TY  - JOUR
A1  - Krylov, Andrey V.
A1  - Beissenhirtz, Moritz Karl
A1  - Adamzig, Holger
A1  - Scheller, Frieder W.
A1  - Lisdat, Fred
T1  - Thick-film electrodes for measurement of superoxide and hydrogen peroxide based on direct protein-electrode contacts
N2  - Cytochrome c was immobilized on screen-printed thick-film gold electrodes by a self-assembly approach using mixed monolayers of mercaptoundecanoic acid and mercaptoundecanol. Cyclic voltammetry revealed quasi-reversible electrochemical behavior of the covalently fixed protein with a formal potential of +10 mV vs. Ag/AgCl. Polarized at +150 mV vs. Ag/AgCl the electrode was found to be sensitive to superoxide radicals in the range 300-1200 nmol L-1. Compared with metal needle electrodes sensitivity and reproducibility could be improved and combined with the easiness of preparation. This allows the fabrication of disposable sensors for nanomolar superoxide concentrations. By changing the electrode potential the sensor can be switched from response to superoxide radicals to hydrogen peroxide-another reactive oxygen species. H2O2 sensitivity can be provided in the range 10-1000 mumol L-1 which makes the electrode suitable for oxidative stress studies
Y1  - 2004
ER  - 
TY  - BOOK
A1  - Barsch, Heiner
A1  - Carstensen, Ines
A1  - Geldmacher, Karl
A1  - Hering, Frank
A1  - Jeserigk, Holger
A1  - Knothe, Dieter
A1  - Saupe, Gabriele
A1  - Ziener, Karen
T1  - Entwicklung und Gestaltung von Erholungsgebieten in Bergbaufolgelandschaften der Niederlausitz
T3  - Potsdamer Geographische Forschungen - 17 
Y1  - 1999
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-53026
ER  - 
TY  - JOUR
A1  - Geldmacher, Karl
A1  - Preuß, Peter
A1  - Carstensen, Ines
A1  - Jeserigk, Holger
T1  - Erlebbare Rekultivierung
N2  - Erarbeitung eines Spontanentwurfs zur erlebbaren Rekultivierung von Bergbaulandschaften. Es erfolgt eine Darstellung von Anwendungsbeispielen(u.a. Radwegenetz, Wasserwanderweg Berlin-Lausitz)
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Arnold, Rafael
A1  - Boehlich, Sabine
A1  - Dallapiazza, Michael
A1  - Denz, Rebekka
A1  - Feinberg, Anat
A1  - Grözinger, Elvira
A1  - Grözinger, Karl E.
A1  - Heni, Clemens
A1  - Jütte, Daniel
A1  - Jütte, Robert
A1  - Jurewicz, Grażyna
A1  - Kamoshida, Satoko
A1  - Kerbel, Arturo
A1  - Kühn-Ludewig, Maria
A1  - Nath, Holger
A1  - Riemer, Nathanael
A1  - Rösch, Juliane
A1  - Rubin, Joel
A1  - Saß, Anne-Christin
A1  - Ueda, Kazuo
ED  - Denz, Rebekka
ED  - Dubrau, Alexander
ED  - Riemer, Nathanael
T1  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. = Jiddische Quellen
N2  - Wissenschaftliche Artikel: Sabine Boehlich “Nisters Nay-gayst. Der Schriftsteller als Zaddik” Juliane Rösch „Di berliner hobn nisht gegloybt zeyere oygn“. Das jiddischsprachige Theater GOSET und der Regisseur Alexander Granovsky Anne-Christin Saß „Wenn die Nazi-Verbrecher nach Hause kommen” – Dovid Eynhorns Berichte über die nationalsozialistischen Verbrechen im New Yorker Forverts 1940-1945 Rebekka Denz Der „Froyenvinkl“ : Die Frauenrubrik in der bundischen Tageszeitung „Naye Folkstsaytung“ Nathanael Riemer Some parallels of stories in Glikls of Hameln Zikhroynes Jiddisch aus aller Welt: Holger Nath The First Yiddish Summer Program in Birobidzhan (August 13-August 30, 2007) Satoko Kamoshida A woman and a language: In the case of a Yiddish speaker in Israel Arturo Kerbel “Dear brother! Where from are you coming?” A brief history of the Yiddish language and culture in Mexiko Kazuo Ueda Jiddischforschung in Japan Essay: Elvira Grözinger Die Deutsche Bahn und die Krux mit dem Gedenken Tagungsberichte: “Zwischenräume”. Jüdisch-christliche Lebenswelten unter venezianischer Herrschaft im späten Mittelalter und der frühen Neuzeit. Venedig, Deutsches Studienzentrum und Dipartimento di Studi Storici der Universität Ca’ Foscari, 5.9.-7.9. 2007. (Daniel Jütte) “Global Forum for Combating Antisemitism”, Israelisches Außenministerium, Jerusalem, 24.-25.2. 2008. (Clemens Heni) Rezensionen: Arno Herzig/Cay Rademacher (Hg.): Die Geschichte der Juden in Deutschland (Robert Jütte) Georg Bossong: Die Sepharden. Geschichte und Kultur der spanischen Juden (Rafael Arnold) Barbara Staudinger: Die jüdische Welt und die Wittelsbacher (Daniel Jütte) Leon Modena: Jüdische Riten, Sitten und Gebräuche. Hg., übersetzt und kommentiert von Rafael Arnold (Karl E. Grözinger) Kenneth Stow: An Image and Its Interpreters. Continuity in the Catholic-Jewish Encounter (Elvira Grözinger) Aldina Quintana Rodríguez: Geografía Lingüística del Judeoespañol. Estudio sincrónico y diacrónico (Rafael Arnold) Wolfgang Vogt: Moses Mendelssohns Beschreibung der Wirklichkeit menschlichen Erkennens (Grazyna Jurewicz) Stefan Müller-Doohm (Hg.): Adorno-Portraits. Erinnerungen von Zeitgenossen (Michael Dallapiazza) Andrea Löw: Juden im Getto Litzmannstadt. Lebensbedingungen, Selbstwahrnehmung, Verhalten. Die Chronik des Gettos Lodz/Litzmannstadt. Hg. v. Sascha Feuchert, Erwin Leibfried, Jörg Riecke (Maria Kühn-Ludewig) Eglè Bendikaitè: Sionistinis sajudis Lietuvoje. Litauisches Historisches Institut (Elvira Grözinger) Barbara Staudinger (Hg.): Von Bayern nach Erez Israel. Auf den Spuren jüdischer Volkskunst. From Bavaria to Eretz Israel. Tracing Jewish Folk Art (Anat Feinberg) Hugh Denman (Hg.): Isaac Bashevis Singer: His Work and His World (Elvira Grözinger) Annkatrin Dahm: Der Topos der Juden. Studien zur Geschichte des Antisemitismus im deutschsprachigen Musikschrifttum (Daniel Jütte) Max Peter Baumann/Tim Becker/Raphael Woebs (Hg.): Musik und Kultur im jüdischen Leben der Gegenwart (Joel E. Rubin)
T3  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. - 14 
Y1  - 2008
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-19179
SN  - 978-3-940793-41-6
SN  - 1862-7684
SN  - 1614-6492
IS  - 14
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - GEN
A1  - Lang, Judith
A1  - Bohn, Patrick
A1  - Bhat, Hilal
A1  - Jastrow, Holger
A1  - Walkenfort, Bernd
A1  - Cansiz, Feyza
A1  - Fink, Julian
A1  - Bauer, Michael
A1  - Schumacher, Fabian
A1  - Kleuser, Burkhard
A1  - Lang, Karl S.
T1  - Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
T2  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Macrophages have important protective functions during infection with herpes simplex virus type 1 (HSV-1). However, molecular mechanisms that restrict viral propagation and protect from severe disease are unclear. Here we show that macrophages take up HSV-1 via endocytosis and transport the virions into multivesicular bodies (MVBs). In MVBs, acid ceramidase (aCDase) converts ceramide into sphingosine and increases the formation of sphingosine-rich intraluminal vesicles (ILVs). Once HSV-1 particles reach MVBs, sphingosine-rich ILVs bind to HSV-1 particles, which restricts fusion with the limiting endosomal membrane and prevents cellular infection. Lack of aCDase in macrophage cultures or in Asah1(-/-) mice results in replication of HSV-1 and Asah1(-/-) mice die soon after systemic or intravaginal inoculation. The treatment of macrophages with sphingosine enhancing compounds blocks HSV-1 propagation, suggesting a therapeutic potential of this pathway. In conclusion, aCDase loads ILVs with sphingosine, which prevents HSV-1 capsids from penetrating into the cytosol.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1400 
KW  - immunology
KW  - infection
KW  - membrane fusion
KW  - phagocytosis
KW  - sphingolipids
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-515661
SN  - 1866-8372
IS  - 1
ER  - 
TY  - JOUR
A1  - Lang, Judith
A1  - Bohn, Patrick
A1  - Bhat, Hilal
A1  - Jastrow, Holger
A1  - Walkenfort, Bernd
A1  - Cansiz, Feyza
A1  - Fink, Julian
A1  - Bauer, Michael
A1  - Schumacher, Fabian
A1  - Kleuser, Burkhard
A1  - Lang, Karl S.
T1  - Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
JF  - Nature Communications
N2  - Macrophages have important protective functions during infection with herpes simplex virus type 1 (HSV-1). However, molecular mechanisms that restrict viral propagation and protect from severe disease are unclear. Here we show that macrophages take up HSV-1 via endocytosis and transport the virions into multivesicular bodies (MVBs). In MVBs, acid ceramidase (aCDase) converts ceramide into sphingosine and increases the formation of sphingosine-rich intraluminal vesicles (ILVs). Once HSV-1 particles reach MVBs, sphingosine-rich ILVs bind to HSV-1 particles, which restricts fusion with the limiting endosomal membrane and prevents cellular infection. Lack of aCDase in macrophage cultures or in Asah1(-/-) mice results in replication of HSV-1 and Asah1(-/-) mice die soon after systemic or intravaginal inoculation. The treatment of macrophages with sphingosine enhancing compounds blocks HSV-1 propagation, suggesting a therapeutic potential of this pathway. In conclusion, aCDase loads ILVs with sphingosine, which prevents HSV-1 capsids from penetrating into the cytosol.
KW  - immunology
KW  - infection
KW  - membrane fusion
KW  - phagocytosis
KW  - sphingolipids
Y1  - 2020
U6  - https://doi.org/10.1038/s41467-020-15072-8
SN  - 2041-1723
VL  - 11
IS  - 1
SP  - 1
EP  - 15
PB  - Nature Publishing Group UK
CY  - London
ER  - 
TY  - JOUR
A1  - Tittel, Jörg
A1  - Bork, Rudolf
A1  - Röpke, Björn
A1  - Geldmacher, Karl
A1  - Schnur, Tilo
A1  - Faust, Berno
A1  - Schaphoff, Sibyll
A1  - Dalchow, Claus
A1  - Woithe, Franka
A1  - Bronstert, Axel
A1  - Jeltsch, Florian
A1  - Jessel, Beate
A1  - Zschalich, Andrea
A1  - Rößling, Holger
A1  - Spindler, Joris
A1  - Gaedke, Ursula
A1  - Tielbörger, Katja
A1  - Kadmon, R.
A1  - Müller, J.
A1  - Bissinger, Vera
A1  - Weithoff, Guntram
A1  - Wallschläger, Hans-Dieter
A1  - Wiegleb, Gerhard
T1  - Umweltforschung für das Land Brandenburg
BT  - Projekt Ökologie und Naturschutz / Landschaftsplanung / Landschaftsentwicklung
JF  - Brandenburgische Umwelt-Berichte : BUB ; Schriftenreihe der Mathematisch-Naturwissenschaftlichen Fakultät der Universität Potsdam
N2  - BISSINGER, V.; TITTEL, J.: Process rates and growth limiting factors of planktonic algae (Chlamydomonas sp.) from extremely acidic (pH 2,5 - 3) mining lakes in Germany ; BORK, H.-R. et al.: Erodierte Autos und Brunnen in Oregon, USA ; BRONSTERT, A. et al.: Bewirtschaftunsmöglichkeiten im Einzugsgebiet der Havel ; JELTSCH, F. et al.: Beweidung als Degradationsfaktor in ariden und semiariden Weidesystemen ; JELTSCH, F. et al.: Entstehung und Bedeutung räumlicher Vegetationsstrukturen in Trockensavannen: Baum-Graskoexistenz und Artenvielfalt ; JESSEL, B. et al.: Bodenbewertung für Planungs- und Zulassungsverfahren in Brandenburg ; JESSEL, B.; ZSCHALICH, A.: Erarbeitung von Ausgleichs- und Ersatzmaßnahmen für die Wert- und Funktionselemente des Landschaftsbildes ; RÖßLING, H. et al.: Umsetzung von Ausgleichs- und Ersatzmaßnahmen beim Ausbau der Bundesautobahn A 9 ; SPINDLER, J.; GAEDKE, U.: Estimating production in plankton food webs from biomass size spectra and allometric relationships ; TIELBÖRGER, K. et al.: Sukzessionsprozesse in einem Sanddünengebiet nach Ausschluß von Beweidung ; TIELBÖRGER, K. et al.: Populationsdynamische Funktionen von Ausbreitung und Dormanz ; TIELBÖRGER, K. et al.: Raum-zeitliche Populationsdynamik von einjährigen Wüstenpflanzen ; TITTEL, J. et al.: Ressourcennutzung und -weitergabe im planktischen Nahrungsnetz eines extrem sauren (pH 2,7) Tagebausees ; WALLSCHLÄGER, D.; WIEGLEB, G.: Offenland-Management auf ehemaligen und in Nutzung befindlichen Truppenübungsplätzen im pleistozänen Flachland Nordostdeutschlands: Naturschutzfachliche Grundlagen und praktische Anwendungen ; WEITHOFF, G.; GAEDKE, U.: Planktische Räuber-Beute-Systeme: Experimentelle Untersuchung von ökologischen Synchronisationen
Y1  - 2000
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-3828
SN  - 1434-2375
SN  - 1611-9339
VL  - 8
SP  - 80
EP  - 134
ER  - 
TY  - GEN
A1  - Weber, Stephanie
A1  - Puta, Christian
A1  - Lesinski, Melanie
A1  - Gabriel, Brunhild
A1  - Steidten, Thomas
A1  - Bär, Karl-Jürgen
A1  - Herbsleb, Marco
A1  - Granacher, Urs
A1  - Gabriel, Holger H. W.
T1  - Symptoms of anxiety and depression in young athletes using the Hospital Anxiety and Depression Scale
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Elite young athletes have to cope with multiple psychological demands such as training volume, mental and physical fatigue, spatial separation of family and friends or time management problems may lead to reduced mental and physical recovery. While normative data regarding symptoms of anxiety and depression for the general population is available (Hinz and Brahler, 2011), hardly any information exists for adolescents in general and young athletes in particular. Therefore, the aim of this study was to assess overall symptoms of anxiety and depression in young athletes as well as possible sex differences. The survey was carried out within the scope of the study "Resistance Training in Young Athletes" (KINGS-Study). Between August 2015 and September 2016, 326 young athletes aged (mean +/- SD) 14.3 +/- 1.6 years completed the Hospital Anxiety and Depression Scale (HAD Scale). Regarding the analysis of age on the anxiety and depression subscales, age groups were classified as follows: late childhood (12-14 years) and late adolescence (15-18 years). The participating young athletes were recruited from Olympic weight lifting, handball, judo, track and field athletics, boxing, soccer, gymnastics, ice speed skating, volleyball, and rowing. Anxiety and depression scores were (mean +/- SD) 4.3 +/- 3.0 and 2.8 +/- 2.9, respectively. In the subscale anxiety, 22 cases (6.7%) showed subclinical scores and 11 cases (3.4%) showed clinical relevant score values. When analyzing the depression subscale, 31 cases (9.5%) showed subclinical score values and 12 cases (3.7%) showed clinically important values. No significant differences were found between male and female athletes (p >= 0.05). No statistically significant differences in the HADS scores were found between male athletes of late childhood and late adolescents (p >= 0.05). To the best of our knowledge, this is the first report describing questionnaire based indicators of symptoms of anxiety and depression in young athletes. Our data implies the need for sports medical as well as sports psychiatric support for young athletes. In addition, our results demonstrated that the chronological classification concerning age did not influence HAD Scale outcomes. Future research should focus on sports medical and sports psychiatric interventional approaches with the goal to prevent anxiety and depression as well as teaching coping strategies to young athletes.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 638 
KW  - youth athletes
KW  - anxiety
KW  - depression
KW  - gender differences
KW  - late childhood
KW  - adolescents
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-445602
SN  - 1866-8364
IS  - 638
ER  - 
TY  - JOUR
A1  - Weber, Stephanie
A1  - Puta, Christian
A1  - Lesinski, Melanie
A1  - Gabriel, Brunhild
A1  - Steidten, Thomas
A1  - Bär, Karl-Jürgen
A1  - Herbsleb, Marco
A1  - Granacher, Urs
A1  - Gabriel, Holger H. W.
T1  - Symptoms of anxiety and depression in young athletes using the hospital anxiety and depression scale
JF  - Frontiers in physiology
N2  - Elite young athletes have to cope with multiple psychological demands such as training volume, mental and physical fatigue, spatial separation of family and friends or time management problems may lead to reduced mental and physical recovery. While normative data regarding symptoms of anxiety and depression for the general population is available (Hinz and Brahler, 2011), hardly any information exists for adolescents in general and young athletes in particular. Therefore, the aim of this study was to assess overall symptoms of anxiety and depression in young athletes as well as possible sex differences. The survey was carried out within the scope of the study "Resistance Training in Young Athletes" (KINGS-Study). Between August 2015 and September 2016, 326 young athletes aged (mean +/- SD) 14.3 +/- 1.6 years completed the Hospital Anxiety and Depression Scale (HAD Scale). Regarding the analysis of age on the anxiety and depression subscales, age groups were classified as follows: late childhood (12-14 years) and late adolescence (15-18 years). The participating young athletes were recruited from Olympic weight lifting, handball, judo, track and field athletics, boxing, soccer, gymnastics, ice speed skating, volleyball, and rowing. Anxiety and depression scores were (mean +/- SD) 4.3 +/- 3.0 and 2.8 +/- 2.9, respectively. In the subscale anxiety, 22 cases (6.7%) showed subclinical scores and 11 cases (3.4%) showed clinical relevant score values. When analyzing the depression subscale, 31 cases (9.5%) showed subclinical score values and 12 cases (3.7%) showed clinically important values. No significant differences were found between male and female athletes (p >= 0.05). No statistically significant differences in the HADS scores were found between male athletes of late childhood and late adolescents (p >= 0.05). To the best of our knowledge, this is the first report describing questionnaire based indicators of symptoms of anxiety and depression in young athletes. Our data implies the need for sports medical as well as sports psychiatric support for young athletes. In addition, our results demonstrated that the chronological classification concerning age did not influence HAD Scale outcomes. Future research should focus on sports medical and sports psychiatric interventional approaches with the goal to prevent anxiety and depression as well as teaching coping strategies to young athletes.
KW  - youth athletes
KW  - anxiety
KW  - depression
KW  - gender differences
KW  - late childhood
KW  - adolescents
Y1  - 2018
U6  - https://doi.org/10.3389/fphys.2018.00182
SN  - 1664-042X
VL  - 9
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Dressler, Falko
A1  - Chiasserini, Carla Fabiana
A1  - Fitzek, Frank H. P.
A1  - Karl, Holger
A1  - Cigno, Renato Lo
A1  - Capone, Antonio
A1  - Casetti, Claudio
A1  - Malandrino, Francesco
A1  - Mancuso, Vincenzo
A1  - Klingler, Florian
A1  - Rizzo, Gianluca
T1  - V-Edge
BT  - virtual edge computing as an enabler for novel microservices and cooperative computing
JF  - IEEE network
N2  - As we move from 5G to 6G, edge computing is one of the concepts that needs revisiting. Its core idea is still intriguing: Instead of sending all data and tasks from an end user's device to the cloud, possibly covering thousands of kilometers and introducing delays lower-bounded by propagation speed, edge servers deployed in close proximity to the user (e.g., at some base station) serve as proxy for the cloud. This is particularly interesting for upcoming machine-learning-based intelligent services, which require substantial computational and networking performance for continuous model training. However, this promising idea is hampered by the limited number of such edge servers. In this article, we discuss a way forward, namely the V-Edge concept. V-Edge helps bridge the gap between cloud, edge, and fog by virtualizing all available resources including the end users' devices and making these resources widely available. Thus, V-Edge acts as an enabler for novel microservices as well as cooperative computing solutions in next-generation networks. We introduce the general V-Edge architecture, and we characterize some of the key research challenges to overcome in order to enable wide-spread and intelligent edge services.
KW  - Training
KW  - Performance evaluation
KW  - Cloud computing
KW  - Microservice
KW  - architectures
KW  - Computer architecture
KW  - Delays
KW  - Servers
Y1  - 2022
U6  - https://doi.org/10.1109/MNET.001.2100491
SN  - 0890-8044
SN  - 1558-156X
VL  - 36
IS  - 3
SP  - 24
EP  - 31
PB  - Inst. of Electr. and Electronics Engineers
CY  - Piscataway
ER  -