TY - JOUR A1 - VanDerLoop, Frank T. L. A1 - VanDerVen, Peter F. M A1 - Fürst, Dieter Oswald A1 - Gautel, Mathias A1 - VanEys, Guillaume A1 - Ramaekers, Frans C. S. T1 - Integration of titin into the sarcomeres of cultured differentiating human skeletal muscle cells Y1 - 1996 ER - TY - JOUR A1 - Speel, Ernst J. M. A1 - VanDerVen, Peter F. M. A1 - Albrechts, Jozefa C. M. A1 - Hopman, Anton H. N. A1 - Fürst, Dieter Oswald T1 - Chromosomal assignment of the human myomesin gene Y1 - 1998 ER - TY - JOUR A1 - Speel, Ernst J. M. A1 - VanDerVen, Peter F. M. A1 - Albrechts, Jozefa C. M. A1 - Ramaekers, Frans C. S. A1 - Fürst, Dieter Oswald A1 - Hopman, Anton H. N. T1 - Assignment of the human gene for the sarcomeric M-band protein myomesin (MYOM1) to 18p11.31-p11.32 Y1 - 1998 ER - TY - JOUR A1 - VanDerVen, Peter F. M. A1 - Speel, Ernst J. M. A1 - Albrechts, Jozefa C. M. A1 - Ramaekers, Frans C. S. A1 - Hopman, Anton H. N. A1 - Fürst, Dieter Oswald T1 - Chromosomal assignment of the human gene for endosarcomeric cytoskeletal M-protein (MYOM2) to 8p23.3 Y1 - 1999 ER - TY - JOUR A1 - VanDerVen, Peter F. M. A1 - Speel, Ernst J. M. A1 - Albrechts, Jozefa C. M. A1 - Ramaekers, Frans C. S. A1 - Hopman, Anton H. N. A1 - Fürst, Dieter Oswald T1 - Assignment of the human gene for endosarcomeric cytoskeletal M-protein (MYOM2) to 8p23.3 Y1 - 1999 ER - TY - JOUR A1 - Obermann, Wolfgang A1 - Gautel, Mathias A1 - Steiner, F. A1 - VanDerVen, Peter F. M. A1 - Weber, Klaus A1 - Fürst, Dieter Oswald T1 - The structure of the sarcomeric M band : localization of defined domains of myomesin, M-protein, and the 250-kD carboxy-terminal region of titin by immunoelectron microscopy Y1 - 1996 ER - TY - JOUR A1 - Schröder, Rolf A1 - VanDerVen, Peter F. M. A1 - Warlo, Irene A1 - Schumann, H. A1 - Fürst, Dieter Oswald A1 - Blümke, Ingmar A1 - Goebel, Hans H. A1 - Schmidt, M. C. A1 - Hatzfeld, Mechthild T1 - A member of the armadillo multigene family, is a constituent of sarcomeric I-bands in human skeletal muscle Y1 - 2000 ER - TY - JOUR A1 - Obermann, Wolfgang A1 - VanDerVen, Peter F. M A1 - Steiner, F. A1 - Weber, Klaus A1 - Fürst, Dieter Oswald T1 - Mapping of a myosin binding domain and a regulatory phosphorylation site in M-protein, a structural protein of the sarcomeric M-band Y1 - 1998 ER - TY - JOUR A1 - Gehmlich, Katja A1 - Hayess, Katrin A1 - Legler, Christof A1 - Haebel, Sophie A1 - van der Ven, Peter F. M. A1 - Ehler, Elisabeth A1 - Fuerst, Dieter O. T1 - Ponsin interacts with Nck adapter proteins : implications for a role in cytoskeletal remodelling during differentiation of skeletal muscle cells N2 - Skeletal muscle differentiation is a complex process: It is characterised by changes in gene expression and protein composition. Simultaneously, a dramatic remodelling of the cytoskeleton and associated cell-matrix contacts, the costameres, occurs. The expression and localisation of the protein ponsin at cell-matrix contacts marks the establishment of costameres. In this report we show that skeletal muscle cells are characterised by a novel ponsin isoform, which contains a large insertion in its carboxy-terminus. This skeletal muscle-specific module binds the adapter proteins Nck1 and Nck2, and increased co-localisation of ponsin with Nck2 is observed at remodelling cell-matrix contacts of differentiating skeletal muscle cells. Since this ponsin insertion can be phosphorylated, it may adjust the interaction affinity with Nck adapter proteins. The novel ponsin isoform and its interaction with Nck1/2 provide exciting insight into the convergence of signalling pathways at the costameres, and its crucial role for skeletal muscle differentiation and re-generation. Y1 - 2010 UR - http://www.sciencedirect.com/science/journal/01719335 U6 - https://doi.org/10.1016/j.ejcb.2009.10.019 SN - 0171-9335 ER - TY - JOUR A1 - Schröder, Rolf A1 - Fürst, Dieter Oswald A1 - Klasen, Christian A1 - Reiman, Jens A1 - Herrmann, Harald A1 - VanDerVen, Peter F. M. T1 - The association of plectin with Z-discs is a prerequisite for the formation of the intermyofibrillar desmin cytoskeleton Y1 - 2000 ER - TY - JOUR A1 - VanDerVen, Peter F. M. A1 - Bartsch, Jörg A1 - Gautel, Mathias A1 - Jokusch, Harald A1 - Fürst, Dieter Oswald T1 - A functional knock-out of titin results in defective myofibril assembly Y1 - 2000 ER - TY - JOUR A1 - VanDerVen, Peter F. M A1 - Obermann, Wolfgang A1 - Weber, Klaus A1 - Fürst, Dieter Oswald T1 - Myomesin, M-protein and the structure of the sarcomeric M-band Y1 - 1996 ER - TY - JOUR A1 - Mayans, Olga A1 - VanDerVen, Peter F. M A1 - Wilmanns, Matthias A1 - Mues, Alexander A1 - Young, Paul A1 - Fürst, Dieter Oswald A1 - Wilmanns, Matthias A1 - Gautel, Mathias T1 - The structural basis of the activation of the serine kinase domain of the giant muscle protein titin during myofibrillogenesis Y1 - 1998 ER - TY - JOUR A1 - VanDerVen, Peter F. M A1 - Fürst, Dieter Oswald T1 - Expression of sarcomeric proteins and assembly of myofibrils in the putative myofibroblast cell line BHK-21/C13 Y1 - 1998 ER - TY - JOUR A1 - VanDerVen, Peter F. M A1 - Fürst, Dieter Oswald T1 - Assembly of titin, myomesin and M-protein into the sarcomeric M-band in differentiating human skeletal muscle cells in vitro Y1 - 1997 ER - TY - JOUR A1 - Mues, Alexander A1 - VanDerVen, Peter F. M A1 - Young, Paul A1 - Fürst, Dieter Oswald A1 - Gautel, Mathias T1 - Two immunoglobulin-like domains of the Z-disk portion of titin interact in a conformation-dependent way with telethonin Y1 - 1998 ER - TY - JOUR A1 - VanDerVen, Peter F. M A1 - Obermann, Wolfgang A1 - Lemke, Britt A1 - Gautel, Mathias A1 - Weber, Klaus A1 - Fürst, Dieter Oswald T1 - The characterization of muscle filamin isoforms suggests a possible role of ABP-L/gamma-filamin in sarcomeric Z- disc formation Y1 - 2000 ER - TY - JOUR A1 - Fürst, Dieter Oswald A1 - Obermann, Wolfgang A1 - VanDerVen, Peter F. M T1 - Structure and assembly of the sarcomeric M-band Y1 - 1999 ER - TY - JOUR A1 - Schröder, Rolf A1 - Warlo, Irene A1 - Herrmann, Harald A1 - VanDerVen, Peter F. M A1 - Klasen, Christian A1 - Blümke, Ingmar A1 - Mundegar, Rustam R. A1 - Fürst, Dieter Oswald A1 - Göbel, Hans H. A1 - Magin, Thomas T1 - Immunogold EM reveals a close association of plectin and the desmin cytoskeleton in human skeletal muscle Y1 - 1999 ER -