TY - JOUR A1 - Scheller, Frieder W. A1 - Kleinjung, Frank A1 - Bier, Frank Fabian A1 - Markower, Alexander A1 - Neumann, Barbara A1 - Wollenberger, Ursula A1 - Kurochkin, Iliya N. A1 - Eremenko, Arkadi V. A1 - Barmin, Anatoli V. A1 - Klußmann, Sven A1 - Fürste, Jens-Peter A1 - Erdmann, Volker A. A1 - Mansuy, D. T1 - New recognition elements in biosensing Y1 - 1998 ER - TY - JOUR A1 - Costard, Sylvia A1 - Stadie, Nicole A1 - Ritter, Christiane A1 - Moll, Kristina A1 - Landerl, Karin A1 - Kohnen, Saskia A1 - Kentner, Gerrit A1 - Bethmann, Anja A1 - Scheich, Henning A1 - Brechmann, André A1 - De Kok, Dörte A1 - Berger, Frauke A1 - Sticher, Heike A1 - Czepluch, Christine A1 - Mätzener, Flurina A1 - Wilmes, Stefanie A1 - Hadert, Sandra A1 - Frank, Ulrike A1 - Mäder, Mark A1 - Westermann, Antje A1 - Meinusch, Miriam A1 - Neumann, Sandra A1 - Düsterhöft, Stefanie A1 - Posse, Dorothea A1 - Puritz, Caroline A1 - Seidl, Rainer Ottis A1 - Etzien, Maria A1 - Machleb, Franziska A1 - Lorenz, Antje A1 - Höger, Maria A1 - Schröder, Astrid A1 - Busch, Tobias A1 - Heide, Judith A1 - Tagoe, Tanja A1 - Watermeyer, Melanie A1 - Höhle, Barbara A1 - Kauschke, Christina ED - Hanne, Sandra ED - Fritzsche, Tom ED - Ott, Susan ED - Adelt, Anne T1 - Spektrum Patholinguistik = Schwerpunktthema: Lesen lernen: Diagnostik und Therapie bei Störungen des Leseerwerbs T1 - Spektrum Patholinguistik = Key issue: Learning to read: Assessment and intervention in developmental reading disorders N2 - Am 20. November 2010 fand an der Universität Potsdam das 4. Herbsttreffen Patholinguistik statt. Die Konferenzreihe wird regelmäßig seit 2007 vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Der vorliegende Tagungsband veröffentlicht die Hauptvorträge des Herbsttreffens zum Thema "Lesen lernen: Diagnostik und Therapie bei Störungen des Leseerwerbs". Des Weiteren sind die Beiträge promovierender bzw. promovierter PatholinguistInnen sowie der Posterpräsentationen enthalten. N2 - On November 20, 2010, the 4th Herbsttreffen Patholinguistik took place at the University of Potsdam. This annual conference is organized by the Verband für Patholinguistik e.V. (vpl). The main topic was "Learning to read: Assessment and intervention in developmental dyslexia". These proceedings contain the four main lectures, the contributed talks of the "Spektrum Patholinguistik" covering various psycho- and neurolinguistic research areas, and the abstracts of the presented posters. T3 - Spektrum Patholinguistik - 4 KW - Patholinguistik KW - Sprachtherapie KW - Leseerwerb KW - Dyslexie KW - Lese-Rechtschreib-Schwäche KW - patholinguistics KW - speech/language therapy KW - reading development KW - reading skills KW - dyslexia Y1 - 2011 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-53146 SN - 978-3-86956-145-5 SN - 1869-3822 SN - 1866-9433 IS - 4 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - GEN A1 - Paßlack, Nadine A1 - Schmiedchen, Bettina A1 - Raila, Jens A1 - Schweigert, Florian J. A1 - Stumpff, Friederike A1 - Kohn, Barbara A1 - Neumann, Konrad A1 - Zentek, Jürgen T1 - Impact of increasing dietary calcium levels on calcium excretion and vitamin D metabolites in the blood of healthy adult cats T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Background Dietary calcium (Ca) concentrations might affect regulatory pathways within the Ca and vitamin D metabolism and consequently excretory mechanisms. Considering large variations in Ca concentrations of feline diets, the physiological impact on Ca homeostasis has not been evaluated to date. In the present study, diets with increasing concentrations of dicalcium phosphate were offered to ten healthy adult cats (Ca/phosphorus (P): 6.23/6.02, 7.77/7.56, 15.0/12.7, 19.0/17.3, 22.2/19.9, 24.3/21.6 g/kg dry matter). Each feeding period was divided into a 10-day adaptation and an 8-day sampling period in order to collect urine and faeces. On the last day of each feeding period, blood samples were taken. Results Urinary Ca concentrations remained unaffected, but faecal Ca concentrations increased (P < 0.001) with increasing dietary Ca levels. No effect on whole and intact parathyroid hormone levels, fibroblast growth factor 23 and calcitriol concentrations in the blood of the cats were observed. However, the calcitriol precursors 25(OH)D-2 and 25(OH)D-3, which are considered the most useful indicators for the vitamin D status, decreased with higher dietary Ca levels (P = 0.013 and P = 0.033). Increasing dietary levels of dicalcium phosphate revealed an acidifying effect on urinary fasting pH (6.02) and postprandial pH (6.01) (P < 0.001), possibly mediated by an increase of urinary phosphorus (P) concentrations (P < 0.001). Conclusions In conclusion, calcitriol precursors were linearly affected by increasing dietary Ca concentrations. The increase in faecal Ca excretion indicates that Ca homeostasis of cats is mainly regulated in the intestine and not by the kidneys. Long-term studies should investigate the physiological relevance of the acidifying effect observed when feeding diets high in Ca and P. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 542 KW - chronic kidney-disease KW - growth-factor 23 KW - parathyroid-hormone KW - urinary ph KW - phosphorus KW - FGF23 KW - deficiency KW - dogs KW - hypercalciuria KW - secretion Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-411302 SN - 1866-8372 IS - 542 ER - TY - JOUR A1 - Passlack, Nadine A1 - Schmiedchen, Bettina A1 - Raila, Jens A1 - Schweigert, Florian J. A1 - Stumpff, Friederike A1 - Kohn, Barbara A1 - Neumann, Konrad A1 - Zentek, Juergen T1 - Impact of Increasing Dietary Calcium Levels on Calcium Excretion and Vitamin D Metabolites in the Blood of Healthy Adult Cats JF - PLoS one N2 - Background Dietary calcium (Ca) concentrations might affect regulatory pathways within the Ca and vitamin D metabolism and consequently excretory mechanisms. Considering large variations in Ca concentrations of feline diets, the physiological impact on Ca homeostasis has not been evaluated to date. In the present study, diets with increasing concentrations of dicalcium phosphate were offered to ten healthy adult cats (Ca/phosphorus (P): 6.23/6.02, 7.77/7.56, 15.0/12.7, 19.0/17.3, 22.2/19.9, 24.3/21.6 g/kg dry matter). Each feeding period was divided into a 10-day adaptation and an 8-day sampling period in order to collect urine and faeces. On the last day of each feeding period, blood samples were taken. Results Urinary Ca concentrations remained unaffected, but faecal Ca concentrations increased (P < 0.001) with increasing dietary Ca levels. No effect on whole and intact parathyroid hormone levels, fibroblast growth factor 23 and calcitriol concentrations in the blood of the cats were observed. However, the calcitriol precursors 25(OH)D-2 and 25(OH)D-3, which are considered the most useful indicators for the vitamin D status, decreased with higher dietary Ca levels (P = 0.013 and P = 0.033). Increasing dietary levels of dicalcium phosphate revealed an acidifying effect on urinary fasting pH (6.02) and postprandial pH (6.01) (P < 0.001), possibly mediated by an increase of urinary phosphorus (P) concentrations (P < 0.001). Conclusions In conclusion, calcitriol precursors were linearly affected by increasing dietary Ca concentrations. The increase in faecal Ca excretion indicates that Ca homeostasis of cats is mainly regulated in the intestine and not by the kidneys. Long-term studies should investigate the physiological relevance of the acidifying effect observed when feeding diets high in Ca and P. Y1 - 2016 U6 - https://doi.org/10.1371/journal.pone.0149190 SN - 1932-6203 VL - 11 SP - 47 EP - 67 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Rockström, Johan A1 - Kotzé, Louis A1 - Milutinović, Svetlana A1 - Biermann, Frank A1 - Brovkin, Victor A1 - Donges, Jonathan A1 - Ebbesson, Jonas A1 - French, Duncan A1 - Gupta, Joyeeta A1 - Kim, Rakhyun A1 - Lenton, Timothy A1 - Lenzi, Dominic A1 - Nakicenovic, Nebojsa A1 - Neumann, Barbara A1 - Schuppert, Fabian A1 - Winkelmann, Ricarda A1 - Bosselmann, Klaus A1 - Folke, Carl A1 - Lucht, Wolfgang A1 - Schlosberg, David A1 - Richardson, Katherine A1 - Steffen, Will T1 - The planetary commons BT - a new paradigm for safeguarding earth-regulating systems in the Anthropocene JF - Proceedings of the National Academy of Sciences of the United States of America N2 - The Anthropocene signifies the start of a no- analogue tra­jectory of the Earth system that is fundamentally different from the Holocene. This new trajectory is characterized by rising risks of triggering irreversible and unmanageable shifts in Earth system functioning. We urgently need a new global approach to safeguard critical Earth system regulating functions more effectively and comprehensively. The global commons framework is the closest example of an existing approach with the aim of governing biophysical systems on Earth upon which the world collectively depends. Derived during stable Holocene conditions, the global commons framework must now evolve in the light of new Anthropocene dynamics. This requires a fundamental shift from a focus only on governing shared resources beyond national jurisdiction, to one that secures critical functions of the Earth system irrespective of national boundaries. We propose a new framework—the planetary commons—which differs from the global commons frame­work by including not only globally shared geographic regions but also critical biophysical systems that regulate the resilience and state, and therefore livability, on Earth. The new planetary commons should articulate and create comprehensive stewardship obligations through Earth system governance aimed at restoring and strengthening planetary resilience and justice. KW - anthropocene KW - earth system governance KW - global commons KW - international law KW - planetary boundaries Y1 - 2024 U6 - https://doi.org/10.1073/pnas.2301531121 SN - 1091-6490 SN - 1877-2014 VL - 121 IS - 5 PB - National Academy of Sciences CY - Washington, DC ER -