TY - GEN A1 - Erra, Ramon Guevara A1 - Velazquez, Jose L. Perez A1 - Rosenblum, Michael T1 - Neural Synchronization from the Perspective of Non-linear Dynamics T2 - Frontiers in computational neuroscience / Frontiers Research Foundation KW - brain synchronization KW - non-linear dynamics KW - neural synchonization KW - brain rhythms KW - epilepsy Y1 - 2017 U6 - https://doi.org/10.3389/fncom.2017.00098 SN - 1662-5188 VL - 11 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Perez-Velazquez, Jose Luis A1 - Erra, Ramon Guevara A1 - Rosenblum, Michael T1 - The Epileptic Thalamocortical Network is a Macroscopic Self-Sustained Oscillator: Evidence from Frequency-Locking Experiments in Rat Brains JF - Scientific reports N2 - The rhythmic activity observed in nervous systems, in particular in epilepsies and Parkinson's disease, has often been hypothesized to originate from a macroscopic self-sustained neural oscillator. However, this assumption has not been tested experimentally. Here we support this viewpoint with in vivo experiments in a rodent model of absence seizures, by demonstrating frequency locking to external periodic stimuli and finding the characteristic Arnold tongue. This result has important consequences for developing methods for the control of brain activity, such as seizure cancellation. Y1 - 2015 U6 - https://doi.org/10.1038/srep08423 SN - 2045-2322 VL - 5 PB - Nature Publ. Group CY - London ER -