TY  - JOUR
A1  - Cywinski, Piotr J.
A1  - Idzik, Krzysztof R.
A1  - Cranfield, Charles G.
A1  - Beckert, Rainer
A1  - Mohr, Gerhard J.
T1  - Synthesis and sensing properties of a new carbazole fluorosensor for detection of abacavir
N2  - An abacavir-targeted fluorosensor based on the carbazole moiety has been synthesised and characterised. Recognition of abacavir is by base pairing between a uracil moiety present in the fluorosensor and the guanine moiety of abacavir. The fluorosensor exhibits five-fold quenching in the presence of 50M abacavir. Its sensitivity to abacavir is superior to that of other reverse transcriptase inhibitors: zidovudine, lamivudine and didanosine. Due to its high sensitivity, this fluorosensor has the potential to be used in multi-analyte array-based detection platforms as well as in microfluidics systems.
Y1  - 2010
UR  - http://www.informaworld.com/openurl?genre=journal&issn=1061-0278
U6  - https://doi.org/10.1080/10610278.2010.506541
SN  - 1061-0278
ER  -