TY - JOUR A1 - Yang, Jie A1 - Zhu, Xiaolei A1 - Wolf, Thomas J. A. A1 - Li, Zheng A1 - Nunes, João Pedro Figueira A1 - Coffee, Ryan A1 - Cryan, James P. A1 - Gühr, Markus A1 - Hegazy, Kareem A1 - Heinz, Tony F. A1 - Jobe, Keith A1 - Li, Renkai A1 - Shen, Xiaozhe A1 - Veccione, Theodore A1 - Weathersby, Stephen A1 - Wilkin, Kyle J. A1 - Yoneda, Charles A1 - Zheng, Qiang A1 - Martinez, Todd J. A1 - Centurion, Martin A1 - Wang, Xijie T1 - Imaging CF3I conical intersection and photodissociation dynamics with ultrafast electron diffraction JF - Science N2 - Conical intersections play a critical role in excited-state dynamics of polyatomic molecules because they govern the reaction pathways of many nonadiabatic processes. However, ultrafast probes have lacked sufficient spatial resolution to image wave-packet trajectories through these intersections directly. Here, we present the simultaneous experimental characterization of one-photon and two-photon excitation channels in isolated CF3I molecules using ultrafast gas-phase electron diffraction. In the two-photon channel, we have mapped out the real-space trajectories of a coherent nuclear wave packet, which bifurcates onto two potential energy surfaces when passing through a conical intersection. In the one-photon channel, we have resolved excitation of both the umbrella and the breathing vibrational modes in the CF3 fragment in multiple nuclear dimensions. These findings benchmark and validate ab initio nonadiabatic dynamics calculations. Y1 - 2018 U6 - https://doi.org/10.1126/science.aat0049 SN - 0036-8075 SN - 1095-9203 VL - 361 IS - 6397 SP - 64 EP - 67 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Tang, Alan T. A1 - Sullivan, Katie Rose A1 - Hong, Courtney C. A1 - Goddard, Lauren M. A1 - Mahadevan, Aparna A1 - Ren, Aileen A1 - Pardo, Heidy A1 - Peiper, Amy A1 - Griffin, Erin A1 - Tanes, Ceylan A1 - Mattei, Lisa M. A1 - Yang, Jisheng A1 - Li, Li A1 - Mericko-Ishizuka, Patricia A1 - Shen, Le A1 - Hobson, Nicholas A1 - Girard, Romuald A1 - Lightle, Rhonda A1 - Moore, Thomas A1 - Shenkar, Robert A1 - Polster, Sean P. A1 - Roedel, Claudia Jasmin A1 - Li, Ning A1 - Zhu, Qin A1 - Whitehead, Kevin J. A1 - Zheng, Xiangjian A1 - Akers, Amy A1 - Morrison, Leslie A1 - Kim, Helen A1 - Bittinger, Kyle A1 - Lengner, Christopher J. A1 - Schwaninger, Markus A1 - Velcich, Anna A1 - Augenlicht, Leonard A1 - Abdelilah-Seyfried, Salim A1 - Min, Wang A1 - Marchuk, Douglas A. A1 - Awad, Issam A. A1 - Kahn, Mark L. T1 - Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation JF - Science Translational Medicine N2 - Cerebral cavernous malformation (CCM) is a genetic, cerebrovascular disease. Familial CCM is caused by genetic mutations in KRIT1, CCM2, or PDCD10. Disease onset is earlier and more severe in individuals with PDCD10 mutations. Recent studies have shown that lesions arise from excess mitogen-activated protein kinase kinase kinase 3 (MEKK3) signaling downstream of Toll-like receptor 4 (TLR4) stimulation by lipopolysaccharide derived from the gut microbiome. These findings suggest a gut-brain CCM disease axis but fail to define it or explain the poor prognosis of patients with PDCD10 mutations. Here, we demonstrate that the gut barrier is a primary determinant of CCM disease course, independent of microbiome configuration, that explains the increased severity of CCM disease associated with PDCD10 deficiency. Chemical disruption of the gut barrier with dextran sulfate sodium augments CCM formation in a mouse model, as does genetic loss of Pdcd10, but not Krit1, in gut epithelial cells. Loss of gut epithelial Pdcd10 results in disruption of the colonic mucosal barrier. Accordingly, loss of Mucin-2 or exposure to dietary emulsifiers that reduce the mucus barrier increases CCM burden analogous to loss of Pdcd10 in the gut epithelium. Last, we show that treatment with dexamethasone potently inhibits CCM formation in mice because of the combined effect of action at both brain endothelial cells and gut epithelial cells. These studies define a gut-brain disease axis in an experimental model of CCM in which a single gene is required for two critical components: gut epithelial function and brain endothelial signaling. Y1 - 2019 U6 - https://doi.org/10.1126/scitranslmed.aaw3521 SN - 1946-6234 SN - 1946-6242 VL - 11 IS - 520 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Qu, J. Q. A1 - Zhang, J. Y. A1 - Grimsdale, A. C. A1 - Mullen, K. A1 - Jaiser, Frank A1 - Yang, X. H. A1 - Neher, Dieter T1 - Dendronized perylene diimide emitters : Synthesis, luminescence, and electron and energy transfer studies N2 - Aggregation of chromophores in the solid state commonly causes undesirable red shifts in the emission spectra and/or emission quenching. To overcome this problem, we have prepared soluble perylenetetracarboxidiimide dyes in which the chromophores are effectively shielded by polyphenylene dendrimers attached in the bay positions. Models show that attachment of the shielding units in the bay position should provide more efficient shielding than attaching them via the imide moieties. The dendrimers possess excellent film-forming properties due to alkyl substituents on their peripheries. The lack of a red shift in emission upon going from solution to the solid state indicates the dendrons suppress interaction of the emissive cores, leading to pure red-orange emission. Single-layer LEDs produce red-orange emission with relatively low efficiency especially for the higher generation dendrons, which is attributed to poor charge conduction. LEDs using blends of the dendrimers and the undendronized dye as a model compound in PVK have been investigated, and a model to extract relative charge injection rates through the dendritic scaffold from the spectral contributions in the EL spectra is developed Y1 - 2004 SN - 0024-9297 ER - TY - JOUR A1 - Huang, Wentao A1 - Jackson, Michael J. A1 - Dekkers, Mark J. A1 - Zhang, Yang A1 - Zhang, Bo A1 - Guo, Zhaojie A1 - Dupont-Nivet, Guillaume T1 - Challenges in isolating primary remanent magnetization from Tethyan carbonate rocks on the Tibetan Plateau: Insight from remagnetized Upper Triassic limestones in the eastern Qiangtang block JF - Earth & planetary science letters N2 - Carbonate rocks, widely used for paleomagnetically quantifying the drift history of the Gondwana derived continental blocks of the Tibetan Plateau and evolution of the Paleo/Meso/Neo-Tethys Oceans, are prone to pervasive remagnetization. Identifying remagnetization is difficult because it is commonly undetectable through the classic paleomagnetic field tests. Here we apply comprehensive paleomagnetic, rock magnetic, and petrographic studies to upper Triassic limestones in the eastern Qiangtang block. Our results reveal that detrital/biogenic magnetite, which may carry the primary natural remanent magnetization (NRM), is rarely preserved in these rocks. In contrast, authigenic magnetite and hematite pseudomorphs after pyrite, and monoclinic pyrrhotite record three episodes of remagnetization. The earliest remagnetization was induced by oxidation of early diagenetic pyrite to magnetite, probably related to the collision between the northeastern Tibetan Plateau and the Qiangtang block after closure of the Paleo-Tethys Ocean in the Late Triassic. The second remagnetization, residing in hematite and minor goethite, which is the further subsurface oxidation product of pyrite/magnetite, is possibly related to the development of the localized Cenozoic basins soon after India-Asia collision in the Paleocene. The youngest remagnetization is a combination of thermoviscous and chemical remanent magnetization carried by authigenic magnetite and pyrrhotite, respectively. Our analyses suggest that a high supply of organic carbon during carbonate deposition, prevailing sulfate reducing conditions during early diagenesis, and widespread orogenic fluid migration related to crustal shortening during later diagenesis, have altered the primary remanence of the shallow-water Tethyan carbonate rocks of the Tibetan Plateau. We emphasize that all paleomagnetic results from these rocks must be carefully examined for remagnetization before being used for paleogeographic reconstructions. Future paleomagnetic investigations of the carbonate rocks in orogenic belts should be accompanied by thorough rock magnetic and petrographic studies to determine the origin of the NRM. (C) 2019 Elsevier B.V. All rights reserved. KW - Triassic limestone KW - remagnetization KW - Tibetan Plateau Y1 - 2019 U6 - https://doi.org/10.1016/j.epsl.2019.06.035 SN - 0012-821X SN - 1385-013X VL - 523 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Müller, Katharina A1 - Foerstendorf, Harald A1 - Steudtner, Robin A1 - Tsushima, Satoru A1 - Kumke, Michael Uwe A1 - Lefèvre, Grégory A1 - Rothe, Jörg A1 - Mason, Harris A1 - Szabó, Zoltán A1 - Yang, Ping A1 - Adam, Christian K. R. A1 - André, Rémi A1 - Brennenstuhl, Katlen A1 - Chiorescu, Ion A1 - Cho, Herman M. A1 - Creff, Gaëlle A1 - Coppin, Frédéric A1 - Dardenne, Kathy A1 - Den Auwer, Christophe A1 - Drobot, Björn A1 - Eidner, Sascha A1 - Hess, Nancy J. A1 - Kaden, Peter A1 - Kremleva, Alena A1 - Kretzschmar, Jerome A1 - Krüger, Sven A1 - Platts, James A. A1 - Panak, Petra A1 - Polly, Robert A1 - Powell, Brian A. A1 - Rabung, Thomas A1 - Redon, Roland A1 - Reiller, Pascal E. A1 - Rösch, Notker A1 - Rossberg, André A1 - Scheinost, Andreas C. A1 - Schimmelpfennig, Bernd A1 - Schreckenbach, Georg A1 - Skerencak-Frech, Andrej A1 - Sladkov, Vladimir A1 - Solari, Pier Lorenzo A1 - Wang, Zheming A1 - Washton, Nancy M. A1 - Zhang, Xiaobin T1 - Interdisciplinary Round-Robin Test on molecular spectroscopy of the U(VI) Acetate System JF - ACS omega / American Chemical Society N2 - A comprehensive molecular analysis of a simple aqueous complexing system. U(VI) acetate. selected to be independently investigated by various spectroscopic (vibrational, luminescence, X-ray absorption, and nuclear magnetic resonance spectroscopy) and quantum chemical methods was achieved by an international round-robin test (RRT). Twenty laboratories from six different countries with a focus on actinide or geochemical research participated and contributed to this scientific endeavor. The outcomes of this RRT were considered on two levels of complexity: first, within each technical discipline, conformities as well as discrepancies of the results and their sources were evaluated. The raw data from the different experimental approaches were found to be generally consistent. In particular, for complex setups such as accelerator-based X-ray absorption spectroscopy, the agreement between the raw data was high. By contrast, luminescence spectroscopic data turned out to be strongly related to the chosen acquisition parameters. Second, the potentials and limitations of coupling various spectroscopic and theoretical approaches for the comprehensive study of actinide molecular complexes were assessed. Previous spectroscopic data from the literature were revised and the benchmark data on the U(VI) acetate system provided an unambiguous molecular interpretation based on the correlation of spectroscopic and theoretical results. The multimethodologic approach and the conclusions drawn address not only important aspects of actinide spectroscopy but particularly general aspects of modern molecular analytical chemistry. Y1 - 2019 U6 - https://doi.org/10.1021/acsomega.9b00164 SN - 2470-1343 VL - 4 IS - 5 SP - 8167 EP - 8177 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Xu, Jingsan A1 - Cao, Shaowen A1 - Brenner, Thomas J. K. A1 - Yang, Xiaofei A1 - Yu, Jiaguo A1 - Antonietti, Markus A1 - Shalom, Menny T1 - Supramolecular Chemistry in Molten Sulfur: Preorganization Effects Leading to Marked Enhancement of Carbon Nitride Photoelectrochemistry JF - Advanced functional materials N2 - Here, a new method for enhancing the photoelectrochemical properties of carbon nitride thin films by in situ supramolecular-driven preorganization of phenyl-contained monomers in molten sulfur is reported. A detailed analysis of the chemical and photophysical properties suggests that the molten sulfur can texture the growth and induce more effective integration of phenyl groups into the carbon nitride electrodes, resulting in extended light absorption alongside with improved conductivity and better charge transfer. Furthermore, photophysical measurements indicate the formation of sub-bands in the optical bandgap which is beneficial for exciton splitting. Moreover, the new bands can mediate hole transfer to the electrolyte, thus improving the photooxidation activity. The utilization of high temperature solvent as the polymerization medium opens new opportunities for the significant improvement of carbon nitride films toward an efficient photoactive material for various applications. KW - carbon nitride thin film KW - charge transfer KW - molten sulfur KW - photoelectrochemistry Y1 - 2015 U6 - https://doi.org/10.1002/adfm.201502843 SN - 1616-301X SN - 1616-3028 VL - 25 IS - 39 SP - 6265 EP - 6271 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Koenig, H. J. A1 - Zhen, L. A1 - Helming, K. A1 - Uthes, S. A1 - Yang, L. A1 - Cao, Xianyong A1 - Wiggering, Hubert T1 - Assessing the impact of the sloping land conversion programme on rural sustainability in Guyuan, Western China JF - Land degradation & development N2 - The goal of China's sloping land conversion programme (SLCP) is to combat soil erosion and to reduce rural poverty. An ex-ante assessment of possible SLCP impacts was conducted with a focus on rural sustainability, taking the drought-prone region of Guyuan in Western China as an example. The Framework for Participatory Impact Assessment (FoPIA) was used to conduct two complementary impact assessments, one assessing SLCP impacts at regional level and a second one assessing alternative forest management options, to explore possible trade-offs among the economic, social and environmental dimensions of sustainability. Regional stakeholders assessed the SLCP to be capable of reducing soil erosion but felt it negatively affected rural employment, and a further continuation of the Programme was advocated. Assessment of three forest management scenarios by scientists showed that an orientation towards energy forests is potentially beneficial to all three sustainability dimensions. Ecological forests had disproportionate positive impacts on environmental functions and adverse impact on the other two sustainability dimensions. Economic forests were assessed to serve primarily the economic and social sustainability dimensions, while environmental impacts were still tolerable. The FoPIA results were evaluated against the available literature on the SLCP. Overall, the assessment results appeared to be reasonable, but the results of the regional stakeholders appeared to be too optimistic compared with the more critical assessment of the scientists. The SLCP seems to have the potential to tackle soil erosion but requires integrated forest management to minimize the risk of water stress while contributing to economic and social benefits in Guyuan. Copyright (C) 2012 John Wiley & Sons, Ltd. KW - land conversion KW - land use KW - afforestation KW - land use functions KW - Grain for Green Project KW - ex-ante impact assessment KW - sustainable development KW - stakeholder participation Y1 - 2014 U6 - https://doi.org/10.1002/ldr.2164 SN - 1085-3278 SN - 1099-145X VL - 25 IS - 4 SP - 385 EP - 396 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Li, Chenhong A1 - Corrigan, Shannon A1 - Yang, Lei A1 - Straube, Nicolas A1 - Harris, Mark A1 - Hofreiter, Michael A1 - White, William T. A1 - Naylor, Gavin J. P. T1 - DNA capture reveals transoceanic gene flow in endangered river sharks JF - Proceedings of the National Academy of Sciences of the United States of America N2 - For over a hundred years, the "river sharks" of the genus Glyphis were only known from the type specimens of species that had been collected in the 19th century. They were widely considered extinct until populations of Glyphis-like sharks were rediscovered in remote regions of Borneo and Northern Australia at the end of the 20th century. However, the genetic affinities between the newly discovered Glyphis-like populations and the poorly preserved, original museum-type specimens have never been established. Here, we present the first (to our knowledge) fully resolved, complete phylogeny of Glyphis that includes both archival-type specimens and modern material. We used a sensitive DNA hybridization capture method to obtain complete mitochondrial genomes from all of our samples and show that three of the five described river shark species are probably conspecific and widely distributed in Southeast Asia. Furthermore we show that there has been recent gene flow between locations that are separated by large oceanic expanses. Our data strongly suggest marine dispersal in these species, overturning the widely held notion that river sharks are restricted to freshwater. It seems that species in the genus Glyphis are euryhaline with an ecology similar to the bull shark, in which adult individuals live in the ocean while the young grow up in river habitats with reduced predation pressure. Finally, we discovered a previously unidentified species within the genus Glyphis that is deeply divergent from all other lineages, underscoring the current lack of knowledge about the biodiversity and ecology of these mysterious sharks. KW - freshwater sharks KW - DNA KW - museum specimens Y1 - 2015 U6 - https://doi.org/10.1073/pnas.1508735112 SN - 0027-8424 VL - 112 IS - 43 SP - 13302 EP - 13307 PB - National Acad. of Sciences CY - Washington ER - TY - JOUR A1 - Banks, Jo Ann A1 - Nishiyama, Tomoaki A1 - Hasebe, Mitsuyasu A1 - Bowman, John L. A1 - Gribskov, Michael A1 - dePamphilis, Claude A1 - Albert, Victor A. A1 - Aono, Naoki A1 - Aoyama, Tsuyoshi A1 - Ambrose, Barbara A. A1 - Ashton, Neil W. A1 - Axtell, Michael J. A1 - Barker, Elizabeth A1 - Barker, Michael S. A1 - Bennetzen, Jeffrey L. A1 - Bonawitz, Nicholas D. A1 - Chapple, Clint A1 - Cheng, Chaoyang A1 - Correa, Luiz Gustavo Guedes A1 - Dacre, Michael A1 - DeBarry, Jeremy A1 - Dreyer, Ingo A1 - Elias, Marek A1 - Engstrom, Eric M. A1 - Estelle, Mark A1 - Feng, Liang A1 - Finet, Cedric A1 - Floyd, Sandra K. A1 - Frommer, Wolf B. A1 - Fujita, Tomomichi A1 - Gramzow, Lydia A1 - Gutensohn, Michael A1 - Harholt, Jesper A1 - Hattori, Mitsuru A1 - Heyl, Alexander A1 - Hirai, Tadayoshi A1 - Hiwatashi, Yuji A1 - Ishikawa, Masaki A1 - Iwata, Mineko A1 - Karol, Kenneth G. A1 - Koehler, Barbara A1 - Kolukisaoglu, Uener A1 - Kubo, Minoru A1 - Kurata, Tetsuya A1 - Lalonde, Sylvie A1 - Li, Kejie A1 - Li, Ying A1 - Litt, Amy A1 - Lyons, Eric A1 - Manning, Gerard A1 - Maruyama, Takeshi A1 - Michael, Todd P. A1 - Mikami, Koji A1 - Miyazaki, Saori A1 - Morinaga, Shin-ichi A1 - Murata, Takashi A1 - Müller-Röber, Bernd A1 - Nelson, David R. A1 - Obara, Mari A1 - Oguri, Yasuko A1 - Olmstead, Richard G. A1 - Onodera, Naoko A1 - Petersen, Bent Larsen A1 - Pils, Birgit A1 - Prigge, Michael A1 - Rensing, Stefan A. A1 - Mauricio Riano-Pachon, Diego A1 - Roberts, Alison W. A1 - Sato, Yoshikatsu A1 - Scheller, Henrik Vibe A1 - Schulz, Burkhard A1 - Schulz, Christian A1 - Shakirov, Eugene V. A1 - Shibagaki, Nakako A1 - Shinohara, Naoki A1 - Shippen, Dorothy E. A1 - Sorensen, Iben A1 - Sotooka, Ryo A1 - Sugimoto, Nagisa A1 - Sugita, Mamoru A1 - Sumikawa, Naomi A1 - Tanurdzic, Milos A1 - Theissen, Guenter A1 - Ulvskov, Peter A1 - Wakazuki, Sachiko A1 - Weng, Jing-Ke A1 - Willats, William W. G. T. A1 - Wipf, Daniel A1 - Wolf, Paul G. A1 - Yang, Lixing A1 - Zimmer, Andreas D. A1 - Zhu, Qihui A1 - Mitros, Therese A1 - Hellsten, Uffe A1 - Loque, Dominique A1 - Otillar, Robert A1 - Salamov, Asaf A1 - Schmutz, Jeremy A1 - Shapiro, Harris A1 - Lindquist, Erika A1 - Lucas, Susan A1 - Rokhsar, Daniel A1 - Grigoriev, Igor V. T1 - The selaginella genome identifies genetic changes associated with the evolution of vascular plants JF - Science N2 - Vascular plants appeared similar to 410 million years ago, then diverged into several lineages of which only two survive: the euphyllophytes (ferns and seed plants) and the lycophytes. We report here the genome sequence of the lycophyte Selaginella moellendorffii (Selaginella), the first nonseed vascular plant genome reported. By comparing gene content in evolutionarily diverse taxa, we found that the transition from a gametophyte- to a sporophyte-dominated life cycle required far fewer new genes than the transition from a nonseed vascular to a flowering plant, whereas secondary metabolic genes expanded extensively and in parallel in the lycophyte and angiosperm lineages. Selaginella differs in posttranscriptional gene regulation, including small RNA regulation of repetitive elements, an absence of the trans-acting small interfering RNA pathway, and extensive RNA editing of organellar genes. Y1 - 2011 U6 - https://doi.org/10.1126/science.1203810 SN - 0036-8075 VL - 332 IS - 6032 SP - 960 EP - 963 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Chepkirui, Carolyne A1 - Ochieng, Purity J. A1 - Sarkar, Biswajyoti A1 - Hussain, Aabid A1 - Pal, Chiranjib A1 - Yang, Li Jun A1 - Coghi, Paolo A1 - Akala, Hoseah M. A1 - Derese, Solomon A1 - Ndakala, Albert A1 - Heydenreich, Matthias A1 - Wong, Vincent K. W. A1 - Erdelyi, Mate A1 - Yenesew, Abiy T1 - Antiplasmodial and antileishmanial flavonoids from Mundulea sericea JF - Fitoterapia N2 - Five known compounds (1-5) were isolated from the extract of Mundulea sericea leaves. Similar investigation of the roots of this plant afforded an additional three known compounds (6-8). The structures were elucidated using NMR spectroscopic and mass spectrometric analyses. The absolute configuration of 1 was established using ECD spectroscopy. In an antiplasmodial activity assay, compound 1 showed good activity with an IC50 of 2.0 mu M against chloroquine-resistant W2, and 6.6 mu M against the chloroquine-sensitive 3D7 strains of Plasmodium falciparum. Some of the compounds were also tested for antileishmanial activity. Dehydrolupinifolinol (2) and sericetin (5) were active against drug-sensitive Leishmania donovani (MHOM/IN/83/AG83) with IC50 values of 9.0 and 5.0 mu M, respectively. In a cytotoxicity assay, lupinifolin (3) showed significant activity on BEAS-2B (IC50 4.9 mu M) and HePG2 (IC50 10.8 mu M) human cell lines. All the other compounds showed low cytotoxicity (IC50 > 30 mu M) against human lung adenocarcinoma cells (A549), human liver cancer cells (HepG2), lung/bronchus cells (epithelial virus transformed) (BEAS-2B) and immortal human hepatocytes (LO2) KW - Mundulea sericea KW - leguminosae KW - flavanonol KW - flavonol KW - antiplasmodial KW - antileishmanial KW - cytotoxicity Y1 - 2020 U6 - https://doi.org/10.1016/j.fitote.2020.104796 SN - 0367-326X SN - 1873-6971 VL - 149 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Angele, Bernhard A1 - Slattery, Timothy J. A1 - Yang, Jinmian A1 - Kliegl, Reinhold A1 - Rayner, Keith T1 - Parafoveal processing in reading : manipulating n+1 and n+2 previews simultaneously N2 - The boundary paradigm (Rayner, 1975) with a novel preview manipulation was used to examine the extent of parafoveal processing of words to the right of fixation. Words n + 1 and n + 2 had either correct or incorrect previews prior to fixation (prior to crossing the boundary location). In addition, the manipulation utilized either a high or low frequency word in word n + 1 location on the assumption that it would be more likely that n + 2 preview effects could be obtained when word n + 1 was high frequency. The primary findings were that there was no evidence for a preview benefit for word n + 2 and no evidence for parafoveal-on-foveal effects when word n + 1 is at least four letters long. We discuss implications for models of eye-movement control in reading. Y1 - 2008 UR - http://www.informaworld.com/smpp/title~content=t713683696~db=all U6 - https://doi.org/10.1080/13506280802009704 SN - 1350-6285 ER - TY - JOUR A1 - Agne, Stefanie A1 - Naylor, Gavin J. P. A1 - Preick, Michaela A1 - Yang, Lei A1 - Thiel, Ralf A1 - Weigmann, Simon A1 - Paijmans, Johanna L. A. A1 - Barlow, Axel A1 - Hofreiter, Michael A1 - Straube, Nicolas T1 - Taxonomic identification of two poorly known lantern shark species based on mitochondrial DNA from wet-collection paratypes JF - Frontiers in Ecology and Evolution N2 - Etmopteridae (lantern sharks) is the most species-rich family of sharks, comprising more than 50 species. Many species are described from few individuals, and re-collection of specimens is often hindered by the remoteness of their sampling sites. For taxonomic studies, comparative morphological analysis of type specimens housed in natural history collections has been the main source of evidence. In contrast, DNA sequence information has rarely been used. Most lantern shark collection specimens, including the types, were formalin fixed before long-term storage in ethanol solutions. The DNA damage caused by both fixation and preservation of specimens has excluded these specimens from DNA sequence-based phylogenetic analyses so far. However, recent advances in the field of ancient DNA have allowed recovery of wet-collection specimen DNA sequence data. Here we analyse archival mitochondrial DNA sequences, obtained using ancient DNA approaches, of two wet-collection lantern shark paratype specimens, namely Etmopterus litvinovi and E. pycnolepis, for which the type series represent the only known individuals. Target capture of mitochondrial markers from single-stranded DNA libraries allows for phylogenetic placement of both species. Our results suggest synonymy of E. benchleyi with E. litvinovi but support the species status of E. pycnolepis. This revised taxonomy is helpful for future conservation and management efforts, as our results indicate a larger distribution range of E. litvinovi. This study further demonstrates the importance of wet-collection type specimens as genetic resource for taxonomic research. KW - type specimens KW - Etmopterus litvinovi KW - Etmopterus pycnolepis KW - deep-sea KW - sharks KW - archival DNA Y1 - 2022 U6 - https://doi.org/10.3389/fevo.2022.910009 SN - 2296-701X VL - 10 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Herzschuh, Ulrike A1 - Cao, Xianyong A1 - Laepple, Thomas A1 - Dallmeyer, Anne A1 - Telford, Richard J. A1 - Ni, Jian A1 - Chen, Fahu A1 - Kong, Zhaochen A1 - Liu, Guangxiu A1 - Liu, Kam-Biu A1 - Liu, Xingqi A1 - Stebich, Martina A1 - Tang, Lingyu A1 - Tian, Fang A1 - Wang, Yongbo A1 - Wischnewski, Juliane A1 - Xu, Qinghai A1 - Yan, Shun A1 - Yang, Zhenjing A1 - Yu, Ge A1 - Zhang, Yun A1 - Zhao, Yan A1 - Zheng, Zhuo T1 - Position and orientation of the westerly jet determined Holocene rainfall patterns in China JF - Nature Communications N2 - Proxy-based reconstructions and modeling of Holocene spatiotemporal precipitation patterns for China and Mongolia have hitherto yielded contradictory results indicating that the basic mechanisms behind the East Asian Summer Monsoon and its interaction with the westerly jet stream remain poorly understood. We present quantitative reconstructions of Holocene precipitation derived from 101 fossil pollen records and analyse them with the help of a minimal empirical model. We show that the westerly jet-stream axis shifted gradually southward and became less tilted since the middle Holocene. This was tracked by the summer monsoon rain band resulting in an early-Holocene precipitation maximum over most of western China, a mid-Holocene maximum in north-central and northeastern China, and a late-Holocene maximum in southeastern China. Our results suggest that a correct simulation of the orientation and position of the westerly jet stream is crucial to the reliable prediction of precipitation patterns in China and Mongolia. Y1 - 2019 U6 - https://doi.org/10.1038/s41467-019-09866-8 SN - 2041-1723 VL - 10 PB - Nature Publ. Group CY - London ER - TY - GEN A1 - Angele, Bernhard A1 - Slattery, Timothy J. A1 - Yang, Jinmian A1 - Kliegl, Reinhold A1 - Rayner, Keith T1 - Parafoveal processing in reading: Manipulating n+1 and n+2 previews simultaneously N2 - The boundary paradigm (Rayner, 1975) with a novel preview manipulation was used to examine the extent of parafoveal processing of words to the right of fixation. Words n+1 and n+2 had either correct or incorrect previews prior to fixation (prior to crossing the boundary location). In addition, the manipulation utilized either a high or low frequency word in word n+1 location on the assumption that it would be more likely that n+2 preview effects could be obtained when word n+1 was high frequency. The primary findings were that there was no evidence for a preview benefit for word n+2 and no evidence for parafoveal-on-foveal effects when word n+1 is at least four letters long. We discuss implications for models of eye-movement control in reading. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - paper 251 Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-57128 ER - TY - JOUR A1 - Dambacher, Michael A1 - Slattery, Timothy J. A1 - Yang, Jinmian A1 - Kliegl, Reinhold A1 - Rayner, Keith T1 - Evidence for direct control of eye movements during reading JF - Journal of experimental psychology : Human perception and performance N2 - It is well established that fixation durations during reading vary with processing difficulty, but there are different views on how oculomotor control, visual perception, shifts of attention, and lexical (and higher cognitive) processing are coordinated. Evidence for a one-to-one translation of input delay into saccadic latency would provide a much needed constraint for current theoretical proposals. Here, we tested predictions of such a direct-control perspective using the stimulus-onset delay (SOD) paradigm. Words in sentences were initially masked and, on fixation, were individually unmasked with a delay (0-, 33-, 66-, 99-ms SODs). In Experiment 1, SODs were constant for all words in a sentence; in Experiment 2, SODs were manipulated on target words, while nontargets were unmasked without delay. In accordance with predictions of direct control, nonzero SODs entailed equivalent increases in fixation durations in both experiments. Yet, a population of short fixations pointed to rapid saccades as a consequence of low-level information at nonoptimal viewing positions rather than of lexical processing. Implications of these results for theoretical accounts of oculomotor control are discussed. KW - stimulus-onset delay KW - oculomotor control KW - fixation durations KW - sentence reading Y1 - 2013 U6 - https://doi.org/10.1037/a0031647 SN - 0096-1523 VL - 39 IS - 5 SP - 1468 EP - 1484 PB - American Psychological Association CY - Washington ER -