TY - JOUR A1 - Meyer, M. F. A1 - Bacher, R. A1 - Roth, Kersten S. A1 - Beutner, D. A1 - Luers, J. C. T1 - Systematic analysis of the readability of patient information on websites of German nonuniversity ENT hospitals JF - HNO N2 - Besides their function as one of the main contact points, websites of hospitals serve as medical information portals. All patients should be able to understand medical information texts; regardless of their literacy skills and educational level. Online texts should thus have an appropriate structure to ease their comprehension. Patient information texts on every German nonuniversity ENT hospital website (n = 125) were systematically analysed. For ten different ENT topics a representative medical information text was extracted from each website. Using objective text parameters and five established readability indices, the texts were analysed in terms of their readability and structure. Furthermore, we stratified the analysis in relation to the hospital organisation system and geographical region in Germany. Texts from 142 internet sites could be used for the definite analysis. On average, texts consisted of 15 sentences and 237 words. Readability indices congruously showed that the analysed texts could generally only be understood by a well-educated or even academic reader. The majority of patient information texts on German hospital websites are difficult to understand for most patients. In order to fulfil their goal of adequately informing the general population about disease, therapeutic options and the particular focal points of the clinic, a revision of most medical texts on the websites of German ENT hospitals is recommended. KW - Patient information KW - Health literacy KW - Readability KW - Comprehensibility KW - Internet Y1 - 2014 U6 - https://doi.org/10.1007/s00106-013-2799-8 SN - 0017-6192 SN - 1433-0458 VL - 62 IS - 3 SP - 186 EP - + PB - Springer CY - New York ER - TY - JOUR A1 - Wang, Weijia A1 - Kaune, Gunar A1 - Perlich, Jan A1 - Paradakis, Christine M. A1 - Bivigou Koumba, Achille Mayelle A1 - Laschewsky, André A1 - Schlage, K. A1 - Röhlsberger, Ralf A1 - Roth, Stephan V. A1 - Cubitt, Robert A1 - Müller-Buschbaum, Peter T1 - Swelling and switching kinetics of gold coated end-capped poly(N-isopropylacrylamide) thin films N2 - Thin thermoresponsive hydrogel films of poly(N-isopropylacrylamide) end-capped with n-butyltrithiocarbonate(nbc- PNIPAM) oil si I icon supports with a gold layer on top, causing an asymmetric confinement, are investigated. For two different gold layer thicknesses (nominally 0.4 and 5 rim), the swelling and switching kinetics are probed with in situ neutron reflectivity. With a temperature jump from 23 to 40 degrees C the film is switched from a swollen into a collapsed state. For the thin gold layer this switching is faster as compared to the thick gold layer. The switching is a two-step process of water release and a subsequent structural relaxation. fit swelling and deswelling cycles, aging of the films is probed. After five cycles, the film exhibits enhanced water storage capacity. Grazing-incidence small-angle X-ray scattering (GISAXS) shows that these gold coated nbc-PNIPAM films do not age with respect to the inner structure but slightly roughen at the gold surface. As revealed by atomic force microscopy, the morphology of the gold layer is changed by the water uptake and release. Y1 - 2010 UR - http://pubs.acs.org/journal/mamobx U6 - https://doi.org/10.1021/Ma902637a SN - 0024-9297 ER - TY - JOUR A1 - Ellis, S. C. A1 - Bland-Hawthorn, Joss A1 - Lawrence, J. A1 - Horton, A. J. A1 - Trinh, C. A1 - Leon-Saval, S. G. A1 - Shortridge, K. A1 - Bryant, J. A1 - Case, S. A1 - Colless, M. A1 - Couch, W. A1 - Freeman, K. A1 - Gers, L. A1 - Glazebrook, K. A1 - Haynes, R. A1 - Lee, S. A1 - Löhmannsröben, Hans-Gerd A1 - O'Byrne, J. A1 - Miziarski, S. A1 - Roth, M. A1 - Schmidt, B. A1 - Tinney, C. G. A1 - Zheng, J. T1 - Suppression of the near-infrared OH night-sky lines with fibre Bragg gratings - first results JF - Monthly notices of the Royal Astronomical Society N2 - The background noise between 1 and 1.8 ?mu m in ground-based instruments is dominated by atmospheric emission from hydroxyl molecules. We have built and commissioned a new instrument, the Gemini Near-infrared OH Suppression Integral Field Unit (IFU) System (GNOSIS), which suppresses 103 OH doublets between 1.47 and 1.7?mu m by a factor of 1000 with a resolving power of 10?000. We present the first results from the commissioning of GNOSIS using the IRIS2 spectrograph at the Anglo-Australian Telescope. We present measurements of sensitivity, background and throughput. The combined throughput of the GNOSIS fore-optics, grating unit and relay optics is 36?per cent, but this could be improved to 46?per cent with a more optimal design. We measure strong suppression of the OH lines, confirming that OH suppression with fibre Bragg gratings will be a powerful technology for low-resolution spectroscopy. The integrated OH suppressed background between 1.5 and 1.7 mu m is reduced by a factor of 9 compared to a control spectrum using the same system without suppression. The potential of low-resolution OH-suppressed spectroscopy is illustrated with example observations of Seyfert galaxies and a low-mass star. The GNOSIS background is dominated by detector dark current below 1.67 mu m and by thermal emission above 1.67 mu m. After subtracting these, we detect an unidentified residual interline component of 860 +/- 210 photons s-1 m-2?arcsec-2?mu m-1, comparable to previous measurements. This component is equally bright in the suppressed and control spectra. We have investigated the possible source of the interline component, but were unable to discriminate between a possible instrumental artefact and intrinsic atmospheric emission. Resolving the source of this emission is crucial for the design of fully optimized OH suppression spectrographs. The next-generation OH suppression spectrograph will be focused on resolving the source of the interline component, taking advantage of better optimization for a fibre Bragg grating feed incorporating refinements of design based on our findings from GNOSIS. We quantify the necessary improvements for an optimal OH suppressing fibre spectrograph design. KW - atmospheric effects KW - instrumentation: miscellaneous KW - infrared: general Y1 - 2012 U6 - https://doi.org/10.1111/j.1365-2966.2012.21602.x SN - 0035-8711 VL - 425 IS - 3 SP - 1682 EP - 1695 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Zajnulina, Marina A1 - Böhm, Michael A1 - Blow, K. A1 - Rieznik, A. A. A1 - Giannone, Domenico A1 - Haynes, Roger A1 - Roth, Martin M. T1 - Soliton radiation beat analysis of optical pulses generated from two continuous-wave lasers JF - Chaos : an interdisciplinary journal of nonlinear science N2 - We propose a fibre-based approach for generation of optical frequency combs (OFCs) with the aim of calibration of astronomical spectrographs in the low and medium-resolution range. This approach includes two steps: in the first step, an appropriate state of optical pulses is generated and subsequently moulded in the second step delivering the desired OFC. More precisely, the first step is realised by injection of two continuous-wave (CW) lasers into a conventional single-mode fibre, whereas the second step generates a broad OFC by using the optical solitons generated in step one as initial condition. We investigate the conversion of a bichromatic input wave produced by two initial CW lasers into a train of optical solitons, which happens in the fibre used as step one. Especially, we are interested in the soliton content of the pulses created in this fibre. For that, we study different initial conditions (a single cosine-hump, an Akhmediev breather, and a deeply modulated bichromatic wave) by means of soliton radiation beat analysis and compare the results to draw conclusion about the soliton content of the state generated in the first step. In case of a deeply modulated bichromatic wave, we observed the formation of a collective soliton crystal for low input powers and the appearance of separated solitons for high input powers. An intermediate state showing the features of both, the soliton crystal and the separated solitons, turned out to be most suitable for the generation of OFC for the purpose of calibration of astronomical spectrographs. Y1 - 2015 U6 - https://doi.org/10.1063/1.4930316 SN - 1054-1500 SN - 1089-7682 VL - 25 IS - 10 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Muster, Sina A1 - Riley, William J. A1 - Roth, Kurt A1 - Langer, Moritz A1 - Aleina, Fabio Cresto A1 - Koven, Charles D. A1 - Lange, Stephan A1 - Bartsch, Annett A1 - Grosse, Guido A1 - Wilson, Cathy J. A1 - Jones, Benjamin M. A1 - Boike, Julia T1 - Size distributions of arctic waterbodies reveal consistent relations in their statistical moments in space and time JF - Frontiers in Earth Science N2 - Arctic lowlands are characterized by large numbers of small waterbodies, which are known to affect surface energy budgets and the global carbon cycle. Statistical analysis of their size distributions has been hindered by the shortage of observations at sufficiently high spatial resolutions. This situation has now changed with the high-resolution (<5 m) circum-Arctic Permafrost Region Pond and Lake (PeRL) database recently becoming available. We have used this database to make the first consistent, high-resolution estimation of Arctic waterbody size distributions, with surface areas ranging from 0.0001 km(2) (100 m(2)) to 1 km(2). We found that the size distributions varied greatly across the thirty study regions investigated and that there was no single universal size distribution function (including power-law distribution functions) appropriate across all of the study regions. We did, however, find close relationships between the statistical moments (mean, variance, and skewness) of the waterbody size distributions from different study regions. Specifically, we found that the spatial variance increased linearly with mean waterbody size (R-2 = 0.97, p < 2.2e-16) and that the skewness decreased approximately hyperbolically. We have demonstrated that these relationships (1) hold across the 30 Arctic study regions covering a variety of (bio)climatic and permafrost zones, (2) hold over time in two of these study regions for which multi-decadal satellite imagery is available, and (3) can be reproduced by simulating rising water levels in a high-resolution digital elevation model. The consistent spatial and temporal relationships between the statistical moments of the waterbody size distributions underscore the dominance of topographic controls in lowland permafrost areas. These results provide motivation for further analyses of the factors involved in waterbody development and spatial distribution and for investigations into the possibility of using statistical moments to predict future hydrologic dynamics in the Arctic. KW - permafrost KW - hydrology KW - waterbodies KW - size distribution KW - thermokarst KW - statistical moments KW - ponds KW - lakes Y1 - 2019 U6 - https://doi.org/10.3389/feart.2019.00005 SN - 2296-6463 VL - 7 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Bernardi, Rafael L. A1 - Berdja, Amokrane A1 - Dani Guzman, Christian A1 - Torres-Torriti, Miguel A1 - Roth, Martin M. T1 - Restoration of images with a spatially varying PSF of the T80-S telescope optical model using neural networks JF - Monthly notices of the Royal Astronomical Society N2 - Most image restoration methods in astronomy rely upon probabilistic tools that infer the best solution for a deconvolution problem. They achieve good performances when the point spread function (PSF) is spatially invariant in the image plane. However, this condition is not always satisfied in real optical systems. We propose a new method for the restoration of images affected by static and anisotropic aberrations using Deep Neural Networks that can be directly applied to sky images. The network is trained using simulated sky images corresponding to the T80-S Telescope optical model, a 80-cm survey imager at Cerro Tololo (Chile), which are synthesized using a Zernike polynomial representation of the optical system. Once trained, the network can be used directly on sky images, outputting a corrected version of the image that has a constant and known PSF across its field of view. The method is to be tested on the T80-S Telescope. We present the method and results on synthetic data. KW - methods: statistical KW - techniques: image processing Y1 - 2021 U6 - https://doi.org/10.1093/mnras/stab3400 SN - 0035-8711 SN - 1365-2966 VL - 510 IS - 3 SP - 4284 EP - 4294 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Schmaelzlin, Elmar A1 - Moralejo, Benito A1 - Rutowska, Monika A1 - Monreal-Ibero, Ana A1 - Sandin, Christer A1 - Tarcea, Nicolae A1 - Popp, Juergen A1 - Roth, Martin M. T1 - Raman imaging with a fiber-coupled multichannel spectrograph JF - Sensors N2 - Until now, spatially resolved Raman Spectroscopy has required to scan a sample under investigation in a time-consuming step-by-step procedure. Here, we present a technique that allows the capture of an entire Raman image with only one single exposure. The Raman scattering arising from the sample was collected with a fiber-coupled high-performance astronomy spectrograph. The probe head consisting of an array of 20 x 20 multimode fibers was linked to the camera port of a microscope. To demonstrate the high potential of this new concept, Raman images of reference samples were recorded. Entire chemical maps were received without the need for a scanning procedure. KW - multichannel Raman spectroscopy KW - astronomy spectrograph KW - optical fiber bundle KW - Raman imaging Y1 - 2014 U6 - https://doi.org/10.3390/s141121968 SN - 1424-8220 VL - 14 IS - 11 SP - 21968 EP - 21980 PB - MDPI CY - Basel ER - TY - GEN A1 - Ellis, S. C. A1 - Bauer, S. A1 - Bacigalupo, C. A1 - Bland-Hawthorn, J. A1 - Bryant, J. J. A1 - Case, S. A1 - Content, R. A1 - Fechner, T. A1 - Giannone, D. A1 - Haynes, R. A1 - Hernandez, E. A1 - Horton, A. J. A1 - Klauser, U. A1 - Lawrence, J. S. A1 - Leon-Saval, S. G. A1 - Lindley, E. A1 - Löhmannsröben, Hans-Gerd A1 - Min, S. -S. A1 - Pai, N. A1 - Roth, M. A1 - Shortridge, K. A1 - Waller, L. A1 - Xavier, Pascal A1 - Zhelem, Ross T1 - PRAXIS: an OH suppression optimised near infrared spectrograph T2 - Ground-based and Airborne Instrumentation for Astronomy VII N2 - The problem of atmospheric emission from OH molecules is a long standing problem for near-infrared astronomy. PRAXIS is a unique spectrograph which is fed by fibres that remove the OH background and is optimised specifically to benefit from OH-Suppression. The OH suppression is achieved with fibre Bragg gratings, which were tested successfully on the GNOSIS instrument. PRAXIS uses the same fibre Bragg gratings as GNOSIS in its first implementation, and will exploit new, cheaper and more efficient, multicore fibre Bragg gratings in the second implementation. The OH lines are suppressed by a factor of similar to 1000, and the expected increase in the signal-to-noise in the interline regions compared to GNOSIS is a factor of similar to 9 with the GNOSIS gratings and a factor of similar to 17 with the new gratings. PRAXIS will enable the full exploitation of OH suppression for the first time, which was not achieved by GNOSIS (a retrofit to an existing instrument that was not OH-Suppression optimised) due to high thermal emission, low spectrograph transmission and detector noise. PRAXIS has extremely low thermal emission, through the cooling of all significantly emitting parts, including the fore-optics, the fibre Bragg gratings, a long length of fibre, and the fibre slit, and an optical design that minimises leaks of thermal emission from outside the spectrograph. PRAXIS has low detector noise through the use of a Hawaii-2RG detector, and a high throughput through a efficient VPH based spectrograph. PRAXIS will determine the absolute level of the interline continuum and enable observations of individual objects via an IFU. In this paper we give a status update and report on acceptance tests. KW - Near infrared KW - spectroscopy KW - OH suppression KW - astrophotonics KW - fibre Bragg gratings Y1 - 2018 SN - 978-1-5106-1958-6 U6 - https://doi.org/10.1117/12.2311898 SN - 0277-786X SN - 1996-756X VL - 10702 PB - SPIE-INT Soc Optical Engineering CY - Bellingham ER - TY - JOUR A1 - Abdo, A. A. A1 - Ackermann, Margit A1 - Ajello, M. A1 - Allafort, A. J. A1 - Baldini, L. A1 - Ballet, J. A1 - Barbiellini, G. A1 - Baring, M. G. A1 - Bastieri, D. A1 - Bellazzini, R. A1 - Berenji, B. A1 - Blandford, R. D. A1 - Bloom, E. D. A1 - Bonamente, E. A1 - Borgland, A. W. A1 - Bouvier, A. A1 - Brandt, T. J. A1 - Bregeon, Johan A1 - Brigida, M. A1 - Bruel, P. A1 - Buehler, R. A1 - Buson, S. A1 - Caliandro, G. A. A1 - Cameron, R. A. A1 - Caraveo, P. A. A1 - Casandjian, J. M. A1 - Cecchi, C. A1 - Chaty, S. A1 - Chekhtman, A. A1 - Cheung, C. C. A1 - Chiang, J. A1 - Cillis, A. N. A1 - Ciprini, S. A1 - Claus, R. A1 - Cohen-Tanugi, J. A1 - Conrad, Jan A1 - Corbel, S. A1 - Cutini, S. A1 - de Angelis, A. A1 - de Palma, F. A1 - Dermer, C. D. A1 - Digel, S. W. A1 - do Couto e Silva, E. A1 - Drell, P. S. A1 - Drlica-Wagner, A. A1 - Dubois, R. A1 - Dumora, D. A1 - Favuzzi, C. A1 - Ferrara, E. C. A1 - Fortin, P. A1 - Frailis, M. A1 - Fukazawa, Y. A1 - Fukui, Y. A1 - Funk, S. A1 - Fusco, P. A1 - Gargano, F. A1 - Gasparrini, D. A1 - Gehrels, N. A1 - Germani, S. A1 - Giglietto, N. A1 - Giordano, F. A1 - Giroletti, M. A1 - Glanzman, T. A1 - Godfrey, G. A1 - Grenier, I. A. A1 - Grondin, M. -H. A1 - Guiriec, S. A1 - Hadasch, D. A1 - Hanabata, Y. A1 - Harding, A. K. A1 - Hayashida, M. A1 - Hayashi, K. A1 - Hays, E. A1 - Horan, D. A1 - Jackson, M. S. A1 - Johannesson, G. A1 - Johnson, A. S. A1 - Kamae, T. A1 - Katagiri, H. A1 - Kataoka, J. A1 - Kerr, M. A1 - Knoedlseder, J. A1 - Kuss, M. A1 - Lande, J. A1 - Latronico, L. A1 - Lee, S. -H. A1 - Lemoine-Goumard, M. A1 - Longo, F. A1 - Loparco, F. A1 - Lovellette, M. N. A1 - Lubrano, P. A1 - Madejski, G. M. A1 - Makeev, A. A1 - Mazziotta, Mario Nicola A1 - McEnery, J. E. A1 - Michelson, P. F. A1 - Mignani, R. P. A1 - Mitthumsiri, W. A1 - Mizuno, T. A1 - Moiseev, A. A. A1 - Monte, C. A1 - Monzani, M. E. A1 - Morselli, A. A1 - Moskalenko, I. V. A1 - Murgia, S. A1 - Naumann-Godo, M. A1 - Nolan, P. L. A1 - Norris, J. P. A1 - Nuss, E. A1 - Ohsugi, T. A1 - Okumura, A. A1 - Orlando, E. A1 - Ormes, J. F. A1 - Paneque, D. A1 - Parent, D. A1 - Pelassa, V. A1 - Pesce-Rollins, M. A1 - Pierbattista, M. A1 - Piron, F. A1 - Pohl, Martin A1 - Porter, T. A. A1 - Raino, S. A1 - Rando, R. A1 - Razzano, M. A1 - Reimer, O. A1 - Reposeur, T. A1 - Ritz, S. A1 - Romani, R. W. A1 - Roth, M. A1 - Sadrozinski, H. F. -W. A1 - Parkinson, P. M. Saz A1 - Sgro, C. A1 - Smith, D. A. A1 - Smith, P. D. A1 - Spandre, G. A1 - Spinelli, P. A1 - Strickman, M. S. A1 - Tajima, H. A1 - Takahashi, H. A1 - Takahashi, T. A1 - Tanaka, T. A1 - Thayer, J. G. A1 - Thayer, J. B. A1 - Thompson, D. J. A1 - Tibaldo, L. A1 - Tibolla, O. A1 - Torres, D. F. A1 - Tosti, G. A1 - Tramacere, A. A1 - Troja, E. A1 - Uchiyama, Y. A1 - Vandenbroucke, J. A1 - Vasileiou, V. A1 - Vianello, G. A1 - Vilchez, N. A1 - Vitale, V. A1 - Waite, A. P. A1 - Wang, P. A1 - Winer, B. L. A1 - Wood, K. S. A1 - Yamamoto, H. A1 - Yamazaki, R. A1 - Yang, Z. A1 - Ziegler, M. T1 - Observations of the young supernova remnant RX J1713.7-3946 with the fermi large area telescope JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We present observations of the young supernova remnant (SNR) RX J1713.7-3946 with the Fermi Large Area Telescope (LAT). We clearly detect a source positionally coincident with the SNR. The source is extended with a best-fit extension of 0 degrees.55 +/- 0 degrees.04 matching the size of the non-thermal X-ray and TeV gamma-ray emission from the remnant. The positional coincidence and the matching extended emission allow us to identify the LAT source with SNR RX J1713.7-3946. The spectrum of the source can be described by a very hard power law with a photon index of Gamma = 1.5 +/- 0.1 that coincides in normalization with the steeper H. E. S. S.-detected gamma-ray spectrum at higher energies. The broadband gamma-ray emission is consistent with a leptonic origin as the dominant mechanism for the gamma-ray emission. KW - acceleration of particles KW - gamma rays: general KW - gamma rays: ISM KW - ISM: individual objects (RX J1713.7-3946) KW - ISM: supernova remnants KW - radiation mechanisms: non-thermal Y1 - 2011 U6 - https://doi.org/10.1088/0004-637X/734/1/28 SN - 0004-637X VL - 734 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Schmälzlin, Elmar Gerd A1 - Moralejo, Benito A1 - Gersonde, Ingo A1 - Schleusener, Johannes A1 - Darvin, Maxim E. A1 - Thiede, Gisela A1 - Roth, Martin M. T1 - Nonscanning large-area Raman imaging for ex vivo/in vivo skin cancer discrimination JF - Journal of biomedical optics N2 - Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique of integral field spectroscopy (IFS) from astronomy to Raman imaging, it becomes possible to record entire Raman images quickly within a single exposure, without the need for a tedious scanning procedure. An IFS-based Raman imaging setup is presented, which is capable of measuring skin ex vivo or in vivo. It is demonstrated how Raman images of healthy and cancerous skin biopsies were recorded and analyzed. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. KW - Raman spectroscopy KW - cancer diagnosis KW - Raman imaging KW - multichannel KW - astronomy KW - epidermis KW - dermis Y1 - 2018 U6 - https://doi.org/10.1117/1.JBO.23.10.105001 SN - 1083-3668 SN - 1560-2281 VL - 23 IS - 10 PB - SPIE CY - Bellingham ER -