TY  - JOUR
A1  - Wessig, Pablo
A1  - Badetko, Dominik
A1  - Czarnecki, Maciej
A1  - Wichterich, Lukas
A1  - Schmidt, Peter
A1  - Brudy, Cosima
A1  - Sperlich, Eric
A1  - Kelling, Alexandra
T1  - Studies toward the total synthesis of arylnaphthalene lignans via a Photo-Dehydro-Diels-Alder (PDDA) reaction
JF  - The journal of organic chemistry
N2  - An efficient method for the preparation of arylnaphthalene lignans (ANLs) was developed, which is based on thePhoto-Dehydro-DIELS-ALDER(PDDA) reaction. While intermolecular PDDA reactions turned out to be inefficient, theintramolecular variant using suberic acid as tether linking two aryl propiolic esters smoothly provided naphthalenophanes. Theirradiations were performed with a previously developed annular continuous-flow reactor and UVB lamps. In this way, the naturalproducts Alashinol D, Taiwanin C, and an unnamed ANL could be prepared.
Y1  - 2022
U6  - https://doi.org/10.1021/acs.joc.2c00195
SN  - 0022-3263
SN  - 1520-6904
VL  - 87
IS  - 9
SP  - 5904
EP  - 5915
PB  - American Chemical Society
CY  - Washington
ER  -