TY  - JOUR
A1  - Sarrar, Lea
A1  - Holzhausen, Martin
A1  - Warschburger, Petra
A1  - Pfeiffer, Ernst
A1  - Lehmkuhl, Ulrike
A1  - Schneider, Nora
T1  - Cognitive Function in Adolescent Patients with Anorexia Nervosa and Unipolar Affective Disorders
JF  - European eating disorders review : the professional journal of the Eating Disorders Associatio
N2  - Studies have shown impairments in cognitive function among adult patients with anorexia nervosa (AN) and affective disorders (AD). The association between cognitive dysfunctions, AN and AD as well as the specificity for these psychiatric diagnoses remains unclear. Therefore, we examined cognitive flexibility and processing speed in 47 female adolescent patients with AN, 21 female adolescent patients with unipolar affective disorders and 48 female healthy adolescents. All participants completed a neuropsychological test battery. There were no significant group differences regarding cognitive function, except for psychomotor processing speed with poorer performance in patients with AN. A further analysis revealed that all groups performed with the normal range, although patients with AN were over represented in the poorest performing quartile. We found no severe cognitive impairments in either patient group. Nevertheless, belonging to the AN group contributed significantly to poor performances in neuropsychological tasks. Therefore, we conclude that the risk for cognitive impairments is slightly higher for patients with AN. Copyright (c) 2015 John Wiley & Sons, Ltd and Eating Disorders Association.
KW  - cognitive function
KW  - anorexia nervosa
KW  - unipolar affective disorders
KW  - adolescents
Y1  - 2016
U6  - https://doi.org/10.1002/erv.2425
SN  - 1072-4133
SN  - 1099-0968
VL  - 24
SP  - 232
EP  - 240
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Walter, Tim
A1  - Collenburg, Lena
A1  - Japtok, Lukasz
A1  - Kleuser, Burkhard
A1  - Schneider-Schaulies, Sibylle
A1  - Müller, Nora
A1  - Becam, Jerome
A1  - Schubert-Unkmeir, Alexandra
A1  - Kong, Ji Na
A1  - Bieberich, Erhard
A1  - Seibel, Jürgen
T1  - Incorporation and visualization of azido-functionalized N-oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells
N2  - The synthesis and biological evaluation of azido-N-oleoyl serinol is reported. It mimicks biofunctional lipid ceramides and has shown to be capable of click reactions for cell membrane imaging in Jurkat and human brain microvascular endothelial cells.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 324 
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-394960
ER  - 
TY  - JOUR
A1  - Collenburg, Lena
A1  - Walter, Tim
A1  - Burgert, Anne
A1  - Mueller, Nora
A1  - Seibel, Juergen
A1  - Japtok, Lukasz
A1  - Kleuser, Burkhard
A1  - Sauer, Markus
A1  - Schneider-Schaulies, Sibylle
T1  - A Functionalized Sphingolipid Analogue for Studying Redistribution during Activation in Living T Cells
JF  - The journal of immunology
N2  - Sphingolipids are major components of the plasma membrane. In particular, ceramide serves as an essential building hub for complex sphingolipids, but also as an organizer of membrane domains segregating receptors and signalosomes. Sphingomyelin breakdown as a result of sphingomyelinase activation after ligation of a variety of receptors is the predominant source of ceramides released at the plasma membrane. This especially applies to T lymphocytes where formation of ceramide-enriched membrane microdomains modulates TCR signaling. Because ceramide release and redistribution occur very rapidly in response to receptor ligation, novel tools to further study these processes in living T cells are urgently needed. To meet this demand, we synthesized nontoxic, azido-functionalized ceramides allowing for bio-orthogonal click-reactions to fluorescently label incorporated ceramides, and thus investigate formation of ceramide-enriched domains. Azido-functionalized C-6-ceramides were incorporated into and localized within plasma membrane microdomains and proximal vesicles in T cells. They segregated into clusters after TCR, and especially CD28 ligation, indicating efficient sorting into plasma membrane domains associated with T cell activation; this was abolished upon sphingomyelinase inhibition. Importantly, T cell activation was not abrogated upon incorporation of the compound, which was efficiently excluded from the immune synapse center as has previously been seen in Ab-based studies using fixed cells. Therefore, the functionalized ceramides are novel, highly potent tools to study the subcellular redistribution of ceramides in the course of T cell activation. Moreover, they will certainly also be generally applicable to studies addressing rapid stimulation-mediated ceramide release in living cells.
Y1  - 2016
U6  - https://doi.org/10.4049/jimmunol.1502447
SN  - 0022-1767
SN  - 1550-6606
VL  - 196
SP  - 3951
EP  - 3962
PB  - American Assoc. of Immunologists
CY  - Bethesda
ER  - 
TY  - JOUR
A1  - Iven, Claudia
A1  - Hansen, Bernd
A1  - Anders, Kristina
A1  - Starke, Andreas
A1  - Richardt, Kirsten
A1  - Prüß, Holger
A1  - El Meskioui, Martina
A1  - Haase, Tobias
A1  - Mahlberg, Lea
A1  - Wiehe, Lea
A1  - de Beer, Carola
A1  - Niepelt Karampamapa, Rebekka
A1  - Hofmann, Andrea
A1  - Stadie, Nicole
A1  - Hanne, Sandra
A1  - Thomson, Jenny
A1  - Schäfer, Blanca
A1  - Huttenlauch, Clara
A1  - Wartenburger, Isabell
A1  - Weiland, Katharina
A1  - Wirsam, Anke
A1  - Hartung, Julia
A1  - Wahl, Michael
A1  - Unger, Julia
A1  - Buschmann, Anke
A1  - Seefeld, Martin
A1  - Bethge, Anita
A1  - Fieder, Nora
A1  - Rahman, Rasha Abdel
A1  - Nousair, Iman
A1  - Klassert, Annegret
A1  - Wellmann, Caroline
A1  - Verbree, Rahel
A1  - van Rij, Jacolien
A1  - Sprenger, Simone
A1  - Mähl, Anna Luisa
A1  - Schneider, Kathleen
A1  - Kutz, Anne
A1  - Kaps, Hella
A1  - Frank, Ulrike
A1  - Brekeller, Sophie
A1  - Ryll, Katja
ED  - Breitenstein, Sarah
ED  - Burmester, Juliane
ED  - Yetim, Özlem
ED  - Fritzsche, Tom
T1  - Spektrum Patholinguistik Band 12. Schwerpunktthema: Weg(e) mit dem Stottern: Therapie und Selbsthilfe für Kinder und Erwachsene
T2  - Spektrum Patholinguistik
N2  - Das 12. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Weg(e) mit dem Stottern: Therapie und Selbsthilfe für Kinder und Erwachsene« fand am 24.11.2018 in Potsdam statt. Das Herbsttreffen wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Der vorliegende Tagungsband beinhaltet die Vorträge zum Schwerpunktthema sowie Beiträge der Posterpräsentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis.
N2  - The Twelfth Autumn Meeting Patholinguistics (Herbsttreffen Patholinguistik) with its main topic »Away/A way with stuttering: Therapy and self-help for children and adults« took place in Potsdam on November 24 2018. This annual meeting has been organised since 2007 by the Association for Patholinguistics (Verband für Patholinguistik e.V./vpl). The present proceedings contain all talks on the main topic as well as contributions from the poster session covering a broad range of areas in speech/language therapy research and practice.
T3  - Spektrum Patholinguistik - 12 
KW  - Patholinguistik
KW  - Sprachtherapie
KW  - Stottern
KW  - Redeflussstörungen
KW  - Selbsthilfe
KW  - patholinguistics
KW  - speech/language therapy
KW  - stuttering
KW  - fluency disorder
KW  - self-help
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-437002
SN  - 978-3-86956-479-1
SN  - 1866-9085
SN  - 1866-9433
IS  - 12
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Schneider, Matthias
A1  - Fritzsche, Nora
A1  - Puciul-Malinowska, Agnieszka
A1  - Baliś, Andrzej
A1  - Mostafa, Amr
A1  - Bald, Ilko
A1  - Zapotoczny, Szczepan
A1  - Taubert, Andreas
T1  - Surface etching of 3D printed poly(lactic acid) with NaOH
BT  - a systematic approach
JF  - Polymers
N2  - The article describes a systematic investigation of the effects of an aqueous NaOH treatment of 3D printed poly(lactic acid) (PLA) scaffolds for surface activation. The PLA surface undergoes several morphology changes and after an initial surface roughening, the surface becomes smoother again before the material dissolves. Erosion rates and surface morphologies can be controlled by the treatment. At the same time, the bulk mechanical properties of the treated materials remain unaltered. This indicates that NaOH treatment of 3D printed PLA scaffolds is a simple, yet viable strategy for surface activation without compromising the mechanical stability of PLA scaffolds.
KW  - surface modification
KW  - sodium hydroxide etching
KW  - poly(lactic acid)
KW  - 3D
KW  - printing
KW  - roughness
KW  - wettability
KW  - erosion
Y1  - 2020
U6  - https://doi.org/10.3390/polym12081711
SN  - 2073-4360
VL  - 12
IS  - 8
PB  - MDPI
CY  - Basel
ER  - 
TY  - GEN
A1  - Schneider, Matthias
A1  - Fritzsche, Nora
A1  - Puciul-Malinowska, Agnieszka
A1  - Balis, Andrzej
A1  - Mostafa, Amr
A1  - Bald, Ilko
A1  - Zapotoczny, Szczepan
A1  - Taubert, Andreas
T1  - Surface etching of 3D printed poly(lactic acid) with NaOH: a systematic approach
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - The article describes a systematic investigation of the effects of an aqueous NaOH treatment of 3D printed poly(lactic acid) (PLA) scaffolds for surface activation. The PLA surface undergoes several morphology changes and after an initial surface roughening, the surface becomes smoother again before the material dissolves. Erosion rates and surface morphologies can be controlled by the treatment. At the same time, the bulk mechanical properties of the treated materials remain unaltered. This indicates that NaOH treatment of 3D printed PLA scaffolds is a simple, yet viable strategy for surface activation without compromising the mechanical stability of PLA scaffolds.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1212 
KW  - surface modification
KW  - sodium hydroxide etching
KW  - poly(lactic acid)
KW  - 3D printing
KW  - roughness
KW  - wettability
KW  - erosion
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-525088
SN  - 1866-8372
IS  - 8
ER  - 
TY  - JOUR
A1  - Schneider, Matthias
A1  - Fritzsche, Nora
A1  - Puciul-Malinowska, Agnieszka
A1  - Balis, Andrzej
A1  - Mostafa, Amr
A1  - Bald, Ilko
A1  - Zapotoczny, Szczepan
A1  - Taubert, Andreas
T1  - Surface etching of 3D printed poly(lactic acid) with NaOH: a systematic approach
JF  - Polymers
N2  - The article describes a systematic investigation of the effects of an aqueous NaOH treatment of 3D printed poly(lactic acid) (PLA) scaffolds for surface activation. The PLA surface undergoes several morphology changes and after an initial surface roughening, the surface becomes smoother again before the material dissolves. Erosion rates and surface morphologies can be controlled by the treatment. At the same time, the bulk mechanical properties of the treated materials remain unaltered. This indicates that NaOH treatment of 3D printed PLA scaffolds is a simple, yet viable strategy for surface activation without compromising the mechanical stability of PLA scaffolds.
KW  - surface modification
KW  - sodium hydroxide etching
KW  - poly(lactic acid)
KW  - 3D printing
KW  - roughness
KW  - wettability
KW  - erosion
Y1  - 2020
VL  - 12
IS  - 8
PB  - MDPI
CY  - Basel
ER  -