TY  - GEN
A1  - Weymar, Mathias
A1  - Ventura-Bort, Carlos
A1  - Wirkner, Janine
A1  - Genheimer, Hannah
A1  - Wendt, Julia
A1  - Hamm, Alfons O.
T1  - Effects of Transcutaneous Vagus  Vagus Nerve Stimulation (TVNS) on 
 selective attentions and emotional episodic memory : findings from   ERP research
T2  - Psychophysiology : journal of the Society for Psychophysiological Research
N2  - Recent research indicates that non- invasive stimulation of the afferent auricular vagal nerve (tVNS) may modulate various cognitive and affec-tive functions, likely via activation of the locus coeruleus- norepinephrine (LC- NE) system. In a series of ERP studies we found that the attention- related P300 component is enhanced during continuous vagal stimula-tion, compared to sham, which is also related to increased salivary alpha amylase levels (a putative indirect marker for central NE activation). In another study, we investigated the effect of continuous tVNS on the late positive potential (LPP), an electrophysiological index for motivated atten-tion toward emotionally evocative cues, and the effects of tVNS on later recognition memory (1- week delay). Here, vagal stimulation prompted earlier LPP differences (300- 500 ms) between unpleasant and neutral scenes. During retrieval, vagal stimulation significantly improved memory performance for unpleasant, but not neutral pictures, compared to sham stimulation, which was also related to enhanced salivary alpha amylase levels. In line, unpleasant images encoded under tVNS compared to sham stimulation also produced enhanced ERP old/new differences (500- 800 ms) during retrieval indicating better recollection. Taken together, our studies suggest that tVNS facilitates attention, learning and episodic memory, likely via afferent projections to the arousal- modulated LC- NE system. We will, however, also show data that point to critical stimulation parameters (likely duration and frequency) that need to be considered when applying tVNS
Y1  - 2019
U6  - https://doi.org/10.1111/psyp.13501
SN  - 0048-5772
SN  - 1469-8986
VL  - 56
SP  - S12
EP  - S12
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Weymar, Mathias
A1  - Ventura-Bort, Carlos
A1  - Wirkner, Janine
A1  - Wendt, Julia
A1  - Hamm, Alfons
T1  - Effects of Transcutaneous Vagus Nerve Stimulation (TVNS) on unpleasant picture processing and long-term memory
T2  - Psychophysiology : journal of the Society for Psychophysiological Research
Y1  - 2018
SN  - 0048-5772
SN  - 1469-8986
VL  - 55
SP  - S18
EP  - S18
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Weymar, Mathias
A1  - Ventura-Bort, Carlos
A1  - Genheimer, Hannah
A1  - Wirkner, Janine
A1  - Wendt, Julia
A1  - Hamm, Alfons O.
T1  - THE P300 AND THE LC-NE SYSTEM: NEW INSIGHTS FROM TRANSCUTANEOUS VAGUS NERVE STIMULATION (TVNS)
T2  - Psychophysiology : journal of the Society for Psychophysiological Research
KW  - P300
KW  - norepinephrine
KW  - transcutaneous vagus nerve stimulation
Y1  - 2017
SN  - 0048-5772
SN  - 1469-8986
VL  - 54
SP  - S145
EP  - S145
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Wirkner, Janine
A1  - Low, Andreas
A1  - Struck, Anne-Marie
A1  - Hamm, Alfons O.
A1  - Weymar, Mathias
T1  - DOES AGE INFLUENCE BRAIN POTENTIALS DURING AFFECTIVE PICTURE PROCESSING IN MIDDLE-AGED WOMEN?
T2  - Psychophysiology : journal of the Society for Psychophysiological Research
Y1  - 2017
SN  - 0048-5772
SN  - 1469-8986
VL  - 54
SP  - S40
EP  - S40
PB  - Wiley
CY  - Hoboken
ER  -