TY - JOUR A1 - Cahsan, Binia De A1 - Westbury, Michael V. A1 - Paraskevopoulou, Sofia A1 - Drews, Hauke A1 - Ott, Moritz A1 - Gollmann, Günter A1 - Tiedemann, Ralph T1 - Genomic consequences of human-mediated translocations in margin populations of an endangered amphibian JF - Evolutionary Applications N2 - Due to their isolated and often fragmented nature, range margin populations are especially vulnerable to rapid environmental change. To maintain genetic diversity and adaptive potential, gene flow from disjunct populations might therefore be crucial to their survival. Translocations are often proposed as a mitigation strategy to increase genetic diversity in threatened populations. However, this also includes the risk of losing locally adapted alleles through genetic swamping. Human-mediated translocations of southern lineage specimens into northern German populations of the endangered European fire-bellied toad (Bombina bombina) provide an unexpected experimental set-up to test the genetic consequences of an intraspecific introgression from central population individuals into populations at the species range margin. Here, we utilize complete mitochondrial genomes and transcriptome nuclear data to reveal the full genetic extent of this translocation and the consequences it may have for these populations. We uncover signs of introgression in four out of the five northern populations investigated, including a number of introgressed alleles ubiquitous in all recipient populations, suggesting a possible adaptive advantage. Introgressed alleles dominate at the MTCH2 locus, associated with obesity/fat tissue in humans, and the DSP locus, essential for the proper development of epidermal skin in amphibians. Furthermore, we found loci where local alleles were retained in the introgressed populations, suggesting their relevance for local adaptation. Finally, comparisons of genetic diversity between introgressed and nonintrogressed northern German populations revealed an increase in genetic diversity in all German individuals belonging to introgressed populations, supporting the idea of a beneficial transfer of genetic variation from Austria into North Germany. KW - adaptive introgression KW - admixture KW - Bombina bombina KW - genetic rescue KW - mitogenomes KW - transcriptomics Y1 - 2020 SN - 1752-4563 VL - 14 IS - 6 PB - John Wiley & Sons, Inc. CY - New Jersey ER - TY - GEN A1 - Cahsan, Binia De A1 - Westbury, Michael V. A1 - Paraskevopoulou, Sofia A1 - Drews, Hauke A1 - Ott, Moritz A1 - Gollmann, Günter A1 - Tiedemann, Ralph T1 - Genomic consequences of human-mediated translocations in margin populations of an endangered amphibian T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Due to their isolated and often fragmented nature, range margin populations are especially vulnerable to rapid environmental change. To maintain genetic diversity and adaptive potential, gene flow from disjunct populations might therefore be crucial to their survival. Translocations are often proposed as a mitigation strategy to increase genetic diversity in threatened populations. However, this also includes the risk of losing locally adapted alleles through genetic swamping. Human-mediated translocations of southern lineage specimens into northern German populations of the endangered European fire-bellied toad (Bombina bombina) provide an unexpected experimental set-up to test the genetic consequences of an intraspecific introgression from central population individuals into populations at the species range margin. Here, we utilize complete mitochondrial genomes and transcriptome nuclear data to reveal the full genetic extent of this translocation and the consequences it may have for these populations. We uncover signs of introgression in four out of the five northern populations investigated, including a number of introgressed alleles ubiquitous in all recipient populations, suggesting a possible adaptive advantage. Introgressed alleles dominate at the MTCH2 locus, associated with obesity/fat tissue in humans, and the DSP locus, essential for the proper development of epidermal skin in amphibians. Furthermore, we found loci where local alleles were retained in the introgressed populations, suggesting their relevance for local adaptation. Finally, comparisons of genetic diversity between introgressed and nonintrogressed northern German populations revealed an increase in genetic diversity in all German individuals belonging to introgressed populations, supporting the idea of a beneficial transfer of genetic variation from Austria into North Germany. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1168 KW - adaptive introgression KW - admixture KW - Bombina bombina KW - genetic rescue KW - mitogenomes KW - transcriptomics Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-523140 SN - 1866-8372 IS - 6 ER - TY - JOUR A1 - Kiemel, Katrin A1 - De Cahsan, Binia A1 - Paraskevopoulou, Sofia A1 - Weithoff, Guntram A1 - Tiedemann, Ralph T1 - Mitochondrial genomes of the freshwater monogonont rotifer Brachionus fernandoi and of two additional B. calyciflorus sensu stricto lineages from Germany and the USA (Rotifera, Brachionidae) JF - Mitochondrial DNA. Part B-Resources N2 - The Brachionus calyciflorus species complex was recently subdivided into four species, but genetic resources to resolve phylogenetic relationships within this complex are still lacking. We provide two complete mitochondrial (mt) genomes from B. calyciflorus sensu stricto (Germany, USA) and the mt coding sequences (cds) from a German B. fernandoi. Phylogenetic analysis placed our B. calyciflorus sensu stricto strains close to the published genomes of B. calyciflorus, forming the putative sister species to B. fernandoi. Global representatives of B. calyciflorus sensu stricto (i.e. Europe, USA, and China) are genetically closer related to each other than to B. fernandoi (average pairwise nucleotide diversity 0.079 intraspecific vs. 0.254 interspecific). KW - Mitogenome KW - cryptic species KW - Brachionus calyciflorus s KW - Brachionus KW - fernandoi KW - monogonont rotifer Y1 - 2022 U6 - https://doi.org/10.1080/23802359.2022.2060765 SN - 2380-2359 VL - 7 IS - 4 SP - 646 EP - 648 PB - Routledge, Taylor & Francis Group CY - Abingdon ER -