TY - JOUR A1 - Pietra, Stefano A1 - Lang, Patricia A1 - Grebe, Markus T1 - SABRE is required for stabilization of root hair patterning in Arabidopsis thaliana JF - Physiologia Plantarum N2 - Patterned differentiation of distinct cell types is essential for the development of multicellular organisms. The root epidermis of Arabidopsis thaliana is composed of alternating files of root hair and non-hair cells and represents a model system for studying the control of cell-fate acquisition. Epidermal cell fate is regulated by a network of genes that translate positional information from the underlying cortical cell layer into a specific pattern of differentiated cells. While much is known about the genes of this network, new players continue to be discovered. Here we show that the SABRE (SAB) gene, known to mediate microtubule organization, anisotropic cell growth and planar polarity, has an effect on root epidermal hair cell patterning. Loss of SAB function results in ectopic root hair formation and destabilizes the expression of cell fate and differentiation markers in the root epidermis, including expression of the WEREWOLF (WER) and GLABRA2 (GL2) genes. Double mutant analysis reveal that wer and caprice (cpc) mutants, defective in core components of the epidermal patterning pathway, genetically interact with sab. This suggests that SAB may act on epidermal patterning upstream of WER and CPC. Hence, we provide evidence for a role of SAB in root epidermal patterning by affecting cell-fate stabilization. Our work opens the door for future studies addressing SAB-dependent functions of the cytoskeleton during root epidermal patterning. Y1 - 2015 UR - http://onlinelibrary.wiley.com/doi/10.1111/ppl.12257/epdf U6 - https://doi.org/DOI: 10.1111/ppl.12257 VL - 153 IS - 3 SP - 440 EP - 453 ER - TY - JOUR A1 - Clahsen, Harald A1 - Siegmüller, Julia A1 - Penke, Martina A1 - Schröder, Astrid A1 - Hofmann, Janine A1 - Holzgrefe-Lang, Julia A1 - Skerra, Antje A1 - Adani, Flavia A1 - Gagarina, Natalʹja Vladimirovna A1 - Schröter, Carolin A1 - Frieg, Hendrike A1 - Belke, Eva A1 - Schwab, Susanne A1 - Seifert, Susanne A1 - Watko, Petra A1 - Obendrauf, Tanja A1 - Trauntschnig, Mike A1 - Gasteiger-Klicpera, Barbara A1 - Adelt, Anne A1 - Hanne, Sandra A1 - Burchert, Frank A1 - Swietza, Romy A1 - Doppelbauer, Lea A1 - Dralle, Jenny A1 - Purat, Patricia A1 - Webersinke, Dorothea A1 - Schwytay, Jeannine A1 - Stadie, Nicole A1 - Hoppe, Carina A1 - Heide, Judith A1 - Marusch, Tina A1 - von der Malsburg, Titus Raban A1 - Bastiaanse, Roelien A1 - Schultheiss, Corinna A1 - Nahrstaedt, Holger A1 - Schauer, Thomas A1 - Seidl, Rainer Ottis A1 - Rath, Elisa ED - Fritzsche, Tom ED - Meyer, Corinna B. ED - Adelt, Anne ED - Roß, Jennifer T1 - Spektrum Patholinguistik = Schwerpunktthema: Labyrinth Grammatik: Therapie von syntaktischen Störungen bei Kindern und Erwachsenen N2 - Das Herbsttreffen Patholinguistik wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Das 6. Herbsttreffen mit dem Schwerpunktthema "Labyrinth Grammatik: Therapie von syntaktischen Störungen bei Kindern und Erwachsenen" fand am 17.11.2012 in Potsdam statt. Im vorliegenden Tagungsband finden sich alle Beiträge der Veranstaltung: die vier Hauptvorträge zum Schwerpunkthema, die Vorträge aus Praxis und Forschung von vier Patholinguistinnen in der Reihe Spektrum Patholinguistik sowie die Abstracts der Posterpräsentation. N2 - The 'Herbsttreffen Patholinguistik' is an annual conference organized by the Association for Patholinguistics (Verband für Patholinguistik e.V./vpl) since 2007. The 6th Herbsttreffen with its theme "Labyrinth Grammar: Therapy of Syntactic Disorders in Children and Adults" took place on November 17th, 2012 in Potsdam. These proceedings contain all contributions of the meeting: the four keynote talks, the talks on speech/language therapy and research in the section "Spektrum Patholinguistik" by four patholinguists as well as the abstracts of the poster session. T3 - Spektrum Patholinguistik - 6 KW - Patholinguistik KW - syntaktische Störungen KW - Aphasie KW - Agrammatismus KW - Dysgrammatismus KW - patholinguistics KW - speech/language therapy KW - syntactic disorders KW - aphasia KW - agrammatism Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-67659 SN - 978-3-86956-270-4 SN - 1869-3822 SN - 1866-9433 IS - 6 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Pietra, Stefano A1 - Lang, Patricia A1 - Grebe, Markus T1 - SABRE is required for stabilization of root hair patterning in Arabidopsis thaliana JF - Physiologia plantarum N2 - Patterned differentiation of distinct cell types is essential for the development of multicellular organisms. The root epidermis of Arabidopsis thaliana is composed of alternating files of root hair and non-hair cells and represents a model system for studying the control of cell-fate acquisition. Epidermal cell fate is regulated by a network of genes that translate positional information from the underlying cortical cell layer into a specific pattern of differentiated cells. While much is known about the genes of this network, new players continue to be discovered. Here we show that the SABRE (SAB) gene, known to mediate microtubule organization, anisotropic cell growth and planar polarity, has an effect on root epidermal hair cell patterning. Loss of SAB function results in ectopic root hair formation and destabilizes the expression of cell fate and differentiation markers in the root epidermis, including expression of the WEREWOLF (WER) and GLABRA2 (GL2) genes. Double mutant analysis reveal that wer and caprice (cpc) mutants, defective in core components of the epidermal patterning pathway, genetically interact with sab. This suggests that SAB may act on epidermal patterning upstream of WER and CPC. Hence, we provide evidence for a role of SAB in root epidermal patterning by affecting cell-fate stabilization. Our work opens the door for future studies addressing SAB-dependent functions of the cytoskeleton during root epidermal patterning. Y1 - 2015 U6 - https://doi.org/10.1111/ppl.12257 SN - 0031-9317 SN - 1399-3054 VL - 153 IS - 3 SP - 440 EP - 453 PB - Wiley-Blackwell CY - Hoboken ER -