TY  - JOUR
A1  - Koehler, Friedrich
A1  - Koehler, Kerstin
A1  - Deckwart, Oliver
A1  - Prescher, Sandra
A1  - Wegscheider, Karl
A1  - Winkler, Sebastian
A1  - Vettorazzi, Eik
A1  - Polze, Andreas
A1  - Stangl, Karl
A1  - Hartmann, Oliver
A1  - Marx, Almuth
A1  - Neuhaus, Petra
A1  - Scherf, Michael
A1  - Kirwan, Bridget-Anne
A1  - Anker, Stefan D.
T1  - Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients
BT  - study design and description of the intervention
JF  - European Journal of Heart Failure
N2  - Background Heart failure (HF) is a complex, chronic condition that is associated with debilitating symptoms, all of which necessitate close follow-up by health care providers. Lack of disease monitoring may result in increased mortality and more frequent hospital readmissions for decompensated HF. Remote patient management (RPM) in this patient population may help to detect early signs and symptoms of cardiac decompensation, thus enabling a prompt initiation of the appropriate treatment and care before a manifestation of HF decompensation. Objective The objective of the present article is to describe the design of a new trial investigating the impact of RPM on unplanned cardiovascular hospitalisations and mortality in HF patients. Methods The TIM-HF2 trial is designed as a prospective, randomised, controlled, parallel group, open (with randomisation concealment), multicentre trial with pragmatic elements introduced for data collection. Eligible patients with HF are randomised (1:1) to either RPM + usual care or to usual care only and are followed for 12 months. The primary outcome is the percentage of days lost due to unplanned cardiovascular hospitalisations or all-cause death. The main secondary outcomes are all-cause and cardiovascular mortality. Conclusion The TIM-HF2 trial will provide important prospective data on the potential beneficial effect of telemedical monitoring and RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.
KW  - Chronic heart failure
KW  - Telemonitoring
KW  - Remote patient management
KW  - Hospitalisation
Y1  - 2018
U6  - https://doi.org/10.1002/ejhf.1300
SN  - 1388-9842
SN  - 1879-0844
VL  - 20
IS  - 10
SP  - 1485
EP  - 1493
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - THES
A1  - Marx, Sebastian
T1  - Europäische Sicherheitspolitik am Bosporus : Perspektiven europäischer Sicherheit bei einem EU-Beitritt oder bei einer privilegierten Partnerschaft der Türkei
T1  - European security politics at the Bosporus : perspectives of european security with an EU-membership or a privileged partnership of Turkey
N2  - Diese Arbeit behandelt die Frage, welche Auswirkungen eine EU-Mitgliedschaft der Türkei auf die europäischen Sicherheitsbeziehungen haben würde. Es wird die sicherheitspolitische Situation in- und außerhalb der türkischen Staatsgrenzen analysiert. Auf Basis der Rational Choice Theorie vom Akteurzentrierten Institutionalismus wird gezeigt mit welchen Herausforderungen die Europäische Union konfrontiert wäre und die Frage behandelt, ob eine so genannte Privilegierte Partnerschaft eine mögliche Alternative zu einer Vollmitgliedschaft sein kann.
N2  - This work deals with the question which impact an EU-membership of Turkey would have on European security relations. It analyzes the security situation in- and outside Turkeys frontiers. Based on the rational choice theory of Akteurzentrierter Institutionalismus it tries to give a prospect of possible challenges for the European Union and brings up the question whether a so called privileged partnership is a possible altnernative to a full membership.
KW  - Europäische Union / Erweiterung
KW  - Europa / Sicherheitspolitik
KW  - Gemeinsame Außen- und Sicherheitspolitik
KW  - Europäische Integration
KW  - Privilegierte Partnerschaft
KW  - EU-Vollmitgliedschaft
KW  - Türkei
KW  - Privileged Partnership
KW  - EU-Membership
KW  - Turkey
Y1  - 2005
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-5776
ER  - 
TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Aharonian, Felix A.
A1  - Ait Benkhali, Faical
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Arrieta, M.
A1  - Backes, Michael
A1  - Barnard, M.
A1  - Becherini, Yvonne
A1  - Tjus, J. Becker
A1  - Berge, D.
A1  - Bernhard, S.
A1  - Bernlöhr, Konrad
A1  - Blackwell, R.
A1  - Böttcher, Markus
A1  - Boisson, C.
A1  - Bolmont, Julien
A1  - Bonnefoy, S.
A1  - Bordas, Pol
A1  - Bregeon, J.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Büchele, M.
A1  - Bulik, Tomasz
A1  - Bylund, Tomas
A1  - Capasso, Massimo
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, Matteo
A1  - Chakraborty, Nachiketa
A1  - Chandra, S.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Colafrancesco, Sergio
A1  - Condon, B.
A1  - Davids, Isak
A1  - Deil, Christoph
A1  - Devin, J.
A1  - deWilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Dmytriiev, A.
A1  - Donath, Axel
A1  - Doroshenko, Victor
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J. -P.
A1  - Eschbach, Stefan
A1  - Fegan, S.
A1  - Fiasson, Armand
A1  - Fontaine, G.
A1  - Funk, Sebastian
A1  - Füßling, Matthias
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, Gianluca
A1  - Eisenacher Glawion, Dorit
A1  - Glicenstein, Jean-François
A1  - Gottschall, D.
A1  - Grondin, Marie-Hélène
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, Gilles
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, Werner
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Jankowsky, David
A1  - Jankowsky, Felix
A1  - Jouvin, L.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzyński, Krzysztof
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, M.
A1  - Kruger, P. P.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lefaucheur, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lorentz, M.
A1  - Lopez-Coto, R.
A1  - Lypova, I.
A1  - Malyshev, D.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Padovani, M.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V.
A1  - Noel, A. Priyana
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Puehlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V.
A1  - Saito, S.
A1  - Sanchez, D. A.
A1  - Santangelo, Andrea
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schussler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I.
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Spanier, F.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
A1  - Cirelli, M.
A1  - Panci, P.
A1  - Sala, F.
A1  - Silk, J.
A1  - Taoso, M.
T1  - Searches for gamma-ray lines and 'pure WIMP' spectra from Dark Matter annihilations in dwarf galaxies with H.E.S.S.
JF  - Journal of cosmology and astroparticle physics
N2  - Dwarf spheroidal galaxies are among the most promising targets for detecting signals of Dark Matter (DM) annihilations. The H.E.S.S. experiment has observed five of these systems for a total of about 130 hours. The data are re-analyzed here, and, in the absence of any detected signals, are interpreted in terms of limits on the DM annihilation cross section. Two scenarios are considered: i) DM annihilation into mono-energetic gamma-rays and ii) DM in the form of pure WIMP multiplets that, annihilating into all electroweak bosons, produce a distinctive gamma-ray spectral shape with a high-energy peak at the DM mass and a lower-energy continuum. For case i), upper limits at 95% confidence level of about <sigma upsilon > less than or similar to 3 x 10(-25) cm(3) s(-1) are obtained in the mass range of 400 GeV to 1TeV. For case ii), the full spectral shape of the models is used and several excluded regions are identified, but the thermal masses of the candidates are not robustly ruled out.
KW  - dark matter detectors
KW  - dark matter experiments
KW  - dwarfs galaxies
KW  - gamma ray detectors
Y1  - 2018
U6  - https://doi.org/10.1088/1475-7516/2018/11/037
SN  - 1475-7516
IS  - 11
PB  - IOP Publishing Ltd. (Bristol)
CY  - Bristol
ER  -