limit provided by current models. The spectral energy distribution is well described by a simple one-zone synchrotron self-Compton scenario, if the redshift of the source is less than z less than or similar to 0.4.
KW  - galaxies: active
KW  - BL Lacertae objects: individual: PKS 0447-439
KW  - radiation mechanisms: non-thermal
KW  - gamma rays: galaxies
Y1  - 2013
U6  - https://doi.org/10.1051/0004-6361/201321108
SN  - 0004-6361
VL  - 552
IS  - 4
PB  - EDP SCIENCES S A
CY  - LES ULIS CEDEX A
ER  - 
TY  - JOUR
A1  - Abramowski, Attila
A1  - Acero, F.
A1  - Aharonian, Felix A.
A1  - Akhperjanian, A. G.
A1  - Anton, Gisela
A1  - Balenderan, Shangkari
A1  - Balzer, Arnim
A1  - Barnacka, Anna
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Bernlöhr, K.
A1  - Birsin, E.
A1  - Biteau, Jonathan
A1  - Bochow, A.
A1  - Boisson, Catherine
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Brucker, J.
A1  - Brun, Francois
A1  - Brun, Pierre
A1  - Bulik, Tomasz
A1  - Carrigan, Svenja
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chadwick, Paula M.
A1  - Chaves, Ryan C. G.
A1  - Cheesebrough, A.
A1  - Colafrancesco, Sergio
A1  - Cologna, Gabriele
A1  - Conrad, Jan
A1  - Couturier, C.
A1  - Dalton, M.
A1  - Daniel, M. K.
A1  - Davids, I. D.
A1  - Degrange, B.
A1  - Deil, C.
A1  - deWilt, P.
A1  - Dickinson, H. J.
A1  - Djannati-Ataï, A.
A1  - Domainko, W.
A1  - Drury, L. O'C.
A1  - Dubus, G.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Dyrda, M.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Espigat, P.
A1  - Fallon, L.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Feinstein, F.
A1  - Fernandes, M. V.
A1  - Fernandez, D.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Foerster, A.
A1  - Fussling, Matthias
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Gast, H.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Glueck, B.
A1  - Goering, D.
A1  - Grondin, M. -H.
A1  - Haeffner, S.
A1  - Hague, J. D.
A1  - Hahn, J.
A1  - Hampf, D.
A1  - Harris, J.
A1  - Heinz, S.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hillert, A.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hofverberg, P.
A1  - Holler, M.
A1  - Horns, D.
A1  - Jacholkowska, A.
A1  - Jahn, C.
A1  - Jamrozy, M.
A1  - Jung, I.
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katz, U.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluzniak, W.
A1  - Kneiske, T.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kossakowski, R.
A1  - Krayzel, F.
A1  - Krueger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lefaucheur, J.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Lennarz, D.
A1  - Lohse, T.
A1  - Lopatin, A.
A1  - Lu, C. -C.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Masbou, J.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - McComb, T. J. L.
A1  - Medina, M. C.
A1  - Mehault, J.
A1  - Menzler, U.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Moulin, Emmanuel
A1  - Naumann, C. L.
A1  - Naumann-Godo, M.
A1  - de Naurois, M.
A1  - Nedbal, D.
A1  - Nekrassov, D.
A1  - Nguyen, N.
A1  - Niemiec, J.
A1  - Nolan, S. J.
A1  - Ohm, S.
A1  - Awilhelmi, E. de Ona
A1  - Opitz, B.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Arribas, M. Paz
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perez, J.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pita, S.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raue, M.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - de los Reyes, R.
A1  - Rieger, F.
A1  - Ripken, J.
A1  - Rob, L.
A1  - Rosier-Lees, S.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Sahakian, V.
A1  - Sanchez, David M.
A1  - Santangelo, A.
A1  - Schlickeiser, R.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwarzburg, S.
A1  - Schwemmer, S.
A1  - Sheidaei, F.
A1  - Skilton, J. L.
A1  - Sol, H.
A1  - Spengler, G.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stinzing, F.
A1  - Stycz, K.
A1  - Sushch, Iurii
A1  - Szostek, A.
A1  - Tavernet, J. -P.
A1  - Terrier, R.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Valerius, K.
A1  - van Eldik, C.
A1  - Vasileiadis, G.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Voelk, H. J.
A1  - Volpe, F.
A1  - Vorobiov, S.
A1  - Vorster, M.
A1  - Wagner, S. J.
A1  - Ward, M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Wouters, D.
A1  - Zacharias, M.
A1  - Zajczyk, A.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zechlin, H. -S.
T1  - Search for Photon-Linelike Signatures from Dark Matter Annihilations with H.E.S.S.
JF  - Physical review letters
N2  - Gamma-ray line signatures can be expected in the very-high-energy (E-gamma > 100 GeV) domain due to self-annihilation or decay of dark matter (DM) particles in space. Such a signal would be readily distinguishable from astrophysical gamma-ray sources that in most cases produce continuous spectra that span over several orders of magnitude in energy. Using data collected with the H. E. S. S. gamma-ray instrument, upper limits on linelike emission are obtained in the energy range between similar to 500 GeV and similar to 25 TeV for the central part of the Milky Way halo and for extragalactic observations, complementing recent limits obtained with the Fermi-LAT instrument at lower energies. No statistically significant signal could be found. For monochromatic gamma-ray line emission, flux limits of (2 x 10(-7)-2 x 10(-5)) m(-2)s(-1)sr(-1) and (1 x 10(-8)- 2 x 10(-6)) m(-2)s(-1)sr(-1) are obtained for the central part of the Milky Way halo and extragalactic observations, respectively. For a DM particle mass of 1 TeV, limits on the velocity- averaged DM annihilation cross section <sigma upsilon >(chi chi ->gamma gamma) reach similar to 10(-27)cm(3)s(-1), based on the Einasto parametrization of the Galactic DM halo density profile. DOI: 10.1103/PhysRevLett.110.041301
Y1  - 2013
U6  - https://doi.org/10.1103/PhysRevLett.110.041301
SN  - 0031-9007
VL  - 110
IS  - 4
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - GEN
A1  - Liu, S.
A1  - Kuschpel, M. S.
A1  - Schad, Daniel
A1  - Heinzel, Stephan
A1  - Rapp, Michael Armin
A1  - Heinz, A.
T1  - Effects of rest on learning processes
T2  - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Y1  - 2018
U6  - https://doi.org/10.1016/j.euroneuro.2017.12.099
SN  - 0924-977X
SN  - 1873-7862
VL  - 28
SP  - S67
EP  - S68
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Heinz, A.
A1  - Voss, M.
A1  - Lawrie, S. M.
A1  - Mishara, A.
A1  - Bauer, M.
A1  - Gallinat, Jürgen
A1  - Juckel, G.
A1  - Lang, U.
A1  - Rapp, Michael Armin
A1  - Falkai, P.
A1  - Strik, W.
A1  - Krystal, J.
A1  - Abi-Dargham, A.
A1  - Galderisi, S.
T1  - Shall we really say goodbye to first rank symptoms?
JF  - European psychiatry : the journal of the Association of European Psychiatrists
N2  - Background: First rank symptoms (FRS) of schizophrenia have been used for decades for diagnostic purposes. In the new version of the DSM-5, the American Psychiatric Association (APA) has abolished any further reference to FRS of schizophrenia and treats them like any other "criterion A' symptom (e.g. any kind of hallucination or delusion) with regard to their diagnostic implication. The ICD-10 is currently under revision and may follow suit. In this review, we discuss central points of criticism that are directed against the continuous use of first rank symptoms (FRS) to diagnose schizophrenia.
KW  - First rank symptoms
KW  - Schizophrenia
KW  - ICD
KW  - DSM
KW  - Self-disorder
Y1  - 2016
U6  - https://doi.org/10.1016/j.eurpsy.2016.04.010
SN  - 0924-9338
SN  - 1778-3585
VL  - 37
SP  - 8
EP  - 13
PB  - Elsevier
CY  - Paris
ER  - 
TY  - JOUR
A1  - Sommer, C.
A1  - Garbusow, Maria
A1  - Juenger, E.
A1  - Pooseh, S.
A1  - Bernhardt, Nadine
A1  - Birkenstock, J.
A1  - Schad, Daniel
A1  - Jabs, B.
A1  - Gloeckler, T.
A1  - Huys, Quentin J. M.
A1  - Heinz, A.
A1  - Smolka, Michael N.
A1  - Zimmermann, Ulrich S.
T1  - Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence
JF  - Translational Psychiatry
N2  - Alcohol-related cues acquire incentive salience through Pavlovian conditioning and then can markedly affect instrumental behavior of alcohol-dependent patients to promote relapse. However, it is unclear whether similar effects occur with alcohol-unrelated cues. We tested 116 early-abstinent alcohol-dependent patients and 91 healthy controls who completed a delay discounting task to assess choice impulsivity, and a Pavlovian-to-instrumental transfer (PIT) paradigm employing both alcohol-unrelated and alcohol-related stimuli. To modify instrumental choice behavior, we tiled the background of the computer screen either with conditioned stimuli (CS) previously generated by pairing abstract pictures with pictures indicating monetary gains or losses, or with pictures displaying alcohol or water beverages. CS paired to money gains and losses affected instrumental choices differently. This PIT effect was significantly more pronounced in patients compared to controls, and the group difference was mainly driven by highly impulsive patients. The PIT effect was particularly strong in trials in which the instrumental stimulus required inhibition of instrumental response behavior and the background CS was associated to monetary gains. Under that condition, patients performed inappropriate approach behavior, contrary to their previously formed behavioral intention. Surprisingly, the effect of alcohol and water pictures as background stimuli resembled that of aversive and appetitive CS, respectively. These findings suggest that positively valenced background CS can provoke dysfunctional instrumental approach behavior in impulsive alcohol-dependent patients. Consequently, in real life they might be easily seduced by environmental cues to engage in actions thwarting their long-term goals. Such behaviors may include, but are not limited to, approaching alcohol.
Y1  - 2017
U6  - https://doi.org/10.1038/tp.2017.158
SN  - 2158-3188
VL  - 7
SP  - 1209
EP  - 1222
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - GEN
A1  - Heinz, Wolfgang S.
T1  - Militär und Transition zur Demokratie in Lateinamerika : ein Rück- und Ausblick
T1  - Military and transition to democracy in Latin America
N2  - Since the beginning of the 1970s a lot of countries in Latin America has been starting the transition to democracy. The article analyses the role played by the military in this process, especially the effects of civildemocratic governments – sometimes failing in – gaining power over the military. It is described how and why the army occasionally kept their independence from the civil power and how this influenced the consolidation of democracy.
KW  - Lateinamerika
KW  - Militär
KW  - Übergang
KW  - zivil-militärische Beziehungen
KW  - Demokratie
KW  - Latin America
KW  - military
KW  - transition
KW  - civil-military relations
KW  - democracy
Y1  - 2005
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-48299
ER  - 
TY  - GEN
A1  - Garbusow, Maria
A1  - Sommer, Christian
A1  - Nebe, Stephan
A1  - Sebold, Miriam Hannah
A1  - Kuitunen-Paul, Sören
A1  - Wittchen, Hans-Ulrich
A1  - Smolka, Michael N.
A1  - Zimmermann, Ulrich S.
A1  - Rapp, Michael Armin
A1  - Huys, Quentin J. M.
A1  - Schlagenhauf, Florian
A1  - Heinz, Andreas
T1  - Multi-level evidence of general pavlovian-to-instrumental transfer in alcohol use disorder
T2  - Alcoholism : clinical and experimental research ; the official journal of the American Medical Society on Alcoholism and the Research Society on Alcoholism
Y1  - 2018
SN  - 0145-6008
SN  - 1530-0277
VL  - 42
SP  - 128A
EP  - 128A
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Garbusow, Maria
A1  - Sommer, C.
A1  - Nebe, S.
A1  - Sebold, Miriam Hannah
A1  - Kuitunen-Paul, Sören
A1  - Wittchen, H. U.
A1  - Smolka, M.
A1  - Zimmermann, U.
A1  - Rapp, Michael Armin
A1  - Huys, Q.
A1  - Schlagenhauf, Florian
A1  - Heinz, A.
T1  - Pavlovian-instrumental transfer in the course of alcohol use disorder
T2  - European psychiatry : the journal of the Association of European Psychiatrists
N2  - Background: Pavlovian processes are thought to play an important role in the development, maintenance and relapse of alcohol dependence, possibly by influencing and usurping on- going thought and behavior. The influence of Pavlovian stimuli on on-going behavior is paradigmatically measured by Pavlovian-to-instrumental-transfer (PIT) tasks. These involve multiple stages and are complex. Whether increased PIT is involved in human alcohol
dependence is uncertain. We therefore aimed to establish and validate a modified PIT paradigm that would be robust, consistent, and tolerated by healthy controls as well as by patients suffering from alcohol dependence, and to explore whether alcohol dependence is associated with enhanced Pavlovian-Instrumental transfer.

Methods: 32 recently detoxified alcohol-dependent patients and 32 age and gender matched healthy controls performed a PIT task with instrumental go/no-go approach behaviours. The task involved both Pavlovian stimuli associated with monetary rewards and losses, and images of drinks.

Results: Both patients and healthy controls showed a robust and temporally stable PIT effect. Strengths of PIT effects to drug-related and monetary conditioned stimuli were highly correlated. Patients more frequently showed a PIT effect and the effect was stronger in response to aversively conditioned CSs (conditioned suppression), but there was no group difference in response to appetitive CSs.

Conclusion: The implementation of PIT has favorably robust properties in chronic alcohol- dependent patients and in healthy controls. It shows internal consistency between monetary and drug-related cues. The findings support an association of alcohol dependence with an increased propensity towards PIT.
Y1  - 2018
SN  - 0924-9338
SN  - 1778-3585
VL  - 48
SP  - S546
EP  - S546
PB  - Elsevier
CY  - ISSY-LES-MOULINEAUX
ER  - 
TY  - JOUR
A1  - Sekutowicz, Maria
A1  - Guggenmos, Matthias
A1  - Kuitunen-Paul, Sören
A1  - Garbusow, Maria
A1  - Sebold, Miriam Hannah
A1  - Pelz, Patricia
A1  - Priller, Josef
A1  - Wittchen, Hans-Ulrich
A1  - Smolka, Michael N.
A1  - Zimmermann, Ulrich S.
A1  - Heinz, Andreas
A1  - Sterzer, Philipp
A1  - Schmack, Katharina
T1  - Neural Response Patterns During Pavlovian-to-Instrumental Transfer Predict Alcohol Relapse and Young Adult Drinking
JF  - Biological psychiatry : a journal of psychiatric neuroscience and therapeutics ; a publication of the Society of Biological Psychiatry
N2  - BACKGROUND: Pavlovian-to-instrumental transfer (PIT) describes the influence of conditioned stimuli on instrumental behaviors and is discussed as a key process underlying substance abuse. Here, we tested whether neural responses during alcohol-related PIT predict future relapse in alcohol-dependent patients and future drinking behavior in adolescents. METHODS: Recently detoxified alcohol-dependent patients (n = 52) and young adults without dependence (n = 136) underwent functional magnetic resonance imaging during an alcohol-related PIT paradigm, and their drinking behavior was assessed in a 12-month follow-up. To predict future drinking behavior from PIT activation patterns, we used a multivoxel classification scheme based on linear support vector machines. RESULTS: When training and testing the classification scheme in patients, PIT activation patterns predicted future relapse with 71.2% accuracy. Feature selection revealed that classification was exclusively based on activation patterns in medial prefrontal cortex. To probe the generalizability of this functional magnetic resonance imaging-based prediction of future drinking behavior, we applied the support vector machine classifier that had been trained on patients to PIT functional magnetic resonance imaging data from adolescents. An analysis of cross-classification predictions revealed that those young social drinkers who were classified as abstainers showed a greater reduction in alcohol consumption at 12-month follow-up than those classified as relapsers (Delta = -24.4 +/- 6.0 g vs. -5.7 +/- 3.6 g; p = .019). CONCLUSIONS: These results suggest that neural responses during PIT could constitute a generalized prognostic marker for future drinking behavior in established alcohol use disorder and in at-risk states.
KW  - Alcohol dependence
KW  - Future drinking behavior
KW  - Multivoxel classification
KW  - Pavlovian-to-instrumental transfer
KW  - Relapse
Y1  - 2019
U6  - https://doi.org/10.1016/j.biopsych.2019.06.028
SN  - 0006-3223
SN  - 1873-2402
VL  - 86
IS  - 11
SP  - 857
EP  - 863
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Friedel, Eva
A1  - Sebold, Miriam Hannah
A1  - Kuitunen-Paul, Sören
A1  - Nebe, Stephan
A1  - Veer, Ilya M.
A1  - Zimmermann, Ulrich S.
A1  - Schlagenhauf, Florian
A1  - Smolka, Michael N.
A1  - Rapp, Michael Armin
A1  - Walter, Henrik
A1  - Heinz, Andreas
T1  - How Accumulated Real Life Stress Experience and Cognitive Speed Interact on Decision-Making Processes
JF  - Frontiers in human neuroscienc
N2  - Rationale: Advances in neurocomputational modeling suggest that valuation systems for goal-directed (deliberative) on one side, and habitual (automatic) decision-making on the other side may rely on distinct computational strategies for reinforcement learning, namely model-free vs. model-based learning. As a key theoretical difference, the model-based system strongly demands cognitive functions to plan actions prospectively based on an internal cognitive model of the environment, whereas valuation in the model-free system relies on rather simple learning rules from operant conditioning to retrospectively associate actions with their outcomes and is thus cognitively less demanding. Acute stress reactivity is known to impair model-based but not model-free choice behavior, with higher working memory capacity protecting the model-based system from acute stress. However, it is not clear which impact accumulated real life stress has on model-free and model-based decision systems and how this influence interacts with cognitive abilities. Methods: We used a sequential decision-making task distinguishing relative contributions of both learning strategies to choice behavior, the Social Readjustment Rating Scale questionnaire to assess accumulated real life stress, and the Digit Symbol Substitution Test to test cognitive speed in 95 healthy subjects. Results: Individuals reporting high stress exposure who had low cognitive speed showed reduced model-based but increased model-free behavioral control. In contrast, subjects exposed to accumulated real life stress with high cognitive speed displayed increased model-based performance but reduced model-free control. Conclusion: These findings suggest that accumulated real life stress exposure can enhance reliance on cognitive speed for model-based computations, which may ultimately protect the model-based system from the detrimental influences of accumulated real life stress. The combination of accumulated real life stress exposure and slower information processing capacities, however, might favor model-free strategies. Thus, the valence and preference of either system strongly depends on stressful experiences and individual cognitive capacities.
KW  - chronic stress
KW  - model-based learning
KW  - model-free learning
KW  - decision making
KW  - cognitive speed
KW  - real-life events
Y1  - 2017
U6  - https://doi.org/10.3389/fnhum.2017.00302
SN  - 1662-5161
VL  - 11
SP  - 1
EP  - 9
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - GEN
A1  - Sebold, Miriam Hannah
A1  - Garbusow, Maria
A1  - Nebe, S.
A1  - Sundmacher, L.
A1  - Kuitunen-Paul, Sören
A1  - Wittchen, H. U.
A1  - Smolka, M.
A1  - Zimmermann, U.
A1  - Rapp, Michael Armin
A1  - Huys, Q.
A1  - Schlagenhauf, Florian
A1  - Heinz, A.
T1  - From goals to habits in alcohol dependence
BT  - association with treatment outcome and cognitive bias modification training
T2  - European psychiatry : the journal of the Association of European Psychiatrists
Y1  - 2018
SN  - 0924-9338
SN  - 1778-3585
VL  - 48
SP  - S274
EP  - S274
PB  - Elsevier
CY  - Paris
ER  - 
TY  - JOUR
A1  - Heinz, Wolfgang S.
A1  - Homburger, Zine
ED  - Zimmermann, Andreas
T1  - Die Rolle des UN-Hochkommissariats für Menschenrechte (OHCHR) im UN-Menschenrechtsschutz
BT  - Entwicklungen, Probleme und Perspektiven
JF  - Konzepte für die Reform der Vereinten Nationen : 12. Potsdamer UNO-Konferenz am 28.Juni 2014
N2  - I. Gründung, Aufgaben und Struktur des Hochkommissariats
II. Zur Rolle des OHCHR im und gegenüber dem Menschenrechtsrat
III. Zu Erfolgschancen von Feldmissionen in eher schwierigen Ländern: China, Russische Föderation, Afghanistan, Sudan und Kolumbien
IV. Zur Frage der politischen Unabhängigkeit des OHCHR
V. Schlussfolgerungen und Ausblick
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-80177
VL  - 2015
IS  - 11
SP  - 69
EP  - 98
ER  - 
TY  - JOUR
A1  - Goldmann, Daniela
A1  - Mahlstedt, S.
A1  - Janietz, Dietmar
A1  - Busch, P.
A1  - Schmidt, C.
A1  - Stracke, A.
A1  - Wendorff, Joachim Heinz
T1  - Mesomorphic donor-acceptor twin molecules with covalently linked sheet-like pentaalkyne and nitrofluorenone subunits
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Nettels, Daniel
A1  - Müller-Späth, Sonja
A1  - Küster, Frank
A1  - Hofmann, Hagen
A1  - Haenni, Domminik
A1  - Rüegger, Stefan
A1  - Reymond, Luc
A1  - Hoffmann, Armin S.
A1  - Kubelka, Jan
A1  - Heinz, Benjamin
A1  - Gast, Klaus
A1  - Best, Robert B.
A1  - Schuler, Benjamin
T1  - Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins
N2  - We used single-molecule FRET in combination with other biophysical methods and molecular simulations to investigate the effect of temperature on the dimensions of unfolded proteins. With singlemolecule FRET, this question can be addressed even under nearnative conditions, where most molecules are folded, allowing us to probe a wide range of denaturant concentrations and temperatures. We find a compaction of the unfolded state of a small cold shock protein with increasing temperature in both the presence and the absence of denaturant, with good agreement between the results from single-molecule FRET and dynamic light scattering. Although dissociation of denaturant from the polypeptide chain with increasing temperature accounts for part of the compaction, the results indicate an important role for additional temperaturedependent interactions within the unfolded chain. The observation of a collapse of a similar extent in the extremely hydrophilic, intrinsically disordered protein prothymosin suggests that the hydrophobic effect is not the sole source of the underlying interactions. Circular dichroism spectroscopy and replica exchange molecular dynamics simulations in explicit water show changes in secondary structure content with increasing temperature and suggest a contribution of intramolecular hydrogen bonding to unfolded state collapse.
Y1  - 2009
UR  - http://www.pnas.org/content/106/49/20740.full.pdf+html
SN  - 0027-8424
ER  - 
TY  - CHAP
A1  - Völler, Heinz
A1  - Salzwedel, Annett
A1  - Reibis, Rona Katharina
A1  - Kaminski, S.
A1  - Buhlert, Hermann
A1  - Eichler, Sarah
A1  - Wegscheider, Karl
T1  - Age and fitness level are strongest limitations of exercise capacity during inpatient cardiac rehabilitation
T2  - European heart journal
Y1  - 2014
SN  - 0195-668X
SN  - 1522-9645
VL  - 35
SP  - 899
EP  - 899
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Roehrig, B.
A1  - Nosper, M.
A1  - Linck-Eleftheriadis, S.
A1  - Strandt, G.
A1  - Salzwedel, Annett
A1  - Völler, Heinz
T1  - Method of the assessment of patients Outcome in cardiac rehabilitation by means of quality indicators - a description of the method
JF  - Die Rehabilitation : Zeitschrift für Praxis und Forschung in der Rehabilitation
N2  - Introduction: Cardiac rehabilitation is designed for patients suffering from cardiovascular diseases or functional disabilities. The aim of a cardiac rehabilitation is to improve overall physical health, psychological well-being, physical function, the ability to participate in social life and help patients to change their habits. Regarding the heterogeneity of these aims measuring of the effect of cardiac rehabilitation is still a challenge. This study recommends a concept to assess the effects of cardiac rehabilitation regarding the individual change of relevant quality indicators.
 Methods: With EVA-Reha; cardiac rehabilitation the Medical Advisory Service of Statutory Health Insurance Funds in Rhineland-Palatinate, Alzey (MDK Rheinland-Pfalz) developed a software to collect data set including sociodemographic and diagnostic data and also the results of specific assessments. The project was funded by the Techniker Krankenkasse, Hamburg, and supported by participating rehabilitation centers. From 01. July 2010 to 30. June 2011 1309 patients (age 71.5 years, 76.1% men) from 13 rehabilitation centers were consecutively enrolled. 13 quality indicators in 3 scales were developed for evaluation of cardiac rehabilitation: 1) cardiovascular risk factors (blood pressure, LDL cholesterol, triglycerides), 2) exercise capacity (resting heart rate, maximal exercise capacity, maximal walking distance, heart failure [NYHA classification], and angina pectoris [CCS classification]) and 3) subjective health (IRES-24: pain, somatic health, psychological wellbeing and depression as well as anxiety on the HADS). The study was prospective; data of patients were assessed at entry and discharge of rehabilitation. To measure the success of rehabilitation each parameter was graded in severity classes at entry and discharge. For each of the 13 quality indicators changes of severity class were rated in a rating matrix. For indicators without a requirement for medical care neither at entry nor at discharge no rating was performed.
 Results: The grading into severity classes as well as the minimal important differences were given for the 13 quality indicators. The result of rehabilitation can be demonstrated in suitable form by means of rating of the 13 quality indicators according to a clinical population. The rating model differs well between clinically changed and unchanged patients for the quality indicators.
 Conclusion: The result of cardiac rehabilitation can be assessed with 13 quality indicators measured at entry and discharge of the rehabilitation program. If a change into a more favorable category at the end of rehabilitation could be achieved it was counted as a success. The 13 quality indicators can be used to assess the individual result as well as the result of a population - e.g. all patients of a clinic in a specific time period. In addition, the assessment and rating of relevant quality indicators can be used for comparisons of rehabilitation centers.
KW  - cardiac rehabilitation
KW  - quality indicator
KW  - outcome
KW  - success
KW  - quality management
Y1  - 2014
U6  - https://doi.org/10.1055/s-0033-1341457
SN  - 0034-3536
SN  - 1439-1309
VL  - 53
IS  - 1
SP  - 31
EP  - 37
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Heinz, S.
A1  - Jung, I.
A1  - Stegmann, Christian
T1  - Systematic studies of the Richardson-Lucy deconvolution algorithm
 applied to VHE gamma data
JF  - ASTROPARTICLE PHYSICS
N2  - The Richardson-Lucy deconvolution algorithm was applied to astronomical images in the very high-energy regime with photon energies above 100 GeV. Through a systematic study with respect to source significance, background level and source morphology we were able to derive optimal deconvolution parameters. The results presented show that deconvolution makes it possible to study structural details well below the angular resolution of the very high-energy gamma-ray experiment. (C) 2012 Elsevier B.V. All rights reserved.
KW  - Very high energy gamma-ray astronomy
KW  - Deconvolution
Y1  - 2012
U6  - https://doi.org/10.1016/j.astropartphys.2012.05.013
SN  - 0927-6505
VL  - 36
IS  - 1
SP  - 146
EP  - 150
PB  - ELSEVIER SCIENCE BV
CY  - AMSTERDAM
ER  - 
TY  - JOUR
A1  - Hansen, Dominique
A1  - Dendale, Paul
A1  - Coninx, Karin
A1  - Vanhees, Luc
A1  - Piepoli, Massimo F.
A1  - Niebauer, Josef
A1  - Cornelissen, Veronique
A1  - Pedretti, Roberto
A1  - Geurts, Eva
A1  - Ruiz, Gustavo R.
A1  - Corra, Ugo
A1  - Schmid, Jean-Paul
A1  - Greco, Eugenio
A1  - Davos, Constantinos H.
A1  - Edelmann, Frank
A1  - Abreu, Ana
A1  - Rauch, Bernhard
A1  - Ambrosetti, Marco
A1  - Braga, Simona S.
A1  - Barna, Olga
A1  - Beckers, Paul
A1  - Bussotti, Maurizio
A1  - Fagard, Robert
A1  - Faggiano, Pompilio
A1  - Garcia-Porrero, Esteban
A1  - Kouidi, Evangelia
A1  - Lamotte, Michel
A1  - Neunhaeuserer, Daniel
A1  - Reibis, Rona Katharina
A1  - Spruit, Martijn A.
A1  - Stettler, Christoph
A1  - Takken, Tim
A1  - Tonoli, Cajsa
A1  - Vigorito, Carlo
A1  - Völler, Heinz
A1  - Doherty, Patrick
T1  - The European Association of Preventive Cardiology Exercise Prescription in Everyday Practice and Rehabilitative Training (EXPERT) tool: A digital training and decision support system for optimized exercise prescription in cardiovascular disease. Concept, definitions and construction methodology
JF  - European journal of preventive cardiology : the official ESC journal for primary & secondary cardiovascular prevention, rehabilitation and sports cardiology
N2  - Background Exercise rehabilitation is highly recommended by current guidelines on prevention of cardiovascular disease, but its implementation is still poor. Many clinicians experience difficulties in prescribing exercise in the presence of different concomitant cardiovascular diseases and risk factors within the same patient. It was aimed to develop a digital training and decision support system for exercise prescription in cardiovascular disease patients in clinical practice: the European Association of Preventive Cardiology Exercise Prescription in Everyday Practice and Rehabilitative Training (EXPERT) tool. Methods EXPERT working group members were requested to define (a) diagnostic criteria for specific cardiovascular diseases, cardiovascular disease risk factors, and other chronic non-cardiovascular conditions, (b) primary goals of exercise intervention, (c) disease-specific prescription of exercise training (intensity, frequency, volume, type, session and programme duration), and (d) exercise training safety advices. The impact of exercise tolerance, common cardiovascular medications and adverse events during exercise testing were further taken into account for optimized exercise prescription. Results Exercise training recommendations and safety advices were formulated for 10 cardiovascular diseases, five cardiovascular disease risk factors (type 1 and 2 diabetes, obesity, hypertension, hypercholesterolaemia), and three common chronic non-cardiovascular conditions (lung and renal failure and sarcopaenia), but also accounted for baseline exercise tolerance, common cardiovascular medications and occurrence of adverse events during exercise testing. An algorithm, supported by an interactive tool, was constructed based on these data. This training and decision support system automatically provides an exercise prescription according to the variables provided. Conclusion This digital training and decision support system may contribute in overcoming barriers in exercise implementation in common cardiovascular diseases.
KW  - Cardiovascular disease
KW  - rehabilitation
KW  - exercise training
KW  - training and decision support system
Y1  - 2017
U6  - https://doi.org/10.1177/2047487317702042
SN  - 2047-4873
SN  - 2047-4881
VL  - 24
SP  - 1017
EP  - 1031
PB  - Sage Publ.
CY  - London
ER  - 
TY  - JOUR
A1  - Garbusow, Maria
A1  - Schad, Daniel
A1  - Sommer, Christian
A1  - Juenger, Elisabeth
A1  - Sebold, Miriam Hannah
A1  - Friedel, Eva
A1  - Wendt, Jean
A1  - Kathmann, Norbert
A1  - Schlagenhauf, Florian
A1  - Zimmermann, Ulrich S.
A1  - Heinz, Andreas
A1  - Huys, Quentin J. M.
A1  - Rapp, Michael Armin
T1  - Pavlovian-to-instrumental transfer in alcohol dependence: a pilot study
JF  - Neuropsychobiology : international journal of experimental and clinical research in biological psychiatry, pharmacopsychiatry, Biological Psychology/Pharmacopsychology and Pharmacoelectroencephalography
N2  - Background: Pavlovian processes are thought to play an important role in the development, maintenance and relapse of alcohol dependence, possibly by influencing and usurping ongoing thought and behavior. The influence of pavlovian stimuli on ongoing behavior is paradigmatically measured by pavlovian-to-instrumental transfer (PIT) tasks. These involve multiple stages and are complex. Whether increased PIT is involved in human alcohol dependence is uncertain. We therefore aimed to establish and validate a modified PIT paradigm that would be robust, consistent and tolerated by healthy controls as well as by patients suffering from alcohol dependence, and to explore whether alcohol dependence is associated with enhanced PIT. Methods: Thirty-two recently detoxified alcohol-dependent patients and 32 age- and gender-matched healthy controls performed a PIT task with instrumental go/no-go approach behaviors. The task involved both pavlovian stimuli associated with monetary rewards and losses, and images of drinks. Results: Both patients and healthy controls showed a robust and temporally stable PIT effect. Strengths of PIT effects to drug-related and monetary conditioned stimuli were highly correlated. Patients more frequently showed a PIT effect, and the effect was stronger in response to aversively conditioned CSs (conditioned suppression), but there was no group difference in response to appetitive CSs. Conclusion: The implementation of PIT has favorably robust properties in chronic alcohol-dependent patients and in healthy controls. It shows internal consistency between monetary and drug-related cues. The findings support an association of alcohol dependence with an increased propensity towards PIT.
KW  - Pavlovian-to-instrumental transfer
KW  - Alcohol dependence
KW  - Human
Y1  - 2014
U6  - https://doi.org/10.1159/000363507
SN  - 0302-282X
SN  - 1423-0224
VL  - 70
IS  - 2
SP  - 111
EP  - 121
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Liu, Shuyan
A1  - Kuschpel, Maxim S.
A1  - Schad, Daniel
A1  - Heinz, Andreas
A1  - Rapp, Michael Armin
T1  - Differential Effects of Music and Video Gaming During Breaks on Auditory and Visual Learning
JF  - Cyberpsychology, behavior and social networking
N2  - The interruption of learning processes by breaks filled with diverse activities is common in everyday life. This study investigated the effects of active computer gaming and passive relaxation (rest and music) breaks on auditory versus visual memory performance. Young adults were exposed to breaks involving (a) open eyes resting, (b) listening to music, and (c) playing a video game, immediately after memorizing auditory versus visual stimuli. To assess learning performance, words were recalled directly after the break (an 8:30 minute delay) and were recalled and recognized again after 7 days. Based on linear mixed-effects modeling, it was found that playing the Angry Birds video game during a short learning break impaired long-term retrieval in auditory learning but enhanced long-term retrieval in visual learning compared with the music and rest conditions. These differential effects of video games on visual versus auditory learning suggest specific interference of common break activities on learning.
Y1  - 2015
U6  - https://doi.org/10.1089/cyber.2015.0140
SN  - 2152-2715
SN  - 2152-2723
VL  - 18
IS  - 11
SP  - 647
EP  - 653
PB  - Liebert
CY  - New Rochelle
ER  - 
TY  - CHAP
A1  - Schad, Daniel
A1  - Juenger, Elisabeth
A1  - Sebold, Miriam Hannah
A1  - Garbusow, Maria
A1  - Bernhart, Nadine
A1  - Javadi, Amir Homayoun
A1  - Zimmermann, Ulrich S.
A1  - Smolka, Michael N.
A1  - Heinz, Andreas
A1  - Rapp, Michael Armin
A1  - Huys, Quentin J. M.
T1  - Smart goals, slow habits? Individual differences in processing speed and working memory capacity moderate the balance between habitual and goal-directed choice behavior
T2  - Cognitive processing : international quarterly of cognitive science
Y1  - 2014
SN  - 1612-4782
SN  - 1612-4790
VL  - 15
IS  - 1
SP  - S62
EP  - S62
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - GEN
A1  - Kuschpel, Maxim S.
A1  - Liu, Shuyan
A1  - Schad, Daniel
A1  - Heinzel, Stephan
A1  - Heinz, Andreas
A1  - Rapp, Michael Armin
T1  - Differential effects of wakeful rest, music and video game playing on working memory performance in the n-back task
N2  - The interruption of learning processes by breaks filled with diverse activities is common in everyday life. We investigated the effects of active computer gaming and passive relaxation (rest and music) breaks on working memory performance. Young adults were exposed to breaks involving (i) eyes-open resting, (ii) listening to music and (iii) playing the video game “Angry Birds” before performing the n-back working memory task. Based on linear mixed-effects modeling, we found that playing the “Angry Birds” video game during a short learning break led to a decline in task performance over the course of the task as compared to eyes-open resting and listening to music, although overall task performance was not impaired. This effect was associated with high levels of daily mind wandering and low self-reported ability to concentrate. These findings indicate that video games can negatively affect working memory performance over time when played in between learning tasks. We suggest further investigation of these effects because of their relevance to everyday activity.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 280 
KW  - attention
KW  - break interventions
KW  - cognitive resources
KW  - computer games
KW  - mind wandering
KW  - mozart effect
KW  - working memory
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-85151
ER  - 
TY  - GEN
A1  - Liu, Shuyan
A1  - Schad, Daniel
A1  - Kuschpel, Maxim S.
A1  - Rapp, Michael Armin
A1  - Heinz, Andreas
T1  - Music and Video Gaming during Breaks
BT  - Influence on Habitual versus Goal-Directed Decision Making
N2  - Different systems for habitual versus goal-directed control are thought to underlie human decision-making. Working memory is known to shape these decision-making systems and
their interplay, and is known to support goal-directed decision making even under stress. Here, we investigated if and how decision systems are differentially influenced by breaks filled with diverse everyday life activities known to modulate working memory performance. We used a within-subject design where young adults listened to music and played a video game during breaks interleaved with trials of a sequential two-step Markov decision task, designed to assess habitual as well as goal-directed decision making. Based on a neurocomputational model of task performance, we observed that for individuals with a rather limited working memory capacity video gaming as compared to music reduced reliance on the goal-directed decision-making system, while a rather large working memory capacity prevented such a decline. Our findings suggest differential effects of everyday activities on key decision-making processes.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 289 
KW  - Cognition
KW  - Cognitive impairment
KW  - Decision making
KW  - Games
KW  - Learning
KW  - Music cognition
KW  - Video games
KW  - Working memory
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-90700
SP  - 1
EP  - 12
ER  - 
TY  - JOUR
A1  - Kuschpel, Maxim S.
A1  - Liu, Shuyan
A1  - Schad, Daniel
A1  - Heinzel, Stephan
A1  - Heinz, Andreas
A1  - Rapp, Michael Armin
T1  - Differential effects of wakeful rest, music and video game playing on working memory performance in the n-back task
JF  - Frontiers in psychology
N2  - The interruption of learning processes by breaks filled with diverse activities is common in everyday life. We investigated the effects of active computer gaming and passive relaxation (rest and music) breaks on working memory performance. Young adults were exposed to breaks involving (i) eyes-open resting, (ii) listening to music and (iii) playing the video game “Angry Birds” before performing the n-back working memory task. Based on linear mixed-effects modeling, we found that playing the “Angry Birds” video game during a short learning break led to a decline in task performance over the course of the task as compared to eyes-open resting and listening to music, although overall task performance was not impaired. This effect was associated with high levels of daily mind wandering and low self-reported ability to concentrate. These findings indicate that video games can negatively affect working memory performance over time when played in between learning tasks. We suggest further investigation of these effects because of their relevance to everyday activity.
KW  - break interventions
KW  - computer games
KW  - mozart effect
KW  - working memory
KW  - attention
KW  - cognitive resources
KW  - mind wandering
Y1  - 2015
U6  - https://doi.org/10.3389/fpsyg.2015.01683
SN  - 1664-1078
IS  - 6
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Liu, Shuyan
A1  - Schad, Daniel
A1  - Kuschpel, Maxim S.
A1  - Rapp, Michael Armin
A1  - Heinz, Andreas
T1  - Music and Video Gaming during Breaks
BT  - Influence on Habitual versus Goal-Directed Decision Making
JF  - PLoS one
N2  - Different systems for habitual versus goal-directed control are thought to underlie human decision-making. Working memory is known to shape these decision-making systems and
their interplay, and is known to support goal-directed decision making even under stress. Here, we investigated if and how decision systems are differentially influenced by breaks filled with diverse everyday life activities known to modulate working memory performance. We used a within-subject design where young adults listened to music and played a video game during breaks interleaved with trials of a sequential two-step Markov decision task, designed to assess habitual as well as goal-directed decision making. Based on a neurocomputational model of task performance, we observed that for individuals with a rather limited
working memory capacity video gaming as compared to music reduced reliance on the goal-directed decision-making system, while a rather large working memory capacity prevented such a decline. Our findings suggest differential effects of everyday activities on key decision-making processes.
KW  - Decision making
KW  - Games
KW  - Working memory
KW  - Video games
KW  - Cognition
KW  - Cognitive impairment
KW  - Music cognition
KW  - Learning
Y1  - 2016
U6  - https://doi.org/10.1371/JOURNAL.PONE.0150165
SN  - 1932-6203
VL  - 11
IS  - 3
SP  - 1
EP  - 12
PB  - Public Library of Science
CY  - Lawrence, Kan.
ER  - 
TY  - JOUR
A1  - Sebold, Miriam Hannah
A1  - Garbusow, Maria
A1  - Jetzschmann, P.
A1  - Schad, Daniel
A1  - Nebe, S.
A1  - Schlagenhauf, Florian
A1  - Heinz, A.
A1  - Rapp, Michael Armin
A1  - Romanczuk-Seiferth, Nina
T1  - Reward and avoidance learning in the context of aversive environments and possible implications for depressive symptoms
JF  - Psychopharmacology
N2  - Background Aversive stimuli in the environment influence human actions. This includes valence-dependent influences on action selection, e.g., increased avoidance but decreased approach behavior. However, it is yet unclear how aversive stimuli interact with complex learning and decision-making in the reward and avoidance domain. Moreover, the underlying computational mechanisms of these decision-making biases are unknown. Methods To elucidate these mechanisms, 54 healthy young male subjects performed a two-step sequential decision-making task, which allows to computationally model different aspects of learning, e.g., model-free, habitual, and model-based, goal-directed learning. We used a within-subject design, crossing task valence (reward vs. punishment learning) with emotional context (aversive vs. neutral background stimuli). We analyzed choice data, applied a computational model, and performed simulations. Results Whereas model-based learning was not affected, aversive stimuli interacted with model-free learning in a way that depended on task valence. Thus, aversive stimuli increased model-free avoidance learning but decreased model-free reward learning. The computational model confirmed this effect: the parameter lambda that indicates the influence of reward prediction errors on decision values was increased in the punishment condition but decreased in the reward condition when aversive stimuli were present. Further, by using the inferred computational parameters to simulate choice data, our effects were captured. Exploratory analyses revealed that the observed biases were associated with subclinical depressive symptoms. Conclusion Our data show that aversive environmental stimuli affect complex learning and decision-making, which depends on task valence. Further, we provide a model of the underlying computations of this affective modulation. Finally, our finding of increased decision-making biases in subjects reporting subclinical depressive symptoms matches recent reports of amplified Pavlovian influences on action selection in depression and suggests a potential vulnerability factor for mood disorders. We discuss our findings in the light of the involvement of the neuromodulators serotonin and dopamine.
KW  - Reward learning
KW  - Avoidance learning
KW  - Reinforcement learning
KW  - Computational psychiatry
KW  - Decision-making
KW  - Affective modulation
KW  - Depression symptoms
Y1  - 2019
U6  - https://doi.org/10.1007/s00213-019-05299-9
SN  - 0033-3158
SN  - 1432-2072
VL  - 236
IS  - 8
SP  - 2437
EP  - 2449
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Stracke, A.
A1  - Bayer, A.
A1  - Zimmermann, S.
A1  - Wendorff, Joachim Heinz
A1  - Wirges, Werner
A1  - Bauer-Gogonea, Simona
A1  - Bauer, Siegfried
A1  - Gerhard, Reimund
T1  - Relaxation behaviour of electrically induced polar orientation and of optically induced non-polar orientation in an azo-chromophore side group polymer
Y1  - 1999
SN  - 0022-3727
ER  - 
TY  - JOUR
A1  - Sebold, Miriam Hannah
A1  - Spitta, G.
A1  - Gleich, T.
A1  - Dembler-Stamm, T.
A1  - Butler, Oisin
A1  - Zacharias, Kristin
A1  - Aydin, S.
A1  - Garbusow, Maria
A1  - Rapp, Michael Armin
A1  - Schubert, Florian
A1  - Buchert, Ralph
A1  - Gallinat, Jürgen
A1  - Heinz, A.
T1  - Stressful life events are associated with striatal dopamine receptor availability in alcohol dependence
JF  - Journal of neural transmission
N2  - Stress plays a key role in modulating addictive behavior and can cause relapse following periods of abstinence. Common effects of stress and alcohol on the dopaminergic system have been suggested, although the precise mechanisms are unclear. Here, we investigated 20 detoxified alcohol-dependent patients and 19 matched healthy controls and assessed striatal D2/D3 availability using [F-18]-fallypride positron emission tomography and stressful life events. We found a strong association between striatal D2/D3 availability and stress in patients, but not in healthy controls. Interestingly, we found increased D2/D3 receptor availability in patients with higher stress levels. This mirrors complex interactions between stress and alcohol intake in animal studies and emphasizes the importance to investigate stress exposure in neurobiological studies of addiction.
KW  - Stressful life events
KW  - Dopamine D2
KW  - D3 receptor
KW  - Positron emission tomography
KW  - Striatum
KW  - Alcohol dependence
Y1  - 2019
U6  - https://doi.org/10.1007/s00702-019-01985-2
SN  - 0300-9564
SN  - 1435-1463
VL  - 126
IS  - 9
SP  - 1127
EP  - 1134
PB  - Springer
CY  - Wien
ER  - 
TY  - JOUR
A1  - Heinz, Wolfgang S.
T1  - Maximilian Spohr, Der neue Menschenrechtsrat und das Hochkommissariat für Menschenrechte der Vereinten Nationen. Entstehung, Entwicklung und Zusammenarbeit [rezensiert von Wolfgang S. Heinz]
JF  - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen
N2  - Buchbesprechung:
Maximilian Spohr, Der neue Menschenrechtsrat und das Hochkommissariat für Menschenrechte
der Vereinten Nationen. Entstehung, Entwicklung und Zusammenarbeit, Duncker &
Humblot, 2014, 252 Seiten, ISBN 978-3-428-14236-1, 74,90 €.
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-84281
SN  - 1434-2820
VL  - 20
IS  - 1
SP  - 65
EP  - 66
ER  - 
TY  - CHAP
A1  - Baeriswyl, Pascale
A1  - Heinz, Wolfgang S.
A1  - Hüfner, Klaus
A1  - Martens, Jens
T1  - Konzepte für die Reform der Vereinten Nationen
BT  - 12. Potsdamer UNO-Konferenz am 28. Juni 2014
T2  - Potsdamer UNO-Konferenzen
N2  - Die zwölfte Konferenz des Forschungskreises Vereinte Nationen wurde am 28. Juni 2014 an der Universität Potsdam veranstaltet und stand unter dem Thema „Konzepte für die Reform der Vereinten Nationen“. Dabei wurde das komplexe Verhältnis zwischen Reformnotwendigkeit und Machbarkeits­erwartungen einerseits und ausgebliebenen weitreichenden Strukturreformen und erfolgten „kleineren“, pragmatischen Reformschritten andererseits deutlich. Mit den vier Referaten stellte die Konferenz in der Tradition der Potsdamer UNO-Konferenzen die Verbindung von Wissenschaft und Praxis unter Beteiligung unterschiedlicher Disziplinen her.
Mit der Broschüre soll allen Interessierten die Möglichkeit gegeben werden, Einblick in ausgewählte Schwerpunkte der Reformdiskussion zu erhalten: 
An ein Grundsatzreferat zu bisherigen Reformprozessen im UN-System ins­gesamt schließen sich drei Texte an, die das Verhältnis zwischen den Vereinten Nationen und den nichtstaatlichen Akteuren in den Blick nehmen, die relativ neue Institution des Menschenrechtsrates als Teil der Reform­bemühungen betrachten und schließlich Ergebnisse und Trends bei den Reformen der Arbeitsmethoden des Sicherheitsrates erörtern.
T3  - Potsdamer UNO-Konferenzen - 11 
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-78065
SN  - 978-3-86956-315-2
SN  - 1617-4704
IS  - 11
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Schad, Daniel
A1  - Garbusow, Maria
A1  - Friedel, Eva
A1  - Sommer, Christian
A1  - Sebold, Miriam Hannah
A1  - Hägele, Claudia
A1  - Bernhardt, Nadine
A1  - Nebe, Stephan
A1  - Kuitunen-Paul, Sören
A1  - Liu, Shuyan
A1  - Eichmann, Uta
A1  - Beck, Anne
A1  - Wittchen, Hans-Ulrich
A1  - Walter, Henrik
A1  - Sterzer, Philipp
A1  - Zimmermann, Ulrich S.
A1  - Smolka, Michael N.
A1  - Schlagenhauf, Florian
A1  - Huys, Quentin J. M.
A1  - Heinz, Andreas
A1  - Rapp, Michael Armin
T1  - Neural correlates of instrumental responding in the context of alcohol-related cues index disorder severity and relapse risk
JF  - European archives of psychiatry and clinical neuroscience : official organ of the German Society for Biological Psychiatry
N2  - The influence of Pavlovian conditioned stimuli on ongoing behavior may contribute to explaining how alcohol cues stimulate drug seeking and intake. Using a Pavlovian-instrumental transfer task, we investigated the effects of alcohol-related cues on approach behavior (i.e., instrumental response behavior) and its neural correlates, and related both to the relapse after detoxification in alcohol-dependent patients. Thirty-one recently detoxified alcohol-dependent patients and 24 healthy controls underwent instrumental training, where approach or non-approach towards initially neutral stimuli was reinforced by monetary incentives. Approach behavior was tested during extinction with either alcohol-related or neutral stimuli (as Pavlovian cues) presented in the background during functional magnetic resonance imaging (fMRI). Patients were subsequently followed up for 6 months. We observed that alcohol-related background stimuli inhibited the approach behavior in detoxified alcohol-dependent patients (t = -3.86, p < .001), but not in healthy controls (t = -0.92, p = .36). This behavioral inhibition was associated with neural activation in the nucleus accumbens (NAcc) (t((30)) = 2.06, p < .05). Interestingly, both the effects were only present in subsequent abstainers, but not relapsers and in those with mild but not severe dependence. Our data show that alcohol-related cues can acquire inhibitory behavioral features typical of aversive stimuli despite being accompanied by a stronger NAcc activation, suggesting salience attribution. The fact that these findings are restricted to abstinence and milder illness suggests that they may be potential resilience factors.
KW  - Alcohol dependence
KW  - Human neuroimaging
KW  - Nucleus accumbens
KW  - Pavlovian-instrumental transfer
KW  - Relapse
Y1  - 2018
U6  - https://doi.org/10.1007/s00406-017-0860-4
SN  - 0940-1334
SN  - 1433-8491
VL  - 269
IS  - 3
SP  - 295
EP  - 308
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Schad, Daniel
A1  - Juenger, Elisabeth
A1  - Sebold, Miriam Hannah
A1  - Garbusow, Maria
A1  - Bernhardt, Nadine
A1  - Javadi, Amir-Homayoun
A1  - Zimmermann, Ulrich S.
A1  - Smolka, Michael N.
A1  - Heinz, Andreas
A1  - Rapp, Michael Armin
A1  - Huys, Quentin J. M.
T1  - Processing speed enhances model-based over model-free reinforcement learning in the presence of high working memory functioning
JF  - Frontiers in psychology
N2  - Theories of decision-making and its neural substrates have long assumed the existence of two distinct and competing valuation systems, variously described as goal-directed vs. habitual, or, more recently and based on statistical arguments, as model-free vs. model-based reinforcement-learning. Though both have been shown to control choices, the cognitive abilities associated with these systems are under ongoing investigation. Here we examine the link to cognitive abilities, and find that individual differences in processing speed covary with a shift from model-free to model-based choice control in the presence of above-average working memory function. This suggests shared cognitive and neural processes; provides a bridge between literatures on intelligence and valuation; and may guide the development of process models of different valuation components. Furthermore, it provides a rationale for individual differences in the tendency to deploy valuation systems, which may be important for understanding the manifold neuropsychiatric diseases associated with malfunctions of valuation.
KW  - decision-making
KW  - reward
KW  - cognitive abilities
KW  - model-based and model-free learning
KW  - fluid intelligence
KW  - habitual and goal-directed system
Y1  - 2014
U6  - https://doi.org/10.3389/fpsyg.2014.01450
SN  - 1664-1078
VL  - 5
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Garbusow, Maria
A1  - Schad, Daniel
A1  - Sebold, Miriam Hannah
A1  - Friedel, Eva
A1  - Bernhardt, Nadine
A1  - Koch, Stefan P.
A1  - Steinacher, Bruno
A1  - Kathmann, Norbert
A1  - Geurts, Dirk E. M.
A1  - Sommer, Christian
A1  - Mueller, Dirk K.
A1  - Nebe, Stephan
A1  - Paul, Soeren
A1  - Wittchen, Hans-Ulrich
A1  - Zimmermann, Ulrich S.
A1  - Walter, Henrik
A1  - Smolka, Michael N.
A1  - Sterzer, Philipp
A1  - Rapp, Michael Armin
A1  - Huys, Quentin J. M.
A1  - Schlagenhauf, Florian
A1  - Heinz, Andreas
T1  - Pavlovian-to-instrumental transfer effects in the nucleus accumbens relate to relapse in alcohol dependence
JF  - Addiction biology
N2  - In detoxified alcohol-dependent patients, alcohol-related stimuli can promote relapse. However, to date, the mechanisms by which contextual stimuli promote relapse have not been elucidated in detail. One hypothesis is that such contextual stimuli directly stimulate the motivation to drink via associated brain regions like the ventral striatum and thus promote alcohol seeking, intake and relapse. Pavlovian-to-Instrumental-Transfer (PIT) may be one of those behavioral phenomena contributing to relapse, capturing how Pavlovian conditioned (contextual) cues determine instrumental behavior (e.g. alcohol seeking and intake). We used a PIT paradigm during functional magnetic resonance imaging to examine the effects of classically conditioned Pavlovian stimuli on instrumental choices in n=31 detoxified patients diagnosed with alcohol dependence and n=24 healthy controls matched for age and gender. Patients were followed up over a period of 3 months. We observed that (1) there was a significant behavioral PIT effect for all participants, which was significantly more pronounced in alcohol-dependent patients; (2) PIT was significantly associated with blood oxygen level-dependent (BOLD) signals in the nucleus accumbens (NAcc) in subsequent relapsers only; and (3) PIT-related NAcc activation was associated with, and predictive of, critical outcomes (amount of alcohol intake and relapse during a 3 months follow-up period) in alcohol-dependent patients. These observations show for the first time that PIT-related BOLD signals, as a measure of the influence of Pavlovian cues on instrumental behavior, predict alcohol intake and relapse in alcohol dependence.
KW  - human Pavlovian-to-instrumental transfer
KW  - nucleus accumbens
KW  - relapse in alcohol use disorder
Y1  - 2016
U6  - https://doi.org/10.1111/adb.12243
SN  - 1355-6215
SN  - 1369-1600
VL  - 21
SP  - 719
EP  - 731
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Sebold, Miriam Hannah
A1  - Nebe, Stephan
A1  - Garbusow, Maria
A1  - Guggenmos, Matthias
A1  - Schad, Daniel
A1  - Beck, Anne
A1  - Kuitunen-Paul, Sören
A1  - Sommer, Christian
A1  - Frank, Robin
A1  - Neu, Peter
A1  - Zimmermann, Ulrich S.
A1  - Rapp, Michael Armin
A1  - Smolka, Michael N.
A1  - Huys, Quentin J. M.
A1  - Schlagenhauf, Florian
A1  - Heinz, Andreas
T1  - When Habits Are Dangerous: Alcohol Expectancies and Habitual Decision Making Predict Relapse in Alcohol Dependence
JF  - Biological psychiatry : a journal of psychiatric neuroscience and therapeutics ; a publication of the Society of Biological Psychiatry
N2  - BACKGROUND: Addiction is supposedly characterized by a shift from goal-directed to habitual decision making, thus facilitating automatic drug intake. The two-step task allows distinguishing between these mechanisms by computationally modeling goal-directed and habitual behavior as model-based and model-free control. In addicted patients, decision making may also strongly depend upon drug-associated expectations. Therefore, we investigated model-based versus model-free decision making and its neural correlates as well as alcohol expectancies in alcohol-dependent patients and healthy controls and assessed treatment outcome in patients. METHODS: Ninety detoxified, medication-free, alcohol-dependent patients and 96 age-and gender-matched control subjects underwent functional magnetic resonance imaging during the two-step task. Alcohol expectancies were measured with the Alcohol Expectancy Questionnaire. Over a follow-up period of 48 weeks, 37 patients remained abstinent and 53 patients relapsed as indicated by the Alcohol Timeline Followback method. RESULTS: Patients who relapsed displayed reduced medial prefrontal cortex activation during model-based decision making. Furthermore, high alcohol expectancies were associated with low model-based control in relapsers, while the opposite was observed in abstainers and healthy control subjects. However, reduced model-based control per se was not associated with subsequent relapse. CONCLUSIONS: These findings suggest that poor treatment outcome in alcohol dependence does not simply result from a shift from model-based to model-free control but is instead dependent on the interaction between high drug expectancies and low model-based decision making. Reduced model-based medial prefrontal cortex signatures in those who relapse point to a neural correlate of relapse risk. These observations suggest that therapeutic interventions should target subjective alcohol expectancies.
KW  - Alcohol dependence
KW  - Alcohol expectancy
KW  - Goal-directed control
KW  - Medial prefrontal cortex
KW  - Reinforcement learning
KW  - Treatment outcome
Y1  - 2017
U6  - https://doi.org/10.1016/j.biopsych.2017.04.019
SN  - 0006-3223
SN  - 1873-2402
VL  - 82
SP  - 847
EP  - 856
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Sebold, Miriam Hannah
A1  - Schad, Daniel
A1  - Nebe, Stephan
A1  - Garbusow, Maria
A1  - Juenger, Elisabeth
A1  - Kroemer, Nils B.
A1  - Kathmann, Norbert
A1  - Zimmermann, Ulrich S.
A1  - Smolka, Michael N.
A1  - Rapp, Michael Armin
A1  - Heinz, Andreas
A1  - Huys, Quentin J. M.
T1  - Pavlovian-to-Instrumental Transfer Effects Rely Less on Model-based Reinforcement Learning
JF  - Journal of cognitive neuroscience
N2  - Behavioral choice can be characterized along two axes. One axis distinguishes reflexive, model-free systems that slowly accumulate values through experience and a model-based system that uses knowledge to reason prospectively. The second axis distinguishes Pavlovian valuation of stimuli from instrumental valuation of actions or stimulus–action pairs. This results in four values and many possible interactions between them, with important consequences for accounts of individual variation. We here explored whether individual variation along one axis was related to individual variation along the other. Specifically, we asked whether individuals' balance between model-based and model-free learning was related to their tendency to show Pavlovian interferences with instrumental decisions. In two independent samples with a total of 243 participants, Pavlovian–instrumental transfer effects were negatively correlated with the strength of model-based reasoning in a two-step task. This suggests a potential common underlying substrate predisposing individuals to both have strong Pavlovian interference and be less model-based and provides a framework within which to interpret the observation of both effects in addiction.
Y1  - 2016
U6  - https://doi.org/10.1162/jocn_a_00945
SN  - 0898-929X
SN  - 1530-8898
VL  - 28
SP  - 985
EP  - 995
PB  - MIT Press
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Haarhuis, Daniela
A1  - Heilinger, Jan-Christoph
A1  - Heinz, Wolfgang S.
A1  - Hofmann, Rainer
A1  - Marschelke, Jan-Christoph
A1  - Nägeler, Pascal
A1  - Schwarz, Alexander
A1  - von Ungern-Sternberg, Antje
A1  - Vasel, Johann Justus
T1  - MenschenRechtsMagazin : Informationen | Meinungen | Analysen
T2  - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen
N2  - Aus dem Inhalt: 

- 10 Jahre Responsibility to Protect: Ein Sieg für die Menschenrechte? – Eine politik- und rechtswissenschaftliche Analyse
- Neue Regeln zur Abwesenheit des Angeklagten vor dem IStGH:
Menschenrechtliche Anforderungen an In-absentia-Verfahren
- EGMR: S.A.S. ./. Frankreich – Urteilsbesprechung zum Burkaverbot
T3  - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen - 20.2015/1 
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-83299
SN  - 1434-2820
VL  - 20
IS  - 1
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - de Vera, Jean-Pierre Paul
A1  - Böttger, Ute
A1  - de la Torre Nötzel, Rosa
A1  - Sanchez, Francisco J.
A1  - Grunow, Dana
A1  - Schmitz, Nicole
A1  - Lange, Caroline
A1  - Hübers, Heinz-Wilhelm
A1  - Billi, Daniela
A1  - Baque, Mickael
A1  - Rettberg, Petra
A1  - Rabbow, Elke
A1  - Reitz, Günther
A1  - Berger, Thomas
A1  - Möller, Ralf
A1  - Bohmeier, Maria
A1  - Horneck, Gerda
A1  - Westall, Frances
A1  - Jänchen, Jochen
A1  - Fritz, Jörg
A1  - Meyer, Cornelia
A1  - Onofri, Silvano
A1  - Selbmann, Laura
A1  - Zucconi, Laura
A1  - Kozyrovska, Natalia
A1  - Leya, Thomas
A1  - Foing, Bernard
A1  - Demets, Rene
A1  - Cockell, Charles S.
A1  - Bryce, Casey
A1  - Wagner, Dirk
A1  - Serrano, Paloma
A1  - Edwards, Howell G. M.
A1  - Joshi, Jasmin Radha
A1  - Huwe, Björn
A1  - Ehrenfreund, Pascale
A1  - Elsaesser, Andreas
A1  - Ott, Sieglinde
A1  - Meessen, Joachim
A1  - Feyh, Nina
A1  - Szewzyk, Ulrich
A1  - Jaumann, Ralf
A1  - Spohn, Tilman
T1  - Supporting Mars exploration BIOMEX in Low Earth Orbit and further astrobiological studies on the Moon using Raman and PanCam technology
JF  - Planetary and space science
N2  - The Low Earth Orbit (LEO) experiment Biology and Mars Experiment (BIOMEX) is an interdisciplinary and international space research project selected by ESA. The experiment will be accommodated on the space exposure facility EXPOSE-R2 on the International Space Station (ISS) and is foreseen to be launched in 2013. The prime objective of BIOMEX is to measure to what extent biomolecules, such as pigments and cellular components, are resistant to and able to maintain their stability under space and Mars-like conditions. The results of BIOMEX will be relevant for space proven biosignature definition and for building a biosignature data base (e.g. the proposed creation of an international Raman library). The library will be highly relevant for future space missions such as the search for life on Mars. The secondary scientific objective is to analyze to what extent terrestrial extremophiles are able to survive in space and to determine which interactions between biological samples and selected minerals (including terrestrial, Moon- and Mars analogs) can be observed under space and Mars-like conditions. In this context, the Moon will be an additional platform for performing similar experiments with negligible magnetic shielding and higher solar and galactic irradiation compared to LEO. Using the Moon as an additional astrobiological exposure platform to complement ongoing astrobiological LEO investigations could thus enhance the chances of detecting organic traces of life on Mars. We present a lunar lander mission with two related objectives: a lunar lander equipped with Raman and PanCam instruments which can analyze the lunar surface and survey an astrobiological exposure platform. This dual use of testing mission technology together with geo- and astrobiological analyses will significantly increase the science return, and support the human preparation objectives. It will provide knowledge about the Moon's surface itself and, in addition, monitor the stability of life-markers, such as cells, cell components and pigments, in an extraterrestrial environment with much closer radiation properties to the surface of Mars. The combination of a Raman data base of these data together with data from LEO and space simulation experiments, will lead to further progress on the analysis and interpretation of data that we will obtain from future Moon and Mars exploration missions.
KW  - Moon
KW  - Mars
KW  - Low Earth Orbit
KW  - Astrobiology
KW  - Instrumentation
KW  - Spectroscopy
KW  - Biosignature
Y1  - 2012
U6  - https://doi.org/10.1016/j.pss.2012.06.010
SN  - 0032-0633
VL  - 74
IS  - 1
SP  - 103
EP  - 110
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Schulze-Makuch, Dirk
A1  - Wagner, Dirk
A1  - Kounaves, Samuel P.
A1  - Mangelsdorf, Kai
A1  - Devine, Kevin G.
A1  - de Vera, Jean-Pierre
A1  - Schmitt-Kopplin, Philippe
A1  - Grossart, Hans-Peter
A1  - Parro, Victor
A1  - Kaupenjohann, Martin
A1  - Galy, Albert
A1  - Schneider, Beate
A1  - Airo, Alessandro
A1  - Froesler, Jan
A1  - Davila, Alfonso F.
A1  - Arens, Felix L.
A1  - Caceres, Luis
A1  - Cornejo, Francisco Solis
A1  - Carrizo, Daniel
A1  - Dartnell, Lewis
A1  - DiRuggiero, Jocelyne
A1  - Flury, Markus
A1  - Ganzert, Lars
A1  - Gessner, Mark O.
A1  - Grathwohl, Peter
A1  - Guan, Lisa
A1  - Heinz, Jacob
A1  - Hess, Matthias
A1  - Keppler, Frank
A1  - Maus, Deborah
A1  - McKay, Christopher P.
A1  - Meckenstock, Rainer U.
A1  - Montgomery, Wren
A1  - Oberlin, Elizabeth A.
A1  - Probst, Alexander J.
A1  - Saenz, Johan S.
A1  - Sattler, Tobias
A1  - Schirmack, Janosch
A1  - Sephton, Mark A.
A1  - Schloter, Michael
A1  - Uhl, Jenny
A1  - Valenzuela, Bernardita
A1  - Vestergaard, Gisle
A1  - Woermer, Lars
A1  - Zamorano, Pedro
T1  - Transitory microbial habitat in the hyperarid Atacama Desert
JF  - Proceedings of the National Academy of Sciences of the United States of America
KW  - habitat
KW  - aridity
KW  - microbial activity
KW  - biomarker
KW  - Mars
Y1  - 2018
U6  - https://doi.org/10.1073/pnas.1714341115
SN  - 0027-8424
VL  - 115
IS  - 11
SP  - 2670
EP  - 2675
PB  - National Acad. of Sciences
CY  - Washington
ER  - 
TY  - JOUR
A1  - Sianova, D.
A1  - Zen, Achmad
A1  - Nothofer, Heinz-Georg
A1  - Asawapirom, Udom
A1  - Scherf, Ullrich
A1  - Hagen, R.
A1  - Bieringer, Thomas
A1  - Kostromine, S.
A1  - Neher, Dieter
T1  - Photoaddressable alignment layers for fluorescent polymers in polarized electroluminescence devices
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Oda, Masao
A1  - Nothofer, Heinz-Georg
A1  - Lieser, G.
A1  - Scherf, Ullrich
A1  - Meskers, S. C. J.
A1  - Neher, Dieter
T1  - Circularly-polarized electroluminescence from liquid-crystalline chiral polyfluorenes
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Oda, Masao
A1  - Meskers, S. C. J.
A1  - Nothofer, Heinz-Georg
A1  - Scherf, Ullrich
A1  - Neher, Dieter
T1  - Chiroptical properties of chiral-substituted polyfluorenes
Y1  - 2000
ER  -