TY  - JOUR
A1  - Hoie, Lars H.
A1  - Morgenstern, E. C. A.
A1  - Grünwald, Jörg
A1  - Graubaum, Hans-Joachim
A1  - Busch, R.
A1  - Luder, W.
A1  - Zunft, Hans-Joachim Franz
T1  - A double-blind placebo-controlled clinical trial compares the cholesterollowering effects of two different soy protein preparations in hypercholesterolemic subjects
N2  - Background Soy protein is effective in lowering plasma cholesterol, LDL cholesterol and triglyceride concentrations. It has not been conclusively answered, whether and to what extent other soy constituents may also contribute to this effect. Objective To investigate the change in blood lipid levels after application of two soy-based supplements containing soy protein either without (SuproSoy(R)) or with (Abacor(R)) soy fiber and phospholipids in a randomized placebo-controlled triple-armed study. Methods 121 hypercholesterolemic adults ( 66 females, 55 males) were recruited and randomly assigned to one of three treatments. Over 8 weeks they received daily either 25 g soy protein ( as a component of the supplements Abacor(R) or SuproSoy(R)) or 25 g milk protein ( as a component of placebo). Serum lipids were measured at baseline and after 4, 6 and 8 weeks. Results After 8 weeks of supplementation total cholesterol levels were reduced by 8.0 +/- 9.6% (Abacor(R)) and 3.4 +/- 8.3% (SuproSoy(R)); LDL cholesterol levels by 9.7 +/- 11.7% ( Abacor(R)) and 5.4 +/- 11.6% ( SuproSoy(R)); and Apolipoprotein B levels by 6.9 +/- 14.6% (Abacor(R)) and 4.0 +/- 12.4 % (SuproSoy(R)). Serum levels of HDL cholesterol and triglycerides remained unchanged. Conclusions A preparation combining isolated soy protein with soy fibers and phospholipids showed twice the lipid-lowering effect of a preparation containing isolated soy protein alone. Therefore, such soy-based supplements can be useful in reducing the cardiovascular risk
Y1  - 2005
SN  - 1436-6207
ER  - 
TY  - JOUR
A1  - Graubaum, Hans-Joachim
A1  - Luder, W.
A1  - Zunft, Hans-Joachim Franz
T1  - A new isolated soy protein with high levels of nondenaturated protein shows twice the cholesterol-lowering effect of a commercial isolated soy protein
Y1  - 2004
SN  - 0022-3166
ER  - 
TY  - JOUR
A1  - Hoie, Lars H.
A1  - Morgenstern, E. C. A.
A1  - Grünwald, Jörg
A1  - Graubaum, Hans-Joachim
A1  - Luder, W.
A1  - Zunft, Hans-Joachim Franz
T1  - Combining soy protein with phospholipids and fiber doubles the lipid-lowering effects compared with soy protein alone
Y1  - 2004
SN  - 0022-3166
ER  -