TY - JOUR A1 - Hoffmann, Michael A1 - Hoffmann, Petra T1 - 'Zielgerichtetheit' und 'Zweckbestimmtheit' in der Außenperspektive : ein Rückblick auf "Deutsch als Fremdsprache" in China Y1 - 1997 ER - TY - JOUR A1 - Hoffmann, Svenja Sarah Helen A1 - Cortes-Garcia, Laura A1 - Warschburger, Petra T1 - Weight/shape and muscularity concerns and emotional problems in adolescent boys and girls BT - A cross-lagged panel analysis JF - Journal of adolescence N2 - Introduction: The goal of the present study was to identify the prospective relations between weight/shape and muscularity concerns and emotional problems in adolescents. Methods: Self-report data of 966 German male and female adolescents were analyzed in a cross lagged panel design. Results: Analyses of latent means revealed significant correlations between weight/shape concern and emotional problems as well as between muscularity concern and emotional problems in both genders. Moreover, weight/shape concern predicted emotional problems prospectively, but only in girls. Regarding muscularity concern, we could not find any prospective relation with emotional problems In boys or girls from the general population. Conclusions: It is assumed that as appearance is highly relevant for the self-concept in girls, concerns about the look might promote emotional problems. Thus, weight/shape concern should be addressed in the prevention of emotional problems in adolescent girls, whereas further research is necessary investigating the contribution of muscularity concern in this context. KW - Weight/shape concern KW - Muscularity concern KW - Depressive symptoms KW - Adolescents KW - Cross-lagged panel analysis Y1 - 2018 U6 - https://doi.org/10.1016/j.adolescence.2018.07.005 SN - 0140-1971 SN - 1095-9254 VL - 68 SP - 70 EP - 77 PB - Elsevier CY - London ER - TY - JOUR A1 - Cortes-Garcia, Laura A1 - Hoffmann, Svenja A1 - Warschburger, Petra A1 - Senra, Carmen T1 - Exploring the reciprocal relationships between adolescents' perceptions of parental and peer attachment and disordered eating BT - a multiwave cross-lagged panel analysis JF - International Journal of eating disorders N2 - Objective This prospective study explored bidirectional associations between attachment quality towards mother, father, and peers and disordered eating among a large population-based sample of boys and girls in the transition from preadolescence to adolescence. Specifically, we examined whether insecure attachment relationships emerged as a risk factor for or as an outcome of disordered eating. Method A population-based sample of 904 adolescent girls and boys was assessed four times, at baseline (T1; M-age = 10.8 years) and at 2-, 4-, and 6-year follow-up (T2, T3, and T4). Prospective data were analyzed using cross-lagged panel models for each attachment figure (i.e., mother, father, peers) in a multigroup design to compare genders. Results Better attachment to the mother led to less pronounced disturbed eating in girls across the entire age range and in boys across two time periods. In girls, more pronounced disordered eating at T3 predicted worse attachment to the mother at T4 and better attachment to the father at T1 predicted less disturbed eating at T2. In boys, disordered eating at T1 predicted better attachment to the father at T2. Concerning peer attachment, better attachment at T1 predicted disordered eating at T2, in boys only. No other significant cross-lagged effects emerged. Discussion These findings highlight the differential and gender-specific contribution of attachment figures to the development of disordered eating in adolescence. Programs aimed at improving communication and trust in the relationship with parents might be promising in the prevention of disordered eating and the subsequent deterioration of parent-child attachment relationships. KW - adolescents KW - attachment KW - cross-lagged panel analysis KW - disordered eating KW - gender Y1 - 2019 U6 - https://doi.org/10.1002/eat.23086 SN - 0276-3478 SN - 1098-108X VL - 52 IS - 8 SP - 924 EP - 934 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Hoffmann, Svenja A1 - Warschburger, Petra T1 - Patterns of body image concerns in adolescence and early adulthood BT - a latent profile analysis JF - Eating Behaviors N2 - The present study aimed at identifying latent profiles of body image concerns in adolescents and young adults. Subsequently, associations between these profiles and potentially harmful behaviors are examined. Self-report data of 758 male and female adolescents, aged 14 to 22 years, were analyzed. Participants provided demographic and anthropometric data and completed surveys on weight/shape and muscularity concern as well as on disturbed eating behaviors and dysfunctional exercise. Latent profile analyses of weight/shape concern and muscularity concern were performed separately for each gender. The analyses indicated three-class solutions in men and women. In both genders, the inconspicuous class, characterized by small amounts of weight/shape and muscularity concerns, was the largest one (86% in men, 68% in women). Whereas 10% of the men and 23% of the women were assigned to the borderline class, 4% of the men and 8% of the women formed the conspicuous class (marked weight/shape and muscularity concerns). Between genders, the degrees of muscularity concern differed in the borderline and inconspicuous classes, while the degrees of weight/shape concern differed in the inconspicuous class only. The comparable degrees of weight/shape and muscularity concerns in men and women in the affected classes underline the relevance of both aspects in both genders. Classes could be distinguished by harmful behaviors, like restrained eating or emotional exercise, proving the clinical significance of body image concerns. KW - Weight concern KW - Shape concern KW - Muscularity concern KW - Adolescent KW - Young adult KW - Latent profile analysis Y1 - 2018 U6 - https://doi.org/10.1016/j.eatbeh.2018.02.002 SN - 1471-0153 SN - 1873-7358 VL - 29 SP - 28 EP - 34 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hoffmann, Petra T1 - Die Chance nutzen : ein Vorwort Y1 - 2004 SN - 1432-8208 ER - TY - JOUR A1 - Hoffmann, Petra T1 - Studienkollegs und ihr Beitrag zum Studienerfolg : ein Vorwort Y1 - 2005 SN - 1432-8208 ER - TY - JOUR A1 - Lombino, Meinolf A1 - Hoffmann, Petra T1 - Der Wirtschaftsstandort Berlin-Brandenburg vor dem Hintergrund der EU-Osterweiterung : Projektarbeit im W-Kurs Y1 - 2005 ER - TY - JOUR A1 - Hoffmann, Petra T1 - Studienkollegs sind mehr als die Summe ihrer Schwerpunktkurse Y1 - 2005 ER - TY - JOUR A1 - Schroth, Giesela A1 - Hoffmann, Petra T1 - Bericht über die 30. Jahrestagung Deutsch als Fremdsprache an der Universität Essen vom 29. bis 31. Mai 2003 : Forum Deutsch als Fremdsprache Y1 - 2004 SN - 0724-9616 ER - TY - JOUR A1 - Hoffmann, Svenja A1 - Warschburger, Petra T1 - Weight, shape, and muscularity concerns in male and female adolescents BT - predictors of change and influences on eating concern JF - The international journal of eating disorders N2 - Objective: The purpose of this study was to examine the impact of age and weight status on adolescents' body dissatisfaction and its change over 20 months in a gender-comparing design. The influence of body image concern on eating concern was also investigated. Method: In a prospective study, 675 male and female adolescents aged 12–16 were assessed using self-report questionnaires on weight, shape, muscularity, and eating concerns. Height and weight measurements were taken by trained personnel. Data were analyzed using structural equation modeling. Results: Analyses of latent means revealed more pronounced weight/shape concern in females than males and more pronounced muscularity concern in males than females. Weight/shape concern increased in females over time, whereas muscularity concern remained stable in both genders. Baseline levels of weight/shape concern could be predicted by age and weight status in females and by weight status in males. The only predictor of change in weight/shape concern was weight status in males. Baseline levels of muscularity concern could be predicted by age in females and by weight status in males. Similar effects were found for changes in muscularity concern in both genders. Increases in weight/shape and muscularity concern were associated with more pronounced eating concern. Discussion: The results confirm gender differences in distinctive facets of body image concern and its prediction. The relevance of increase in body image concern in adolescents is underlined by its association with eating concern in both genders. Further explanatory variables for change in body dissatisfaction should be examined in future studies. KW - weight and shape concern KW - muscularity concern KW - eating concern KW - gender KW - adolescence KW - prospective Y1 - 2016 U6 - https://doi.org/10.1002/eat.22635 SN - 0276-3478 SN - 1098-108X VL - 50 IS - 2 SP - 139 EP - 147 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Hoffmann, Svenja A1 - Warschburger, Petra T1 - Prospective relations among internalization of beauty ideals, body image concerns, and body change behaviors BT - Considering thinness and muscularity JF - Body image : an international journal of research N2 - Common models propose that the internalization of societal beauty ideals influences disordered eating behaviors and muscularity-oriented behaviors via body image concerns. However, previous studies addressing these pathways have been mainly cross-sectional and primarily included female samples. We investigated these pathways prospectively in male and female adolescents and young adults, examining two pathways: a ‘weight/shape pathway,’ linking thin-ideal internalization, weight/shape concern, and restrained eating, and a ‘muscularity pathway,’ linking athletic-ideal internalization, muscularity concern, and muscularity-oriented behavior. Across three time points, 973 participants from the German general population were assessed. Although the hypothesized pathways could not be supported in their complete temporal sequence, several hypothesized pathways occurred across two time points. Among others, weight/shape concern predicted restrained eating and the athletic ideal played a prominent role in the prediction of muscularity-oriented behavior in both genders. KW - Weight/shape concern KW - Muscularity concern KW - Internalization KW - Restrained eating KW - Muscularity-oriented behavior KW - Prospective path analysis Y1 - 2019 U6 - https://doi.org/10.1016/j.bodyim.2019.01.011 SN - 1740-1445 SN - 1873-6807 VL - 28 SP - 159 EP - 167 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schründer-Lenzen, Agi A1 - Zimmermann, Matthias A1 - Görlich, Petra A1 - Horn-Conrad, Antje A1 - Geller, Katrin A1 - Eckardt, Barbara A1 - Hoffmann, Florian A1 - Pyanoe, Steffi A1 - Kampe, Heike A1 - Jäger, Sophie A1 - Reinhardt, Ragna T1 - Portal = Zwischen Freiheit und Verantwortung: Ethik in der Forschung BT - Das Potsdamer Universitätsmagazin N2 - Aus dem Inhalt: - Zwischen Freiheit und Verantwortung: Ethik in der Forschung - Die Grenzen der Grammatik - Ein Bild von einem Mann T3 - Portal: Das Potsdamer Universitätsmagazin - 02/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440475 SN - 1618-6893 IS - 02/2012 ER - TY - JOUR A1 - Günther, Oliver A1 - Görlich, Petra A1 - Hoffmann, Florian A1 - Zimmermann, Matthias A1 - Jäger, Sophie A1 - Weise, Aileen A1 - Wiehn, Tanja A1 - Eckardt, Barbara A1 - Rost, Sophia A1 - Klein, Armin A1 - Eulenfeld, Sophie T1 - Portal = Zwischen Hörsaal und Trainingsplatz: Studium und Leistungssport BT - Das Potsdamer Universitätsmagazin N2 - Aus dem Inhalt: - Zwischen Hörsaal und Trainingsplatz: Studium und Leistungssport - Studieren sans souci - Brisante Farbenlehre T3 - Portal: Das Potsdamer Universitätsmagazin - 03/2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440488 SN - 1618-6893 IS - 03/2012 ER - TY - JOUR A1 - Leitner, Ulrike A1 - Ette, Ottmar A1 - Kölbel, Bernd A1 - Sauerwein, Martin A1 - Sauerwein, Katrin A1 - Kölbel, Steffen A1 - Terken, Lucie A1 - Rupke, Nicolaas A. A1 - Weihrauch, Franz-J. A1 - Werner, Petra A1 - Hoffmann, Robert ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - HiN : Alexander von Humboldt im Netz N2 - - Ulrike Leitner: Aus dem Humboldt-Nachlaß: Juan José de Oteyzas Beschreibung der Pyramiden von Teotihuacán - Ottmar Ette: Alexander von Humboldt, die Humboldtsche Wissenschaft und ihre Relevanz im Netzzeitalter - Bernd Kölbel, Martin Sauerwein, Katrin Sauerwein, Steffen Kölbel und Lucie Terken: Alexander von Humboldt und seine geognostischen Studien in Göttingen - Nicolaas A. Rupke: A Metabiography of Alexander von Humboldt - Franz-J. Weihrauch: Nachrichten aus Amerika oder wie man in Koblenz von Humboldts Reise nach Amerika erfuhr - Petra Werner Himmelsblau. Bemerkungen zum Thema „Farben“ in Humboldts Alterswerk Kosmos. Entwurf einer physischen Weltbeschreibung - Robert Hoffmann: Die Entstehung einer Legende. Alexander von Humboldts angeblicher Ausspruch über Salzburg. T3 - HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies - VII.2006, 12 KW - Juan José de Oteyza KW - von Humboldts Hand KW - 1845-1862 KW - Kosmos KW - Netzwerke des Wissens KW - Netzzeitalter KW - Weltbegriff KW - Weltbewusstsein KW - Wissenschaftstheorie KW - „Mineralogische Beobachtungen über einige Basalte am Rhein“ KW - „Versuch über einige physikalische und chemische Grundsätze der Salzwerkskunde“ KW - 1790 KW - 1792 KW - Göttingen KW - neu gelesen KW - Steven Jan van Geuns KW - metabiography KW - „Bewohner des West Rheins“ KW - 1800 KW - A. F. de Fourcroy KW - Farbe KW - Himmelblau KW - 1870 KW - Salzburg Y1 - 2006 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-35481 SN - 1617-5239 SN - 2568-3543 N1 - Mit den Kategorien "von Humboldts Hand" und "neu gelesen" VL - VII IS - 12 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Hoffmann, Svenja A1 - Warschburger, Petra T1 - Body image in obese children and adolescents. Body dissatisfaction and body size perception in relation to quality of life and weight loss JF - Psychotherapeut N2 - Body dissatisfaction and an unrealistic perception of own body size are particularly common in obese children and adolescents; however, little is known about the association with weight-related quality of life and the impact on successful long-term weight loss. At the beginning of an inpatient child obesity rehabilitation program, 408 children and adolescents aged 9-12 years completed a questionnaire on body image (body silhouettes) and a body weight-specific questionnaire for overweight and obese children and adolescents (GW-LQ-KJ) on quality of life. Height and weight were measured by a physician at the beginning and 1 year after inpatient hospitalization. Of the participants 91.9 % reported body dissatisfaction and 75.7 % underestimated their own body size. There were no gender-specific differences in body dissatisfaction but boys perceived their body size more realistically than girls. Participants with body dissatisfaction and realistic body size perception showed a reduced weight-related quality of life. Those participants who realistically perceived their body size also lost less weight in the long term. The subjective underestimation of body size proved to be important for reduced weight-related quality of life and more pronounced long-term weight loss; therefore, body image should be taken into account in multimodal treatment programs. KW - Body size perception KW - Quality of life KW - Weight loss KW - Obesity KW - Questionnaire Y1 - 2015 U6 - https://doi.org/10.1007/s00278-015-0060-5 SN - 0935-6185 SN - 1432-2080 VL - 60 IS - 6 SP - 498 EP - 504 PB - Springer CY - New York ER - TY - JOUR A1 - Henkenborg-Schröder, Renate A1 - Hoffmann, Petra T1 - Kurzbericht zum Forum DaF : 29. Jahrestagung Deutsch als Fremdsprache an der Universität Kiel Y1 - 2001 ER - TY - JOUR A1 - Hoffmann, Petra A1 - Preuß, Siegbert T1 - Materialien zum Kooperationsprojekt VWL - DaF Y1 - 1999 ER - TY - JOUR A1 - Hoffmann, Petra T1 - DaF- und Fachunterricht : linguodidaktische Überlegungen zu einem Kooperationsprojekt VWL - DaF Y1 - 1999 SN - 1432-8208 ER - TY - JOUR A1 - Hoffmann, Petra T1 - Fachtagung "Deutsch als Fremdsprache an den Studienkollegs der Bundesrepublik Deutschland" vom 24. bis 26. September 1998 in Potsdam : Tagungsbericht Y1 - 1999 SN - 1432-8208 ER - TY - JOUR A1 - Landwehr-Kenzel, Sybille A1 - Zobel, Anne A1 - Hoffmann, Henrike A1 - Landwehr, Niels A1 - Schmueck-Henneresse, Michael A1 - Schachtner, Thomas A1 - Roemhild, Andy A1 - Reinke, Petra T1 - Ex vivo expanded natural regulatory T cells from patients with end-stage renal disease or kidney transplantation are useful for autologous cell therapy JF - Kidney international : official journal of the International Society of Nephrology N2 - Novel concepts employing autologous, ex vivo expanded natural regulatory T cells (nTreg) for adoptive transfer has potential to prevent organ rejection after kidney transplantation. However, the impact of dialysis and maintenance immunosuppression on the nTreg phenotype and peripheral survival is not well understood, but essential when assessing patient eligibility. The current study investigates regulatory T-cells in dialysis and kidney transplanted patients and the feasibility of generating a clinically useful nTreg product from these patients. Heparinized blood from 200 individuals including healthy controls, dialysis patients with end stage renal disease and patients 1, 5, 10, 15, 20 years after kidney transplantation were analyzed. Differentiation and maturation of nTregs were studied by flow cytometry in order to compare dialysis patients and kidney transplanted patients under maintenance immunosuppression to healthy controls. CD127 expressing CD4(+)CD25(high)FoxP3(+) nTregs were detectable at increased frequencies in dialysis patients with no negative impact on the nTreg end product quality and therapeutic usefulness of the ex vivo expanded nTregs. Further, despite that immunosuppression mildly altered nTreg maturation, neither dialysis nor pharmacological immunosuppression or previous acute rejection episodes impeded nTreg survival in vivo. Accordingly, the generation of autologous, highly pure nTreg products is feasible and qualifies patients awaiting or having received allogenic kidney transplantation for adoptive nTreg therapy. Thus, our novel treatment approach may enable us to reduce the incidence of organ rejection and reduce the need of long-term immunosuppression. KW - adoptive T-cell transfer KW - autologous cell therapy KW - end-stage renal disease KW - kidney transplantation KW - regulatory T cells Y1 - 2018 U6 - https://doi.org/10.1016/j.kint.2018.01.021 SN - 0085-2538 SN - 1523-1755 VL - 93 IS - 6 SP - 1452 EP - 1464 PB - Elsevier CY - New York ER - TY - BOOK A1 - Siehr, Karl-Heinz A1 - Kern, Friederike A1 - Hoffmann, Michael A1 - Großbröhmer, Christoph A1 - Mühlbauer, Evelyn A1 - Berner, Elisabeth A1 - Leubner, Martin A1 - Friese, Antonia A1 - Preis, Matthias A1 - Josting, Petra A1 - Höfner, Marion A1 - Schepe, Kerstin ED - Kern, Friederike ED - Siehr, Karl-Heinz T1 - Sport als Thema im Deutschunterricht BT - Fachliche Grundlagen – Unterrichtsanregungen – Unterrichtsmaterialien N2 - Ein Deutschunterricht, der die Alltags- und Medienkultur der Schüler und Schülerinnen ernst nimmt, darf Sporttexte nicht unberücksichtigt lassen. Zu sehr ist der Sport in all seinen Facetten Teil der Lebenswelt vieler Schülerinnen und Schüler geworden. Die Frage ist nicht mehr, ob der Deutschunterricht darauf zu reagieren hat, die Frage ist vielmehr, wie er dies tun und welche Sporttexte er dabei nutzen kann. Auch wenn die Suche nach sinnvollen Bezügen zwischen Sport und Deutschunterricht schon seit längerem intensiv betrieben wird, offenbart das vielschichtige Kulturphänomen „Sport“ immer wieder neue interessante Seiten, die es lohnen, fachdidaktisch behandelt zu werden. Die zehn Beiträge in diesem Band verstehen sich als Unterrichtsanregungen für den kompetenzorientierten Deutschunterricht. Sie bedienen Betrachtungen zum Sport aus literarischer, sprachlicher und medialer Perspektive. Die theoretisch-begrifflichen Aspekte der jeweiligen Themen werden soweit behandelt, wie sie für das Verständnis erforderlich sind. Im Zentrum vieler Beiträge stehen Unterrichtsszenarien mit kommentierten Texten und Aufgaben, die für die Unterrichtsvorbereitung oder für den Unterricht selbst genutzt werden können. KW - Deutschunterricht KW - Sportsprache KW - Varietäten KW - Sportberichterstattung KW - Medienanalyse KW - Deutschdidaktik Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-95307 SN - 978-3-86956-381-7 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Peter, Lena A1 - Wendering, Désirée Jacqueline A1 - Schlickeiser, Stephan A1 - Hoffmann, Henrike A1 - Noster, Rebecca A1 - Wagner, Dimitrios Laurin A1 - Zarrinrad, Ghazaleh A1 - Münch, Sandra A1 - Picht, Samira A1 - Schulenberg, Sarah A1 - Moradian, Hanieh A1 - Mashreghi, Mir-Farzin A1 - Klein, Oliver A1 - Gossen, Manfred A1 - Roch, Toralf A1 - Babel, Nina A1 - Reinke, Petra A1 - Volk, Hans-Dieter A1 - Amini, Leila A1 - Schmueck-Henneresse, Michael T1 - Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients JF - Molecular therapy methods and clinical development N2 - Solid organ transplant (SOT) recipients receive therapeutic immunosuppression that compromises their immune response to infections and vaccines. For this reason, SOT patients have a high risk of developing severe coronavirus disease 2019 (COVID-19) and an increased risk of death from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Moreover, the efficiency of immunotherapies and vaccines is reduced due to the constant immunosuppression in this patient group. Here, we propose adoptive transfer of SARS-CoV-2-specific T cells made resistant to a common immunosuppressant, tacrolimus, for optimized performance in the immunosuppressed patient. Using a ribonucleoprotein approach of CRISPR-Cas9 technology, we have generated tacrolimus-resistant SARS-CoV-2-specific T cell products from convalescent donors and demonstrate their specificity and function through characterizations at the single-cell level, including flow cytometry, single-cell RNA (scRNA) Cellular Indexing of Transcriptomes and Epitopes (CITE), and T cell receptor (TCR) sequencing analyses. Based on the promising results, we aim for clinical validation of this approach in transplant recipients. Additionally, we propose a combinatory approach with tacrolimus, to prevent an overshooting immune response manifested as bystander T cell activation in the setting of severe COVID-19 immunopathology, and tacrolimus-resistant SARS-CoV-2-specific T cell products, allowing for efficient clearance of viral infection. Our strategy has the potential to prevent severe COVID-19 courses in SOT or autoimmunity settings and to prevent immunopathology while providing viral clearance in severe non-transplant COVID-19 cases. Y1 - 2022 U6 - https://doi.org/10.1016/j.omtm.2022.02.012 SN - 2329-0501 VL - 25 SP - 52 EP - 73 PB - Cell Press CY - Cambridge ER -