TY - JOUR A1 - Schulze, Patricia S. C. A1 - Bett, Alexander J. A1 - Bivour, Martin A1 - Caprioglio, Pietro A1 - Gerspacher, Fabian M. A1 - Kabaklı, Özde Ş. A1 - Richter, Armin A1 - Stolterfoht, Martin A1 - Zhang, Qinxin A1 - Neher, Dieter A1 - Hermle, Martin A1 - Hillebrecht, Harald A1 - Glunz, Stefan W. A1 - Goldschmidt, Jan Christoph T1 - 25.1% high-efficiency monolithic perovskite silicon tandem solar cell with a high bandgap perovskite absorber JF - Solar RRL N2 - Monolithic perovskite silicon tandem solar cells can overcome the theoretical efficiency limit of silicon solar cells. This requires an optimum bandgap, high quantum efficiency, and high stability of the perovskite. Herein, a silicon heterojunction bottom cell is combined with a perovskite top cell, with an optimum bandgap of 1.68 eV in planar p-i-n tandem configuration. A methylammonium-free FA(0.75)Cs(0.25)Pb(I0.8Br0.2)(3) perovskite with high Cs content is investigated for improved stability. A 10% molarity increase to 1.1 m of the perovskite precursor solution results in approximate to 75 nm thicker absorber layers and 0.7 mA cm(-2) higher short-circuit current density. With the optimized absorber, tandem devices reach a high fill factor of 80% and up to 25.1% certified efficiency. The unencapsulated tandem device shows an efficiency improvement of 2.3% (absolute) over 5 months, showing the robustness of the absorber against degradation. Moreover, a photoluminescence quantum yield analysis reveals that with adapted charge transport materials and surface passivation, along with improved antireflection measures, the high bandgap perovskite absorber has the potential for 30% tandem efficiency in the near future. KW - heterojunction silicon solar cells KW - interfaces KW - perovskite solar cells KW - tandem solar cells KW - thin films Y1 - 2020 VL - 4 IS - 7 PB - John Wiley & Sons, Inc. CY - New Jersey ER - TY - JOUR A1 - Vaid, Akhil A1 - Somani, Sulaiman A1 - Russak, Adam J. A1 - De Freitas, Jessica K. A1 - Chaudhry, Fayzan F. A1 - Paranjpe, Ishan A1 - Johnson, Kipp W. A1 - Lee, Samuel J. A1 - Miotto, Riccardo A1 - Richter, Felix A1 - Zhao, Shan A1 - Beckmann, Noam D. A1 - Naik, Nidhi A1 - Kia, Arash A1 - Timsina, Prem A1 - Lala, Anuradha A1 - Paranjpe, Manish A1 - Golden, Eddye A1 - Danieletto, Matteo A1 - Singh, Manbir A1 - Meyer, Dara A1 - O'Reilly, Paul F. A1 - Huckins, Laura A1 - Kovatch, Patricia A1 - Finkelstein, Joseph A1 - Freeman, Robert M. A1 - Argulian, Edgar A1 - Kasarskis, Andrew A1 - Percha, Bethany A1 - Aberg, Judith A. A1 - Bagiella, Emilia A1 - Horowitz, Carol R. A1 - Murphy, Barbara A1 - Nestler, Eric J. A1 - Schadt, Eric E. A1 - Cho, Judy H. A1 - Cordon-Cardo, Carlos A1 - Fuster, Valentin A1 - Charney, Dennis S. A1 - Reich, David L. A1 - Böttinger, Erwin A1 - Levin, Matthew A. A1 - Narula, Jagat A1 - Fayad, Zahi A. A1 - Just, Allan C. A1 - Charney, Alexander W. A1 - Nadkarni, Girish N. A1 - Glicksberg, Benjamin S. T1 - Machine learning to predict mortality and critical events in a cohort of patients with COVID-19 in New York City: model development and validation JF - Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR N2 - Background: COVID-19 has infected millions of people worldwide and is responsible for several hundred thousand fatalities. The COVID-19 pandemic has necessitated thoughtful resource allocation and early identification of high-risk patients. However, effective methods to meet these needs are lacking. Objective: The aims of this study were to analyze the electronic health records (EHRs) of patients who tested positive for COVID-19 and were admitted to hospitals in the Mount Sinai Health System in New York City; to develop machine learning models for making predictions about the hospital course of the patients over clinically meaningful time horizons based on patient characteristics at admission; and to assess the performance of these models at multiple hospitals and time points. Methods: We used Extreme Gradient Boosting (XGBoost) and baseline comparator models to predict in-hospital mortality and critical events at time windows of 3, 5, 7, and 10 days from admission. Our study population included harmonized EHR data from five hospitals in New York City for 4098 COVID-19-positive patients admitted from March 15 to May 22, 2020. The models were first trained on patients from a single hospital (n=1514) before or on May 1, externally validated on patients from four other hospitals (n=2201) before or on May 1, and prospectively validated on all patients after May 1 (n=383). Finally, we established model interpretability to identify and rank variables that drive model predictions. Results: Upon cross-validation, the XGBoost classifier outperformed baseline models, with an area under the receiver operating characteristic curve (AUC-ROC) for mortality of 0.89 at 3 days, 0.85 at 5 and 7 days, and 0.84 at 10 days. XGBoost also performed well for critical event prediction, with an AUC-ROC of 0.80 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. In external validation, XGBoost achieved an AUC-ROC of 0.88 at 3 days, 0.86 at 5 days, 0.86 at 7 days, and 0.84 at 10 days for mortality prediction. Similarly, the unimputed XGBoost model achieved an AUC-ROC of 0.78 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. Trends in performance on prospective validation sets were similar. At 7 days, acute kidney injury on admission, elevated LDH, tachypnea, and hyperglycemia were the strongest drivers of critical event prediction, while higher age, anion gap, and C-reactive protein were the strongest drivers of mortality prediction. Conclusions: We externally and prospectively trained and validated machine learning models for mortality and critical events for patients with COVID-19 at different time horizons. These models identified at-risk patients and uncovered underlying relationships that predicted outcomes. KW - machine learning KW - COVID-19 KW - electronic health record KW - TRIPOD KW - clinical KW - informatics KW - prediction KW - mortality KW - EHR KW - cohort KW - hospital KW - performance Y1 - 2020 U6 - https://doi.org/10.2196/24018 SN - 1439-4456 SN - 1438-8871 VL - 22 IS - 11 PB - Healthcare World CY - Richmond, Va. ER - TY - GEN A1 - Kaastra, Jelle S. A1 - Paerels, Frits B.S. A1 - Durret, Florence A1 - Schindler, Sabine A1 - Richter, Philipp T1 - Thermal radiation processes T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - We discuss the different physical processes that are important to understand the thermal X-ray emission and absorption spectra of the diffuse gas in clusters of galaxies and the warm-hot intergalactic medium. The ionisation balance, line and continuum emission and absorption properties are reviewed and several practical examples are given that illustrate the most important diagnostic features in the X-ray spectra. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 891 KW - atomic processes KW - radiation mechanisms: thermal KW - intergalactic medium KW - X-rays: general Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-436220 SN - 1866-8372 IS - 891 SP - 155 EP - 190 ER - TY - JOUR A1 - Fox, Andrew J. A1 - Richter, Philipp A1 - Ashley, Trisha A1 - Heckman, Timothy M. A1 - Lehner, Nicolas A1 - Werk, Jessica K. A1 - Bordoloi, Rongmon A1 - Peeples, Molly S. T1 - The Mass Inflow and Outflow Rates of the Milky Way JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We present new calculations of the mass inflow and outflow rates around the Milky Way (MW), derived from a catalog of ultraviolet metal-line high-velocity clouds (HVCs). These calculations are conducted by transforming the HVC velocities into the Galactic standard of rest (GSR) reference frame, identifying inflowing (vGSR.<.0 km s(-1)) and outflowing (vGSR > 0 km s(-1)) populations, and using observational constraints on the distance, metallicity, dust content, covering fractions, and total silicon column density of each population. After removing HVCs associated with the Magellanic Stream and the Fermi Bubbles, we find inflow and outflow rates in cool (T similar to 10(4) K) ionized gas of dM(in)/dt greater than or similar to.(0.53 +/- 0.23)(d/12 kpc)(Z/0.2Z(circle dot))-1M(circle dot) yr(-1) and dM(out)/dt greater than or similar to (0.16 +/- 0.07)(d/12 kpc)(Z/0.5Z(circle dot))M--1(circle dot) yr(-1). The apparent excess of inflowing over outflowing gas suggests that the MW is currently in an inflow-dominated phase, but the presence of substantial mass flux in both directions supports a Galactic fountain model, in which gas is constantly recycled between the disk and the halo. We also find that the metal flux in both directions (in and out) is indistinguishable. By comparing the outflow rate to the Galactic star formation rate, we present the first estimate of the mass loading factor (eta(HVC)) of the disk-wide MW wind, finding eta(HVC) greater than or similar to (0.10 +/- 0.06)(d/12 kpc)(Z/0.5Z(circle dot))(-1). Including the contributions from low- and intermediatevelocity clouds and from hot gas would increase these inflow and outflow estimates. Y1 - 2019 U6 - https://doi.org/10.3847/1538-4357/ab40ad SN - 0004-637X SN - 1538-4357 VL - 884 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Richter, Philipp A1 - de Boer, Klaas S. A1 - Werner, Klaus A1 - Rauch, Thomas T1 - High-velocity gas toward the LMC resides in the Milky Way halo JF - Astronomy and astrophysics : an international weekly journal N2 - Aims. To explore the origin of high-velocity gas in the direction of the Large Magellanic Cloud, (LMC) we analyze absorption lines in the ultraviolet spectrum of a Galactic halo star that is located in front of the LMC at d = 9.2(-7.2)(+4.1) kpc distance. Methods. We study the velocity-component structure of low and intermediate metal ions (CII, SiII, SiIII) in the spectrum of RXJ0439.8-6809, as obtained with the Cosmic Origins Spectrograph (COS) onboard the Hubble Space Telescope (HST), and measure equivalent widths and column densities for these ions. We supplement our COS data with a Far-Ultraviolet Spectroscopic Explorer (FUSE) spectrum of the nearby LMC star Sk-69 59 and with Hi 21 cm data from the Leiden-Argentina-Bonn (LAB) survey. Results. Metal absorption toward RXJ0439.8-6809 is unambiguously detected in three different velocity components near v(LSR) = 0, + 60, and + 150 km s(-1). The presence of absorption proves that all three gas components are situated in front of the star, thus located in the disk and inner halo of the Milky Way. For the high-velocity cloud (HVC) at v(LSR) = + 150 km s(-1), we derive an oxygen abundance of [O/H] = -0.63 (similar to 0.2 solar) from the neighboring Sk-69 59 sight line, in accordance with previous abundance measurements for this HVC. From the observed kinematics we infer that the HVC hardly participates in the Galactic rotation. Conclusions. Our study shows that the HVC toward the LMC represents a Milky Way halo cloud that traces low column density gas with relatively low metallicity. We rule out scenarios in which the HVC represents material close to the LMC that stems from a LMC outflow. KW - Galaxy: halo KW - Galaxy: evolution KW - ISM: abundances KW - ISM: structure Y1 - 2015 U6 - https://doi.org/10.1051/0004-6361/201527451 SN - 1432-0746 VL - 584 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Esser, Günter A1 - Freyberger, H. J. A1 - Hoffmann, S. O. A1 - Hoyer, J. A1 - Richter, R. A1 - Harfst, T. T1 - Anpassung der Psychotherapie-Richtlinien zur Zulassung psychotherapeutischer Verfahren und Methoden Y1 - 2006 ER - TY - JOUR A1 - Richter, Martin A1 - Doupnik, Timothy S. T1 - The impact of culture on the interpretation of "in context" verbal probability expressions N2 - We report in this paper, the results of an investigation of the effect of national culture on the interpretation of "in context" verbal probability expressions. We develop hypotheses with regard to the effect that the interaction of the accounting value of conservatism and the context in which probability expressions are used will have on accountants' interpretations of those expressions. We elicit information from U.S. and German professional accountants to test three hypotheses. We find significant differences between U.S. and German accountants in the interpretation of several verbal probability expressions. In most cases, the German accountants are more conservative; for ... Y1 - 2004 SN - 1542-6297 ER - TY - JOUR A1 - Richter, Martin A1 - Doupnik, Timothy S. T1 - Interpretation of uncertainty expressions : a cross-national study N2 - This study investigates the effect of language-culture and linguistic translation on the interpretation of verbal uncertainty expressions found in International Accounting Standards. Data are collected from US Certified Public Accountants and German-speaking Wirtschaftsprüfer (chartered or certified accountants) to test three hypotheses. One group of German speakers evaluated uncertainty terms expressed in German and another group in English. The results indicate significant differences in interpretation across the three groups. Some differences are attributed to a language-culture effect and others to a translation effect, with the language-culture effect being more pervasive. These results raise the question of whether International Accounting Standards can be applied consistently across language- cultures. Y1 - 2003 ER - TY - JOUR A1 - Muzahid, S. A1 - Fonseca, G. A1 - Roberts, A. A1 - Rosenwasser, B. A1 - Richter, Philipp A1 - Narayanan, A. A1 - Churchill, C. A1 - Charlton, J. T1 - COS-Weak: probing the CGM using analogues of weak Mg II absorbers at z < 0.3 JF - Monthly notices of the Royal Astronomical Society N2 - We present a sample of 34 weak metal line absorbers at z < 0.3 selected by the simultaneous >3σ detections of the Si iiλ1260 and C iiλ1334 absorption lines, with Wr(SiII)<0.2 Å and Wr(CII)<0.3 Å, in archival HST/COS spectra. Our sample increases the number of known low-z ‘weak absorbers’ by a factor of >5. The column densities of H i and low-ionization metal lines obtained from Voigt profile fitting are used to build simple photoionization models. The inferred densities and line-of-sight thicknesses of the absorbers are in the ranges of −3.3 < log nH/cm−3 < −2.4 and ∼1 pc–50 kpc (median ≈500 pc), respectively. Most importantly, 85 per cent (50 per cent) of these absorbers show a metallicity of [Si/H]>−1.0(0.0)⁠. The fraction of systems showing near-/supersolar metallicity in our sample is significantly higher than in the H i-selected sample of Wotta et al., and the galaxy-selected sample of Prochaska et al., of absorbers probing the circum-galactic medium at similar redshift. A search for galaxies has revealed a significant galaxy-overdensity around these weak absorbers compared to random positions with a median impact parameter of 166 kpc from the nearest galaxy. Moreover, we find the presence of multiple galaxies in ≈80 per cent of the cases, suggesting group environments. The observed dN/dz of 0.8 ± 0.2 indicates that such metal-enriched, compact, dense structures are ubiquitous in the haloes of low-z group galaxies. We suggest that these are transient structures that are related to galactic outflows and/or stripping of metal-rich gas from galaxies. KW - galaxies: formation KW - galaxies: haloes KW - quasar: absorption line Y1 - 2018 U6 - https://doi.org/10.1093/mnras/sty529 SN - 0035-8711 SN - 1365-2966 VL - 476 IS - 4 SP - 4965 EP - 4986 PB - Oxford Univ. Press CY - Oxford ER - TY - CHAP A1 - Richter, M. A1 - Fairhall, Emma A. A1 - Hoffmann, S. A. A1 - Frühwald, J. A1 - Wright, Matthew C. A1 - Zeilinger, Katrin T1 - Dexamethasone induced hepatic differentiation of rat pancreatic progenitor cells (B-13) in a 3D multicompartment bioreactor system T2 - Journal of hepatology Y1 - 2013 SN - 0168-8278 VL - 58 IS - 1 SP - S416 EP - S416 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Murray, Claire E. A1 - Stanimirovic, Snezana A1 - McClure-Griffiths, Naomi M. A1 - Putman, Mary E. A1 - Liszt, Harvey S. A1 - Wong, Tony A1 - Richter, Philipp A1 - Dawson, Joanne R. A1 - Dickey, John M. A1 - Lindner, Robert R. A1 - Babler, Brian L. A1 - Allison, James R. T1 - First detection of HCO+ absorption in the magellanic system JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We present the first detection of HCO+ absorption in the Magellanic System. Using the ATCA, we observed nine extragalactic radio continuum sources behind the Magellanic System and detected HCO+ absorption toward one source located behind the leading edge of the Magellanic Bridge. The detection is located at an LSR velocity of v = 214.0 +/- 0.4 km s(-1), with an FWHM of Delta v = 4.5 +/- 1.0 km s(-1), and an optical depth of tau (HCO+) = 0.10 +/- 0.02. Although there is abundant neutral hydrogen (H I) surrounding the sight line in position-velocity space, at the exact location of the absorber the H I column density is low, <10(20) cm(-2), and there is little evidence for dust or CO emission from Planck observations. While the origin and survival of molecules in such a diffuse environment remain unclear, dynamical events such as H I flows and cloud collisions in this interacting system likely play an important role. KW - ISM: molecules KW - ISM: structure KW - Magellanic Clouds Y1 - 2015 U6 - https://doi.org/10.1088/0004-637X/808/1/41 SN - 0004-637X SN - 1538-4357 VL - 808 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - BOOK A1 - Doupnik, Timothy S. A1 - Richter, Martin T1 - Interpretation of uncertainty expressions : a cross-national study T3 - Studies in Auditing : Beiträge zur betriebswirtschaftlichen Prüfungslehre Y1 - 2000 SN - 1433-9394 VL - 2 PB - Univ. CY - Potsdam ER - TY - JOUR A1 - Wisotzki, Lutz A1 - Bacon, R. A1 - Brinchmann, J. A1 - Cantalupo, S. A1 - Richter, Philipp A1 - Schaye, J. A1 - Schmidt, Kasper Borello A1 - Urrutia, Tanya A1 - Weilbacher, Peter Michael A1 - Akhlaghi, M. A1 - Bouche, N. A1 - Contini, T. A1 - Guiderdoni, B. A1 - Herenz, E. C. A1 - Inami, H. A1 - Kerutt, Josephine Victoria A1 - Leclercq, F. A1 - Marino, R. A. A1 - Maseda, M. A1 - Monreal-Ibero, A. A1 - Nanayakkara, T. A1 - Richard, J. A1 - Saust, R. A1 - Steinmetz, Matthias A1 - Wendt, Martin T1 - Nearly all the sky is covered by Lyman-alpha emission around high-redshift galaxies JF - Nature : the international weekly journal of science N2 - Galaxies are surrounded by large reservoirs of gas, mostly hydrogen, that are fed by inflows from the intergalactic medium and by outflows from galactic winds. Absorption-line measurements along the lines of sight to bright and rare background quasars indicate that this circumgalactic medium extends far beyond the starlight seen in galaxies, but very little is known about its spatial distribution. The Lyman-alpha transition of atomic hydrogen at a wavelength of 121.6 nanometres is an important tracer of warm (about 104 kelvin) gas in and around galaxies, especially at cosmological redshifts greater than about 1.6 at which the spectral line becomes observable from the ground. Tracing cosmic hydrogen through its Lyman-a emission has been a long-standing goal of observational astrophysics(1-3), but the extremely low surface brightness of the spatially extended emission is a formidable obstacle. A new window into circumgalactic environments was recently opened by the discovery of ubiquitous extended Lyman-alpha emission from hydrogen around high-redshift galaxies(4,5). Such measurements were previously limited to especially favourable systems(6-8) or to the use of massive statistical averaging(9,10) because of the faintness of this emission. Here we report observations of low-surface-brightness Lyman-alpha emission surrounding faint galaxies at redshifts between 3 and 6. We find that the projected sky coverage approaches 100 per cent. The corresponding rate of incidence (the mean number of Lyman-alpha emitters penetrated by any arbitrary line of sight) is well above unity and similar to the incidence rate of high-column-density absorbers frequently detected in the spectra of distant quasars(11-14). This similarity suggests that most circumgalactic atomic hydrogen at these redshifts has now been detected in emission. Y1 - 2018 U6 - https://doi.org/10.1038/s41586-018-0564-6 SN - 0028-0836 SN - 1476-4687 VL - 562 IS - 7726 SP - 229 EP - 232 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Richter, Philipp A1 - Fox, Andrew J. A1 - Ben Bekhti, Nadya A1 - Murphy, M. T. A1 - Bomans, Dominik J. A1 - Frank, S. T1 - High-resolution absorption spectroscopy of the circumgalactic medium of the Milky Way JF - Astronomische Nachrichten = Astronomical notes KW - Galaxy: halo KW - Galaxy: structure KW - quasars: absorption lines KW - techniques: spectroscopic Y1 - 2014 U6 - https://doi.org/10.1002/asna.201312013 SN - 0004-6337 SN - 1521-3994 VL - 335 IS - 1 SP - 92 EP - 98 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Sigel, Keith Magnus A1 - Swartz, Talia H. A1 - Golden, Eddye A1 - Paranjpe, Ishan A1 - Somani, Sulaiman A1 - Richter, Felix A1 - De Freitas, Jessica K. A1 - Miotto, Riccardo A1 - Zhao, Shan A1 - Polak, Paz A1 - Mutetwa, Tinaye A1 - Factor, Stephanie A1 - Mehandru, Saurabh A1 - Mullen, Michael A1 - Cossarini, Francesca A1 - Böttinger, Erwin A1 - Fayad, Zahi A1 - Merad, Miriam A1 - Gnjatic, Sacha A1 - Aberg, Judith A1 - Charney, Alexander A1 - Nadkarni, Girish A1 - Glicksberg, Benjamin S. T1 - Coronavirus 2019 and people living with human immunodeficiency virus BT - outcomes for hospitalized patients in New York City JF - Clinical infectious diseases : electronic edition N2 - Background: There are limited data regarding the clinical impact of coronavirus disease 2019 (COVID-19) on people living with human immunodeficiency virus (PLWH). In this study, we compared outcomes for PLWH with COVID-19 to a matched comparison group. Methods: We identified 88 PLWH hospitalized with laboratory-confirmed COVID-19 in our hospital system in New York City between 12 March and 23 April 2020. We collected data on baseline clinical characteristics, laboratory values, HIV status, treatment, and outcomes from this group and matched comparators (1 PLWH to up to 5 patients by age, sex, race/ethnicity, and calendar week of infection). We compared clinical characteristics and outcomes (death, mechanical ventilation, hospital discharge) for these groups, as well as cumulative incidence of death by HIV status. Results: Patients did not differ significantly by HIV status by age, sex, or race/ethnicity due to the matching algorithm. PLWH hospitalized with COVID-19 had high proportions of HIV virologic control on antiretroviral therapy. PLWH had greater proportions of smoking (P < .001) and comorbid illness than uninfected comparators. There was no difference in COVID-19 severity on admission by HIV status (P = .15). Poor outcomes for hospitalized PLWH were frequent but similar to proportions in comparators; 18% required mechanical ventilation and 21% died during follow-up (compared with 23% and 20%, respectively). There was similar cumulative incidence of death over time by HIV status (P = .94). Conclusions: We found no differences in adverse outcomes associated with HIV infection for hospitalized COVID-19 patients compared with a demographically similar patient group. KW - human immunodeficiency virus KW - coronavirus 2019 KW - severe acute respiratory KW - syndrome coronavirus 2 Y1 - 2020 U6 - https://doi.org/10.1093/cid/ciaa880 SN - 1058-4838 SN - 1537-6591 VL - 71 IS - 11 SP - 2933 EP - 2938 PB - Oxford Univ. Press CY - Cary, NC ER -