TY - JOUR A1 - Ribar, Anita A1 - Huber, Stefan E. A1 - Smialek, Malgorzata A. A1 - Tanzer, Katrin A1 - Neustetter, Michael A1 - Schürmann, Robin A1 - Bald, Ilko A1 - Denifl, Stephan T1 - Hydroperoxyl radical and formic acid formation from common DNA stabilizers upon low energy electron attachment JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - 2-Amino-2-(hydroxymethyl)-1,3-propanediol (TRIS) and ethylenediaminetetraacetic acid ( EDTA) are key components of biological buffers and are frequently used as DNA stabilizers in irradiation studies. Such surface or liquid phase studies are done with the aim to understand the fundamental mechanisms of DNA radiation damage and to improve cancer radiotherapy. When ionizing radiation is used, abundant secondary electrons are formed during the irradiation process, which are able to attach to the molecular compounds present on the surface. In the present study we experimentally investigate low energy electron attachment to TRIS and methyliminodiacetic acid ( MIDA), an analogue of EDTA, supported by quantum chemical calculations. The most prominent dissociation channel for TRIS is through hydroperoxyl radical formation, whereas the dissociation of MIDA results in the formation of formic and acetic acid. These compounds are well-known to cause DNA modifications, like strand breaks. The present results indicate that buffer compounds may not have an exclusive protecting effect on DNA as suggested previously. Y1 - 2018 U6 - https://doi.org/10.1039/c7cp07697e SN - 1463-9076 SN - 1463-9084 VL - 20 IS - 8 SP - 5578 EP - 5585 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Abramowicz, Isidoro A1 - Arnold, Rafael A1 - Drori, Itamar A1 - Haußig, Hans-Michael A1 - Huber, Jasmina A1 - Katz, Daniel S. A1 - Keßler, Katrin A1 - Kleinecke, Ulrike A1 - Knufinke, Ulrich A1 - Przystawik, Mirko A1 - Nemtsov, Jascha A1 - Rebiger, Bill A1 - Ries, Rotraud A1 - Salzer, Dorothea M. A1 - Schirrmeister, Sebastian A1 - Stellmacher, Martha ED - Denz, Rebekka ED - Salzer, Dorothea M. T1 - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. = 'Ein Gebet ohne Gesang ist wie ein Körper ohne Seele.' : Aspekte der synagogalen Musik N2 - Die Zeitschrift möchte die fruchtbare und facettenreiche Kultur des Judentums sowie seine Berührungspunkte zur Umwelt in den unterschiedlichen Bereichen dokumentieren. Daneben dient die Zeitschrift als Forum zur Positionierung der Fächer Jüdische Studien und Judaistik innerhalb des wissenschaftlichen Diskurses sowie zur Diskussion ihrer historischen und gesellschaftlichen Verantwortung. N2 - The journal aims at documenting the fruitful and multifarious culture of Judaism as well as its relations to its environment within diverse areas of research. In addition, the journal is meant to promote Jewish Studies within academic discourse and discuss its historic and social responsibility. T3 - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. - 20 Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-70306 SN - 978-3-86956-290-2 SN - 1614-6492 SN - 1862-7684 IS - 20 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - RPRT A1 - Huber, Katrin A1 - Rolvering, Geske T1 - Public child care and mothers’ career trajectories T2 - CEPA Discussion Papers N2 - This paper studies the effect of public child care on mothers’ career trajectories. To this end, we combine county-level data on child care coverage with detailed individual-level information from the German social security records and exploit a set of German reforms leading to a substantial temporal and spatial variation in child care coverage for children under the age of three. We conduct an event study approach that investigates the labor market outcomes of mothers in the years around the birth of their first child. We thereby explore career trajectories, both in terms of quantity and quality of employment. We find that public child care improves maternal labor supply in the years immediately following childbirth. However, the results on quality-related outcomes suggest that the effect of child care provision does not reach far beyond pure employment effects. These results do not change for mothers with different ‘career costs of children’. T3 - CEPA Discussion Papers - 64 KW - child care KW - maternal employment KW - career costs of children KW - women’s careers Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-587310 SN - 2628-653X IS - 64 ER -