TY  - CHAP
A1  - Heinisch, Isabelle
A1  - Romeike, Ralf
A1  - Knobelsdorf, Maria
A1  - Kreitz, Christoph
A1  - Nylén, Aletta
A1  - Dörge, Christina
A1  - Göttel, Timo
A1  - Holz, Jan
A1  - Bergner, Nadine
A1  - Schroeder, Ulrik
A1  - Metzger, Christiane
A1  - Haag, Johann
A1  - Abke, Jörg
A1  - Schwirtlich, Vincent
A1  - Sedelmaier, Yvonne
A1  - Müller, Dorothee
A1  - Frommer, Andreas
A1  - Humbert, Ludger
A1  - Berges, Marc
A1  - Mühling, Andreas
A1  - Hubwieser, Peter
A1  - Steuer, Horst
A1  - Engbring, Dieter
A1  - Selke, Harald
A1  - Drews, Paul
A1  - Schirmer, Ingrid
A1  - Morisse, Marcel
A1  - Sagawe, Arno
A1  - Rolf, Arno
A1  - Friedemann, Stefan
A1  - Gröger, Stefan
A1  - Schumann, Matthias
A1  - Klinger, Melanie
A1  - Polutina, Olena
A1  - Bibel, Ariane
A1  - Götz, Christian
A1  - Brinda, Torsten
A1  - Apel, Rebecca
A1  - Berg, Tobias
A1  - Bergner, Nadine
A1  - Chatti, Mohamed Amine
A1  - Leicht-Scholten, Carmen
A1  - Schroeder, Ulrik
A1  - Al-Saffar, Loay Talib
A1  - Petre, Marian
A1  - Schirmer, Ingrid
A1  - Rick, Detlef
ED  - Forbrig, Peter
ED  - Rick, Detlef
ED  - Schmolitzky, Axel
T1  - HDI 2012 – Informatik für eine nachhaltige Zukunft : 5. Fachtagung Hochschuldidaktik der Informatik ; 06.–07. November 2012, Universität Hamburg
N2  - Die Tagungsreihe zur Hochschuldidaktik der Informatik HDI wird vom Fachbereich Informatik und Ausbildung / Didaktik der Informatik (IAD) in der Gesellschaft für Informatik e. V. (GI) organisiert. Sie dient den Lehrenden der Informatik in Studiengängen an Hochschulen als Forum der Information und des Austauschs über neue didaktische Ansätze und bildungspolitische Themen im Bereich der Hochschulausbildung aus der fachlichen Perspektive der Informatik. Diese fünfte HDI 2012 wurde an der Universität Hamburg organisiert. Für sie wurde das spezielle Motto „Informatik für eine nachhaltige Zukunft“ gewählt, um insbesondere Fragen der Bildungsrelevanz informatischer Inhalte, der Kompetenzen für Studierende informatisch geprägter Studiengänge und der Rolle der Informatik in der Hochschulentwicklung zu diskutieren.
T3  - Commentarii informaticae didacticae (CID) - 5 
Y1  - 2013
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62891
SN  - 978-3-86956-220-9
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - CHAP
A1  - Froitzheim, Manuel
A1  - Bergner, Nadine
A1  - Schroeder, Ulrik
A1  - Hurtienne, Dominik
A1  - Spannagel, Christian
A1  - Roderus, Simon
A1  - Wienkop, Uwe
A1  - Leonhardt, Thiemo
A1  - Kwiecien, Alexandra
A1  - Schmetz, Arno
A1  - Bellgardt, Martin
A1  - Naumann, Uwe
A1  - Weßels, Doris
A1  - Metzger, Christiane
A1  - Längrich, Matthias
A1  - Schulze, Jörg
A1  - Jakoblew, Marcel
A1  - Keil, Reinhard
A1  - Winkelnkemper, Felix
A1  - Engbring, Dieter
A1  - Klar, Tilman-Mathies
A1  - Kujath, Bertold
A1  - Schütze, Christopher
A1  - Fietkau, Julian
A1  - Kindsmüller, Martin Christof
A1  - Göttel, Timo
A1  - Bergner, Nadine
A1  - Taraschewski, Christian
A1  - Vosseberg, Karin
A1  - Czernik, Sofie
A1  - Erb, Ulrike
A1  - Vielhaber, Michael
A1  - Schlierkamp, Kathrin
A1  - Thurner, Veronika
A1  - Bröker, Kathrin
ED  - Forbrig, Peter
ED  - Magenheim, Johannes
T1  - HDI 2014 – Gestalten von Übergängen
BT  - 6. Fachtagung Hochschuldidaktik der Informatik ; 15.-16. September 2014, Universität Freiburg
N2  - Die Tagung HDI 2014 in Freiburg zur Hochschuldidaktik der Informatik HDI wurde erneut vom Fachbereich Informatik und Ausbildung / Didaktik der Informatik (IAD) in der Gesellschaft für Informatik e. V. (GI) organisiert. Sie dient den Lehrenden der Informatik in Studiengängen an Hochschulen als Forum der Information und des Austauschs über neue didaktische Ansätze und bildungspolitische Themen im Bereich der Hochschulausbildung aus der fachlichen Perspektive der Informatik.
Die HDI 2014 ist nun bereits die sechste Ausgabe der HDI. Für sie wurde das spezielle Motto „Gestalten und Meistern von Übergängen“ gewählt. Damit soll ein besonderes Augenmerk auf die Übergänge von Schule zum Studium, vom Bachelor zum  Master, vom Studium zur Promotion oder vom Studium zur Arbeitswelt gelegt werden.
T3  - Commentarii informaticae didacticae (CID) - 9 
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-74920
SN  - 978-3-86956-313-8
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Schmidt, Carsten
A1  - Schierack, Peter
A1  - Gerber, Ulrike
A1  - Schroeder, Christian
A1  - Choi, Youngeun
A1  - Bald, Ilko
A1  - Lehmann, Werner
A1  - Rödiger, Stefan
T1  - Streptavidin homologues for applications on solid surfaces at high temperatures
JF  - Langmuir
N2  - One of the most commonly used bonds between two biomolecules is the bond between biotin and streptavidin (SA) or streptavidin homologues (SAHs). A high dissociation constant and the consequent high-temperature stability even allows for its use in nucleic acid detection under polymerase chain reaction (PCR) conditions. There are a number of SAHs available, and for assay design, it is of great interest to determine as to which SAH will perform the best under assay conditions. Although there are numerous single studies on the characterization of SAHs in solution or selected solid phases, there is no systematic study comparing different SAHs for biomolecule-binding, hybridization, and PCR assays on solid phases. We compared streptavidin, core streptavidin, traptavidin, core traptavidin, neutravidin, and monomeric streptavidin on the surface of microbeads (10-15 mu m in diameter) and designed multiplex microbead-based experiments and analyzed simultaneously the binding of biotinylated oligonucleotides and the hybridization of oligonucleotides to complementary capture probes. We also bound comparably large DNA origamis to capture probes on the microbead surface. We used a real-time fluorescence microscopy imaging platform, with which it is possible to subject samples to a programmable time and temperature profile and to record binding processes on the microbead surface depending on the time and temperature. With the exception of core traptavidin and monomeric streptavidin, all other SA/SAHs were suitable for our investigations. We found hybridization efficiencies close to 100% for streptavidin, core streptavidin, traptavidin, and neutravidin. These could all be considered equally suitable for hybridization, PCR applications, and melting point analysis. The SA/SAH-biotin bond was temperature sensitive when the oligonucleotide was mono-biotinylated, with traptavidin being the most stable followed by streptavidin and neutravidin. Mono-biotinylated oligonucleotides can be used in experiments with temperatures up to 70 degrees C. When oligonucleotides were bis-biotinylated, all SA/SAH-biotin bonds had similar temperature stability under PCR conditions, even if they comprised a streptavidin variant with slower biotin dissociation and increased mechanostability.
Y1  - 2020
U6  - https://doi.org/10.1021/acs.langmuir.9b02339
SN  - 0743-7463
VL  - 36
IS  - 2
SP  - 628
EP  - 636
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Schmidt, Carsten
A1  - Roediger, Stefan
A1  - Gruner, Melanie
A1  - Moncsek, Anja
A1  - Stohwasser, Ralf
A1  - Hanack, Katja
A1  - Schierack, Peter
A1  - Schroeder, Christian
T1  - Multiplex localization of sequential peptide epitopes by use of a planar microbead chip
JF  - Analytica chimica acta : an international journal devoted to all branches of analytical chemistry
N2  - Epitope mapping is crucial for the characterization of protein-specific antibodies. Commonly, small overlapping peptides are chemically synthesized and immobilized to determine the specific peptide sequence. In this study, we report the use of a fast and inexpensive planar microbead chip for epitope mapping. We developed a generic strategy for expressing recombinant peptide libraries instead of using expensive synthetic peptide libraries. A biotin moiety was introduced in vivo at a defined peptide position using biotin ligase. Peptides in crude Escherichia coli lysate were coupled onto streptavidin-coated microbeads by incubation, thereby avoiding tedious purification procedures. For read-out we used a multiplex planar microbead chip with size- and fluorescence-encoded microbead populations. For epitope mapping, up to 18 populations of peptide-loaded microbeads (at least 20 microbeads per peptide) displaying the primary sequence of a protein were analyzed simultaneously. If an epitope was recognized by an antibody, a secondary fluorescence-labeled antibody generated a signal that was quantified, and the mean value of all microbeads in the population was calculated. We mapped the epitopes for rabbit anti-PA28 gamma (proteasome activator 28 gamma) polyclonal serum, for a murine monoclonal antibody against PA28 gamma, and for a murine monoclonal antibody against the hamster polyoma virus major capsid protein VP1 as models. In each case, the identification of one distinct peptide sequence out of up to 18 sequences was possible. Using this approach, an epitope can be mapped multiparametrically within three weeks. (C) 2016 Elsevier B.V. All rights reserved.
KW  - Epitope mapping
KW  - In vivo biotinylation
KW  - Multiplexed assays
KW  - Microbeads
KW  - VideoScan technology
Y1  - 2016
U6  - https://doi.org/10.1016/j.aca.2015.12.030
SN  - 0003-2670
SN  - 1873-4324
VL  - 908
SP  - 150
EP  - 160
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bergner, Nadine
A1  - Taraschewski, Christian
A1  - Schroeder, Ulrik
ED  - Schubert, Sigrid
ED  - Schwill, Andreas
T1  - Beispiel eines Schülerwettbewerbs zum Thema Projektmanagement und App-Programmierung
JF  - HDI 2014 : Gestalten von Übergängen
N2  - Es wird ein Informatik-Wettbewerb für Schülerinnen und Schüler der Sekundarstufe II beschrieben, der über mehrere Wochen möglichst realitätsnah die Arbeitswelt eines Informatikers vorstellt. Im Wettbewerb erarbeiten die Schülerteams eine Android-App und organisieren ihre Entwicklung durch Projektmanagementmethoden, die sich an professionellen, agilen Prozessen orientieren. Im Beitrag werden der theoretische Hintergrund zu Wettbewerben, die organisatorischen und didaktischen Entscheidung, eine erste Evaluation sowie Reflexion und Ausblick dargestellt.
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-84726
VL  - 2015
IS  - 9
SP  - 161
EP  - 168
ER  - 
TY  - JOUR
A1  - Hurtienne, Dominik
A1  - Schroeder, Ulrik
A1  - Spannagel, Christian
ED  - Schwill, Andreas
ED  - Schubert, Sigrid
T1  - IT EnGAGES!
BT  - Adaptierbare Gamification in einer Anfänger-Programmiervorlesung
JF  - HDI 2014 : Gestalten von Übergängen
N2  - Durch den Einsatz von Spielen und Spielelementen in Lernkontexten wird versucht, Lernende zur Beschäftigung mit den Lerninhalten zu motivieren. Spielerische Elemente haben allerdings nicht nur positive motivationale Effekte: Sie können sich beispielsweise negativ auf die intrinsische Motivation auswirken, und auch nicht jeder Lernende spielt gerne. Um negativen Einflüssen von Gamification entgegenzuwirken, wurde ein Toolkit für adaptierbare Lernumgebungen entwickelt. Damit erzeugte Lernumgebungen erlauben es Studierenden, den Grad der Gamification selbst zu bestimmen, indem Spielelemente an- und abgeschaltet werden. Im Rahmen einer Anfängerprogrammiervorlesung wurden Lernspielaufgaben aus den existierenden, optionalen interaktiven eTests entwickelt und Studierenden als zusätzliche Lerngelegenheit angeboten. Eine erste explorative Studie bestätigt die Vermutung, dass die Akzeptanz des adaptierbaren Lernspiels sehr hoch ist, es aber dennoch Studierende gibt, welche die Lernumgebung ohne Spielelemente durcharbeiten. Somit bietet adaptierbare Gamification verschiedenen Studierenden die Möglichkeit, sich zusätzliche motivationale Anreize durch Zuschalten von Spielelementen zu verschaffen, ohne dabei zum Spielen „genötigt“ zu werden.
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-80258
VL  - 2015
IS  - 9
SP  - 27
EP  - 43
ER  - 
TY  - JOUR
A1  - Ahnen, M. L.
A1  - Ansoldi, S.
A1  - Antonelli, L. A.
A1  - Arcaro, C.
A1  - Babie, A.
A1  - Banerjee, B.
A1  - Bangale, P.
A1  - de Almeida, U. Barres
A1  - Barrio, J. A.
A1  - Gonzalez, J. Becerra
A1  - Bednarek, W.
A1  - Bernardini, E.
A1  - Berti, A.
A1  - Biasuzzi, B.
A1  - Biland, A.
A1  - Blanch, O.
A1  - Bonnefoy, S.
A1  - Bonnoli, G.
A1  - Borracci, F.
A1  - Carosi, R.
A1  - Carosi, A.
A1  - Chatterjee, A.
A1  - Colin, P.
A1  - Colombo, E.
A1  - Contreras, J. L.
A1  - Cortina, J.
A1  - Covino, S.
A1  - Cumani, P.
A1  - Da Vela, P.
A1  - Dazzi, F.
A1  - De Angelis, A.
A1  - De Lotto, B.
A1  - Wilhelmi, E. de Ona
A1  - Di Pierro, F.
A1  - Doert, M.
A1  - Dominguez, A.
A1  - Prester, D. Dominis
A1  - Dorner, D.
A1  - Doro, M.
A1  - Einecke, S.
A1  - Glawion, D. Eisenacher
A1  - Elsaesser, D.
A1  - Engelkemeier, M.
A1  - Ramazani, V. Fallah
A1  - Fernandez-Barra, A.
A1  - Fidalgo, D.
A1  - Fonseca, M. V.
A1  - Font, L.
A1  - Fruck, C.
A1  - Galindo, D.
A1  - Lopez, R. J. Garcia
A1  - Garczarczyk, M.
A1  - Gaug, M.
A1  - Giammaria, P.
A1  - Godinovie, N.
A1  - Gora, D.
A1  - Griffiths, S.
A1  - Guberman, D.
A1  - Hadasch, D.
A1  - Hahn, A.
A1  - Hassan, T.
A1  - Hayashida, M.
A1  - Herrera, J.
A1  - Hose, J.
A1  - Hrupec, D.
A1  - Hughes, G.
A1  - Ishio, K.
A1  - Konno, Y.
A1  - Kubo, H.
A1  - Kushida, J.
A1  - Kuvezdie, D.
A1  - Lelas, D.
A1  - Lindfors, E.
A1  - Lombardi, S.
A1  - Longo, F.
A1  - Lopez, M.
A1  - Lopez-Oramas, A.
A1  - Majumdar, P.
A1  - Makariev, M.
A1  - Maneva, G.
A1  - Manganaro, M.
A1  - Mannheim, K.
A1  - Maraschi, L.
A1  - Mariotti, M.
A1  - Martinez, M.
A1  - Mazin, D.
A1  - Menzel, U.
A1  - Minev, M.
A1  - Mirzoyan, R.
A1  - Moralejo, A.
A1  - Moreno, V.
A1  - Moretti, E.
A1  - Munar-Adrover, P.
A1  - Neustroev, V.
A1  - Niedzwiecki, A.
A1  - Rosillo, M. Nievas
A1  - Nilsson, K.
A1  - Nishijima, K.
A1  - Noda, K.
A1  - Nogues, L.
A1  - Paiano, S.
A1  - Palacio, J.
A1  - Paneque, D.
A1  - Paoletti, R.
A1  - Paredes, J. M.
A1  - Paredes-Fortuny, X.
A1  - Pedaletti, G.
A1  - Peresano, M.
A1  - Perri, L.
A1  - Persic, M.
A1  - Moroni, P. G. Prada
A1  - Prandini, E.
A1  - Puljak, I.
A1  - Garcia, J. R.
A1  - Reichardt, I.
A1  - Rhode, W.
A1  - Riti, M.
A1  - Rico, J.
A1  - Saito, T.
A1  - Satalecka, K.
A1  - Schroeder, S.
A1  - Schweizer, T.
A1  - Shore, S. N.
A1  - Sillanpaa, A.
A1  - Sitarek, J.
A1  - Sobczynskall, D.
A1  - Stamerra, A.
A1  - Strzys, M.
A1  - Surie, T.
A1  - Takalo, L.
A1  - Tavecchio, F.
A1  - Temnikov, P.
A1  - Terzie, T.
A1  - Tescaro, D.
A1  - Teshima, M.
A1  - Torres, D. F.
A1  - Torres-Alla, N.
A1  - Treves, A.
A1  - Vanzo, G.
A1  - Acosta, M. Vazquez
A1  - Vovk, I.
A1  - Ward, J. E.
A1  - Will, M.
A1  - Wu, M. H.
A1  - Zarie, D.
A1  - Abdalla, Hassan E.
A1  - Abramowski, A.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Akhperjanian, A. G.
A1  - Andersson, T.
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arrieta, M.
A1  - Aubert, P.
A1  - Backes, M.
A1  - Balzer, A.
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Tjus, J. Becker
A1  - Berge, D.
A1  - Bernhard, S.
A1  - Bernlohr, K.
A1  - Blackwell, R.
A1  - Bottcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bordas, Pol
A1  - Bregeon, J.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Btichele, M.
A1  - Bulik, T.
A1  - Capasso, M.
A1  - Carr, J.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chakraborty, N.
A1  - Chalme-Calvet, R.
A1  - Chaves, R. C. G.
A1  - Chen, A.
A1  - Chevalier, J.
A1  - Chretien, M.
A1  - Coffaro, M.
A1  - Colafrancesco, S.
A1  - Cologna, G.
A1  - Condon, B.
A1  - Conrad, J.
A1  - Cui, Y.
A1  - Davids, I. D.
A1  - Decock, J.
A1  - Degrange, B.
A1  - Dei, C.
A1  - Devin, J.
A1  - Dewilt, P.
A1  - Dirson, L.
A1  - Djannati-Atai, A.
A1  - Domainko, W.
A1  - Donath, A.
A1  - Dutson, K.
A1  - Dyks, J.
A1  - Edwards, T.
A1  - Egberts, Kathrin
A1  - Eger, P.
A1  - Ernenwein, J. -P.
A1  - Eschbach, S.
A1  - Farnier, C.
A1  - Fegan, S.
A1  - Fernandes, M. V.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Forster, A.
A1  - Funk, S.
A1  - Ftifiling, M.
A1  - Gabici, S.
A1  - Gajdus, M.
A1  - Gallant, Y. A.
A1  - Garrigoux, T.
A1  - Giavitto, G.
A1  - Giebels, B.
A1  - Glicenstein, J. F.
A1  - Gottschal, D.
A1  - Goya, A.
A1  - Grondin, M. -H.
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Hawkes, J.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hervet, O.
A1  - Hinton, J. A.
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holler, M.
A1  - Horns, D.
A1  - Ivascenko, A.
A1  - Iwasaki, H.
A1  - Jacholkowska, A.
A1  - Jamrozy, M.
A1  - Janiak, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jingo, M.
A1  - Jogler, T.
A1  - Jouvin, L.
A1  - Jung-Richardt, I.
A1  - Kastendieck, M. A.
A1  - Katarzyfiski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Kerszberg, D.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - Kieffer, M.
A1  - King, J.
A1  - Klepser, S.
A1  - Klochkov, D.
A1  - Kluiniak, W.
A1  - Kolitzus, D.
A1  - Komin, Nu.
A1  - Kosack, K.
A1  - Krakau, S.
A1  - Kraus, M.
A1  - Krtiger, P. P.
A1  - Laffon, H.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lees, J. -P.
A1  - Lefaucheur, J.
A1  - Lefranc, V.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J. -P.
A1  - Leser, Eva
A1  - Lohse, T.
A1  - Lorentz, M.
A1  - Liu, R.
A1  - Lopez-Coto, R.
A1  - Lypova, I.
A1  - Marandon, V.
A1  - Marcowith, Alexandre
A1  - Mariaud, C.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Maxted, N.
A1  - Mayer, M.
A1  - Meintjes, P. J.
A1  - Meyer, M.
A1  - Mitche, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Mora, K.
A1  - Moulin, Emmanuel
A1  - Murach, T.
A1  - Nakashima, S.
A1  - De Naurois, M.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ott, S.
A1  - Ohm, S.
A1  - Ostrowski, M.
A1  - Oya, I.
A1  - Padovani, M.
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Pekeur, N. W.
A1  - Pelletier, G.
A1  - Perennes, C.
A1  - Petrucci, P. -O.
A1  - Peyaud, B.
A1  - Pie, Q.
A1  - Pita, S.
A1  - Poon, H.
A1  - Prokhorov, D.
A1  - Prokoph, H.
A1  - Ptffilhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Renaud, M.
A1  - De Los Reyes, R.
A1  - Richter, S.
A1  - Rieger, F.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Rulten, C. B.
A1  - Safi-Harb, S.
A1  - Sahakian, V.
A1  - Saito, S.
A1  - Salek, D.
A1  - Sanchez, D. A.
A1  - Santangelo, A.
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schtissler, F.
A1  - Schulz, A.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Settimo, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shilon, I.
A1  - Simoni, R.
A1  - So, H.
A1  - Spanier, F.
A1  - Spengler, G.
A1  - Spies, F.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Stycz, K.
A1  - Sushch, I.
A1  - Takahashi, T.
A1  - Tavernet, J. -P.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tibaldo, L.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - Van der Walt, D. J.
A1  - Van Eldik, C.
A1  - Van Rensburg, C.
A1  - Van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Viana, A.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Vok, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - Wagner, P.
A1  - Wagner, R. M.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Willmann, P.
A1  - Wornlein, A.
A1  - Wouters, D.
A1  - Yang, R.
A1  - Zabalza, V.
A1  - Zaborov, D.
A1  - Zacharias, M.
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Zefi, F.
A1  - Ziegler, A.
A1  - Zywuckan, N.
T1  - Constraints on particle acceleration in SS433/W50 from MAGIC and HESS observations
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context. The large jet kinetic power and non-thermal processes occurring in the microquasar SS 433 make this source a good candidate for a very high-energy (VHE) gamma-ray emitter. Gamma-ray fluxes above the sensitivity limits of current Cherenkov telescopes have been predicted for both the central X-ray binary system and the interaction regions of SS 433 jets with the surrounding W50 nebula. Non-thermal emission at lower energies has been previously reported, indicating that efficient particle acceleration is taking place in the system. Aims. We explore the capability of SS 433 to emit VHE gamma rays during periods in which the expected flux attenuation due to periodic eclipses (P-orb similar to 13.1 days) and precession of the circumstellar disk (P-pre similar to 162 days) periodically covering the central binary system is expected to be at its minimum. The eastern and western SS 433/W50 interaction regions are also examined using the whole data set available. We aim to constrain some theoretical models previously developed for this system with our observations. Methods. We made use of dedicated observations from the Major Atmospheric Gamma Imaging Cherenkov telescopes (MAGIC) and High Energy Spectroscopic System (H.E.S.S.) of SS 433 taken from 2006 to 2011. These observation were combined for the first time and accounted for a total effective observation time of 16.5 h, which were scheduled considering the expected phases of minimum absorption of the putative VHE emission. Gamma-ray attenuation does not affect the jet/medium interaction regions. In this case, the analysis of a larger data set amounting to similar to 40-80 h, depending on the region, was employed. Results. No evidence of VHE gamma-ray emission either from the central binary system or from the eastern/western interaction regions was found. Upper limits were computed for the combined data set. Differential fluxes from the central system are found to be less than or similar to 10(-12)-10(-13) TeV-1 cm(-2) s(-1) in an energy interval ranging from similar to few x 100 GeV to similar to few TeV. Integral flux limits down to similar to 10(-12)-10(-13) ph cm(-2) s(-1) and similar to 10(-13)-10(-14) ph cm(-2) s(-1) are obtained at 300 and 800 GeV, respectively. Our results are used to place constraints on the particle acceleration fraction at the inner jet regions and on the physics of the jet/medium interactions. Conclusions. Our findings suggest that the fraction of the jet kinetic power that is transferred to relativistic protons must be relatively small in SS 433, q(p) <= 2.5 x 10(-5), to explain the lack of TeV and neutrino emission from the central system. At the SS 433/W50 interface, the presence of magnetic fields greater than or similar to 10 mu G is derived assuming a synchrotron origin for the observed X-ray emission. This also implies the presence of high-energy electrons with E-e up to 50 TeV, preventing an efficient production of gamma-ray fluxes in these interaction regions.
KW  - gamma rays: general
KW  - stars: black holes
KW  - X-rays: binaries
KW  - ISM: jets and outflows
Y1  - 2018
U6  - https://doi.org/10.1051/0004-6361/201731169
SN  - 1432-0746
VL  - 612
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Jeltsch, Florian
A1  - Blaum, Niels
A1  - Brose, Ulrich
A1  - Chipperfield, Joseph D.
A1  - Clough, Yann
A1  - Farwig, Nina
A1  - Geissler, Katja
A1  - Graham, Catherine H.
A1  - Grimm, Volker
A1  - Hickler, Thomas
A1  - Huth, Andreas
A1  - May, Felix
A1  - Meyer, Katrin M.
A1  - Pagel, Jörn
A1  - Reineking, Björn
A1  - Rillig, Matthias C.
A1  - Shea, Katriona
A1  - Schurr, Frank Martin
A1  - Schroeder, Boris
A1  - Tielbörger, Katja
A1  - Weiss, Lina
A1  - Wiegand, Kerstin
A1  - Wiegand, Thorsten
A1  - Wirth, Christian
A1  - Zurell, Damaris
T1  - How can we bring together empiricists and modellers in functional biodiversity research?
JF  - Basic and applied ecology : Journal of the Gesellschaft für Ökologie
N2  - Improving our understanding of biodiversity and ecosystem functioning and our capacity to inform ecosystem management requires an integrated framework for functional biodiversity research (FBR). However, adequate integration among empirical approaches (monitoring and experimental) and modelling has rarely been achieved in FBR. We offer an appraisal of the issues involved and chart a course towards enhanced integration. A major element of this path is the joint orientation towards the continuous refinement of a theoretical framework for FBR that links theory testing and generalization with applied research oriented towards the conservation of biodiversity and ecosystem functioning. We further emphasize existing decision-making frameworks as suitable instruments to practically merge these different aims of FBR and bring them into application. This integrated framework requires joint research planning, and should improve communication and stimulate collaboration between modellers and empiricists, thereby overcoming existing reservations and prejudices. The implementation of this integrative research agenda for FBR requires an adaptation in most national and international funding schemes in order to accommodate such joint teams and their more complex structures and data needs.
KW  - Biodiversity theory
KW  - Biodiversity experiments
KW  - Conservation management
KW  - Decision-making
KW  - Ecosystem functions and services
KW  - Forecasting
KW  - Functional traits
KW  - Global change
KW  - Monitoring programmes
KW  - Interdisciplinarity
Y1  - 2013
U6  - https://doi.org/10.1016/j.baae.2013.01.001
SN  - 1439-1791
VL  - 14
IS  - 2
SP  - 93
EP  - 101
PB  - Elsevier
CY  - Jena
ER  -