TY  - JOUR
A1  - Aarts, Alexander A.
A1  - Anderson, Joanna E.
A1  - Anderson, Christopher J.
A1  - Attridge, Peter R.
A1  - Attwood, Angela
A1  - Axt, Jordan
A1  - Babel, Molly
A1  - Bahnik, Stepan
A1  - Baranski, Erica
A1  - Barnett-Cowan, Michael
A1  - Bartmess, Elizabeth
A1  - Beer, Jennifer
A1  - Bell, Raoul
A1  - Bentley, Heather
A1  - Beyan, Leah
A1  - Binion, Grace
A1  - Borsboom, Denny
A1  - Bosch, Annick
A1  - Bosco, Frank A.
A1  - Bowman, Sara D.
A1  - Brandt, Mark J.
A1  - Braswell, Erin
A1  - Brohmer, Hilmar
A1  - Brown, Benjamin T.
A1  - Brown, Kristina
A1  - Bruening, Jovita
A1  - Calhoun-Sauls, Ann
A1  - Callahan, Shannon P.
A1  - Chagnon, Elizabeth
A1  - Chandler, Jesse
A1  - Chartier, Christopher R.
A1  - Cheung, Felix
A1  - Christopherson, Cody D.
A1  - Cillessen, Linda
A1  - Clay, Russ
A1  - Cleary, Hayley
A1  - Cloud, Mark D.
A1  - Cohn, Michael
A1  - Cohoon, Johanna
A1  - Columbus, Simon
A1  - Cordes, Andreas
A1  - Costantini, Giulio
A1  - Alvarez, Leslie D. Cramblet
A1  - Cremata, Ed
A1  - Crusius, Jan
A1  - DeCoster, Jamie
A1  - DeGaetano, Michelle A.
A1  - Della Penna, Nicolas
A1  - den Bezemer, Bobby
A1  - Deserno, Marie K.
A1  - Devitt, Olivia
A1  - Dewitte, Laura
A1  - Dobolyi, David G.
A1  - Dodson, Geneva T.
A1  - Donnellan, M. Brent
A1  - Donohue, Ryan
A1  - Dore, Rebecca A.
A1  - Dorrough, Angela
A1  - Dreber, Anna
A1  - Dugas, Michelle
A1  - Dunn, Elizabeth W.
A1  - Easey, Kayleigh
A1  - Eboigbe, Sylvia
A1  - Eggleston, Casey
A1  - Embley, Jo
A1  - Epskamp, Sacha
A1  - Errington, Timothy M.
A1  - Estel, Vivien
A1  - Farach, Frank J.
A1  - Feather, Jenelle
A1  - Fedor, Anna
A1  - Fernandez-Castilla, Belen
A1  - Fiedler, Susann
A1  - Field, James G.
A1  - Fitneva, Stanka A.
A1  - Flagan, Taru
A1  - Forest, Amanda L.
A1  - Forsell, Eskil
A1  - Foster, Joshua D.
A1  - Frank, Michael C.
A1  - Frazier, Rebecca S.
A1  - Fuchs, Heather
A1  - Gable, Philip
A1  - Galak, Jeff
A1  - Galliani, Elisa Maria
A1  - Gampa, Anup
A1  - Garcia, Sara
A1  - Gazarian, Douglas
A1  - Gilbert, Elizabeth
A1  - Giner-Sorolla, Roger
A1  - Glöckner, Andreas
A1  - Göllner, Lars
A1  - Goh, Jin X.
A1  - Goldberg, Rebecca
A1  - Goodbourn, Patrick T.
A1  - Gordon-McKeon, Shauna
A1  - Gorges, Bryan
A1  - Gorges, Jessie
A1  - Goss, Justin
A1  - Graham, Jesse
A1  - Grange, James A.
A1  - Gray, Jeremy
A1  - Hartgerink, Chris
A1  - Hartshorne, Joshua
A1  - Hasselman, Fred
A1  - Hayes, Timothy
A1  - Heikensten, Emma
A1  - Henninger, Felix
A1  - Hodsoll, John
A1  - Holubar, Taylor
A1  - Hoogendoorn, Gea
A1  - Humphries, Denise J.
A1  - Hung, Cathy O. -Y.
A1  - Immelman, Nathali
A1  - Irsik, Vanessa C.
A1  - Jahn, Georg
A1  - Jaekel, Frank
A1  - Jekel, Marc
A1  - Johannesson, Magnus
A1  - Johnson, Larissa G.
A1  - Johnson, David J.
A1  - Johnson, Kate M.
A1  - Johnston, William J.
A1  - Jonas, Kai
A1  - Joy-Gaba, Jennifer A.
A1  - Kappes, Heather Barry
A1  - Kelso, Kim
A1  - Kidwell, Mallory C.
A1  - Kim, Seung Kyung
A1  - Kirkhart, Matthew
A1  - Kleinberg, Bennett
A1  - Knezevic, Goran
A1  - Kolorz, Franziska Maria
A1  - Kossakowski, Jolanda J.
A1  - Krause, Robert Wilhelm
A1  - Krijnen, Job
A1  - Kuhlmann, Tim
A1  - Kunkels, Yoram K.
A1  - Kyc, Megan M.
A1  - Lai, Calvin K.
A1  - Laique, Aamir
A1  - Lakens, Daniel
A1  - Lane, Kristin A.
A1  - Lassetter, Bethany
A1  - Lazarevic, Ljiljana B.
A1  - LeBel, Etienne P.
A1  - Lee, Key Jung
A1  - Lee, Minha
A1  - Lemm, Kristi
A1  - Levitan, Carmel A.
A1  - Lewis, Melissa
A1  - Lin, Lin
A1  - Lin, Stephanie
A1  - Lippold, Matthias
A1  - Loureiro, Darren
A1  - Luteijn, Ilse
A1  - Mackinnon, Sean
A1  - Mainard, Heather N.
A1  - Marigold, Denise C.
A1  - Martin, Daniel P.
A1  - Martinez, Tylar
A1  - Masicampo, E. J.
A1  - Matacotta, Josh
A1  - Mathur, Maya
A1  - May, Michael
A1  - Mechin, Nicole
A1  - Mehta, Pranjal
A1  - Meixner, Johannes
A1  - Melinger, Alissa
A1  - Miller, Jeremy K.
A1  - Miller, Mallorie
A1  - Moore, Katherine
A1  - Möschl, Marcus
A1  - Motyl, Matt
A1  - Müller, Stephanie M.
A1  - Munafo, Marcus
A1  - Neijenhuijs, Koen I.
A1  - Nervi, Taylor
A1  - Nicolas, Gandalf
A1  - Nilsonne, Gustav
A1  - Nosek, Brian A.
A1  - Nuijten, Michele B.
A1  - Olsson, Catherine
A1  - Osborne, Colleen
A1  - Ostkamp, Lutz
A1  - Pavel, Misha
A1  - Penton-Voak, Ian S.
A1  - Perna, Olivia
A1  - Pernet, Cyril
A1  - Perugini, Marco
A1  - Pipitone, R. Nathan
A1  - Pitts, Michael
A1  - Plessow, Franziska
A1  - Prenoveau, Jason M.
A1  - Rahal, Rima-Maria
A1  - Ratliff, Kate A.
A1  - Reinhard, David
A1  - Renkewitz, Frank
A1  - Ricker, Ashley A.
A1  - Rigney, Anastasia
A1  - Rivers, Andrew M.
A1  - Roebke, Mark
A1  - Rutchick, Abraham M.
A1  - Ryan, Robert S.
A1  - Sahin, Onur
A1  - Saide, Anondah
A1  - Sandstrom, Gillian M.
A1  - Santos, David
A1  - Saxe, Rebecca
A1  - Schlegelmilch, Rene
A1  - Schmidt, Kathleen
A1  - Scholz, Sabine
A1  - Seibel, Larissa
A1  - Selterman, Dylan Faulkner
A1  - Shaki, Samuel
A1  - Simpson, William B.
A1  - Sinclair, H. Colleen
A1  - Skorinko, Jeanine L. M.
A1  - Slowik, Agnieszka
A1  - Snyder, Joel S.
A1  - Soderberg, Courtney
A1  - Sonnleitner, Carina
A1  - Spencer, Nick
A1  - Spies, Jeffrey R.
A1  - Steegen, Sara
A1  - Stieger, Stefan
A1  - Strohminger, Nina
A1  - Sullivan, Gavin B.
A1  - Talhelm, Thomas
A1  - Tapia, Megan
A1  - te Dorsthorst, Anniek
A1  - Thomae, Manuela
A1  - Thomas, Sarah L.
A1  - Tio, Pia
A1  - Traets, Frits
A1  - Tsang, Steve
A1  - Tuerlinckx, Francis
A1  - Turchan, Paul
A1  - Valasek, Milan
A1  - Van Aert, Robbie
A1  - van Assen, Marcel
A1  - van Bork, Riet
A1  - van de Ven, Mathijs
A1  - van den Bergh, Don
A1  - van der Hulst, Marije
A1  - van Dooren, Roel
A1  - van Doorn, Johnny
A1  - van Renswoude, Daan R.
A1  - van Rijn, Hedderik
A1  - Vanpaemel, Wolf
A1  - Echeverria, Alejandro Vasquez
A1  - Vazquez, Melissa
A1  - Velez, Natalia
A1  - Vermue, Marieke
A1  - Verschoor, Mark
A1  - Vianello, Michelangelo
A1  - Voracek, Martin
A1  - Vuu, Gina
A1  - Wagenmakers, Eric-Jan
A1  - Weerdmeester, Joanneke
A1  - Welsh, Ashlee
A1  - Westgate, Erin C.
A1  - Wissink, Joeri
A1  - Wood, Michael
A1  - Woods, Andy
A1  - Wright, Emily
A1  - Wu, Sining
A1  - Zeelenberg, Marcel
A1  - Zuni, Kellylynn
T1  - Estimating the reproducibility of psychological science
JF  - Science
N2  - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.
Y1  - 2015
U6  - https://doi.org/10.1126/science.aac4716
SN  - 1095-9203
SN  - 0036-8075
VL  - 349
IS  - 6251
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - JOUR
A1  - Warrington, Nicole
A1  - Beaumont, Robin
A1  - Horikoshi, Momoko
A1  - Day, Felix R.
A1  - Helgeland, Øyvind
A1  - Laurin, Charles
A1  - Bacelis, Jonas
A1  - Peng, Shouneng
A1  - Hao, Ke
A1  - Feenstra, Bjarke
A1  - Wood, Andrew R.
A1  - Mahajan, Anubha
A1  - Tyrrell, Jessica
A1  - Robertson, Neil R.
A1  - Rayner, N. William
A1  - Qiao, Zhen
A1  - Moen, Gunn-Helen
A1  - Vaudel, Marc
A1  - Marsit, Carmen
A1  - Chen, Jia
A1  - Nodzenski, Michael
A1  - Schnurr, Theresia M.
A1  - Zafarmand, Mohammad Hadi
A1  - Bradfield, Jonathan P.
A1  - Grarup, Niels
A1  - Kooijman, Marjolein N.
A1  - Li-Gao, Ruifang
A1  - Geller, Frank
A1  - Ahluwalia, Tarunveer Singh
A1  - Paternoster, Lavinia
A1  - Rueedi, Rico
A1  - Huikari, Ville
A1  - Hottenga, Jouke-Jan
A1  - Lyytikäinen, Leo-Pekka
A1  - Cavadino, Alana
A1  - Metrustry, Sarah
A1  - Cousminer, Diana L.
A1  - Wu, Ying
A1  - Thiering, Elisabeth Paula
A1  - Wang, Carol A.
A1  - Have, Christian Theil
A1  - Vilor-Tejedor, Natalia
A1  - Joshi, Peter K.
A1  - Painter, Jodie N.
A1  - Ntalla, Ioanna
A1  - Myhre, Ronny
A1  - Pitkänen, Niina
A1  - van Leeuwen, Elisabeth M.
A1  - Joro, Raimo
A1  - Lagou, Vasiliki
A1  - Richmond, Rebecca C.
A1  - Espinosa, Ana
A1  - Barton, Sheila J.
A1  - Inskip, Hazel M.
A1  - Holloway, John W.
A1  - Santa-Marina, Loreto
A1  - Estivill, Xavier
A1  - Ang, Wei
A1  - Marsh, Julie A.
A1  - Reichetzeder, Christoph
A1  - Marullo, Letizia
A1  - Hocher, Berthold
A1  - Lunetta, Kathryn L.
A1  - Murabito, Joanne M.
A1  - Relton, Caroline L.
A1  - Kogevinas, Manolis
A1  - Chatzi, Leda
A1  - Allard, Catherine
A1  - Bouchard, Luigi
A1  - Hivert, Marie-France
A1  - Zhang, Ge
A1  - Muglia, Louis J.
A1  - Heikkinen, Jani
A1  - Morgen, Camilla S.
A1  - van Kampen, Antoine H. C.
A1  - van Schaik, Barbera D. C.
A1  - Mentch, Frank D.
A1  - Langenberg, Claudia
A1  - Scott, Robert A.
A1  - Zhao, Jing Hua
A1  - Hemani, Gibran
A1  - Ring, Susan M.
A1  - Bennett, Amanda J.
A1  - Gaulton, Kyle J.
A1  - Fernandez-Tajes, Juan
A1  - van Zuydam, Natalie R.
A1  - Medina-Gomez, Carolina
A1  - de Haan, Hugoline G.
A1  - Rosendaal, Frits R.
A1  - Kutalik, Zoltán
A1  - Marques-Vidal, Pedro
A1  - Das, Shikta
A1  - Willemsen, Gonneke
A1  - Mbarek, Hamdi
A1  - Müller-Nurasyid, Martina
A1  - Standl, Marie
A1  - Appel, Emil V. R.
A1  - Fonvig, Cilius Esmann
A1  - Trier, Caecilie
A1  - van Beijsterveldt, Catharina E. M.
A1  - Murcia, Mario
A1  - Bustamante, Mariona
A1  - Bonàs-Guarch, Sílvia
A1  - Hougaard, David M.
A1  - Mercader, Josep M.
A1  - Linneberg, Allan
A1  - Schraut, Katharina E.
A1  - Lind, Penelope A.
A1  - Medland, Sarah Elizabeth
A1  - Shields, Beverley M.
A1  - Knight, Bridget A.
A1  - Chai, Jin-Fang
A1  - Panoutsopoulou, Kalliope
A1  - Bartels, Meike
A1  - Sánchez, Friman
A1  - Stokholm, Jakob
A1  - Torrents, David
A1  - Vinding, Rebecca K.
A1  - Willems, Sara M.
A1  - Atalay, Mustafa
A1  - Chawes, Bo L.
A1  - Kovacs, Peter
A1  - Prokopenko, Inga
A1  - Tuke, Marcus A.
A1  - Yaghootkar, Hanieh
A1  - Ruth, Katherine S.
A1  - Jones, Samuel E.
A1  - Loh, Po-Ru
A1  - Murray, Anna
A1  - Weedon, Michael N.
A1  - Tönjes, Anke
A1  - Stumvoll, Michael
A1  - Michaelsen, Kim Fleischer
A1  - Eloranta, Aino-Maija
A1  - Lakka, Timo A.
A1  - van Duijn, Cornelia M.
A1  - Kiess, Wieland
A1  - Koerner, Antje
A1  - Niinikoski, Harri
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Jacobsson, Bo
A1  - Zeggini, Eleftheria
A1  - Dedoussis, George V.
A1  - Teo, Yik-Ying
A1  - Saw, Seang-Mei
A1  - Montgomery, Grant W.
A1  - Campbell, Harry
A1  - Wilson, James F.
A1  - Vrijkotte, Tanja G. M.
A1  - Vrijheid, Martine
A1  - de Geus, Eco J. C. N.
A1  - Hayes, M. Geoffrey
A1  - Kadarmideen, Haja N.
A1  - Holm, Jens-Christian
A1  - Beilin, Lawrence J.
A1  - Pennell, Craig E.
A1  - Heinrich, Joachim
A1  - Adair, Linda S.
A1  - Borja, Judith B.
A1  - Mohlke, Karen L.
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth E.
A1  - Hattersley, Andrew T.
A1  - Spector, Tim D.
A1  - Kaehoenen, Mika
A1  - Viikari, Jorma S.
A1  - Lehtimaeki, Terho
A1  - Boomsma, Dorret I.
A1  - Sebert, Sylvain
A1  - Vollenweider, Peter
A1  - Sorensen, Thorkild I. A.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Murray, Jeffrey C.
A1  - Melbye, Mads
A1  - Nohr, Ellen A.
A1  - Mook-Kanamori, Dennis O.
A1  - Rivadeneira, Fernando
A1  - Hofman, Albert
A1  - Felix, Janine F.
A1  - Jaddoe, Vincent W. V.
A1  - Hansen, Torben
A1  - Pisinger, Charlotta
A1  - Vaag, Allan A.
A1  - Pedersen, Oluf
A1  - Uitterlinden, Andre G.
A1  - Jarvelin, Marjo-Riitta
A1  - Power, Christine
A1  - Hypponen, Elina
A1  - Scholtens, Denise M.
A1  - Lowe, William L.
A1  - Smith, George Davey
A1  - Timpson, Nicholas J.
A1  - Morris, Andrew P.
A1  - Wareham, Nicholas J.
A1  - Hakonarson, Hakon
A1  - Grant, Struan F. A.
A1  - Frayling, Timothy M.
A1  - Lawlor, Debbie A.
A1  - Njolstad, Pal R.
A1  - Johansson, Stefan
A1  - Ong, Ken K.
A1  - McCarthy, Mark I.
A1  - Perry, John R. B.
A1  - Evans, David M.
A1  - Freathy, Rachel M.
T1  - Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
JF  - Nature genetics
N2  - Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Y1  - 2019
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 5
SP  - 804
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - GEN
A1  - Anderson, Christopher J.
A1  - Bahnik, Stepan
A1  - Barnett-Cowan, Michael
A1  - Bosco, Frank A.
A1  - Chandler, Jesse
A1  - Chartier, Christopher R.
A1  - Cheung, Felix
A1  - Christopherson, Cody D.
A1  - Cordes, Andreas
A1  - Cremata, Edward J.
A1  - Della Penna, Nicolas
A1  - Estel, Vivien
A1  - Fedor, Anna
A1  - Fitneva, Stanka A.
A1  - Frank, Michael C.
A1  - Grange, James A.
A1  - Hartshorne, Joshua K.
A1  - Hasselman, Fred
A1  - Henninger, Felix
A1  - van der Hulst, Marije
A1  - Jonas, Kai J.
A1  - Lai, Calvin K.
A1  - Levitan, Carmel A.
A1  - Miller, Jeremy K.
A1  - Moore, Katherine S.
A1  - Meixner, Johannes M.
A1  - Munafo, Marcus R.
A1  - Neijenhuijs, Koen I.
A1  - Nilsonne, Gustav
A1  - Nosek, Brian A.
A1  - Plessow, Franziska
A1  - Prenoveau, Jason M.
A1  - Ricker, Ashley A.
A1  - Schmidt, Kathleen
A1  - Spies, Jeffrey R.
A1  - Stieger, Stefan
A1  - Strohminger, Nina
A1  - Sullivan, Gavin B.
A1  - van Aert, Robbie C. M.
A1  - van Assen, Marcel A. L. M.
A1  - Vanpaemel, Wolf
A1  - Vianello, Michelangelo
A1  - Voracek, Martin
A1  - Zuni, Kellylynn
T1  - Response to Comment on "Estimating the reproducibility of psychological science"
T2  - Science
N2  - Gilbert et al. conclude that evidence from the Open Science Collaboration’s Reproducibility Project: Psychology indicates high reproducibility, given the study methodology. Their very optimistic assessment is limited by statistical misconceptions and by causal inferences from selectively interpreted, correlational data. Using the Reproducibility Project: Psychology data, both optimistic and pessimistic conclusions about reproducibility are possible, and neither are yet warranted.
Y1  - 2016
U6  - https://doi.org/10.1126/science.aad9163
SN  - 0036-8075
SN  - 1095-9203
VL  - 351
SP  - 1162
EP  - 1165
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - JOUR
A1  - Schwarze, Martin
A1  - Schellhammer, Karl Sebastian
A1  - Ortstein, Katrin
A1  - Benduhn, Johannes
A1  - Gaul, Christopher
A1  - Hinderhofer, Alexander
A1  - Perdigón-Toro, Lorena
A1  - Scholz, Reinhard
A1  - Kublitski, Jonas
A1  - Roland, Steffen
A1  - Lau, Matthias
A1  - Poelking, Carl
A1  - Andrienko, Denis
A1  - Cuniberti, Gianaurelio
A1  - Schreiber, Frank
A1  - Neher, Dieter
A1  - Vandewal, Koen
A1  - Ortmann, Frank
A1  - Leo, Karl
T1  - Impact of molecular quadrupole moments on the energy levels at organic heterojunctions
JF  - Nature Communications
N2  - The functionality of organic semiconductor devices crucially depends on molecular energies, namely the ionisation energy and the electron affinity. Ionisation energy and electron affinity values of thin films are, however, sensitive to film morphology and composition, making their prediction challenging. In a combined experimental and simulation study on zinc-phthalocyanine and its fluorinated derivatives, we show that changes in ionisation energy as a function of molecular orientation in neat films or mixing ratio in blends are proportional to the molecular quadrupole component along the p-p-stacking direction. We apply these findings to organic solar cells and demonstrate how the electrostatic interactions can be tuned to optimise the energy of the charge-transfer state at the donor-acceptor interface and the dissociation barrier for free charge carrier generation. The confirmation of the correlation between interfacial energies and quadrupole moments for other materials indicates its relevance for small molecules and polymers.
Y1  - 2019
U6  - https://doi.org/10.1038/s41467-019-10435-2
SN  - 2041-1723
VL  - 10
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Buratti, Bonnie J.
A1  - Thomas, P. C.
A1  - Roussos, Elias
A1  - Howett, Carly
A1  - Seiss, Martin
A1  - Hendrix, A. R.
A1  - Helfenstein, Paul
A1  - Brown, R. H.
A1  - Clark, R. N.
A1  - Denk, Tilmann
A1  - Filacchione, Gianrico
A1  - Hoffmann, Holger
A1  - Jones, Geraint H.
A1  - Khawaja, N.
A1  - Kollmann, Peter
A1  - Krupp, Norbert
A1  - Lunine, Jonathan
A1  - Momary, T. W.
A1  - Paranicas, Christopher
A1  - Postberg, Frank
A1  - Sachse, Manuel
A1  - Spahn, Frank
A1  - Spencer, John
A1  - Srama, Ralf
A1  - Albin, T.
A1  - Baines, K. H.
A1  - Ciarniello, Mauro
A1  - Economou, Thanasis
A1  - Hsu, Hsiang-Wen
A1  - Kempf, Sascha
A1  - Krimigis, Stamatios M.
A1  - Mitchell, Donald
A1  - Moragas-Klostermeyer, Georg
A1  - Nicholson, Philip D.
A1  - Porco, C. C.
A1  - Rosenberg, Heike
A1  - Simolka, Jonas
A1  - Soderblom, Laurence A.
T1  - Close Cassini flybys of Saturn’s ring moons Pan, Daphnis, Atlas, Pandora, and Epimetheus
JF  - Science
N2  - Saturn’s main ring system is associated with a set of small moons that either are embedded within it or interact with the rings to alter their shape and composition. Five close flybys of the moons Pan, Daphnis, Atlas, Pandora, and Epimetheus were performed between December 2016 and April 2017 during the ring-grazing orbits of the Cassini mission. Data on the moons’ morphology, structure, particle environment, and composition were returned, along with images in the ultraviolet and thermal infrared. We find that the optical properties of the moons’ surfaces are determined by two competing processes: contamination by a red material formed in Saturn’s main ring system and accretion of bright icy particles or water vapor from volcanic plumes originating on the moon Enceladus.
Y1  - 2019
U6  - https://doi.org/10.1126/science.aat2349
SN  - 0036-8075
SN  - 1095-9203
VL  - 364
IS  - 6445
SP  - 1053
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - THES
A1  - Frank, Jonas
T1  - Decentralization in Ecuador : actors, institutions, and incentives
Y1  - 2007
SN  - 978-3-8329-2708-0
PB  - Nomos
CY  - Baden-Baden
ER  - 
TY  - JOUR
A1  - Connor, Daniel Oliver
A1  - Zantow, Jonas
A1  - Hust, Michael
A1  - Bier, Frank Fabian
A1  - von Nickisch-Rosenegk, Markus
T1  - Identification of Novel Immunogenic Proteins of Neisseria gonorrhoeae by Phage Display
JF  - PLoS one
N2  - Neisseria gonorrhoeae is one of the most prevalent sexually transmitted diseases worldwide with more than 100 million new infections per year. A lack of intense research over the last decades and increasing resistances to the recommended antibiotics call for a better understanding of gonococcal infection, fast diagnostics and therapeutic measures against N. gonorrhoeae. Therefore, the aim of this work was to identify novel immunogenic proteins as a first step to advance those unresolved problems. For the identification of immunogenic proteins, pHORF oligopeptide phage display libraries of the entire N. gonorrhoeae genome were constructed. Several immunogenic oligopeptides were identified using polyclonal rabbit antibodies against N. gonorrhoeae. Corresponding full-length proteins of the identified oligopeptides were expressed and their immunogenic character was verified by ELISA. The immunogenic character of six proteins was identified for the first time. Additional 13 proteins were verified as immunogenic proteins in N. gonorrhoeae.
Y1  - 2016
U6  - https://doi.org/10.1371/journal.pone.0148986
SN  - 1932-6203
VL  - 11
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - GEN
A1  - Connor, Daniel Oliver
A1  - Zantow, Jonas
A1  - Hust, Michael
A1  - Bier, Frank Fabian
A1  - von Nickisch-Rosenegk, Markus
T1  - Identification of novel immunogenic proteins of Neisseria gonorrhoeae by phage display
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Neisseria gonorrhoeae is one of the most prevalent sexually transmitted diseases worldwide with more than 100 million new infections per year. A lack of intense research over the last decades and increasing resistances to the recommended antibiotics call for a better understanding of gonococcal infection, fast diagnostics and therapeutic measures against N. gonorrhoeae. Therefore, the aim of this work was to identify novel immunogenic proteins as a first step to advance those unresolved problems. For the identification of immunogenic proteins, pHORF oligopeptide phage display libraries of the entire N. gonorrhoeae genome were constructed. Several immunogenic oligopeptides were identified using polyclonal rabbit antibodies against N. gonorrhoeae. Corresponding full-length proteins of the identified oligopeptides were expressed and their immunogenic character was verified by ELISA. The immunogenic character of six proteins was identified for the first time. Additional 13 proteins were verified as immunogenic proteins in N. gonorrhoeae.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 541 
KW  - proteomic analysis
KW  - vaccine antigens
KW  - gene-expression
KW  - Mycobacterium tuberculosis
KW  - antimicrobial resistance
KW  - recombinant antibodies
KW  - Salmonella Thyphimurium
KW  - untreatable Gonorrhea
KW  - multidrug-resistant
KW  - Escherichia coli
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-411077
SN  - 1866-8372
IS  - 541
ER  - 
TY  - JOUR
A1  - Beye, Martin
A1  - Öberg, Henrik
A1  - Xin, Hongliang
A1  - Dakovski, Georgi L.
A1  - Föhlisch, Alexander
A1  - Gladh, Jorgen
A1  - Hantschmann, Markus
A1  - Hieke, Florian
A1  - Kaya, Sarp
A1  - Kühn, Danilo
A1  - LaRue, Jerry
A1  - Mercurio, Giuseppe
A1  - Minitti, Michael P.
A1  - Mitra, Ankush
A1  - Moeller, Stefan P.
A1  - Ng, May Ling
A1  - Nilsson, Anders
A1  - Nordlund, Dennis
A1  - Norskov, Jens
A1  - Öström, Henrik
A1  - Ogasawara, Hirohito
A1  - Persson, Mats
A1  - Schlotter, William F.
A1  - Sellberg, Jonas A.
A1  - Wolf, Martin
A1  - Abild-Pedersen, Frank
A1  - Pettersson, Lars G. M.
A1  - Wurth, Wilfried
T1  - Chemical Bond Activation Observed with an X-ray Laser
JF  - The journal of physical chemistry letters
N2  - The concept of bonding and antibonding orbitals is fundamental in chemistry. The population of those orbitals and the energetic difference between the two reflect the strength of the bonding interaction. Weakening the bond is expected to reduce this energetic splitting, but the transient character of bond-activation has so far prohibited direct experimental access. Here we apply time-resolved soft X-ray spectroscopy at a free electron laser to directly observe the decreased bonding antibonding splitting following bond-activation using an ultrashort optical laser pulse.
Y1  - 2016
U6  - https://doi.org/10.1021/acs.jpclett.6b01543
SN  - 1948-7185
VL  - 7
SP  - 3647
EP  - 3651
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Xin, Hong
A1  - LaRue, Jerry
A1  - Oberg, Henrik
A1  - Beye, Martin
A1  - Turner, J. J.
A1  - Gladh, Jörgen
A1  - Ng, May L.
A1  - Sellberg, Jonas A.
A1  - Kaya, Sarp
A1  - Mercurio, G.
A1  - Hieke, F.
A1  - Nordlund, Dennis
A1  - Schlotter, William F.
A1  - Dakovski, Georgi L.
A1  - Minitti, Michael P.
A1  - Föhlisch, Alexander
A1  - Wolf, Martin
A1  - Wurth, Wilfried
A1  - Ogasawara, Hirohito
A1  - Norskov, Jens K.
A1  - Ostrom, Henrik
A1  - Pettersson, Lars G. M.
A1  - Nilsson, Anders
A1  - Abild-Pedersen, Frank
T1  - Strong Influence of Coadsorbate Interaction on CO Desorption Dynamics on Ru(0001) Probed by Ultrafast X-Ray Spectroscopy and Ab Initio Simulations
JF  - Physical review letters
N2  - We show that coadsorbed oxygen atoms have a dramatic influence on the CO desorption dynamics from Ru(0001). In contrast to the precursor-mediated desorption mechanism on Ru(0001), the presence of surface oxygen modifies the electronic structure of Ru atoms such that CO desorption occurs predominantly via the direct pathway. This phenomenon is directly observed in an ultrafast pump-probe experiment using a soft x-ray free-electron laser to monitor the dynamic evolution of the valence electronic structure of the surface species. This is supported with the potential of mean force along the CO desorption path obtained from density-functional theory calculations. Charge density distribution and frozen-orbital analysis suggest that the oxygen-induced reduction of the Pauli repulsion, and consequent increase of the dative interaction between the CO 5 sigma and the charged Ru atom, is the electronic origin of the distinct desorption dynamics. Ab initio molecular dynamics simulations of CO desorption from Ru(0001) and oxygen-coadsorbed Ru(0001) provide further insights into the surface bond-breaking process.
Y1  - 2015
U6  - https://doi.org/10.1103/PhysRevLett.114.156101
SN  - 0031-9007
SN  - 1079-7114
VL  - 114
IS  - 15
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - BOOK
A1  - Alnemr, Rehab
A1  - Polyvyanyy, Artem
A1  - AbuJarour, Mohammed
A1  - Appeltauer, Malte
A1  - Hildebrandt, Dieter
A1  - Thomas, Ivonne
A1  - Overdick, Hagen
A1  - Schöbel, Michael
A1  - Uflacker, Matthias
A1  - Kluth, Stephan
A1  - Menzel, Michael
A1  - Schmidt, Alexander
A1  - Hagedorn, Benjamin
A1  - Pascalau, Emilian
A1  - Perscheid, Michael
A1  - Vogel, Thomas
A1  - Hentschel, Uwe
A1  - Feinbube, Frank
A1  - Kowark, Thomas
A1  - Trümper, Jonas
A1  - Vogel, Tobias
A1  - Becker, Basil
ED  - Meinel, Christoph
ED  - Plattner, Hasso
ED  - Döllner, Jürgen Roland Friedrich
ED  - Weske, Mathias
ED  - Polze, Andreas
ED  - Hirschfeld, Robert
ED  - Naumann, Felix
ED  - Giese, Holger
T1  - Proceedings of the 4th Ph.D. Retreat of the HPI Research School on Service-oriented Systems Engineering
T3  - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 31 
KW  - Hasso-Plattner-Institut
KW  - Forschungskolleg
KW  - Klausurtagung
KW  - Service-oriented Systems Engineering
KW  - Hasso Plattner Institute
KW  - Research School
KW  - Ph.D. Retreat
KW  - Service-oriented Systems Engineering
Y1  - 2010
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-40838
SN  - 978-3-86956-036-6
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Inal, Sahika
A1  - Kölsch, Jonas D.
A1  - Sellrie, Frank
A1  - Schenk, Jörg A.
A1  - Wischerhoff, Erik
A1  - Laschewsky, André
A1  - Neher, Dieter
T1  - A water soluble fluorescent polymer as a dual colour sensor for temperature and a specific protein
JF  - Journal of materials chemistry : B, Materials for biology and medicine
N2  - We present two thermoresponsive water soluble copolymers prepared via free radical statistical copolymerization of N-isopropylacrylamide (NIPAm) and of oligo(ethylene glycol) methacrylates (OEGMAs), respectively, with a solvatochromic 7-(diethylamino)-3-carboxy-coumarin (DEAC)-functionalized monomer. In aqueous solutions, the NIPAm-based copolymer exhibits characteristic changes in its fluorescence profile in response to a change in solution temperature as well as to the presence of a specific protein, namely an anti-DEAC antibody. This polymer emits only weakly at low temperatures, but exhibits a marked fluorescence enhancement accompanied by a change in its emission colour when heated above its cloud point. Such drastic changes in the fluorescence and absorbance spectra are observed also upon injection of the anti-DEAC antibody, attributed to the specific binding of the antibody to DEAC moieties. Importantly, protein binding occurs exclusively when the polymer is in the well hydrated state below the cloud point, enabling a temperature control on the molecular recognition event. On the other hand, heating of the polymer-antibody complexes releases a fraction of the bound antibody. In the presence of the DEAC-functionalized monomer in this mixture, the released antibody competitively binds to the monomer and the antibody-free chains of the polymer undergo a more effective collapse and inter-aggregation. In contrast, the emission properties of the OEGMA-based analogous copolymer are rather insensitive to the thermally induced phase transition or to antibody binding. These opposite behaviours underline the need for a carefully tailored molecular design of responsive polymers aimed at specific applications, such as biosensing.
Y1  - 2013
U6  - https://doi.org/10.1039/c3tb21245a
SN  - 2050-750X
SN  - 2050-7518
VL  - 1
IS  - 46
SP  - 6373
EP  - 6381
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Inal, Sahika
A1  - Kölsch, Jonas D.
A1  - Selrie, Frank
A1  - Schenk, Jörg A.
A1  - Wischerhoff, Erik
A1  - Laschewsky, André
A1  - Neher, Dieter
T1  - A water soluble fluorescent polymer as a dual colour sensor for temperature and a specific protein
N2  - We present two thermoresponsive water soluble copolymers prepared via free radical statistical copolymerization of N-isopropylacrylamide (NIPAm) and of oligo(ethylene glycol) methacrylates (OEGMAs), respectively, with a solvatochromic 7-(diethylamino)-3-carboxy-coumarin (DEAC)-functionalized monomer. In aqueous solutions, the NIPAm-based copolymer exhibits characteristic changes in its fluorescence profile in response to a change in solution temperature as well as to the presence of a specific protein, namely an anti-DEAC antibody. This polymer emits only weakly at low temperatures, but exhibits a marked fluorescence enhancement accompanied by a change in its emission colour when heated above its cloud point. Such drastic changes in the fluorescence and absorbance spectra are observed also upon injection of the anti-DEAC antibody, attributed to the specific binding of the antibody to DEAC moieties. Importantly, protein binding occurs exclusively when the polymer is in the well hydrated state below the cloud point, enabling a temperature control on the molecular recognition event. On the other hand, heating of the polymer-antibody complexes releases a fraction of the bound antibody. In the presence of the DEAC-functionalized monomer in this mixture, the released antibody competitively binds to the monomer and the antibody-free chains of the polymer undergo a more effective collapse and inter-aggregation. In contrast, the emission properties of the OEGMA-based analogous copolymer are rather insensitive to the thermally induced phase transition or to antibody binding. These opposite behaviours underline the need for a carefully tailored molecular design of responsive polymers aimed at specific applications, such as biosensing.
Y1  - 2013
UR  - http://pubs.rsc.org/en/content/articlepdf/2013/tb/c3tb21245a
U6  - https://doi.org/10.1039/c3tb21245a
ER  - 
TY  - BOOK
A1  - Rana, Kaushik
A1  - Mohapatra, Durga Prasad
A1  - Sidorova, Julia
A1  - Lundberg, Lars
A1  - Sköld, Lars
A1  - Lopes Grim, Luís Fernando
A1  - Sampaio Gradvohl, André Leon
A1  - Cremerius, Jonas
A1  - Siegert, Simon
A1  - Weltzien, Anton von
A1  - Baldi, Annika
A1  - Klessascheck, Finn
A1  - Kalancha, Svitlana
A1  - Lichtenstein, Tom
A1  - Shaabani, Nuhad
A1  - Meinel, Christoph
A1  - Friedrich, Tobias
A1  - Lenzner, Pascal
A1  - Schumann, David
A1  - Wiese, Ingmar
A1  - Sarna, Nicole
A1  - Wiese, Lena
A1  - Tashkandi, Araek Sami
A1  - van der Walt, Estée
A1  - Eloff, Jan H. P.
A1  - Schmidt, Christopher
A1  - Hügle, Johannes
A1  - Horschig, Siegfried
A1  - Uflacker, Matthias
A1  - Najafi, Pejman
A1  - Sapegin, Andrey
A1  - Cheng, Feng
A1  - Stojanovic, Dragan
A1  - Stojnev Ilić, Aleksandra
A1  - Djordjevic, Igor
A1  - Stojanovic, Natalija
A1  - Predic, Bratislav
A1  - González-Jiménez, Mario
A1  - de Lara, Juan
A1  - Mischkewitz, Sven
A1  - Kainz, Bernhard
A1  - van Hoorn, André
A1  - Ferme, Vincenzo
A1  - Schulz, Henning
A1  - Knigge, Marlene
A1  - Hecht, Sonja
A1  - Prifti, Loina
A1  - Krcmar, Helmut
A1  - Fabian, Benjamin
A1  - Ermakova, Tatiana
A1  - Kelkel, Stefan
A1  - Baumann, Annika
A1  - Morgenstern, Laura
A1  - Plauth, Max
A1  - Eberhard, Felix
A1  - Wolff, Felix
A1  - Polze, Andreas
A1  - Cech, Tim
A1  - Danz, Noel
A1  - Noack, Nele Sina
A1  - Pirl, Lukas
A1  - Beilharz, Jossekin Jakob
A1  - De Oliveira, Roberto C. L.
A1  - Soares, Fábio Mendes
A1  - Juiz, Carlos
A1  - Bermejo, Belen
A1  - Mühle, Alexander
A1  - Grüner, Andreas
A1  - Saxena, Vageesh
A1  - Gayvoronskaya, Tatiana
A1  - Weyand, Christopher
A1  - Krause, Mirko
A1  - Frank, Markus
A1  - Bischoff, Sebastian
A1  - Behrens, Freya
A1  - Rückin, Julius
A1  - Ziegler, Adrian
A1  - Vogel, Thomas
A1  - Tran, Chinh
A1  - Moser, Irene
A1  - Grunske, Lars
A1  - Szárnyas, Gábor
A1  - Marton, József
A1  - Maginecz, János
A1  - Varró, Dániel
A1  - Antal, János Benjamin
ED  - Meinel, Christoph
ED  - Polze, Andreas
ED  - Beins, Karsten
ED  - Strotmann, Rolf
ED  - Seibold, Ulrich
ED  - Rödszus, Kurt
ED  - Müller, Jürgen
T1  - HPI Future SOC Lab – Proceedings 2018
N2  - The “HPI Future SOC Lab” is a cooperation of the Hasso Plattner Institute (HPI) and industry partners. Its mission is to enable and promote exchange and interaction between the research community and the industry partners.
  The HPI Future SOC Lab provides researchers with free of charge access to a complete infrastructure of state of the art hard and software. This infrastructure includes components, which might be too expensive for an ordinary research environment, such as servers with up to 64 cores and 2 TB main memory. The offerings address researchers particularly from but not limited to the areas of computer science and business information systems. Main areas of research include cloud computing, parallelization, and In-Memory technologies.
  This technical report presents results of research projects executed in 2018. Selected projects have presented their results on April 17th and November 14th 2017 at the Future SOC Lab Day events.
N2  - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie.
  Am Lab wird interessierten Wissenschaftler:innen eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen Systeme, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler:innen in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. 
  In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2018 vorgestellt.  Ausgewählte Projekte stellten ihre Ergebnisse am 17. April und 14. November 2018 im Rahmen des Future SOC Lab Tags vor.
T3  - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 151 
KW  - Future SOC Lab
KW  - research projects
KW  - multicore architectures
KW  - in-memory technology
KW  - cloud computing
KW  - machine learning
KW  - artifical intelligence
KW  - Future SOC Lab
KW  - Forschungsprojekte
KW  - Multicore Architekturen
KW  - In-Memory Technologie
KW  - Cloud Computing
KW  - maschinelles Lernen
KW  - künstliche Intelligenz
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-563712
SN  - 978-3-86956-547-7
SN  - 1613-5652
SN  - 2191-1665
IS  - 151
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - GEN
A1  - Inal, Sahika
A1  - Kölsch, Jonas D.
A1  - Sellrie, Frank
A1  - Schenk, Jörg A.
A1  - Wischerhoff, Erik
A1  - Laschewsky, André
A1  - Neher, Dieter
T1  - A water soluble fluorescent polymer as a dual colour sensor for temperature and a specific protein
N2  - We present two thermoresponsive water soluble copolymers prepared via free radical statistical copolymerization of N-isopropylacrylamide (NIPAm) and of oligo(ethylene glycol) methacrylates (OEGMAs), respectively, with a solvatochromic 7-(diethylamino)-3-carboxy-coumarin (DEAC)- functionalized monomer. In aqueous solutions, the NIPAm-based copolymer exhibits characteristic changes in its fluorescence profile in response to a change in solution temperature as well as to the presence of a specific protein, namely an anti-DEAC antibody. This polymer emits only weakly at low temperatures, but exhibits a marked fluorescence enhancement accompanied by a change in its emission colour when heated above its cloud point. Such drastic changes in the fluorescence and absorbance spectra are observed also upon injection of the anti-DEAC antibody, attributed to the specific binding of the antibody to DEAC moieties. Importantly, protein binding occurs exclusively when the polymer is in the well hydrated state below the cloud point, enabling a temperature control on the molecular recognition event. On the other hand, heating of the polymer–antibody complexes releases a fraction of the bound antibody. In the presence of the DEAC-functionalized monomer in this mixture, the released antibody competitively binds to the monomer and the antibody-free chains of the polymer undergo a more effective collapse and inter-aggregation. In contrast, the emission properties of the OEGMA-based analogous copolymer are rather insensitive to the thermally induced phase transition or to antibody binding. These opposite behaviours underline the need for a carefully tailored molecular design of responsive polymers aimed at specific applications, such as biosensing.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 249 
KW  - intramolecular charge-transfer
KW  - phase-transitions
KW  - responsive polymers
KW  - sensitivity
KW  - thermometer
KW  - dyes
KW  - modulation
KW  - assemblies
KW  - antibodies
KW  - binding
Y1  - 2013
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-95336
SP  - 6373
EP  - 6381
ER  - 
TY  - BOOK
A1  - Kuban, Robert
A1  - Rotta, Randolf
A1  - Nolte, Jörg
A1  - Chromik, Jonas
A1  - Beilharz, Jossekin Jakob
A1  - Pirl, Lukas
A1  - Friedrich, Tobias
A1  - Lenzner, Pascal
A1  - Weyand, Christopher
A1  - Juiz, Carlos
A1  - Bermejo, Belen
A1  - Sauer, Joao
A1  - Coelh, Leandro dos Santos
A1  - Najafi, Pejman
A1  - Pünter, Wenzel
A1  - Cheng, Feng
A1  - Meinel, Christoph
A1  - Sidorova, Julia
A1  - Lundberg, Lars
A1  - Vogel, Thomas
A1  - Tran, Chinh
A1  - Moser, Irene
A1  - Grunske, Lars
A1  - Elsaid, Mohamed Esameldin Mohamed
A1  - Abbas, Hazem M.
A1  - Rula, Anisa
A1  - Sejdiu, Gezim
A1  - Maurino, Andrea
A1  - Schmidt, Christopher
A1  - Hügle, Johannes
A1  - Uflacker, Matthias
A1  - Nozza, Debora
A1  - Messina, Enza
A1  - Hoorn, André van
A1  - Frank, Markus
A1  - Schulz, Henning
A1  - Alhosseini Almodarresi Yasin, Seyed Ali
A1  - Nowicki, Marek
A1  - Muite, Benson K.
A1  - Boysan, Mehmet Can
A1  - Bianchi, Federico
A1  - Cremaschi, Marco
A1  - Moussa, Rim
A1  - Abdel-Karim, Benjamin M.
A1  - Pfeuffer, Nicolas
A1  - Hinz, Oliver
A1  - Plauth, Max
A1  - Polze, Andreas
A1  - Huo, Da
A1  - Melo, Gerard de
A1  - Mendes Soares, Fábio
A1  - Oliveira, Roberto Célio Limão de
A1  - Benson, Lawrence
A1  - Paul, Fabian
A1  - Werling, Christian
A1  - Windheuser, Fabian
A1  - Stojanovic, Dragan
A1  - Djordjevic, Igor
A1  - Stojanovic, Natalija
A1  - Stojnev Ilic, Aleksandra
A1  - Weidmann, Vera
A1  - Lowitzki, Leon
A1  - Wagner, Markus
A1  - Ifa, Abdessatar Ben
A1  - Arlos, Patrik
A1  - Megia, Ana
A1  - Vendrell, Joan
A1  - Pfitzner, Bjarne
A1  - Redondo, Alberto
A1  - Ríos Insua, David
A1  - Albert, Justin Amadeus
A1  - Zhou, Lin
A1  - Arnrich, Bert
A1  - Szabó, Ildikó
A1  - Fodor, Szabina
A1  - Ternai, Katalin
A1  - Bhowmik, Rajarshi
A1  - Campero Durand, Gabriel
A1  - Shevchenko, Pavlo
A1  - Malysheva, Milena
A1  - Prymak, Ivan
A1  - Saake, Gunter
ED  - Meinel, Christoph
ED  - Polze, Andreas
ED  - Beins, Karsten
ED  - Strotmann, Rolf
ED  - Seibold, Ulrich
ED  - Rödszus, Kurt
ED  - Müller, Jürgen
T1  - HPI Future SOC Lab – Proceedings 2019
N2  - The “HPI Future SOC Lab” is a cooperation of the Hasso Plattner Institute (HPI) and industry partners. Its mission is to enable and promote exchange and interaction between the research community and the industry partners.
  The HPI Future SOC Lab provides researchers with free of charge access to a complete infrastructure of state of the art hard and software. This infrastructure includes components, which might be too expensive for an ordinary research environment, such as servers with up to 64 cores and 2 TB main memory. The offerings address researchers particularly from but not limited to the areas of computer science and business information systems. Main areas of research include cloud computing, parallelization, and In-Memory technologies.
  This technical report presents results of research projects executed in 2019. Selected projects have presented their results on April 9th and November 12th 2019 at the Future SOC Lab Day events.
N2  - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie.
  Am Lab wird interessierten Wissenschaftlern eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen teilweise noch nicht am Markt verfügbare Technologien, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. 
  In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2019 vorgestellt.  Ausgewählte Projekte stellten ihre Ergebnisse am 09. April und 12. November 2019 im Rahmen des Future SOC Lab Tags vor.
T3  - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 158 
KW  - Future SOC Lab
KW  - research projects
KW  - multicore architectures
KW  - in-memory technology
KW  - cloud computing
KW  - machine learning
KW  - artifical intelligence
KW  - Future SOC Lab
KW  - Forschungsprojekte
KW  - Multicore Architekturen
KW  - In-Memory Technologie
KW  - Cloud Computing
KW  - maschinelles Lernen
KW  - künstliche Intelligenz
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-597915
SN  - 978-3-86956-564-4
SN  - 1613-5652
SN  - 2191-1665
IS  - 158
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Seroussi, Helene
A1  - Nowicki, Sophie
A1  - Simon, Erika
A1  - Abe-Ouchi, Ayako
A1  - Albrecht, Torsten
A1  - Brondex, Julien
A1  - Cornford, Stephen
A1  - Dumas, Christophe
A1  - Gillet-Chaulet, Fabien
A1  - Goelzer, Heiko
A1  - Golledge, Nicholas R.
A1  - Gregory, Jonathan M.
A1  - Greve, Ralf
A1  - Hoffman, Matthew J.
A1  - Humbert, Angelika
A1  - Huybrechts, Philippe
A1  - Kleiner, Thomas
A1  - Larourl, Eric
A1  - Leguy, Gunter
A1  - Lipscomb, William H.
A1  - Lowry, Daniel
A1  - Mengel, Matthias
A1  - Morlighem, Mathieu
A1  - Pattyn, Frank
A1  - Payne, Anthony J.
A1  - Pollard, David
A1  - Price, Stephen F.
A1  - Quiquet, Aurelien
A1  - Reerink, Thomas J.
A1  - Reese, Ronja
A1  - Rodehacke, Christian B.
A1  - Schlegel, Nicole-Jeanne
A1  - Shepherd, Andrew
A1  - Sun, Sainan
A1  - Sutter, Johannes
A1  - Van Breedam, Jonas
A1  - van de Wal, Roderik S. W.
A1  - Winkelmann, Ricarda
A1  - Zhang, Tong
T1  - initMIP-Antarctica
BT  - an ice sheet model initialization experiment of ISMIP6
JF  - The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union
N2  - Ice sheet numerical modeling is an important tool to estimate the dynamic contribution of the Antarctic ice sheet to sea level rise over the coming centuries. The influence of initial conditions on ice sheet model simulations, however, is still unclear. To better understand this influence, an initial state intercomparison exercise (initMIP) has been developed to compare, evaluate, and improve initialization procedures and estimate their impact on century-scale simulations. initMlP is the first set of experiments of the Ice Sheet Model Intercomparison Project for CMIP6 (ISMIP6), which is the primary Coupled Model Intercomparison Project Phase 6 (CMIP6) activity focusing on the Greenland and Antarctic ice sheets. Following initMlP-Greenland, initMlP-Antarctica has been designed to explore uncertainties associated with model initialization and spin-up and to evaluate the impact of changes in external forcings. Starting from the state of the Antarctic ice sheet at the end of the initialization procedure, three forward experiments are each run for 100 years: a control run, a run with a surface mass balance anomaly, and a run with a basal melting anomaly beneath floating ice. This study presents the results of initMlP-Antarctica from 25 simulations performed by 16 international modeling groups. The submitted results use different initial conditions and initialization methods, as well as ice flow model parameters and reference external forcings. We find a good agreement among model responses to the surface mass balance anomaly but large variations in responses to the basal melting anomaly. These variations can be attributed to differences in the extent of ice shelves and their upstream tributaries, the numerical treatment of grounding line, and the initial ocean conditions applied, suggesting that ongoing efforts to better represent ice shelves in continental-scale models should continue.
Y1  - 2019
U6  - https://doi.org/10.5194/tc-13-1441-2019
SN  - 1994-0416
SN  - 1994-0424
VL  - 13
IS  - 5
SP  - 1441
EP  - 1471
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Seroussi, Helene
A1  - Nowicki, Sophie
A1  - Payne, Antony J.
A1  - Goelzer, Heiko
A1  - Lipscomb, William H.
A1  - Abe-Ouchi, Ayako
A1  - Agosta, Cecile
A1  - Albrecht, Torsten
A1  - Asay-Davis, Xylar
A1  - Barthel, Alice
A1  - Calov, Reinhard
A1  - Cullather, Richard
A1  - Dumas, Christophe
A1  - Galton-Fenzi, Benjamin K.
A1  - Gladstone, Rupert
A1  - Golledge, Nicholas R.
A1  - Gregory, Jonathan M.
A1  - Greve, Ralf
A1  - Hattermann, Tore
A1  - Hoffman, Matthew J.
A1  - Humbert, Angelika
A1  - Huybrechts, Philippe
A1  - Jourdain, Nicolas C.
A1  - Kleiner, Thomas
A1  - Larour, Eric
A1  - Leguy, Gunter R.
A1  - Lowry, Daniel P.
A1  - Little, Chistopher M.
A1  - Morlighem, Mathieu
A1  - Pattyn, Frank
A1  - Pelle, Tyler
A1  - Price, Stephen F.
A1  - Quiquet, Aurelien
A1  - Reese, Ronja
A1  - Schlegel, Nicole-Jeanne
A1  - Shepherd, Andrew
A1  - Simon, Erika
A1  - Smith, Robin S.
A1  - Straneo, Fiammetta
A1  - Sun, Sainan
A1  - Trusel, Luke D.
A1  - Van Breedam, Jonas
A1  - van de Wal, Roderik S. W.
A1  - Winkelmann, Ricarda
A1  - Zhao, Chen
A1  - Zhang, Tong
A1  - Zwinger, Thomas
T1  - ISMIP6 Antarctica
BT  - a multi-model ensemble of the Antarctic ice sheet evolution over the 21st century
JF  - The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union
N2  - Ice flow models of the Antarctic ice sheet are commonly used to simulate its future evolution in response to different climate scenarios and assess the mass loss that would contribute to future sea level rise. However, there is currently no consensus on estimates of the future mass balance of the ice sheet, primarily because of differences in the representation of physical processes, forcings employed and initial states of ice sheet models. This study presents results from ice flow model simulations from 13 international groups focusing on the evolution of the Antarctic ice sheet during the period 2015-2100 as part of the Ice Sheet Model Intercomparison for CMIP6 (ISMIP6). They are forced with outputs from a subset of models from the Coupled Model Intercomparison Project Phase 5 (CMIP5), representative of the spread in climate model results. Simulations of the Antarctic ice sheet contribution to sea level rise in response to increased warming during this period varies between 7:8 and 30.0 cm of sea level equivalent (SLE) under Representative Concentration Pathway (RCP) 8.5 scenario forcing. These numbers are relative to a control experiment with constant climate conditions and should therefore be added to the mass loss contribution under climate conditions similar to present-day conditions over the same period. The simulated evolution of the West Antarctic ice sheet varies widely among models, with an overall mass loss, up to 18.0 cm SLE, in response to changes in oceanic conditions. East Antarctica mass change varies between 6 :1 and 8.3 cm SLE in the simulations, with a significant increase in surface mass balance outweighing the increased ice discharge under most RCP 8.5 scenario forcings. The inclusion of ice shelf collapse, here assumed to be caused by large amounts of liquid water ponding at the surface of ice shelves, yields an additional simulated mass loss of 28mm compared to simulations without ice shelf collapse. The largest sources of uncertainty come from the climate forcing, the ocean-induced melt rates, the calibration of these melt rates based on oceanic conditions taken outside of ice shelf cavities and the ice sheet dynamic response to these oceanic changes. Results under RCP 2.6 scenario based on two CMIP5 climate models show an additional mass loss of 0 and 3 cm of SLE on average compared to simulations done under present-day conditions for the two CMIP5 forcings used and display limited mass gain in East Antarctica.
Y1  - 2020
U6  - https://doi.org/10.5194/tc-14-3033-2020
SN  - 1994-0416
SN  - 1994-0424
VL  - 14
IS  - 9
SP  - 3033
EP  - 3070
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Rockström, Johan
A1  - Kotzé, Louis
A1  - Milutinović, Svetlana
A1  - Biermann, Frank
A1  - Brovkin, Victor
A1  - Donges, Jonathan
A1  - Ebbesson, Jonas
A1  - French, Duncan
A1  - Gupta, Joyeeta
A1  - Kim, Rakhyun
A1  - Lenton, Timothy
A1  - Lenzi, Dominic
A1  - Nakicenovic, Nebojsa
A1  - Neumann, Barbara
A1  - Schuppert, Fabian
A1  - Winkelmann, Ricarda
A1  - Bosselmann, Klaus
A1  - Folke, Carl
A1  - Lucht, Wolfgang
A1  - Schlosberg, David
A1  - Richardson, Katherine
A1  - Steffen, Will
T1  - The planetary commons
BT  - a new paradigm for safeguarding earth-regulating systems in the Anthropocene
JF  - Proceedings of the National Academy of Sciences of the United States of America
N2  - The Anthropocene signifies the start of a no- analogue tra­jectory of the Earth system that is fundamentally different from the Holocene. This new trajectory is characterized by rising risks of triggering irreversible and unmanageable shifts in Earth system functioning. We urgently need a new global approach to safeguard critical Earth system regulating functions more effectively and comprehensively. The global commons framework is the closest example of an existing approach with the aim of governing biophysical systems  on  Earth  upon  which  the  world  collectively depends. Derived during stable Holocene conditions, the global commons framework must now evolve in the light of new Anthropocene dynamics. This requires a fundamental shift from a focus only on governing shared resources beyond national jurisdiction, to one that secures critical functions  of  the  Earth  system  irrespective  of  national boundaries. We propose a new framework—the planetary commons—which differs from the global commons frame­work by including not only globally shared geographic regions but also critical biophysical systems that regulate the resilience and state, and therefore livability, on Earth. The new planetary commons should articulate and create comprehensive  stewardship  obligations  through  Earth system governance aimed at restoring and strengthening planetary resilience and justice.
KW  - anthropocene
KW  - earth system governance
KW  - global commons
KW  - international law
KW  - planetary boundaries
Y1  - 2024
U6  - https://doi.org/10.1073/pnas.2301531121
SN  - 1091-6490
SN  - 1877-2014
VL  - 121
IS  - 5
PB  - National Academy of Sciences
CY  - Washington, DC
ER  -