TY  - JOUR
A1  - Grimm, Christiane
A1  - Meyer, Thomas
A1  - Czapla, Sylvia
A1  - Nikolaus, Jörg
A1  - Scheidt, Holger A.
A1  - Vogel, Alexander
A1  - Herrmann, Andreas
A1  - Wessig, Pablo
A1  - Huster, Daniel
A1  - Müller, Peter
T1  - Structure and dynamics of molecular rods in membranes application of a Spin-Labeled rod
JF  - Chemistry - a European journal
N2  - Molecular rods consisting of a hydrophobic backbone and terminally varying functional groups have been synthesized for applications for the functionalization of membranes. In the present study, we employ a spin-labeled analogue of a recently described new class of molecular rods to characterize their dynamic interactions with membranes. By using the different approaches of ESR and NMR spectroscopy, we show that the spin moiety of the membrane-embedded spin-labeled rod is localized in the upper chain/glycerol region of membranes of different compositions. The rod is embedded within the membrane in a tilted orientation to adjust for the varying hydrophobic thicknesses of these bilayers. This orientation does not perturb the membrane structure. The water solubility of the rod is increased significantly in the presence of certain cyclodextrins. These cyclodextrins also allow the rods to be extracted from the membrane and incorporated into preformed membranes. The latter will improve the future applications of these rods in cellular systems as stable membrane-associated anchors for the functionalization of membrane surfaces.
KW  - hydrophobic mismatch
KW  - membranes
KW  - molecular rods
KW  - phospholipids
KW  - spiro compounds
Y1  - 2013
U6  - https://doi.org/10.1002/chem.201202500
SN  - 0947-6539
VL  - 19
IS  - 8
SP  - 2703
EP  - 2710
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Tracy, Rosemarie
A1  - Heide, Judith
A1  - Wahl, Michael
A1  - Triarchi-Herrmann, Vassilia
A1  - Grimm, Angela
A1  - Wotschack, Christiane
A1  - Kulik, Sylvia
A1  - Frank, Ulrike
A1  - Klassert, Annegret
A1  - Gagarina, Natalʹja Vladimirovna
A1  - Kauschke, Christina
A1  - Eicher, Iris
A1  - Tsakmaki, Barbara
A1  - Akkaya, Zeynep
A1  - Castillo, Esmeralda
A1  - Groba, Agnes
A1  - Höhle, Barbara
A1  - Miertsch, Barbara
A1  - Hubert, Anja
A1  - Sauerland, Uli
A1  - Schröder, Caroline
A1  - Stadie, Nicole
A1  - Wittler, Marion
A1  - Berendes, Karin
A1  - Gottal, Stephanie
A1  - Grabherr, Britta
A1  - Zaps, Jennifer
A1  - Ptok, Martin
A1  - Hanne, Sandra
A1  - Sekerina, Irina A.
A1  - Vasishth, Shravan
A1  - Burchert, Frank
A1  - De Bleser, Ria
A1  - Kleissendorf, Barbara
A1  - Jaecks, Petra
A1  - Stenneken, Prisca
A1  - Fischer, Ivette
A1  - Moedebeck, Petra
ED  - Heide, Judith
ED  - Hanne, Sandra
ED  - Brandt-Kobele, Oda-Christina
ED  - Fritzsche, Tom
T1  - Spektrum Patholinguistik = Schwerpunktthema: Ein Kopf - Zwei Sprachen : Mehrsprachigkeit in Forschung und Therapie
N2  - "Spektrum Patholinguistik" (Band 2) ist der Tagungsband zum 2. Herbsttreffen Patholinguistik, das der Verband für Patholinguistik (vpl) e.V. am 22.11.2008 an der Universität Potsdam veranstaltet hat. Zum Schwerpunktthema "Ein Kopf - Zwei Sprachen: Mehrsprachigkeit in Forschung und Therapie" sind die drei Hauptvorträge und vier Abstracts von Posterpräsentationen veröffentlicht. Desweiteren enthält der Tagungsband freie Beiträge, u.a. zu Satzverarbeitung und Agrammatismus, Lesestrategien und LRS, Prosodie-Entwicklung, kindlichen Aphasien, Dysphagie-Therapie sowie zu kognitiven Defiziten bei älteren Menschen.
N2  - "Spektrum Patholinguistik" (vol. 2) contains the proceedings of the "2nd Herbsttreffen Patholinguistik" which was held at the University of Potsdam on November 22, 2008. Many talks and posters focused on bilingual language processing in normal and impaired speakers. The other contributions covered various topics, e.g. sentence processing and agrammatism, reading strategies and developmental dyslexia, language development, childhood aphasia, dysphagia therapy and cognitive skills in aging.
T3  - Spektrum Patholinguistik - 2 
KW  - Patholinguistik
KW  - Bilingualismus
KW  - Mehrsprachigkeit
KW  - Sprachtherapie
KW  - Sprachförderung
KW  - patholinguistics
KW  - bilingualism
KW  - speech and language therapy
Y1  - 2009
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-30451
SN  - 978-3-940793-89-8
SN  - 1869-3822
SN  - 1866-9433
IS  - 2
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  -